5LCAA

Vim-2 metallo-beta-lactamase in complex with 3-oxo-2-(3-(trifluoromethyl)phenyl)isoindoline-4-carboxylic acid (compound 17)
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
222
structure length
222
Chain Sequence
IPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Metallo-beta-lactamase VIM-2
publication title NMR-filtered virtual screening leads to non-metal chelating metallo-beta-lactamase inhibitors.
pubmed doi rcsb
source organism Pseudomonas aeruginosa
total genus 69
structure length 222
sequence length 222
ec nomenclature
pdb deposition date 2016-06-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5lcaA00
2FU8A 4NQ2A 3AF5A 4D1WA 1WRAA 4D02A 3BK2A 3X2XA 1X8GA 5EHTA 2Q0JA 1X8IA 2OHHA 2AIOA 2YNVA 3JXPA 4UBQA 2H6AA 2ZZIA 3ESHA 4NQ4A 4C1FA 5LLDA 4F6ZA 2Y87A 5AHOA 2P18A 4D1VA 4U4LA 4BP0A 2M5DA 2BR6A 5ACPA 1WUOA 2Y8AA 4EYBA 3IOFA 1P9EA 4EXYA 4WD6A 1VJNA 5EV8A 3PG4A 3ZWFA 2YNVB 2NZEA 2GMNA 2BGAA 2FU7A 3SRXA 5K0WA 1VMEA 3IDZA 2FK6A 5EVKA 5B15A 1A8TA 4TYTA 2GCUA 3ZR9A 3DH8A 5A87A 5LE1A 1WUPA 2NYPA 4UAMA 4J5FA 2BTNA 4O98A 4RAWA 3AJ3A 2Q0IA 3I0VA 3SW3A 3T3OA 2FHXA 5LS3A 4EY2A 2M5CA 4EXSA 4NQ5A 5FQCA 4UWSB 4KEPA 3KL7A 2ZO4A 1KO3A 2BC2A 2UYXA 3DHAA 5ACXA 5IQKA 2ZWRA 2WHGA 1HLKA 2CBNA 2QDTA 4V0HA 5EW0A 3RKKA 2WYMA 5HIQA 4PVTA 1QH5A 4GYQA 5ACWA 2BG8A 4ZO2A 4ZEJA 1ZNBA 4XWWA 3BC2A 4RAMA 3SPUA 1DXKA 1VGNA 2Q9UA 2Q42A 3DHBA 4GYUA 5ACRA 3X30A 4RL0A 5AYAA 1YCFA 1XM8A 5LCHA 5EVBA 3SBLA 3L6NA 5KIKA 1WW1A 5KILA 2BG8B 2BIBA 4FSBA 2P4ZA 3T3NA 2AZ4A 1KO2A 4PVOA 4Z5ZA 5HIOA 3F9OA 4TZEA 1A7TA 3I11A 4AD9A 3X2ZA 5AHRA 4Z6XA 2YNWA 4FR7A 2BFZA 2I7VA 5HH4A 4TZ9A 3DHCA 5DPXA 5HH5A 1XTOA 4NQ6A 4KEQA 5HH6A 4J5HA 3TP9A 1QH3A 4DILA 2YNTA 2GFJA 3PY5A 4UWRB 3LVZA 4GCWA 3RPCA 4TYFA 3IELA 2QEDA 4F6HA 4C1CA 4C09A 2YNUA 2BFZB 1JT1A 5LM6A 2NZFA 3IE0A 2BG2A 4C1GA 2VW8A 