5KA4A

Protein tyrosine phosphatase 1b t178a mutant, open state
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
280
structure length
280
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTAWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
total genus 91
structure length 280
sequence length 280
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2016-06-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 5ka4A00
3ZMPA 4WOHA 5HDEA 2F6VA 2NV5A 4J51A 4D3PA 5IBSA 2VEWA 1YTSA 1GWZA 1PTTA 2BGEA 2Y2FA 2C46A 4GS0A 4NWFA 1PXHA 4OHEA 2I1YA 1T49A 4JNBA 2VEXA 2J16A 2J17A 1ZCKA 2P6XA 2HCMA 2HB1A 2I42A 2H4VA 2CNIA 2OC3A 1RPMA 2CMCA 3CM3A 1PTVA 1KAKA 1XXVA 1G1FA 5K25A 4JMJA 5KABA 1LYVA 1OHEA 1LQFA 3O4SA 4GRZA 4HRFA 4B04A 2HXPA 4OHLA 3RGQA 4PVGA 1Q6MA 3EZZA 3O5XA 3V0EA 3MOWA 1L8GA 2G6ZA 4KYQA 2I4EA 5KADA 1ONZA 4WTYA 4H34A 1PA9A 2F6TA 1T4JA 4R30A 2I6IA 3D42A 1C83A 2SHPA 2NZ6A 1L8KA 2H02A 2OZ5A 2A8BA 4KYRA 4D3RA 4GE2A 2CFVA 4OHIA 4Y2EA 1QXKA 2BZLA 4GE5A 4NWGA 1PA1A 1YTNA 2QDMA 5J8RA 5MMZB 3BLTA 2AZRA 3V0HA 4ERCA 2CMBA 2H03A 1A5YA 3A5KA 3CWEA 5KA4A 2F70A 5BUGA 2QBRA 1OESA 3EAXA 2B3OA 1SUGA 5K24A 4DGXA 1LARA 4WU2A 3F9AA 2BIJA 2VEVA 3SMEA 3F41A 3EMUA 5KACA 2DXPA 1Q6SA 3N0AA 2H04A 1I9SA 4RH5A 3V0GA 2CNFA 5AWXA 1C86A 1G4US 2HNQA 3GXHA 2HC2A 2I3UA 2CNEA 5K9WA 3A5JA 1PYNA 2PQ5A 2I75A 2I4HA 2IMGA 2VEUA 1ECVA 4NX8A 1EENA 1YGUA 2I6JA 3AWGA 3QCNA 1NL9A 5KAAA 1Q6PA 1OEUA 1Q6JA 4Z6BA 4I8NA 2Y96A 3I36A 3RGOA 2ZMMA 4KI9A 5KA2A 2QDCA 2PI7A 3V0IA 4BJOA 3EU0A 2F6FA 3B7OA 2QBQA 3MMJA 3S3FA 2QBPA 2YDUA 1PH0A 2WGPA 3O4UA 3QCJA 4NNDA 3QCLA 2F6WA 2CJZA 4HJPA 1JLNA 1I9TA 2C7SA 5K9VA 1C87A 1MKPA 3ZV2A 1BZJA 3ZMQA 2CNHA 1X24A 2CM2A 1XXPA 2CNGA 2H4KA 1NZ7A 2QBSA 3QCDA 1OHDA 4RDDA 2PSZA 4GE6A 2PA5A 4GWFA 1ZZWA 3PS5A 5BX1A 5LXQB 3QCKA 2RF6A 3S3EA 4JBCA 3S3KA 2I5XA 1JF7A 4H1OA 1KAVA 2BGDA 3QKPA 2QCTA 1ZC0A 2B4SA 2I4GA 3QCCA 1U26A 5KA3A 4OHHA 1OEVA 3U96A 4RKKA 3F9BA 3BM8A 3I80A 3ZM3A 2HY3A 2FJNA 4YAAA 4ZN5A 4R0SA 4GFUA 3NMEA 1PTYA 1PTUA 1FQ1A 2ESBA 2A3KA 4DGPA 2BV5A 2FH7A 4QAPA 3S3HA 2CM7A 1FPRA 1R6HA 4ZI4A 3D9CA 2J16B 5BZXA 4JMKA 3QCHA 3BLUA 3F99A 1XRIA 2F6YA 1OEMX 2Q05A 3QCEA 2CM8A 3SR9A 1VHRA 1WAXA 1V3AA 2B07A 2I6MA 4IKCA 4RHGA 1GFYA 3ZM1A 1G4WR 2PBNA 4GRYA 1C85A 4ZRTA 4RI4A 1YGRA 4PYHA 4TVVA 3RO1A 4D3QA 5KA1A 4QBWA 1QZ0A 2GJTA 5EHPA 2F71A 2B49A 3H2XA 2CM3A 1G1GA 5IBMA 2F46A 2PT0A 1Q1MA 3D1HA 4R0TA 1NWLA 4MBBA 2I6PA 1XM2A 1WRMA 1ONYA 2NT7A 1NNYA 2VEYA 2CMAA 3QKQA 2AHSA 4HJQA 1AAXA 2H4GA 5KA9A 2MBCA 4RI5A 3I7ZA 1OETA 3D1QA 2R0BA 5I6VA 1OHCA 5K23A 3O3LA 3QCFA 2HVLA 3EB1A 3M4UA 5M43A 4S0GA 1XBOA 4BPCA 1P15A 2I3RA 1OEOX 2E0TA 4QAHA 3QCBA 2G59A 4Y14A 3V0FA 1Q6NA 3D44A 2B4PA 2B4UA 1FPZA 2B4OA 1J4XA 5KA7A 3ZM2A 2ZN7A 1RXDA 4RH9A 5EHRA 2HC1A 3BRHA 2FJMA 2OOQA 4QUNA 2GP0A 5K22A 1M3GA 2QEPA 4ICZA 2QDPA 2P4DA 5KA8A 2OUDA 4OHDA 3V0DA 1C84A 1NWEA 3OLRA 1YFOA 3S4EA 3QCGA 3RZ2A 4YR8B 1G7FA 3LJ8A 3QCIA 3AWFA 1EEOA 1YTWA 2GWOA 2NT2A 2Q47A 3D1OA 1BZHA 5KA0A 3GXGA 2NTAA 3QCMA 2JJDA 3O4TA 4GFVA 1T48A 1U24A 1BZCA 3ZM0A 1NO6A 4QBEA 1YZ4A 1WCHA 1YPTA 3F81A 2HNPA 1G7GA 2F6ZA 3OMHA 4QUMA 2I6OA 3V0JA 3AWEA 1YN9A 2NLKA 3MOZA 1I57A 4AZ1A 1G1HA 4NYHA 2QCJA 5GTJA 1C88A 1YWFA 5BZZA 3S4OA 1ZCLA 1Q6TA 2M3VA 4WU3A 1U25A 1D5RA
