1KR3A

Crystal structure of the metallo beta-lactamase from bacteroides fragilis (cfia) in complex with the tricyclic inhibitor sb-236050.
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
227
structure length
227
Chain Sequence
SVKISDDISITQLSDKVYTYVSLAEIEGWGMVPSNGMIVINNHQAALLDTPINDAQTEMLVNWVTDSLHAKVTTFIPNHWHGDCIGGLGYLQRKGVQSYANQMTIDLAKEKGLPVPEHGFTDSLTVSLDGMPLQCYYLGGGHATDNIVVWLPTENILFGGCMLKDNQATSIGNISDADVTAWPKTLDKVKAKFPSARYVVPGHGDYGGTELIEHTKQIVNQYIESTS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords beta-Lactamase, type II
publication title Identification of a series of tricyclic natural products as potent broad-spectrum inhibitors of metallo-beta-lactamases
pubmed doi rcsb
source organism Bacteroides fragilis
molecule tags Hydrolase
total genus 67
structure length 227
sequence length 227
chains with identical sequence B
ec nomenclature ec 3.5.2.6: Beta-lactamase.
pdb deposition date 2002-01-08
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 1kr3A00
4B87A 3DHCA 2M5DA 4P62A 5B3RA 3I13A 4BP0A 3IE1A 1A7TA 4TYFA 2WYMA 3PG4A 4UAMA 4DIKA 2UYXA 2OHIA 4YSKA 2GMNA 3IOFA 4D1VA 4LE6A 2AZ4A 4RM5A 4KEQA 5FQCA 5EV8A 5K0WA 3T3OA 3SW3A 3IE0A 4NQ4A 5EV6A 3TP9A 2M5CA 2YZ3A 2OHJA 5LSCA 2P18A 5AXRA 1QH5A 2GFKA 2FU8A 2YCBA 4GCWA 3SD9A 5IQKA 3SFPA 3SPUA 5LCFA 4XWTA 4ZO2A 4JO0A 1DDKA 3ESHA 2DOOA 3ZR9A 2BG2A 5ACQA 1VGNA 2BG8A 3H3EA 1A8TA 3RKKA 1L9YA 4AWYB 4XWWA 1JJTA 3KNRA 2QDTA 1ZNBA 2QEDA 2QINA 3IEMA 4AWZA 2ZWRA 1JT1A 3PY6A 2FK6A 5KILA 5AEBA 2YNUA 4D1TA 5HH6A 5K4KA 3JXPA 1QH3A 2Y8BA 1XTOA 1ZKPA 4Z5ZA 2BMIA 5EHTA 3IEKA 1KO2A 4F6HA 4UWPB 4TZBA 3P2UA 4TZEA 5A0TA 2VW8A 2ZZIA 5ACTA 2YNVB 5ACXA 3AJ3A 4EXYA 4WD6A 4HL2A 5HH5A 3FAIA 3KNSA 3X2ZA 4D1UA 3FCZA 2WRSA 3LVZA 2GFJA 3ZNBA 3X2YA 3X2XA 4PVTA 3IOGA 1BC2A 3PY5A 3X30A 5LMCA 3I15A 2NYPA 2P1EA 3AF6A 2YNTA 5AHRA 5ACPA 1XM8A 4D1WA 2FHXB 5B1UA 1JJEA 4D02A 5A0VA 5ACWA 3QH8A 1M2XA 3ZWFA 1X8HA 4TZFA 4Z6XA 4Z60A 3I0VA 3I11A 4AX0B 4HL1A 3ZQ4A 3SRXA 2YNWA 4C1HA 2BIBA 2BC2A 4C1DA 1KO3A 3DHAA 4EY2A 4BZ3A 4C09A 5AHOA 5LLDA 5ACRA 5LCHA 2NZFA 2P4ZA 2FU9A 4EFZA 2BR6A 4YSLA 5EVBA 5HH4A 2Q0JA 2BTNA 3BK1A 4GYQA 1WUOA 1X8GA 3Q6VA 1YCHA 3DH8A 2NZEA 2CBNA 3ADRA 2I7VA 1DXKA 3VQZA 4TYTA 2Y87A 3IELA 4RBSA 2Q0IA 4AD9A 4DILA 3I14A 