5ACUA

Vim-2-nat, discovery of novel inhibitor scaffolds against the metallo- beta-lactamase vim-2 by spr based fragment screening
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
231
structure length
230
Chain Sequence
GEYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords BETA-LACTAMASE
publication title Discovery of Novel Inhibitor Scaffolds Against the Metallo-Beta-Lactamase Vim-2 by Spr Based Fragment Screening
pubmed doi rcsb
source organism Pseudomonas aeruginosa
molecule tags Hydrolase
total genus 64
structure length 230
sequence length 231
ec nomenclature ec 3.5.2.6: Beta-lactamase.
pdb deposition date 2015-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5acuA00
5K4KA 2ZWRA 4UA4A 3KNSA 4Z7RA 3QH8A 4U4LA 1MQOA 2Q0JA 2BG8A 3JXPA 4GYUA 1A7TA 2GCUA 4NQ2A 2Y8BA 3DH8A 4AWYB 2OHIA 4XWTA 4TYFA 3BV6A 5DPXA 2WHGA 4TZ9A 4V0HA 4AX0B 2BR6A 3IE2A 2FHXA 1QH5A 4F6HA 4Z6XA 4TZFA 1WRAA 3IEMA 2BMIA 2YNTB 4YSBA 3DHBA 5A87A 4D1VA 5HIPA 4NQ5A 3I11A 4AD9A 2AZ4A 2DKFA 3Q6VA 3PY5A 4GYQA 5AEBA 3T3OA 4D1UA 2XF4A 5AHOA 2A7MA 1X8HA 4HL1A 1JJTA 1QH3A 3DHCA 4PVOA 2GMNA 3S0ZA 2BGAA 1KO2A 3L6NA 3ZNBA 1WW1A 2Q42A 5ACQA 4YSLA 4TZEA 5EV6A 2I7TA 1X8IA 5ACUA 1SMLA 2BTNA 2WYLA 3AJ3A 5LLDA 3IELA 4UWOB 5HISA 4FR7A 4UWRB 2NZEA 2OHJA 2OHHA 5IQKA 3X2XA 2AIOA 1YCFA 5B15A 3PG4A 5B3RA 2BFLA 2M5DA 3RPCA 3X2YA 2FM6A 1DXKA 4B87A 2Q9UA 2Y87A 1XTOA 3LVZA 3SBLA 2NZFA 2BG2A 3SPUA 3I14A 1A8TA 3AF5A 3T3NA 5LCFA 2ZZIA 4ZO3A 2FU7A 4H0DA 1YCGA 2BFZB 3VQZA 4O98A 4TYTA 4C1GA 2ZO4A 3IE0A 5K0WA 5K4MA 4EYBA 2P4ZA 3IOFA 1KR3A 5LCAA 3PY6A 1YCHA 2P1EA 4KEQA 4EYFA 1M2XA 5FQBA 2VW8A 2DOOA 2P97A 3T9MA 1DD6A 1XM8A 3I13A 1E5DA 2QJSA 3H3EA 2QINA 5A0TA 2WYMC 3IE1A 2QEDA 4C1FA 4C1CA 4XWWA 4AWZA 1KO3A 1BMCA 5AXRA 5HH6A 4ZO2A 4RL2A 4UWPB 2YNVB 3IOGA 2E7YA 5ACXA 5A0VA 3AF6A 1JT1A 3RKJA 1WUOA 4RAWA 5EVBA 3BK2A 5EW0A 1WUPA 5ACPA 4RBSA 2BG8B 4BP0A 3BC2A 1L9YA 5HIQA 4YSKA 2XR1A 1DDKA 3ESHA 5AHRA 1JJEA 4DIKA 5A5ZA 2FK6A 1X8GA 3MD7A 5ACWA 1ZNBA 3VPEA 2NYPA 2UYXA 3RKKA 2FHXB 4EFZA 2GKLA 2WRSA 4C09A 2YNTA 2YNUA 3I15A 5AYAA 5B1UA 4ZNBA 5EVKA 2YZ3A 2BG7A 3BK1A 5KIKA 4JO0A 4LE6A 5LS3A 4NQ4A 4UBQA 3F9OA 4C1DA 4C1EA 3I0VA 3IDZA 4UAMA 2YNWA 3FAIA 4FEKA 3X2ZA 3KL7A 3FCZA 3SRXA 