5KA7A

Protein tyrosine phosphatase 1b t178a mutant in complex with tcs401, closed state
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
298
structure length
298
Chain Sequence
SMEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTAWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
total genus 109
structure length 298
sequence length 298
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2016-06-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 5ka7A00
1P15A 3RGOA 1C85A 5M43A 1GWZA 1YN9A 2J16A 1Q6NA 2E0TA 1L8GA 5GTJA 1M3GA 4OHEA 3RZ2A 4GRYA 1T48A 4ZN5A 2PBNA 4YAAA 1YTNA 3ZM3A 3MOWA 3EU0A 2JJDA 2I6MA 4GFUA 4TVVA 2I3UA 1RPMA 1YFOA 5EHRA 5I6VA 4OHLA 1G4WR 2GWOA 3F81A 1YGRA 2CFVA 1OHDA 1WAXA 2QBQA 1ZC0A 2I75A 4ZI4A 3BRHA 2QBPA 1U26A 4R0SA 3S3HA 5KA1A 3ZMQA 2QDCA 1D5RA 3QCJA 1OETA 2B3OA 4PVGA 4QAHA 2HCMA 2Y2FA 2HB1A 3CWEA 1L8KA 1R6HA 2QCJA 2J16B 5KAAA 5BZZA 2H04A 4OHIA 1EENA 2OOQA 4JNBA 2R0BA 4NYHA 1V3AA 2QCTA 1LYVA 2HXPA 3MMJA 2QDMA 1YTWA 2OZ5A 3S4OA 1YZ4A 2GP0A 2HVLA 5KA0A 3V0GA 1PTTA 2H4KA 2HY3A 2I5XA 1G7GA 1VHRA 4GRZA 1X24A 3SMEA 2A3KA 4WU2A 2IMGA 2G6ZA 2C7SA 4HJPA 3RO1A 4OHHA 3H2XA 2PQ5A 3U96A 3QCMA 2NLKA 1C88A 1AAXA 1OEMX 3RGQA 2I1YA 3B7OA 2CM2A 3I7ZA 3GXHA 1ZCLA 2CMAA 2NT7A 3ZM0A 4D3QA 3BLUA 4QBWA 4GFVA 3F9AA 4HJQA 1G7FA 4NWFA 2CM8A 5K23A 1FPRA 1Q6TA 2I6OA 1MKPA 1SUGA 5KADA 4KYQA 3PS5A 1BZCA 3F99A 2HC1A 2I4GA 3AWEA 5HDEA 4BJOA 1NL9A 2NT2A 2AZRA 1OEUA 3GXGA 2H02A 1ZZWA 2F6WA 5K24A 2C46A 1EEOA 2F46A 5KA8A 2QBRA 3O5XA 5K9WA 1T4JA 2BIJA 1YPTA 2PSZA 2F6YA 3OLRA 5KA7A 5EHPA 5K25A 2OC3A 3ZM1A 3I80A 4R0TA 4KI9A 1OHCA 1XM2A 4RDDA 4DGPA 1PYNA 2NTAA 4JBCA 2DXPA 1T49A 3MOZA 2A8BA 5LXQB 4Z6BA 3D1HA 1J4XA 1XXPA 2I4EA 3SR9A 5BX1A 2VEXA 4ERCA 2H4GA 4ZRTA 2P6XA 3D1OA 1YWFA 4JMKA 2ZMMA 2FJNA 1XBOA 1PTYA 3AWGA 1NNYA 1PXHA 1PTVA 2QDPA 5KA2A 4Y14A 4RI4A 1C86A 2F70A 4AZ1A 2F6VA 4RH9A 1LQFA 1Q6MA 2QBSA 2ESBA 1G1HA 4RH5A 1XXVA 1PA1A 2CJZA 4H34A 1WRMA 1YTSA 2I42A 2AHSA 3EZZA 1NWLA 3QCCA 4HRFA 3N0AA 4WU3A 3V0IA 5KABA 3ZMPA 5KA3A 1C83A 3BM8A 3V0EA 4QUMA 2I6PA 5BZXA 2BGEA 2Q05A 2B49A 2PI7A 2F6TA 1PA9A 2B4OA 3QKPA 2VEWA 1NZ7A 2I6IA 1KAVA 3QKQA 2Y96A 5J8RA 3V0FA 2VEYA 2VEVA 1JLNA 1JF7A 4H1OA 3I36A 1BZHA 1FQ1A 3EAXA 3QCEA 4D3PA 1G1FA 5AWXA 4RKKA 2B07A 4B04A 4WOHA 3V0HA 1OHEA 1Q6JA 4S0GA 2VEUA 2F6ZA 2Q47A 2MBCA 3QCDA 2F71A 5IBSA 2FH7A 2B4PA 3EB1A 3O4TA 2G59A 3QCFA 1Q6SA 2H4VA 2I4HA 3QCKA 4OHDA 3O4SA 4DGXA 1QZ0A 1QXKA 2B4SA 3QCLA 4YR8B 3NMEA 2FJMA 1WCHA 2BV5A 1C84A 2HNPA 4J51A 4I8NA 2YDUA 3QCGA 3V0DA 3D1QA 2CNFA 1I9SA 5KA9A 4MBBA 1I57A 2PT0A 4GWFA 1OEVA 5KA4A 3OMHA 5BUGA 1C87A 4WTYA 2CM3A 4KYRA 4QBEA 4GE6A 4GE5A 2ZN7A 1ONYA 3EMUA 4JMJA 3M4UA 5K22A 1GFYA 2RF6A 2NV5A 2QEPA 2B4UA 3QCNA 1NWEA 2F6FA 4GE2A 1LARA 4BPCA 1Q1MA 2CMBA 3F41A 2CM7A 2BGDA 5IBMA 1ZCKA 1FPZA 1OEOX 4ICZA 2CNHA 3A5JA 3AWFA 1XRIA 4Y2EA 2CMCA 2GJTA 3S3KA 3S3EA 4IKCA 1PH0A 1G1GA 5K9VA 2HC2A 2CNEA 1G4US 1U24A 1OESA 3QCBA 4NWGA 1ECVA 4D3RA 4PYHA 4GS0A 3LJ8A 4QUNA 3BLTA 3D44A 1NO6A 4NX8A 3CM3A 1A5YA 3A5KA 2BZLA 2PA5A 3D42A 3D9CA 2HNQA 2I3RA 4RHGA 2NZ6A 1U25A 1RXDA 1I9TA 5KACA 1BZJA 5MMZB 2CNIA 4RI5A 3V0JA 2WGPA 2H03A 3F9BA 4NNDA 3QCHA 1YGUA 1Q6PA 4QAPA 3ZM2A 3O3LA 2I6JA 2J17A 3S4EA 3O4UA 1KAKA 1ONZA 2CNGA 3ZV2A 3S3FA 1PTUA 4R30A 2P4DA 2SHPA 3QCIA 2OUDA 2M3VA
