5ACUA

Vim-2-nat, discovery of novel inhibitor scaffolds against the metallo- beta-lactamase vim-2 by spr based fragment screening
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
231
structure length
230
Chain Sequence
GEYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of Novel Inhibitor Scaffolds Against the Metallo-Beta-Lactamase Vim-2 by Spr Based Fragment Screening
pubmed doi rcsb
source organism Pseudomonas aeruginosa
molecule tags Hydrolase
molecule keywords BETA-LACTAMASE
total genus 64
structure length 230
sequence length 231
ec nomenclature ec 3.5.2.6: Beta-lactamase.
pdb deposition date 2015-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5acuA00
2NZEA 4RAMA 5LCFA 3MD7A 3VPEA 2BR6A 4PVOA 2BG8A 3FCZA 5LCAA 5AYAA 4NQ6A 3AF5A 3IDZA 2ZWRA 2YNWA 3LVZA 4TYFA 2FU8A 4C1DA 2ZNBA 3X2YA 4D1UA 4AWZA 4JO0A 4U4LA 3IE2A 2GFJA 2P97A 4ZO3A 2FU7A 1SMLA 4CHLA 3PG4A 2OHIA 2VW8A 1ZNBA 5K4NA 5K0WA 2GCUA 2NYPA 3G1PA 5HH5A 4F6ZA 2P4ZA 3KNSA 2I7VA 4J5HA 1BVTA 1DDKA 4UWRB 4C1GA 4J5FA 2Y87A 4LE6A 2QINA 1WW1A 1E5DA 4DIKA 1HLKA 2XR1A 3DHAA 3ZQ4A 4AX1B 4AX0B 2YZ3A 3I11A 5HIQA 2HB9A 1A7TA 3DH8A 5EH9A 2H6AA 3IELA 4HKYA 3ESHA 3R2UA 3SRXA 5EWAA 2M5CA 4FSBA 5AXRA 4XWTA 3DHBA 3ZR9A 5ACPA 2XF4A 3FAIA 4TYTA 2Q0IA 2FM6A 4HL2A 3S0ZA 2M5DA 4TZEA 2OHHA 5ACTA 4UBQA 2YNTA 5AHOA 3RKKA 4EYLA 3JXPA 1K07A 1XTOA 4ZO2A 3BK1A 4AD9A 4C09A 3IEKA 3IOFA 1JT1A 3IEMA 3SFPA 4UWPB 1KR3A 1WRAA 3SBLA 5ACSA 4UWSB 3BV6A 4B87A 5KILA 2E7YA 1QH3A 2AIOA 4RL2A 2FK6A 1Y44A 1JJEA 2YCBA 3TP9A 3IE1A 5ACUA 2NXAA 5HISA 2Q42A 2BFLA 5HIOA 3X2XA 5EV8A 4TZ9A 3X2ZA 3H3EA 4XUKA 5EW0A 5LM6A 4P62A 5AHRA 5LLDA 3I0VA 4EYFA 5LCHA 4Z6XA 3BK2A 3P2UA 4RM5A 5AEBA 3ZNBA 1A8TA 2A7MA 5EHTA 5ACRA 4EY2A 5LE1A 4EXYA 5FQCA 3T3NA 4KEPA 2WYLA 2BG8B 4UA4A 1BC2A 4GCWA 3VQZA 3ADRA 1VJNA 4UAMA 5FQAA 4F6HA 4AWYB 1M2XA 3ZWFA 5ACVA 5EV6A 2Y8BA 2BFKA 4Z5YA 2WHGA 3T9MA 4YSLA 1DD6A 4PVTA 5AXOA 3SPUA 4H0DA 3SW3A 2YNTB 5HIPA 1YCFA 2QDTA 2ZZIA 2FU9A 4D1TA 1DXKA 5K4KA 2P18A 5EVDA 4ZEJA 1VGNA 5ACWA 1BMCA 2FU6A 4YSKA 3AJ3A 4BP0A 1VMEA 2YNVB 1WUPA 3L6NA 1ZTCA 5EVBA 5A87A 2I7XA 5LMCA 4EFZA 4NQ2A 3X30A 3I14A 5IQKA 5K4MA 2FHXB 3IE0A 5B15A 4V0HA 3DHCA 5LSCA 3T3OA 2BG7A 4EYBA 3IOGA 4WD6A 2WYMC 5A5ZA 