1MQOA 2GCUA 3IE2A 4FSBA 2AIOA 2BG8B 5LM6A 2H6AA 3T3NA 4UWOB 2BFZA 4PVOA 4EYFA 4C1FA 2P97A 2R2DA 3RPCA 3DHBA 4ZEJA 1YCFA 1DD6A 4H0DA 5KIKA 2BFKA 4ZNBA 4F6ZA 5EVKA 4TZ9A 1VMEA 3F9OA 4RAMA 3T9MA 4C1EA 5K4MA 4RL2A 4UBQA 5HIQA 3R2UA 4J5HA 2Q9UA 4C1CA 4NQ2A 5B15A 3IDZA 4UWRB 2Q42A 4NQ5A 3BC2A 5LCAA 2FM6A 2WHGA 4GYUA 1WW1A 1Y44A 5HIOA 4XUKA 2BG7A 2FU7A 4UWSB 1SMLA 2NXAA 3A4YA 1E5DA 3KL7A 5EH9A 1VJNA 1WUPA 1HLKA 4Z7RA 4EXSA 4Z5YA 4HKYA 2YNTB 2BGAA 3MD7A 2WYLA 5A87A 2BG6A 3G1PA 4RL0A 4YSBA 5LS3A 2HB9A 2I7TA 4EYBA 4EYLA 2WYMC 2I7XA 5AXOA 4UA4A 1X8IA 1BVTA 5HISA 1YCGA 4KEPA 4O98A 1WRAA 4U4LA 5ACVA 4C1GA 5EVDA 2OHHA 3WXCA 3BV6A 1KR3A 4RAWA 2DKFA 2YNVA 4V0HA 2QDSA 5A5ZA 5LE1A 5FQAA 4FR7A 4ZO3A 3S0ZA 1ZTCA 2XR1A 2BFLA 4AX1B 2XF4A 1BMCA 2FHXA 5DPXA 3VPEA 5K4NA 2A7MA 2FU6A 2ZNBA 2Y8AA 3AF5A 2ZO4A 2GKLA 2E7YA 3BK2A 4Z67A 5ACSA 2QJSA 5EWAA 4NQ6A 5HIPA 5AYAA 5FQBA 4FEKA 1K07A 4CHLA 3RKJA 3SBLA 2BFZB 3L6NA 4J5FA 1P9EA 5EW0A 5ACUA
chains in the Genus database with same CATH superfamily
4B87A 3DHCA 2M5DA 4P62A 5B3RA 3I13A 4BP0A 3IE1A 1A7TA 4TYFA 2WYMA 3PG4A 4UAMA 4DIKA 2UYXA 2OHIA 4YSKA 2GMNA 3IOFA 4D1VA 2YHEA 4LE6A 2AZ4A 4RM5A 4KEQA 5FQCA 5EV8A 5K0WA 3T3OA 3SW3A 3IE0A 4NQ4A 5EV6A 3TP9A 2M5CA 2YZ3A 2OHJA 5LSCA 2P18A 5AXRA 1QH5A 2GFKA 2FU8A 2YCBA 4GCWA 3SD9A 5IQKA 3SFPA 3SPUA 5LCFA 4XWTA 4ZO2A 4JO0A 1DDKA 3ESHA 2DOOA 3ZR9A 2BG2A 5ACQA 1VGNA 2BG8A 3H3EA 1A8TA 3RKKA 1L9YA 4AWYB 4XWWA 1JJTA 3KNRA 2QDTA 1ZNBA 2QEDA 2QINA 3IEMA 4AWZA 2ZWRA 1JT1A 3PY6A 2FK6A 5KILA 5AEBA 2YNUA 4D1TA 5HH6A 5K4KA 3JXPA 1QH3A 4PDXA 2Y8BA 1XTOA 1ZKPA 4Z5ZA 2BMIA 5EHTA 3IEKA 1KO2A 4F6HA 4UWPB 4TZBA 3P2UA 4TZEA 5A0TA 2VW8A 2ZZIA 5ACTA 2YNVB 5ACXA 3AJ3A 4EXYA 4WD6A 4HL2A 5HH5A 3FAIA 3KNSA 3X2ZA 4D1UA 3FCZA 2WRSA 3LVZA 2GFJA 3ZNBA 3X2YA 3X2XA 4PVTA 3IOGA 1BC2A 3PY5A 3X30A 5LMCA 3I15A 2NYPA 2P1EA 3AF6A 2YNTA 5AHRA 5ACPA 1XM8A 4D1WA 2FHXB 5B1UA 1JJEA 4D02A 5A0VA 5ACWA 3QH8A 1M2XA 3ZWFA 1X8HA 4TZFA 4Z6XA 4Z60A 3I0VA 3I11A 4AX0B 4HL1A 3ZQ4A 3SRXA 2YNWA 4C1HA 2BIBA 2BC2A 4C1DA 5A23A 1KO3A 3DHAA 4EY2A 4BZ3A 4C09A 5AHOA 5LLDA 5ACRA 5LCHA 2NZFA 2P4ZA 2FU9A 4EFZA 2BR6A 4YSLA 5EVBA 5HH4A 2Q0JA 2BTNA 3BK1A 4GYQA 1WUOA 1X8GA 3Q6VA 1YCHA 3DH8A 2NZEA 2CBNA 3ADRA 2I7VA 1DXKA 3VQZA 4TYTA 2Y87A 3IELA 4RBSA 2Q0IA 