5LCAA

Vim-2 metallo-beta-lactamase in complex with 3-oxo-2-(3-(trifluoromethyl)phenyl)isoindoline-4-carboxylic acid (compound 17)
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
222
structure length
222
Chain Sequence
IPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title NMR-filtered virtual screening leads to non-metal chelating metallo-beta-lactamase inhibitors.
pubmed doi rcsb
source organism Pseudomonas aeruginosa
molecule tags Hydrolase
molecule keywords Metallo-beta-lactamase VIM-2
total genus 69
structure length 222
sequence length 222
ec nomenclature
pdb deposition date 2016-06-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5lcaA00
2P18A 5IQKA 5HH6A 2CBNA 2I7VA 4D1UA 4Z60A 2FK6A 4ZEJA 4UWRB 4HKYA 4RBSA 3PG4A 3KL7A 1VMEA 4FR7A 3IDZA 4UBQA 4C1HA 3DHAA 4TZEA 2DKFA 2FHXA 2NZEA 4U4LA 1DD6A 3IEKA 3S0ZA 2I7TA 4HL1A 3T3NA 2P97A 4CHLA 1YCHA 3MD7A 5B1UA 2YCBA 2GFJA 2BFLA 3I15A 2DOOA 3KNSA 4C09A 2YZ3A 3ZR9A 3RKJA 1KR3A 1WUOA 5AEBA 4Z5ZA 2E7YA 2VW8A 1WRAA 5K0WA 4EYFA 2BIBA 2P1EA 2YNTA 5ACVA 1YCFA 5FQAA 2BFZB 3I14A 3IOFA 1K07A 4EYBA 2A7MA 5EV6A 2ZNBA 3SD9A 3F9OA 3BC2A 1A7TA 1VGNA 5EVBA 2FHXB 4NQ6A 5ACUA 3LVZA 2GFKA 3ZWFA 4Z6XA 4PVOA 4H0DA 3ZNBA 4YSLA 3T3OA 3VQZA 1DXKA 2FU7A 4D1VA 2I7XA 5K4MA 1DDKA 3IE0A 3DH8A 4Z7RA 4XWWA 4Z67A 3X2YA 2YNUA 4B87A 2BG8A 3X2ZA 3QH8A 5LE1A 4GYQA 2WYMA 1QH3A 2QEDA 5ACRA 4KEQA 2BG6A 2AIOA 2XF4A 2WRSA 4UWSB 1JT1A 3RKKA 4FEKA 3PY5A 4TYFA 2BR6A 5ACPA 4RL2A 4Z5YA 4DILA 5HIPA 1L9YA 2OHHA 3I0VA 2BGAA 5KIKA 3G1PA 1ZTCA 1Y44A 4AD9A 4RL0A 3SFPA 4O98A 4UAMA 4GCWA 4TZBA 4F6HA 4C1EA 2Y8BA 3P2UA 3AF5A 5EH9A 5EVDA 3PY6A 5B3RA 3A4YA 2GMNA 4F6ZA 3WXCA 5ACTA 3L6NA 3IOGA 3VPEA 5A0TA 5EV8A 5ACSA 2M5DA 3FAIA 4EXSA 3IELA 3X2XA 4ZNBA 2YNVA 1M2XA 4D02A 4DIKA 5LM6A 1A8TA 3BK1A 3AJ3A 4XWTA 1JJEA 5AXRA 5LS3A 3IE1A 2Q9UA 1VJNA 3Q6VA 3DHCA 5AXOA 3ZQ4A 2UYXA 2NYPA 5KILA 5FQBA 4TZFA 5LMCA 4EXYA 5AYAA 2ZWRA 5EVKA 3ESHA 5K4NA 2HB9A 2QDTA 1YCGA 3RPCA 2WYMC 4EY2A 1WUPA 2NZFA 4UA4A 3X30A 2BMIA 2OHIA 5A5ZA 1E5DA 1XM8A 1X8IA 2P4ZA 5HH5A 2QJSA 4ZO2A 4C1DA 2YNTB 3I13A 5HIOA 4ZO3A 4TZ9A 1BC2A 4D1TA 1QH5A 1KO3A 4YSBA 4KEPA 4P62A 1WW1A 1XTOA 2GCUA 5ACQA 5A0VA 3KNRA 3TP9A 3SRXA 2OHJA 2QINA 2WHGA 2Y87A 4J5HA 