5ACUA

Vim-2-nat, discovery of novel inhibitor scaffolds against the metallo- beta-lactamase vim-2 by spr based fragment screening
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
231
structure length
230
Chain Sequence
GEYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords BETA-LACTAMASE
publication title Discovery of Novel Inhibitor Scaffolds Against the Metallo-Beta-Lactamase Vim-2 by Spr Based Fragment Screening
pubmed doi rcsb
source organism Pseudomonas aeruginosa
total genus 64
structure length 230
sequence length 231
ec nomenclature ec 3.5.2.6: Beta-lactamase.
pdb deposition date 2015-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5acuA00
5ACPA 2DKFA 3IE1A 1E5DA 2WYMC 4Z7RA 4TZ9A 1L9YA 1KO3A 4J5HA 3ZR9A 1BVTA 2QDTA 1A7TA 1WUOA 2NXAA 4EY2A 4WD6A 5K0WA 3IOFA 4RM5A 4F6ZA 1KO2A 3JXPA 1JJTA 4UAMA 1ZTCA 5AYAA 4YSKA 2YZ3A 4BP0A 1HLKA 4Z5YA 5K4NA 3I15A 2BG8A 4XWWA 1X8IA 4Z6XA 2Q42A 3ZWFA 3PG4A 4RAMA 2YNTA 5HH4A 4F6HA 2GFJA 4GYUA 2I7XA 2NZEA 3FCZA 1ZNBA 3IEMA 2BIBA 2FU8A 2XF4A 3KL7A 5IQKA 5ACUA 3P2UA 2GFKA 2BR6A 4HL2A 5LS3A 2BTNA 3SBLA 5LM6A 4NQ2A 3BK2A 2GCUA 3DH8A 5FQCA 3AF5A 2NYPA 4D1TA 4TZFA 4EYBA 5K4MA 2YNVB 2BGAA 4RL2A 4O98A 4UWPB 4H0DA 5EHTA 5ACXA 4C1HA 5A0VA 1MQOA 1A8TA 1P9EA 5B3RA 2FK6A 3I13A 5LCFA 3SRXA 5EWAA 1VJNA 3R2UA 3MD7A 5DPXA 3X2XA 3TP9A 3X2YA 1QH3A 2WRSA 2OHHA 4ZO2A 1YCGA 3S0ZA 1QH5A 2Q0JA 5EV6A 1VMEA 1JJEA 2ZNBA 1DXKA 5K4KA 2WYMA 2ZWRA 2DOOA 4XUKA 5AHOA 3X30A 4Z67A 5LE1A 3IOGA 4UWSB 5LMCA 2NZFA 2FU7A 2P1EA 3G1PA 3IE0A 5ACVA 4D1VA 5HIQA 3BV6A 3QH8A 5A0TA 2YNVA 5FQBA 1DD6A 4EXYA 3T3OA 2Q0IA 2GKLA 3WXCA 4C1CA 4NQ6A 3AJ3A 4J5FA 3VQZA 4EXSA 5A87A 4EYLA 4C1EA 2WHGA 4YSLA 1KR3A 5AHRA 4RL0A 4LE6A 4TYTA 3LVZA 3PY6A 2H6AA 2FU6A 4V0HA 5EVBA 2M5CA 5EW0A 5FQAA 2P97A 4D02A 4UBQA 2Y87A 2FM6A 1X8HA 2QEDA 4NQ4A 4FR7A 5ACSA 4KEQA 3SFPA 5ACQA 4DILA 4D1UA 2HB9A 4RBSA 4C1DA 4AWYB 4P62A 5ACTA 5KILA 3Q6VA 4D1WA 5HISA 5LSCA 3I0VA 2FHXB 3IEKA 4TZBA 5A5ZA 4ZNBA 4KEPA 4AWZA 1YCHA 2OHJA 2GMNA 4Z60A 5LCAA 2VW8A 2M5DA 4DIKA 4U4LA 2YNWA 4CHLA 4B87A 5EVDA 4ZEJA 5KIKA 5HIPA 2I7VA 5AXOA 1DDKA 3SPUA 4Z5ZA 2WYLA 5LCHA 3T3NA 5B15A 3AF6A 1ZKPA 5HH5A 1SMLA 2XR1A 3DHAA 1WRAA 2QINA 2BFZA 3IELA 5EV8A 4TZEA 1WW1A 