4AD9A 4DILA 3I14A 1MQOA 2GCUA 3IE2A 4FSBA 5AIJA 2AIOA 2BG8B 5LM6A 2H6AA 3T3NA 2CFUA 4UWOB 2BFZA 2CG3A 4PVOA 4EYFA 4C1FA 2P97A 2R2DA 3RPCA 3DHBA 4ZEJA 1YCFA 1DD6A 4H0DA 5KIKA 2BFKA 4ZNBA 4F6ZA 5EVKA 4TZ9A 1VMEA 3F9OA 4RAMA 3T9MA 4C1EA 5K4MA 4RL2A 4UBQA 5HIQA 3R2UA 4J5HA 2Q9UA 4C1CA 4NQ2A 5B15A 3IDZA 4UWRB 2CG2A 4AV7A 2Q42A 4NQ5A 3BC2A 5LCAA 2FM6A 2WHGA 4GYUA 1WW1A 1Y44A 5AJLA 5HIOA 4XUKA 2BG7A 2FU7A 4AXHA 4UWSB 1SMLA 2NXAA 3A4YA 1E5DA 3KL7A 5EH9A 1VJNA 1WUPA 1HLKA 4Z7RA 4EXSA 4Z5YA 4HKYA 2YNTB 2BGAA 3MD7A 2CFZA 2WYLA 5A87A 2BG6A 3G1PA 4RL0A 4YSBA 5LS3A 2HB9A 2I7TA 4EYBA 4EYLA 2WYMC 2I7XA 5AXOA 4UA4A 1X8IA 1BVTA 5HISA 1YCGA 4KEPA 4O98A 1WRAA 4U4LA 5ACVA 4C1GA 5EVDA 2OHHA 3WXCA 3BV6A 1KR3A 4RAWA 2DKFA 2YNVA 4V0HA 2QDSA 5A5ZA 5LE1A 5FQAA 4FR7A 4ZO3A 3S0ZA 1ZTCA 2XR1A 2BFLA 4AX1B 2XF4A 1BMCA 2FHXA 5DPXA 3VPEA 5K4NA 2A7MA 2FU6A 2ZNBA 2Y8AA 3AF5A 2ZO4A 2GKLA 2E7YA 3BK2A 4Z67A 5ACSA 2QJSA 5EWAA 4NQ6A 5HIPA 4NURA 5AYAA 5FQBA 4FEKA 1K07A 4CHLA 3RKJA 3SBLA 2BFZB 3L6NA 4J5FA 1P9EA 5EW0A 5ACUA
chains in the Genus database with same CATH topology
4B87A 3DHCA 2M5DA 4P62A 5B3RA 3I13A 4BP0A 3IE1A 1A7TA 4TYFA 2WYMA 3PG4A 4UAMA 4DIKA 2UYXA 2OHIA 4YSKA 2GMNA 3IOFA 4D1VA 4LE6A 2AZ4A 4RM5A 4KEQA 5FQCA 5EV8A 5K0WA 3T3OA 3SW3A 3IE0A 4NQ4A 5EV6A 3TP9A 2M5CA 2YZ3A 2OHJA 5LSCA 2P18A 5AXRA 1QH5A 2GFKA 2FU8A 2YCBA 4GCWA 3SD9A 5IQKA 3SFPA 3SPUA 5LCFA 4XWTA 4ZO2A 4JO0A 1DDKA 3ESHA 2DOOA 3ZR9A 2BG2A 5ACQA 1VGNA 2BG8A 3H3EA 1A8TA 3RKKA 1L9YA 4AWYB 4XWWA 1JJTA 3KNRA 2QDTA 1ZNBA 2QEDA 2QINA 3IEMA 4AWZA 2ZWRA 1JT1A 3PY6A 2FK6A 5KILA 5AEBA 2YNUA 4D1TA 5HH6A 5K4KA 3JXPA 1QH3A 2Y8BA 1XTOA 1ZKPA 4Z5ZA 2BMIA 5EHTA 3IEKA 1KO2A 4F6HA 4UWPB 4TZBA 3P2UA 4TZEA 5A0TA 2VW8A 2ZZIA 5ACTA 2YNVB 5ACXA 3AJ3A 4EXYA 4WD6A 4HL2A 5HH5A 3FAIA 3KNSA 3X2ZA 4D1UA 3FCZA 2WRSA 3LVZA 2GFJA 3ZNBA 3X2YA 3X2XA 4PVTA 3IOGA 1BC2A 3PY5A 3X30A 5LMCA 3I15A 2NYPA 2P1EA 3AF6A 2YNTA 5AHRA 5ACPA 1XM8A 4D1WA 2FHXB 5B1UA 1JJEA 4D02A 5A0VA 5ACWA 3QH8A 1M2XA 3ZWFA 1X8HA 4TZFA 4Z6XA 4Z60A 3I0VA 3I11A 4AX0B 4HL1A 3ZQ4A 3SRXA 2YNWA 4C1HA 2BIBA 2BC2A 4C1DA 1KO3A 3DHAA 4EY2A 4BZ3A 4C09A 5AHOA 5LLDA 5ACRA 5LCHA 2NZFA 2P4ZA 2FU9A 4EFZA 2BR6A 4YSLA 5EVBA 5HH4A 2Q0JA 2BTNA 3BK1A 4GYQA 1WUOA 1X8GA 3Q6VA 1YCHA 3DH8A 2NZEA 2CBNA 3ADRA 