1BC2A 3SFPA 2CBNA 4D02A 2QDSA 3ZR9A 1Y44A 4RM5A 4WD6A 4AX1B 2QDTA 2R2DA 2Y8AA 2GFJA 4CHLA 4UWSB 5LE1A 2BC2A 4GCWA 2FU9A 3A4YA 2YCBA 3IEKA 4RAMA 5LCHA 1ZKPA 2HB9A 2WYMA 1VGNA 4Z60A 2BFKA 4Z67A 1K07A 4FSBA 4KEPA 3SD9A 5EHTA 4HKYA 5KILA 2GFKA 3X30A 5EV8A 4EY2A 3KNRA 4F6ZA 5ACTA 2ZNBA 2I7VA 3ZQ4A 1P9EA 4D1WA 2BIBA 4Z5ZA 4Z5YA 5FQCA 2Q0IA 3ZWFA 2FU8A 4EXYA 5ACSA 2H6AA 2M5CA 2BFZA 1VMEA 3R2UA 3SW3A 2NXAA 4P62A 5FQAA 5EWAA 5EH9A 1BVTA 1VJNA 5LM6A 3P2UA 5HIOA 4EYLA 4EXSA 4BZ3A 3G1PA 5HH5A 5AXOA 3DHAA 5LSCA 5HH4A 2FU6A 4TZBA 4J5HA 4NQ6A 4RL0A 4D1TA 1HLKA 3ADRA 4DILA 4HL2A 4XUKA 3WXCA 4J5FA 5EVDA 2I7XA 5ACRA 3TP9A 2YNVA 1ZTCA 4PVTA 2P18A 4ZEJA 2BG6A 4C1HA 5K4NA 5LMCA 5ACVA
chains in the Genus database with same CATH superfamily
5K4KA 2ZWRA 4UA4A 3KNSA 4Z7RA 3QH8A 4U4LA 1MQOA 2Q0JA 2BG8A 3JXPA 4GYUA 1A7TA 2GCUA 4NQ2A 2Y8BA 3DH8A 4AWYB 2OHIA 4XWTA 4TYFA 3BV6A 5DPXA 2WHGA 4TZ9A 4V0HA 4AX0B 2BR6A 3IE2A 2FHXA 1QH5A 4F6HA 4Z6XA 4TZFA 1WRAA 3IEMA 2BMIA 2YNTB 4YSBA 3DHBA 5A87A 4D1VA 5HIPA 4NQ5A 3I11A 4AD9A 2AZ4A 2DKFA 3Q6VA 3PY5A 2CG3A 4GYQA 5AEBA 3T3OA 4D1UA 2XF4A 5AHOA 2A7MA 1X8HA 4HL1A 1JJTA 1QH3A 3DHCA 4PVOA 2GMNA 3S0ZA 2BGAA 5A23A 1KO2A 3L6NA 3ZNBA 1WW1A 2Q42A 5ACQA 4YSLA 4TZEA 5EV6A 2I7TA 1X8IA 5ACUA 1SMLA 2BTNA 2WYLA 3AJ3A 5LLDA 3IELA 4UWOB 5HISA 4FR7A 4UWRB 2NZEA 2OHJA 2OHHA 5IQKA 3X2XA 4PDXA 2AIOA 1YCFA 5B15A 3PG4A 5B3RA 2BFLA 2M5DA 3RPCA 3X2YA 2FM6A 1DXKA 4B87A 2Q9UA 2Y87A 1XTOA 3LVZA 3SBLA 2NZFA 2BG2A 3SPUA 3I14A 1A8TA 3AF5A 3T3NA 5LCFA 2ZZIA 4ZO3A 2FU7A 4H0DA 1YCGA 2BFZB 3VQZA 4O98A 4AV7A 4TYTA 4C1GA 2ZO4A 3IE0A 5K0WA 5K4MA 4EYBA 2P4ZA 3IOFA 1KR3A 5LCAA 3PY6A 1YCHA 2P1EA 4KEQA 4EYFA 1M2XA 5FQBA 2VW8A 2DOOA 2P97A 3T9MA 1DD6A 1XM8A 3I13A 1E5DA 2QJSA 3H3EA 2QINA 5A0TA 2WYMC 3IE1A 2QEDA 4C1FA 4C1CA 4XWWA 4AWZA 1KO3A 1BMCA 5AXRA 5AJLA 5HH6A 4ZO2A 4RL2A 4UWPB 2YNVB 3IOGA 2E7YA 5ACXA 2CFZA 5A0VA 3AF6A 2YHEA 1JT1A 3RKJA 1WUOA 4RAWA 5EVBA 3BK2A 5EW0A 1WUPA 2CG2A 5ACPA 4RBSA 2BG8B 4BP0A 3BC2A 1L9YA 5HIQA 4YSKA 2XR1A 2CFUA 1DDKA 3ESHA 5AHRA 1JJEA 4DIKA 5A5ZA 2FK6A 1X8GA 3MD7A 5ACWA 1ZNBA 3VPEA 2NYPA 2UYXA 3RKKA 2FHXB 4EFZA 2GKLA 2WRSA 4C09A 2YNTA 2YNUA 3I15A 5AYAA 5B1UA 4ZNBA 5EVKA 2YZ3A 2BG7A 3BK1A 5KIKA 4JO0A 4LE6A 5LS3A 