chains in the Genus database with same CATH superfamily
3ZMPA 2JFHA 4WOHA 3ZL8A 5HDEA 2F6VA 2NV5A 4J51A 4D3PA 5IBSA 2VEWA 1YTSA 1GWZA 1PTTA 2BGEA 3PYZA 2Y2FA 2C46A 4GS0A 4NWFA 1PXHA 4OHEA 2I1YA 1T49A 4JNBA 2VEXA 2J16A 2J17A 1ZCKA 4HV4A 2UUOA 2P6XA 2HCMA 2HB1A 2I42A 2H4VA 2CNIA 2OC3A 2XPCA 1RPMA 2CMCA 3CM3A 1PTVA 1KAKA 1XXVA 1G1FA 2JFGA 4JMJA 5K25A 5KABA 1LYVA 1OHEA 1LQFA 1W7KA 3O4SA 4GRZA 4HRFA 4B04A 2GC6A 2HXPA 4OHLA 3RGQA 4PVGA 1Q6MA 4BUCA 3EZZA 3O5XA 3V0EA 3MOWA 1L8GA 2F00A 2G6ZA 4KYQA 2I4EA 5KADA 1ONZA 4WTYA 2Y67A 4H34A 1PA9A 2F6TA 1T4JA 4R30A 2I6IA 3D42A 1C83A 2SHPA 2NZ6A 1L8KA 2H02A 2OZ5A 2A8BA 4KYRA 4D3RA 1UAGA 4GE2A 2CFVA 4OHIA 4Y2EA 3UAGA 1QXKA 2BZLA 4GE5A 2GCBA 4QDIA 4NWGA 1PA1A 1YTNA 2QDMA 5J8RA 5MMZB 3BLTA 2AZRA 3V0HA 4ERCA 2CMBA 2H03A 1A5YA 3A5KA 1P31A 3CWEA 5KA4A 4UAGA 2F70A 5BUGA 2QBRA 1OESA 3EAXA 2B3OA 2UUPA 1SUGA 5K24A 4DGXA 1LARA 4WU2A 3F9AA 2BIJA 2VEVA 3SMEA 3F41A 3EMUA 5KACA 2DXPA 1Q6SA 3N0AA 2H04A 1I9SA 2Y66A 2AM2A 4RH5A 3V0GA 2CNFA 5AWXA 1GQYA 2VORA 1J6UA 1C86A 1G4US 2HNQA 3GXHA 2HC2A 2I3UA 2UAGA 2CNEA 5K9WA 1P3DA 3A5JA 1PYNA 2PQ5A 3ZM5A 4CVLA 2I75A 2I4HA 2IMGA 2VEUA 1ECVA 4NX8A 5A5FA 1EENA 1YGUA 2I6JA 3AWGA 3QCNA 1NL9A 5KAAA 1Q6PA 1OEUA 1Q6JA 4Z6BA 4I8NA 2Y68A 2Y96A 2WTZA 3I36A 3RGOA 2ZMMA 4KI9A 5KA2A 4ZIYA 2QDCA 2PI7A 4C12A 1O5ZA 3V0IA 1FGSA 4BJOA 3EU0A 2F6FA 3B7OA 2QBQA 3MMJA 3S3FA 2GC5A 2QBPA 2YDUA 1PH0A 2WGPA 3O4UA 4CVKA 3QCJA 4NNDA 3QCLA 2F6WA 2CJZA 4HJPA 1JLNA 1I9TA 2C7SA 5K9VA 1C87A 1MKPA 3ZV2A 2VTEA 1BZJA 3ZMQA 1JBWA 2CNHA 1X24A 2CM2A 1XXPA 2CNGA 2H4KA 1NZ7A 2QBSA 4BUBA 3QCDA 1OHDA 4RDDA 2PSZA 4GE6A 2PA5A 4GWFA 1W78A 1ZZWA 3PS5A 5BX1A 5LXQB 3QCKA 2RF6A 2XJAA 3S3EA 4JBCA 5A5EA 3S3KA 2I5XA 1JF7A 4H1OA 1KAVA 2BGDA 3QKPA 2X5OA 2Y1OA 2QCTA 1GQQA 1ZC0A 2B4SA 2I4GA 3QCCA 1U26A 5KA3A 4OHHA 1OEVA 3U96A 4RKKA 3F9BA 3BM8A 4C13A 3I80A 3ZM3A 2HY3A 2FJNA 2VOSA 4YAAA 4ZN5A 4R0SA 4GFUA 3NMEA 1PTYA 1PTUA 2VTDA 1FQ1A 2ESBA 2A3KA 4DGPA 2BV5A 2FH7A 4QAPA 3S3HA 2CM7A 1FPRA 1R6HA 4ZI4A 3D9CA 2J16B 5BZXA 4JMKA 3QCHA 3BLUA 3F99A 1XRIA 1GG4A 2F6YA 1OEMX 2Q05A 3QCEA 2CM8A 3SR9A 1VHRA 1WAXA 1V3AA 2B07A 2I6MA 4IKCA 4RHGA 2JFFA 1GFYA 3QCZA 3ZM1A 1G4WR 2PBNA 4GRYA 1C85A 3MVNA 4ZRTA 4RI4A 1E0DA 1YGRA 4PYHA 4TVVA 3RO1A 4D3QA 5KA1A 4QBWA 1QZ0A 2GJTA 5EHPA 2F71A 2B49A 3H2XA 2CM3A 1G1GA 5IBMA 2F46A 2PT0A 1Q1MA 3D1HA 4R0TA 1NWLA 4MBBA 2I6PA 1XM2A 1E8CA 1WRMA 1ONYA 2NT7A 1NNYA 2VEYA 2CMAA 3HN7A 3QKQA 2AHSA 2WJPA 4HJQA 1AAXA 2H4GA 5KA9A 