5KAAA

Protein tyrosine phosphatase 1b delta helix 7, p185g mutant, open state
Total Genus 93
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
93
sequence length
281
structure length
281
Chain Sequence
MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVGESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
total genus 93
structure length 281
sequence length 281
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2016-06-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 5kaaA00
3OMHA 2F46A 2PSZA 4H34A 2YDUA 5GTJA 3BLUA 1RPMA 2PBNA 5KACA 4NYHA 3CWEA 3ZMPA 2ZMMA 3GXHA 4YAAA 1U25A 2CMAA 1WRMA 1C86A 1YTSA 2F6YA 3O4TA 1PYNA 3V0EA 4BPCA 2Q05A 1G1GA 3MOZA 3O4UA 1PA9A 2J17A 1GWZA 2QBRA 4QUMA 2NTAA 4RI4A 1G1FA 3PS5A 3V0DA 4R0SA 4RDDA 4WOHA 5BZZA 1PTTA 3I7ZA 4NNDA 2QBPA 3O5XA 3QCEA 2ZN7A 2B3OA 4S0GA 3QCGA 1Q6PA 4OHLA 1T48A 2CMCA 4JNBA 1OEVA 1Q6SA 3D1QA 2CM8A 3QCNA 2I5XA 1XRIA 4HJQA 3V0HA 1VHRA 2M3VA 2H02A 3V0GA 3ZM1A 2CM2A 2F6TA 4GRZA 1WAXA 5K9VA 3F41A 1YPTA 1I57A 1YTNA 3QCKA 2NZ6A 4GE5A 2CM3A 4MBBA 5M43A 1XXPA 2I4GA 2OOQA 2QCTA 2CMBA 1C83A 2GWOA 1OESA 3QCBA 5KADA 1PXHA 1V3AA 2HNPA 2P4DA 4R0TA 1C84A 3AWFA 2VEXA 2FJNA 2VEUA 1EEOA 2AHSA 2RF6A 1C85A 4WU3A 2H4GA 4GS0A 2QDPA 1I9SA 3GXGA 2I6IA 2I6OA 4QBWA 5I6VA 2CNHA 2CNIA 3V0JA 1SUGA 1BZHA 4TVVA 1C88A 1ONZA 1X24A 3SR9A 2H04A 2I1YA 2CNFA 2H4VA 1A5YA 1FQ1A 4KI9A 5KA7A 3F81A 5KA3A 4GFUA 4ICZA 1ECVA 3F9AA 5AWXA 3S3EA 1XBOA 1KAKA 4DGXA 2HVLA 2J16A 1YZ4A 2CM7A 2F6VA 4GE2A 3S3KA 2GP0A 5IBSA 1U26A 2HNQA 1JF7A 2CNEA 4WTYA 3I80A 4HRFA 3QCMA 3I36A 4OHIA 4DGPA 5KA0A 3H2XA 2VEYA 4ERCA 3D1OA 4NWFA 4GRYA 5K25A 3N0AA 3EMUA 2H4KA 3EZZA 2HY3A 2NT2A 3O4SA 3LJ8A 3OLRA 4RH9A 1L8GA 1R6HA 1ZCKA 4OHDA 1PA1A 3MOWA 1G4WR 2MBCA 3D42A 4KYQA 1WCHA 4JMKA 1OHDA 5KA4A 2PT0A 2Y96A 1G4US 2R0BA 1LARA 2Q47A 4ZN5A 1Q1MA 5EHPA 2C46A 3D44A 4GFVA 1FPZA 1LQFA 2OUDA 1T4JA 2I6PA 3A5KA 2I6JA 4JMJA 2H03A 3AWGA 2QBSA 4GE6A 2DXPA 2B07A 4YR8B 5K23A 4BJOA 1G1HA 4RH5A 2F71A 2QDCA 3QCHA 1NWLA 2JJDA 1YN9A 2ESBA 4IKCA 5BZXA 1MKPA 2P6XA 3QCCA 3ZM0A 1JLNA 5LXQB 2A3KA 2Y2FA 2BZLA 3SMEA 2FJMA 2NT7A 1OEMX 3QCLA 2FH7A 3RZ2A 5IBMA 1OEOX 3U96A 2I6MA 2F6ZA 3QCJA 2CJZA 4ZI4A 4OHEA 5KA2A 5MMZB 1U24A 4WU2A 4QBEA 4Z6BA 1J4XA 2HCMA 4HJPA 1LYVA 2B4UA 1NNYA 2C7SA 3S3FA 1M3GA 1NZ7A 3O3LA 1XXVA 5K24A 2QBQA 1ZZWA 3F9BA 1NL9A 1Q6JA 1QZ0A 3A5JA 1YFOA 2B4OA 1P15A 3ZMQA 4B04A 4D3PA 3ZM3A 3M4UA 5HDEA 2G59A 2CNGA 3ZV2A 3D9CA 2HB1A 2PQ5A 2PA5A 2IMGA 2B49A 2B4PA 3S3HA 1OHEA 1L8KA 2F6WA 1ONYA 1AAXA 3QKQA 1YWFA 3BRHA 2BIJA 1Q6TA 3RO1A 1YGUA 5J8RA 2GJTA 4D3QA 4GWFA 1RXDA 3BM8A 4Y2EA 1OHCA 1BZCA 1Q6NA 1QXKA 2BV5A 4I8NA 2OZ5A 1ZC0A 4QAPA 4J51A 1XM2A 5BX1A 2PI7A 3BLTA 4NX8A 4RI5A 2SHPA 3QCDA 1NO6A 1PTUA 1OEUA 4QAHA 2QDMA 3RGQA 2F6FA 4RHGA 5KA1A 2A8BA 2I3RA 3AWEA 1C87A 2QCJA 3EU0A 2NV5A 3S4OA 1PTVA 5EHRA 2F70A 2E0TA 4KYRA 4OHHA 5K22A 2HC2A 