5DPXA 2M5CA 5HIQA 4YSKA 4RAMA 4AX0B 2WYLA 5AHRA 2Q0IA 3I11A 2QDSA 4D1WA 2Q42A 2BFZA 2AZ4A 4TYTA 3SW3A 2BG8B 4C1CA 4LE6A 2FU9A 2FU6A 3AF6A 5EWAA 2H6AA 4C1GA 1ZNBA 4AWZA 1P9EA 3H3EA 2Y8AA 2GKLA 2ZZIA 3SPUA 5HISA 3SBLA 1HLKA 5LLDA 4UWOB 5LCHA 2XR1A 5HH4A 2BC2A 1BMCA 1SMLA 4HL2A 4UWPB 4GYUA 5AHOA 4RM5A 3DHBA 4EYLA 4NQ5A 5LCFA 5EHTA 4AWYB 3FCZA 3R2UA 1MQOA 5EW0A 2BFKA 5FQCA 5A87A 5LCAA 3JXPA 4XUKA 1X8HA 1JJTA 1X8GA 3IE2A 2BG2A 5LSCA 4AX1B 4BZ3A 2YNVB 2FM6A 5ACXA 2BTNA 4EFZA 1ZKPA 2ZO4A 3IEMA 2Q0JA 4PVTA 4NQ4A 3ADRA 2BG7A 2R2DA 4FSBA 1BVTA 5B15A 5K4KA 4J5FA 1KO2A 3BK2A 4C1FA 4JO0A 3T9MA 4RAWA 2NXAA 5ACWA 2FU8A 3BV6A 4NQ2A 4BP0A 4WD6A 2YNWA 4V0HA
chains in the Genus database with same CATH superfamily
2P18A 5IQKA 5HH6A 2CBNA 2I7VA 4D1UA 4Z60A 2FK6A 4ZEJA 4UWRB 4HKYA 4RBSA 3PG4A 3KL7A 1VMEA 4FR7A 3IDZA 4UBQA 4C1HA 3DHAA 4TZEA 2DKFA 2FHXA 2NZEA 4U4LA 1DD6A 3IEKA 3S0ZA 4NURA 2I7TA 4HL1A 3T3NA 2P97A 4CHLA 1YCHA 3MD7A 5B1UA 2YCBA 2GFJA 2BFLA 3I15A 2DOOA 3KNSA 4C09A 2YZ3A 3ZR9A 3RKJA 1KR3A 1WUOA 5AEBA 4Z5ZA 2E7YA 2VW8A 1WRAA 5K0WA 4EYFA 2BIBA 2P1EA 2YNTA 5ACVA 1YCFA 5FQAA 2BFZB 3I14A 3IOFA 1K07A 4EYBA 2A7MA 5EV6A 2ZNBA 3SD9A 3F9OA 3BC2A 1A7TA 1VGNA 5EVBA 2FHXB 4NQ6A 5ACUA 3LVZA 2GFKA 3ZWFA 4Z6XA 4PVOA 4H0DA 3ZNBA 4YSLA 3T3OA 3VQZA 1DXKA 2FU7A 4D1VA 2I7XA 5K4MA 1DDKA 3IE0A 3DH8A 4Z7RA 4XWWA 4Z67A 3X2YA 2YNUA 4B87A 2BG8A 3X2ZA 3QH8A 5LE1A 4GYQA 2WYMA 1QH3A 2QEDA 2YHEA 5ACRA 4KEQA 2BG6A 2AIOA 2XF4A 2WRSA 4UWSB 1JT1A 3RKKA 4FEKA 5AJLA 3PY5A 4TYFA 2BR6A 5ACPA 4RL2A 4Z5YA 4DILA 5HIPA 1L9YA 2OHHA 3I0VA 2BGAA 5KIKA 3G1PA 1ZTCA 1Y44A 4AD9A 4RL0A 3SFPA 4O98A 4UAMA 4GCWA 4TZBA 4F6HA 4C1EA 2Y8BA 3P2UA 3AF5A 5EH9A 5EVDA 3PY6A 5B3RA 3A4YA 2GMNA 4F6ZA 3WXCA 5ACTA 3L6NA 3IOGA 3VPEA 5A0TA 5EV8A 5ACSA 2M5DA 3FAIA 4EXSA 3IELA 3X2XA 4ZNBA 4AXHA 5A23A 2YNVA 1M2XA 4D02A 4DIKA 5LM6A 1A8TA 3BK1A 3AJ3A 4XWTA 1JJEA 5AXRA 5LS3A 3IE1A 2Q9UA 1VJNA 3Q6VA 3DHCA 5AXOA 3ZQ4A 2UYXA 2CFUA 2CFZA 2NYPA 5KILA 5FQBA 4TZFA 5LMCA 4EXYA 5AYAA 2ZWRA 5EVKA 3ESHA 5K4NA 2HB9A 2QDTA 1YCGA 3RPCA 2WYMC 4EY2A 1WUPA 2NZFA 4UA4A 3X30A 2BMIA 2OHIA 5A5ZA 1E5DA 1XM8A 1X8IA 2P4ZA 5HH5A 2QJSA 4ZO2A 4C1DA 2YNTB 3I13A 5HIOA 4ZO3A 4TZ9A 1BC2A 4D1TA 1QH5A 1KO3A 4YSBA 4KEPA 4P62A 