4NQ4A 4UBQA 3F9OA 4C1DA 4C1EA 3I0VA 3IDZA 4UAMA 2YNWA 4NURA 3FAIA 4FEKA 3X2ZA 3KL7A 3FCZA 3SRXA 1BC2A 3SFPA 2CBNA 4D02A 2QDSA 3ZR9A 1Y44A 4RM5A 4WD6A 4AX1B 2QDTA 2R2DA 2Y8AA 2GFJA 4CHLA 4UWSB 5LE1A 2BC2A 4GCWA 4AXHA 2FU9A 3A4YA 2YCBA 3IEKA 4RAMA 5LCHA 5AIJA 1ZKPA 2HB9A 2WYMA 1VGNA 4Z60A 2BFKA 4Z67A 1K07A 4FSBA 4KEPA 3SD9A 5EHTA 4HKYA 5KILA 2GFKA 3X30A 5EV8A 4EY2A 3KNRA 4F6ZA 5ACTA 2ZNBA 2I7VA 3ZQ4A 1P9EA 4D1WA 2BIBA 4Z5ZA 4Z5YA 5FQCA 2Q0IA 3ZWFA 2FU8A 4EXYA 5ACSA 2H6AA 2M5CA 2BFZA 1VMEA 3R2UA 3SW3A 2NXAA 4P62A 5FQAA 5EWAA 5EH9A 1BVTA 1VJNA 5LM6A 3P2UA 5HIOA 4EYLA 4EXSA 4BZ3A 3G1PA 5HH5A 5AXOA 3DHAA 5LSCA 5HH4A 2FU6A 4TZBA 4J5HA 4NQ6A 4RL0A 4D1TA 1HLKA 3ADRA 4DILA 4HL2A 4XUKA 3WXCA 4J5FA 5EVDA 2I7XA 5ACRA 3TP9A 2YNVA 1ZTCA 4PVTA 2P18A 4ZEJA 2BG6A 4C1HA 5K4NA 5LMCA 5ACVA
chains in the Genus database with same CATH topology
5K4KA 2ZWRA 4UA4A 3KNSA 4Z7RA 3QH8A 4U4LA 1MQOA 2Q0JA 2BG8A 3JXPA 4GYUA 1A7TA 2GCUA 4NQ2A 2Y8BA 3DH8A 4AWYB 2OHIA 4XWTA 4TYFA 3BV6A 5DPXA 2WHGA 4TZ9A 4V0HA 4AX0B 2BR6A 3IE2A 2FHXA 1QH5A 4F6HA 4Z6XA 4TZFA 1WRAA 3IEMA 2BMIA 2YNTB 4YSBA 3DHBA 5A87A 4D1VA 5HIPA 4NQ5A 3I11A 4AD9A 2AZ4A 2DKFA 3Q6VA 3PY5A 4GYQA 5AEBA 3T3OA 4D1UA 2XF4A 5AHOA 2A7MA 1X8HA 4HL1A 1JJTA 1QH3A 3DHCA 4PVOA 2GMNA 3S0ZA 2BGAA 1KO2A 3L6NA 3ZNBA 1WW1A 2Q42A 5ACQA 4YSLA 4TZEA 5EV6A 2I7TA 1X8IA 5ACUA 1SMLA 2BTNA 2WYLA 3AJ3A 5LLDA 3IELA 4UWOB 5HISA 4FR7A 4UWRB 2NZEA 2OHJA 2OHHA 5IQKA 3X2XA 2AIOA 1YCFA 5B15A 3PG4A 5B3RA 2BFLA 2M5DA 3RPCA 3X2YA 2FM6A 1DXKA 4B87A 2Q9UA 2Y87A 1XTOA 3LVZA 3SBLA 2NZFA 2BG2A 3SPUA 3I14A 1A8TA 3AF5A 3T3NA 5LCFA 2ZZIA 4ZO3A 2FU7A 4H0DA 1YCGA 2BFZB 3VQZA 4O98A 4TYTA 4C1GA 2ZO4A 3IE0A 5K0WA 5K4MA 4EYBA 2P4ZA 3IOFA 1KR3A 5LCAA 3PY6A 1YCHA 2P1EA 4KEQA 4EYFA 1M2XA 5FQBA 2VW8A 2DOOA 2P97A 3T9MA 1DD6A 1XM8A 3I13A 1E5DA 2QJSA 3H3EA 2QINA 5A0TA 2WYMC 3IE1A 2QEDA 4C1FA 4C1CA 4XWWA 4AWZA 1KO3A 1BMCA 5AXRA 5HH6A 4ZO2A 4RL2A 4UWPB 2YNVB 3IOGA 2E7YA 5ACXA 5A0VA 3AF6A 1JT1A 3RKJA 1WUOA 4RAWA 5EVBA 3BK2A 5EW0A 1WUPA 5ACPA 4RBSA 2BG8B 4BP0A 3BC2A 1L9YA 5HIQA 4YSKA 2XR1A 1DDKA 3ESHA 5AHRA 1JJEA 4DIKA 5A5ZA 2FK6A 1X8GA 3MD7A 5ACWA 1ZNBA 3VPEA 2NYPA 2UYXA 3RKKA 2FHXB 4EFZA 2GKLA 2WRSA 4C09A 2YNTA 2YNUA 3I15A 5AYAA 5B1UA 4ZNBA 