3F99A 4RKKA 4D3RA 2HC1A 3V0IA 1YTWA 2I42A 2AZRA 2G6ZA 1BZJA 2WGPA 2J16B 3D1HA 1PH0A 3MMJA 5BUGA 2B4SA 4QUNA 3CM3A 4R30A 3EAXA 2I75A 5KABA 1T49A 1PTYA 2VEWA 2I4HA 1GFYA 1OETA 1NWEA 1YGRA 4NWGA 3S4EA 1G7FA 1FPRA 1G7GA 4ZRTA 3QKPA 2QEPA 4AZ1A 2BGDA 5K9WA 2I3UA 2I4EA 2BGEA 3EB1A 1D5RA 3B7OA 2OC3A 3QCFA 3RGOA 4PYHA 3QCIA 2VEVA 4PVGA 4H1OA 2HXPA 4JBCA 3NMEA 1Q6MA 4Y14A 2NLKA 1KAVA 1ZCLA 5KA9A 1EENA 1I9TA 3V0FA 3ZM2A 5KAAA 5KA8A 2CFVA
chains in the Genus database with same CATH superfamily
3OMHA 2F46A 2PSZA 4H34A 2YDUA 5GTJA 3BLUA 1RPMA 2PBNA 5KACA 4NYHA 3CWEA 4C13A 3ZMPA 3UAGA 2ZMMA 3GXHA 4YAAA 1U25A 2CMAA 1WRMA 1C86A 1YTSA 2F6YA 3O4TA 1PYNA 3V0EA 4BPCA 2Q05A 1G1GA 3MOZA 3O4UA 1PA9A 2J17A 1GWZA 2QBRA 4QUMA 2NTAA 2JFFA 4RI4A 1G1FA 3PS5A 3V0DA 4R0SA 4RDDA 4WOHA 5BZZA 1PTTA 2Y1OA 3I7ZA 4NNDA 2QBPA 3O5XA 3QCEA 2ZN7A 2XPCA 2UAGA 2B3OA 4S0GA 3QCGA 1Q6PA 1P3DA 1T48A 4OHLA 2CMCA 3NRSA 4JNBA 1OEVA 1Q6SA 2F00A 3D1QA 2CM8A 3QCNA 2I5XA 1XRIA 4HJQA 3V0HA 1VHRA 2M3VA 2H02A 3V0GA 3ZM1A 2CM2A 2F6TA 4GRZA 1WAXA 5K9VA 3F41A 1YPTA 1I57A 1YTNA 2NZ6A 3QCKA 4GE5A 2CM3A 4MBBA 5M43A 1XXPA 2I4GA 2OOQA 2QCTA 2CMBA 1C83A 2GWOA 1GQQA 1OESA 3QCBA 5KADA 1PXHA 1V3AA 2HNPA 2P4DA 4R0TA 1C84A 3AWFA 4QDIA 2VEXA 2FJNA 2VEUA 1EEOA 2AHSA 2RF6A 1C85A 4WU3A 2H4GA 4GS0A 2JFGA 2QDPA 1I9SA 3GXGA 4CVKA 2I6IA 2I6OA 4QBWA 5I6VA 2CNHA 2CNIA 3V0JA 2AM1A 1SUGA 1BZHA 1EEHA 5A5EA 4TVVA 2WTZA 1C88A 1ONZA 1X24A 3SR9A 2H04A 2I1YA 2CNFA 2H4VA 1A5YA 1FQ1A 4KI9A 5KA7A 3F81A 5KA3A 4GFUA 4ICZA 1UAGA 1ECVA 3F9AA 5AWXA 3S3EA 1XBOA 1KAKA 4DGXA 2HVLA 2J16A 1YZ4A 2CM7A 2JFHA 2F6VA 4GE2A 3S3KA 2GP0A 5IBSA 1U26A 2HNQA 1JF7A 2CNEA 4WTYA 3I80A 4HRFA 3QCMA 3I36A 4OHIA 4DGPA 5KA0A 3H2XA 2VEYA 2VOSA 4ERCA 3D1OA 3ZM5A 2VTDA 4NWFA 4GRYA 5K25A 3N0AA 3EMUA 2H4KA 3EZZA 2HY3A 2NT2A 3O4SA 4C12A 3LJ8A 3OLRA 4RH9A 1L8GA 1R6HA 1ZCKA 4OHDA 1PA1A 3QCZA 3MOWA 1G4WR 2MBCA 3D42A 4KYQA 1WCHA 4JMKA 1OHDA 2UUPA 5KA4A 2PT0A 1GG4A 2Y96A 1G4US 3MVNA 4BUCA 2XJAA 2R0BA 1LARA 1FGSA 2Q47A 4ZN5A 1Q1MA 5EHPA 2WJPA 2UUOA 2C46A 3D44A 4GFVA 1FPZA 1LQFA 2OUDA 1T4JA 1GQYA 2I6PA 3A5KA 2I6JA 1E8CA 4JMJA 2H03A 3AWGA 2QBSA 4GE6A 2DXPA 2B07A 2Y67A 4CVMA 4YR8B 5K23A 4BJOA 1G1HA 4RH5A 2F71A 2QDCA 3QCHA 1NWLA 2JJDA 1YN9A 2ESBA 4IKCA 5BZXA 4ZIYA 1E0DA 1MKPA 2P6XA 3QCCA 1J6UA 3ZM0A 1JLNA 5LXQB 2GC5A 2A3KA 2Y2FA 2BZLA 3SMEA 2FJMA 2NT7A 1OEMX 3QCLA 2FH7A 3RZ2A 5IBMA 1OEOX 1JBVA 2GCBA 3U96A 2Y68A 2I6MA 2F6ZA 3QCJA 2CJZA 4ZI4A 4OHEA 5KA2A 5MMZB 1U24A 4WU2A 3ZM6A 4QBEA 1O5ZA 4Z6BA 1J4XA 2HCMA 4HJPA 1LYVA 2B4UA 2VORA 1NNYA 2C7SA 3S3FA 1M3GA 1NZ7A 3O3LA 1XXVA 5K24A 2QBQA 1ZZWA 3F9BA 1NL9A 1Q6JA 1QZ0A 3A5JA 1YFOA 2B4OA 1P15A 3ZMQA 4B04A 4D3PA 3ZM3A 3M4UA 5HDEA 2G59A 2CNGA 3ZV2A 3D9CA 2HB1A 2PQ5A 2PA5A 2IMGA 2B49A 2B4PA 3S3HA 1OHEA 1L8KA 2F6WA 4HV4A 1ONYA 1AAXA 3QKQA 1YWFA 3BRHA 2BIJA 1Q6TA 3RO1A 1YGUA 5J8RA 2GJTA 4D3QA 4GWFA 1RXDA 