1WW1A 1XTOA 2GCUA 5ACQA 5A0VA 3KNRA 3TP9A 3SRXA 2OHJA 2CG2A 2QINA 2WHGA 2Y87A 4J5HA 5DPXA 2M5CA 4AV7A 5HIQA 4YSKA 4RAMA 4AX0B 2WYLA 5AHRA 2Q0IA 3I11A 2QDSA 4D1WA 2Q42A 2BFZA 2AZ4A 4TYTA 3SW3A 2BG8B 4C1CA 4LE6A 2FU9A 2FU6A 3AF6A 5EWAA 2H6AA 4C1GA 1ZNBA 2CG3A 4AWZA 1P9EA 3H3EA 2Y8AA 2GKLA 2ZZIA 3SPUA 5HISA 3SBLA 1HLKA 5LLDA 4UWOB 5LCHA 2XR1A 5HH4A 2BC2A 1BMCA 1SMLA 4HL2A 4UWPB 4GYUA 5AHOA 4RM5A 3DHBA 4EYLA 4NQ5A 4PDXA 5LCFA 5EHTA 4AWYB 3FCZA 3R2UA 1MQOA 5EW0A 2BFKA 5FQCA 5A87A 5LCAA 3JXPA 4XUKA 1X8HA 5AIJA 1JJTA 1X8GA 3IE2A 2BG2A 5LSCA 4AX1B 4BZ3A 2YNVB 2FM6A 5ACXA 2BTNA 4EFZA 1ZKPA 2ZO4A 3IEMA 2Q0JA 4PVTA 4NQ4A 3ADRA 2BG7A 2R2DA 4FSBA 1BVTA 5B15A 5K4KA 4J5FA 1KO2A 3BK2A 4C1FA 4JO0A 3T9MA 4RAWA 2NXAA 5ACWA 2FU8A 3BV6A 4NQ2A 4BP0A 4WD6A 2YNWA 4V0HA
chains in the Genus database with same CATH topology
2P18A 5IQKA 5HH6A 2CBNA 2I7VA 4D1UA 4Z60A 2FK6A 4ZEJA 4UWRB 4HKYA 4RBSA 3PG4A 3KL7A 1VMEA 4FR7A 3IDZA 4UBQA 4C1HA 3DHAA 4TZEA 2DKFA 2FHXA 2NZEA 4U4LA 1DD6A 3IEKA 3S0ZA 2I7TA 4HL1A 3T3NA 2P97A 4CHLA 1YCHA 3MD7A 5B1UA 2YCBA 2GFJA 2BFLA 3I15A 2DOOA 3KNSA 4C09A 2YZ3A 3ZR9A 3RKJA 1KR3A 1WUOA 5AEBA 4Z5ZA 2E7YA 2VW8A 1WRAA 5K0WA 4EYFA 2BIBA 2P1EA 2YNTA 5ACVA 1YCFA 5FQAA 2BFZB 3I14A 3IOFA 1K07A 4EYBA 2A7MA 5EV6A 2ZNBA 3SD9A 3F9OA 3BC2A 1A7TA 1VGNA 5EVBA 2FHXB 4NQ6A 5ACUA 3LVZA 2GFKA 3ZWFA 4Z6XA 4PVOA 4H0DA 3ZNBA 4YSLA 3T3OA 3VQZA 1DXKA 2FU7A 4D1VA 2I7XA 5K4MA 1DDKA 3IE0A 3DH8A 4Z7RA 4XWWA 4Z67A 3X2YA 2YNUA 4B87A 2BG8A 3X2ZA 3QH8A 5LE1A 4GYQA 2WYMA 1QH3A 2QEDA 5ACRA 4KEQA 2BG6A 2AIOA 2XF4A 2WRSA 4UWSB 1JT1A 3RKKA 4FEKA 3PY5A 4TYFA 2BR6A 5ACPA 4RL2A 4Z5YA 4DILA 5HIPA 1L9YA 2OHHA 3I0VA 2BGAA 5KIKA 3G1PA 1ZTCA 1Y44A 4AD9A 4RL0A 3SFPA 4O98A 4UAMA 4GCWA 4TZBA 4F6HA 4C1EA 2Y8BA 3P2UA 3AF5A 5EH9A 5EVDA 3PY6A 5B3RA 3A4YA 2GMNA 4F6ZA 3WXCA 5ACTA 3L6NA 3IOGA 3VPEA 5A0TA 5EV8A 5ACSA 2M5DA 3FAIA 4EXSA 3IELA 3X2XA 4ZNBA 2YNVA 1M2XA 4D02A 4DIKA 5LM6A 1A8TA 3BK1A 3AJ3A 4XWTA 1JJEA 5AXRA 5LS3A 3IE1A 2Q9UA 1VJNA 3Q6VA 3DHCA 5AXOA 3ZQ4A 2UYXA 2NYPA 5KILA 5FQBA 4TZFA 5LMCA 4EXYA 5AYAA 2ZWRA 5EVKA 3ESHA 5K4NA 2HB9A 2QDTA 1YCGA 3RPCA 2WYMC 4EY2A 1WUPA 2NZFA 4UA4A 3X30A 2BMIA 2OHIA 5A5ZA 1E5DA 1XM8A 1X8IA 2P4ZA 5HH5A 2QJSA 4ZO2A 4C1DA 2YNTB 