5AXRA 3SD9A 3I11A 2BFKA 3BK1A 1WUPA 4HL1A 4ZO3A 4GYQA 2CBNA 2FHXA 3H3EA 5ACWA 3KNSA 1JT1A 4AX1B 2Y8BA 2ZO4A 3SW3A 2BG2A 3RKJA 4PVTA 2P18A 5B1UA 2FU9A 2AIOA 3DHCA 1BMCA 3A4YA 2QDSA 3I14A 4JO0A 3ADRA 3PY5A 4EYFA 4UWOB 3T9MA 4BZ3A 2UYXA 3IDZA 1BC2A 1Y44A 4YSBA 5LLDA 3IE2A 2E7YA 1VGNA 2BFZB 5ACRA 4RAWA 4GCWA 3KNRA 2P4ZA 2BG6A 4C09A 3VPEA 4TYFA 2YNUA 2Y8AA 4AD9A 2A7MA 4XWTA 4FSBA 5HIOA 4EFZA 2R2DA 1XM8A 3ESHA 4HKYA 3F9OA 2OHIA 3FAIA 2QJSA 1XTOA 2YCBA 1M2XA 4AX0B 3RKKA 4C1GA 4NQ5A 4UWRB 4UA4A 3BC2A 2ZZIA 3L6NA 2AZ4A 1YCFA 2BG7A 2BMIA 2BFLA 2Q9UA 2BG8B 3DHBA 4FEKA 3ZQ4A 5HH6A 1X8GA 4C1FA 1K07A 4PVOA 5EH9A 2YNTB 5EVKA 5AEBA 2BC2A 3ZNBA 2I7TA 3RPCA 3X2ZA
chains in the Genus database with same CATH superfamily
5ACPA 5AJLA 2DKFA 3IE1A 1E5DA 2WYMC 4Z7RA 4TZ9A 1L9YA 1KO3A 4J5HA 3ZR9A 1BVTA 2QDTA 1A7TA 1WUOA 2NXAA 4EY2A 4WD6A 5K0WA 3IOFA 4RM5A 4F6ZA 1KO2A 3JXPA 1JJTA 4UAMA 1ZTCA 5AYAA 4YSKA 2YZ3A 4BP0A 1HLKA 4Z5YA 5K4NA 3I15A 2BG8A 4XWWA 1X8IA 4Z6XA 2Q42A 3ZWFA 3PG4A 4RAMA 2YNTA 5HH4A 4F6HA 2GFJA 4GYUA 2I7XA 2NZEA 3FCZA 1ZNBA 3IEMA 2BIBA 2FU8A 2XF4A 3KL7A 5IQKA 5ACUA 3P2UA 2GFKA 2BR6A 4HL2A 5LS3A 2BTNA 3SBLA 5LM6A 4NQ2A 3BK2A 2GCUA 2CG2A 3DH8A 5FQCA 3AF5A 2NYPA 4D1TA 4TZFA 5K4MA 4EYBA 2YNVB 2BGAA 4RL2A 4O98A 4UWPB 4H0DA 5EHTA 5ACXA 4C1HA 5A0VA 1MQOA 5AIJA 1A8TA 1P9EA 5B3RA 4AXHA 2FK6A 3I13A 5LCFA 3SRXA 5EWAA 1VJNA 3R2UA 3MD7A 5DPXA 4AV7A 3X2XA 3TP9A 3X2YA 1QH3A 2WRSA 2OHHA 4ZO2A 1YCGA 3S0ZA 1QH5A 2Q0JA 2CFZA 5EV6A 4NURA 1VMEA 1JJEA 2ZNBA 1DXKA 5K4KA 2WYMA 2ZWRA 2DOOA 4XUKA 5AHOA 3X30A 4Z67A 5LE1A 3IOGA 4UWSB 5LMCA 2NZFA 2FU7A 2P1EA 3G1PA 3IE0A 5ACVA 4D1VA 5HIQA 3BV6A 3QH8A 5A0TA 2YNVA 5FQBA 1DD6A 4EXYA 3T3OA 2Q0IA 2GKLA 3WXCA 4C1CA 4NQ6A 3AJ3A 4J5FA 3VQZA 4EXSA 5A87A 4EYLA 4C1EA 2WHGA 4YSLA 1KR3A 5AHRA 4RL0A 4LE6A 5A23A 4TYTA 3LVZA 3PY6A 2H6AA 2FU6A 4V0HA 5EVBA 2M5CA 5EW0A 5FQAA 2P97A 4D02A 4UBQA 2Y87A 2FM6A 1X8HA 2QEDA 4NQ4A 4FR7A 5ACSA 4KEQA 3SFPA 5ACQA 4DILA 4D1UA 2HB9A 4RBSA 4C1DA 4AWYB 4P62A 5ACTA 5KILA 3Q6VA 4D1WA 5HISA 5LSCA 3I0VA 2FHXB 3IEKA 4TZBA 5A5ZA 4ZNBA 4KEPA 4AWZA 1YCHA 2OHJA 2GMNA 4Z60A 5LCAA 2VW8A 2M5DA 4DIKA 4U4LA 2YNWA 4CHLA 4B87A 5EVDA 4ZEJA 5KIKA 5HIPA 2I7VA 5AXOA 1DDKA 3SPUA 4Z5ZA 2WYLA 5LCHA 3T3NA 