5KADA

Protein tyrosine phosphatase 1b n193a mutant in complex with tcs401, closed state
Total Genus 100
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
285
structure length
285
Chain Sequence
HMASMEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLAFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
total genus 100
structure length 285
sequence length 285
chains with identical sequence B
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2016-06-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 5kadA00
4KYRA 5IBSA 3D1OA 4NX8A 3N0AA 3EB1A 2HVLA 4BPCA 2PQ5A 1Q6MA 3I36A 5BX1A 1Q6PA 4RKKA 4DGPA 5EHPA 3BLUA 3QCCA 1PYNA 1KAVA 2VEYA 2ZN7A 4J51A 1ECVA 2GP0A 2H04A 1P15A 2P6XA 3QCJA 1VHRA 4ICZA 4WTYA 2VEXA 1YGUA 3S4EA 2CM8A 1I57A 5K23A 2IMGA 1NWEA 2HNPA 5KA2A 1XRIA 3QCMA 4WU3A 4GRYA 4RHGA 4BJOA 2F70A 1G1FA 1PA9A 3EAXA 2B4UA 4JMKA 1WRMA 2G6ZA 1YTWA 3B7OA 2A8BA 2M3VA 2CFVA 2HCMA 3D1QA 4AZ1A 1PTUA 2B4OA 1YZ4A 2I4GA 3V0HA 4Y2EA 4OHIA 1PA1A 5KA8A 3RGQA 4RI4A 2ESBA 2CM2A 2CMBA 3AWEA 3QCGA 2BZLA 4HJPA 2PT0A 1EENA 2CMAA 1T49A 3S3KA 1FQ1A 2CMCA 1V3AA 1Q6JA 2J17A 3O4SA 4QAHA 1JLNA 3SMEA 2J16B 4ERCA 3CWEA 4PVGA 3V0FA 2GJTA 4WU2A 5KADA 3F9AA 2CNFA 2WGPA 5GTJA 2H4KA 3GXHA 1C88A 3BM8A 3EZZA 1G1HA 2VEVA 2B3OA 3QCLA 3I80A 4GE6A 2CNHA 1G4US 4HRFA 5K9WA 3ZMPA 4QBWA 5BZXA 2PA5A 2R0BA 3MMJA 2Q47A 3QKQA 4D3QA 2C7SA 2HC2A 2CJZA 3D9CA 1M3GA 3QCIA 1OEUA 1ZCLA 2QCJA 1U24A 2NLKA 5K9VA 2NT7A 2I6PA 4NWGA 2I42A 2I5XA 2QBPA 3F9BA 3S3HA 2OC3A 1A5YA 1J4XA 2FJNA 3OMHA 5K22A 1PH0A 4GS0A 2BV5A 2F6TA 1G1GA 2PBNA 4PYHA 2GWOA 2QCTA 4RI5A 3NMEA 4NYHA 4R30A 2B49A 2OOQA 2J16A 4OHEA 3EU0A 4KI9A 2QBRA 3QKPA 1G7FA 3F41A 4YAAA 4Y14A 1OHCA 3M4UA 1NL9A 4OHLA 1SUGA 3CM3A 4QBEA 2F6VA 1XM2A 5M43A 2B07A 4ZRTA 1U25A 5KA3A 4DGXA 4GE5A 2PI7A 4GFVA 1GFYA 1QZ0A 2NT2A 2FJMA 4S0GA 1XXPA 5KA7A 1JF7A 2F46A 3QCEA 4B04A 5IBMA 1YWFA 5K25A 1NNYA 1WAXA 2OUDA 1C86A 3BLTA 4GRZA 3V0EA 1OEVA 2HNQA 1OETA 1NO6A 3V0JA 3EMUA 1WCHA 1L8GA 2I6OA 2QDPA 3V0IA 1C84A 5BUGA 4OHHA 1YPTA 1R6HA 5AWXA 2I3RA 2FH7A 2I6JA 1RXDA 1D5RA 2NTAA 3ZM1A 3SR9A 1OEOX 3QCKA 1PTYA 1YGRA 1ZC0A 3QCNA 1BZCA 1EEOA 4H34A 5J8RA 3F81A 3LJ8A 4QUMA 2I6IA 2ZMMA 3BRHA 2CM3A 1G4WR 2BIJA 3O4TA 3ZV2A 2F6WA 5HDEA 5MMZB 1Q6TA 5KACA 2CNEA 5K24A 3ZMQA 5KABA 2I4EA 2MBCA 3ZM0A 1FPRA 3V0DA 3O4UA 1YN9A 2QBQA 3S3EA 1YFOA 1OHDA 1Q6SA 2AHSA 1LYVA 2OZ5A 5I6VA 2HY3A 2CNGA 1C87A 2I75A 2E0TA 1ONZA 1LARA 2HB1A 1OESA 2I6MA 4GE2A 5KAAA 1BZHA 1ZZWA 2I1YA 5LXQB 1BZJA 1ONYA 1Q6NA 2DXPA 2I3UA 3I7ZA 2H02A 3F99A 3QCFA 5BZZA 3AWFA 3D1HA 2QEPA 3D44A 2B4SA 3S4OA 3RO1A 2VEUA 3A5JA 4NNDA 4NWFA 2SHPA 1G7GA 4RH5A 2JJDA 4JNBA 2QDMA 3PS5A 4I8NA 1MKPA 1YTNA 3QCDA 3GXGA 3ZM3A 1T48A 2G59A 1RPMA 4H1OA 3S3FA 1I9SA 2PSZA 2NZ6A 1Q1MA 4TVVA 3RGOA 3H2XA 5KA1A 4WOHA 4OHDA 4D3RA 3U96A 2BGDA 4QUNA 2HC1A 4D3PA 4R0SA 5KA9A 4JBCA 4RDDA 4QAPA 5KA4A 3QCBA 2CM7A 