5EVKA 2YZ3A 2BG7A 3BK1A 5KIKA 4JO0A 4LE6A 5LS3A 4NQ4A 4UBQA 3F9OA 4C1DA 4C1EA 3I0VA 3IDZA 4UAMA 2YNWA 3FAIA 4FEKA 3X2ZA 3KL7A 3FCZA 3SRXA 1BC2A 3SFPA 2CBNA 4D02A 2QDSA 3ZR9A 1Y44A 4RM5A 4WD6A 4AX1B 2QDTA 2R2DA 2Y8AA 2GFJA 4CHLA 4UWSB 5LE1A 2BC2A 4GCWA 2FU9A 3A4YA 2YCBA 3IEKA 4RAMA 5LCHA 1ZKPA 2HB9A 2WYMA 1VGNA 4Z60A 2BFKA 4Z67A 1K07A 4FSBA 4KEPA 3SD9A 5EHTA 4HKYA 5KILA 2GFKA 3X30A 5EV8A 4EY2A 3KNRA 4F6ZA 5ACTA 2ZNBA 2I7VA 3ZQ4A 1P9EA 4D1WA 2BIBA 4Z5ZA 4Z5YA 5FQCA 2Q0IA 3ZWFA 2FU8A 4EXYA 5ACSA 2H6AA 2M5CA 2BFZA 1VMEA 3R2UA 3SW3A 2NXAA 4P62A 5FQAA 5EWAA 5EH9A 1BVTA 1VJNA 5LM6A 3P2UA 5HIOA 4EYLA 4EXSA 4BZ3A 3G1PA 5HH5A 5AXOA 3DHAA 5LSCA 5HH4A 2FU6A 4TZBA 4J5HA 4NQ6A 4RL0A 4D1TA 1HLKA 3ADRA 4DILA 4HL2A 4XUKA 3WXCA 4J5FA 5EVDA 2I7XA 5ACRA 3TP9A 2YNVA 1ZTCA 4PVTA 2P18A 4ZEJA 2BG6A 4C1HA 5K4NA 5LMCA 5ACVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5K4K A;  2ZWR A;  4UA4 A;  3KNS A;  4Z7R A;  3QH8 A;  4U4L A;  1MQO A;  2Q0J A;  2BG8 A;  3JXP A;  4GYU A;  1A7T A;  2GCU A;  4NQ2 A;  2Y8B A;  3DH8 A;  4AWY B;  2OHI A;  4XWT A;  4TYF A;  3BV6 A;  5DPX A;  2WHG A;  4TZ9 A;  4V0H A;  4AX0 B;  2BR6 A;  3IE2 A;  2FHX A;  1QH5 A;  4F6H A;  4Z6X A;  4TZF A;  1WRA A;  3IEM A;  2BMI A;  2YNT B;  4YSB A;  3DHB A;  5A87 A;  4D1V A;  5HIP A;  4NQ5 A;  3I11 A;  4AD9 A;  2AZ4 A;  2DKF A;  3Q6V A;  3PY5 A;  4GYQ A;  5AEB A;  3T3O A;  4D1U A;  2XF4 A;  5AHO A;  2A7M A;  1X8H A;  4HL1 A;  1JJT A;  1QH3 A;  3DHC A;  4PVO A;  2GMN A;  3S0Z A;  2BGA A;  1KO2 A;  3L6N A;  3ZNB A;  1WW1 A;  2Q42 A;  5ACQ A;  4YSL A;  4TZE A;  5EV6 A;  2I7T A;  1X8I A;  5ACU A;  1SML A;  2BTN A;  2WYL A;  3AJ3 A;  5LLD A;  3IEL A;  4UWO B;  5HIS A;  4FR7 A;  4UWR B;  2NZE A;  2OHJ A;  2OHH A;  5IQK A;  3X2X A;  2AIO A;  1YCF A;  5B15 A;  3PG4 A;  5B3R A;  2BFL A;  2M5D A;  3RPC A;  3X2Y A;  2FM6 A;  1DXK A;  4B87 A;  2Q9U A;  2Y87 A;  1XTO A;  3LVZ A;  3SBL A;  2NZF A;  2BG2 A;  3SPU A;  3I14 A;  1A8T A;  3AF5 A;  3T3N A;  5LCF A;  2ZZI A;  4ZO3 A;  2FU7 A;  4H0D A;  1YCG A;  2BFZ B;  3VQZ A;  4O98 A;  4TYT A;  4C1G A;  2ZO4 A;  3IE0 A;  5K0W A;  5K4M A;  4EYB A;  2P4Z A;  3IOF A;  1KR3 A;  5LCA A;  3PY6 A;  1YCH A;  2P1E A;  4KEQ A;  4EYF A;  1M2X A;  