chains in the Genus database with same CATH superfamily
1P15A 3RGOA 1C85A 5M43A 1GWZA 1YN9A 2J16A 1Q6NA 2E0TA 1L8GA 5GTJA 1M3GA 4OHEA 3RZ2A 4GRYA 1T48A 4ZN5A 2PBNA 4YAAA 1YTNA 3ZM3A 3MOWA 3EU0A 2JJDA 2I6MA 4GFUA 4TVVA 3UAGA 2I3UA 1RPMA 1YFOA 5EHRA 2GC6A 5I6VA 4OHLA 1G4WR 2GWOA 2GC5A 3F81A 1YGRA 2CFVA 1OHDA 1WAXA 2QBQA 1ZC0A 2I75A 1E0DA 4ZI4A 2GCAA 3BRHA 2F00A 2QBPA 1U26A 4R0SA 3S3HA 5KA1A 3ZMQA 2QDCA 4QDIA 1D5RA 3QCJA 1OETA 2B3OA 4CVKA 4PVGA 4QAHA 2HCMA 2Y2FA 2HB1A 1J6UA 3CWEA 1L8KA 1R6HA 2QCJA 2J16B 5KAAA 2X5OA 5BZZA 2H04A 4OHIA 3MVNA 1EENA 2OOQA 4JNBA 2R0BA 4NYHA 1V3AA 2QCTA 1LYVA 2HXPA 3MMJA 2QDMA 1YTWA 2OZ5A 3S4OA 1YZ4A 2Y1OA 2GP0A 2HVLA 5KA0A 3V0GA 1PTTA 2H4KA 2HY3A 2I5XA 1G7GA 1VHRA 4GRZA 1X24A 3SMEA 4C13A 2A3KA 4WU2A 2IMGA 2G6ZA 2C7SA 4HJPA 3RO1A 2Y68A 4OHHA 3H2XA 2PQ5A 3U96A 1P31A 3QCMA 2VORA 2NLKA 3ZM5A 1C88A 1AAXA 1OEMX 3RGQA 2I1YA 3B7OA 2CM2A 3I7ZA 2NT7A 1ZCLA 2CMAA 3GXHA 3ZM0A 4D3QA 3BLUA 4QBWA 4GFVA 3F9AA 4HJQA 1G7FA 4NWFA 2CM8A 5K23A 1FPRA 1UAGA 1Q6TA 2I6OA 1MKPA 1SUGA 5KADA 3ZL8A 4KYQA 3PS5A 1BZCA 2HC1A 2I4GA 3F99A 3AWEA 5HDEA 4BJOA 1NL9A 2NT2A 2AZRA 1OEUA 3GXGA 2H02A 1ZZWA 2F6WA 2Y67A 5K24A 2C46A 2VOSA 1EEOA 2F46A 5KA8A 2QBRA 3O5XA 5K9WA 1T4JA 1JBVA 2BIJA 1YPTA 2PSZA 2F6YA 3OLRA 5KA7A 5EHPA 5K25A 2OC3A 4BUCA 1P3DA 3ZM1A 3I80A 4R0TA 4KI9A 1OHCA 1XM2A 4RDDA 4DGPA 1PYNA 2NTAA 2UUOA 4JBCA 1O5ZA 2DXPA 1T49A 4C12A 3MOZA 2A8BA 5LXQB 4Z6BA 3D1HA 1J4XA 1XXPA 2I4EA 3SR9A 4QF5A 5BX1A 2VEXA 4ERCA 2H4GA 4ZRTA 2P6XA 2XJAA 3D1OA 1YWFA 2UUPA 1GG4A 4JMKA 2ZMMA 2FJNA 1XBOA 2WJPA 1PTYA 3AWGA 4HV4A 1NNYA 1PXHA 1PTVA 2JFHA 2QDPA 5KA2A 4Y14A 4RI4A 1C86A 2F70A 4AZ1A 2WTZA 2F6VA 4RH9A 1LQFA 1Q6MA 2QBSA 2ESBA 1G1HA 4RH5A 1XXVA 1PA1A 2CJZA 4H34A 1WRMA 1EEHA 1YTSA 2I42A 2AHSA 3EZZA 1NWLA 3QCCA 4HRFA 3N0AA 4WU3A 3V0IA 5KABA 3ZMPA 5KA3A 1C83A 2VTEA 3BM8A 1GQQA 1W7KA 3V0EA 4QUMA 2I6PA 5BZXA 2BGEA 2Q05A 2B49A 2PI7A 2F6TA 1PA9A 2B4OA 3QCZA 1FGSA 3HN7A 3QKPA 2VEWA 1NZ7A 2I6IA 1KAVA 3QKQA 2Y96A 5J8RA 3V0FA 2VEYA 2VEVA 1JLNA 1JBWA 1E8CA 1JF7A 4H1OA 3I36A 1BZHA 1FQ1A 3EAXA 3QCEA 4D3PA 1G1FA 5AWXA 4RKKA 2B07A 4B04A 3PYZA 4WOHA 3V0HA 1OHEA 1Q6JA 4S0GA 2VEUA 2F6ZA 2Q47A 2JFFA 2F71A 2MBCA 2AM1A 3QCDA 5IBSA 2FH7A 2B4PA 3EB1A 3O4TA 2G59A 3QCFA 1Q6SA 2H4VA 2I4HA 3QCKA 4OHDA 4ZIYA 3O4SA 2GCBA 4DGXA 1QZ0A 1QXKA 2B4SA 3QCLA 4YR8B 3NMEA 2FJMA 1WCHA 2BV5A 1C84A 2HNPA 4J51A 4I8NA 2YDUA 3QCGA 3V0DA 3D1QA 2CNFA 1I9SA 5KA9A 4MBBA 