1NZ7A 2F71A 1LQFA 1KAKA 1PXHA 2VEWA 2H4GA 2Y2FA 1I9TA 4IKCA 3D42A 3OLRA 1C83A 1YTSA 1QXKA 2H4VA 3O5XA 4GWFA 2QDCA 4HJQA 4MBBA 1L8KA 2C46A 3A5KA 2AZRA 5EHRA 2NV5A 1PTTA 2Y96A 3RZ2A 3O3LA 1FPZA 2H03A 1U26A 3MOZA 3ZM2A 2RF6A 2P4DA 4R0TA 4ZI4A 2B4PA 2BGEA 5KA0A 3AWGA 4GFUA 2HXPA 1OEMX 4Z6BA 1GWZA 4RH9A 2QBSA 4YR8B 1XXVA 2F6YA 4ZN5A 1XBOA 1T4JA 2YDUA 2CNIA 1ZCKA 1AAXA 2I4HA 4KYQA 4JMJA 1OHEA 2Q05A 1X24A 1C85A 2F6ZA 1NWLA 1PTVA 3MOWA 3V0GA 2F6FA 2A3KA 3QCHA
chains in the Genus database with same CATH superfamily
2UUOA 4KYRA 5IBSA 3D1OA 4NX8A 3N0AA 3EB1A 2HVLA 3ZL8A 1GQQA 4BPCA 1P31A 1EEHA 2PQ5A 1E0DA 4QDIA 1Q6MA 3I36A 5BX1A 2F00A 1Q6PA 4RKKA 4DGPA 5EHPA 3BLUA 3QCCA 1PYNA 1KAVA 1UAGA 2VEYA 2ZN7A 4J51A 1ECVA 1O5ZA 2GP0A 2H04A 1P15A 1JBVA 2P6XA 3QCJA 1VHRA 4ICZA 2WJPA 4WTYA 2VEXA 1YGUA 3S4EA 2CM8A 1I57A 5K23A 2IMGA 1NWEA 2HNPA 5KA2A 1XRIA 3QCMA 4WU3A 4GRYA 4RHGA 4BJOA 2F70A 1G1FA 1PA9A 3EAXA 2B4UA 4JMKA 4QF5A 2G6ZA 1YTWA 3B7OA 2A8BA 2M3VA 2CFVA 2HCMA 3D1QA 4AZ1A 3ZM5A 1PTUA 2B4OA 1YZ4A 2I4GA 3V0HA 2X5OA 4Y2EA 4OHIA 1PA1A 5KA8A 1P3DA 3RGQA 4RI4A 2XPCA 2ESBA 1GQYA 2Y1OA 2CM2A 2CMBA 3AWEA 3QCGA 2BZLA 4HJPA 2PT0A 1EENA 2CMAA 1T49A 3S3KA 1FQ1A 2CMCA 1V3AA 3PYZA 1Q6JA 2J17A 3O4SA 4QAHA 1JLNA 3SMEA 2J16B 4ERCA 3CWEA 4PVGA 3V0FA 2GJTA 4WU2A 5KADA 3F9AA 2CNFA 4BUCA 2WGPA 5GTJA 2H4KA 3GXHA 1C88A 3NRSA 3BM8A 3EZZA 1G1HA 2VEVA 2B3OA 2Y67A 3QCLA 3I80A 4GE6A 2CNHA 1G4US 4HRFA 5K9WA 3ZMPA 4QBWA 1W7KA 2PA5A 2R0BA 3MMJA 5BZXA 2Q47A 3QKQA 4D3QA 2C7SA 2HC2A 2CJZA 3D9CA 1M3GA 3QCIA 1OEUA 1ZCLA 2QCJA 1U24A 2WTZA 2NLKA 5K9VA 2NT7A 2I6PA 2AM1A 4NWGA 2GC5A 2I42A 2I5XA 2QBPA 3F9BA 2VTEA 2OC3A 1A5YA 1J4XA 2FJNA 3OMHA 5K22A 3S3HA 1PH0A 4GS0A 2BV5A 2F6TA 1G1GA 2PBNA 4PYHA 2GWOA 2QCTA 4RI5A 3NMEA 4NYHA 4R30A 2B49A 2OOQA 2J16A 4OHEA 3EU0A 4KI9A 2QBRA 3QKPA 1G7FA 3F41A 4YAAA 4Y14A 1OHCA 3M4UA 1W78A 1NL9A 4OHLA 1SUGA 3CM3A 4QBEA 2F6VA 1XM2A 5M43A 2B07A 4ZRTA 1U25A 5KA3A 4DGXA 4GE5A 2PI7A 4GFVA 2JFGA 1GFYA 2VORA 1QZ0A 2NT2A 2FJMA 2Y68A 4S0GA 1FGSA 1XXPA 5KA7A 1JF7A 2F46A 3QCEA 4B04A 5IBMA 1YWFA 3QCZA 5K25A 1NNYA 1WAXA 2OUDA 1C86A 3BLTA 4GRZA 3V0EA 1OEVA 2HNQA 3UAGA 2JFHA 1OETA 1NO6A 3V0JA 3EMUA 1WCHA 1L8GA 2I6OA 2QDPA 3V0IA 1C84A 5BUGA 4OHHA 2JFFA 1YPTA 1R6HA 5AWXA 2I3RA 2Y66A 2FH7A 2I6JA 1RXDA 1D5RA 2NTAA 4CVKA 3ZM1A 3SR9A 1OEOX 3QCKA 1PTYA 1YGRA 1ZC0A 3QCNA 3ZM6A 1BZCA 1EEOA 4H34A 5J8RA 3F81A 3LJ8A 4QUMA 1J6UA 2I6IA 2ZMMA 3BRHA 2CM3A 1G4WR 2BIJA 5A5FA 3O4TA 3ZV2A 2F6WA 5HDEA 5MMZB 1JBWA 4CVMA 1Q6TA 5KACA 2CNEA 5K24A 3ZMQA 5KABA 2I4EA 2MBCA 3ZM0A 1FPRA 3V0DA 3O4UA 1YN9A 2QBQA 3S3EA 1YFOA 1OHDA 1Q6SA 3MVNA 3LK7A 2AHSA 1LYVA 2OZ5A 5I6VA 2AM2A 2HY3A 2CNGA 2XJAA 1C87A 2I75A 2E0TA 1ONZA 1LARA 4C12A 2HB1A 1OESA 2I6MA 4GE2A 5KAAA 1BZHA 1ZZWA 2I1YA 5LXQB 1BZJA 1ONYA 1Q6NA 2DXPA 2I3UA 2GC6A 3I7ZA 2H02A 3F99A 3QCFA 5BZZA 3AWFA 3D1HA 2UUPA 2QEPA 3D44A 2B4SA 