5FQB A;  2VW8 A;  2DOO A;  2P97 A;  3T9M A;  1DD6 A;  1XM8 A;  3I13 A;  1E5D A;  2QJS A;  3H3E A;  2QIN A;  5A0T A;  2WYM C;  3IE1 A;  2QED A;  4C1F A;  4C1C A;  4XWW A;  4AWZ A;  1KO3 A;  1BMC A;  5AXR A;  5HH6 A;  4ZO2 A;  4RL2 A;  4UWP B;  2YNV B;  3IOG A;  2E7Y A;  5ACX A;  5A0V A;  3AF6 A;  1JT1 A;  3RKJ A;  1WUO A;  4RAW A;  5EVB A;  3BK2 A;  5EW0 A;  1WUP A;  5ACP A;  4RBS A;  2BG8 B;  4BP0 A;  3BC2 A;  1L9Y A;  5HIQ A;  4YSK A;  2XR1 A;  1DDK A;  3ESH A;  5AHR A;  1JJE A;  4DIK A;  5A5Z A;  2FK6 A;  1X8G A;  3MD7 A;  5ACW A;  1ZNB A;  3VPE A;  2NYP A;  2UYX A;  3RKK A;  2FHX B;  4EFZ A;  2GKL A;  2WRS A;  4C09 A;  2YNT A;  2YNU A;  3I15 A;  5AYA A;  5B1U A;  4ZNB A;  5EVK A;  2YZ3 A;  2BG7 A;  3BK1 A;  5KIK A;  4JO0 A;  4LE6 A;  5LS3 A;  4NQ4 A;  4UBQ A;  3F9O A;  4C1D A;  4C1E A;  3I0V A;  3IDZ A;  4UAM A;  2YNW A;  3FAI A;  4FEK A;  3X2Z A;  3KL7 A;  3FCZ A;  3SRX A;  1BC2 A;  3SFP A;  2CBN A;  4D02 A;  2QDS A;  3ZR9 A;  1Y44 A;  4RM5 A;  4WD6 A;  4AX1 B;  2QDT A;  2R2D A;  2Y8A A;  2GFJ A;  4CHL A;  4UWS B;  5LE1 A;  2BC2 A;  4GCW A;  2FU9 A;  3A4Y A;  2YCB A;  3IEK A;  4RAM A;  5LCH A;  1ZKP A;  2HB9 A;  2WYM A;  1VGN A;  4Z60 A;  2BFK A;  4Z67 A;  1K07 A;  4FSB A;  4KEP A;  3SD9 A;  5EHT A;  4HKY A;  5KIL A;  2GFK A;  3X30 A;  5EV8 A;  4EY2 A;  3KNR A;  4F6Z A;  5ACT A;  2ZNB A;  2I7V A;  3ZQ4 A;  1P9E A;  4D1W A;  2BIB A;  4Z5Z A;  4Z5Y A;  5FQC A;  2Q0I A;  3ZWF A;  2FU8 A;  4EXY A;  5ACS A;  2H6A A;  2M5C A;  2BFZ A;  1VME A;  3R2U A;  3SW3 A;  2NXA A;  4P62 A;  5FQA A;  5EWA A;  5EH9 A;  1BVT A;  1VJN A;  5LM6 A;  3P2U A;  5HIO A;  4EYL A;  4EXS A;  4BZ3 A;  3G1P A;  5HH5 A;  5AXO A;  3DHA A;  5LSC A;  5HH4 A;  2FU6 A;  4TZB A;  4J5H A;  4NQ6 A;  4RL0 A;  4D1T A;  1HLK A;  3ADR A;  4DIL A;  4HL2 A;  4XUK A;  3WXC A;  4J5F A;  5EVD A;  2I7X A;  5ACR A;  3TP9 A;  2YNV A;  1ZTC A;  4PVT A;  2P18 A;  4ZEJ A;  2BG6 A;  4C1H A;  5K4N A;  5LMC A;  5ACV A; 
#chains in the Genus database with same CATH topology