2GC6A 3BM8A 3N2AA 4Y2EA 1OHCA 1BZCA 1Q6NA 2AM2A 2Y66A 1QXKA 2BV5A 4I8NA 2OZ5A 1ZC0A 4QAPA 4CVLA 1JBWA 4J51A 1XM2A 5BX1A 2PI7A 3BLTA 4NX8A 4RI5A 2SHPA 3QCDA 3ZL8A 2VTEA 1NO6A 2GCAA 1PTUA 1OEUA 4QAHA 2QDMA 3RGQA 2F6FA 4RHGA 5KA1A 2A8BA 2I3RA 3AWEA 1C87A 2QCJA 3EU0A 2NV5A 3S4OA 1PTVA 5EHRA 2F70A 2E0TA 3HN7A 5A5FA 4KYRA 4OHHA 5K22A 2HC2A 3F99A 4RKKA 4D3RA 2HC1A 3V0IA 1YTWA 2I42A 2AZRA 2G6ZA 1BZJA 4QF5A 2WGPA 2J16B 3D1HA 1PH0A 3MMJA 5BUGA 2B4SA 4QUNA 3CM3A 3PYZA 4R30A 4BUBA 3EAXA 4UAGA 2I75A 5KABA 1T49A 1PTYA 2VEWA 2I4HA 1GFYA 1OETA 1W78A 1NWEA 1YGRA 4NWGA 3S4EA 1G7FA 1FPRA 1G7GA 4ZRTA 3QKPA 2QEPA 4AZ1A 2BGDA 5K9WA 2I3UA 2I4EA 2BGEA 3EB1A 1D5RA 3B7OA 2OC3A 3QCFA 3RGOA 1P31A 4PYHA 3QCIA 2VEVA 4PVGA 3LK7A 4H1OA 2HXPA 4JBCA 3NMEA 1Q6MA 4Y14A 2NLKA 1KAVA 2X5OA 1ZCLA 5KA9A 1EENA 1I9TA 3V0FA 1W7KA 3ZM2A 5KA8A 5KAAA 2CFVA
chains in the Genus database with same CATH topology
3OMHA 2F46A 2PSZA 4H34A 2YDUA 5GTJA 3BLUA 1RPMA 2PBNA 5KACA 4NYHA 3CWEA 3ZMPA 2ZMMA 3GXHA 4YAAA 1U25A 2CMAA 1WRMA 1C86A 1YTSA 2F6YA 3O4TA 1PYNA 3V0EA 4BPCA 2Q05A 1G1GA 3MOZA 3O4UA 1PA9A 2J17A 1GWZA 2QBRA 4QUMA 2NTAA 4RI4A 1G1FA 3PS5A 3V0DA 4R0SA 4RDDA 4WOHA 5BZZA 1PTTA 3I7ZA 4NNDA 2QBPA 3O5XA 3QCEA 2ZN7A 2B3OA 4S0GA 3QCGA 1Q6PA 4OHLA 1T48A 2CMCA 4JNBA 1OEVA 1Q6SA 3D1QA 2CM8A 3QCNA 2I5XA 1XRIA 4HJQA 3V0HA 1VHRA 2M3VA 2H02A 3V0GA 3ZM1A 2CM2A 2F6TA 4GRZA 1WAXA 5K9VA 3F41A 1YPTA 1I57A 1YTNA 3QCKA 2NZ6A 4GE5A 2CM3A 4MBBA 5M43A 1XXPA 2I4GA 2OOQA 2QCTA 2CMBA 1C83A 2GWOA 1OESA 3QCBA 5KADA 1PXHA 1V3AA 2HNPA 2P4DA 4R0TA 1C84A 3AWFA 2VEXA 2FJNA 2VEUA 1EEOA 2AHSA 2RF6A 1C85A 4WU3A 2H4GA 4GS0A 2QDPA 1I9SA 3GXGA 2I6IA 2I6OA 4QBWA 5I6VA 2CNHA 2CNIA 3V0JA 1SUGA 1BZHA 4TVVA 1C88A 1ONZA 1X24A 3SR9A 2H04A 2I1YA 2CNFA 2H4VA 1A5YA 1FQ1A 4KI9A 5KA7A 3F81A 5KA3A 4GFUA 4ICZA 1ECVA 3F9AA 5AWXA 3S3EA 1XBOA 1KAKA 4DGXA 2HVLA 2J16A 1YZ4A 2CM7A 2F6VA 4GE2A 3S3KA 2GP0A 5IBSA 1U26A 2HNQA 1JF7A 2CNEA 4WTYA 3I80A 4HRFA 3QCMA 3I36A 4OHIA 4DGPA 5KA0A 3H2XA 2VEYA 4ERCA 3D1OA 4NWFA 4GRYA 5K25A 3N0AA 3EMUA 2H4KA 3EZZA 2HY3A 2NT2A 3O4SA 3LJ8A 3OLRA 4RH9A 1L8GA 1R6HA 1ZCKA 4OHDA 1PA1A 3MOWA 1G4WR 2MBCA 3D42A 4KYQA 1WCHA 4JMKA 1OHDA 5KA4A 2PT0A 2Y96A 1G4US 2R0BA 1LARA 2Q47A 4ZN5A 1Q1MA 5EHPA 2C46A 3D44A 4GFVA 1FPZA 1LQFA 2OUDA 1T4JA 2I6PA 3A5KA 2I6JA 4JMJA 2H03A 3AWGA 2QBSA 4GE6A 2DXPA 2B07A 4YR8B 5K23A 4BJOA 1G1HA 4RH5A 2F71A 2QDCA 3QCHA 1NWLA 2JJDA 1YN9A 2ESBA 4IKCA 5BZXA 1MKPA 2P6XA 3QCCA 3ZM0A 1JLNA 5LXQB 2A3KA 2Y2FA 2BZLA 3SMEA 2FJMA 2NT7A 1OEMX 3QCLA 2FH7A 3RZ2A 5IBMA 1OEOX 3U96A 2I6MA 2F6ZA 3QCJA 2CJZA 4ZI4A 4OHEA 5KA2A 5MMZB 1U24A 4WU2A 4QBEA 4Z6BA 1J4XA 2HCMA 4HJPA 1LYVA 2B4UA 1NNYA 2C7SA 3S3FA 1M3GA 1NZ7A 3O3LA 1XXVA 5K24A 2QBQA 1ZZWA 3F9BA 1NL9A 1Q6JA 1QZ0A 3A5JA 1YFOA 2B4OA 1P15A 3ZMQA 4B04A 4D3PA 3ZM3A 3M4UA 5HDEA 2G59A 2CNGA 3ZV2A 3D9CA 2HB1A 2PQ5A 2PA5A 2IMGA 2B49A 2B4PA 