2I7VA 1DXKA 3VQZA 4TYTA 2Y87A 3IELA 4RBSA 2Q0IA 4AD9A 4DILA 3I14A 1MQOA 2GCUA 3IE2A 4FSBA 2AIOA 2BG8B 5LM6A 2H6AA 3T3NA 4UWOB 2BFZA 4PVOA 4EYFA 4C1FA 2P97A 2R2DA 3RPCA 3DHBA 4ZEJA 1YCFA 1DD6A 4H0DA 5KIKA 2BFKA 4ZNBA 4F6ZA 5EVKA 4TZ9A 1VMEA 3F9OA 4RAMA 3T9MA 4C1EA 5K4MA 4RL2A 4UBQA 5HIQA 3R2UA 4J5HA 2Q9UA 4C1CA 4NQ2A 5B15A 3IDZA 4UWRB 2Q42A 4NQ5A 3BC2A 5LCAA 2FM6A 2WHGA 4GYUA 1WW1A 1Y44A 5HIOA 4XUKA 2BG7A 2FU7A 4UWSB 1SMLA 2NXAA 3A4YA 1E5DA 3KL7A 5EH9A 1VJNA 1WUPA 1HLKA 4Z7RA 4EXSA 4Z5YA 4HKYA 2YNTB 2BGAA 3MD7A 2WYLA 5A87A 2BG6A 3G1PA 4RL0A 4YSBA 5LS3A 2HB9A 2I7TA 4EYBA 4EYLA 2WYMC 2I7XA 5AXOA 4UA4A 1X8IA 1BVTA 5HISA 1YCGA 4KEPA 4O98A 1WRAA 4U4LA 5ACVA 4C1GA 5EVDA 2OHHA 3WXCA 3BV6A 1KR3A 4RAWA 2DKFA 2YNVA 4V0HA 2QDSA 5A5ZA 5LE1A 5FQAA 4FR7A 4ZO3A 3S0ZA 1ZTCA 2XR1A 2BFLA 4AX1B 2XF4A 1BMCA 2FHXA 5DPXA 3VPEA 5K4NA 2A7MA 2FU6A 2ZNBA 2Y8AA 3AF5A 2ZO4A 2GKLA 2E7YA 3BK2A 4Z67A 5ACSA 2QJSA 5EWAA 4NQ6A 5HIPA 5AYAA 5FQBA 4FEKA 1K07A 4CHLA 3RKJA 3SBLA 2BFZB 3L6NA 4J5FA 1P9EA 5EW0A 5ACUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4B87 A;  3DHC A;  2M5D A;  4P62 A;  5B3R A;  3I13 A;  4BP0 A;  3IE1 A;  1A7T A;  4TYF A;  2WYM A;  3PG4 A;  4UAM A;  4DIK A;  2UYX A;  2OHI A;  4YSK A;  2GMN A;  3IOF A;  4D1V A;  4LE6 A;  2AZ4 A;  4RM5 A;  4KEQ A;  5FQC A;  5EV8 A;  5K0W A;  3T3O A;  3SW3 A;  3IE0 A;  4NQ4 A;  5EV6 A;  3TP9 A;  2M5C A;  2YZ3 A;  2OHJ A;  5LSC A;  2P18 A;  5AXR A;  1QH5 A;  2GFK A;  2FU8 A;  2YCB A;  4GCW A;  3SD9 A;  5IQK A;  3SFP A;  3SPU A;  5LCF A;  4XWT A;  4ZO2 A;  4JO0 A;  1DDK A;  3ESH A;  2DOO A;  3ZR9 A;  2BG2 A;  5ACQ A;  1VGN A;  2BG8 A;  3H3E A;  1A8T A;  3RKK A;  1L9Y A;  4AWY B;  4XWW A;  1JJT A;  3KNR A;  2QDT A;  1ZNB A;  2QED A;  2QIN A;  3IEM A;  4AWZ A;  2ZWR A;  1JT1 A;  3PY6 A;  2FK6 A;  5KIL A;  5AEB A;  2YNU A;  4D1T A;  5HH6 A;  5K4K A;  3JXP A;  1QH3 A;  2Y8B A;  1XTO A;  1ZKP A;  4Z5Z A;  2BMI A;  5EHT A;  3IEK A;  1KO2 A;  4F6H A;  4UWP B;  4TZB A;  3P2U A;  4TZE A;  5A0T A;  2VW8 A;  2ZZI A;  5ACT A;  2YNV B;  5ACX A;  3AJ3 A;  4EXY A;  4WD6 A;  4HL2 A;  5HH5 A;  3FAI A;  3KNS A;  3X2Z A;  4D1U A;  3FCZ A;  2WRS A;  3LVZ A;  2GFJ A;  3ZNB A;  3X2Y A;  3X2X A;  4PVT A;  3IOG A;  1BC2 A;  3PY5 A;  3X30 A;  5LMC A;  