1E5DA 2DKFA 3S0ZA 2R2DA 2Y8BA 4YSLA 4EFZA 4CHLA 4D1UA 3I13A 4JO0A 2A7MA 4ZNBA 4RBSA 1BVTA 3IE1A 1M2XA 5LSCA 5EWAA 2I7TA 1BMCA 4Z67A 2FHXB 5HISA 3VPEA 4C1DA 3IOGA 3A4YA 5B1UA 4B87A 2DOOA 3SFPA 5ACQA 2BG7A 2WYLA 3BK1A 3IEMA 3Q6VA 5ACVA 3VQZA 4UA4A 3ZQ4A 1JJEA 3X2YA 2ZNBA 3R2UA 2BG6A 3T9MA 4HL2A 5EH9A 2E7YA 5EVDA 4Z60A 5LMCA 5AXRA 1L9YA 3KNRA 4UWPB 5A0VA 5LCAA 2QINA 4P62A 3IE2A 1JJTA 1X8HA 2BMIA 4Z7RA 5FQBA 4EYFA 4UWOB 2BFLA 4C1HA 2QDSA 5LCFA 2I7XA 1YCGA 4Z5YA 3PY6A 2FU9A 3G1PA 4ZO3A 3WXCA 3I14A 5A5ZA 3P2UA 4XWTA 3SD9A 3KNSA 1K07A 3AF6A 5ACSA 2YCBA 2FM6A 1DD6A 5AXOA 5AEBA 1ZTCA 2NXAA 4HKYA 3FCZA 3IEKA 4LE6A 1MQOA 4TZBA 5EV6A 3QH8A 5ACUA 4TZFA 2YNTB 2BFKA 5K4NA 3I15A 4AX1B 2XR1A 2QJSA 4D1TA 4BZ3A 2OHJA 2HB9A 1SMLA 3ADRA 4FEKA 2YZ3A 4HL1A 1YCHA 3MD7A 3RKJA 4H0DA 2OHIA 3ZNBA 2FU6A 1BC2A 1KR3A 1DDKA 4AWZA 2WRSA 4EYLA 4AWYB 4AX0B 5HIPA 5B3RA 4YSKA 3FAIA 5K4MA 2P97A 4DIKA 5A0TA 2WYMC 4C1EA 4YSBA 5K4KA 1ZKPA 2P1EA 2GKLA 4XUKA 2XF4A 4RM5A 4RL2A 5FQAA 5ACTA 3H3EA 3BV6A 1Y44A 2GFKA
chains in the Genus database with same CATH superfamily
2FU8A 4NQ2A 3AF5A 4D1WA 1WRAA 4D02A 3BK2A 3X2XA 1X8GA 5EHTA 2Q0JA 1X8IA 2OHHA 2AIOA 4AV7A 2YNVA 3JXPA 4UBQA 2H6AA 2ZZIA 3ESHA 4NQ4A 4C1FA 5LLDA 4F6ZA 2Y87A 5AHOA 2P18A 4D1VA 4U4LA 4BP0A 2M5DA 2BR6A 5ACPA 1WUOA 2Y8AA 4EYBA 3IOFA 1P9EA 4EXYA 4WD6A 1VJNA 5EV8A 3PG4A 3ZWFA 2YHEA 2YNVB 2NZEA 2GMNA 2BGAA 2FU7A 3SRXA 5K0WA 1VMEA 5A23A 3IDZA 2CG3A 2FK6A 5EVKA 5B15A 1A8TA 4TYTA 2GCUA 3ZR9A 3DH8A 5A87A 5LE1A 1WUPA 2NYPA 4UAMA 4J5FA 2BTNA 4O98A 4RAWA 3AJ3A 2Q0IA 3I0VA 3SW3A 3T3OA 2FHXA 5LS3A 4EY2A 2M5CA 4EXSA 4NQ5A 5FQCA 4UWSB 4KEPA 3KL7A 2ZO4A 1KO3A 2BC2A 2UYXA 3DHAA 5ACXA 5IQKA 2ZWRA 2WHGA 1HLKA 2CBNA 2QDTA 4V0HA 5EW0A 3RKKA 2WYMA 5HIQA 4PVTA 1QH5A 4GYQA 5ACWA 2BG8A 4ZO2A 4ZEJA 1ZNBA 4XWWA 3BC2A 4RAMA 3SPUA 1DXKA 1VGNA 2Q9UA 2Q42A 3DHBA 