3S3HA 1OHEA 1L8KA 2F6WA 1ONYA 1AAXA 3QKQA 1YWFA 3BRHA 2BIJA 1Q6TA 3RO1A 1YGUA 5J8RA 2GJTA 4D3QA 4GWFA 1RXDA 3BM8A 4Y2EA 1OHCA 1BZCA 1Q6NA 1QXKA 2BV5A 4I8NA 2OZ5A 1ZC0A 4QAPA 4J51A 1XM2A 5BX1A 2PI7A 3BLTA 4NX8A 4RI5A 2SHPA 3QCDA 1NO6A 1PTUA 1OEUA 4QAHA 2QDMA 3RGQA 2F6FA 4RHGA 5KA1A 2A8BA 2I3RA 3AWEA 1C87A 2QCJA 3EU0A 2NV5A 3S4OA 1PTVA 5EHRA 2F70A 2E0TA 4KYRA 4OHHA 5K22A 2HC2A 3F99A 4RKKA 4D3RA 2HC1A 3V0IA 1YTWA 2I42A 2AZRA 2G6ZA 1BZJA 2WGPA 2J16B 3D1HA 1PH0A 3MMJA 5BUGA 2B4SA 4QUNA 3CM3A 4R30A 3EAXA 2I75A 5KABA 1T49A 1PTYA 2VEWA 2I4HA 1GFYA 1OETA 1NWEA 1YGRA 4NWGA 3S4EA 1G7FA 1FPRA 1G7GA 4ZRTA 3QKPA 2QEPA 4AZ1A 2BGDA 5K9WA 2I3UA 2I4EA 2BGEA 3EB1A 1D5RA 3B7OA 2OC3A 3QCFA 3RGOA 4PYHA 3QCIA 2VEVA 4PVGA 4H1OA 2HXPA 4JBCA 3NMEA 1Q6MA 4Y14A 2NLKA 1KAVA 1ZCLA 5KA9A 1EENA 1I9TA 3V0FA 3ZM2A 5KAAA 5KA8A 2CFVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OMH A;  2F46 A;  2PSZ A;  4H34 A;  2YDU A;  5GTJ A;  3BLU A;  1RPM A;  2PBN A;  5KAC A;  4NYH A;  3CWE A;  3ZMP A;  2ZMM A;  3GXH A;  4YAA A;  1U25 A;  2CMA A;  1WRM A;  1C86 A;  1YTS A;  2F6Y A;  3O4T A;  1PYN A;  3V0E A;  4BPC A;  2Q05 A;  1G1G A;  3MOZ A;  3O4U A;  1PA9 A;  2J17 A;  1GWZ A;  2QBR A;  4QUM A;  2NTA A;  4RI4 A;  1G1F A;  3PS5 A;  3V0D A;  4R0S A;  4RDD A;  4WOH A;  5BZZ A;  1PTT A;  3I7Z A;  4NND A;  2QBP A;  3O5X A;  3QCE A;  2ZN7 A;  2B3O A;  4S0G A;  3QCG A;  1Q6P A;  4OHL A;  1T48 A;  2CMC A;  4JNB A;  1OEV A;  1Q6S A;  3D1Q A;  2CM8 A;  3QCN A;  2I5X A;  1XRI A;  4HJQ A;  3V0H A;  1VHR A;  2M3V A;  2H02 A;  3V0G A;  3ZM1 A;  2CM2 A;  2F6T A;  4GRZ A;  1WAX A;  5K9V A;  3F41 A;  1YPT A;  1I57 A;  1YTN A;  3QCK A;  2NZ6 A;  4GE5 A;  2CM3 A;  4MBB A;  5M43 A;  1XXP A;  2I4G A;  2OOQ A;  2QCT A;  2CMB A;  1C83 A;  2GWO A;  1OES A;  3QCB A;  5KAD A;  1PXH A;  1V3A A;  2HNP A;  2P4D A;  4R0T A;  1C84 A;  3AWF A;  2VEX A;  2FJN A;  2VEU A;  1EEO A;  2AHS A;  2RF6 A;  1C85 A;  4WU3 A;  2H4G A;  4GS0 A;  2QDP A;  1I9S A;  3GXG A;  2I6I A;  2I6O A;  4QBW A;  5I6V A;  2CNH A;  2CNI A;  3V0J A;  1SUG A;  1BZH A;  4TVV A;  1C88 A;  1ONZ A;  1X24 A;  3SR9 A;  2H04 A;  2I1Y A;  2CNF A;  2H4V A;  1A5Y A;  1FQ1 A;  4KI9 A;  5KA7 A;  3F81 A;  5KA3 A;  4GFU A;  4ICZ A;  1ECV A;  3F9A A;  5AWX A;  3S3E A;  1XBO A;  1KAK A;  4DGX A;  2HVL A;  2J16 A;  1YZ4 A;  2CM7 A;  2F6V A;  4GE2 A;  3S3K A;  2GP0 A;  5IBS A;  1U26 A;  2HNQ A;  1JF7 A;  2CNE A;  4WTY A;  3I80 A;  4HRF A;  3QCM A;  3I36 A;  4OHI A;  4DGP A;  5KA0 A;  3H2X A;  2VEY A;  4ERC A;  3D1O A;  4NWF A;  4GRY A;  5K25 A;  3N0A A;  3EMU A;  2H4K A;  3EZZ A;  2HY3 A;  2NT2 A;  3O4S A;  3LJ8 A;  3OLR A;  4RH9 A;  1L8G A;  1R6H A;  1ZCK A;  4OHD A;  1PA1 A;  3MOW A;  1G4W R;  2MBC A;  3D42 A;  4KYQ A;  1WCH A;  4JMK A;  1OHD A;  5KA4 A;  2PT0 A;  2Y96 A;  1G4U S;  2R0B A;  1LAR A;  2Q47 A;  4ZN5 A;  1Q1M