5B15A 3AF6A 1ZKPA 5HH5A 1SMLA 2XR1A 3DHAA 1WRAA 2QINA 2BFZA 3IELA 5EV8A 4TZEA 1WW1A 5AXRA 3SD9A 3I11A 2BFKA 3BK1A 1WUPA 4HL1A 4ZO3A 4GYQA 2CBNA 2FHXA 3H3EA 5ACWA 3KNSA 1JT1A 4AX1B 2Y8BA 2ZO4A 3SW3A 2BG2A 4PDXA 3RKJA 4PVTA 2P18A 5B1UA 2FU9A 2AIOA 3DHCA 1BMCA 3A4YA 2QDSA 3I14A 4JO0A 3ADRA 3PY5A 4EYFA 2CFUA 4UWOB 3T9MA 4BZ3A 2UYXA 2YHEA 3IDZA 1BC2A 1Y44A 4YSBA 5LLDA 3IE2A 2E7YA 1VGNA 2BFZB 5ACRA 4RAWA 4GCWA 3KNRA 2P4ZA 2BG6A 4C09A 3VPEA 4TYFA 2YNUA 2Y8AA 4AD9A 2A7MA 4XWTA 4FSBA 5HIOA 4EFZA 2R2DA 1XM8A 3ESHA 4HKYA 3F9OA 2OHIA 3FAIA 2QJSA 1XTOA 2YCBA 1M2XA 2CG3A 4AX0B 3RKKA 4C1GA 4NQ5A 4UWRB 4UA4A 3BC2A 2ZZIA 3L6NA 2AZ4A 1YCFA 2BG7A 2BMIA 2BFLA 2Q9UA 2BG8B 3DHBA 4FEKA 3ZQ4A 5HH6A 1X8GA 4C1FA 1K07A 4PVOA 5EH9A 2YNTB 5EVKA 5AEBA 2BC2A 3ZNBA 2I7TA 3RPCA 3X2ZA
chains in the Genus database with same CATH topology
5ACPA 2DKFA 3IE1A 1E5DA 2WYMC 4Z7RA 4TZ9A 1L9YA 1KO3A 4J5HA 3ZR9A 1BVTA 2QDTA 1A7TA 1WUOA 2NXAA 4EY2A 4WD6A 5K0WA 3IOFA 4RM5A 4F6ZA 1KO2A 3JXPA 1JJTA 4UAMA 1ZTCA 5AYAA 4YSKA 2YZ3A 4BP0A 1HLKA 4Z5YA 5K4NA 3I15A 2BG8A 4XWWA 1X8IA 4Z6XA 2Q42A 3ZWFA 3PG4A 4RAMA 2YNTA 5HH4A 4F6HA 2GFJA 4GYUA 2I7XA 2NZEA 3FCZA 1ZNBA 3IEMA 2BIBA 2FU8A 2XF4A 3KL7A 5IQKA 5ACUA 3P2UA 2GFKA 2BR6A 4HL2A 5LS3A 2BTNA 3SBLA 5LM6A 4NQ2A 3BK2A 2GCUA 3DH8A 5FQCA 3AF5A 2NYPA 4D1TA 4TZFA 4EYBA 5K4MA 2YNVB 2BGAA 4RL2A 4O98A 4UWPB 4H0DA 5EHTA 5ACXA 4C1HA 5A0VA 1MQOA 1A8TA 1P9EA 5B3RA 2FK6A 3I13A 5LCFA 3SRXA 5EWAA 1VJNA 3R2UA 3MD7A 5DPXA 3X2XA 3TP9A 3X2YA 1QH3A 2WRSA 2OHHA 4ZO2A 1YCGA 3S0ZA 1QH5A 2Q0JA 5EV6A 1VMEA 1JJEA 2ZNBA 1DXKA 5K4KA 2WYMA 2ZWRA 2DOOA 4XUKA 5AHOA 3X30A 4Z67A 5LE1A 3IOGA 4UWSB 5LMCA 2NZFA 2FU7A 2P1EA 3G1PA 3IE0A 5ACVA 4D1VA 5HIQA 3BV6A 3QH8A 5A0TA 2YNVA 5FQBA 1DD6A 4EXYA 3T3OA 2Q0IA 2GKLA 3WXCA 4C1CA 4NQ6A 3AJ3A 4J5FA 3VQZA 4EXSA 5A87A 4EYLA 4C1EA 2WHGA 4YSLA 1KR3A 5AHRA 4RL0A 4LE6A 4TYTA 3LVZA 3PY6A 2H6AA 2FU6A 4V0HA 5EVBA 2M5CA 5EW0A 5FQAA 2P97A 4D02A 4UBQA 2Y87A 2FM6A 1X8HA 2QEDA 4NQ4A 4FR7A 5ACSA 4KEQA 3SFPA 5ACQA 4DILA 4D1UA 2HB9A 4RBSA 4C1DA 4AWYB 4P62A 5ACTA 5KILA 3Q6VA 4D1WA 5HISA 5LSCA 3I0VA 2FHXB 3IEKA 4TZBA 5A5ZA 4ZNBA 4KEPA 4AWZA 1YCHA 2OHJA 2GMNA 4Z60A 5LCAA 2VW8A 2M5DA 4DIKA 4U4LA 2YNWA 4CHLA 4B87A 5EVDA 4ZEJA 5KIKA 