5KA9A

Protein tyrosine phosphatase 1b l192a mutant in complex with tcs401, open state
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
299
structure length
299
Chain Sequence
GHMASMEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFANFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKEL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
total genus 106
structure length 299
sequence length 299
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2016-06-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 5ka9A00
2I5XA 5J8RA 1OEMX 2QEPA 1BZJA 2G59A 4WU2A 1XRIA 1L8KA 5EHPA 4NWFA 1L8GA 1QZ0A 4PVGA 1YFOA 3OMHA 2QDPA 1KAVA 2GJTA 1Q1MA 5LXQB 2FH7A 3I36A 2I4GA 1GWZA 2J17A 2F71A 2CMAA 1ZC0A 3V0GA 1OHCA 1PYNA 2I6IA 2GP0A 2Q05A 4ERCA 3BLTA 3ZV2A 4I8NA 1LQFA 2I42A 5IBMA 2B4PA 1M3GA 3ZMQA 2H03A 5EHRA 2F6YA 2ZMMA 1SUGA 2NT7A 2HC1A 4QBWA 2A3KA 3MOZA 3V0IA 2P4DA 2B3OA 2PI7A 4RH5A 2JJDA 1R6HA 1G1FA 3QCCA 1OEVA 3AWGA 4S0GA 4OHLA 1WRMA 4H34A 4HRFA 3U96A 3QCNA 2E0TA 2J16A 4MBBA 3RGQA 2ZN7A 3D9CA 4RDDA 2AHSA 2Q47A 4QBEA 3ZM2A 2QBQA 3F9AA 2NTAA 2SHPA 1YTSA 2HNQA 3QKPA 2CNEA 1G7GA 2QBSA 4IKCA 4NYHA 1AAXA 3I7ZA 4JMJA 5KABA 4JBCA 1YWFA 3F99A 1P15A 1PTTA 1T4JA 2C46A 3D42A 2CNIA 1EENA 2PA5A 1NWLA 1YN9A 2VEUA 4B04A 1I9SA 5BX1A 1QXKA 4Y2EA 2J16B 3EAXA 5KA4A 3RO1A 1U25A 2CM7A 1T48A 1WCHA 1T49A 3QCFA 2ESBA 2OZ5A 1Q6JA 2F6VA 4WTYA 2B49A 2F70A 1GFYA 3S3EA 2PSZA 5K24A 2CMCA 2BGEA 4QAPA 4RI5A 3O3LA 5K22A 2HB1A 3QCKA 2I6MA 4QUNA 1J4XA 1Q6MA 1C84A 3V0EA 4DGXA 2HVLA 1C88A 2AZRA 1OESA 3LJ8A 4OHHA 4R30A 3O4UA 5K9VA 3EZZA 1X24A 2QDCA 4PYHA 2DXPA 1BZCA 1PTVA 4NNDA 1C86A 1Q6PA 2B4UA 2I6JA 1G1HA 2F6ZA 4YAAA 4D3QA 5K9WA 2I4EA 2CNGA 2I3UA 3AWFA 2I1YA 3AWEA 1OHEA 3QCJA 4KI9A 5K23A 4JMKA 2H04A 1RXDA 3O4SA 1WAXA 1ZZWA 4OHIA 3H2XA 4QUMA 3V0DA 2CM3A 1NO6A 1G4US 4GS0A 4BJOA 3QCIA 2OC3A 3ZM3A 3BRHA 2HNPA 5KADA 5KAAA 1YTWA 3V0HA 1XXPA 4GFVA 1OETA 2NT2A 4GE6A 1YGUA 2G6ZA 2I6OA 2NZ6A 3QCDA 2NLKA 3O4TA 1U26A 2F6WA 1XXVA 4D3RA 1OHDA 3ZM1A 5GTJA 1ZCLA 1PA1A 3RZ2A 5KA0A 1A5YA 3MOWA 3S3FA 2CNHA 4R0TA 4KYRA 4Z6BA 2Y96A 4R0SA 1ZCKA 1NWEA 5BZXA 3F81A 4HJQA 2B4OA 5BZZA 1YZ4A 4GRZA 4OHDA 2C7SA 3EB1A 3B7OA 1PXHA 4H1OA 3O5XA 2A8BA 2I75A 2QDMA 4D3PA 3MMJA 3V0FA 2QBRA 1LYVA 2NV5A 3S3HA 4J51A 3NMEA 3D1QA 5MMZB 2FJNA 2M3VA 1C83A 4DGPA 2I4HA 3QCBA 3CWEA 3QCEA 2VEXA 2I6PA 5IBSA 3GXGA 1V3AA 3S4OA 1OEUA 5KACA 1XM2A 1I57A 3QCGA 3SMEA 4WU3A 3QCHA 4RHGA 1YPTA 3A5KA 4GE5A 3N0AA 4ZRTA 1PA9A 3D1HA 4NX8A 2QCTA 1MKPA 2PT0A 2CNFA 3CM3A 2H4GA 3QCLA 2P6XA 1D5RA 1C85A 4ICZA 4RH9A 2HY3A 2CJZA 3D44A 1G7FA 4YR8B 5KA9A 2B07A 1NZ7A 1FPZA 3V0JA 1Q6SA 2OUDA 1LARA 2F46A 1EEOA 4JNBA 2F6FA 3SR9A 3BLUA 4QAHA 2BIJA 1OEOX 1YGRA 2BGDA 1JLNA 4TVVA 1XBOA 3ZM0A 4ZN5A 2VEVA 1PTUA 5AWXA 3RGOA 1NL9A 2CM2A 3EU0A 1Q6TA 2MBCA 4OHEA 3ZMPA 4GWFA 2YDUA 3GXHA 4AZ1A 3S4EA 4GRYA 3S3KA 1JF7A 2FJMA 3F41A 1BZHA 