2MBCA 4RI5A 3I7ZA 1OETA 3D1QA 2R0BA 5I6VA 1OHCA 5K23A 3O3LA 3QCFA 2HVLA 3EB1A 2GCAA 3M4UA 5M43A 4S0GA 1XBOA 4BPCA 1EEHA 1P15A 1OEOX 2I3RA 2E0TA 4QAHA 3QCBA 2G59A 4Y14A 3V0FA 1Q6NA 3D44A 2B4PA 2B4UA 1FPZA 2B4OA 1J4XA 4QF5A 5KA7A 3ZM2A 2ZN7A 1RXDA 4RH9A 5EHRA 2HC1A 3BRHA 2FJMA 2OOQA 4QUNA 2GP0A 5K22A 1M3GA 2QEPA 1JBVA 4ICZA 2QDPA 2P4DA 2AM1A 5KA8A 2OUDA 4OHDA 3V0DA 1C84A 1NWEA 3OLRA 1YFOA 3S4EA 3QCGA 3RZ2A 4CVMA 4YR8B 1G7FA 3LJ8A 3QCIA 3AWFA 1EEOA 1YTWA 3ZM6A 2GWOA 2NT2A 2Q47A 3D1OA 1BZHA 5KA0A 3GXGA 2NTAA 3QCMA 2JJDA 3O4TA 4GFVA 1T48A 1U24A 1BZCA 3ZM0A 1NO6A 4QBEA 1YZ4A 1WCHA 1YPTA 3F81A 2HNPA 1G7GA 2F6ZA 3OMHA 4QUMA 2I6OA 3V0JA 3AWEA 1YN9A 2NLKA 3MOZA 1I57A 4AZ1A 1G1HA 4NYHA 2QCJA 3LK7A 5GTJA 3N2AA 1C88A 1YWFA 5BZZA 3S4OA 1ZCLA 1Q6TA 2M3VA 3NRSA 4WU3A 1U25A 1D5RA
chains in the Genus database with same CATH topology
3ZMPA 4WOHA 5HDEA 2F6VA 2NV5A 4J51A 4D3PA 5IBSA 2VEWA 1YTSA 1GWZA 1PTTA 2BGEA 2Y2FA 2C46A 4GS0A 4NWFA 1PXHA 4OHEA 2I1YA 1T49A 4JNBA 2VEXA 2J16A 2J17A 1ZCKA 2P6XA 2HCMA 2HB1A 2I42A 2H4VA 2CNIA 2OC3A 1RPMA 2CMCA 3CM3A 1PTVA 1KAKA 1XXVA 1G1FA 5K25A 4JMJA 5KABA 1LYVA 1OHEA 1LQFA 3O4SA 4GRZA 4HRFA 4B04A 2HXPA 4OHLA 3RGQA 4PVGA 1Q6MA 3EZZA 3O5XA 3V0EA 3MOWA 1L8GA 2G6ZA 4KYQA 2I4EA 5KADA 1ONZA 4WTYA 4H34A 1PA9A 2F6TA 1T4JA 4R30A 2I6IA 3D42A 1C83A 2SHPA 2NZ6A 1L8KA 2H02A 2OZ5A 2A8BA 4KYRA 4D3RA 4GE2A 2CFVA 4OHIA 4Y2EA 1QXKA 2BZLA 4GE5A 4NWGA 1PA1A 1YTNA 2QDMA 5J8RA 5MMZB 3BLTA 2AZRA 3V0HA 4ERCA 2CMBA 2H03A 1A5YA 3A5KA 3CWEA 5KA4A 2F70A 5BUGA 2QBRA 1OESA 3EAXA 2B3OA 1SUGA 5K24A 4DGXA 1LARA 4WU2A 3F9AA 2BIJA 2VEVA 3SMEA 3F41A 3EMUA 5KACA 2DXPA 1Q6SA 3N0AA 2H04A 1I9SA 4RH5A 3V0GA 2CNFA 5AWXA 1C86A 1G4US 2HNQA 3GXHA 2HC2A 2I3UA 2CNEA 5K9WA 3A5JA 1PYNA 2PQ5A 2I75A 2I4HA 2IMGA 2VEUA 1ECVA 4NX8A 1EENA 1YGUA 2I6JA 3AWGA 3QCNA 1NL9A 5KAAA 1Q6PA 1OEUA 1Q6JA 4Z6BA 4I8NA 2Y96A 3I36A 3RGOA 2ZMMA 4KI9A 5KA2A 2QDCA 2PI7A 3V0IA 4BJOA 3EU0A 2F6FA 3B7OA 2QBQA 3MMJA 3S3FA 2QBPA 2YDUA 1PH0A 2WGPA 3O4UA 3QCJA 4NNDA 3QCLA 2F6WA 2CJZA 4HJPA 1JLNA 1I9TA 2C7SA 5K9VA 1C87A 1MKPA 3ZV2A 1BZJA 3ZMQA 2CNHA 1X24A 2CM2A 1XXPA 2CNGA 2H4KA 1NZ7A 2QBSA 3QCDA 1OHDA 4RDDA 2PSZA 4GE6A 2PA5A 4GWFA 1ZZWA 3PS5A 5BX1A 5LXQB 3QCKA 2RF6A 3S3EA 4JBCA 3S3KA 2I5XA 1JF7A 4H1OA 1KAVA 2BGDA 3QKPA 2QCTA 1ZC0A 2B4SA 2I4GA 3QCCA 1U26A 5KA3A 4OHHA 1OEVA 3U96A 4RKKA 3F9BA 3BM8A 3I80A 3ZM3A 2HY3A 2FJNA 4YAAA 4ZN5A 4R0SA 4GFUA 3NMEA 1PTYA 1PTUA 1FQ1A 2ESBA 2A3KA 4DGPA 2BV5A 2FH7A 4QAPA 3S3HA 2CM7A 1FPRA 1R6HA 4ZI4A 3D9CA 2J16B 5BZXA 4JMKA 3QCHA 3BLUA 3F99A 1XRIA 2F6YA 1OEMX 2Q05A 3QCEA 2CM8A 3SR9A 1VHRA 1WAXA 1V3AA 2B07A 2I6MA 4IKCA 4RHGA 1GFYA 3ZM1A 1G4WR 2PBNA 4GRYA 1C85A 4ZRTA 4RI4A 1YGRA 4PYHA 4TVVA 3RO1A 4D3QA 5KA1A 4QBWA 1QZ0A 2GJTA 5EHPA 2F71A 2B49A 3H2XA 2CM3A 1G1GA 5IBMA 2F46A 2PT0A 1Q1MA 3D1HA 4R0TA 1NWLA 4MBBA 2I6PA 1XM2A 1WRMA 1ONYA 2NT7A 