3I13A 5HIOA 4ZO3A 4TZ9A 1BC2A 4D1TA 1QH5A 1KO3A 4YSBA 4KEPA 4P62A 1WW1A 1XTOA 2GCUA 5ACQA 5A0VA 3KNRA 3TP9A 3SRXA 2OHJA 2QINA 2WHGA 2Y87A 4J5HA 5DPXA 2M5CA 5HIQA 4YSKA 4RAMA 4AX0B 2WYLA 5AHRA 2Q0IA 3I11A 2QDSA 4D1WA 2Q42A 2BFZA 2AZ4A 4TYTA 3SW3A 2BG8B 4C1CA 4LE6A 2FU9A 2FU6A 3AF6A 5EWAA 2H6AA 4C1GA 1ZNBA 4AWZA 1P9EA 3H3EA 2Y8AA 2GKLA 2ZZIA 3SPUA 5HISA 3SBLA 1HLKA 5LLDA 4UWOB 5LCHA 2XR1A 5HH4A 2BC2A 1BMCA 1SMLA 4HL2A 4UWPB 4GYUA 5AHOA 4RM5A 3DHBA 4EYLA 4NQ5A 5LCFA 5EHTA 4AWYB 3FCZA 3R2UA 1MQOA 5EW0A 2BFKA 5FQCA 5A87A 5LCAA 3JXPA 4XUKA 1X8HA 1JJTA 1X8GA 3IE2A 2BG2A 5LSCA 4AX1B 4BZ3A 2YNVB 2FM6A 5ACXA 2BTNA 4EFZA 1ZKPA 2ZO4A 3IEMA 2Q0JA 4PVTA 4NQ4A 3ADRA 2BG7A 2R2DA 4FSBA 1BVTA 5B15A 5K4KA 4J5FA 1KO2A 3BK2A 4C1FA 4JO0A 3T9MA 4RAWA 2NXAA 5ACWA 2FU8A 3BV6A 4NQ2A 4BP0A 4WD6A 2YNWA 4V0HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2P18 A;  5IQK A;  5HH6 A;  2CBN A;  2I7V A;  4D1U A;  4Z60 A;  2FK6 A;  4ZEJ A;  4UWR B;  4HKY A;  4RBS A;  3PG4 A;  3KL7 A;  1VME A;  4FR7 A;  3IDZ A;  4UBQ A;  4C1H A;  3DHA A;  4TZE A;  2DKF A;  2FHX A;  2NZE A;  4U4L A;  1DD6 A;  3IEK A;  3S0Z A;  2I7T A;  4HL1 A;  3T3N A;  2P97 A;  4CHL A;  1YCH A;  3MD7 A;  5B1U A;  2YCB A;  2GFJ A;  2BFL A;  3I15 A;  2DOO A;  3KNS A;  4C09 A;  2YZ3 A;  3ZR9 A;  3RKJ A;  1KR3 A;  1WUO A;  5AEB A;  4Z5Z A;  2E7Y A;  2VW8 A;  1WRA A;  5K0W A;  4EYF A;  2BIB A;  2P1E A;  2YNT A;  5ACV A;  1YCF A;  5FQA A;  2BFZ B;  3I14 A;  3IOF A;  1K07 A;  4EYB A;  2A7M A;  5EV6 A;  2ZNB A;  3SD9 A;  3F9O A;  3BC2 A;  1A7T A;  1VGN A;  5EVB A;  2FHX B;  4NQ6 A;  5ACU A;  3LVZ A;  2GFK A;  3ZWF A;  4Z6X A;  4PVO A;  4H0D A;  3ZNB A;  4YSL A;  3T3O A;  3VQZ A;  1DXK A;  2FU7 A;  4D1V A;  2I7X A;  5K4M A;  1DDK A;  3IE0 A;  3DH8 A;  4Z7R A;  4XWW A;  4Z67 A;  3X2Y A;  2YNU A;  4B87 A;  2BG8 A;  3X2Z A;  3QH8 A;  5LE1 A;  4GYQ A;  2WYM A;  1QH3 A;  2QED A;  5ACR A;  4KEQ A;  2BG6 A;  2AIO A;  2XF4 A;  2WRS A;  4UWS B;  1JT1 A;  3RKK A;  4FEK A;  3PY5 A;  4TYF A;  2BR6 A;  5ACP A;  4RL2 A;  4Z5Y A;  4DIL A;  5HIP A;  1L9Y A;  2OHH A;  3I0V A;  2BGA A;  5KIK A;  3G1P A;  1ZTC A;  1Y44 A;  4AD9 A;  4RL0 A;  3SFP A;  4O98 A;  4UAM A;  4GCW A;  4TZB A;  4F6H A;  4C1E