3S4OA 3RO1A 2VEUA 3A5JA 4NNDA 4NWFA 2SHPA 1G7GA 4RH5A 2JJDA 3HN7A 4JNBA 2QDMA 4C13A 3PS5A 4I8NA 1MKPA 1YTNA 3QCDA 3GXGA 3ZM3A 1T48A 2G59A 1RPMA 4UAGA 4H1OA 3S3FA 1I9SA 2PSZA 2NZ6A 1Q1MA 4TVVA 3RGOA 3H2XA 5A5EA 5KA1A 4WOHA 4OHDA 4D3RA 3U96A 2BGDA 4QUNA 2HC1A 3QCHA 4D3PA 4R0SA 4BUBA 5KA9A 1GG4A 4JBCA 4RDDA 4QAPA 5KA4A 3QCBA 2CM7A 1NZ7A 2F71A 1LQFA 1KAKA 1PXHA 2VEWA 4HV4A 2H4GA 2Y2FA 2GCAA 1I9TA 4IKCA 3D42A 3OLRA 1C83A 1YTSA 4CVLA 1QXKA 2H4VA 3O5XA 4GWFA 2QDCA 4HJQA 4MBBA 1L8KA 2C46A 3A5KA 2AZRA 5EHRA 2NV5A 1PTTA 2Y96A 3RZ2A 3O3LA 1FPZA 2H03A 1U26A 3MOZA 3ZM2A 2RF6A 2P4DA 4R0TA 4ZI4A 2B4PA 2BGEA 5KA0A 3AWGA 4GFUA 2HXPA 1OEMX 4Z6BA 1GWZA 4RH9A 4ZIYA 2QBSA 2VTDA 4YR8B 1XXVA 2F6YA 2UAGA 1XBOA 1T4JA 4ZN5A 2YDUA 2CNIA 1ZCKA 1AAXA 2I4HA 2VOSA 4KYQA 4JMJA 1OHEA 2GCBA 2Q05A 1X24A 1C85A 2F6ZA 1NWLA 1PTVA 3MOWA 1E8CA 3N2AA 3V0GA 2F6FA 2A3KA 1WRMA
chains in the Genus database with same CATH topology
4KYRA 5IBSA 3D1OA 4NX8A 3N0AA 3EB1A 2HVLA 4BPCA 2PQ5A 1Q6MA 3I36A 5BX1A 1Q6PA 4RKKA 4DGPA 5EHPA 3BLUA 3QCCA 1PYNA 1KAVA 2VEYA 2ZN7A 4J51A 1ECVA 2GP0A 2H04A 1P15A 2P6XA 3QCJA 1VHRA 4ICZA 4WTYA 2VEXA 1YGUA 3S4EA 2CM8A 1I57A 5K23A 2IMGA 1NWEA 2HNPA 5KA2A 1XRIA 3QCMA 4WU3A 4GRYA 4RHGA 4BJOA 2F70A 1G1FA 1PA9A 3EAXA 2B4UA 4JMKA 1WRMA 2G6ZA 1YTWA 3B7OA 2A8BA 2M3VA 2CFVA 2HCMA 3D1QA 4AZ1A 1PTUA 2B4OA 1YZ4A 2I4GA 3V0HA 4Y2EA 4OHIA 1PA1A 5KA8A 3RGQA 4RI4A 2ESBA 2CM2A 2CMBA 3AWEA 3QCGA 2BZLA 4HJPA 2PT0A 1EENA 2CMAA 1T49A 3S3KA 1FQ1A 2CMCA 1V3AA 1Q6JA 2J17A 3O4SA 4QAHA 1JLNA 3SMEA 2J16B 4ERCA 3CWEA 4PVGA 3V0FA 2GJTA 4WU2A 5KADA 3F9AA 2CNFA 2WGPA 5GTJA 2H4KA 3GXHA 1C88A 3BM8A 3EZZA 1G1HA 2VEVA 2B3OA 3QCLA 3I80A 4GE6A 2CNHA 1G4US 4HRFA 5K9WA 3ZMPA 4QBWA 5BZXA 2PA5A 2R0BA 3MMJA 2Q47A 3QKQA 4D3QA 2C7SA 2HC2A 2CJZA 3D9CA 1M3GA 3QCIA 1OEUA 1ZCLA 2QCJA 1U24A 2NLKA 5K9VA 2NT7A 2I6PA 4NWGA 2I42A 2I5XA 2QBPA 3F9BA 3S3HA 2OC3A 1A5YA 1J4XA 2FJNA 3OMHA 5K22A 1PH0A 4GS0A 2BV5A 2F6TA 1G1GA 2PBNA 4PYHA 2GWOA 2QCTA 4RI5A 3NMEA 4NYHA 4R30A 2B49A 2OOQA 2J16A 4OHEA 3EU0A 4KI9A 2QBRA 3QKPA 1G7FA 3F41A 4YAAA 4Y14A 1OHCA 3M4UA 1NL9A 4OHLA 1SUGA 3CM3A 4QBEA 2F6VA 1XM2A 5M43A 2B07A 4ZRTA 1U25A 5KA3A 4DGXA 4GE5A 2PI7A 4GFVA 1GFYA 1QZ0A 2NT2A 2FJMA 4S0GA 1XXPA 5KA7A 1JF7A 2F46A 3QCEA 4B04A 5IBMA 1YWFA 5K25A 1NNYA 1WAXA 2OUDA 1C86A 3BLTA 4GRZA 3V0EA 1OEVA 2HNQA 1OETA 1NO6A 3V0JA 3EMUA 1WCHA 1L8GA 2I6OA 2QDPA 3V0IA 1C84A 5BUGA 4OHHA 1YPTA 1R6HA 5AWXA 2I3RA 2FH7A 2I6JA 1RXDA 1D5RA 2NTAA 3ZM1A 3SR9A 1OEOX 3QCKA 1PTYA 1YGRA 1ZC0A 3QCNA 1BZCA 1EEOA 4H34A 5J8RA 3F81A 3LJ8A 4QUMA 2I6IA 2ZMMA 3BRHA 2CM3A 1G4WR 2BIJA 3O4TA 3ZV2A 2F6WA 5HDEA 5MMZB 1Q6TA 5KACA 2CNEA 5K24A 3ZMQA 5KABA 2I4EA 2MBCA 3ZM0A 1FPRA 3V0DA 3O4UA 1YN9A 2QBQA 3S3EA 1YFOA 1OHDA 1Q6SA 2AHSA 1LYVA 2OZ5A 5I6VA 2HY3A 2CNGA 1C87A 2I75A 2E0TA 1ONZA 1LARA 2HB1A 1OESA 2I6MA 4GE2A 5KAAA 1BZHA 1ZZWA 2I1YA 5LXQB 1BZJA 