2JFGA 1I57A 2PT0A 3N2AA 4GWFA 1OEVA 5KA4A 3OMHA 5BUGA 1C87A 2XPCA 3ZM6A 4CVLA 4WTYA 2CM3A 4KYRA 4QBEA 4GE6A 4GE5A 2ZN7A 2UAGA 1ONYA 3EMUA 4JMJA 3M4UA 5K22A 1GFYA 2RF6A 2NV5A 2AM2A 2QEPA 2B4UA 3QCNA 1NWEA 2F6FA 4GE2A 1LARA 4BPCA 1Q1MA 2CMBA 3F41A 2CM7A 1W78A 1GQYA 2BGDA 5IBMA 1ZCKA 1FPZA 1OEOX 4ICZA 2CNHA 3A5JA 3AWFA 4CVMA 1XRIA 4Y2EA 2CMCA 2GJTA 3S3KA 3S3EA 4IKCA 1PH0A 1G1GA 5K9VA 2HC2A 4UAGA 2CNEA 1G4US 1U24A 1OESA 2VTDA 3QCBA 4NWGA 1ECVA 4D3RA 4PYHA 4GS0A 3LJ8A 4QUNA 3BLTA 3D44A 1NO6A 4NX8A 3CM3A 5A5FA 1A5YA 3A5KA 2BZLA 2PA5A 3D42A 3D9CA 3LK7A 2HNQA 2I3RA 4RHGA 2NZ6A 1U25A 1RXDA 2Y66A 1I9TA 5KACA 4BUBA 1BZJA 5MMZB 2CNIA 4RI5A 3V0JA 2WGPA 2H03A 3F9BA 4NNDA 3QCHA 1YGUA 1Q6PA 4QAPA 3ZM2A 3O3LA 2I6JA 2J17A 3S4EA 3O4UA 1KAKA 1ONZA 2CNGA 3NRSA 3ZV2A 3S3FA 1PTUA 4R30A 2P4DA 2SHPA 3QCIA 5A5EA 2OUDA 2M3VA
chains in the Genus database with same CATH topology
1P15A 3RGOA 1C85A 5M43A 1GWZA 1YN9A 2J16A 1Q6NA 2E0TA 1L8GA 5GTJA 1M3GA 4OHEA 3RZ2A 4GRYA 1T48A 4ZN5A 2PBNA 4YAAA 1YTNA 3ZM3A 3MOWA 3EU0A 2JJDA 2I6MA 4GFUA 4TVVA 2I3UA 1RPMA 1YFOA 5EHRA 5I6VA 4OHLA 1G4WR 2GWOA 3F81A 1YGRA 2CFVA 1OHDA 1WAXA 2QBQA 1ZC0A 2I75A 4ZI4A 3BRHA 2QBPA 1U26A 4R0SA 3S3HA 5KA1A 3ZMQA 2QDCA 1D5RA 3QCJA 1OETA 2B3OA 4PVGA 4QAHA 2HCMA 2Y2FA 2HB1A 3CWEA 1L8KA 1R6HA 2QCJA 2J16B 5KAAA 5BZZA 2H04A 4OHIA 1EENA 2OOQA 4JNBA 2R0BA 4NYHA 1V3AA 2QCTA 1LYVA 2HXPA 3MMJA 2QDMA 1YTWA 2OZ5A 3S4OA 1YZ4A 2GP0A 2HVLA 5KA0A 3V0GA 1PTTA 2H4KA 2HY3A 2I5XA 1G7GA 1VHRA 4GRZA 1X24A 3SMEA 2A3KA 4WU2A 2IMGA 2G6ZA 2C7SA 4HJPA 3RO1A 4OHHA 3H2XA 2PQ5A 3U96A 3QCMA 2NLKA 1C88A 1AAXA 1OEMX 3RGQA 2I1YA 3B7OA 2CM2A 3I7ZA 3GXHA 1ZCLA 2CMAA 2NT7A 3ZM0A 4D3QA 3BLUA 4QBWA 4GFVA 3F9AA 4HJQA 1G7FA 4NWFA 2CM8A 5K23A 1FPRA 1Q6TA 2I6OA 1MKPA 1SUGA 5KADA 4KYQA 3PS5A 1BZCA 3F99A 2HC1A 2I4GA 3AWEA 5HDEA 4BJOA 1NL9A 2NT2A 2AZRA 1OEUA 3GXGA 2H02A 1ZZWA 2F6WA 5K24A 2C46A 1EEOA 2F46A 5KA8A 2QBRA 3O5XA 5K9WA 1T4JA 2BIJA 1YPTA 2PSZA 2F6YA 3OLRA 5KA7A 5EHPA 5K25A 2OC3A 3ZM1A 3I80A 4R0TA 4KI9A 1OHCA 1XM2A 4RDDA 4DGPA 1PYNA 2NTAA 4JBCA 2DXPA 1T49A 3MOZA 2A8BA 5LXQB 4Z6BA 3D1HA 1J4XA 1XXPA 2I4EA 3SR9A 5BX1A 2VEXA 4ERCA 2H4GA 4ZRTA 2P6XA 3D1OA 1YWFA 4JMKA 2ZMMA 2FJNA 1XBOA 1PTYA 3AWGA 1NNYA 1PXHA 1PTVA 2QDPA 5KA2A 4Y14A 4RI4A 1C86A 2F70A 4AZ1A 2F6VA 4RH9A 1LQFA 1Q6MA 2QBSA 2ESBA 1G1HA 4RH5A 1XXVA 1PA1A 2CJZA 4H34A 1WRMA 1YTSA 2I42A 2AHSA 3EZZA 1NWLA 3QCCA 4HRFA 3N0AA 4WU3A 3V0IA 5KABA 3ZMPA 5KA3A 1C83A 3BM8A 3V0EA 4QUMA 2I6PA 5BZXA 2BGEA 2Q05A 2B49A 2PI7A 2F6TA 1PA9A 2B4OA 3QKPA 2VEWA 1NZ7A 2I6IA 1KAVA 3QKQA 2Y96A 5J8RA 3V0FA 2VEYA 2VEVA 1JLNA 1JF7A 4H1OA 3I36A 1BZHA 1FQ1A 3EAXA 3QCEA 4D3PA 1G1FA 5AWXA 4RKKA 2B07A 4B04A 4WOHA 3V0HA 1OHEA 1Q6JA 4S0GA 2VEUA 2F6ZA 2Q47A 2MBCA 3QCDA 2F71A 5IBSA 2FH7A 2B4PA 3EB1A 3O4TA 2G59A 3QCFA 1Q6SA 2H4VA 2I4HA 3QCKA 4OHDA 3O4SA 4DGXA 1QZ0A 1QXKA 2B4SA 3QCLA 4YR8B 