5HIPA 2I7VA 5AXOA 1DDKA 3SPUA 4Z5ZA 2WYLA 5LCHA 3T3NA 5B15A 3AF6A 1ZKPA 5HH5A 1SMLA 2XR1A 3DHAA 1WRAA 2QINA 2BFZA 3IELA 5EV8A 4TZEA 1WW1A 5AXRA 3SD9A 3I11A 2BFKA 3BK1A 1WUPA 4HL1A 4ZO3A 4GYQA 2CBNA 2FHXA 3H3EA 5ACWA 3KNSA 1JT1A 4AX1B 2Y8BA 2ZO4A 3SW3A 2BG2A 3RKJA 4PVTA 2P18A 5B1UA 2FU9A 2AIOA 3DHCA 1BMCA 3A4YA 2QDSA 3I14A 4JO0A 3ADRA 3PY5A 4EYFA 4UWOB 3T9MA 4BZ3A 2UYXA 3IDZA 1BC2A 1Y44A 4YSBA 5LLDA 3IE2A 2E7YA 1VGNA 2BFZB 5ACRA 4RAWA 4GCWA 3KNRA 2P4ZA 2BG6A 4C09A 3VPEA 4TYFA 2YNUA 2Y8AA 4AD9A 2A7MA 4XWTA 4FSBA 5HIOA 4EFZA 2R2DA 1XM8A 3ESHA 4HKYA 3F9OA 2OHIA 3FAIA 2QJSA 1XTOA 2YCBA 1M2XA 4AX0B 3RKKA 4C1GA 4NQ5A 4UWRB 4UA4A 3BC2A 2ZZIA 3L6NA 2AZ4A 1YCFA 2BG7A 2BMIA 2BFLA 2Q9UA 2BG8B 3DHBA 4FEKA 3ZQ4A 5HH6A 1X8GA 4C1FA 1K07A 4PVOA 5EH9A 2YNTB 5EVKA 5AEBA 2BC2A 3ZNBA 2I7TA 3RPCA 3X2ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5ACP A;  2DKF A;  3IE1 A;  1E5D A;  2WYM C;  4Z7R A;  4TZ9 A;  1L9Y A;  1KO3 A;  4J5H A;  3ZR9 A;  1BVT A;  2QDT A;  1A7T A;  1WUO A;  2NXA A;  4EY2 A;  4WD6 A;  5K0W A;  3IOF A;  4RM5 A;  4F6Z A;  1KO2 A;  3JXP A;  1JJT A;  4UAM A;  1ZTC A;  5AYA A;  4YSK A;  2YZ3 A;  4BP0 A;  1HLK A;  4Z5Y A;  5K4N A;  3I15 A;  2BG8 A;  4XWW A;  1X8I A;  4Z6X A;  2Q42 A;  3ZWF A;  3PG4 A;  4RAM A;  2YNT A;  5HH4 A;  4F6H A;  2GFJ A;  4GYU A;  2I7X A;  2NZE A;  3FCZ A;  1ZNB A;  3IEM A;  2BIB A;  2FU8 A;  2XF4 A;  3KL7 A;  5IQK A;  5ACU A;  3P2U A;  2GFK A;  2BR6 A;  4HL2 A;  5LS3 A;  2BTN A;  3SBL A;  5LM6 A;  4NQ2 A;  3BK2 A;  2GCU A;  3DH8 A;  5FQC A;  3AF5 A;  2NYP A;  4D1T A;  4TZF A;  4EYB A;  5K4M A;  2YNV B;  2BGA A;  4RL2 A;  4O98 A;  4UWP B;  4H0D A;  5EHT A;  5ACX A;  4C1H A;  5A0V A;  1MQO A;  1A8T A;  1P9E A;  5B3R A;  2FK6 A;  3I13 A;  5LCF A;  3SRX A;  5EWA A;  1VJN A;  3R2U A;  3MD7 A;  5DPX A;  3X2X A;  3TP9 A;  3X2Y A;  1QH3 A;  2WRS A;  2OHH A;  4ZO2 A;  1YCG A;  3S0Z A;  1QH5 A;  2Q0J A;  5EV6 A;  1VME A;  1JJE A;  2ZNB A;  1DXK A;  5K4K A;  2WYM A;  2ZWR A;  2DOO A;  4XUK A;  5AHO A;  3X30 A;  4Z67 A;  5LE1 A;  3IOG A;  4UWS B;  5LMC A;  2NZF A;  2FU7 A;  2P1E A;  3G1P A;  3IE0 A;  5ACV A;  4D1V A;  5HIQ A;  3BV6 A;  3QH8 A;  5A0T A;  2YNV A;  5FQB A;  1DD6 A;  4EXY A;  3T3O