1NNYA 2VEYA 2CMAA 3QKQA 2AHSA 4HJQA 1AAXA 2H4GA 5KA9A 2MBCA 4RI5A 3I7ZA 1OETA 3D1QA 2R0BA 5I6VA 1OHCA 5K23A 3O3LA 3QCFA 2HVLA 3EB1A 3M4UA 5M43A 4S0GA 1XBOA 4BPCA 1P15A 2I3RA 1OEOX 2E0TA 4QAHA 3QCBA 2G59A 4Y14A 3V0FA 1Q6NA 3D44A 2B4PA 2B4UA 1FPZA 2B4OA 1J4XA 5KA7A 3ZM2A 2ZN7A 1RXDA 4RH9A 5EHRA 2HC1A 3BRHA 2FJMA 2OOQA 4QUNA 2GP0A 5K22A 1M3GA 2QEPA 4ICZA 2QDPA 2P4DA 5KA8A 2OUDA 4OHDA 3V0DA 1C84A 1NWEA 3OLRA 1YFOA 3S4EA 3QCGA 3RZ2A 4YR8B 1G7FA 3LJ8A 3QCIA 3AWFA 1EEOA 1YTWA 2GWOA 2NT2A 2Q47A 3D1OA 1BZHA 5KA0A 3GXGA 2NTAA 3QCMA 2JJDA 3O4TA 4GFVA 1T48A 1U24A 1BZCA 3ZM0A 1NO6A 4QBEA 1YZ4A 1WCHA 1YPTA 3F81A 2HNPA 1G7GA 2F6ZA 3OMHA 4QUMA 2I6OA 3V0JA 3AWEA 1YN9A 2NLKA 3MOZA 1I57A 4AZ1A 1G1HA 4NYHA 2QCJA 5GTJA 1C88A 1YWFA 5BZZA 3S4OA 1ZCLA 1Q6TA 2M3VA 4WU3A 1U25A 1D5RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZMP A;  4WOH A;  5HDE A;  2F6V A;  2NV5 A;  4J51 A;  4D3P A;  5IBS A;  2VEW A;  1YTS A;  1GWZ A;  1PTT A;  2BGE A;  2Y2F A;  2C46 A;  4GS0 A;  4NWF A;  1PXH A;  4OHE A;  2I1Y A;  1T49 A;  4JNB A;  2VEX A;  2J16 A;  2J17 A;  1ZCK A;  2P6X A;  2HCM A;  2HB1 A;  2I42 A;  2H4V A;  2CNI A;  2OC3 A;  1RPM A;  2CMC A;  3CM3 A;  1PTV A;  1KAK A;  1XXV A;  1G1F A;  5K25 A;  4JMJ A;  5KAB A;  1LYV A;  1OHE A;  1LQF A;  3O4S A;  4GRZ A;  4HRF A;  4B04 A;  2HXP A;  4OHL A;  3RGQ A;  4PVG A;  1Q6M A;  3EZZ A;  3O5X A;  3V0E A;  3MOW A;  1L8G A;  2G6Z A;  4KYQ A;  2I4E A;  5KAD A;  1ONZ A;  4WTY A;  4H34 A;  1PA9 A;  2F6T A;  1T4J A;  4R30 A;  2I6I A;  3D42 A;  1C83 A;  2SHP A;  2NZ6 A;  1L8K A;  2H02 A;  2OZ5 A;  2A8B A;  4KYR A;  4D3R A;  4GE2 A;  2CFV A;  4OHI A;  4Y2E A;  1QXK A;  2BZL A;  4GE5 A;  4NWG A;  1PA1 A;  1YTN A;  2QDM A;  5J8R A;  5MMZ B;  3BLT A;  2AZR A;  3V0H A;  4ERC A;  2CMB A;  2H03 A;  1A5Y A;  3A5K A;  3CWE A;  5KA4 A;  2F70 A;  5BUG A;  2QBR A;  1OES A;  3EAX A;  2B3O A;  1SUG A;  5K24 A;  4DGX A;  1LAR A;  4WU2 A;  3F9A A;  2BIJ A;  2VEV A;  3SME A;  3F41 A;  3EMU A;  5KAC A;  2DXP A;  1Q6S A;  3N0A A;  2H04 A;  1I9S A;  4RH5 A;  3V0G A;  2CNF A;  5AWX A;  1C86 A;  1G4U S;  2HNQ A;  3GXH A;  2HC2 A;  2I3U A;  2CNE A;  5K9W A;  3A5J A;  1PYN A;  2PQ5 A;  2I75 A;  2I4H A;  2IMG A;  2VEU A;  1ECV A;  4NX8 A;  1EEN A;  1YGU A;  2I6J A;  3AWG A;  3QCN A;  1NL9 A;  5KAA A;  1Q6P A;  1OEU A;  1Q6J A;  4Z6B A;  4I8N A;  2Y96 A;  3I36 A;  3RGO A;  2ZMM A;  4KI9 A;  5KA2 A;  2QDC A;  2PI7 A;  3V0I A;  4BJO A;  3EU0 A;  2F6F A;  3B7O A;  2QBQ A;  3MMJ A;  3S3F A;  2QBP A;  2YDU A;  1PH0 A;  2WGP A;  3O4U A;  3QCJ A;  4NND A;  3QCL A;  2F6W A;  2CJZ A;  4HJP A;  1JLN A;  1I9T A;  2C7S A;  5K9V A;  1C87 A;  1MKP A;  3ZV2 A;  1BZJ A;  3ZMQ A;  2CNH A;  1X24 A;  2CM2 A;  1XXP A;  2CNG A;  2H4K A;  1NZ7 A;  2QBS A;  3QCD A;  1OHD A;  4RDD A;  2PSZ A;  4GE6 A;  2PA5 A;  4GWF A;  1ZZW A;  3PS5 A;  