4C1EA 3RPCA 3WXCA 4EXSA 2FHXA 3RKJA 3KNRA 3PY6A 5ACQA 4HL1A 4TZBA 3BC2A 2Y8AA 3AF6A 3QH8A 4C1CA 4UWOB 1JJTA 4Z67A 2YNVA 2NZFA 2BFZA 2GKLA 2QEDA 1YCHA 3SD9A 5B1UA 4RAWA 2BC2A 1KO3A 2DKFA 2GMNA 2DOOA 2BFZB 4DILA 4ZNBA 1X8IA 4Z5ZA 2BTNA 2BG6A 3KL7A 5KIKA 2BGAA 4NQ5A 1YCGA 5EVKA 5A0TA 1P9EA 1X8GA 2WRSA 3Q6VA 2R2DA 2Q9UA 3I13A 3PY5A 3F9OA 2QDSA 4KEQA 4XWWA 2WYMA 5B3RA 1ZKPA 1MQOA 4Z60A 2BG2A 2AZ4A 4FEKA 5LS3A 4FR7A 4D1WA 2OHJA 1X8HA 2YNUA 2QJSA 1WUOA 4NQ4A 2BMIA 2P1EA 4BZ3A 2CBNA 4GYQA 4YSBA 5DPXA 4GYUA 3I15A 2BIBA 2I7TA 3A4YA 1XM8A 1KO2A 5HH4A 4C1FA 1QH5A 2Q0JA 4Z7RA 1L9YA 4D02A 4RBSA 2ZO4A 4RL0A 4D1VA 2UYXA 4O98A 5FQBA 4TZFA 4C1HA 5ACXA 2GFKA 5HH6A 5A0VA
chains in the Genus database with same CATH superfamily
2NZEA 4RAMA 5LCFA 3MD7A 3VPEA 2BR6A 4PVOA 2BG8A 3FCZA 5LCAA 5AYAA 4NQ6A 3AF5A 3IDZA 2ZWRA 2YNWA 3LVZA 4TYFA 2FU8A 4C1DA 2ZNBA 3X2YA 4D1UA 4AWZA 4JO0A 4U4LA 2CG3A 3IE2A 2GFJA 2P97A 4ZO3A 2FU7A 1SMLA 4CHLA 3PG4A 2OHIA 2VW8A 1ZNBA 5K4NA 5K0WA 2GCUA 2NYPA 3G1PA 5HH5A 4F6ZA 2P4ZA 3KNSA 2I7VA 4J5HA 1BVTA 1DDKA 4UWRB 4C1GA 4J5FA 2Y87A 4LE6A 2QINA 1WW1A 1E5DA 4DIKA 1HLKA 2XR1A 3DHAA 3ZQ4A 4AX1B 4AX0B 2YZ3A 3I11A 5HIQA 2HB9A 1A7TA 3DH8A 5EH9A 2H6AA 3IELA 4HKYA 3ESHA 3R2UA 3SRXA 5EWAA 2M5CA 4FSBA 5AXRA 4XWTA 3DHBA 3ZR9A 5ACPA 2XF4A 3FAIA 4TYTA 2Q0IA 2FM6A 4HL2A 3S0ZA 2M5DA 4TZEA 2OHHA 5ACTA 4UBQA 2YNTA 4AXHA 5AHOA 3RKKA 4EYLA 3JXPA 1K07A 1XTOA 4AV7A 4ZO2A 3BK1A 4AD9A 4C09A 3IEKA 3IOFA 1JT1A 3IEMA 3SFPA 4UWPB 1KR3A 1WRAA 3SBLA 5ACSA 4UWSB 3BV6A 2CFZA 4B87A 5KILA 2E7YA 1QH3A 2AIOA 4RL2A 2FK6A 1Y44A 1JJEA 2YCBA 3TP9A 3IE1A 5ACUA 2NXAA 5HISA 2Q42A 2BFLA 5HIOA 3X2XA 5EV8A 4TZ9A 3X2ZA 3H3EA 4XUKA 5EW0A 5LM6A 4P62A 5AHRA 5LLDA 3I0VA 4EYFA 5LCHA 4Z6XA 3BK2A 3P2UA 4RM5A 5AEBA 3ZNBA 1A8TA 2A7MA 5EHTA 5ACRA 4EY2A 2CFUA 5AJLA 5LE1A 4EXYA 5FQCA 3T3NA 4KEPA 2WYLA 2BG8B 4UA4A 1BC2A 5A23A 4GCWA 3VQZA 3ADRA 1VJNA 4UAMA 5FQAA 4F6HA 4AWYB 1M2XA 3ZWFA 5ACVA 5EV6A 2Y8BA 2BFKA 4Z5YA 2WHGA 3T9MA 4YSLA 1DD6A 4PVTA 5AXOA 3SPUA 4H0DA 3SW3A 2YNTB 5HIPA 1YCFA 2QDTA 2ZZIA 2FU9A 4D1TA 1DXKA 5K4KA 2P18A 5EVDA 4ZEJA 1VGNA 5ACWA 1BMCA 2FU6A 4YSKA 3AJ3A 4BP0A 1VMEA 2YNVB 1WUPA 3L6NA 1ZTCA 5EVBA 5A87A 2I7XA 5LMCA 4EFZA 4NQ2A 3X30A 3I14A 5AIJA 5IQKA 