A;  2Q0I A;  2GKL A;  3WXC A;  4C1C A;  4NQ6 A;  3AJ3 A;  4J5F A;  3VQZ A;  4EXS A;  5A87 A;  4EYL A;  4C1E A;  2WHG A;  4YSL A;  1KR3 A;  5AHR A;  4RL0 A;  4LE6 A;  4TYT A;  3LVZ A;  3PY6 A;  2H6A A;  2FU6 A;  4V0H A;  5EVB A;  2M5C A;  5EW0 A;  5FQA A;  2P97 A;  4D02 A;  4UBQ A;  2Y87 A;  2FM6 A;  1X8H A;  2QED A;  4NQ4 A;  4FR7 A;  5ACS A;  4KEQ A;  3SFP A;  5ACQ A;  4DIL A;  4D1U A;  2HB9 A;  4RBS A;  4C1D A;  4AWY B;  4P62 A;  5ACT A;  5KIL A;  3Q6V A;  4D1W A;  5HIS A;  5LSC A;  3I0V A;  2FHX B;  3IEK A;  4TZB A;  5A5Z A;  4ZNB A;  4KEP A;  4AWZ A;  1YCH A;  2OHJ A;  2GMN A;  4Z60 A;  5LCA A;  2VW8 A;  2M5D A;  4DIK A;  4U4L A;  2YNW A;  4CHL A;  4B87 A;  5EVD A;  4ZEJ A;  5KIK A;  5HIP A;  2I7V A;  5AXO A;  1DDK A;  3SPU A;  4Z5Z A;  2WYL A;  5LCH A;  3T3N A;  5B15 A;  3AF6 A;  1ZKP A;  5HH5 A;  1SML A;  2XR1 A;  3DHA A;  1WRA A;  2QIN A;  2BFZ A;  3IEL A;  5EV8 A;  4TZE A;  1WW1 A;  5AXR A;  3SD9 A;  3I11 A;  2BFK A;  3BK1 A;  1WUP A;  4HL1 A;  4ZO3 A;  4GYQ A;  2CBN A;  2FHX A;  3H3E A;  5ACW A;  3KNS A;  1JT1 A;  4AX1 B;  2Y8B A;  2ZO4 A;  3SW3 A;  2BG2 A;  3RKJ A;  4PVT A;  2P18 A;  5B1U A;  2FU9 A;  2AIO A;  3DHC A;  1BMC A;  3A4Y A;  2QDS A;  3I14 A;  4JO0 A;  3ADR A;  3PY5 A;  4EYF A;  4UWO B;  3T9M A;  4BZ3 A;  2UYX A;  3IDZ A;  1BC2 A;  1Y44 A;  4YSB A;  5LLD A;  3IE2 A;  2E7Y A;  1VGN A;  2BFZ B;  5ACR A;  4RAW A;  4GCW A;  3KNR A;  2P4Z A;  2BG6 A;  4C09 A;  3VPE A;  4TYF A;  2YNU A;  2Y8A A;  4AD9 A;  2A7M A;  4XWT A;  4FSB A;  5HIO A;  4EFZ A;  2R2D A;  1XM8 A;  3ESH A;  4HKY A;  3F9O A;  2OHI A;  3FAI A;  2QJS A;  1XTO A;  2YCB A;  1M2X A;  4AX0 B;  3RKK A;  4C1G A;  4NQ5 A;  4UWR B;  4UA4 A;  3BC2 A;  2ZZI A;  3L6N A;  2AZ4 A;  1YCF A;  2BG7 A;  2BMI A;  2BFL A;  2Q9U A;  2BG8 B;  3DHB A;  4FEK A;  3ZQ4 A;  5HH6 A;  1X8G A;  4C1F A;  1K07 A;  4PVO A;  5EH9 A;  2YNT B;  5EVK A;  5AEB A;  2BC2 A;  3ZNB A;  2I7T A;  3RPC A;  3X2Z A; 
#chains in the Genus database with same CATH topology