5M43A 2VEYA 3QCMA 2QBPA 1G4WR 4RKKA 2Y2FA 3A5JA 5I6VA 1PTYA 2OOQA 1FQ1A 1NNYA 2CM8A 3F9BA 1YTNA 3D1OA 2PQ5A 2R0BA 1ECVA 1ONZA 3OLRA 2VEWA 1Q6NA 4Y14A 2HXPA 1FPRA 3M4UA 3PS5A 5HDEA 4KYQA 5BUGA 1C87A 5KA8A 5KA7A 1I9TA 4GE2A 4WOHA 3QKQA 1KAKA 1U24A 2CFVA 5K25A 2H02A 2GWOA 1VHRA 5KA2A 4RI4A 1RPMA 3I80A 2H4KA 2I3RA 5KA1A 2WGPA 3BM8A 2QCJA 2H4VA 1PH0A 2IMGA 2CMBA 2F6TA 2B4SA 2HC2A 2PBNA 2HCMA 4BPCA 3EMUA 4GFUA 2BV5A 2BZLA 4NWGA 1ONYA 2RF6A 4HJPA 4ZI4A 5KA3A 1G1GA
chains in the Genus database with same CATH superfamily
2GCAA 2I5XA 5J8RA 1OEMX 2QEPA 1BZJA 2G59A 4WU2A 1XRIA 1L8KA 5EHPA 2VOSA 4NWFA 1L8GA 1QZ0A 4PVGA 1YFOA 3OMHA 2QDPA 1KAVA 2AM2A 3NRSA 2GJTA 1JBVA 4BUBA 1Q1MA 5LXQB 2FH7A 3I36A 2I4GA 1GWZA 2J17A 2UUPA 2F71A 2XPCA 2CMAA 1ZC0A 3V0GA 1OHCA 1PYNA 2I6IA 2GP0A 2Q05A 4ERCA 3BLTA 3ZV2A 1GQYA 4I8NA 4CVMA 1LQFA 2I42A 5IBMA 2B4PA 1M3GA 3ZMQA 2H03A 5EHRA 2F6YA 2ZMMA 1SUGA 2NT7A 2HC1A 4QBWA 2A3KA 3MOZA 3V0IA 2P4DA 2B3OA 2PI7A 4RH5A 2JJDA 1R6HA 1G1FA 3QCCA 1OEVA 3AWGA 4S0GA 4OHLA 1WRMA 4H34A 4HRFA 3U96A 2VTEA 3LK7A 3QCNA 2E0TA 2J16A 4MBBA 3RGQA 2ZN7A 3D9CA 4RDDA 2AHSA 2Q47A 4QBEA 1W78A 3ZM2A 2QBQA 3F9AA 2NTAA 2JFHA 2SHPA 1YTSA 2HNQA 3QKPA 2CNEA 1G7GA 2QBSA 4IKCA 4NYHA 1AAXA 3I7ZA 4JMJA 5KABA 4JBCA 1YWFA 3F99A 1P15A 1PTTA 1T4JA 2C46A 3D42A 2CNIA 1EENA 2PA5A 1NWLA 1YN9A 2VEUA 4B04A 1I9SA 2WTZA 5BX1A 1QXKA 4Y2EA 2J16B 3EAXA 5KA4A 3RO1A 1U25A 2CM7A 1T48A 1FGSA 1WCHA 1T49A 3QCFA 2ESBA 2OZ5A 1Q6JA 2F6VA 4WTYA 2B49A 2F70A 1GFYA 3S3EA 2PSZA 5K24A 2CMCA 1E8CA 2BGEA 2UAGA 4BUCA 2GCBA 4QAPA 4RI5A 3O3LA 5K22A 2HB1A 3QCKA 2I6MA 2AM1A 4QUNA 3UAGA 1J4XA 2VTDA 1Q6MA 1C84A 3V0EA 4DGXA 2HVLA 1C88A 2AZRA 1OESA 3LJ8A 4OHHA 4R30A 3O4UA 5K9VA 3EZZA 1X24A 2QDCA 2GC6A 4PYHA 2DXPA 1BZCA 1PTVA 4NNDA 1C86A 5A5EA 1E0DA 1Q6PA 2B4UA 2I6JA 3MVNA 1G1HA 2F6ZA 3ZL8A 4YAAA 4D3QA 5K9WA 2I4EA 2JFFA 2CNGA 2I3UA 3AWFA 2I1YA 3AWEA 1OHEA 3QCJA 1P3DA 4KI9A 5K23A 4JMKA 2H04A 1RXDA 3O4SA 1WAXA 1ZZWA 4OHIA 3H2XA 4QUMA 3V0DA 2CM3A 1NO6A 1G4US 4GS0A 4BJOA 3QCIA 2OC3A 3ZM3A 3BRHA 2HNPA 5KADA 5KAAA 1YTWA 3QCZA 3V0HA 1XXPA 4GFVA 1OETA 2NT2A 4GE6A 1YGUA 2G6ZA 2X5OA 2I6OA 4UAGA 2Y67A 2NZ6A 3QCDA 2NLKA 1P31A 3O4TA 1U26A 2F6WA 1XXVA 4D3RA 1OHDA 3ZM1A 5GTJA 1ZCLA 1PA1A 3RZ2A 5KA0A 1A5YA 3MOWA 3S3FA 2CNHA 1W7KA 4QF5A 4R0TA 4KYRA 4C12A 4Z6BA 2Y96A 4R0SA 1ZCKA 1NWEA 5BZXA 3F81A 4HJQA 2B4OA 5BZZA 1YZ4A 4GRZA 4OHDA 2C7SA 2JFGA 3EB1A 3B7OA 1PXHA 4H1OA 3O5XA 2A8BA 2I75A 2QDMA 4D3PA 3MMJA 3V0FA 1J6UA 2QBRA 1LYVA 2NV5A 3S3HA 4J51A 3NMEA 3D1QA 5MMZB 4CVLA 2FJNA 2M3VA 1C83A 4DGPA 2I4HA 3QCBA 3CWEA 3QCEA 2VEXA 2I6PA 1GQQA 5IBSA 3GXGA 1V3AA 3S4OA 3ZM5A 1OEUA 5KACA 1XM2A 4CVKA 1I57A 3QCGA 3SMEA 4WU3A 3QCHA 4RHGA 1YPTA 3A5KA 4GE5A 1EEHA 3N0AA 4ZRTA 1PA9A 3D1HA 4NX8A 2QCTA 2XJAA 1MKPA 2PT0A 2CNFA 3CM3A 2H4GA 2P6XA 3QCLA 4HV4A 1D5RA 1C85A 4ICZA 4RH9A 2HY3A 2CJZA 3HN7A 3D44A 1G7FA 4YR8B 