5K4MA 2FHXB 3IE0A 5B15A 4V0HA 3DHCA 5LSCA 3T3OA 2BG7A 4EYBA 3IOGA 4WD6A 2WYMC 5A5ZA 4C1EA 4NURA 3RPCA 3WXCA 4EXSA 2FHXA 3RKJA 3KNRA 3PY6A 5ACQA 4HL1A 4TZBA 3BC2A 2Y8AA 3AF6A 3QH8A 4C1CA 4UWOB 1JJTA 4Z67A 2YNVA 2NZFA 2BFZA 2GKLA 2QEDA 1YCHA 3SD9A 5B1UA 4RAWA 2BC2A 1KO3A 2DKFA 2GMNA 2DOOA 2BFZB 4DILA 4ZNBA 1X8IA 4Z5ZA 2BTNA 2BG6A 3KL7A 5KIKA 2BGAA 4NQ5A 1YCGA 5EVKA 5A0TA 1P9EA 1X8GA 2WRSA 2CG2A 3Q6VA 2R2DA 2Q9UA 3I13A 3PY5A 3F9OA 2QDSA 4KEQA 4XWWA 2WYMA 5B3RA 1ZKPA 1MQOA 4Z60A 2BG2A 2AZ4A 4FEKA 5LS3A 4FR7A 4D1WA 2OHJA 1X8HA 2YNUA 2QJSA 1WUOA 4NQ4A 2BMIA 2P1EA 4BZ3A 2CBNA 4GYQA 4YSBA 5DPXA 4GYUA 3I15A 2BIBA 2I7TA 3A4YA 1XM8A 1KO2A 5HH4A 4PDXA 4C1FA 1QH5A 2Q0JA 4Z7RA 1L9YA 4D02A 4RBSA 2ZO4A 4RL0A 4D1VA 2UYXA 4O98A 5FQBA 4TZFA 4C1HA 5ACXA 2GFKA 2YHEA 5HH6A 5A0VA
chains in the Genus database with same CATH topology
2NZEA 4RAMA 5LCFA 3MD7A 3VPEA 2BR6A 4PVOA 2BG8A 3FCZA 5LCAA 5AYAA 4NQ6A 3AF5A 3IDZA 2ZWRA 2YNWA 3LVZA 4TYFA 2FU8A 4C1DA 2ZNBA 3X2YA 4D1UA 4AWZA 4JO0A 4U4LA 3IE2A 2GFJA 2P97A 4ZO3A 2FU7A 1SMLA 4CHLA 3PG4A 2OHIA 2VW8A 1ZNBA 5K4NA 5K0WA 2GCUA 2NYPA 3G1PA 5HH5A 4F6ZA 2P4ZA 3KNSA 2I7VA 4J5HA 1BVTA 1DDKA 4UWRB 4C1GA 4J5FA 2Y87A 4LE6A 2QINA 1WW1A 1E5DA 4DIKA 1HLKA 2XR1A 3DHAA 3ZQ4A 4AX1B 4AX0B 2YZ3A 3I11A 5HIQA 2HB9A 1A7TA 3DH8A 5EH9A 2H6AA 3IELA 4HKYA 3ESHA 3R2UA 3SRXA 5EWAA 2M5CA 4FSBA 5AXRA 4XWTA 3DHBA 3ZR9A 5ACPA 2XF4A 3FAIA 4TYTA 2Q0IA 2FM6A 4HL2A 3S0ZA 2M5DA 4TZEA 2OHHA 5ACTA 4UBQA 2YNTA 5AHOA 3RKKA 4EYLA 3JXPA 1K07A 1XTOA 4ZO2A 3BK1A 4AD9A 4C09A 3IEKA 3IOFA 1JT1A 3IEMA 3SFPA 4UWPB 1KR3A 1WRAA 3SBLA 5ACSA 4UWSB 3BV6A 4B87A 5KILA 2E7YA 1QH3A 2AIOA 4RL2A 2FK6A 1Y44A 1JJEA 2YCBA 3TP9A 3IE1A 5ACUA 2NXAA 5HISA 2Q42A 2BFLA 5HIOA 3X2XA 5EV8A 4TZ9A 3X2ZA 3H3EA 4XUKA 5EW0A 5LM6A 4P62A 5AHRA 5LLDA 3I0VA 4EYFA 5LCHA 4Z6XA 3BK2A 3P2UA 4RM5A 5AEBA 3ZNBA 1A8TA 2A7MA 5EHTA 5ACRA 4EY2A 5LE1A 4EXYA 5FQCA 3T3NA 4KEPA 2WYLA 2BG8B 4UA4A 1BC2A 4GCWA 3VQZA 3ADRA 1VJNA 4UAMA 5FQAA 4F6HA 4AWYB 1M2XA 3ZWFA 5ACVA 5EV6A 2Y8BA 2BFKA 4Z5YA 2WHGA 3T9MA 4YSLA 1DD6A 4PVTA 5AXOA 3SPUA 4H0DA 3SW3A 2YNTB 5HIPA 1YCFA 2QDTA 2ZZIA 2FU9A 4D1TA 1DXKA 5K4KA 2P18A 5EVDA 4ZEJA 1VGNA 5ACWA 1BMCA 2FU6A 4YSKA 3AJ3A 4BP0A 1VMEA 2YNVB 1WUPA 3L6NA 1ZTCA 