1ONYA 1Q6NA 2DXPA 2I3UA 3I7ZA 2H02A 3F99A 3QCFA 5BZZA 3AWFA 3D1HA 2QEPA 3D44A 2B4SA 3S4OA 3RO1A 2VEUA 3A5JA 4NNDA 4NWFA 2SHPA 1G7GA 4RH5A 2JJDA 4JNBA 2QDMA 3PS5A 4I8NA 1MKPA 1YTNA 3QCDA 3GXGA 3ZM3A 1T48A 2G59A 1RPMA 4H1OA 3S3FA 1I9SA 2PSZA 2NZ6A 1Q1MA 4TVVA 3RGOA 3H2XA 5KA1A 4WOHA 4OHDA 4D3RA 3U96A 2BGDA 4QUNA 2HC1A 4D3PA 4R0SA 5KA9A 4JBCA 4RDDA 4QAPA 5KA4A 3QCBA 2CM7A 1NZ7A 2F71A 1LQFA 1KAKA 1PXHA 2VEWA 2H4GA 2Y2FA 1I9TA 4IKCA 3D42A 3OLRA 1C83A 1YTSA 1QXKA 2H4VA 3O5XA 4GWFA 2QDCA 4HJQA 4MBBA 1L8KA 2C46A 3A5KA 2AZRA 5EHRA 2NV5A 1PTTA 2Y96A 3RZ2A 3O3LA 1FPZA 2H03A 1U26A 3MOZA 3ZM2A 2RF6A 2P4DA 4R0TA 4ZI4A 2B4PA 2BGEA 5KA0A 3AWGA 4GFUA 2HXPA 1OEMX 4Z6BA 1GWZA 4RH9A 2QBSA 4YR8B 1XXVA 2F6YA 4ZN5A 1XBOA 1T4JA 2YDUA 2CNIA 1ZCKA 1AAXA 2I4HA 4KYQA 4JMJA 1OHEA 2Q05A 1X24A 1C85A 2F6ZA 1NWLA 1PTVA 3MOWA 3V0GA 2F6FA 2A3KA 3QCHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KYR A;  5IBS A;  3D1O A;  4NX8 A;  3N0A A;  3EB1 A;  2HVL A;  4BPC A;  2PQ5 A;  1Q6M A;  3I36 A;  5BX1 A;  1Q6P A;  4RKK A;  4DGP A;  5EHP A;  3BLU A;  3QCC A;  1PYN A;  1KAV A;  2VEY A;  2ZN7 A;  4J51 A;  1ECV A;  2GP0 A;  2H04 A;  1P15 A;  2P6X A;  3QCJ A;  1VHR A;  4ICZ A;  4WTY A;  2VEX A;  1YGU A;  3S4E A;  2CM8 A;  1I57 A;  5K23 A;  2IMG A;  1NWE A;  2HNP A;  5KA2 A;  1XRI A;  3QCM A;  4WU3 A;  4GRY A;  4RHG A;  4BJO A;  2F70 A;  1G1F A;  1PA9 A;  3EAX A;  2B4U A;  4JMK A;  1WRM A;  2G6Z A;  1YTW A;  3B7O A;  2A8B A;  2M3V A;  2CFV A;  2HCM A;  3D1Q A;  4AZ1 A;  1PTU A;  2B4O A;  1YZ4 A;  2I4G A;  3V0H A;  4Y2E A;  4OHI A;  1PA1 A;  5KA8 A;  3RGQ A;  4RI4 A;  2ESB A;  2CM2 A;  2CMB A;  3AWE A;  3QCG A;  2BZL A;  4HJP A;  2PT0 A;  1EEN A;  2CMA A;  1T49 A;  3S3K A;  1FQ1 A;  2CMC A;  1V3A A;  1Q6J A;  2J17 A;  3O4S A;  4QAH A;  1JLN A;  3SME A;  2J16 B;  4ERC A;  3CWE A;  4PVG A;  3V0F A;  2GJT A;  4WU2 A;  5KAD A;  3F9A A;  2CNF A;  2WGP A;  5GTJ A;  2H4K A;  3GXH A;  1C88 A;  3BM8 A;  3EZZ A;  1G1H A;  2VEV A;  2B3O A;  3QCL A;  3I80 A;  4GE6 A;  2CNH A;  1G4U S;  4HRF A;  5K9W A;  3ZMP A;  4QBW A;  5BZX A;  2PA5 A;  2R0B A;  3MMJ A;  2Q47 A;  3QKQ A;  4D3Q A;  2C7S A;  2HC2 A;  2CJZ A;  3D9C A;  1M3G A;  3QCI A;  1OEU A;  1ZCL A;  2QCJ A;  1U24 A;  2NLK A;  5K9V A;  2NT7 A;  2I6P A;  4NWG A;  2I42 A;  2I5X A;  2QBP A;  3F9B A;  3S3H A;  2OC3 A;  1A5Y A;  1J4X A;  2FJN A;  3OMH A;  5K22 A;  1PH0 A;  4GS0 A;  2BV5 A;  2F6T A;  1G1G A;  2PBN A;  4PYH A;  2GWO A;  2QCT A;  4RI5 A;  3NME A;  4NYH A;  4R30 A;  2B49 A;  2OOQ A;  2J16 A;  4OHE A;  3EU0 A;  4KI9 A;  2QBR A;  3QKP A;  1G7F A;  3F41 A;  4YAA A;  4Y14 A;  1OHC A;  3M4U A;  1NL9 A;  4OHL A;  1SUG A;  3CM3 A;  4QBE A;  2F6V A;  1XM2 A;  5M43 A;  2B07 A;  4ZRT A;  1U25 A;  5KA3 A;  4DGX A;  4GE5 A;  2PI7 A;  4GFV A;  1GFY A;  1QZ0 A;  2NT2 A;  2FJM A;  4S0G A;  1XXP A;  5KA7 A;  1JF7 