 5ACP A;  5AJL A;  2DKF A;  3IE1 A;  1E5D A;  2WYM C;  4Z7R A;  4TZ9 A;  1L9Y A;  1KO3 A;  4J5H A;  3ZR9 A;  1BVT A;  2QDT A;  1A7T A;  1WUO A;  2NXA A;  4EY2 A;  4WD6 A;  5K0W A;  3IOF A;  4RM5 A;  4F6Z A;  1KO2 A;  3JXP A;  1JJT A;  4UAM A;  1ZTC A;  5AYA A;  4YSK A;  2YZ3 A;  4BP0 A;  1HLK A;  4Z5Y A;  5K4N A;  3I15 A;  2BG8 A;  4XWW A;  1X8I A;  4Z6X A;  2Q42 A;  3ZWF A;  3PG4 A;  4RAM A;  2YNT A;  5HH4 A;  4F6H A;  2GFJ A;  4GYU A;  2I7X A;  2NZE A;  3FCZ A;  1ZNB A;  3IEM A;  2BIB A;  2FU8 A;  2XF4 A;  3KL7 A;  5IQK A;  5ACU A;  3P2U A;  2GFK A;  2BR6 A;  4HL2 A;  5LS3 A;  2BTN A;  3SBL A;  5LM6 A;  4NQ2 A;  3BK2 A;  2GCU A;  2CG2 A;  3DH8 A;  5FQC A;  3AF5 A;  2NYP A;  4D1T A;  4TZF A;  5K4M A;  4EYB A;  2YNV B;  2BGA A;  4RL2 A;  4O98 A;  4UWP B;  4H0D A;  5EHT A;  5ACX A;  4C1H A;  5A0V A;  1MQO A;  5AIJ A;  1A8T A;  1P9E A;  5B3R A;  4AXH A;  2FK6 A;  3I13 A;  5LCF A;  3SRX A;  5EWA A;  1VJN A;  3R2U A;  3MD7 A;  5DPX A;  4AV7 A;  3X2X A;  3TP9 A;  3X2Y A;  1QH3 A;  2WRS A;  2OHH A;  4ZO2 A;  1YCG A;  3S0Z A;  1QH5 A;  2Q0J A;  2CFZ A;  5EV6 A;  4NUR A;  1VME A;  1JJE A;  2ZNB A;  1DXK A;  5K4K A;  2WYM A;  2ZWR A;  2DOO A;  4XUK A;  5AHO A;  3X30 A;  4Z67 A;  5LE1 A;  3IOG A;  4UWS B;  5LMC A;  2NZF A;  2FU7 A;  2P1E A;  3G1P A;  3IE0 A;  5ACV A;  4D1V A;  5HIQ A;  3BV6 A;  3QH8 A;  5A0T A;  2YNV A;  5FQB A;  1DD6 A;  4EXY A;  3T3O A;  2Q0I A;  2GKL A;  3WXC A;  4C1C A;  4NQ6 A;  3AJ3 A;  4J5F A;  3VQZ A;  4EXS A;  5A87 A;  4EYL A;  4C1E A;  2WHG A;  4YSL A;  1KR3 A;  5AHR A;  4RL0 A;  4LE6 A;  5A23 A;  4TYT A;  3LVZ A;  3PY6 A;  2H6A A;  2FU6 A;  4V0H A;  5EVB A;  2M5C A;  5EW0 A;  5FQA A;  2P97 A;  4D02 A;  4UBQ A;  2Y87 A;  2FM6 A;  1X8H A;  2QED A;  4NQ4 A;  4FR7 A;  5ACS A;  4KEQ A;  3SFP A;  5ACQ A;  4DIL A;  4D1U A;  2HB9 A;  4RBS A;  4C1D A;  4AWY B;  4P62 A;  5ACT A;  5KIL A;  3Q6V A;  4D1W A;  5HIS A;  5LSC A;  3I0V A;  2FHX B;  3IEK A;  4TZB A;  5A5Z A;  4ZNB A;  4KEP A;  4AWZ A;  1YCH A;  2OHJ A;  2GMN A;  4Z60 A;  5LCA A;  2VW8 A;  2M5D A;  4DIK A;  4U4L A;  2YNW A;  4CHL A;  4B87 A;  5EVD A;  4ZEJ A;  5KIK A;  5HIP A;  2I7V A;  5AXO A;  1DDK A;  3SPU A;  4Z5Z A;  2WYL A;  5LCH A;  3T3N A;  5B15 A;  3AF6 A;  1ZKP A;  5HH5 A;  1SML A;  2XR1 A;  3DHA A;  1WRA A;  2QIN A;  2BFZ A;  3IEL A;  5EV8 A;  4TZE A;  1WW1 A;  5AXR A;  3SD9 A;  3I11 A;  2BFK A;  3BK1 A;  1WUP A;  4HL1 A;  4ZO3 A;  