A;  5EHP A;  2C46 A;  3D44 A;  4GFV A;  1FPZ A;  1LQF A;  2OUD A;  1T4J A;  2I6P A;  3A5K A;  2I6J A;  4JMJ A;  2H03 A;  3AWG A;  2QBS A;  4GE6 A;  2DXP A;  2B07 A;  4YR8 B;  5K23 A;  4BJO A;  1G1H A;  4RH5 A;  2F71 A;  2QDC A;  3QCH A;  1NWL A;  2JJD A;  1YN9 A;  2ESB A;  4IKC A;  5BZX A;  1MKP A;  2P6X A;  3QCC A;  3ZM0 A;  1JLN A;  5LXQ B;  2A3K A;  2Y2F A;  2BZL A;  3SME A;  2FJM A;  2NT7 A;  1OEM X;  3QCL A;  2FH7 A;  3RZ2 A;  5IBM A;  1OEO X;  3U96 A;  2I6M A;  2F6Z A;  3QCJ A;  2CJZ A;  4ZI4 A;  4OHE A;  5KA2 A;  5MMZ B;  1U24 A;  4WU2 A;  4QBE A;  4Z6B A;  1J4X A;  2HCM A;  4HJP A;  1LYV A;  2B4U A;  1NNY A;  2C7S A;  3S3F A;  1M3G A;  1NZ7 A;  3O3L A;  1XXV A;  5K24 A;  2QBQ A;  1ZZW A;  3F9B A;  1NL9 A;  1Q6J A;  1QZ0 A;  3A5J A;  1YFO A;  2B4O A;  1P15 A;  3ZMQ A;  4B04 A;  4D3P A;  3ZM3 A;  3M4U A;  5HDE A;  2G59 A;  2CNG A;  3ZV2 A;  3D9C A;  2HB1 A;  2PQ5 A;  2PA5 A;  2IMG A;  2B49 A;  2B4P A;  3S3H A;  1OHE A;  1L8K A;  2F6W A;  1ONY A;  1AAX A;  3QKQ A;  1YWF A;  3BRH A;  2BIJ A;  1Q6T A;  3RO1 A;  1YGU A;  5J8R A;  2GJT A;  4D3Q A;  4GWF A;  1RXD A;  3BM8 A;  4Y2E A;  1OHC A;  1BZC A;  1Q6N A;  1QXK A;  2BV5 A;  4I8N A;  2OZ5 A;  1ZC0 A;  4QAP A;  4J51 A;  1XM2 A;  5BX1 A;  2PI7 A;  3BLT A;  4NX8 A;  4RI5 A;  2SHP A;  3QCD A;  1NO6 A;  1PTU A;  1OEU A;  4QAH A;  2QDM A;  3RGQ A;  2F6F A;  4RHG A;  5KA1 A;  2A8B A;  2I3R A;  3AWE A;  1C87 A;  2QCJ A;  3EU0 A;  2NV5 A;  3S4O A;  1PTV A;  5EHR A;  2F70 A;  2E0T A;  4KYR A;  4OHH A;  5K22 A;  2HC2 A;  3F99 A;  4RKK A;  4D3R A;  2HC1 A;  3V0I A;  1YTW A;  2I42 A;  2AZR A;  2G6Z A;  1BZJ A;  2WGP A;  2J16 B;  3D1H A;  1PH0 A;  3MMJ A;  5BUG A;  2B4S A;  4QUN A;  3CM3 A;  4R30 A;  3EAX A;  2I75 A;  5KAB A;  1T49 A;  1PTY A;  2VEW A;  2I4H A;  1GFY A;  1OET A;  1NWE A;  1YGR A;  4NWG A;  3S4E A;  1G7F A;  1FPR A;  1G7G A;  4ZRT A;  3QKP A;  2QEP A;  4AZ1 A;  2BGD A;  5K9W A;  2I3U A;  2I4E A;  2BGE A;  3EB1 A;  1D5R A;  3B7O A;  2OC3 A;  3QCF A;  3RGO A;  4PYH A;  3QCI A;  2VEV A;  4PVG A;  4H1O A;  2HXP A;  4JBC A;  3NME A;  1Q6M A;  4Y14 A;  2NLK A;  1KAV A;  1ZCL A;  5KA9 A;  1EEN A;  1I9T A;  3V0F A;  3ZM2 A;  5KAA A;  5KA8 A;  2CFV A; 
#chains in the Genus database with same CATH topology
 3OMH A;  2F46 A;  2PSZ A;  4H34 A;  2YDU A;  5GTJ A;  3BLU A;  1RPM A;  2PBN A;  5KAC A;  4NYH A;  3CWE A;  4C13 A;  3ZMP A;  3UAG A;  2ZMM A;  3GXH A;  4YAA A;  1U25 A;  2CMA A;  1WRM A;  1C86 A;  1YTS A;  2F6Y A;  3O4T A;  1PYN A;  3V0E A;  4BPC A;  2Q05 A;  1G1G A;  3MOZ A;  3O4U A;  1PA9 A;  2J17 A;  1GWZ A;  2QBR A;  4QUM A;  2NTA A;  2JFF A;  4RI4 A;  1G1F A;  3PS5 A;  3V0D A;  4R0S A;  4RDD A;  4WOH A;  5BZZ A;  1PTT A;  2Y1O A;  3I7Z A;  4NND A;  2QBP A;  3O5X A;  3QCE A;  2ZN7 A;  2XPC A;  2UAG A;  2B3O A;  4S0G A;  3QCG A;  1Q6P A;  1P3D A;  1T48 