3I15 A;  2NYP A;  2P1E A;  3AF6 A;  2YNT A;  5AHR A;  5ACP A;  1XM8 A;  4D1W A;  2FHX B;  5B1U A;  1JJE A;  4D02 A;  5A0V A;  5ACW A;  3QH8 A;  1M2X A;  3ZWF A;  1X8H A;  4TZF A;  4Z6X A;  4Z60 A;  3I0V A;  3I11 A;  4AX0 B;  4HL1 A;  3ZQ4 A;  3SRX A;  2YNW A;  4C1H A;  2BIB A;  2BC2 A;  4C1D A;  1KO3 A;  3DHA A;  4EY2 A;  4BZ3 A;  4C09 A;  5AHO A;  5LLD A;  5ACR A;  5LCH A;  2NZF A;  2P4Z A;  2FU9 A;  4EFZ A;  2BR6 A;  4YSL A;  5EVB A;  5HH4 A;  2Q0J A;  2BTN A;  3BK1 A;  4GYQ A;  1WUO A;  1X8G A;  3Q6V A;  1YCH A;  3DH8 A;  2NZE A;  2CBN A;  3ADR A;  2I7V A;  1DXK A;  3VQZ A;  4TYT A;  2Y87 A;  3IEL A;  4RBS A;  2Q0I A;  4AD9 A;  4DIL A;  3I14 A;  1MQO A;  2GCU A;  3IE2 A;  4FSB A;  2AIO A;  2BG8 B;  5LM6 A;  2H6A A;  3T3N A;  4UWO B;  2BFZ A;  4PVO A;  4EYF A;  4C1F A;  2P97 A;  2R2D A;  3RPC A;  3DHB A;  4ZEJ A;  1YCF A;  1DD6 A;  4H0D A;  5KIK A;  2BFK A;  4ZNB A;  4F6Z A;  5EVK A;  4TZ9 A;  1VME A;  3F9O A;  4RAM A;  3T9M A;  4C1E A;  5K4M A;  4RL2 A;  4UBQ A;  5HIQ A;  3R2U A;  4J5H A;  2Q9U A;  4C1C A;  4NQ2 A;  5B15 A;  3IDZ A;  4UWR B;  2Q42 A;  4NQ5 A;  3BC2 A;  5LCA A;  2FM6 A;  2WHG A;  4GYU A;  1WW1 A;  1Y44 A;  5HIO A;  4XUK A;  2BG7 A;  2FU7 A;  4UWS B;  1SML A;  2NXA A;  3A4Y A;  1E5D A;  3KL7 A;  5EH9 A;  1VJN A;  1WUP A;  1HLK A;  4Z7R A;  4EXS A;  4Z5Y A;  4HKY A;  2YNT B;  2BGA A;  3MD7 A;  2WYL A;  5A87 A;  2BG6 A;  3G1P A;  4RL0 A;  4YSB A;  5LS3 A;  2HB9 A;  2I7T A;  4EYB A;  4EYL A;  2WYM C;  2I7X A;  5AXO A;  4UA4 A;  1X8I A;  1BVT A;  5HIS A;  1YCG A;  4KEP A;  4O98 A;  1WRA A;  4U4L A;  5ACV A;  4C1G A;  5EVD A;  2OHH A;  3WXC A;  3BV6 A;  1KR3 A;  4RAW A;  2DKF A;  2YNV A;  4V0H A;  2QDS A;  5A5Z A;  5LE1 A;  5FQA A;  4FR7 A;  4ZO3 A;  3S0Z A;  1ZTC A;  2XR1 A;  2BFL A;  4AX1 B;  2XF4 A;  1BMC A;  2FHX A;  5DPX A;  3VPE A;  5K4N A;  2A7M A;  2FU6 A;  2ZNB A;  2Y8A A;  3AF5 A;  2ZO4 A;  2GKL A;  2E7Y A;  3BK2 A;  4Z67 A;  5ACS A;  2QJS A;  5EWA A;  4NQ6 A;  5HIP A;  5AYA A;  5FQB A;  4FEK A;  1K07 A;  4CHL A;  3RKJ A;  3SBL A;  2BFZ B;  3L6N A;  4J5F A;  1P9E A;  5EW0 A;  5ACU A; 
#chains in the Genus database with same CATH topology
 4B87 A;  3DHC A;  2M5D A;  4P62 A;  5B3R A;  3I13 A;  4BP0 A;  3IE1 A;  1A7T A;  4TYF A;  2WYM A;  3PG4 A;  4UAM A;  4DIK A;  2UYX A;  2OHI A;  4YSK A;  2GMN A;  3IOF A;  4D1V A;  2YHE A;  4LE6 A;  2AZ4 A;  4RM5 A;  4KEQ A;  5FQC A;  5EV8 A;  5K0W A;  3T3O A;  3SW3 A;  3IE0 A;  4NQ4 A;  5EV6 A;  3TP9 A;  2M5C A;  2YZ3 A;  2OHJ A;  5LSC A;  2P18 A;  5AXR A;  1QH5 A;  2GFK A;  2FU8 A;  2YCB A;  4GCW A;  3SD9 A;  5IQK A;  3SFP A;  3SPU A;  5LCF A;  4XWT A;  4ZO2 A;  4JO0 A;  1DDK A;  3ESH A;  2DOO A;  3ZR9 A;  2BG2 A;  5ACQ A;  1VGN A;  2BG8 A;  3H3E A;  1A8T A;  3RKK A;  1L9Y A;  4AWY B;  4XWW A;  1JJT A;  3KNR A;  2QDT A;  1ZNB A;  2QED A;  2QIN A;  3IEM A;  4AWZ A;  2ZWR A;  1JT1 A;  3PY6 A;  2FK6 A;  5KIL A;  5AEB A;  2YNU A;  4D1T A;  5HH6 A;  5K4K A;  3JXP A;  1QH3 A;  4PDX A;  2Y8B A;  1XTO A;  1ZKP A;  4Z5Z A;  2BMI A;  5EHT A;  3IEK A;  1KO2 A;  4F6H A;  4UWP B;  4TZB A;  3P2U A;  4TZE A;  5A0T A;  2VW8 A;  2ZZI A;  5ACT A;  2YNV B;  5ACX A;  3AJ3 A;  4EXY A;  4WD6 A;  4HL2 A;  5HH5 A;  3FAI A;  3KNS A;  3X2Z A;  4D1U A;  3FCZ A;  2WRS A;  3LVZ A;  2GFJ A;  3ZNB A;  3X2Y A;  3X2X A;  4PVT A;  3IOG A;  1BC2 A;  3PY5 A;  3X30 A;  5LMC A;  3I15 A;  2NYP A;  2P1E A;  3AF6 A;  2YNT A;  5AHR A;  5ACP A;  1XM8 A;  4D1W A;  2FHX B;  5B1U A;  1JJE A;  4D02 A;  5A0V A;  5ACW A;  3QH8 A;  1M2X A;  3ZWF A;  1X8H A;  4TZF A;  4Z6X A;  4Z60 A;  3I0V A;  3I11 A;  4AX0 B;  4HL1 A;  3ZQ4 A;  3SRX A;  2YNW A;  4C1H A;  2BIB A;  2BC2 A;  4C1D A;  5A23 A;  1KO3 A;  3DHA A;  4EY2 A;  4BZ3 A;  4C09 A;  5AHO A;  5LLD A;  5ACR A;  5LCH A;  2NZF A;  2P4Z A;  2FU9 A;  4EFZ A;  2BR6 A;  4YSL A;  5EVB A;  5HH4 A;  2Q0J A;  2BTN A;  3BK1 A;  4GYQ A;  1WUO A;  1X8G A;  3Q6V A;  1YCH A;  3DH8 A;  2NZE A;  2CBN A;  3ADR A;  2I7V A;  1DXK A;  3VQZ A;  4TYT A;  2Y87 A;  3IEL A;  4RBS A;  2Q0I A;  4AD9 A;  4DIL A;  3I14 A;  1MQO A;  2GCU A;  3IE2 A;  4FSB A;  5AIJ A;  2AIO A;  2BG8 B;  5LM6 A;  2H6A A;  3T3N A;  2CFU A;  4UWO B;  2BFZ A;  2CG3 A;  4PVO A;  4EYF A;  4C1F A;  2P97 A;  2R2D A;  3RPC A;  3DHB A;  4ZEJ A;  1YCF A;  1DD6 A;  4H0D A;  5KIK A;  2BFK A;  4ZNB A;  4F6Z A;  5EVK A;  4TZ9 A;  1VME A;  3F9O A;  4RAM A;  3T9M A;  4C1E A;  5K4M A;  4RL2 A;  4UBQ A;  5HIQ A;  3R2U A;  4J5H A;  2Q9U A;  4C1C A;  4NQ2 A;  5B15 A;  3IDZ A;  4UWR B;  2CG2 A;  