 5K4K A;  2ZWR A;  4UA4 A;  3KNS A;  4Z7R A;  3QH8 A;  4U4L A;  1MQO A;  2Q0J A;  2BG8 A;  3JXP A;  4GYU A;  1A7T A;  2GCU A;  4NQ2 A;  2Y8B A;  3DH8 A;  4AWY B;  2OHI A;  4XWT A;  4TYF A;  3BV6 A;  5DPX A;  2WHG A;  4TZ9 A;  4V0H A;  4AX0 B;  2BR6 A;  3IE2 A;  2FHX A;  1QH5 A;  4F6H A;  4Z6X A;  4TZF A;  1WRA A;  3IEM A;  2BMI A;  2YNT B;  4YSB A;  3DHB A;  5A87 A;  4D1V A;  5HIP A;  4NQ5 A;  3I11 A;  4AD9 A;  2AZ4 A;  2DKF A;  3Q6V A;  3PY5 A;  2CG3 A;  4GYQ A;  5AEB A;  3T3O A;  4D1U A;  2XF4 A;  5AHO A;  2A7M A;  1X8H A;  4HL1 A;  1JJT A;  1QH3 A;  3DHC A;  4PVO A;  2GMN A;  3S0Z A;  2BGA A;  5A23 A;  1KO2 A;  3L6N A;  3ZNB A;  1WW1 A;  2Q42 A;  5ACQ A;  4YSL A;  4TZE A;  5EV6 A;  2I7T A;  1X8I A;  5ACU A;  1SML A;  2BTN A;  2WYL A;  3AJ3 A;  5LLD A;  3IEL A;  4UWO B;  5HIS A;  4FR7 A;  4UWR B;  2NZE A;  2OHJ A;  2OHH A;  5IQK A;  3X2X A;  4PDX A;  2AIO A;  1YCF A;  5B15 A;  3PG4 A;  5B3R A;  2BFL A;  2M5D A;  3RPC A;  3X2Y A;  2FM6 A;  1DXK A;  4B87 A;  2Q9U A;  2Y87 A;  1XTO A;  3LVZ A;  3SBL A;  2NZF A;  2BG2 A;  3SPU A;  3I14 A;  1A8T A;  3AF5 A;  3T3N A;  5LCF A;  2ZZI A;  4ZO3 A;  2FU7 A;  4H0D A;  1YCG A;  2BFZ B;  3VQZ A;  4O98 A;  4AV7 A;  4TYT A;  4C1G A;  2ZO4 A;  3IE0 A;  5K0W A;  5K4M A;  4EYB A;  2P4Z A;  3IOF A;  1KR3 A;  5LCA A;  3PY6 A;  1YCH A;  2P1E A;  4KEQ A;  4EYF A;  1M2X A;  5FQB A;  2VW8 A;  2DOO A;  2P97 A;  3T9M A;  1DD6 A;  1XM8 A;  3I13 A;  1E5D A;  2QJS A;  3H3E A;  2QIN A;  5A0T A;  2WYM C;  3IE1 A;  2QED A;  4C1F A;  4C1C A;  4XWW A;  4AWZ A;  1KO3 A;  1BMC A;  5AXR A;  5AJL A;  5HH6 A;  4ZO2 A;  4RL2 A;  4UWP B;  2YNV B;  3IOG A;  2E7Y A;  5ACX A;  2CFZ A;  5A0V A;  3AF6 A;  2YHE A;  1JT1 A;  3RKJ A;  1WUO A;  4RAW A;  5EVB A;  3BK2 A;  5EW0 A;  1WUP A;  2CG2 A;  5ACP A;  4RBS A;  2BG8 B;  4BP0 A;  3BC2 A;  1L9Y A;  5HIQ A;  4YSK A;  2XR1 A;  2CFU A;  1DDK A;  3ESH A;  5AHR A;  1JJE A;  4DIK A;  5A5Z A;  2FK6 A;  1X8G A;  3MD7 A;  5ACW A;  1ZNB A;  3VPE A;  2NYP A;  2UYX A;  3RKK A;  2FHX B;  4EFZ A;  2GKL A;  2WRS A;  4C09 A;  2YNT A;  2YNU A;  3I15 A;  5AYA A;  5B1U A;  4ZNB A;  5EVK A;  2YZ3 A;  2BG7 A;  3BK1 A;  5KIK A;  4JO0 A;  4LE6 A;  5LS3 A;  4NQ4 A;  4UBQ A;  3F9O A;  4C1D A;  4C1E A;  3I0V A;  3IDZ A;  4UAM A;  2YNW A;  4NUR A;  3FAI A;  4FEK A;  3X2Z A;  3KL7 A;  3FCZ A;  3SRX A;  1BC2 A;  3SFP A;  2CBN A;  4D02 A;  2QDS A;  3ZR9 A;  1Y44 A;  4RM5 A;  