3NMEA 2FJMA 1WCHA 2BV5A 1C84A 2HNPA 4J51A 4I8NA 2YDUA 3QCGA 3V0DA 3D1QA 2CNFA 1I9SA 5KA9A 4MBBA 1I57A 2PT0A 4GWFA 1OEVA 5KA4A 3OMHA 5BUGA 1C87A 4WTYA 2CM3A 4KYRA 4QBEA 4GE6A 4GE5A 2ZN7A 1ONYA 3EMUA 4JMJA 3M4UA 5K22A 1GFYA 2RF6A 2NV5A 2QEPA 2B4UA 3QCNA 1NWEA 2F6FA 4GE2A 1LARA 4BPCA 1Q1MA 2CMBA 3F41A 2CM7A 2BGDA 5IBMA 1ZCKA 1FPZA 1OEOX 4ICZA 2CNHA 3A5JA 3AWFA 1XRIA 4Y2EA 2CMCA 2GJTA 3S3KA 3S3EA 4IKCA 1PH0A 1G1GA 5K9VA 2HC2A 2CNEA 1G4US 1U24A 1OESA 3QCBA 4NWGA 1ECVA 4D3RA 4PYHA 4GS0A 3LJ8A 4QUNA 3BLTA 3D44A 1NO6A 4NX8A 3CM3A 1A5YA 3A5KA 2BZLA 2PA5A 3D42A 3D9CA 2HNQA 2I3RA 4RHGA 2NZ6A 1U25A 1RXDA 1I9TA 5KACA 1BZJA 5MMZB 2CNIA 4RI5A 3V0JA 2WGPA 2H03A 3F9BA 4NNDA 3QCHA 1YGUA 1Q6PA 4QAPA 3ZM2A 3O3LA 2I6JA 2J17A 3S4EA 3O4UA 1KAKA 1ONZA 2CNGA 3ZV2A 3S3FA 1PTUA 4R30A 2P4DA 2SHPA 3QCIA 2OUDA 2M3VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1P15 A;  3RGO A;  1C85 A;  5M43 A;  1GWZ A;  1YN9 A;  2J16 A;  1Q6N A;  2E0T A;  1L8G A;  5GTJ A;  1M3G A;  4OHE A;  3RZ2 A;  4GRY A;  1T48 A;  4ZN5 A;  2PBN A;  4YAA A;  1YTN A;  3ZM3 A;  3MOW A;  3EU0 A;  2JJD A;  2I6M A;  4GFU A;  4TVV A;  2I3U A;  1RPM A;  1YFO A;  5EHR A;  5I6V A;  4OHL A;  1G4W R;  2GWO A;  3F81 A;  1YGR A;  2CFV A;  1OHD A;  1WAX A;  2QBQ A;  1ZC0 A;  2I75 A;  4ZI4 A;  3BRH A;  2QBP A;  1U26 A;  4R0S A;  3S3H A;  5KA1 A;  3ZMQ A;  2QDC A;  1D5R A;  3QCJ A;  1OET A;  2B3O A;  4PVG A;  4QAH A;  2HCM A;  2Y2F A;  2HB1 A;  3CWE A;  1L8K A;  1R6H A;  2QCJ A;  2J16 B;  5KAA A;  5BZZ A;  2H04 A;  4OHI A;  1EEN A;  2OOQ A;  4JNB A;  2R0B A;  4NYH A;  1V3A A;  2QCT A;  1LYV A;  2HXP A;  3MMJ A;  2QDM A;  1YTW A;  2OZ5 A;  3S4O A;  1YZ4 A;  2GP0 A;  2HVL A;  5KA0 A;  3V0G A;  1PTT A;  2H4K A;  2HY3 A;  2I5X A;  1G7G A;  1VHR A;  4GRZ A;  1X24 A;  3SME A;  2A3K A;  4WU2 A;  2IMG A;  2G6Z A;  2C7S A;  4HJP A;  3RO1 A;  4OHH A;  3H2X A;  2PQ5 A;  3U96 A;  3QCM A;  2NLK A;  1C88 A;  1AAX A;  1OEM X;  3RGQ A;  2I1Y A;  3B7O A;  2CM2 A;  3I7Z A;  3GXH A;  1ZCL A;  2CMA A;  2NT7 A;  3ZM0 A;  4D3Q A;  3BLU A;  4QBW A;  4GFV A;  3F9A A;  4HJQ A;  1G7F A;  4NWF A;  2CM8 A;  5K23 A;  1FPR A;  1Q6T A;  2I6O A;  1MKP A;  1SUG A;  5KAD A;  4KYQ A;  3PS5 A;  1BZC A;  3F99 A;  2HC1 A;  2I4G A;  3AWE A;  5HDE A;  4BJO A;  1NL9 A;  2NT2 A;  2AZR A;  1OEU A;  3GXG A;  2H02 A;  1ZZW A;  2F6W A;  5K24 A;  2C46 A;  1EEO A;  2F46 A;  5KA8 A;  2QBR A;  3O5X A;  5K9W A;  1T4J A;  2BIJ A;  1YPT A;  2PSZ A;  2F6Y A;  3OLR A;  5KA7 A;  5EHP A;  5K25 A;  2OC3 A;  3ZM1 A;  3I80 A;  4R0T A;  4KI9 A;  1OHC A;  1XM2 A;  4RDD A;  4DGP A;  1PYN A;  2NTA A;  4JBC A;  2DXP A;  1T49 A;  3MOZ A;  2A8B A;  5LXQ B;  4Z6B A;  3D1H A;  1J4X A;  1XXP A;  2I4E A;  3SR9 A;  5BX1 A;  2VEX A;  4ERC A;  2H4G A;  4ZRT A;  2P6X A;  3D1O A;  1YWF A;  4JMK A;  2ZMM A;  2FJN A;  1XBO A;  1PTY A;  3AWG A;  1NNY