A;  2Y8B A;  3P2U A;  3AF5 A;  5EH9 A;  5EVD A;  3PY6 A;  5B3R A;  3A4Y A;  2GMN A;  4F6Z A;  3WXC A;  5ACT A;  3L6N A;  3IOG A;  3VPE A;  5A0T A;  5EV8 A;  5ACS A;  2M5D A;  3FAI A;  4EXS A;  3IEL A;  3X2X A;  4ZNB A;  2YNV A;  1M2X A;  4D02 A;  4DIK A;  5LM6 A;  1A8T A;  3BK1 A;  3AJ3 A;  4XWT A;  1JJE A;  5AXR A;  5LS3 A;  3IE1 A;  2Q9U A;  1VJN A;  3Q6V A;  3DHC A;  5AXO A;  3ZQ4 A;  2UYX A;  2NYP A;  5KIL A;  5FQB A;  4TZF A;  5LMC A;  4EXY A;  5AYA A;  2ZWR A;  5EVK A;  3ESH A;  5K4N A;  2HB9 A;  2QDT A;  1YCG A;  3RPC A;  2WYM C;  4EY2 A;  1WUP A;  2NZF A;  4UA4 A;  3X30 A;  2BMI A;  2OHI A;  5A5Z A;  1E5D A;  1XM8 A;  1X8I A;  2P4Z A;  5HH5 A;  2QJS A;  4ZO2 A;  4C1D A;  2YNT B;  3I13 A;  5HIO A;  4ZO3 A;  4TZ9 A;  1BC2 A;  4D1T A;  1QH5 A;  1KO3 A;  4YSB A;  4KEP A;  4P62 A;  1WW1 A;  1XTO A;  2GCU A;  5ACQ A;  5A0V A;  3KNR A;  3TP9 A;  3SRX A;  2OHJ A;  2QIN A;  2WHG A;  2Y87 A;  4J5H A;  5DPX A;  2M5C A;  5HIQ A;  4YSK A;  4RAM A;  4AX0 B;  2WYL A;  5AHR A;  2Q0I A;  3I11 A;  2QDS A;  4D1W A;  2Q42 A;  2BFZ A;  2AZ4 A;  4TYT A;  3SW3 A;  2BG8 B;  4C1C A;  4LE6 A;  2FU9 A;  2FU6 A;  3AF6 A;  5EWA A;  2H6A A;  4C1G A;  1ZNB A;  4AWZ A;  1P9E A;  3H3E A;  2Y8A A;  2GKL A;  2ZZI A;  3SPU A;  5HIS A;  3SBL A;  1HLK A;  5LLD A;  4UWO B;  5LCH A;  2XR1 A;  5HH4 A;  2BC2 A;  1BMC A;  1SML A;  4HL2 A;  4UWP B;  4GYU A;  5AHO A;  4RM5 A;  3DHB A;  4EYL A;  4NQ5 A;  5LCF A;  5EHT A;  4AWY B;  3FCZ A;  3R2U A;  1MQO A;  5EW0 A;  2BFK A;  5FQC A;  5A87 A;  5LCA A;  3JXP A;  4XUK A;  1X8H A;  1JJT A;  1X8G A;  3IE2 A;  2BG2 A;  5LSC A;  4AX1 B;  4BZ3 A;  2YNV B;  2FM6 A;  5ACX A;  2BTN A;  4EFZ A;  1ZKP A;  2ZO4 A;  3IEM A;  2Q0J A;  4PVT A;  4NQ4 A;  3ADR A;  2BG7 A;  2R2D A;  4FSB A;  1BVT A;  5B15 A;  5K4K A;  4J5F A;  1KO2 A;  3BK2 A;  4C1F A;  4JO0 A;  3T9M A;  4RAW A;  2NXA A;  5ACW A;  2FU8 A;  3BV6 A;  4NQ2 A;  4BP0 A;  4WD6 A;  2YNW A;  4V0H A; 
#chains in the Genus database with same CATH topology