A;  4OHL A;  2CMC A;  3NRS A;  4JNB A;  1OEV A;  1Q6S A;  2F00 A;  3D1Q A;  2CM8 A;  3QCN A;  2I5X A;  1XRI A;  4HJQ A;  3V0H A;  1VHR A;  2M3V A;  2H02 A;  3V0G A;  3ZM1 A;  2CM2 A;  2F6T A;  4GRZ A;  1WAX A;  5K9V A;  3F41 A;  1YPT A;  1I57 A;  1YTN A;  2NZ6 A;  3QCK A;  4GE5 A;  2CM3 A;  4MBB A;  5M43 A;  1XXP A;  2I4G A;  2OOQ A;  2QCT A;  2CMB A;  1C83 A;  2GWO A;  1GQQ A;  1OES A;  3QCB A;  5KAD A;  1PXH A;  1V3A A;  2HNP A;  2P4D A;  4R0T A;  1C84 A;  3AWF A;  4QDI A;  2VEX A;  2FJN A;  2VEU A;  1EEO A;  2AHS A;  2RF6 A;  1C85 A;  4WU3 A;  2H4G A;  4GS0 A;  2JFG A;  2QDP A;  1I9S A;  3GXG A;  4CVK A;  2I6I A;  2I6O A;  4QBW A;  5I6V A;  2CNH A;  2CNI A;  3V0J A;  2AM1 A;  1SUG A;  1BZH A;  1EEH A;  5A5E A;  4TVV A;  2WTZ A;  1C88 A;  1ONZ A;  1X24 A;  3SR9 A;  2H04 A;  2I1Y A;  2CNF A;  2H4V A;  1A5Y A;  1FQ1 A;  4KI9 A;  5KA7 A;  3F81 A;  5KA3 A;  4GFU A;  4ICZ A;  1UAG A;  1ECV A;  3F9A A;  5AWX A;  3S3E A;  1XBO A;  1KAK A;  4DGX A;  2HVL A;  2J16 A;  1YZ4 A;  2CM7 A;  2JFH A;  2F6V A;  4GE2 A;  3S3K A;  2GP0 A;  5IBS A;  1U26 A;  2HNQ A;  1JF7 A;  2CNE A;  4WTY A;  3I80 A;  4HRF A;  3QCM A;  3I36 A;  4OHI A;  4DGP A;  5KA0 A;  3H2X A;  2VEY A;  2VOS A;  4ERC A;  3D1O A;  3ZM5 A;  2VTD A;  4NWF A;  4GRY A;  5K25 A;  3N0A A;  3EMU A;  2H4K A;  3EZZ A;  2HY3 A;  2NT2 A;  3O4S A;  4C12 A;  3LJ8 A;  3OLR A;  4RH9 A;  1L8G A;  1R6H A;  1ZCK A;  4OHD A;  1PA1 A;  3QCZ A;  3MOW A;  1G4W R;  2MBC A;  3D42 A;  4KYQ A;  1WCH A;  4JMK A;  1OHD A;  2UUP A;  5KA4 A;  2PT0 A;  1GG4 A;  2Y96 A;  1G4U S;  3MVN A;  4BUC A;  2XJA A;  2R0B A;  1LAR A;  1FGS A;  2Q47 A;  4ZN5 A;  1Q1M A;  5EHP A;  2WJP A;  2UUO A;  2C46 A;  3D44 A;  4GFV A;  1FPZ A;  1LQF A;  2OUD A;  1T4J A;  1GQY A;  2I6P A;  3A5K A;  2I6J A;  1E8C A;  4JMJ A;  2H03 A;  3AWG A;  2QBS A;  4GE6 A;  2DXP A;  2B07 A;  2Y67 A;  4CVM A;  4YR8 B;  5K23 A;  4BJO A;  1G1H A;  4RH5 A;  2F71 A;  2QDC A;  3QCH A;  1NWL A;  2JJD A;  1YN9 A;  2ESB A;  4IKC A;  5BZX A;  4ZIY A;  1E0D A;  1MKP A;  2P6X A;  3QCC A;  1J6U A;  3ZM0 A;  1JLN A;  5LXQ B;  2GC5 A;  2A3K A;  2Y2F A;  2BZL A;  3SME A;  2FJM A;  2NT7 A;  1OEM X;  3QCL A;  2FH7 A;  3RZ2 A;  5IBM A;  1OEO X;  1JBV A;  2GCB A;  3U96 A;  2Y68 A;  2I6M A;  2F6Z A;  3QCJ A;  2CJZ A;  4ZI4 A;  4OHE A;  5KA2 A;  5MMZ B;  1U24 A;  4WU2 A;  3ZM6 A;  4QBE A;  1O5Z A;  4Z6B A;  1J4X A;  2HCM A;  4HJP A;  1LYV A;  2B4U A;  2VOR A;  1NNY A;  2C7S A;  3S3F A;  1M3G A;  1NZ7 A;  3O3L A;  1XXV A;  5K24 A;  2QBQ A;  1ZZW A;  3F9B A;  1NL9 A;  1Q6J A;  1QZ0 A;  3A5J A;  1YFO A;  2B4O A;  1P15 A;  3ZMQ A;  4B04 A;  4D3P A;  3ZM3 A;  3M4U A;  5HDE A;  2G59 A;  2CNG A;  3ZV2 A;  3D9C A;  2HB1 A;  2PQ5 A;  2PA5 A;  2IMG A;  2B49 A;  2B4P A;  3S3H A;  1OHE A;  1L8K A;  2F6W A;  4HV4 A;  1ONY A;  1AAX A;  3QKQ A;  1YWF A;  3BRH