5EVBA 5A87A 2I7XA 5LMCA 4EFZA 4NQ2A 3X30A 3I14A 5IQKA 5K4MA 2FHXB 3IE0A 5B15A 4V0HA 3DHCA 5LSCA 3T3OA 2BG7A 4EYBA 3IOGA 4WD6A 2WYMC 5A5ZA 4C1EA 3RPCA 3WXCA 4EXSA 2FHXA 3RKJA 3KNRA 3PY6A 5ACQA 4HL1A 4TZBA 3BC2A 2Y8AA 3AF6A 3QH8A 4C1CA 4UWOB 1JJTA 4Z67A 2YNVA 2NZFA 2BFZA 2GKLA 2QEDA 1YCHA 3SD9A 5B1UA 4RAWA 2BC2A 1KO3A 2DKFA 2GMNA 2DOOA 2BFZB 4DILA 4ZNBA 1X8IA 4Z5ZA 2BTNA 2BG6A 3KL7A 5KIKA 2BGAA 4NQ5A 1YCGA 5EVKA 5A0TA 1P9EA 1X8GA 2WRSA 3Q6VA 2R2DA 2Q9UA 3I13A 3PY5A 3F9OA 2QDSA 4KEQA 4XWWA 2WYMA 5B3RA 1ZKPA 1MQOA 4Z60A 2BG2A 2AZ4A 4FEKA 5LS3A 4FR7A 4D1WA 2OHJA 1X8HA 2YNUA 2QJSA 1WUOA 4NQ4A 2BMIA 2P1EA 4BZ3A 2CBNA 4GYQA 4YSBA 5DPXA 4GYUA 3I15A 2BIBA 2I7TA 3A4YA 1XM8A 1KO2A 5HH4A 4C1FA 1QH5A 2Q0JA 4Z7RA 1L9YA 4D02A 4RBSA 2ZO4A 4RL0A 4D1VA 2UYXA 4O98A 5FQBA 4TZFA 4C1HA 5ACXA 2GFKA 5HH6A 5A0VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NZE A;  4RAM A;  5LCF A;  3MD7 A;  3VPE A;  2BR6 A;  4PVO A;  2BG8 A;  3FCZ A;  5LCA A;  5AYA A;  4NQ6 A;  3AF5 A;  3IDZ A;  2ZWR A;  2YNW A;  3LVZ A;  4TYF A;  2FU8 A;  4C1D A;  2ZNB A;  3X2Y A;  4D1U A;  4AWZ A;  4JO0 A;  4U4L A;  3IE2 A;  2GFJ A;  2P97 A;  4ZO3 A;  2FU7 A;  1SML A;  4CHL A;  3PG4 A;  2OHI A;  2VW8 A;  1ZNB A;  5K4N A;  5K0W A;  2GCU A;  2NYP A;  3G1P A;  5HH5 A;  4F6Z A;  2P4Z A;  3KNS A;  2I7V A;  4J5H A;  1BVT A;  1DDK A;  4UWR B;  4C1G A;  4J5F A;  2Y87 A;  4LE6 A;  2QIN A;  1WW1 A;  1E5D A;  4DIK A;  1HLK A;  2XR1 A;  3DHA A;  3ZQ4 A;  4AX1 B;  4AX0 B;  2YZ3 A;  3I11 A;  5HIQ A;  2HB9 A;  1A7T A;  3DH8 A;  5EH9 A;  2H6A A;  3IEL A;  4HKY A;  3ESH A;  3R2U A;  3SRX A;  5EWA A;  2M5C A;  4FSB A;  5AXR A;  4XWT A;  3DHB A;  3ZR9 A;  5ACP A;  2XF4 A;  3FAI A;  4TYT A;  2Q0I A;  2FM6 A;  4HL2 A;  3S0Z A;  2M5D A;  4TZE A;  2OHH A;  5ACT A;  4UBQ A;  2YNT A;  5AHO A;  3RKK A;  4EYL A;  3JXP A;  1K07 A;  1XTO A;  4ZO2 A;  3BK1 A;  4AD9 A;  4C09 A;  3IEK A;  3IOF A;  1JT1 A;  3IEM A;  3SFP A;  4UWP B;  1KR3 A;  1WRA A;  3SBL A;  5ACS A;  4UWS B;  3BV6 A;  4B87 A;  5KIL A;  2E7Y A;  1QH3 A;  2AIO A;  4RL2 A;  2FK6 A;  1Y44 A;  1JJE A;  2YCB A;  3TP9 A;  3IE1 A;  5ACU A;  2NXA A;  5HIS A;  2Q42 A;  2BFL A;  5HIO A;  3X2X A;  5EV8 A;  4TZ9 A;  3X2Z A;  3H3E A;  