5KA9A 2B07A 1NZ7A 1FPZA 3V0JA 1Q6SA 2OUDA 1LARA 1UAGA 2F46A 1EEOA 2UUOA 4JNBA 2F6FA 3SR9A 3BLUA 4QAHA 2BIJA 2VORA 1OEOX 1YGRA 2BGDA 1JLNA 4TVVA 1XBOA 3ZM0A 4ZIYA 4ZN5A 2VEVA 1PTUA 5AWXA 1GG4A 2WJPA 3RGOA 1NL9A 2CM2A 3EU0A 1Q6TA 2MBCA 4OHEA 3ZMPA 4GWFA 2YDUA 3GXHA 4AZ1A 3S4EA 4GRYA 3N2AA 2Y66A 3S3KA 1JF7A 2FJMA 3F41A 1BZHA 5M43A 2VEYA 3QCMA 2QBPA 1G4WR 4RKKA 2Y2FA 3A5JA 5I6VA 1PTYA 5A5FA 2OOQA 1FQ1A 1NNYA 2CM8A 3F9BA 1YTNA 3D1OA 2GC5A 2PQ5A 2R0BA 1ECVA 1ONZA 3OLRA 3PYZA 2VEWA 1Q6NA 4Y14A 2HXPA 3ZM6A 1FPRA 3M4UA 3PS5A 5HDEA 4KYQA 2Y1OA 2Y68A 5BUGA 1C87A 4QDIA 5KA8A 5KA7A 1I9TA 4GE2A 4WOHA 3QKQA 1KAKA 1U24A 2CFVA 5K25A 2H02A 2GWOA 1VHRA 5KA2A 4RI4A 1RPMA 3I80A 2H4KA 2I3RA 2F00A 5KA1A 2WGPA 3BM8A 2QCJA 2H4VA 1PH0A 2IMGA 2CMBA 2F6TA 2B4SA 2HC2A 2PBNA 2HCMA 4BPCA 3EMUA 4GFUA 2BV5A 2BZLA 4C13A 1O5ZA 4NWGA 1ONYA 2RF6A 4HJPA 4ZI4A 5KA3A 1JBWA 1G1GA
chains in the Genus database with same CATH topology
2I5XA 5J8RA 1OEMX 2QEPA 1BZJA 2G59A 4WU2A 1XRIA 1L8KA 5EHPA 4NWFA 1L8GA 1QZ0A 4PVGA 1YFOA 3OMHA 2QDPA 1KAVA 2GJTA 1Q1MA 5LXQB 2FH7A 3I36A 2I4GA 1GWZA 2J17A 2F71A 2CMAA 1ZC0A 3V0GA 1OHCA 1PYNA 2I6IA 2GP0A 2Q05A 4ERCA 3BLTA 3ZV2A 4I8NA 1LQFA 2I42A 5IBMA 2B4PA 1M3GA 3ZMQA 2H03A 5EHRA 2F6YA 2ZMMA 1SUGA 2NT7A 2HC1A 4QBWA 2A3KA 3MOZA 3V0IA 2P4DA 2B3OA 2PI7A 4RH5A 2JJDA 1R6HA 1G1FA 3QCCA 1OEVA 3AWGA 4S0GA 4OHLA 1WRMA 4H34A 4HRFA 3U96A 3QCNA 2E0TA 2J16A 4MBBA 3RGQA 2ZN7A 3D9CA 4RDDA 2AHSA 2Q47A 4QBEA 3ZM2A 2QBQA 3F9AA 2NTAA 2SHPA 1YTSA 2HNQA 3QKPA 2CNEA 1G7GA 2QBSA 4IKCA 4NYHA 1AAXA 3I7ZA 4JMJA 5KABA 4JBCA 1YWFA 3F99A 1P15A 1PTTA 1T4JA 2C46A 3D42A 2CNIA 1EENA 2PA5A 1NWLA 1YN9A 2VEUA 4B04A 1I9SA 5BX1A 1QXKA 4Y2EA 2J16B 3EAXA 5KA4A 3RO1A 1U25A 2CM7A 1T48A 1WCHA 1T49A 3QCFA 2ESBA 2OZ5A 1Q6JA 2F6VA 4WTYA 2B49A 2F70A 1GFYA 3S3EA 2PSZA 5K24A 2CMCA 2BGEA 4QAPA 4RI5A 3O3LA 5K22A 2HB1A 3QCKA 2I6MA 4QUNA 1J4XA 1Q6MA 1C84A 3V0EA 4DGXA 2HVLA 1C88A 2AZRA 1OESA 3LJ8A 4OHHA 4R30A 3O4UA 5K9VA 3EZZA 1X24A 2QDCA 4PYHA 2DXPA 1BZCA 1PTVA 4NNDA 1C86A 1Q6PA 2B4UA 2I6JA 1G1HA 2F6ZA 4YAAA 4D3QA 5K9WA 2I4EA 2CNGA 2I3UA 3AWFA 2I1YA 3AWEA 1OHEA 3QCJA 4KI9A 5K23A 4JMKA 2H04A 1RXDA 3O4SA 1WAXA 1ZZWA 4OHIA 3H2XA 4QUMA 3V0DA 2CM3A 1NO6A 1G4US 4GS0A 4BJOA 3QCIA 2OC3A 3ZM3A 3BRHA 2HNPA 5KADA 5KAAA 1YTWA 3V0HA 1XXPA 4GFVA 1OETA 2NT2A 4GE6A 1YGUA 2G6ZA 2I6OA 2NZ6A 3QCDA 2NLKA 3O4TA 1U26A 2F6WA 1XXVA 4D3RA 1OHDA 3ZM1A 5GTJA 1ZCLA 1PA1A 3RZ2A 5KA0A 1A5YA 3MOWA 3S3FA 2CNHA 4R0TA 4KYRA 4Z6BA 2Y96A 4R0SA 1ZCKA 1NWEA 5BZXA 3F81A 4HJQA 2B4OA 5BZZA 1YZ4A 4GRZA 4OHDA 2C7SA 3EB1A 3B7OA 1PXHA 4H1OA 3O5XA 2A8BA 2I75A 2QDMA 4D3PA 3MMJA 3V0FA 2QBRA 1LYVA 2NV5A 3S3HA 4J51A 3NMEA 3D1QA 5MMZB 2FJNA 2M3VA 1C83A 4DGPA 2I4HA 3QCBA 3CWEA 3QCEA 2VEXA 2I6PA 5IBSA 3GXGA 1V3AA 3S4OA 1OEUA 5KACA 1XM2A 1I57A 3QCGA 3SMEA 4WU3A 3QCHA 4RHGA 1YPTA 3A5KA 4GE5A 3N0AA 4ZRTA 1PA9A 3D1HA 4NX8A 2QCTA 