5BX1 A;  5LXQ B;  3QCK A;  2RF6 A;  3S3E A;  4JBC A;  3S3K A;  2I5X A;  1JF7 A;  4H1O A;  1KAV A;  2BGD A;  3QKP A;  2QCT A;  1ZC0 A;  2B4S A;  2I4G A;  3QCC A;  1U26 A;  5KA3 A;  4OHH A;  1OEV A;  3U96 A;  4RKK A;  3F9B A;  3BM8 A;  3I80 A;  3ZM3 A;  2HY3 A;  2FJN A;  4YAA A;  4ZN5 A;  4R0S A;  4GFU A;  3NME A;  1PTY A;  1PTU A;  1FQ1 A;  2ESB A;  2A3K A;  4DGP A;  2BV5 A;  2FH7 A;  4QAP A;  3S3H A;  2CM7 A;  1FPR A;  1R6H A;  4ZI4 A;  3D9C A;  2J16 B;  5BZX A;  4JMK A;  3QCH A;  3BLU A;  3F99 A;  1XRI A;  2F6Y A;  1OEM X;  2Q05 A;  3QCE A;  2CM8 A;  3SR9 A;  1VHR A;  1WAX A;  1V3A A;  2B07 A;  2I6M A;  4IKC A;  4RHG A;  1GFY A;  3ZM1 A;  1G4W R;  2PBN A;  4GRY A;  1C85 A;  4ZRT A;  4RI4 A;  1YGR A;  4PYH A;  4TVV A;  3RO1 A;  4D3Q A;  5KA1 A;  4QBW A;  1QZ0 A;  2GJT A;  5EHP A;  2F71 A;  2B49 A;  3H2X A;  2CM3 A;  1G1G A;  5IBM A;  2F46 A;  2PT0 A;  1Q1M A;  3D1H A;  4R0T A;  1NWL A;  4MBB A;  2I6P A;  1XM2 A;  1WRM A;  1ONY A;  2NT7 A;  1NNY A;  2VEY A;  2CMA A;  3QKQ A;  2AHS A;  4HJQ A;  1AAX A;  2H4G A;  5KA9 A;  2MBC A;  4RI5 A;  3I7Z A;  1OET A;  3D1Q A;  2R0B A;  5I6V A;  1OHC A;  5K23 A;  3O3L A;  3QCF A;  2HVL A;  3EB1 A;  3M4U A;  5M43 A;  4S0G A;  1XBO A;  4BPC A;  1P15 A;  2I3R A;  1OEO X;  2E0T A;  4QAH A;  3QCB A;  2G59 A;  4Y14 A;  3V0F A;  1Q6N A;  3D44 A;  2B4P A;  2B4U A;  1FPZ A;  2B4O A;  1J4X A;  5KA7 A;  3ZM2 A;  2ZN7 A;  1RXD A;  4RH9 A;  5EHR A;  2HC1 A;  3BRH A;  2FJM A;  2OOQ A;  4QUN A;  2GP0 A;  5K22 A;  1M3G A;  2QEP A;  4ICZ A;  2QDP A;  2P4D A;  5KA8 A;  2OUD A;  4OHD A;  3V0D A;  1C84 A;  1NWE A;  3OLR A;  1YFO A;  3S4E A;  3QCG A;  3RZ2 A;  4YR8 B;  1G7F A;  3LJ8 A;  3QCI A;  3AWF A;  1EEO A;  1YTW A;  2GWO A;  2NT2 A;  2Q47 A;  3D1O A;  1BZH A;  5KA0 A;  3GXG A;  2NTA A;  3QCM A;  2JJD A;  3O4T A;  4GFV A;  1T48 A;  1U24 A;  1BZC A;  3ZM0 A;  1NO6 A;  4QBE A;  1YZ4 A;  1WCH A;  1YPT A;  3F81 A;  2HNP A;  1G7G A;  2F6Z A;  3OMH A;  4QUM A;  2I6O A;  3V0J A;  3AWE A;  1YN9 A;  2NLK A;  3MOZ A;  1I57 A;  4AZ1 A;  1G1H A;  4NYH A;  2QCJ A;  5GTJ A;  1C88 A;  1YWF A;  5BZZ A;  3S4O A;  1ZCL A;  1Q6T A;  2M3V A;  4WU3 A;  1U25 A;  1D5R A; 
#chains in the Genus database with same CATH topology
 3ZMP A;  2JFH A;  4WOH A;  3ZL8 A;  5HDE A;  2F6V A;  2NV5 A;  4J51 A;  4D3P A;  5IBS A;  2VEW A;  1YTS A;  1GWZ A;  1PTT A;  2BGE A;  3PYZ A;  2Y2F A;  2C46 A;  4GS0 A;  4NWF A;  1PXH A;  4OHE A;  2I1Y A;  1T49 A;  4JNB A;  2VEX A;  2J16 A;  2J17 A;  1ZCK A;  4HV4 A;  2UUO A;  2P6X A;  2HCM A;  2HB1 A;  2I42 A;  2H4V A;  2CNI A;  2OC3 A;  2XPC A;  1RPM A;  2CMC A;  3CM3 A;  1PTV A;  1KAK A;  1XXV A;  1G1F A;  2JFG A;  4JMJ A;  5K25 A;  5KAB A;  1LYV A;  1OHE A;  1LQF A;  1W7K A;  3O4S A;  4GRZ A;  4HRF A;  4B04 A;  2GC6 A;  2HXP A;  4OHL A;  3RGQ A;  4PVG A;  1Q6M A;  4BUC A;  