A;  2F46 A;  3QCE A;  4B04 A;  5IBM A;  1YWF A;  5K25 A;  1NNY A;  1WAX A;  2OUD A;  1C86 A;  3BLT A;  4GRZ A;  3V0E A;  1OEV A;  2HNQ A;  1OET A;  1NO6 A;  3V0J A;  3EMU A;  1WCH A;  1L8G A;  2I6O A;  2QDP A;  3V0I A;  1C84 A;  5BUG A;  4OHH A;  1YPT A;  1R6H A;  5AWX A;  2I3R A;  2FH7 A;  2I6J A;  1RXD A;  1D5R A;  2NTA A;  3ZM1 A;  3SR9 A;  1OEO X;  3QCK A;  1PTY A;  1YGR A;  1ZC0 A;  3QCN A;  1BZC A;  1EEO A;  4H34 A;  5J8R A;  3F81 A;  3LJ8 A;  4QUM A;  2I6I A;  2ZMM A;  3BRH A;  2CM3 A;  1G4W R;  2BIJ A;  3O4T A;  3ZV2 A;  2F6W A;  5HDE A;  5MMZ B;  1Q6T A;  5KAC A;  2CNE A;  5K24 A;  3ZMQ A;  5KAB A;  2I4E A;  2MBC A;  3ZM0 A;  1FPR A;  3V0D A;  3O4U A;  1YN9 A;  2QBQ A;  3S3E A;  1YFO A;  1OHD A;  1Q6S A;  2AHS A;  1LYV A;  2OZ5 A;  5I6V A;  2HY3 A;  2CNG A;  1C87 A;  2I75 A;  2E0T A;  1ONZ A;  1LAR A;  2HB1 A;  1OES A;  2I6M A;  4GE2 A;  5KAA A;  1BZH A;  1ZZW A;  2I1Y A;  5LXQ B;  1BZJ A;  1ONY A;  1Q6N A;  2DXP A;  2I3U A;  3I7Z A;  2H02 A;  3F99 A;  3QCF A;  5BZZ A;  3AWF A;  3D1H A;  2QEP A;  3D44 A;  2B4S A;  3S4O A;  3RO1 A;  2VEU A;  3A5J A;  4NND A;  4NWF A;  2SHP A;  1G7G A;  4RH5 A;  2JJD A;  4JNB A;  2QDM A;  3PS5 A;  4I8N A;  1MKP A;  1YTN A;  3QCD A;  3GXG A;  3ZM3 A;  1T48 A;  2G59 A;  1RPM A;  4H1O A;  3S3F A;  1I9S A;  2PSZ A;  2NZ6 A;  1Q1M A;  4TVV A;  3RGO A;  3H2X A;  5KA1 A;  4WOH A;  4OHD A;  4D3R A;  3U96 A;  2BGD A;  4QUN A;  2HC1 A;  4D3P A;  4R0S A;  5KA9 A;  4JBC A;  4RDD A;  4QAP A;  5KA4 A;  3QCB A;  2CM7 A;  1NZ7 A;  2F71 A;  1LQF A;  1KAK A;  1PXH A;  2VEW A;  2H4G A;  2Y2F A;  1I9T A;  4IKC A;  3D42 A;  3OLR A;  1C83 A;  1YTS A;  1QXK A;  2H4V A;  3O5X A;  4GWF A;  2QDC A;  4HJQ A;  4MBB A;  1L8K A;  2C46 A;  3A5K A;  2AZR A;  5EHR A;  2NV5 A;  1PTT A;  2Y96 A;  3RZ2 A;  3O3L A;  1FPZ A;  2H03 A;  1U26 A;  3MOZ A;  3ZM2 A;  2RF6 A;  2P4D A;  4R0T A;  4ZI4 A;  2B4P A;  2BGE A;  5KA0 A;  3AWG A;  4GFU A;  2HXP A;  1OEM X;  4Z6B A;  1GWZ A;  4RH9 A;  2QBS A;  4YR8 B;  1XXV A;  2F6Y A;  4ZN5 A;  1XBO A;  1T4J A;  2YDU A;  2CNI A;  1ZCK A;  1AAX A;  2I4H A;  4KYQ A;  4JMJ A;  1OHE A;  2Q05 A;  1X24 A;  1C85 A;  2F6Z A;  1NWL A;  1PTV A;  3MOW A;  3V0G A;  2F6F A;  2A3K A;  3QCH A; 
#chains in the Genus database with same CATH topology
 2UUO A;  4KYR A;  5IBS A;  3D1O A;  4NX8 A;  3N0A A;  3EB1 A;  2HVL A;  3ZL8 A;  1GQQ A;  4BPC A;  1P31 A;  1EEH A;  2PQ5 A;  1E0D A;  4QDI A;  1Q6M A;  3I36 A;  5BX1 A;  2F00 A;  1Q6P A;  4RKK A;  4DGP A;  5EHP A;  3BLU A;  3QCC A;  1PYN A;  1KAV A;  1UAG A;  2VEY A;  2ZN7 A;  4J51 A;  1ECV A;  1O5Z A;  2GP0 A;  2H04 A;  1P15 A;  1JBV A;  2P6X A;  3QCJ A;  1VHR A;  4ICZ A;  2WJP A;  4WTY A;  2VEX A;  1YGU A;  3S4E A;  2CM8 A;  1I57 A;  5K23 A;  2IMG A;  1NWE A;  2HNP A;  5KA2 A;  1XRI A;  3QCM A;  4WU3 A;  4GRY A;  4RHG A;  4BJO A;  2F70 A;  