1MKPA 2PT0A 2CNFA 3CM3A 2H4GA 3QCLA 2P6XA 1D5RA 1C85A 4ICZA 4RH9A 2HY3A 2CJZA 3D44A 1G7FA 4YR8B 5KA9A 2B07A 1NZ7A 1FPZA 3V0JA 1Q6SA 2OUDA 1LARA 2F46A 1EEOA 4JNBA 2F6FA 3SR9A 3BLUA 4QAHA 2BIJA 1OEOX 1YGRA 2BGDA 1JLNA 4TVVA 1XBOA 3ZM0A 4ZN5A 2VEVA 1PTUA 5AWXA 3RGOA 1NL9A 2CM2A 3EU0A 1Q6TA 2MBCA 4OHEA 3ZMPA 4GWFA 2YDUA 3GXHA 4AZ1A 3S4EA 4GRYA 3S3KA 1JF7A 2FJMA 3F41A 1BZHA 5M43A 2VEYA 3QCMA 2QBPA 1G4WR 4RKKA 2Y2FA 3A5JA 5I6VA 1PTYA 2OOQA 1FQ1A 1NNYA 2CM8A 3F9BA 1YTNA 3D1OA 2PQ5A 2R0BA 1ECVA 1ONZA 3OLRA 2VEWA 1Q6NA 4Y14A 2HXPA 1FPRA 3M4UA 3PS5A 5HDEA 4KYQA 5BUGA 1C87A 5KA8A 5KA7A 1I9TA 4GE2A 4WOHA 3QKQA 1KAKA 1U24A 2CFVA 5K25A 2H02A 2GWOA 1VHRA 5KA2A 4RI4A 1RPMA 3I80A 2H4KA 2I3RA 5KA1A 2WGPA 3BM8A 2QCJA 2H4VA 1PH0A 2IMGA 2CMBA 2F6TA 2B4SA 2HC2A 2PBNA 2HCMA 4BPCA 3EMUA 4GFUA 2BV5A 2BZLA 4NWGA 1ONYA 2RF6A 4HJPA 4ZI4A 5KA3A 1G1GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2I5X A;  5J8R A;  1OEM X;  2QEP A;  1BZJ A;  2G59 A;  4WU2 A;  1XRI A;  1L8K A;  5EHP A;  4NWF A;  1L8G A;  1QZ0 A;  4PVG A;  1YFO A;  3OMH A;  2QDP A;  1KAV A;  2GJT A;  1Q1M A;  5LXQ B;  2FH7 A;  3I36 A;  2I4G A;  1GWZ A;  2J17 A;  2F71 A;  2CMA A;  1ZC0 A;  3V0G A;  1OHC A;  1PYN A;  2I6I A;  2GP0 A;  2Q05 A;  4ERC A;  3BLT A;  3ZV2 A;  4I8N A;  1LQF A;  2I42 A;  5IBM A;  2B4P A;  1M3G A;  3ZMQ A;  2H03 A;  5EHR A;  2F6Y A;  2ZMM A;  1SUG A;  2NT7 A;  2HC1 A;  4QBW A;  2A3K A;  3MOZ A;  3V0I A;  2P4D A;  2B3O A;  2PI7 A;  4RH5 A;  2JJD A;  1R6H A;  1G1F A;  3QCC A;  1OEV A;  3AWG A;  4S0G A;  4OHL A;  1WRM A;  4H34 A;  4HRF A;  3U96 A;  3QCN A;  2E0T A;  2J16 A;  4MBB A;  3RGQ A;  2ZN7 A;  3D9C A;  4RDD A;  2AHS A;  2Q47 A;  4QBE A;  3ZM2 A;  2QBQ A;  3F9A A;  2NTA A;  2SHP A;  1YTS A;  2HNQ A;  3QKP A;  2CNE A;  1G7G A;  2QBS A;  4IKC A;  4NYH A;  1AAX A;  3I7Z A;  4JMJ A;  5KAB A;  4JBC A;  1YWF A;  3F99 A;  1P15 A;  1PTT A;  1T4J A;  2C46 A;  3D42 A;  2CNI A;  1EEN A;  2PA5 A;  1NWL A;  1YN9 A;  2VEU A;  4B04 A;  1I9S A;  5BX1 A;  1QXK A;  4Y2E A;  2J16 B;  3EAX A;  5KA4 A;  3RO1 A;  1U25 A;  2CM7 A;  1T48 A;  1WCH A;  1T49 A;  3QCF A;  2ESB A;  2OZ5 A;  1Q6J A;  2F6V A;  4WTY A;  2B49 A;  2F70 A;  1GFY A;  3S3E A;  2PSZ A;  5K24 A;  2CMC A;  2BGE A;  4QAP A;  4RI5 A;  3O3L A;  5K22 A;  2HB1 A;  3QCK A;  2I6M A;  4QUN A;  1J4X A;  1Q6M A;  1C84 A;  3V0E A;  4DGX A;  2HVL A;  1C88 A;  2AZR A;  1OES A;  3LJ8 A;  4OHH A;  4R30 A;  3O4U A;  5K9V A;  3EZZ A;  1X24 A;  2QDC A;  4PYH A;  2DXP A;  1BZC A;  1PTV A;  4NND A;  1C86 A;  1Q6P A;  2B4U A;  2I6J A;  1G1H A;  2F6Z A;  4YAA A;  4D3Q A;  5K9W A;  2I4E A;  2CNG A;  2I3U A;  3AWF A;  2I1Y A;  3AWE A;  1OHE A;  3QCJ A;  4KI9 A;  5K23 A;  4JMK A;  2H04 A;  1RXD A;  3O4S A;  1WAX A;  1ZZW A;  4OHI A;  3H2X A;  4QUM A;  3V0D A;  2CM3 A;  1NO6 A;  1G4U S;  4GS0 A;  4BJO A;  3QCI A;  2OC3 A;  