4AV7 A;  2Q42 A;  4NQ5 A;  3BC2 A;  5LCA A;  2FM6 A;  2WHG A;  4GYU A;  1WW1 A;  1Y44 A;  5AJL A;  5HIO A;  4XUK A;  2BG7 A;  2FU7 A;  4AXH A;  4UWS B;  1SML A;  2NXA A;  3A4Y A;  1E5D A;  3KL7 A;  5EH9 A;  1VJN A;  1WUP A;  1HLK A;  4Z7R A;  4EXS A;  4Z5Y A;  4HKY A;  2YNT B;  2BGA A;  3MD7 A;  2CFZ A;  2WYL A;  5A87 A;  2BG6 A;  3G1P A;  4RL0 A;  4YSB A;  5LS3 A;  2HB9 A;  2I7T A;  4EYB A;  4EYL A;  2WYM C;  2I7X A;  5AXO A;  4UA4 A;  1X8I A;  1BVT A;  5HIS A;  1YCG A;  4KEP A;  4O98 A;  1WRA A;  4U4L A;  5ACV A;  4C1G A;  5EVD A;  2OHH A;  3WXC A;  3BV6 A;  1KR3 A;  4RAW A;  2DKF A;  2YNV A;  4V0H A;  2QDS A;  5A5Z A;  5LE1 A;  5FQA A;  4FR7 A;  4ZO3 A;  3S0Z A;  1ZTC A;  2XR1 A;  2BFL A;  4AX1 B;  2XF4 A;  1BMC A;  2FHX A;  5DPX A;  3VPE A;  5K4N A;  2A7M A;  2FU6 A;  2ZNB A;  2Y8A A;  3AF5 A;  2ZO4 A;  2GKL A;  2E7Y A;  3BK2 A;  4Z67 A;  5ACS A;  2QJS A;  5EWA A;  4NQ6 A;  5HIP A;  4NUR A;  5AYA A;  5FQB A;  4FEK A;  1K07 A;  4CHL A;  3RKJ A;  3SBL A;  2BFZ B;  3L6N A;  4J5F A;  1P9E A;  5EW0 A;  5ACU A; 
#chains in the Genus database with same CATH homology
 4B87 A;  3DHC A;  2M5D A;  4P62 A;  5B3R A;  3I13 A;  4BP0 A;  3IE1 A;  1A7T A;  4TYF A;  2WYM A;  3PG4 A;  4UAM A;  4DIK A;  2UYX A;  2OHI A;  4YSK A;  2GMN A;  3IOF A;  4D1V A;  4LE6 A;  2AZ4 A;  4RM5 A;  4KEQ A;  5FQC A;  5EV8 A;  5K0W A;  3T3O A;  3SW3 A;  3IE0 A;  4NQ4 A;  5EV6 A;  3TP9 A;  2M5C A;  2YZ3 A;  2OHJ A;  5LSC A;  2P18 A;  5AXR A;  1QH5 A;  2GFK A;  2FU8 A;  2YCB A;  4GCW A;  3SD9 A;  5IQK A;  3SFP A;  3SPU A;  5LCF A;  4XWT A;  4ZO2 A;  4JO0 A;  1DDK A;  3ESH A;  2DOO A;  3ZR9 A;  2BG2 A;  5ACQ A;  1VGN A;  2BG8 A;  3H3E A;  1A8T A;  3RKK A;  1L9Y A;  4AWY B;  4XWW A;  1JJT A;  3KNR A;  2QDT A;  1ZNB A;  2QED A;  2QIN A;  3IEM A;  4AWZ A;  2ZWR A;  1JT1 A;  3PY6 A;  2FK6 A;  5KIL A;  5AEB A;  2YNU A;  4D1T A;  5HH6 A;  5K4K A;  3JXP A;  1QH3 A;  2Y8B A;  1XTO A;  1ZKP A;  4Z5Z A;  2BMI A;  5EHT A;  3IEK A;  1KO2 A;  4F6H A;  4UWP B;  4TZB A;  3P2U A;  4TZE A;  5A0T A;  2VW8 A;  2ZZI A;  5ACT A;  2YNV B;  5ACX A;  3AJ3 A;  4EXY A;  4WD6 A;  4HL2 A;  5HH5 A;  3FAI A;  3KNS A;  3X2Z A;  4D1U A;  3FCZ A;  2WRS A;  3LVZ A;  2GFJ A;  3ZNB A;  3X2Y A;  3X2X A;  4PVT A;  3IOG