A;  2BIJ A;  1Q6T A;  3RO1 A;  1YGU A;  5J8R A;  2GJT A;  4D3Q A;  4GWF A;  1RXD A;  2GC6 A;  3BM8 A;  3N2A A;  4Y2E A;  1OHC A;  1BZC A;  1Q6N A;  2AM2 A;  2Y66 A;  1QXK A;  2BV5 A;  4I8N A;  2OZ5 A;  1ZC0 A;  4QAP A;  4CVL A;  1JBW A;  4J51 A;  1XM2 A;  5BX1 A;  2PI7 A;  3BLT A;  4NX8 A;  4RI5 A;  2SHP A;  3QCD A;  3ZL8 A;  2VTE A;  1NO6 A;  2GCA A;  1PTU A;  1OEU A;  4QAH A;  2QDM A;  3RGQ A;  2F6F A;  4RHG A;  5KA1 A;  2A8B A;  2I3R A;  3AWE A;  1C87 A;  2QCJ A;  3EU0 A;  2NV5 A;  3S4O A;  1PTV A;  5EHR A;  2F70 A;  2E0T A;  3HN7 A;  5A5F A;  4KYR A;  4OHH A;  5K22 A;  2HC2 A;  3F99 A;  4RKK A;  4D3R A;  2HC1 A;  3V0I A;  1YTW A;  2I42 A;  2AZR A;  2G6Z A;  1BZJ A;  4QF5 A;  2WGP A;  2J16 B;  3D1H A;  1PH0 A;  3MMJ A;  5BUG A;  2B4S A;  4QUN A;  3CM3 A;  3PYZ A;  4R30 A;  4BUB A;  3EAX A;  4UAG A;  2I75 A;  5KAB A;  1T49 A;  1PTY A;  2VEW A;  2I4H A;  1GFY A;  1OET A;  1W78 A;  1NWE A;  1YGR A;  4NWG A;  3S4E A;  1G7F A;  1FPR A;  1G7G A;  4ZRT A;  3QKP A;  2QEP A;  4AZ1 A;  2BGD A;  5K9W A;  2I3U A;  2I4E A;  2BGE A;  3EB1 A;  1D5R A;  3B7O A;  2OC3 A;  3QCF A;  3RGO A;  1P31 A;  4PYH A;  3QCI A;  2VEV A;  4PVG A;  3LK7 A;  4H1O A;  2HXP A;  4JBC A;  3NME A;  1Q6M A;  4Y14 A;  2NLK A;  1KAV A;  2X5O A;  1ZCL A;  5KA9 A;  1EEN A;  1I9T A;  3V0F A;  1W7K A;  3ZM2 A;  5KA8 A;  5KAA A;  2CFV A; 
#chains in the Genus database with same CATH homology
 3OMH A;  2F46 A;  2PSZ A;  4H34 A;  2YDU A;  5GTJ A;  3BLU A;  1RPM A;  2PBN A;  5KAC A;  4NYH A;  3CWE A;  3ZMP A;  2ZMM A;  3GXH A;  4YAA A;  1U25 A;  2CMA A;  1WRM A;  1C86 A;  1YTS A;  2F6Y A;  3O4T A;  1PYN A;  3V0E A;  4BPC A;  2Q05 A;  1G1G A;  3MOZ A;  3O4U A;  1PA9 A;  2J17 A;  1GWZ A;  2QBR A;  4QUM A;  2NTA A;  4RI4 A;  1G1F A;  3PS5 A;  3V0D A;  4R0S A;  4RDD A;  4WOH A;  5BZZ A;  1PTT A;  3I7Z A;  4NND A;  2QBP A;  3O5X A;  3QCE A;  2ZN7 A;  2B3O A;  4S0G A;  3QCG A;  1Q6P A;  4OHL A;  1T48 A;  2CMC A;  4JNB A;  1OEV A;  1Q6S A;  3D1Q A;  2CM8 A;  3QCN A;  2I5X A;  1XRI A;  4HJQ A;  3V0H A;  1VHR A;  2M3V A;  2H02 A;  3V0G A;  3ZM1 A;  2CM2 A;  2F6T A;  4GRZ A;  1WAX A;  5K9V A;  3F41 A;  1YPT A;  1I57 A;  1YTN A;  3QCK A;  2NZ6 A;  4GE5 A;  2CM3 A;  4MBB A;  5M43 A;  1XXP A;  2I4G A;  2OOQ A;  2QCT A;  2CMB A;  1C83 A;  2GWO A;  1OES A;  3QCB A;  5KAD A;  1PXH A;  1V3A A;  2HNP A;  2P4D A;  4R0T A;  1C84 A;  3AWF A;  2VEX A;  2FJN A;  2VEU A;  1EEO A;  2AHS A;  2RF6 A;  1C85 A;  4WU3 A;  2H4G A;  4GS0 A;  2QDP A;  1I9S A;  3GXG A;  2I6I A;  2I6O A;  4QBW A;  5I6V A;  2CNH A;  2CNI A;  3V0J A;  1SUG A;  1BZH A;  4TVV A;  1C88 A;  1ONZ A;  1X24 A;  3SR9 A;  2H04 A;  2I1Y A;  2CNF A;  2H4V A;  1A5Y A;  1FQ1 A;  4KI9 A;  5KA7 A;  3F81 A;  5KA3 A;  4GFU A;  4ICZ A;  1ECV A;  3F9A A;  5AWX A;  3S3E A;  1XBO A;  1KAK A;  4DGX A;  2HVL A;  2J16 A;  