4XUK A;  5EW0 A;  5LM6 A;  4P62 A;  5AHR A;  5LLD A;  3I0V A;  4EYF A;  5LCH A;  4Z6X A;  3BK2 A;  3P2U A;  4RM5 A;  5AEB A;  3ZNB A;  1A8T A;  2A7M A;  5EHT A;  5ACR A;  4EY2 A;  5LE1 A;  4EXY A;  5FQC A;  3T3N A;  4KEP A;  2WYL A;  2BG8 B;  4UA4 A;  1BC2 A;  4GCW A;  3VQZ A;  3ADR A;  1VJN A;  4UAM A;  5FQA A;  4F6H A;  4AWY B;  1M2X A;  3ZWF A;  5ACV A;  5EV6 A;  2Y8B A;  2BFK A;  4Z5Y A;  2WHG A;  3T9M A;  4YSL A;  1DD6 A;  4PVT A;  5AXO A;  3SPU A;  4H0D A;  3SW3 A;  2YNT B;  5HIP A;  1YCF A;  2QDT A;  2ZZI A;  2FU9 A;  4D1T A;  1DXK A;  5K4K A;  2P18 A;  5EVD A;  4ZEJ A;  1VGN A;  5ACW A;  1BMC A;  2FU6 A;  4YSK A;  3AJ3 A;  4BP0 A;  1VME A;  2YNV B;  1WUP A;  3L6N A;  1ZTC A;  5EVB A;  5A87 A;  2I7X A;  5LMC A;  4EFZ A;  4NQ2 A;  3X30 A;  3I14 A;  5IQK A;  5K4M A;  2FHX B;  3IE0 A;  5B15 A;  4V0H A;  3DHC A;  5LSC A;  3T3O A;  2BG7 A;  4EYB A;  3IOG A;  4WD6 A;  2WYM C;  5A5Z A;  4C1E A;  3RPC A;  3WXC A;  4EXS A;  2FHX A;  3RKJ A;  3KNR A;  3PY6 A;  5ACQ A;  4HL1 A;  4TZB A;  3BC2 A;  2Y8A A;  3AF6 A;  3QH8 A;  4C1C A;  4UWO B;  1JJT A;  4Z67 A;  2YNV A;  2NZF A;  2BFZ A;  2GKL A;  2QED A;  1YCH A;  3SD9 A;  5B1U A;  4RAW A;  2BC2 A;  1KO3 A;  2DKF A;  2GMN A;  2DOO A;  2BFZ B;  4DIL A;  4ZNB A;  1X8I A;  4Z5Z A;  2BTN A;  2BG6 A;  3KL7 A;  5KIK A;  2BGA A;  4NQ5 A;  1YCG A;  5EVK A;  5A0T A;  1P9E A;  1X8G A;  2WRS A;  3Q6V A;  2R2D A;  2Q9U A;  3I13 A;  3PY5 A;  3F9O A;  2QDS A;  4KEQ A;  4XWW A;  2WYM A;  5B3R A;  1ZKP A;  1MQO A;  4Z60 A;  2BG2 A;  2AZ4 A;  4FEK A;  5LS3 A;  4FR7 A;  4D1W A;  2OHJ A;  1X8H A;  2YNU A;  2QJS A;  1WUO A;  4NQ4 A;  2BMI A;  2P1E A;  4BZ3 A;  2CBN A;  4GYQ A;  4YSB A;  5DPX A;  4GYU A;  3I15 A;  2BIB A;  2I7T A;  3A4Y A;  1XM8 A;  1KO2 A;  5HH4 A;  4C1F A;  1QH5 A;  2Q0J A;  4Z7R A;  1L9Y A;  4D02 A;  4RBS A;  2ZO4 A;  4RL0 A;  4D1V A;  2UYX A;  4O98 A;  5FQB A;  4TZF A;  4C1H A;  5ACX A;  2GFK A;  5HH6 A;  5A0V A; 
#chains in the Genus database with same CATH topology