3EZZ A;  3O5X A;  3V0E A;  3MOW A;  1L8G A;  2F00 A;  2G6Z A;  4KYQ A;  2I4E A;  5KAD A;  1ONZ A;  4WTY A;  2Y67 A;  4H34 A;  1PA9 A;  2F6T A;  1T4J A;  4R30 A;  2I6I A;  3D42 A;  1C83 A;  2SHP A;  2NZ6 A;  1L8K A;  2H02 A;  2OZ5 A;  2A8B A;  4KYR A;  4D3R A;  1UAG A;  4GE2 A;  2CFV A;  4OHI A;  4Y2E A;  3UAG A;  1QXK A;  2BZL A;  4GE5 A;  2GCB A;  4QDI A;  4NWG A;  1PA1 A;  1YTN A;  2QDM A;  5J8R A;  5MMZ B;  3BLT A;  2AZR A;  3V0H A;  4ERC A;  2CMB A;  2H03 A;  1A5Y A;  3A5K A;  1P31 A;  3CWE A;  5KA4 A;  4UAG A;  2F70 A;  5BUG A;  2QBR A;  1OES A;  3EAX A;  2B3O A;  2UUP A;  1SUG A;  5K24 A;  4DGX A;  1LAR A;  4WU2 A;  3F9A A;  2BIJ A;  2VEV A;  3SME A;  3F41 A;  3EMU A;  5KAC A;  2DXP A;  1Q6S A;  3N0A A;  2H04 A;  1I9S A;  2Y66 A;  2AM2 A;  4RH5 A;  3V0G A;  2CNF A;  5AWX A;  1GQY A;  2VOR A;  1J6U A;  1C86 A;  1G4U S;  2HNQ A;  3GXH A;  2HC2 A;  2I3U A;  2UAG A;  2CNE A;  5K9W A;  1P3D A;  3A5J A;  1PYN A;  2PQ5 A;  3ZM5 A;  4CVL A;  2I75 A;  2I4H A;  2IMG A;  2VEU A;  1ECV A;  4NX8 A;  5A5F A;  1EEN A;  1YGU A;  2I6J A;  3AWG A;  3QCN A;  1NL9 A;  5KAA A;  1Q6P A;  1OEU A;  1Q6J A;  4Z6B A;  4I8N A;  2Y68 A;  2Y96 A;  2WTZ A;  3I36 A;  3RGO A;  2ZMM A;  4KI9 A;  5KA2 A;  4ZIY A;  2QDC A;  2PI7 A;  4C12 A;  1O5Z A;  3V0I A;  1FGS A;  4BJO A;  3EU0 A;  2F6F A;  3B7O A;  2QBQ A;  3MMJ A;  3S3F A;  2GC5 A;  2QBP A;  2YDU A;  1PH0 A;  2WGP A;  3O4U A;  4CVK A;  3QCJ A;  4NND A;  3QCL A;  2F6W A;  2CJZ A;  4HJP A;  1JLN A;  1I9T A;  2C7S A;  5K9V A;  1C87 A;  1MKP A;  3ZV2 A;  2VTE A;  1BZJ A;  3ZMQ A;  1JBW A;  2CNH A;  1X24 A;  2CM2 A;  1XXP A;  2CNG A;  2H4K A;  1NZ7 A;  2QBS A;  4BUB A;  3QCD A;  1OHD A;  4RDD A;  2PSZ A;  4GE6 A;  2PA5 A;  4GWF A;  1W78 A;  1ZZW A;  3PS5 A;  5BX1 A;  5LXQ B;  3QCK A;  2RF6 A;  2XJA A;  3S3E A;  4JBC A;  5A5E A;  3S3K A;  2I5X A;  1JF7 A;  4H1O A;  1KAV A;  2BGD A;  3QKP A;  2X5O A;  2Y1O A;  2QCT A;  1GQQ A;  1ZC0 A;  2B4S A;  2I4G A;  3QCC A;  1U26 A;  5KA3 A;  4OHH A;  1OEV A;  3U96 A;  4RKK A;  3F9B A;  3BM8 A;  4C13 A;  3I80 A;  3ZM3 A;  2HY3 A;  2FJN A;  2VOS A;  4YAA A;  4ZN5 A;  4R0S A;  4GFU A;  3NME A;  1PTY A;  1PTU A;  2VTD A;  1FQ1 A;  2ESB A;  2A3K A;  4DGP A;  2BV5 A;  2FH7 A;  4QAP A;  3S3H A;  2CM7 A;  1FPR A;  1R6H A;  4ZI4 A;  3D9C A;  2J16 B;  5BZX A;  4JMK A;  3QCH A;  3BLU A;  3F99 A;  1XRI A;  1GG4 A;  2F6Y A;  1OEM X;  2Q05 A;  3QCE A;  2CM8 A;  3SR9 A;  1VHR A;  1WAX A;  1V3A A;  2B07 A;  2I6M A;  4IKC A;  4RHG A;  2JFF A;  1GFY A;  3QCZ A;  3ZM1 A;  1G4W R;  2PBN A;  4GRY A;  1C85 A;  3MVN A;  4ZRT A;  4RI4 A;  1E0D A;  1YGR A;  4PYH A;  4TVV A;  3RO1 A;  4D3Q A;  5KA1 A;  4QBW A;  1QZ0 A;  2GJT A;  5EHP A;  2F71 A;  2B49 A;  3H2X A;  2CM3 A;  1G1G A;  5IBM A;  2F46 A;  2PT0 A;  1Q1M A;  3D1H A;  4R0T A;  1NWL A;  4MBB A;  2I6P A;  