 2P18 A;  5IQK A;  5HH6 A;  2CBN A;  2I7V A;  4D1U A;  4Z60 A;  2FK6 A;  4ZEJ A;  4UWR B;  4HKY A;  4RBS A;  3PG4 A;  3KL7 A;  1VME A;  4FR7 A;  3IDZ A;  4UBQ A;  4C1H A;  3DHA A;  4TZE A;  2DKF A;  2FHX A;  2NZE A;  4U4L A;  1DD6 A;  3IEK A;  3S0Z A;  4NUR A;  2I7T A;  4HL1 A;  3T3N A;  2P97 A;  4CHL A;  1YCH A;  3MD7 A;  5B1U A;  2YCB A;  2GFJ A;  2BFL A;  3I15 A;  2DOO A;  3KNS A;  4C09 A;  2YZ3 A;  3ZR9 A;  3RKJ A;  1KR3 A;  1WUO A;  5AEB A;  4Z5Z A;  2E7Y A;  2VW8 A;  1WRA A;  5K0W A;  4EYF A;  2BIB A;  2P1E A;  2YNT A;  5ACV A;  1YCF A;  5FQA A;  2BFZ B;  3I14 A;  3IOF A;  1K07 A;  4EYB A;  2A7M A;  5EV6 A;  2ZNB A;  3SD9 A;  3F9O A;  3BC2 A;  1A7T A;  1VGN A;  5EVB A;  2FHX B;  4NQ6 A;  5ACU A;  3LVZ A;  2GFK A;  3ZWF A;  4Z6X A;  4PVO A;  4H0D A;  3ZNB A;  4YSL A;  3T3O A;  3VQZ A;  1DXK A;  2FU7 A;  4D1V A;  2I7X A;  5K4M A;  1DDK A;  3IE0 A;  3DH8 A;  4Z7R A;  4XWW A;  4Z67 A;  3X2Y A;  2YNU A;  4B87 A;  2BG8 A;  3X2Z A;  3QH8 A;  5LE1 A;  4GYQ A;  2WYM A;  1QH3 A;  2QED A;  2YHE A;  5ACR A;  4KEQ A;  2BG6 A;  2AIO A;  2XF4 A;  2WRS A;  4UWS B;  1JT1 A;  3RKK A;  4FEK A;  5AJL A;  3PY5 A;  4TYF A;  2BR6 A;  5ACP A;  4RL2 A;  4Z5Y A;  4DIL A;  5HIP A;  1L9Y A;  2OHH A;  3I0V A;  2BGA A;  5KIK A;  3G1P A;  1ZTC A;  1Y44 A;  4AD9 A;  4RL0 A;  3SFP A;  4O98 A;  4UAM A;  4GCW A;  4TZB A;  4F6H A;  4C1E A;  2Y8B A;  3P2U A;  3AF5 A;  5EH9 A;  5EVD A;  3PY6 A;  5B3R A;  3A4Y A;  2GMN A;  4F6Z A;  3WXC A;  5ACT A;  3L6N A;  3IOG A;  3VPE A;  5A0T A;  5EV8 A;  5ACS A;  2M5D A;  3FAI A;  4EXS A;  3IEL A;  3X2X A;  4ZNB A;  4AXH A;  5A23 A;  2YNV A;  1M2X A;  4D02 A;  4DIK A;  5LM6 A;  1A8T A;  3BK1 A;  3AJ3 A;  4XWT A;  1JJE A;  5AXR A;  5LS3 A;  3IE1 A;  2Q9U A;  1VJN A;  3Q6V A;  3DHC A;  5AXO A;  3ZQ4 A;  2UYX A;  2CFU A;  2CFZ A;  2NYP A;  5KIL A;  5FQB A;  4TZF A;  5LMC A;  4EXY A;  5AYA A;  2ZWR A;  5EVK A;  3ESH A;  5K4N A;  2HB9 A;  2QDT A;  1YCG A;  3RPC A;  2WYM C;  4EY2 A;  1WUP A;  2NZF A;  4UA4 A;  3X30 A;  2BMI A;  2OHI A;  5A5Z A;  1E5D A;  1XM8 A;  1X8I A;  2P4Z A;  5HH5 A;  2QJS A;  4ZO2 A;  4C1D A;  2YNT B;  3I13 A;  5HIO A;  4ZO3 A;  4TZ9 A;  1BC2 A;  4D1T A;  1QH5 A;  1KO3 A;  4YSB A;  4KEP A;  4P62 A;  1WW1 A;  1XTO A;  2GCU A;  5ACQ A;  5A0V A;  3KNR A;  3TP9 A;  3SRX A;  2OHJ A;  2CG2 A;  2QIN A;  2WHG A;  2Y87 A;  4J5H A;  5DPX A;  2M5C A;  4AV7 A;  5HIQ A;  4YSK A;  4RAM A;  4AX0 B;  