 2NZE A;  4RAM A;  5LCF A;  3MD7 A;  3VPE A;  2BR6 A;  4PVO A;  2BG8 A;  3FCZ A;  5LCA A;  5AYA A;  4NQ6 A;  3AF5 A;  3IDZ A;  2ZWR A;  2YNW A;  3LVZ A;  4TYF A;  2FU8 A;  4C1D A;  2ZNB A;  3X2Y A;  4D1U A;  4AWZ A;  4JO0 A;  4U4L A;  2CG3 A;  3IE2 A;  2GFJ A;  2P97 A;  4ZO3 A;  2FU7 A;  1SML A;  4CHL A;  3PG4 A;  2OHI A;  2VW8 A;  1ZNB A;  5K4N A;  5K0W A;  2GCU A;  2NYP A;  3G1P A;  5HH5 A;  4F6Z A;  2P4Z A;  3KNS A;  2I7V A;  4J5H A;  1BVT A;  1DDK A;  4UWR B;  4C1G A;  4J5F A;  2Y87 A;  4LE6 A;  2QIN A;  1WW1 A;  1E5D A;  4DIK A;  1HLK A;  2XR1 A;  3DHA A;  3ZQ4 A;  4AX1 B;  4AX0 B;  2YZ3 A;  3I11 A;  5HIQ A;  2HB9 A;  1A7T A;  3DH8 A;  5EH9 A;  2H6A A;  3IEL A;  4HKY A;  3ESH A;  3R2U A;  3SRX A;  5EWA A;  2M5C A;  4FSB A;  5AXR A;  4XWT A;  3DHB A;  3ZR9 A;  5ACP A;  2XF4 A;  3FAI A;  4TYT A;  2Q0I A;  2FM6 A;  4HL2 A;  3S0Z A;  2M5D A;  4TZE A;  2OHH A;  5ACT A;  4UBQ A;  2YNT A;  4AXH A;  5AHO A;  3RKK A;  4EYL A;  3JXP A;  1K07 A;  1XTO A;  4AV7 A;  4ZO2 A;  3BK1 A;  4AD9 A;  4C09 A;  3IEK A;  3IOF A;  1JT1 A;  3IEM A;  3SFP A;  4UWP B;  1KR3 A;  1WRA A;  3SBL A;  5ACS A;  4UWS B;  3BV6 A;  2CFZ A;  4B87 A;  5KIL A;  2E7Y A;  1QH3 A;  2AIO A;  4RL2 A;  2FK6 A;  1Y44 A;  1JJE A;  2YCB A;  3TP9 A;  3IE1 A;  5ACU A;  2NXA A;  5HIS A;  2Q42 A;  2BFL A;  5HIO A;  3X2X A;  5EV8 A;  4TZ9 A;  3X2Z A;  3H3E A;  4XUK A;  5EW0 A;  5LM6 A;  4P62 A;  5AHR A;  5LLD A;  3I0V A;  4EYF A;  5LCH A;  4Z6X A;  3BK2 A;  3P2U A;  4RM5 A;  5AEB A;  3ZNB A;  1A8T A;  2A7M A;  5EHT A;  5ACR A;  4EY2 A;  2CFU A;  5AJL A;  5LE1 A;  4EXY A;  5FQC A;  3T3N A;  4KEP A;  2WYL A;  2BG8 B;  4UA4 A;  1BC2 A;  5A23 A;  4GCW A;  3VQZ A;  3ADR A;  1VJN A;  4UAM A;  5FQA A;  4F6H A;  4AWY B;  1M2X A;  3ZWF A;  5ACV A;  5EV6 A;  2Y8B A;  2BFK A;  4Z5Y A;  2WHG A;  3T9M A;  4YSL A;  1DD6 A;  4PVT A;  5AXO A;  3SPU A;  4H0D A;  3SW3 A;  2YNT B;  5HIP A;  1YCF A;  2QDT A;  2ZZI A;  2FU9 A;  4D1T A;  1DXK A;  5K4K A;  2P18 A;  5EVD A;  4ZEJ A;  1VGN A;  5ACW A;  1BMC A;  2FU6 A;  4YSK A;  3AJ3 A;  4BP0 A;  1VME A;  2YNV B;  1WUP A;  3L6N A;  1ZTC A;  5EVB A;  5A87 A;  2I7X A;  5LMC A;  4EFZ A;  4NQ2 A;  3X30 A;  3I14 A;  5AIJ A;  5IQK A;  5K4M A;  2FHX B;  3IE0 A;  5B15 A;  4V0H A;  3DHC A;  5LSC A;  3T3O A;  2BG7 A;  4EYB A;  3IOG A;  4WD6 A;  2WYM C;  5A5Z A;  4C1E A;  4NUR A;  3RPC A;  3WXC A;  4EXS A;  2FHX A;  3RKJ A;  3KNR A;  3PY6 