1XM2 A;  1E8C A;  1WRM A;  1ONY A;  2NT7 A;  1NNY A;  2VEY A;  2CMA A;  3HN7 A;  3QKQ A;  2AHS A;  2WJP A;  4HJQ A;  1AAX A;  2H4G A;  5KA9 A;  2MBC A;  4RI5 A;  3I7Z A;  1OET A;  3D1Q A;  2R0B A;  5I6V A;  1OHC A;  5K23 A;  3O3L A;  3QCF A;  2HVL A;  3EB1 A;  2GCA A;  3M4U A;  5M43 A;  4S0G A;  1XBO A;  4BPC A;  1EEH A;  1P15 A;  1OEO X;  2I3R A;  2E0T A;  4QAH A;  3QCB A;  2G59 A;  4Y14 A;  3V0F A;  1Q6N A;  3D44 A;  2B4P A;  2B4U A;  1FPZ A;  2B4O A;  1J4X A;  4QF5 A;  5KA7 A;  3ZM2 A;  2ZN7 A;  1RXD A;  4RH9 A;  5EHR A;  2HC1 A;  3BRH A;  2FJM A;  2OOQ A;  4QUN A;  2GP0 A;  5K22 A;  1M3G A;  2QEP A;  1JBV A;  4ICZ A;  2QDP A;  2P4D A;  2AM1 A;  5KA8 A;  2OUD A;  4OHD A;  3V0D A;  1C84 A;  1NWE A;  3OLR A;  1YFO A;  3S4E A;  3QCG A;  3RZ2 A;  4CVM A;  4YR8 B;  1G7F A;  3LJ8 A;  3QCI A;  3AWF A;  1EEO A;  1YTW A;  3ZM6 A;  2GWO A;  2NT2 A;  2Q47 A;  3D1O A;  1BZH A;  5KA0 A;  3GXG A;  2NTA A;  3QCM A;  2JJD A;  3O4T A;  4GFV A;  1T48 A;  1U24 A;  1BZC A;  3ZM0 A;  1NO6 A;  4QBE A;  1YZ4 A;  1WCH A;  1YPT A;  3F81 A;  2HNP A;  1G7G A;  2F6Z A;  3OMH A;  4QUM A;  2I6O A;  3V0J A;  3AWE A;  1YN9 A;  2NLK A;  3MOZ A;  1I57 A;  4AZ1 A;  1G1H A;  4NYH A;  2QCJ A;  3LK7 A;  5GTJ A;  3N2A A;  1C88 A;  1YWF A;  5BZZ A;  3S4O A;  1ZCL A;  1Q6T A;  2M3V A;  3NRS A;  4WU3 A;  1U25 A;  1D5R A; 
#chains in the Genus database with same CATH homology
 3ZMP A;  4WOH A;  5HDE A;  2F6V A;  2NV5 A;  4J51 A;  4D3P A;  5IBS A;  2VEW A;  1YTS A;  1GWZ A;  1PTT A;  2BGE A;  2Y2F A;  2C46 A;  4GS0 A;  4NWF A;  1PXH A;  4OHE A;  2I1Y A;  1T49 A;  4JNB A;  2VEX A;  2J16 A;  2J17 A;  1ZCK A;  2P6X A;  2HCM A;  2HB1 A;  2I42 A;  2H4V A;  2CNI A;  2OC3 A;  1RPM A;  2CMC A;  3CM3 A;  1PTV A;  1KAK A;  1XXV A;  1G1F A;  5K25 A;  4JMJ A;  5KAB A;  1LYV A;  1OHE A;  1LQF A;  3O4S A;  4GRZ A;  4HRF A;  4B04 A;  2HXP A;  4OHL A;  3RGQ A;  4PVG A;  1Q6M A;  3EZZ A;  3O5X A;  3V0E A;  3MOW A;  1L8G A;  2G6Z A;  4KYQ A;  2I4E A;  5KAD A;  1ONZ A;  4WTY A;  4H34 A;  1PA9 A;  2F6T A;  1T4J A;  4R30 A;  2I6I A;  3D42 A;  1C83 A;  2SHP A;  2NZ6 A;  1L8K A;  2H02 A;  2OZ5 A;  2A8B A;  4KYR A;  4D3R A;  4GE2 A;  2CFV A;  4OHI A;  4Y2E A;  1QXK A;  2BZL A;  4GE5 A;  4NWG A;  1PA1 A;  1YTN A;  2QDM A;  5J8R A;  5MMZ B;  3BLT A;  2AZR A;  3V0H A;  4ERC A;  2CMB A;  2H03 A;  1A5Y A;  3A5K A;  3CWE A;  5KA4 A;  2F70 A;  5BUG A;  2QBR A;  1OES A;  3EAX A;  2B3O A;  1SUG A;  5K24 A;  4DGX A;  1LAR A;  4WU2 A;  3F9A A;  2BIJ A;  2VEV A;  3SME A;  3F41 A;  3EMU A;  5KAC A;  2DXP A;  1Q6S A;  3N0A A;  2H04 A;  1I9S A;  4RH5 A;  3V0G A;  2CNF A;  5AWX A;  1C86 A;  1G4U S;  2HNQ A;  3GXH A;  2HC2 A;  2I3U A;  2CNE A;  5K9W A;  3A5J A;  1PYN A;  2PQ5 A;  2I75 A;  2I4H A;  2IMG A;  2VEU A;  1ECV A;  4NX8 A;  1EEN A;  1YGU A;  2I6J A;  3AWG A;  3QCN A;  