4GYUA 5ACRA 3X30A 2CG2A 4RL0A 5AYAA 1YCFA 1XM8A 5LCHA 5EVBA 3SBLA 3L6NA 5KIKA 1WW1A 5KILA 2BG8B 2BIBA 4FSBA 2P4ZA 3T3NA 2AZ4A 1KO2A 4PVOA 4Z5ZA 5HIOA 5AJLA 3F9OA 4TZEA 1A7TA 3I11A 4AD9A 3X2ZA 5AHRA 4Z6XA 2YNWA 4FR7A 2BFZA 2I7VA 5HH4A 4TZ9A 3DHCA 5DPXA 5HH5A 1XTOA 4NQ6A 4KEQA 5HH6A 4AXHA 4J5HA 3TP9A 1QH3A 4DILA 2YNTA 2GFJA 3PY5A 4UWRB 3LVZA 4GCWA 3RPCA 4TYFA 3IELA 2QEDA 4F6HA 4C1CA 4C09A 2YNUA 2BFZB 1JT1A 5LM6A 2NZFA 3IE0A 2BG2A 4C1GA 2VW8A 1E5DA 2DKFA 3S0ZA 2R2DA 2Y8BA 4YSLA 4EFZA 4CHLA 4D1UA 3I13A 4JO0A 2A7MA 4ZNBA 4RBSA 1BVTA 3IE1A 1M2XA 5LSCA 4PDXA 5EWAA 2I7TA 1BMCA 4Z67A 2FHXB 5HISA 3VPEA 4C1DA 3IOGA 3A4YA 5B1UA 4B87A 2DOOA 3SFPA 5ACQA 2BG7A 2WYLA 3BK1A 3IEMA 3Q6VA 5ACVA 2CFUA 3VQZA 4UA4A 3ZQ4A 1JJEA 3X2YA 2ZNBA 3R2UA 2BG6A 3T9MA 4HL2A 5EH9A 2E7YA 5EVDA 4Z60A 5LMCA 5AXRA 1L9YA 2CFZA 3KNRA 4UWPB 5A0VA 5LCAA 2QINA 4P62A 3IE2A 1JJTA 1X8HA 2BMIA 4Z7RA 5FQBA 5AIJA 4EYFA 4UWOB 2BFLA 4C1HA 2QDSA 5LCFA 2I7XA 1YCGA 4Z5YA 3PY6A 2FU9A 3G1PA 4ZO3A 3WXCA 3I14A 5A5ZA 3P2UA 4XWTA 3SD9A 3KNSA 1K07A 3AF6A 5ACSA 2YCBA 2FM6A 1DD6A 5AXOA 5AEBA 1ZTCA 2NXAA 4HKYA 3FCZA 3IEKA 4LE6A 1MQOA 4TZBA 5EV6A 3QH8A 5ACUA 4TZFA 2YNTB 2BFKA 5K4NA 3I15A 4AX1B 2XR1A 2QJSA 4D1TA 4BZ3A 2OHJA 2HB9A 1SMLA 3ADRA 4FEKA 2YZ3A 4HL1A 1YCHA 3MD7A 3RKJA 4H0DA 2OHIA 3ZNBA 2FU6A 1BC2A 1KR3A 1DDKA 4AWZA 2WRSA 4EYLA 4AWYB 4AX0B 5HIPA 5B3RA 4YSKA 3FAIA 5K4MA 4NURA 2P97A 4DIKA 5A0TA 2WYMC 4C1EA 4YSBA 5K4KA 1ZKPA 2P1EA 2GKLA 4XUKA 2XF4A 4RM5A 4RL2A 5FQAA 5ACTA 3H3EA 3BV6A 1Y44A 2GFKA
chains in the Genus database with same CATH topology
2FU8A 4NQ2A 3AF5A 4D1WA 1WRAA 4D02A 3BK2A 3X2XA 1X8GA 5EHTA 2Q0JA 1X8IA 2OHHA 2AIOA 2YNVA 3JXPA 4UBQA 2H6AA 2ZZIA 3ESHA 4NQ4A 4C1FA 5LLDA 4F6ZA 2Y87A 5AHOA 2P18A 4D1VA 4U4LA 4BP0A 2M5DA 2BR6A 5ACPA 1WUOA 2Y8AA 4EYBA 3IOFA 1P9EA 4EXYA 4WD6A 1VJNA 5EV8A 3PG4A 3ZWFA 2YNVB 