3ZM3 A;  3BRH A;  2HNP A;  5KAD A;  5KAA A;  1YTW A;  3V0H A;  1XXP A;  4GFV A;  1OET A;  2NT2 A;  4GE6 A;  1YGU A;  2G6Z A;  2I6O A;  2NZ6 A;  3QCD A;  2NLK A;  3O4T A;  1U26 A;  2F6W A;  1XXV A;  4D3R A;  1OHD A;  3ZM1 A;  5GTJ A;  1ZCL A;  1PA1 A;  3RZ2 A;  5KA0 A;  1A5Y A;  3MOW A;  3S3F A;  2CNH A;  4R0T A;  4KYR A;  4Z6B A;  2Y96 A;  4R0S A;  1ZCK A;  1NWE A;  5BZX A;  3F81 A;  4HJQ A;  2B4O A;  5BZZ A;  1YZ4 A;  4GRZ A;  4OHD A;  2C7S A;  3EB1 A;  3B7O A;  1PXH A;  4H1O A;  3O5X A;  2A8B A;  2I75 A;  2QDM A;  4D3P A;  3MMJ A;  3V0F A;  2QBR A;  1LYV A;  2NV5 A;  3S3H A;  4J51 A;  3NME A;  3D1Q A;  5MMZ B;  2FJN A;  2M3V A;  1C83 A;  4DGP A;  2I4H A;  3QCB A;  3CWE A;  3QCE A;  2VEX A;  2I6P A;  5IBS A;  3GXG A;  1V3A A;  3S4O A;  1OEU A;  5KAC A;  1XM2 A;  1I57 A;  3QCG A;  3SME A;  4WU3 A;  3QCH A;  4RHG A;  1YPT A;  3A5K A;  4GE5 A;  3N0A A;  4ZRT A;  1PA9 A;  3D1H A;  4NX8 A;  2QCT A;  1MKP A;  2PT0 A;  2CNF A;  3CM3 A;  2H4G A;  3QCL A;  2P6X A;  1D5R A;  1C85 A;  4ICZ A;  4RH9 A;  2HY3 A;  2CJZ A;  3D44 A;  1G7F A;  4YR8 B;  5KA9 A;  2B07 A;  1NZ7 A;  1FPZ A;  3V0J A;  1Q6S A;  2OUD A;  1LAR A;  2F46 A;  1EEO A;  4JNB A;  2F6F A;  3SR9 A;  3BLU A;  4QAH A;  2BIJ A;  1OEO X;  1YGR A;  2BGD A;  1JLN A;  4TVV A;  1XBO A;  3ZM0 A;  4ZN5 A;  2VEV A;  1PTU A;  5AWX A;  3RGO A;  1NL9 A;  2CM2 A;  3EU0 A;  1Q6T A;  2MBC A;  4OHE A;  3ZMP A;  4GWF A;  2YDU A;  3GXH A;  4AZ1 A;  3S4E A;  4GRY A;  3S3K A;  1JF7 A;  2FJM A;  3F41 A;  1BZH A;  5M43 A;  2VEY A;  3QCM A;  2QBP A;  1G4W R;  4RKK A;  2Y2F A;  3A5J A;  5I6V A;  1PTY A;  2OOQ A;  1FQ1 A;  1NNY A;  2CM8 A;  3F9B A;  1YTN A;  3D1O A;  2PQ5 A;  2R0B A;  1ECV A;  1ONZ A;  3OLR A;  2VEW A;  1Q6N A;  4Y14 A;  2HXP A;  1FPR A;  3M4U A;  3PS5 A;  5HDE A;  4KYQ A;  5BUG A;  1C87 A;  5KA8 A;  5KA7 A;  1I9T A;  4GE2 A;  4WOH A;  3QKQ A;  1KAK A;  1U24 A;  2CFV A;  5K25 A;  2H02 A;  2GWO A;  1VHR A;  5KA2 A;  4RI4 A;  1RPM A;  3I80 A;  2H4K A;  2I3R A;  5KA1 A;  2WGP A;  3BM8 A;  2QCJ A;  2H4V A;  1PH0 A;  2IMG A;  2CMB A;  2F6T A;  2B4S A;  2HC2 A;  2PBN A;  2HCM A;  4BPC A;  3EMU A;  4GFU A;  2BV5 A;  2BZL A;  4NWG A;  1ONY A;  2RF6 A;  4HJP A;  4ZI4 A;  5KA3 A;  1G1G A; 
#chains in the Genus database with same CATH topology
 2GCA A;  2I5X A;  5J8R A;  1OEM X;  2QEP A;  1BZJ A;  2G59 A;  4WU2 A;  1XRI A;  1L8K A;  5EHP A;  2VOS A;  4NWF A;  1L8G A;  1QZ0 A;  4PVG A;  1YFO A;  3OMH A;  2QDP A;  1KAV A;  2AM2 A;  3NRS A;  2GJT A;  1JBV A;  4BUB A;  1Q1M A;  5LXQ B;  2FH7 A;  3I36 A;  2I4G A;  1GWZ A;  2J17 A;  2UUP A;  2F71 A;  2XPC A;  2CMA A;  1ZC0 A;  3V0G A;  1OHC A;  1PYN A;  2I6I A;  2GP0 A;  2Q05 A;  4ERC A;  3BLT A;  3ZV2 A;  1GQY A;  4I8N A;  4CVM A;  1LQF A;  2I42 A;  5IBM A;  2B4P A;  1M3G A;  3ZMQ A;  2H03 A;  5EHR A;  2F6Y A;  2ZMM A;  1SUG A;  2NT7 