4GYQ A;  2CBN A;  2FHX A;  3H3E A;  5ACW A;  3KNS A;  1JT1 A;  4AX1 B;  2Y8B A;  2ZO4 A;  3SW3 A;  2BG2 A;  4PDX A;  3RKJ A;  4PVT A;  2P18 A;  5B1U A;  2FU9 A;  2AIO A;  3DHC A;  1BMC A;  3A4Y A;  2QDS A;  3I14 A;  4JO0 A;  3ADR A;  3PY5 A;  4EYF A;  2CFU A;  4UWO B;  3T9M A;  4BZ3 A;  2UYX A;  2YHE A;  3IDZ A;  1BC2 A;  1Y44 A;  4YSB A;  5LLD A;  3IE2 A;  2E7Y A;  1VGN A;  2BFZ B;  5ACR A;  4RAW A;  4GCW A;  3KNR A;  2P4Z A;  2BG6 A;  4C09 A;  3VPE A;  4TYF A;  2YNU A;  2Y8A A;  4AD9 A;  2A7M A;  4XWT A;  4FSB A;  5HIO A;  4EFZ A;  2R2D A;  1XM8 A;  3ESH A;  4HKY A;  3F9O A;  2OHI A;  3FAI A;  2QJS A;  1XTO A;  2YCB A;  1M2X A;  2CG3 A;  4AX0 B;  3RKK A;  4C1G A;  4NQ5 A;  4UWR B;  4UA4 A;  3BC2 A;  2ZZI A;  3L6N A;  2AZ4 A;  1YCF A;  2BG7 A;  2BMI A;  2BFL A;  2Q9U A;  2BG8 B;  3DHB A;  4FEK A;  3ZQ4 A;  5HH6 A;  1X8G A;  4C1F A;  1K07 A;  4PVO A;  5EH9 A;  2YNT B;  5EVK A;  5AEB A;  2BC2 A;  3ZNB A;  2I7T A;  3RPC A;  3X2Z A; 
#chains in the Genus database with same CATH homology
 5ACP A;  2DKF A;  3IE1 A;  1E5D A;  2WYM C;  4Z7R A;  4TZ9 A;  1L9Y A;  1KO3 A;  4J5H A;  3ZR9 A;  1BVT A;  2QDT A;  1A7T A;  1WUO A;  2NXA A;  4EY2 A;  4WD6 A;  5K0W A;  3IOF A;  4RM5 A;  4F6Z A;  1KO2 A;  3JXP A;  1JJT A;  4UAM A;  1ZTC A;  5AYA A;  4YSK A;  2YZ3 A;  4BP0 A;  1HLK A;  4Z5Y A;  5K4N A;  3I15 A;  2BG8 A;  4XWW A;  1X8I A;  4Z6X A;  2Q42 A;  3ZWF A;  3PG4 A;  4RAM A;  2YNT A;  5HH4 A;  4F6H A;  2GFJ A;  4GYU A;  2I7X A;  2NZE A;  3FCZ A;  1ZNB A;  3IEM A;  2BIB A;  2FU8 A;  2XF4 A;  3KL7 A;  5IQK A;  5ACU A;  3P2U A;  2GFK A;  2BR6 A;  4HL2 A;  5LS3 A;  2BTN A;  3SBL A;  5LM6 A;  4NQ2 A;  3BK2 A;  2GCU A;  3DH8 A;  5FQC A;  3AF5 A;  2NYP A;  4D1T A;  4TZF A;  4EYB A;  5K4M A;  2YNV B;  2BGA A;  4RL2 A;  4O98 A;  4UWP B;  4H0D A;  5EHT A;  5ACX A;  4C1H A;  5A0V A;  1MQO A;  1A8T A;  1P9E A;  5B3R A;  2FK6 A;  3I13 A;  5LCF A;  3SRX A;  5EWA A;  1VJN A;  3R2U A;  3MD7 A;  5DPX A;  3X2X A;  3TP9 A;  3X2Y A;  1QH3 A;  2WRS A;  2OHH A;  4ZO2 A;  1YCG A;  3S0Z A;  1QH5 A;  2Q0J A;  5EV6 A;  1VME A;  1JJE A;  2ZNB A;  1DXK A;  5K4K A;  2WYM A;  2ZWR A;  2DOO A;  4XUK A;  5AHO A;  3X30 A;  4Z67 A;  5LE1 A;  3IOG A;  