2NZEA 2GMNA 2BGAA 2FU7A 3SRXA 5K0WA 1VMEA 3IDZA 2FK6A 5EVKA 5B15A 1A8TA 4TYTA 2GCUA 3ZR9A 3DH8A 5A87A 5LE1A 1WUPA 2NYPA 4UAMA 4J5FA 2BTNA 4O98A 4RAWA 3AJ3A 2Q0IA 3I0VA 3SW3A 3T3OA 2FHXA 5LS3A 4EY2A 2M5CA 4EXSA 4NQ5A 5FQCA 4UWSB 4KEPA 3KL7A 2ZO4A 1KO3A 2BC2A 2UYXA 3DHAA 5ACXA 5IQKA 2ZWRA 2WHGA 1HLKA 2CBNA 2QDTA 4V0HA 5EW0A 3RKKA 2WYMA 5HIQA 4PVTA 1QH5A 4GYQA 5ACWA 2BG8A 4ZO2A 4ZEJA 1ZNBA 4XWWA 3BC2A 4RAMA 3SPUA 1DXKA 1VGNA 2Q9UA 2Q42A 3DHBA 4GYUA 5ACRA 3X30A 4RL0A 5AYAA 1YCFA 1XM8A 5LCHA 5EVBA 3SBLA 3L6NA 5KIKA 1WW1A 5KILA 2BG8B 2BIBA 4FSBA 2P4ZA 3T3NA 2AZ4A 1KO2A 4PVOA 4Z5ZA 5HIOA 3F9OA 4TZEA 1A7TA 3I11A 4AD9A 3X2ZA 5AHRA 4Z6XA 2YNWA 4FR7A 2BFZA 2I7VA 5HH4A 4TZ9A 3DHCA 5DPXA 5HH5A 1XTOA 4NQ6A 4KEQA 5HH6A 4J5HA 3TP9A 1QH3A 4DILA 2YNTA 2GFJA 3PY5A 4UWRB 3LVZA 4GCWA 3RPCA 4TYFA 3IELA 2QEDA 4F6HA 4C1CA 4C09A 2YNUA 2BFZB 1JT1A 5LM6A 2NZFA 3IE0A 2BG2A 4C1GA 2VW8A 1E5DA 2DKFA 3S0ZA 2R2DA 2Y8BA 4YSLA 4EFZA 4CHLA 4D1UA 3I13A 4JO0A 2A7MA 4ZNBA 4RBSA 1BVTA 3IE1A 1M2XA 5LSCA 5EWAA 2I7TA 1BMCA 4Z67A 2FHXB 5HISA 3VPEA 4C1DA 3IOGA 3A4YA 5B1UA 4B87A 2DOOA 3SFPA 5ACQA 2BG7A 2WYLA 3BK1A 3IEMA 3Q6VA 5ACVA 3VQZA 4UA4A 3ZQ4A 1JJEA 3X2YA 2ZNBA 3R2UA 2BG6A 3T9MA 4HL2A 5EH9A 2E7YA 5EVDA 4Z60A 5LMCA 5AXRA 1L9YA 3KNRA 4UWPB 5A0VA 5LCAA 2QINA 4P62A 3IE2A 1JJTA 1X8HA 2BMIA 4Z7RA 5FQBA 4EYFA 4UWOB 2BFLA 4C1HA 2QDSA 5LCFA 2I7XA 1YCGA 4Z5YA 3PY6A 2FU9A 3G1PA 4ZO3A 3WXCA 3I14A 5A5ZA 3P2UA 4XWTA 3SD9A 3KNSA 1K07A 3AF6A 5ACSA 2YCBA 2FM6A 1DD6A 5AXOA 5AEBA 1ZTCA 2NXAA 4HKYA 3FCZA 3IEKA 4LE6A 1MQOA 4TZBA 5EV6A 3QH8A 5ACUA 4TZFA 2YNTB 2BFKA 5K4NA 3I15A 4AX1B 2XR1A 2QJSA 4D1TA 4BZ3A 2OHJA 2HB9A 1SMLA 3ADRA 4FEKA 2YZ3A 4HL1A 1YCHA 3MD7A 3RKJA 4H0DA 2OHIA 3ZNBA 2FU6A 1BC2A 1KR3A 1DDKA 4AWZA 2WRSA 4EYLA 4AWYB 4AX0B 5HIPA 5B3RA 4YSKA 3FAIA 5K4MA 2P97A 4DIKA 5A0TA 2WYMC 4C1EA 4YSBA 5K4KA 