A;  2HC1 A;  4QBW A;  2A3K A;  3MOZ A;  3V0I A;  2P4D A;  2B3O A;  2PI7 A;  4RH5 A;  2JJD A;  1R6H A;  1G1F A;  3QCC A;  1OEV A;  3AWG A;  4S0G A;  4OHL A;  1WRM A;  4H34 A;  4HRF A;  3U96 A;  2VTE A;  3LK7 A;  3QCN A;  2E0T A;  2J16 A;  4MBB A;  3RGQ A;  2ZN7 A;  3D9C A;  4RDD A;  2AHS A;  2Q47 A;  4QBE A;  1W78 A;  3ZM2 A;  2QBQ A;  3F9A A;  2NTA A;  2JFH A;  2SHP A;  1YTS A;  2HNQ A;  3QKP A;  2CNE A;  1G7G A;  2QBS A;  4IKC A;  4NYH A;  1AAX A;  3I7Z A;  4JMJ A;  5KAB A;  4JBC A;  1YWF A;  3F99 A;  1P15 A;  1PTT A;  1T4J A;  2C46 A;  3D42 A;  2CNI A;  1EEN A;  2PA5 A;  1NWL A;  1YN9 A;  2VEU A;  4B04 A;  1I9S A;  2WTZ A;  5BX1 A;  1QXK A;  4Y2E A;  2J16 B;  3EAX A;  5KA4 A;  3RO1 A;  1U25 A;  2CM7 A;  1T48 A;  1FGS A;  1WCH A;  1T49 A;  3QCF A;  2ESB A;  2OZ5 A;  1Q6J A;  2F6V A;  4WTY A;  2B49 A;  2F70 A;  1GFY A;  3S3E A;  2PSZ A;  5K24 A;  2CMC A;  1E8C A;  2BGE A;  2UAG A;  4BUC A;  2GCB A;  4QAP A;  4RI5 A;  3O3L A;  5K22 A;  2HB1 A;  3QCK A;  2I6M A;  2AM1 A;  4QUN A;  3UAG A;  1J4X A;  2VTD A;  1Q6M A;  1C84 A;  3V0E A;  4DGX A;  2HVL A;  1C88 A;  2AZR A;  1OES A;  3LJ8 A;  4OHH A;  4R30 A;  3O4U A;  5K9V A;  3EZZ A;  1X24 A;  2QDC A;  2GC6 A;  4PYH A;  2DXP A;  1BZC A;  1PTV A;  4NND A;  1C86 A;  5A5E A;  1E0D A;  1Q6P A;  2B4U A;  2I6J A;  3MVN A;  1G1H A;  2F6Z A;  3ZL8 A;  4YAA A;  4D3Q A;  5K9W A;  2I4E A;  2JFF A;  2CNG A;  2I3U A;  3AWF A;  2I1Y A;  3AWE A;  1OHE A;  3QCJ A;  1P3D A;  4KI9 A;  5K23 A;  4JMK A;  2H04 A;  1RXD A;  3O4S A;  1WAX A;  1ZZW A;  4OHI A;  3H2X A;  4QUM A;  3V0D A;  2CM3 A;  1NO6 A;  1G4U S;  4GS0 A;  4BJO A;  3QCI A;  2OC3 A;  3ZM3 A;  3BRH A;  2HNP A;  5KAD A;  5KAA A;  1YTW A;  3QCZ A;  3V0H A;  1XXP A;  4GFV A;  1OET A;  2NT2 A;  4GE6 A;  1YGU A;  2G6Z A;  2X5O A;  2I6O A;  4UAG A;  2Y67 A;  2NZ6 A;  3QCD A;  2NLK A;  1P31 A;  3O4T A;  1U26 A;  2F6W A;  1XXV A;  4D3R A;  1OHD A;  3ZM1 A;  5GTJ A;  1ZCL A;  1PA1 A;  3RZ2 A;  5KA0 A;  1A5Y A;  3MOW A;  3S3F A;  2CNH A;  1W7K A;  4QF5 A;  4R0T A;  4KYR A;  4C12 A;  4Z6B A;  2Y96 A;  4R0S A;  1ZCK A;  1NWE A;  5BZX A;  3F81 A;  4HJQ A;  2B4O A;  5BZZ A;  1YZ4 A;  4GRZ A;  4OHD A;  2C7S A;  2JFG A;  3EB1 A;  3B7O A;  1PXH A;  4H1O A;  3O5X A;  2A8B A;  2I75 A;  2QDM A;  4D3P A;  3MMJ A;  3V0F A;  1J6U A;  2QBR A;  1LYV A;  2NV5 A;  3S3H A;  4J51 A;  3NME A;  3D1Q A;  5MMZ B;  4CVL A;  2FJN A;  2M3V A;  1C83 A;  4DGP A;  2I4H A;  3QCB A;  3CWE A;  3QCE A;  2VEX A;  2I6P A;  1GQQ A;  5IBS A;  3GXG A;  1V3A A;  3S4O A;  3ZM5 A;  1OEU A;  5KAC A;  1XM2 A;  4CVK A;  1I57 A;  3QCG A;  3SME A;  4WU3 A;  3QCH A;  4RHG A;  1YPT A;  3A5K A;  4GE5 A;  1EEH A;  3N0A A;  4ZRT A;  1PA9 A;  3D1H A;  4NX8 A;  2QCT A;  2XJA A;  1MKP A;  2PT0 A;  2CNF A;  3CM3 A;  2H4G A;  2P6X A;  3QCL A;  4HV4 A;  1D5R A;  1C85 A;  4ICZ A;  4RH9 A;  