4WD6 A;  4AX1 B;  2QDT A;  2R2D A;  2Y8A A;  2GFJ A;  4CHL A;  4UWS B;  5LE1 A;  2BC2 A;  4GCW A;  4AXH A;  2FU9 A;  3A4Y A;  2YCB A;  3IEK A;  4RAM A;  5LCH A;  5AIJ A;  1ZKP A;  2HB9 A;  2WYM A;  1VGN A;  4Z60 A;  2BFK A;  4Z67 A;  1K07 A;  4FSB A;  4KEP A;  3SD9 A;  5EHT A;  4HKY A;  5KIL A;  2GFK A;  3X30 A;  5EV8 A;  4EY2 A;  3KNR A;  4F6Z A;  5ACT A;  2ZNB A;  2I7V A;  3ZQ4 A;  1P9E A;  4D1W A;  2BIB A;  4Z5Z A;  4Z5Y A;  5FQC A;  2Q0I A;  3ZWF A;  2FU8 A;  4EXY A;  5ACS A;  2H6A A;  2M5C A;  2BFZ A;  1VME A;  3R2U A;  3SW3 A;  2NXA A;  4P62 A;  5FQA A;  5EWA A;  5EH9 A;  1BVT A;  1VJN A;  5LM6 A;  3P2U A;  5HIO A;  4EYL A;  4EXS A;  4BZ3 A;  3G1P A;  5HH5 A;  5AXO A;  3DHA A;  5LSC A;  5HH4 A;  2FU6 A;  4TZB A;  4J5H A;  4NQ6 A;  4RL0 A;  4D1T A;  1HLK A;  3ADR A;  4DIL A;  4HL2 A;  4XUK A;  3WXC A;  4J5F A;  5EVD A;  2I7X A;  5ACR A;  3TP9 A;  2YNV A;  1ZTC A;  4PVT A;  2P18 A;  4ZEJ A;  2BG6 A;  4C1H A;  5K4N A;  5LMC A;  5ACV A; 
#chains in the Genus database with same CATH homology
 5K4K A;  2ZWR A;  4UA4 A;  3KNS A;  4Z7R A;  3QH8 A;  4U4L A;  1MQO A;  2Q0J A;  2BG8 A;  3JXP A;  4GYU A;  1A7T A;  2GCU A;  4NQ2 A;  2Y8B A;  3DH8 A;  4AWY B;  2OHI A;  4XWT A;  4TYF A;  3BV6 A;  5DPX A;  2WHG A;  4TZ9 A;  4V0H A;  4AX0 B;  2BR6 A;  3IE2 A;  2FHX A;  1QH5 A;  4F6H A;  4Z6X A;  4TZF A;  1WRA A;  3IEM A;  2BMI A;  2YNT B;  4YSB A;  3DHB A;  5A87 A;  4D1V A;  5HIP A;  4NQ5 A;  3I11 A;  4AD9 A;  2AZ4 A;  2DKF A;  3Q6V A;  3PY5 A;  4GYQ A;  5AEB A;  3T3O A;  4D1U A;  2XF4 A;  5AHO A;  2A7M A;  1X8H A;  4HL1 A;  1JJT A;  1QH3 A;  3DHC A;  4PVO A;  2GMN A;  3S0Z A;  2BGA A;  1KO2 A;  3L6N A;  3ZNB A;  1WW1 A;  2Q42 A;  5ACQ A;  4YSL A;  4TZE A;  5EV6 A;  2I7T A;  1X8I A;  5ACU A;  1SML A;  2BTN A;  2WYL A;  3AJ3 A;  5LLD A;  3IEL A;  4UWO B;  5HIS A;  4FR7 A;  4UWR B;  2NZE A;  2OHJ A;  2OHH A;  5IQK A;  3X2X A;  2AIO A;  1YCF A;  5B15 A;  3PG4 A;  5B3R A;  2BFL A;  2M5D A;  3RPC A;  3X2Y A;  2FM6 A;  1DXK A;  4B87 A;  2Q9U A;  2Y87 A;  1XTO A;  3LVZ A;  3SBL A;  2NZF A;  2BG2 A;  3SPU A;  3I14 A;  1A8T A;  3AF5 A;  3T3N A;  5LCF A;  2ZZI A;  4ZO3 A;  2FU7 A;  4H0D A;  1YCG A;  2BFZ B;  3VQZ A;  4O98 A;  4TYT