1ZKPA 2P1EA 2GKLA 4XUKA 2XF4A 4RM5A 4RL2A 5FQAA 5ACTA 3H3EA 3BV6A 1Y44A 2GFKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FU8 A;  4NQ2 A;  3AF5 A;  4D1W A;  1WRA A;  4D02 A;  3BK2 A;  3X2X A;  1X8G A;  5EHT A;  2Q0J A;  1X8I A;  2OHH A;  2AIO A;  2YNV A;  3JXP A;  4UBQ A;  2H6A A;  2ZZI A;  3ESH A;  4NQ4 A;  4C1F A;  5LLD A;  4F6Z A;  2Y87 A;  5AHO A;  2P18 A;  4D1V A;  4U4L A;  4BP0 A;  2M5D A;  2BR6 A;  5ACP A;  1WUO A;  2Y8A A;  4EYB A;  3IOF A;  1P9E A;  4EXY A;  4WD6 A;  1VJN A;  5EV8 A;  3PG4 A;  3ZWF A;  2YNV B;  2NZE A;  2GMN A;  2BGA A;  2FU7 A;  3SRX A;  5K0W A;  1VME A;  3IDZ A;  2FK6 A;  5EVK A;  5B15 A;  1A8T A;  4TYT A;  2GCU A;  3ZR9 A;  3DH8 A;  5A87 A;  5LE1 A;  1WUP A;  2NYP A;  4UAM A;  4J5F A;  2BTN A;  4O98 A;  4RAW A;  3AJ3 A;  2Q0I A;  3I0V A;  3SW3 A;  3T3O A;  2FHX A;  5LS3 A;  4EY2 A;  2M5C A;  4EXS A;  4NQ5 A;  5FQC A;  4UWS B;  4KEP A;  3KL7 A;  2ZO4 A;  1KO3 A;  2BC2 A;  2UYX A;  3DHA A;  5ACX A;  5IQK A;  2ZWR A;  2WHG A;  1HLK A;  2CBN A;  2QDT A;  4V0H A;  5EW0 A;  3RKK A;  2WYM A;  5HIQ A;  4PVT A;  1QH5 A;  4GYQ A;  5ACW A;  2BG8 A;  4ZO2 A;  4ZEJ A;  1ZNB A;  4XWW A;  3BC2 A;  4RAM A;  3SPU A;  1DXK A;  1VGN A;  2Q9U A;  2Q42 A;  3DHB A;  4GYU A;  5ACR A;  3X30 A;  4RL0 A;  5AYA A;  1YCF A;  1XM8 A;  5LCH A;  5EVB A;  3SBL A;  3L6N A;  5KIK A;  1WW1 A;  5KIL A;  2BG8 B;  2BIB A;  4FSB A;  2P4Z A;  3T3N A;  2AZ4 A;  1KO2 A;  4PVO A;  4Z5Z A;  5HIO A;  3F9O A;  4TZE A;  1A7T A;  3I11 A;  4AD9 A;  3X2Z A;  5AHR A;  4Z6X A;  2YNW A;  4FR7 A;  2BFZ A;  2I7V A;  5HH4 A;  4TZ9 A;  3DHC A;  5DPX A;  5HH5 A;  1XTO A;  4NQ6 A;  4KEQ A;  5HH6 A;  4J5H A;  3TP9 A;  1QH3 A;  4DIL A;  2YNT A;  2GFJ A;  3PY5 A;  4UWR B;  3LVZ A;  4GCW A;  3RPC A;  4TYF A;  3IEL A;  2QED A;  4F6H A;  4C1C A;  4C09 A;  2YNU A;  2BFZ B;  1JT1 