A;  1PXH A;  1PTV A;  2QDP A;  5KA2 A;  4Y14 A;  4RI4 A;  1C86 A;  2F70 A;  4AZ1 A;  2F6V A;  4RH9 A;  1LQF A;  1Q6M A;  2QBS A;  2ESB A;  1G1H A;  4RH5 A;  1XXV A;  1PA1 A;  2CJZ A;  4H34 A;  1WRM A;  1YTS A;  2I42 A;  2AHS A;  3EZZ A;  1NWL A;  3QCC A;  4HRF A;  3N0A A;  4WU3 A;  3V0I A;  5KAB A;  3ZMP A;  5KA3 A;  1C83 A;  3BM8 A;  3V0E A;  4QUM A;  2I6P A;  5BZX A;  2BGE A;  2Q05 A;  2B49 A;  2PI7 A;  2F6T A;  1PA9 A;  2B4O A;  3QKP A;  2VEW A;  1NZ7 A;  2I6I A;  1KAV A;  3QKQ A;  2Y96 A;  5J8R A;  3V0F A;  2VEY A;  2VEV A;  1JLN A;  1JF7 A;  4H1O A;  3I36 A;  1BZH A;  1FQ1 A;  3EAX A;  3QCE A;  4D3P A;  1G1F A;  5AWX A;  4RKK A;  2B07 A;  4B04 A;  4WOH A;  3V0H A;  1OHE A;  1Q6J A;  4S0G A;  2VEU A;  2F6Z A;  2Q47 A;  2MBC A;  3QCD A;  2F71 A;  5IBS A;  2FH7 A;  2B4P A;  3EB1 A;  3O4T A;  2G59 A;  3QCF A;  1Q6S A;  2H4V A;  2I4H A;  3QCK A;  4OHD A;  3O4S A;  4DGX A;  1QZ0 A;  1QXK A;  2B4S A;  3QCL A;  4YR8 B;  3NME A;  2FJM A;  1WCH A;  2BV5 A;  1C84 A;  2HNP A;  4J51 A;  4I8N A;  2YDU A;  3QCG A;  3V0D A;  3D1Q A;  2CNF A;  1I9S A;  5KA9 A;  4MBB A;  1I57 A;  2PT0 A;  4GWF A;  1OEV A;  5KA4 A;  3OMH A;  5BUG A;  1C87 A;  4WTY A;  2CM3 A;  4KYR A;  4QBE A;  4GE6 A;  4GE5 A;  2ZN7 A;  1ONY A;  3EMU A;  4JMJ A;  3M4U A;  5K22 A;  1GFY A;  2RF6 A;  2NV5 A;  2QEP A;  2B4U A;  3QCN A;  1NWE A;  2F6F A;  4GE2 A;  1LAR A;  4BPC A;  1Q1M A;  2CMB A;  3F41 A;  2CM7 A;  2BGD A;  5IBM A;  1ZCK A;  1FPZ A;  1OEO X;  4ICZ A;  2CNH A;  3A5J A;  3AWF A;  1XRI A;  4Y2E A;  2CMC A;  2GJT A;  3S3K A;  3S3E A;  4IKC A;  1PH0 A;  1G1G A;  5K9V A;  2HC2 A;  2CNE A;  1G4U S;  1U24 A;  1OES A;  3QCB A;  4NWG A;  1ECV A;  4D3R A;  4PYH A;  4GS0 A;  3LJ8 A;  4QUN A;  3BLT A;  3D44 A;  1NO6 A;  4NX8 A;  3CM3 A;  1A5Y A;  3A5K A;  2BZL A;  2PA5 A;  3D42 A;  3D9C A;  2HNQ A;  2I3R A;  4RHG A;  2NZ6 A;  1U25 A;  1RXD A;  1I9T A;  5KAC A;  1BZJ A;  5MMZ B;  2CNI A;  4RI5 A;  3V0J A;  2WGP A;  2H03 A;  3F9B A;  4NND A;  3QCH A;  1YGU A;  1Q6P A;  4QAP A;  3ZM2 A;  3O3L A;  2I6J A;  2J17 A;  3S4E A;  3O4U A;  1KAK A;  1ONZ A;  2CNG A;  3ZV2 A;  3S3F A;  1PTU A;  4R30 A;  2P4D A;  2SHP A;  3QCI A;  2OUD A;  2M3V A; 
#chains in the Genus database with same CATH topology
 1P15 A;  3RGO A;  1C85 A;  5M43 A;  1GWZ A;  1YN9 A;  2J16 A;  1Q6N A;  2E0T A;  1L8G A;  5GTJ A;  1M3G A;  4OHE A;  3RZ2 A;  4GRY A;  1T48 A;  4ZN5 A;  2PBN A;  4YAA A;  1YTN A;  3ZM3 A;  3MOW A;  3EU0 A;  2JJD A;  2I6M A;  4GFU A;  4TVV A;  3UAG A;  2I3U A;  1RPM A;  1YFO A;  5EHR A;  2GC6 A;  5I6V A;  4OHL A;  1G4W R;  2GWO A;  2GC5 A;  3F81 A;  1YGR A;  2CFV A;  1OHD A;  1WAX A;  2QBQ A;  1ZC0 A;  2I75 A;  1E0D A;  4ZI4 A;  2GCA A;  3BRH A;  2F00 A;  2QBP A;  1U26 A;  4R0S A;  3S3H A;  5KA1 A;  3ZMQ A;  2QDC A;  4QDI A;  1D5R A;  3QCJ A;  1OET A;  2B3O A;  