2WYL A;  5AHR A;  2Q0I A;  3I11 A;  2QDS A;  4D1W A;  2Q42 A;  2BFZ A;  2AZ4 A;  4TYT A;  3SW3 A;  2BG8 B;  4C1C A;  4LE6 A;  2FU9 A;  2FU6 A;  3AF6 A;  5EWA A;  2H6A A;  4C1G A;  1ZNB A;  2CG3 A;  4AWZ A;  1P9E A;  3H3E A;  2Y8A A;  2GKL A;  2ZZI A;  3SPU A;  5HIS A;  3SBL A;  1HLK A;  5LLD A;  4UWO B;  5LCH A;  2XR1 A;  5HH4 A;  2BC2 A;  1BMC A;  1SML A;  4HL2 A;  4UWP B;  4GYU A;  5AHO A;  4RM5 A;  3DHB A;  4EYL A;  4NQ5 A;  4PDX A;  5LCF A;  5EHT A;  4AWY B;  3FCZ A;  3R2U A;  1MQO A;  5EW0 A;  2BFK A;  5FQC A;  5A87 A;  5LCA A;  3JXP A;  4XUK A;  1X8H A;  5AIJ A;  1JJT A;  1X8G A;  3IE2 A;  2BG2 A;  5LSC A;  4AX1 B;  4BZ3 A;  2YNV B;  2FM6 A;  5ACX A;  2BTN A;  4EFZ A;  1ZKP A;  2ZO4 A;  3IEM A;  2Q0J A;  4PVT A;  4NQ4 A;  3ADR A;  2BG7 A;  2R2D A;  4FSB A;  1BVT A;  5B15 A;  5K4K A;  4J5F A;  1KO2 A;  3BK2 A;  4C1F A;  4JO0 A;  3T9M A;  4RAW A;  2NXA A;  5ACW A;  2FU8 A;  3BV6 A;  4NQ2 A;  4BP0 A;  4WD6 A;  2YNW A;  4V0H A; 
#chains in the Genus database with same CATH homology
 2P18 A;  5IQK A;  5HH6 A;  2CBN A;  2I7V A;  4D1U A;  4Z60 A;  2FK6 A;  4ZEJ A;  4UWR B;  4HKY A;  4RBS A;  3PG4 A;  3KL7 A;  1VME A;  4FR7 A;  3IDZ A;  4UBQ A;  4C1H A;  3DHA A;  4TZE A;  2DKF A;  2FHX A;  2NZE A;  4U4L A;  1DD6 A;  3IEK A;  3S0Z A;  2I7T A;  4HL1 A;  3T3N A;  2P97 A;  4CHL A;  1YCH A;  3MD7 A;  5B1U A;  2YCB A;  2GFJ A;  2BFL A;  3I15 A;  2DOO A;  3KNS A;  4C09 A;  2YZ3 A;  3ZR9 A;  3RKJ A;  1KR3 A;  1WUO A;  5AEB A;  4Z5Z A;  2E7Y A;  2VW8 A;  1WRA A;  5K0W A;  4EYF A;  2BIB A;  2P1E A;  2YNT A;  5ACV A;  1YCF A;  5FQA A;  2BFZ B;  3I14 A;  3IOF A;  1K07 A;  4EYB A;  2A7M A;  5EV6 A;  2ZNB A;  3SD9 A;  3F9O A;  3BC2 A;  1A7T A;  1VGN A;  5EVB A;  2FHX B;  4NQ6 A;  5ACU A;  3LVZ A;  2GFK A;  3ZWF A;  4Z6X A;  4PVO A;  4H0D A;  3ZNB A;  4YSL A;  3T3O A;  3VQZ A;  1DXK A;  2FU7 A;  4D1V A;  2I7X A;  5K4M A;  1DDK A;  3IE0 A;  3DH8 A;  4Z7R A;  4XWW A;  4Z67 A;  3X2Y A;  2YNU A;  4B87 A;  2BG8 A;  3X2Z A;  3QH8 A;  5LE1 A;  4GYQ A;  2WYM A;  1QH3 A;  2QED A;  5ACR A;  4KEQ A;  2BG6 A;  2AIO A;  2XF4 A;  2WRS A;  4UWS B;  1JT1 A;  3RKK A;  4FEK A;  3PY5 A;  4TYF A;  2BR6 A;  5ACP A;  4RL2 A;  4Z5Y A;  4DIL A;  