2HY3 A;  2CJZ A;  3HN7 A;  3D44 A;  1G7F A;  4YR8 B;  5KA9 A;  2B07 A;  1NZ7 A;  1FPZ A;  3V0J A;  1Q6S A;  2OUD A;  1LAR A;  1UAG A;  2F46 A;  1EEO A;  2UUO A;  4JNB A;  2F6F A;  3SR9 A;  3BLU A;  4QAH A;  2BIJ A;  2VOR A;  1OEO X;  1YGR A;  2BGD A;  1JLN A;  4TVV A;  1XBO A;  3ZM0 A;  4ZIY A;  4ZN5 A;  2VEV A;  1PTU A;  5AWX A;  1GG4 A;  2WJP A;  3RGO A;  1NL9 A;  2CM2 A;  3EU0 A;  1Q6T A;  2MBC A;  4OHE A;  3ZMP A;  4GWF A;  2YDU A;  3GXH A;  4AZ1 A;  3S4E A;  4GRY A;  3N2A A;  2Y66 A;  3S3K A;  1JF7 A;  2FJM A;  3F41 A;  1BZH A;  5M43 A;  2VEY A;  3QCM A;  2QBP A;  1G4W R;  4RKK A;  2Y2F A;  3A5J A;  5I6V A;  1PTY A;  5A5F A;  2OOQ A;  1FQ1 A;  1NNY A;  2CM8 A;  3F9B A;  1YTN A;  3D1O A;  2GC5 A;  2PQ5 A;  2R0B A;  1ECV A;  1ONZ A;  3OLR A;  3PYZ A;  2VEW A;  1Q6N A;  4Y14 A;  2HXP A;  3ZM6 A;  1FPR A;  3M4U A;  3PS5 A;  5HDE A;  4KYQ A;  2Y1O A;  2Y68 A;  5BUG A;  1C87 A;  4QDI A;  5KA8 A;  5KA7 A;  1I9T A;  4GE2 A;  4WOH A;  3QKQ A;  1KAK A;  1U24 A;  2CFV A;  5K25 A;  2H02 A;  2GWO A;  1VHR A;  5KA2 A;  4RI4 A;  1RPM A;  3I80 A;  2H4K A;  2I3R A;  2F00 A;  5KA1 A;  2WGP A;  3BM8 A;  2QCJ A;  2H4V A;  1PH0 A;  2IMG A;  2CMB A;  2F6T A;  2B4S A;  2HC2 A;  2PBN A;  2HCM A;  4BPC A;  3EMU A;  4GFU A;  2BV5 A;  2BZL A;  4C13 A;  1O5Z A;  4NWG A;  1ONY A;  2RF6 A;  4HJP A;  4ZI4 A;  5KA3 A;  1JBW A;  1G1G A; 
#chains in the Genus database with same CATH homology
 2I5X A;  5J8R A;  1OEM X;  2QEP A;  1BZJ A;  2G59 A;  4WU2 A;  1XRI A;  1L8K A;  5EHP A;  4NWF A;  1L8G A;  1QZ0 A;  4PVG A;  1YFO A;  3OMH A;  2QDP A;  1KAV A;  2GJT A;  1Q1M A;  5LXQ B;  2FH7 A;  3I36 A;  2I4G A;  1GWZ A;  2J17 A;  2F71 A;  2CMA A;  1ZC0 A;  3V0G A;  1OHC A;  1PYN A;  2I6I A;  2GP0 A;  2Q05 A;  4ERC A;  3BLT A;  3ZV2 A;  4I8N A;  1LQF A;  2I42 A;  5IBM A;  2B4P A;  1M3G A;  3ZMQ A;  2H03 A;  5EHR A;  2F6Y A;  2ZMM A;  1SUG A;  2NT7 A;  2HC1 A;  4QBW A;  2A3K A;  3MOZ A;  3V0I A;  2P4D A;  2B3O A;  2PI7 A;  4RH5 A;  2JJD A;  1R6H A;  1G1F A;  3QCC A;  1OEV A;  3AWG A;  4S0G A;  4OHL A;  1WRM A;  4H34 A;  4HRF A;  3U96 A;  3QCN A;  2E0T A;  2J16 A;  4MBB A;  3RGQ A;  2ZN7 A;  3D9C A;  4RDD A;  2AHS A;  2Q47 A;  4QBE A;  3ZM2 A;  2QBQ A;  3F9A A;  2NTA A;  2SHP A;  1YTS A;  2HNQ A;  3QKP A;  2CNE A;  1G7G A;  2QBS A;  4IKC A;  4NYH A;  1AAX A;  3I7Z A;  4JMJ A;  5KAB A;  4JBC A;  1YWF A;  3F99 A;  1P15 A;  1PTT A;  1T4J A;  2C46 A;  3D42 A;  2CNI A;  1EEN A;  2PA5 A;  1NWL A;  1YN9 A;  2VEU A;  4B04 A;  1I9S A;  5BX1 A;  1QXK A;  4Y2E A;  2J16 B;  3EAX A;  5KA4 A;  3RO1 A;  1U25 A;  2CM7 A;  1T48 A;  1WCH A;  1T49 A;  3QCF A;  2ESB A;  2OZ5 A;  1Q6J A;  2F6V A;  4WTY A;  2B49 A;  2F70 A;  1GFY A;  3S3E A;  2PSZ A;  5K24 A;  2CMC A;  2BGE A;  4QAP A;  4RI5 A;  3O3L A;  5K22 A;  2HB1 A;  3QCK A;  2I6M A;  4QUN A;  1J4X A;  1Q6M A;  1C84 