1G1F A;  1PA9 A;  3EAX A;  2B4U A;  4JMK A;  4QF5 A;  2G6Z A;  1YTW A;  3B7O A;  2A8B A;  2M3V A;  2CFV A;  2HCM A;  3D1Q A;  4AZ1 A;  3ZM5 A;  1PTU A;  2B4O A;  1YZ4 A;  2I4G A;  3V0H A;  2X5O A;  4Y2E A;  4OHI A;  1PA1 A;  5KA8 A;  1P3D A;  3RGQ A;  4RI4 A;  2XPC A;  2ESB A;  1GQY A;  2Y1O A;  2CM2 A;  2CMB A;  3AWE A;  3QCG A;  2BZL A;  4HJP A;  2PT0 A;  1EEN A;  2CMA A;  1T49 A;  3S3K A;  1FQ1 A;  2CMC A;  1V3A A;  3PYZ A;  1Q6J A;  2J17 A;  3O4S A;  4QAH A;  1JLN A;  3SME A;  2J16 B;  4ERC A;  3CWE A;  4PVG A;  3V0F A;  2GJT A;  4WU2 A;  5KAD A;  3F9A A;  2CNF A;  4BUC A;  2WGP A;  5GTJ A;  2H4K A;  3GXH A;  1C88 A;  3NRS A;  3BM8 A;  3EZZ A;  1G1H A;  2VEV A;  2B3O A;  2Y67 A;  3QCL A;  3I80 A;  4GE6 A;  2CNH A;  1G4U S;  4HRF A;  5K9W A;  3ZMP A;  4QBW A;  1W7K A;  2PA5 A;  2R0B A;  3MMJ A;  5BZX A;  2Q47 A;  3QKQ A;  4D3Q A;  2C7S A;  2HC2 A;  2CJZ A;  3D9C A;  1M3G A;  3QCI A;  1OEU A;  1ZCL A;  2QCJ A;  1U24 A;  2WTZ A;  2NLK A;  5K9V A;  2NT7 A;  2I6P A;  2AM1 A;  4NWG A;  2GC5 A;  2I42 A;  2I5X A;  2QBP A;  3F9B A;  2VTE A;  2OC3 A;  1A5Y A;  1J4X A;  2FJN A;  3OMH A;  5K22 A;  3S3H A;  1PH0 A;  4GS0 A;  2BV5 A;  2F6T A;  1G1G A;  2PBN A;  4PYH A;  2GWO A;  2QCT A;  4RI5 A;  3NME A;  4NYH A;  4R30 A;  2B49 A;  2OOQ A;  2J16 A;  4OHE A;  3EU0 A;  4KI9 A;  2QBR A;  3QKP A;  1G7F A;  3F41 A;  4YAA A;  4Y14 A;  1OHC A;  3M4U A;  1W78 A;  1NL9 A;  4OHL A;  1SUG A;  3CM3 A;  4QBE A;  2F6V A;  1XM2 A;  5M43 A;  2B07 A;  4ZRT A;  1U25 A;  5KA3 A;  4DGX A;  4GE5 A;  2PI7 A;  4GFV A;  2JFG A;  1GFY A;  2VOR A;  1QZ0 A;  2NT2 A;  2FJM A;  2Y68 A;  4S0G A;  1FGS A;  1XXP A;  5KA7 A;  1JF7 A;  2F46 A;  3QCE A;  4B04 A;  5IBM A;  1YWF A;  3QCZ A;  5K25 A;  1NNY A;  1WAX A;  2OUD A;  1C86 A;  3BLT A;  4GRZ A;  3V0E A;  1OEV A;  2HNQ A;  3UAG A;  2JFH A;  1OET A;  1NO6 A;  3V0J A;  3EMU A;  1WCH A;  1L8G A;  2I6O A;  2QDP A;  3V0I A;  1C84 A;  5BUG A;  4OHH A;  2JFF A;  1YPT A;  1R6H A;  5AWX A;  2I3R A;  2Y66 A;  2FH7 A;  2I6J A;  1RXD A;  1D5R A;  2NTA A;  4CVK A;  3ZM1 A;  3SR9 A;  1OEO X;  3QCK A;  1PTY A;  1YGR A;  1ZC0 A;  3QCN A;  3ZM6 A;  1BZC A;  1EEO A;  4H34 A;  5J8R A;  3F81 A;  3LJ8 A;  4QUM A;  1J6U A;  2I6I A;  2ZMM A;  3BRH A;  2CM3 A;  1G4W R;  2BIJ A;  5A5F A;  3O4T A;  3ZV2 A;  2F6W A;  5HDE A;  5MMZ B;  1JBW A;  4CVM A;  1Q6T A;  5KAC A;  2CNE A;  5K24 A;  3ZMQ A;  5KAB A;  2I4E A;  2MBC A;  3ZM0 A;  1FPR A;  3V0D A;  3O4U A;  1YN9 A;  2QBQ A;  3S3E A;  1YFO A;  1OHD A;  1Q6S A;  3MVN A;  3LK7 A;  2AHS A;  1LYV A;  2OZ5 A;  5I6V A;  2AM2 A;  2HY3 A;  2CNG A;  2XJA A;  1C87 A;  2I75 A;  2E0T A;  1ONZ A;  1LAR A;  4C12 A;  2HB1 A;  1OES A;  2I6M A;  4GE2 A;  5KAA A;  1BZH A;  1ZZW A;  2I1Y A;  5LXQ B;  1BZJ A;  1ONY A;  1Q6N A;  2DXP A;  2I3U A;  2GC6 A;  3I7Z A;  2H02 A;  3F99 A;  3QCF A;  5BZZ A;  3AWF A;  3D1H A;  2UUP A;  2QEP A;  3D44 A;  2B4S A;  3S4O A;  3RO1 A;  2VEU A;  3A5J A;  4NND A;  4NWF A;  2SHP A;  1G7G A;  4RH5 A;  2JJD A;  3HN7 A;  4JNB A;  2QDM A;  4C13 A;  3PS5 A;  4I8N A;  1MKP A;  1YTN A;  3QCD A;  3GXG A;  3ZM3 A;  1T48 A;  2G59 A;  1RPM A;  4UAG A;  4H1O A;  3S3F A;  1I9S A;  2PSZ A;  2NZ6 A;  1Q1M A;  4TVV A;  3RGO A;  3H2X A;  5A5E A;  5KA1 A;  4WOH A;  4OHD A;  4D3R A;  3U96 A;  2BGD A;  4QUN A;  2HC1 A;  3QCH A;  4D3P A;  4R0S A;  4BUB A;  5KA9 A;  1GG4 A;  4JBC A;  4RDD A;  4QAP A;  5KA4 A;  3QCB A;  2CM7 A;  1NZ7 A;  2F71 A;  1LQF A;  1KAK A;  1PXH A;  2VEW A;  4HV4 A;  2H4G A;  2Y2F A;  2GCA A;  1I9T A;  4IKC A;  3D42 A;  3OLR A;  1C83 A;  1YTS A;  4CVL A;  1QXK A;  2H4V A;  3O5X A;  4GWF A;  2QDC A;  4HJQ A;  4MBB A;  1L8K A;  2C46 A;  3A5K A;  2AZR A;  5EHR A;  2NV5 A;  1PTT A;  2Y96 A;  3RZ2 A;  3O3L A;  1FPZ A;  2H03 A;  1U26 A;  3MOZ A;  3ZM2 A;  2RF6 A;  2P4D A;  4R0T A;  4ZI4 A;  2B4P A;  2BGE A;  5KA0 A;  3AWG A;  4GFU A;  2HXP A;  1OEM X;  4Z6B A;  1GWZ A;  4RH9 A;  4ZIY A;  2QBS A;  2VTD A;  4YR8 B;  1XXV A;  2F6Y A;  2UAG A;  1XBO A;  1T4J A;  4ZN5 A;  2YDU A;  2CNI A;  1ZCK A;  1AAX A;  2I4H A;  2VOS A;  4KYQ A;  4JMJ A;  1OHE A;  2GCB A;  2Q05 A;  1X24 A;  1C85 A;  2F6Z A;  1NWL A;  1PTV A;  3MOW A;  1E8C A;  3N2A A;  3V0G A;  2F6F A;  2A3K A;  1WRM A; 
#chains in the Genus database with same CATH homology
 4KYR A;  5IBS A;  3D1O A;  4NX8 A;  3N0A A;  3EB1 A;  2HVL A;  4BPC A;  2PQ5 A;  1Q6M A;  3I36 A;  5BX1 A;  1Q6P A;  4RKK A;  4DGP A;  5EHP A;  3BLU A;  3QCC A;  1PYN A;  1KAV A;  2VEY A;  2ZN7 A;  4J51 A;  1ECV A;  2GP0 A;  2H04 A;  1P15 A;  2P6X A;  3QCJ A;  1VHR A;  4ICZ A;  4WTY A;  2VEX A;  1YGU A;  3S4E A;  2CM8 A;  1I57 A;  5K23 A;  2IMG A;  1NWE A;  2HNP A;  5KA2 A;  1XRI A;  3QCM A;  4WU3 A;  4GRY A;  4RHG A;  4BJO A;  2F70 A;  1G1F A;  1PA9 A;  3EAX A;  2B4U A;  4JMK A;  1WRM A;  2G6Z A;  1YTW A;  3B7O A;  2A8B A;  2M3V A;  2CFV A;  2HCM A;  3D1Q A;  4AZ1 A;  1PTU A;  2B4O A;  1YZ4 A;  2I4G A;  3V0H A;  4Y2E A;  4OHI A;  1PA1 A;  5KA8 A;  3RGQ A;  4RI4 A;  2ESB A;  2CM2 A;  2CMB A;  3AWE A;  3QCG A;  2BZL A;  4HJP A;  2PT0 A;  1EEN A;  2CMA A;  1T49 A;  3S3K A;  1FQ1 A;  2CMC A;  1V3A A;  1Q6J A;  2J17 A;  3O4S A;  4QAH A;  1JLN A;  3SME A;  2J16 B;  4ERC A;  3CWE A;  4PVG A;  3V0F A;  2GJT A;  4WU2 A;  5KAD A;  3F9A A;  2CNF A;  2WGP A;  5GTJ A;  2H4K A;  3GXH A;  1C88 A;  3BM8 A;  3EZZ A;  1G1H A;  2VEV A;  2B3O A;  3QCL A;  3I80 A;  4GE6 A;  2CNH A;  1G4U S;  4HRF A;  5K9W A;  3ZMP A;  4QBW A;  5BZX A;  2PA5 A;  2R0B A;  3MMJ A;  2Q47 A;  3QKQ A;  4D3Q A;  2C7S A;  2HC2 A;  2CJZ A;  3D9C A;  1M3G A;  3QCI A;  1OEU A;  1ZCL A;  2QCJ A;  1U24 A;  2NLK A;  5K9V A;  2NT7 A;  2I6P A;  4NWG A;  2I42 A;  2I5X A;  2QBP A;  3F9B A;  3S3H A;  2OC3 A;  