A;  1BC2 A;  3PY5 A;  3X30 A;  5LMC A;  3I15 A;  2NYP A;  2P1E A;  3AF6 A;  2YNT A;  5AHR A;  5ACP A;  1XM8 A;  4D1W A;  2FHX B;  5B1U A;  1JJE A;  4D02 A;  5A0V A;  5ACW A;  3QH8 A;  1M2X A;  3ZWF A;  1X8H A;  4TZF A;  4Z6X A;  4Z60 A;  3I0V A;  3I11 A;  4AX0 B;  4HL1 A;  3ZQ4 A;  3SRX A;  2YNW A;  4C1H A;  2BIB A;  2BC2 A;  4C1D A;  1KO3 A;  3DHA A;  4EY2 A;  4BZ3 A;  4C09 A;  5AHO A;  5LLD A;  5ACR A;  5LCH A;  2NZF A;  2P4Z A;  2FU9 A;  4EFZ A;  2BR6 A;  4YSL A;  5EVB A;  5HH4 A;  2Q0J A;  2BTN A;  3BK1 A;  4GYQ A;  1WUO A;  1X8G A;  3Q6V A;  1YCH A;  3DH8 A;  2NZE A;  2CBN A;  3ADR A;  2I7V A;  1DXK A;  3VQZ A;  4TYT A;  2Y87 A;  3IEL A;  4RBS A;  2Q0I A;  4AD9 A;  4DIL A;  3I14 A;  1MQO A;  2GCU A;  3IE2 A;  4FSB A;  2AIO A;  2BG8 B;  5LM6 A;  2H6A A;  3T3N A;  4UWO B;  2BFZ A;  4PVO A;  4EYF A;  4C1F A;  2P97 A;  2R2D A;  3RPC A;  3DHB A;  4ZEJ A;  1YCF A;  1DD6 A;  4H0D A;  5KIK A;  2BFK A;  4ZNB A;  4F6Z A;  5EVK A;  4TZ9 A;  1VME A;  3F9O A;  4RAM A;  3T9M A;  4C1E A;  5K4M A;  4RL2 A;  4UBQ A;  5HIQ A;  3R2U A;  4J5H A;  2Q9U A;  4C1C A;  4NQ2 A;  5B15 A;  3IDZ A;  4UWR B;  2Q42 A;  4NQ5 A;  3BC2 A;  5LCA A;  2FM6 A;  2WHG A;  4GYU A;  1WW1 A;  1Y44 A;  5HIO A;  4XUK A;  2BG7 A;  2FU7 A;  4UWS B;  1SML A;  2NXA A;  3A4Y A;  1E5D A;  3KL7 A;  5EH9 A;  1VJN A;  1WUP A;  1HLK A;  4Z7R A;  4EXS A;  4Z5Y A;  4HKY A;  2YNT B;  2BGA A;  3MD7 A;  2WYL A;  5A87 A;  2BG6 A;  3G1P A;  4RL0 A;  4YSB A;  5LS3 A;  2HB9 A;  2I7T A;  4EYB A;  4EYL A;  2WYM C;  2I7X A;  5AXO A;  4UA4 A;  1X8I A;  1BVT A;  5HIS A;  1YCG A;  4KEP A;  4O98 A;  1WRA A;  4U4L A;  5ACV A;  4C1G A;  5EVD A;  2OHH A;  3WXC A;  3BV6 A;  1KR3 A;  4RAW A;  2DKF A;  2YNV A;  4V0H A;  2QDS A;  5A5Z A;  5LE1 A;  5FQA A;  4FR7 A;  4ZO3 A;  3S0Z A;  1ZTC A;  2XR1 A;  2BFL A;  4AX1 B;  2XF4 A;  1BMC A;  2FHX A;  5DPX A;  3VPE A;  5K4N A;  2A7M A;  2FU6 A;  2ZNB A;  2Y8A A;  3AF5 A;  2ZO4 A;  2GKL A;  2E7Y A;  3BK2 A;  4Z67 A;  5ACS A;  2QJS A;  5EWA A;  4NQ6 A;  5HIP A;  5AYA A;  5FQB A;  4FEK A;  1K07 A;  4CHL A;  3RKJ A;  3SBL A;  2BFZ B;  3L6N A;  4J5F A;  1P9E A;  5EW0 A;  5ACU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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