A;  3V0E A;  4DGX A;  2HVL A;  1C88 A;  2AZR A;  1OES A;  3LJ8 A;  4OHH A;  4R30 A;  3O4U A;  5K9V A;  3EZZ A;  1X24 A;  2QDC A;  4PYH A;  2DXP A;  1BZC A;  1PTV A;  4NND A;  1C86 A;  1Q6P A;  2B4U A;  2I6J A;  1G1H A;  2F6Z A;  4YAA A;  4D3Q A;  5K9W A;  2I4E A;  2CNG A;  2I3U A;  3AWF A;  2I1Y A;  3AWE A;  1OHE A;  3QCJ A;  4KI9 A;  5K23 A;  4JMK A;  2H04 A;  1RXD A;  3O4S A;  1WAX A;  1ZZW A;  4OHI A;  3H2X A;  4QUM A;  3V0D A;  2CM3 A;  1NO6 A;  1G4U S;  4GS0 A;  4BJO A;  3QCI A;  2OC3 A;  3ZM3 A;  3BRH A;  2HNP A;  5KAD A;  5KAA A;  1YTW A;  3V0H A;  1XXP A;  4GFV A;  1OET A;  2NT2 A;  4GE6 A;  1YGU A;  2G6Z A;  2I6O A;  2NZ6 A;  3QCD A;  2NLK A;  3O4T A;  1U26 A;  2F6W A;  1XXV A;  4D3R A;  1OHD A;  3ZM1 A;  5GTJ A;  1ZCL A;  1PA1 A;  3RZ2 A;  5KA0 A;  1A5Y A;  3MOW A;  3S3F A;  2CNH A;  4R0T A;  4KYR A;  4Z6B A;  2Y96 A;  4R0S A;  1ZCK A;  1NWE A;  5BZX A;  3F81 A;  4HJQ A;  2B4O A;  5BZZ A;  1YZ4 A;  4GRZ A;  4OHD A;  2C7S A;  3EB1 A;  3B7O A;  1PXH A;  4H1O A;  3O5X A;  2A8B A;  2I75 A;  2QDM A;  4D3P A;  3MMJ A;  3V0F A;  2QBR A;  1LYV A;  2NV5 A;  3S3H A;  4J51 A;  3NME A;  3D1Q A;  5MMZ B;  2FJN A;  2M3V A;  1C83 A;  4DGP A;  2I4H A;  3QCB A;  3CWE A;  3QCE A;  2VEX A;  2I6P A;  5IBS A;  3GXG A;  1V3A A;  3S4O A;  1OEU A;  5KAC A;  1XM2 A;  1I57 A;  3QCG A;  3SME A;  4WU3 A;  3QCH A;  4RHG A;  1YPT A;  3A5K A;  4GE5 A;  3N0A A;  4ZRT A;  1PA9 A;  3D1H A;  4NX8 A;  2QCT A;  1MKP A;  2PT0 A;  2CNF A;  3CM3 A;  2H4G A;  3QCL A;  2P6X A;  1D5R A;  1C85 A;  4ICZ A;  4RH9 A;  2HY3 A;  2CJZ A;  3D44 A;  1G7F A;  4YR8 B;  5KA9 A;  2B07 A;  1NZ7 A;  1FPZ A;  3V0J A;  1Q6S A;  2OUD A;  1LAR A;  2F46 A;  1EEO A;  4JNB A;  2F6F A;  3SR9 A;  3BLU A;  4QAH A;  2BIJ A;  1OEO X;  1YGR A;  2BGD A;  1JLN A;  4TVV A;  1XBO A;  3ZM0 A;  4ZN5 A;  2VEV A;  1PTU A;  5AWX A;  3RGO A;  1NL9 A;  2CM2 A;  3EU0 A;  1Q6T A;  2MBC A;  4OHE A;  3ZMP A;  4GWF A;  2YDU A;  3GXH A;  4AZ1 A;  3S4E A;  4GRY A;  3S3K A;  1JF7 A;  2FJM A;  3F41 A;  1BZH A;  5M43 A;  2VEY A;  3QCM A;  2QBP A;  1G4W R;  4RKK A;  2Y2F A;  3A5J A;  5I6V A;  1PTY A;  2OOQ A;  1FQ1 A;  1NNY A;  2CM8 A;  3F9B A;  1YTN A;  3D1O A;  2PQ5 A;  2R0B A;  1ECV A;  1ONZ A;  3OLR A;  2VEW A;  1Q6N A;  4Y14 A;  2HXP A;  1FPR A;  3M4U A;  3PS5 A;  5HDE A;  4KYQ A;  5BUG A;  1C87 A;  5KA8 A;  5KA7 A;  1I9T A;  4GE2 A;  4WOH A;  3QKQ A;  1KAK A;  1U24 A;  2CFV A;  5K25 A;  2H02 A;  2GWO A;  1VHR A;  5KA2 A;  4RI4 A;  1RPM A;  3I80 A;  2H4K A;  2I3R A;  5KA1 A;  2WGP A;  3BM8 A;  2QCJ A;  2H4V A;  1PH0 A;  2IMG A;  2CMB A;  2F6T A;  2B4S A;  2HC2 A;  2PBN A;  2HCM A;  4BPC A;  3EMU A;  4GFU A;  2BV5 A;  2BZL A;  4NWG A;  1ONY A;  2RF6 A;  4HJP A;  4ZI4 A;  5KA3 A;  1G1G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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