1A5Y A;  1J4X A;  2FJN A;  3OMH A;  5K22 A;  1PH0 A;  4GS0 A;  2BV5 A;  2F6T A;  1G1G A;  2PBN A;  4PYH A;  2GWO A;  2QCT A;  4RI5 A;  3NME A;  4NYH A;  4R30 A;  2B49 A;  2OOQ A;  2J16 A;  4OHE A;  3EU0 A;  4KI9 A;  2QBR A;  3QKP A;  1G7F A;  3F41 A;  4YAA A;  4Y14 A;  1OHC A;  3M4U A;  1NL9 A;  4OHL A;  1SUG A;  3CM3 A;  4QBE A;  2F6V A;  1XM2 A;  5M43 A;  2B07 A;  4ZRT A;  1U25 A;  5KA3 A;  4DGX A;  4GE5 A;  2PI7 A;  4GFV A;  1GFY A;  1QZ0 A;  2NT2 A;  2FJM A;  4S0G A;  1XXP A;  5KA7 A;  1JF7 A;  2F46 A;  3QCE A;  4B04 A;  5IBM A;  1YWF A;  5K25 A;  1NNY A;  1WAX A;  2OUD A;  1C86 A;  3BLT A;  4GRZ A;  3V0E A;  1OEV A;  2HNQ A;  1OET A;  1NO6 A;  3V0J A;  3EMU A;  1WCH A;  1L8G A;  2I6O A;  2QDP A;  3V0I A;  1C84 A;  5BUG A;  4OHH A;  1YPT A;  1R6H A;  5AWX A;  2I3R A;  2FH7 A;  2I6J A;  1RXD A;  1D5R A;  2NTA A;  3ZM1 A;  3SR9 A;  1OEO X;  3QCK A;  1PTY A;  1YGR A;  1ZC0 A;  3QCN A;  1BZC A;  1EEO A;  4H34 A;  5J8R A;  3F81 A;  3LJ8 A;  4QUM A;  2I6I A;  2ZMM A;  3BRH A;  2CM3 A;  1G4W R;  2BIJ A;  3O4T A;  3ZV2 A;  2F6W A;  5HDE A;  5MMZ B;  1Q6T A;  5KAC A;  2CNE A;  5K24 A;  3ZMQ A;  5KAB A;  2I4E A;  2MBC A;  3ZM0 A;  1FPR A;  3V0D A;  3O4U A;  1YN9 A;  2QBQ A;  3S3E A;  1YFO A;  1OHD A;  1Q6S A;  2AHS A;  1LYV A;  2OZ5 A;  5I6V A;  2HY3 A;  2CNG A;  1C87 A;  2I75 A;  2E0T A;  1ONZ A;  1LAR A;  2HB1 A;  1OES A;  2I6M A;  4GE2 A;  5KAA A;  1BZH A;  1ZZW A;  2I1Y A;  5LXQ B;  1BZJ A;  1ONY A;  1Q6N A;  2DXP A;  2I3U A;  3I7Z A;  2H02 A;  3F99 A;  3QCF A;  5BZZ A;  3AWF A;  3D1H A;  2QEP A;  3D44 A;  2B4S A;  3S4O A;  3RO1 A;  2VEU A;  3A5J A;  4NND A;  4NWF A;  2SHP A;  1G7G A;  4RH5 A;  2JJD A;  4JNB A;  2QDM A;  3PS5 A;  4I8N A;  1MKP A;  1YTN A;  3QCD A;  3GXG A;  3ZM3 A;  1T48 A;  2G59 A;  1RPM A;  4H1O A;  3S3F A;  1I9S A;  2PSZ A;  2NZ6 A;  1Q1M A;  4TVV A;  3RGO A;  3H2X A;  5KA1 A;  4WOH A;  4OHD A;  4D3R A;  3U96 A;  2BGD A;  4QUN A;  2HC1 A;  4D3P A;  4R0S A;  5KA9 A;  4JBC A;  4RDD A;  4QAP A;  5KA4 A;  3QCB A;  2CM7 A;  1NZ7 A;  2F71 A;  1LQF A;  1KAK A;  1PXH A;  2VEW A;  2H4G A;  2Y2F A;  1I9T A;  4IKC A;  3D42 A;  3OLR A;  1C83 A;  1YTS A;  1QXK A;  2H4V A;  3O5X A;  4GWF A;  2QDC A;  4HJQ A;  4MBB A;  1L8K A;  2C46 A;  3A5K A;  2AZR A;  5EHR A;  2NV5 A;  1PTT A;  2Y96 A;  3RZ2 A;  3O3L A;  1FPZ A;  2H03 A;  1U26 A;  3MOZ A;  3ZM2 A;  2RF6 A;  2P4D A;  4R0T A;  4ZI4 A;  2B4P A;  2BGE A;  5KA0 A;  3AWG A;  4GFU A;  2HXP A;  1OEM X;  4Z6B A;  1GWZ A;  4RH9 A;  2QBS A;  4YR8 B;  1XXV A;  2F6Y A;  4ZN5 A;  1XBO A;  1T4J A;  2YDU A;  2CNI A;  1ZCK A;  1AAX A;  2I4H A;  4KYQ A;  4JMJ A;  1OHE A;  2Q05 A;  1X24 A;  1C85 A;  2F6Z A;  1NWL A;  1PTV A;  3MOW A;  3V0G A;  2F6F A;  2A3K A;  3QCH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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