4CVK A;  4PVG A;  4QAH A;  2HCM A;  2Y2F A;  2HB1 A;  1J6U A;  3CWE A;  1L8K A;  1R6H A;  2QCJ A;  2J16 B;  5KAA A;  2X5O A;  5BZZ A;  2H04 A;  4OHI A;  3MVN A;  1EEN A;  2OOQ A;  4JNB A;  2R0B A;  4NYH A;  1V3A A;  2QCT A;  1LYV A;  2HXP A;  3MMJ A;  2QDM A;  1YTW A;  2OZ5 A;  3S4O A;  1YZ4 A;  2Y1O A;  2GP0 A;  2HVL A;  5KA0 A;  3V0G A;  1PTT A;  2H4K A;  2HY3 A;  2I5X A;  1G7G A;  1VHR A;  4GRZ A;  1X24 A;  3SME A;  4C13 A;  2A3K A;  4WU2 A;  2IMG A;  2G6Z A;  2C7S A;  4HJP A;  3RO1 A;  2Y68 A;  4OHH A;  3H2X A;  2PQ5 A;  3U96 A;  1P31 A;  3QCM A;  2VOR A;  2NLK A;  3ZM5 A;  1C88 A;  1AAX A;  1OEM X;  3RGQ A;  2I1Y A;  3B7O A;  2CM2 A;  3I7Z A;  2NT7 A;  1ZCL A;  2CMA A;  3GXH A;  3ZM0 A;  4D3Q A;  3BLU A;  4QBW A;  4GFV A;  3F9A A;  4HJQ A;  1G7F A;  4NWF A;  2CM8 A;  5K23 A;  1FPR A;  1UAG A;  1Q6T A;  2I6O A;  1MKP A;  1SUG A;  5KAD A;  3ZL8 A;  4KYQ A;  3PS5 A;  1BZC A;  2HC1 A;  2I4G A;  3F99 A;  3AWE A;  5HDE A;  4BJO A;  1NL9 A;  2NT2 A;  2AZR A;  1OEU A;  3GXG A;  2H02 A;  1ZZW A;  2F6W A;  2Y67 A;  5K24 A;  2C46 A;  2VOS A;  1EEO A;  2F46 A;  5KA8 A;  2QBR A;  3O5X A;  5K9W A;  1T4J A;  1JBV A;  2BIJ A;  1YPT A;  2PSZ A;  2F6Y A;  3OLR A;  5KA7 A;  5EHP A;  5K25 A;  2OC3 A;  4BUC A;  1P3D A;  3ZM1 A;  3I80 A;  4R0T A;  4KI9 A;  1OHC A;  1XM2 A;  4RDD A;  4DGP A;  1PYN A;  2NTA A;  2UUO A;  4JBC A;  1O5Z A;  2DXP A;  1T49 A;  4C12 A;  3MOZ A;  2A8B A;  5LXQ B;  4Z6B A;  3D1H A;  1J4X A;  1XXP A;  2I4E A;  3SR9 A;  4QF5 A;  5BX1 A;  2VEX A;  4ERC A;  2H4G A;  4ZRT A;  2P6X A;  2XJA A;  3D1O A;  1YWF A;  2UUP A;  1GG4 A;  4JMK A;  2ZMM A;  2FJN A;  1XBO A;  2WJP A;  1PTY A;  3AWG A;  4HV4 A;  1NNY A;  1PXH A;  1PTV A;  2JFH A;  2QDP A;  5KA2 A;  4Y14 A;  4RI4 A;  1C86 A;  2F70 A;  4AZ1 A;  2WTZ A;  2F6V A;  4RH9 A;  1LQF A;  1Q6M A;  2QBS A;  2ESB A;  1G1H A;  4RH5 A;  1XXV A;  1PA1 A;  2CJZ A;  4H34 A;  1WRM A;  1EEH A;  1YTS A;  2I42 A;  2AHS A;  3EZZ A;  1NWL A;  3QCC A;  4HRF A;  3N0A A;  4WU3 A;  3V0I A;  5KAB A;  3ZMP A;  5KA3 A;  1C83 A;  2VTE A;  3BM8 A;  1GQQ A;  1W7K A;  3V0E A;  4QUM A;  2I6P A;  5BZX A;  2BGE A;  2Q05 A;  2B49 A;  2PI7 A;  2F6T A;  1PA9 A;  2B4O A;  3QCZ A;  1FGS A;  3HN7 A;  3QKP A;  2VEW A;  1NZ7 A;  2I6I A;  1KAV A;  3QKQ A;  2Y96 A;  5J8R A;  3V0F A;  2VEY A;  2VEV A;  1JLN A;  1JBW A;  1E8C A;  1JF7 A;  4H1O A;  3I36 A;  1BZH A;  1FQ1 A;  3EAX A;  3QCE A;  4D3P A;  1G1F A;  5AWX A;  4RKK A;  2B07 A;  4B04 A;  3PYZ A;  4WOH A;  3V0H A;  1OHE A;  1Q6J A;  4S0G A;  2VEU A;  2F6Z A;  2Q47 A;  2JFF A;  2F71 A;  2MBC A;  2AM1 A;  3QCD A;  5IBS A;  2FH7 A;  2B4P A;  3EB1 A;  3O4T A;  2G59 A;  3QCF A;  1Q6S A;  2H4V A;  2I4H A;  3QCK A;  4OHD A;  4ZIY A;  3O4S A;  2GCB A;  4DGX A;  1QZ0 A;  1QXK A;  2B4S A;  3QCL A;  4YR8 B;  3NME A;  2FJM A;  1WCH A;  2BV5 A;  1C84 A;  