4UWS B;  5LMC A;  2NZF A;  2FU7 A;  2P1E A;  3G1P A;  3IE0 A;  5ACV A;  4D1V A;  5HIQ A;  3BV6 A;  3QH8 A;  5A0T A;  2YNV A;  5FQB A;  1DD6 A;  4EXY A;  3T3O A;  2Q0I A;  2GKL A;  3WXC A;  4C1C A;  4NQ6 A;  3AJ3 A;  4J5F A;  3VQZ A;  4EXS A;  5A87 A;  4EYL A;  4C1E A;  2WHG A;  4YSL A;  1KR3 A;  5AHR A;  4RL0 A;  4LE6 A;  4TYT A;  3LVZ A;  3PY6 A;  2H6A A;  2FU6 A;  4V0H A;  5EVB A;  2M5C A;  5EW0 A;  5FQA A;  2P97 A;  4D02 A;  4UBQ A;  2Y87 A;  2FM6 A;  1X8H A;  2QED A;  4NQ4 A;  4FR7 A;  5ACS A;  4KEQ A;  3SFP A;  5ACQ A;  4DIL A;  4D1U A;  2HB9 A;  4RBS A;  4C1D A;  4AWY B;  4P62 A;  5ACT A;  5KIL A;  3Q6V A;  4D1W A;  5HIS A;  5LSC A;  3I0V A;  2FHX B;  3IEK A;  4TZB A;  5A5Z A;  4ZNB A;  4KEP A;  4AWZ A;  1YCH A;  2OHJ A;  2GMN A;  4Z60 A;  5LCA A;  2VW8 A;  2M5D A;  4DIK A;  4U4L A;  2YNW A;  4CHL A;  4B87 A;  5EVD A;  4ZEJ A;  5KIK A;  5HIP A;  2I7V A;  5AXO A;  1DDK A;  3SPU A;  4Z5Z A;  2WYL A;  5LCH A;  3T3N A;  5B15 A;  3AF6 A;  1ZKP A;  5HH5 A;  1SML A;  2XR1 A;  3DHA A;  1WRA A;  2QIN A;  2BFZ A;  3IEL A;  5EV8 A;  4TZE A;  1WW1 A;  5AXR A;  3SD9 A;  3I11 A;  2BFK A;  3BK1 A;  1WUP A;  4HL1 A;  4ZO3 A;  4GYQ A;  2CBN A;  2FHX A;  3H3E A;  5ACW A;  3KNS A;  1JT1 A;  4AX1 B;  2Y8B A;  2ZO4 A;  3SW3 A;  2BG2 A;  3RKJ A;  4PVT A;  2P18 A;  5B1U A;  2FU9 A;  2AIO A;  3DHC A;  1BMC A;  3A4Y A;  2QDS A;  3I14 A;  4JO0 A;  3ADR A;  3PY5 A;  4EYF A;  4UWO B;  3T9M A;  4BZ3 A;  2UYX A;  3IDZ A;  1BC2 A;  1Y44 A;  4YSB A;  5LLD A;  3IE2 A;  2E7Y A;  1VGN A;  2BFZ B;  5ACR A;  4RAW A;  4GCW A;  3KNR A;  2P4Z A;  2BG6 A;  4C09 A;  3VPE A;  4TYF A;  2YNU A;  2Y8A A;  4AD9 A;  2A7M A;  4XWT A;  4FSB A;  5HIO A;  4EFZ A;  2R2D A;  1XM8 A;  3ESH A;  4HKY A;  3F9O A;  2OHI A;  3FAI A;  2QJS A;  1XTO A;  2YCB A;  1M2X A;  4AX0 B;  3RKK A;  4C1G A;  4NQ5 A;  4UWR B;  4UA4 A;  3BC2 A;  2ZZI A;  3L6N A;  2AZ4 A;  1YCF A;  2BG7 A;  2BMI A;  2BFL A;  2Q9U A;  2BG8 B;  3DHB A;  4FEK A;  3ZQ4 A;  5HH6 A;  1X8G A;  4C1F A;  1K07 A;  4PVO A;  5EH9 A;  2YNT B;  5EVK A;  5AEB A;  2BC2 A;  3ZNB A;  2I7T A;  3RPC A;  3X2Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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