A;  4C1G A;  2ZO4 A;  3IE0 A;  5K0W A;  5K4M A;  4EYB A;  2P4Z A;  3IOF A;  1KR3 A;  5LCA A;  3PY6 A;  1YCH A;  2P1E A;  4KEQ A;  4EYF A;  1M2X A;  5FQB A;  2VW8 A;  2DOO A;  2P97 A;  3T9M A;  1DD6 A;  1XM8 A;  3I13 A;  1E5D A;  2QJS A;  3H3E A;  2QIN A;  5A0T A;  2WYM C;  3IE1 A;  2QED A;  4C1F A;  4C1C A;  4XWW A;  4AWZ A;  1KO3 A;  1BMC A;  5AXR A;  5HH6 A;  4ZO2 A;  4RL2 A;  4UWP B;  2YNV B;  3IOG A;  2E7Y A;  5ACX A;  5A0V A;  3AF6 A;  1JT1 A;  3RKJ A;  1WUO A;  4RAW A;  5EVB A;  3BK2 A;  5EW0 A;  1WUP A;  5ACP A;  4RBS A;  2BG8 B;  4BP0 A;  3BC2 A;  1L9Y A;  5HIQ A;  4YSK A;  2XR1 A;  1DDK A;  3ESH A;  5AHR A;  1JJE A;  4DIK A;  5A5Z A;  2FK6 A;  1X8G A;  3MD7 A;  5ACW A;  1ZNB A;  3VPE A;  2NYP A;  2UYX A;  3RKK A;  2FHX B;  4EFZ A;  2GKL A;  2WRS A;  4C09 A;  2YNT A;  2YNU A;  3I15 A;  5AYA A;  5B1U A;  4ZNB A;  5EVK A;  2YZ3 A;  2BG7 A;  3BK1 A;  5KIK A;  4JO0 A;  4LE6 A;  5LS3 A;  4NQ4 A;  4UBQ A;  3F9O A;  4C1D A;  4C1E A;  3I0V A;  3IDZ A;  4UAM A;  2YNW A;  3FAI A;  4FEK A;  3X2Z A;  3KL7 A;  3FCZ A;  3SRX A;  1BC2 A;  3SFP A;  2CBN A;  4D02 A;  2QDS A;  3ZR9 A;  1Y44 A;  4RM5 A;  4WD6 A;  4AX1 B;  2QDT A;  2R2D A;  2Y8A A;  2GFJ A;  4CHL A;  4UWS B;  5LE1 A;  2BC2 A;  4GCW A;  2FU9 A;  3A4Y A;  2YCB A;  3IEK A;  4RAM A;  5LCH A;  1ZKP A;  2HB9 A;  2WYM A;  1VGN A;  4Z60 A;  2BFK A;  4Z67 A;  1K07 A;  4FSB A;  4KEP A;  3SD9 A;  5EHT A;  4HKY A;  5KIL A;  2GFK A;  3X30 A;  5EV8 A;  4EY2 A;  3KNR A;  4F6Z A;  5ACT A;  2ZNB A;  2I7V A;  3ZQ4 A;  1P9E A;  4D1W A;  2BIB A;  4Z5Z A;  4Z5Y A;  5FQC A;  2Q0I A;  3ZWF A;  2FU8 A;  4EXY A;  5ACS A;  2H6A A;  2M5C A;  2BFZ A;  1VME A;  3R2U A;  3SW3 A;  2NXA A;  4P62 A;  5FQA A;  5EWA A;  5EH9 A;  1BVT A;  1VJN A;  5LM6 A;  3P2U A;  5HIO A;  4EYL A;  4EXS A;  4BZ3 A;  3G1P A;  5HH5 A;  5AXO A;  3DHA A;  5LSC A;  5HH4 A;  2FU6 A;  4TZB A;  4J5H A;  4NQ6 A;  4RL0 A;  4D1T A;  1HLK A;  3ADR A;  4DIL A;  4HL2 A;  4XUK A;  3WXC A;  4J5F A;  5EVD A;  2I7X A;  5ACR A;  3TP9 A;  2YNV A;  1ZTC A;  4PVT A;  2P18 A;  4ZEJ A;  2BG6 A;  4C1H A;  5K4N A;  5LMC A;  5ACV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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