1YZ4 A;  2CM7 A;  2F6V A;  4GE2 A;  3S3K A;  2GP0 A;  5IBS A;  1U26 A;  2HNQ A;  1JF7 A;  2CNE A;  4WTY A;  3I80 A;  4HRF A;  3QCM A;  3I36 A;  4OHI A;  4DGP A;  5KA0 A;  3H2X A;  2VEY A;  4ERC A;  3D1O A;  4NWF A;  4GRY A;  5K25 A;  3N0A A;  3EMU A;  2H4K A;  3EZZ A;  2HY3 A;  2NT2 A;  3O4S A;  3LJ8 A;  3OLR A;  4RH9 A;  1L8G A;  1R6H A;  1ZCK A;  4OHD A;  1PA1 A;  3MOW A;  1G4W R;  2MBC A;  3D42 A;  4KYQ A;  1WCH A;  4JMK A;  1OHD A;  5KA4 A;  2PT0 A;  2Y96 A;  1G4U S;  2R0B A;  1LAR A;  2Q47 A;  4ZN5 A;  1Q1M A;  5EHP A;  2C46 A;  3D44 A;  4GFV A;  1FPZ A;  1LQF A;  2OUD A;  1T4J A;  2I6P A;  3A5K A;  2I6J A;  4JMJ A;  2H03 A;  3AWG A;  2QBS A;  4GE6 A;  2DXP A;  2B07 A;  4YR8 B;  5K23 A;  4BJO A;  1G1H A;  4RH5 A;  2F71 A;  2QDC A;  3QCH A;  1NWL A;  2JJD A;  1YN9 A;  2ESB A;  4IKC A;  5BZX A;  1MKP A;  2P6X A;  3QCC A;  3ZM0 A;  1JLN A;  5LXQ B;  2A3K A;  2Y2F A;  2BZL A;  3SME A;  2FJM A;  2NT7 A;  1OEM X;  3QCL A;  2FH7 A;  3RZ2 A;  5IBM A;  1OEO X;  3U96 A;  2I6M A;  2F6Z A;  3QCJ A;  2CJZ A;  4ZI4 A;  4OHE A;  5KA2 A;  5MMZ B;  1U24 A;  4WU2 A;  4QBE A;  4Z6B A;  1J4X A;  2HCM A;  4HJP A;  1LYV A;  2B4U A;  1NNY A;  2C7S A;  3S3F A;  1M3G A;  1NZ7 A;  3O3L A;  1XXV A;  5K24 A;  2QBQ A;  1ZZW A;  3F9B A;  1NL9 A;  1Q6J A;  1QZ0 A;  3A5J A;  1YFO A;  2B4O A;  1P15 A;  3ZMQ A;  4B04 A;  4D3P A;  3ZM3 A;  3M4U A;  5HDE A;  2G59 A;  2CNG A;  3ZV2 A;  3D9C A;  2HB1 A;  2PQ5 A;  2PA5 A;  2IMG A;  2B49 A;  2B4P A;  3S3H A;  1OHE A;  1L8K A;  2F6W A;  1ONY A;  1AAX A;  3QKQ A;  1YWF A;  3BRH A;  2BIJ A;  1Q6T A;  3RO1 A;  1YGU A;  5J8R A;  2GJT A;  4D3Q A;  4GWF A;  1RXD A;  3BM8 A;  4Y2E A;  1OHC A;  1BZC A;  1Q6N A;  1QXK A;  2BV5 A;  4I8N A;  2OZ5 A;  1ZC0 A;  4QAP A;  4J51 A;  1XM2 A;  5BX1 A;  2PI7 A;  3BLT A;  4NX8 A;  4RI5 A;  2SHP A;  3QCD A;  1NO6 A;  1PTU A;  1OEU A;  4QAH A;  2QDM A;  3RGQ A;  2F6F A;  4RHG A;  5KA1 A;  2A8B A;  2I3R A;  3AWE A;  1C87 A;  2QCJ A;  3EU0 A;  2NV5 A;  3S4O A;  1PTV A;  5EHR A;  2F70 A;  2E0T A;  4KYR A;  4OHH A;  5K22 A;  2HC2 A;  3F99 A;  4RKK A;  4D3R A;  2HC1 A;  3V0I A;  1YTW A;  2I42 A;  2AZR A;  2G6Z A;  1BZJ A;  2WGP A;  2J16 B;  3D1H A;  1PH0 A;  3MMJ A;  5BUG A;  2B4S A;  4QUN A;  3CM3 A;  4R30 A;  3EAX A;  2I75 A;  5KAB A;  1T49 A;  1PTY A;  2VEW A;  2I4H A;  1GFY A;  1OET A;  1NWE A;  1YGR A;  4NWG A;  3S4E A;  1G7F A;  1FPR A;  1G7G A;  4ZRT A;  3QKP A;  2QEP A;  4AZ1 A;  2BGD A;  5K9W A;  2I3U A;  2I4E A;  2BGE A;  3EB1 A;  1D5R A;  3B7O A;  2OC3 A;  3QCF A;  3RGO A;  4PYH A;  3QCI A;  2VEV A;  4PVG A;  4H1O A;  2HXP A;  4JBC A;  3NME A;  1Q6M A;  4Y14 A;  2NLK A;  1KAV A;  1ZCL A;  5KA9 A;  1EEN A;  1I9T A;  3V0F A;  3ZM2 A;  5KAA A;  5KA8 A;  2CFV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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