1NL9 A;  5KAA A;  1Q6P A;  1OEU A;  1Q6J A;  4Z6B A;  4I8N A;  2Y96 A;  3I36 A;  3RGO A;  2ZMM A;  4KI9 A;  5KA2 A;  2QDC A;  2PI7 A;  3V0I A;  4BJO A;  3EU0 A;  2F6F A;  3B7O A;  2QBQ A;  3MMJ A;  3S3F A;  2QBP A;  2YDU A;  1PH0 A;  2WGP A;  3O4U A;  3QCJ A;  4NND A;  3QCL A;  2F6W A;  2CJZ A;  4HJP A;  1JLN A;  1I9T A;  2C7S A;  5K9V A;  1C87 A;  1MKP A;  3ZV2 A;  1BZJ A;  3ZMQ A;  2CNH A;  1X24 A;  2CM2 A;  1XXP A;  2CNG A;  2H4K A;  1NZ7 A;  2QBS A;  3QCD A;  1OHD A;  4RDD A;  2PSZ A;  4GE6 A;  2PA5 A;  4GWF A;  1ZZW A;  3PS5 A;  5BX1 A;  5LXQ B;  3QCK A;  2RF6 A;  3S3E A;  4JBC A;  3S3K A;  2I5X A;  1JF7 A;  4H1O A;  1KAV A;  2BGD A;  3QKP A;  2QCT A;  1ZC0 A;  2B4S A;  2I4G A;  3QCC A;  1U26 A;  5KA3 A;  4OHH A;  1OEV A;  3U96 A;  4RKK A;  3F9B A;  3BM8 A;  3I80 A;  3ZM3 A;  2HY3 A;  2FJN A;  4YAA A;  4ZN5 A;  4R0S A;  4GFU A;  3NME A;  1PTY A;  1PTU A;  1FQ1 A;  2ESB A;  2A3K A;  4DGP A;  2BV5 A;  2FH7 A;  4QAP A;  3S3H A;  2CM7 A;  1FPR A;  1R6H A;  4ZI4 A;  3D9C A;  2J16 B;  5BZX A;  4JMK A;  3QCH A;  3BLU A;  3F99 A;  1XRI A;  2F6Y A;  1OEM X;  2Q05 A;  3QCE A;  2CM8 A;  3SR9 A;  1VHR A;  1WAX A;  1V3A A;  2B07 A;  2I6M A;  4IKC A;  4RHG A;  1GFY A;  3ZM1 A;  1G4W R;  2PBN A;  4GRY A;  1C85 A;  4ZRT A;  4RI4 A;  1YGR A;  4PYH A;  4TVV A;  3RO1 A;  4D3Q A;  5KA1 A;  4QBW A;  1QZ0 A;  2GJT A;  5EHP A;  2F71 A;  2B49 A;  3H2X A;  2CM3 A;  1G1G A;  5IBM A;  2F46 A;  2PT0 A;  1Q1M A;  3D1H A;  4R0T A;  1NWL A;  4MBB A;  2I6P A;  1XM2 A;  1WRM A;  1ONY A;  2NT7 A;  1NNY A;  2VEY A;  2CMA A;  3QKQ A;  2AHS A;  4HJQ A;  1AAX A;  2H4G A;  5KA9 A;  2MBC A;  4RI5 A;  3I7Z A;  1OET A;  3D1Q A;  2R0B A;  5I6V A;  1OHC A;  5K23 A;  3O3L A;  3QCF A;  2HVL A;  3EB1 A;  3M4U A;  5M43 A;  4S0G A;  1XBO A;  4BPC A;  1P15 A;  2I3R A;  1OEO X;  2E0T A;  4QAH A;  3QCB A;  2G59 A;  4Y14 A;  3V0F A;  1Q6N A;  3D44 A;  2B4P A;  2B4U A;  1FPZ A;  2B4O A;  1J4X A;  5KA7 A;  3ZM2 A;  2ZN7 A;  1RXD A;  4RH9 A;  5EHR A;  2HC1 A;  3BRH A;  2FJM A;  2OOQ A;  4QUN A;  2GP0 A;  5K22 A;  1M3G A;  2QEP A;  4ICZ A;  2QDP A;  2P4D A;  5KA8 A;  2OUD A;  4OHD A;  3V0D A;  1C84 A;  1NWE A;  3OLR A;  1YFO A;  3S4E A;  3QCG A;  3RZ2 A;  4YR8 B;  1G7F A;  3LJ8 A;  3QCI A;  3AWF A;  1EEO A;  1YTW A;  2GWO A;  2NT2 A;  2Q47 A;  3D1O A;  1BZH A;  5KA0 A;  3GXG A;  2NTA A;  3QCM A;  2JJD A;  3O4T A;  4GFV A;  1T48 A;  1U24 A;  1BZC A;  3ZM0 A;  1NO6 A;  4QBE A;  1YZ4 A;  1WCH A;  1YPT A;  3F81 A;  2HNP A;  1G7G A;  2F6Z A;  3OMH A;  4QUM A;  2I6O A;  3V0J A;  3AWE A;  1YN9 A;  2NLK A;  3MOZ A;  1I57 A;  4AZ1 A;  1G1H A;  4NYH A;  2QCJ A;  5GTJ A;  1C88 A;  1YWF A;  5BZZ A;  3S4O A;  1ZCL A;  1Q6T A;  2M3V A;  4WU3 A;  1U25 A;  1D5R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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