2HNP A;  4J51 A;  4I8N A;  2YDU A;  3QCG A;  3V0D A;  3D1Q A;  2CNF A;  1I9S A;  5KA9 A;  4MBB A;  2JFG A;  1I57 A;  2PT0 A;  3N2A A;  4GWF A;  1OEV A;  5KA4 A;  3OMH A;  5BUG A;  1C87 A;  2XPC A;  3ZM6 A;  4CVL A;  4WTY A;  2CM3 A;  4KYR A;  4QBE A;  4GE6 A;  4GE5 A;  2ZN7 A;  2UAG A;  1ONY A;  3EMU A;  4JMJ A;  3M4U A;  5K22 A;  1GFY A;  2RF6 A;  2NV5 A;  2AM2 A;  2QEP A;  2B4U A;  3QCN A;  1NWE A;  2F6F A;  4GE2 A;  1LAR A;  4BPC A;  1Q1M A;  2CMB A;  3F41 A;  2CM7 A;  1W78 A;  1GQY A;  2BGD A;  5IBM A;  1ZCK A;  1FPZ A;  1OEO X;  4ICZ A;  2CNH A;  3A5J A;  3AWF A;  4CVM A;  1XRI A;  4Y2E A;  2CMC A;  2GJT A;  3S3K A;  3S3E A;  4IKC A;  1PH0 A;  1G1G A;  5K9V A;  2HC2 A;  4UAG A;  2CNE A;  1G4U S;  1U24 A;  1OES A;  2VTD A;  3QCB A;  4NWG A;  1ECV A;  4D3R A;  4PYH A;  4GS0 A;  3LJ8 A;  4QUN A;  3BLT A;  3D44 A;  1NO6 A;  4NX8 A;  3CM3 A;  5A5F A;  1A5Y A;  3A5K A;  2BZL A;  2PA5 A;  3D42 A;  3D9C A;  3LK7 A;  2HNQ A;  2I3R A;  4RHG A;  2NZ6 A;  1U25 A;  1RXD A;  2Y66 A;  1I9T A;  5KAC A;  4BUB A;  1BZJ A;  5MMZ B;  2CNI A;  4RI5 A;  3V0J A;  2WGP A;  2H03 A;  3F9B A;  4NND A;  3QCH A;  1YGU A;  1Q6P A;  4QAP A;  3ZM2 A;  3O3L A;  2I6J A;  2J17 A;  3S4E A;  3O4U A;  1KAK A;  1ONZ A;  2CNG A;  3NRS A;  3ZV2 A;  3S3F A;  1PTU A;  4R30 A;  2P4D A;  2SHP A;  3QCI A;  5A5E A;  2OUD A;  2M3V A; 
#chains in the Genus database with same CATH homology
 1P15 A;  3RGO A;  1C85 A;  5M43 A;  1GWZ A;  1YN9 A;  2J16 A;  1Q6N A;  2E0T A;  1L8G A;  5GTJ A;  1M3G A;  4OHE A;  3RZ2 A;  4GRY A;  1T48 A;  4ZN5 A;  2PBN A;  4YAA A;  1YTN A;  3ZM3 A;  3MOW A;  3EU0 A;  2JJD A;  2I6M A;  4GFU A;  4TVV A;  2I3U A;  1RPM A;  1YFO A;  5EHR A;  5I6V A;  4OHL A;  1G4W R;  2GWO A;  3F81 A;  1YGR A;  2CFV A;  1OHD A;  1WAX A;  2QBQ A;  1ZC0 A;  2I75 A;  4ZI4 A;  3BRH A;  2QBP A;  1U26 A;  4R0S A;  3S3H A;  5KA1 A;  3ZMQ A;  2QDC A;  1D5R A;  3QCJ A;  1OET A;  2B3O A;  4PVG A;  4QAH A;  2HCM A;  2Y2F A;  2HB1 A;  3CWE A;  1L8K A;  1R6H A;  2QCJ A;  2J16 B;  5KAA A;  5BZZ A;  2H04 A;  4OHI A;  1EEN A;  2OOQ A;  4JNB A;  2R0B A;  4NYH A;  1V3A A;  2QCT A;  1LYV A;  2HXP A;  3MMJ A;  2QDM A;  1YTW A;  2OZ5 A;  3S4O A;  1YZ4 A;  2GP0 A;  2HVL A;  5KA0 A;  3V0G A;  1PTT A;  2H4K A;  2HY3 A;  2I5X A;  1G7G A;  1VHR A;  4GRZ A;  1X24 A;  3SME A;  2A3K A;  4WU2 A;  2IMG A;  2G6Z A;  2C7S A;  4HJP A;  3RO1 A;  4OHH A;  3H2X A;  2PQ5 A;  3U96 A;  3QCM A;  2NLK A;  1C88 A;  1AAX A;  1OEM X;  3RGQ A;  2I1Y A;  3B7O A;  2CM2 A;  3I7Z A;  3GXH A;  1ZCL A;  2CMA A;  2NT7 A;  3ZM0 A;  4D3Q A;  3BLU A;  4QBW A;  4GFV A;  3F9A A;  4HJQ A;  1G7F A;  4NWF A;  2CM8 A;  5K23 A;  1FPR A;  1Q6T A;  2I6O A;  1MKP A;  1SUG A;  5KAD A;  4KYQ A;  3PS5 A;  1BZC A;  3F99 A;  2HC1 A;  2I4G A;  3AWE A;  5HDE A;  4BJO A;  1NL9 A;  2NT2 A;  2AZR A;  1OEU A;  3GXG