5HIP A;  1L9Y A;  2OHH A;  3I0V A;  2BGA A;  5KIK A;  3G1P A;  1ZTC A;  1Y44 A;  4AD9 A;  4RL0 A;  3SFP A;  4O98 A;  4UAM A;  4GCW A;  4TZB A;  4F6H A;  4C1E A;  2Y8B A;  3P2U A;  3AF5 A;  5EH9 A;  5EVD A;  3PY6 A;  5B3R A;  3A4Y A;  2GMN A;  4F6Z A;  3WXC A;  5ACT A;  3L6N A;  3IOG A;  3VPE A;  5A0T A;  5EV8 A;  5ACS A;  2M5D A;  3FAI A;  4EXS A;  3IEL A;  3X2X A;  4ZNB A;  2YNV A;  1M2X A;  4D02 A;  4DIK A;  5LM6 A;  1A8T A;  3BK1 A;  3AJ3 A;  4XWT A;  1JJE A;  5AXR A;  5LS3 A;  3IE1 A;  2Q9U A;  1VJN A;  3Q6V A;  3DHC A;  5AXO A;  3ZQ4 A;  2UYX A;  2NYP A;  5KIL A;  5FQB A;  4TZF A;  5LMC A;  4EXY A;  5AYA A;  2ZWR A;  5EVK A;  3ESH A;  5K4N A;  2HB9 A;  2QDT A;  1YCG A;  3RPC A;  2WYM C;  4EY2 A;  1WUP A;  2NZF A;  4UA4 A;  3X30 A;  2BMI A;  2OHI A;  5A5Z A;  1E5D A;  1XM8 A;  1X8I A;  2P4Z A;  5HH5 A;  2QJS A;  4ZO2 A;  4C1D A;  2YNT B;  3I13 A;  5HIO A;  4ZO3 A;  4TZ9 A;  1BC2 A;  4D1T A;  1QH5 A;  1KO3 A;  4YSB A;  4KEP A;  4P62 A;  1WW1 A;  1XTO A;  2GCU A;  5ACQ A;  5A0V A;  3KNR A;  3TP9 A;  3SRX A;  2OHJ A;  2QIN A;  2WHG A;  2Y87 A;  4J5H A;  5DPX A;  2M5C A;  5HIQ A;  4YSK A;  4RAM A;  4AX0 B;  2WYL A;  5AHR A;  2Q0I A;  3I11 A;  2QDS A;  4D1W A;  2Q42 A;  2BFZ A;  2AZ4 A;  4TYT A;  3SW3 A;  2BG8 B;  4C1C A;  4LE6 A;  2FU9 A;  2FU6 A;  3AF6 A;  5EWA A;  2H6A A;  4C1G A;  1ZNB A;  4AWZ A;  1P9E A;  3H3E A;  2Y8A A;  2GKL A;  2ZZI A;  3SPU A;  5HIS A;  3SBL A;  1HLK A;  5LLD A;  4UWO B;  5LCH A;  2XR1 A;  5HH4 A;  2BC2 A;  1BMC A;  1SML A;  4HL2 A;  4UWP B;  4GYU A;  5AHO A;  4RM5 A;  3DHB A;  4EYL A;  4NQ5 A;  5LCF A;  5EHT A;  4AWY B;  3FCZ A;  3R2U A;  1MQO A;  5EW0 A;  2BFK A;  5FQC A;  5A87 A;  5LCA A;  3JXP A;  4XUK A;  1X8H A;  1JJT A;  1X8G A;  3IE2 A;  2BG2 A;  5LSC A;  4AX1 B;  4BZ3 A;  2YNV B;  2FM6 A;  5ACX A;  2BTN A;  4EFZ A;  1ZKP A;  2ZO4 A;  3IEM A;  2Q0J A;  4PVT A;  4NQ4 A;  3ADR A;  2BG7 A;  2R2D A;  4FSB A;  1BVT A;  5B15 A;  5K4K A;  4J5F A;  1KO2 A;  3BK2 A;  4C1F A;  4JO0 A;  3T9M A;  4RAW A;  2NXA A;  5ACW A;  2FU8 A;  3BV6 A;  4NQ2 A;  4BP0 A;  4WD6 A;  2YNW A;  4V0H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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