A;  5ACQ A;  4HL1 A;  4TZB A;  3BC2 A;  2Y8A A;  3AF6 A;  3QH8 A;  4C1C A;  4UWO B;  1JJT A;  4Z67 A;  2YNV A;  2NZF A;  2BFZ A;  2GKL A;  2QED A;  1YCH A;  3SD9 A;  5B1U A;  4RAW A;  2BC2 A;  1KO3 A;  2DKF A;  2GMN A;  2DOO A;  2BFZ B;  4DIL A;  4ZNB A;  1X8I A;  4Z5Z A;  2BTN A;  2BG6 A;  3KL7 A;  5KIK A;  2BGA A;  4NQ5 A;  1YCG A;  5EVK A;  5A0T A;  1P9E A;  1X8G A;  2WRS A;  2CG2 A;  3Q6V A;  2R2D A;  2Q9U A;  3I13 A;  3PY5 A;  3F9O A;  2QDS A;  4KEQ A;  4XWW A;  2WYM A;  5B3R A;  1ZKP A;  1MQO A;  4Z60 A;  2BG2 A;  2AZ4 A;  4FEK A;  5LS3 A;  4FR7 A;  4D1W A;  2OHJ A;  1X8H A;  2YNU A;  2QJS A;  1WUO A;  4NQ4 A;  2BMI A;  2P1E A;  4BZ3 A;  2CBN A;  4GYQ A;  4YSB A;  5DPX A;  4GYU A;  3I15 A;  2BIB A;  2I7T A;  3A4Y A;  1XM8 A;  1KO2 A;  5HH4 A;  4PDX A;  4C1F A;  1QH5 A;  2Q0J A;  4Z7R A;  1L9Y A;  4D02 A;  4RBS A;  2ZO4 A;  4RL0 A;  4D1V A;  2UYX A;  4O98 A;  5FQB A;  4TZF A;  4C1H A;  5ACX A;  2GFK A;  2YHE A;  5HH6 A;  5A0V A; 
#chains in the Genus database with same CATH homology
 2NZE A;  4RAM A;  5LCF A;  3MD7 A;  3VPE A;  2BR6 A;  4PVO A;  2BG8 A;  3FCZ A;  5LCA A;  5AYA A;  4NQ6 A;  3AF5 A;  3IDZ A;  2ZWR A;  2YNW A;  3LVZ A;  4TYF A;  2FU8 A;  4C1D A;  2ZNB A;  3X2Y A;  4D1U A;  4AWZ A;  4JO0 A;  4U4L A;  3IE2 A;  2GFJ A;  2P97 A;  4ZO3 A;  2FU7 A;  1SML A;  4CHL A;  3PG4 A;  2OHI A;  2VW8 A;  1ZNB A;  5K4N A;  5K0W A;  2GCU A;  2NYP A;  3G1P A;  5HH5 A;  4F6Z A;  2P4Z A;  3KNS A;  2I7V A;  4J5H A;  1BVT A;  1DDK A;  4UWR B;  4C1G A;  4J5F A;  2Y87 A;  4LE6 A;  2QIN A;  1WW1 A;  1E5D A;  4DIK A;  1HLK A;  2XR1 A;  3DHA A;  3ZQ4 A;  4AX1 B;  4AX0 B;  2YZ3 A;  3I11 A;  5HIQ A;  2HB9 A;  1A7T A;  3DH8 A;  5EH9 A;  2H6A A;  3IEL A;  4HKY A;  3ESH A;  3R2U A;  3SRX A;  5EWA A;  2M5C A;  4FSB A;  5AXR A;  4XWT A;  3DHB A;  3ZR9 A;  5ACP A;  2XF4 A;  3FAI A;  4TYT A;  2Q0I A;  2FM6 A;  4HL2 A;  3S0Z A;  2M5D A;  4TZE A;  2OHH A;  5ACT A;  4UBQ A;  2YNT A;  5AHO A;  3RKK A;  4EYL A;  3JXP A;  1K07 A;  1XTO A;  4ZO2 A;  3BK1 A;  4AD9 A;  4C09 A;  3IEK A;  3IOF A;  1JT1 A;  3IEM A;  3SFP A;  4UWP B;  1KR3 A;  1WRA A;  3SBL A;  5ACS A;  4UWS B;  3BV6 A;  4B87 A;  5KIL A;  2E7Y A;  1QH3 A;  2AIO A;  4RL2 A;  