A;  2H02 A;  1ZZW A;  2F6W A;  5K24 A;  2C46 A;  1EEO A;  2F46 A;  5KA8 A;  2QBR A;  3O5X A;  5K9W A;  1T4J A;  2BIJ A;  1YPT A;  2PSZ A;  2F6Y A;  3OLR A;  5KA7 A;  5EHP A;  5K25 A;  2OC3 A;  3ZM1 A;  3I80 A;  4R0T A;  4KI9 A;  1OHC A;  1XM2 A;  4RDD A;  4DGP A;  1PYN A;  2NTA A;  4JBC A;  2DXP A;  1T49 A;  3MOZ A;  2A8B A;  5LXQ B;  4Z6B A;  3D1H A;  1J4X A;  1XXP A;  2I4E A;  3SR9 A;  5BX1 A;  2VEX A;  4ERC A;  2H4G A;  4ZRT A;  2P6X A;  3D1O A;  1YWF A;  4JMK A;  2ZMM A;  2FJN A;  1XBO A;  1PTY A;  3AWG A;  1NNY A;  1PXH A;  1PTV A;  2QDP A;  5KA2 A;  4Y14 A;  4RI4 A;  1C86 A;  2F70 A;  4AZ1 A;  2F6V A;  4RH9 A;  1LQF A;  1Q6M A;  2QBS A;  2ESB A;  1G1H A;  4RH5 A;  1XXV A;  1PA1 A;  2CJZ A;  4H34 A;  1WRM A;  1YTS A;  2I42 A;  2AHS A;  3EZZ A;  1NWL A;  3QCC A;  4HRF A;  3N0A A;  4WU3 A;  3V0I A;  5KAB A;  3ZMP A;  5KA3 A;  1C83 A;  3BM8 A;  3V0E A;  4QUM A;  2I6P A;  5BZX A;  2BGE A;  2Q05 A;  2B49 A;  2PI7 A;  2F6T A;  1PA9 A;  2B4O A;  3QKP A;  2VEW A;  1NZ7 A;  2I6I A;  1KAV A;  3QKQ A;  2Y96 A;  5J8R A;  3V0F A;  2VEY A;  2VEV A;  1JLN A;  1JF7 A;  4H1O A;  3I36 A;  1BZH A;  1FQ1 A;  3EAX A;  3QCE A;  4D3P A;  1G1F A;  5AWX A;  4RKK A;  2B07 A;  4B04 A;  4WOH A;  3V0H A;  1OHE A;  1Q6J A;  4S0G A;  2VEU A;  2F6Z A;  2Q47 A;  2MBC A;  3QCD A;  2F71 A;  5IBS A;  2FH7 A;  2B4P A;  3EB1 A;  3O4T A;  2G59 A;  3QCF A;  1Q6S A;  2H4V A;  2I4H A;  3QCK A;  4OHD A;  3O4S A;  4DGX A;  1QZ0 A;  1QXK A;  2B4S A;  3QCL A;  4YR8 B;  3NME A;  2FJM A;  1WCH A;  2BV5 A;  1C84 A;  2HNP A;  4J51 A;  4I8N A;  2YDU A;  3QCG A;  3V0D A;  3D1Q A;  2CNF A;  1I9S A;  5KA9 A;  4MBB A;  1I57 A;  2PT0 A;  4GWF A;  1OEV A;  5KA4 A;  3OMH A;  5BUG A;  1C87 A;  4WTY A;  2CM3 A;  4KYR A;  4QBE A;  4GE6 A;  4GE5 A;  2ZN7 A;  1ONY A;  3EMU A;  4JMJ A;  3M4U A;  5K22 A;  1GFY A;  2RF6 A;  2NV5 A;  2QEP A;  2B4U A;  3QCN A;  1NWE A;  2F6F A;  4GE2 A;  1LAR A;  4BPC A;  1Q1M A;  2CMB A;  3F41 A;  2CM7 A;  2BGD A;  5IBM A;  1ZCK A;  1FPZ A;  1OEO X;  4ICZ A;  2CNH A;  3A5J A;  3AWF A;  1XRI A;  4Y2E A;  2CMC A;  2GJT A;  3S3K A;  3S3E A;  4IKC A;  1PH0 A;  1G1G A;  5K9V A;  2HC2 A;  2CNE A;  1G4U S;  1U24 A;  1OES A;  3QCB A;  4NWG A;  1ECV A;  4D3R A;  4PYH A;  4GS0 A;  3LJ8 A;  4QUN A;  3BLT A;  3D44 A;  1NO6 A;  4NX8 A;  3CM3 A;  1A5Y A;  3A5K A;  2BZL A;  2PA5 A;  3D42 A;  3D9C A;  2HNQ A;  2I3R A;  4RHG A;  2NZ6 A;  1U25 A;  1RXD A;  1I9T A;  5KAC A;  1BZJ A;  5MMZ B;  2CNI A;  4RI5 A;  3V0J A;  2WGP A;  2H03 A;  3F9B A;  4NND A;  3QCH A;  1YGU A;  1Q6P A;  4QAP A;  3ZM2 A;  3O3L A;  2I6J A;  2J17 A;  3S4E A;  3O4U A;  1KAK A;  1ONZ A;  2CNG A;  3ZV2 A;  3S3F A;  1PTU A;  4R30 A;  2P4D A;  2SHP A;  3QCI A;  2OUD A;  2M3V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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