2FK6 A;  1Y44 A;  1JJE A;  2YCB A;  3TP9 A;  3IE1 A;  5ACU A;  2NXA A;  5HIS A;  2Q42 A;  2BFL A;  5HIO A;  3X2X A;  5EV8 A;  4TZ9 A;  3X2Z A;  3H3E A;  4XUK A;  5EW0 A;  5LM6 A;  4P62 A;  5AHR A;  5LLD A;  3I0V A;  4EYF A;  5LCH A;  4Z6X A;  3BK2 A;  3P2U A;  4RM5 A;  5AEB A;  3ZNB A;  1A8T A;  2A7M A;  5EHT A;  5ACR A;  4EY2 A;  5LE1 A;  4EXY A;  5FQC A;  3T3N A;  4KEP A;  2WYL A;  2BG8 B;  4UA4 A;  1BC2 A;  4GCW A;  3VQZ A;  3ADR A;  1VJN A;  4UAM A;  5FQA A;  4F6H A;  4AWY B;  1M2X A;  3ZWF A;  5ACV A;  5EV6 A;  2Y8B A;  2BFK A;  4Z5Y A;  2WHG A;  3T9M A;  4YSL A;  1DD6 A;  4PVT A;  5AXO A;  3SPU A;  4H0D A;  3SW3 A;  2YNT B;  5HIP A;  1YCF A;  2QDT A;  2ZZI A;  2FU9 A;  4D1T A;  1DXK A;  5K4K A;  2P18 A;  5EVD A;  4ZEJ A;  1VGN A;  5ACW A;  1BMC A;  2FU6 A;  4YSK A;  3AJ3 A;  4BP0 A;  1VME A;  2YNV B;  1WUP A;  3L6N A;  1ZTC A;  5EVB A;  5A87 A;  2I7X A;  5LMC A;  4EFZ A;  4NQ2 A;  3X30 A;  3I14 A;  5IQK A;  5K4M A;  2FHX B;  3IE0 A;  5B15 A;  4V0H A;  3DHC A;  5LSC A;  3T3O A;  2BG7 A;  4EYB A;  3IOG A;  4WD6 A;  2WYM C;  5A5Z A;  4C1E A;  3RPC A;  3WXC A;  4EXS A;  2FHX A;  3RKJ A;  3KNR A;  3PY6 A;  5ACQ A;  4HL1 A;  4TZB A;  3BC2 A;  2Y8A A;  3AF6 A;  3QH8 A;  4C1C A;  4UWO B;  1JJT A;  4Z67 A;  2YNV A;  2NZF A;  2BFZ A;  2GKL A;  2QED A;  1YCH A;  3SD9 A;  5B1U A;  4RAW A;  2BC2 A;  1KO3 A;  2DKF A;  2GMN A;  2DOO A;  2BFZ B;  4DIL A;  4ZNB A;  1X8I A;  4Z5Z A;  2BTN A;  2BG6 A;  3KL7 A;  5KIK A;  2BGA A;  4NQ5 A;  1YCG A;  5EVK A;  5A0T A;  1P9E A;  1X8G A;  2WRS A;  3Q6V A;  2R2D A;  2Q9U A;  3I13 A;  3PY5 A;  3F9O A;  2QDS A;  4KEQ A;  4XWW A;  2WYM A;  5B3R A;  1ZKP A;  1MQO A;  4Z60 A;  2BG2 A;  2AZ4 A;  4FEK A;  5LS3 A;  4FR7 A;  4D1W A;  2OHJ A;  1X8H A;  2YNU A;  2QJS A;  1WUO A;  4NQ4 A;  2BMI A;  2P1E A;  4BZ3 A;  2CBN A;  4GYQ A;  4YSB A;  5DPX A;  4GYU A;  3I15 A;  2BIB A;  2I7T A;  3A4Y A;  1XM8 A;  1KO2 A;  5HH4 A;  4C1F A;  1QH5 A;  2Q0J A;  4Z7R A;  1L9Y A;  4D02 A;  4RBS A;  2ZO4 A;  4RL0 A;  4D1V A;  2UYX A;  4O98 A;  5FQB A;  4TZF A;  4C1H A;  5ACX A;  2GFK A;  5HH6 A;  5A0V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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