A;  5LM6 A;  2NZF A;  3IE0 A;  2BG2 A;  4C1G A;  2VW8 A;  1E5D A;  2DKF A;  3S0Z A;  2R2D A;  2Y8B A;  4YSL A;  4EFZ A;  4CHL A;  4D1U A;  3I13 A;  4JO0 A;  2A7M A;  4ZNB A;  4RBS A;  1BVT A;  3IE1 A;  1M2X A;  5LSC A;  5EWA A;  2I7T A;  1BMC A;  4Z67 A;  2FHX B;  5HIS A;  3VPE A;  4C1D A;  3IOG A;  3A4Y A;  5B1U A;  4B87 A;  2DOO A;  3SFP A;  5ACQ A;  2BG7 A;  2WYL A;  3BK1 A;  3IEM A;  3Q6V A;  5ACV A;  3VQZ A;  4UA4 A;  3ZQ4 A;  1JJE A;  3X2Y A;  2ZNB A;  3R2U A;  2BG6 A;  3T9M A;  4HL2 A;  5EH9 A;  2E7Y A;  5EVD A;  4Z60 A;  5LMC A;  5AXR A;  1L9Y A;  3KNR A;  4UWP B;  5A0V A;  5LCA A;  2QIN A;  4P62 A;  3IE2 A;  1JJT A;  1X8H A;  2BMI A;  4Z7R A;  5FQB A;  4EYF A;  4UWO B;  2BFL A;  4C1H A;  2QDS A;  5LCF A;  2I7X A;  1YCG A;  4Z5Y A;  3PY6 A;  2FU9 A;  3G1P A;  4ZO3 A;  3WXC A;  3I14 A;  5A5Z A;  3P2U A;  4XWT A;  3SD9 A;  3KNS A;  1K07 A;  3AF6 A;  5ACS A;  2YCB A;  2FM6 A;  1DD6 A;  5AXO A;  5AEB A;  1ZTC A;  2NXA A;  4HKY A;  3FCZ A;  3IEK A;  4LE6 A;  1MQO A;  4TZB A;  5EV6 A;  3QH8 A;  5ACU A;  4TZF A;  2YNT B;  2BFK A;  5K4N A;  3I15 A;  4AX1 B;  2XR1 A;  2QJS A;  4D1T A;  4BZ3 A;  2OHJ A;  2HB9 A;  1SML A;  3ADR A;  4FEK A;  2YZ3 A;  4HL1 A;  1YCH A;  3MD7 A;  3RKJ A;  4H0D A;  2OHI A;  3ZNB A;  2FU6 A;  1BC2 A;  1KR3 A;  1DDK A;  4AWZ A;  2WRS A;  4EYL A;  4AWY B;  4AX0 B;  5HIP A;  5B3R A;  4YSK A;  3FAI A;  5K4M A;  2P97 A;  4DIK A;  5A0T A;  2WYM C;  4C1E A;  4YSB A;  5K4K A;  1ZKP A;  2P1E A;  2GKL A;  4XUK A;  2XF4 A;  4RM5 A;  4RL2 A;  5FQA A;  5ACT A;  3H3E A;  3BV6 A;  1Y44 A;  2GFK A; 
#chains in the Genus database with same CATH topology
 2FU8 A;  4NQ2 A;  3AF5 A;  4D1W A;  1WRA A;  4D02 A;  3BK2 A;  3X2X A;  1X8G A;  5EHT A;  2Q0J A;  1X8I A;  2OHH A;  2AIO A;  4AV7 A;  2YNV A;  3JXP A;  4UBQ A;  2H6A A;  2ZZI A;  3ESH A;  4NQ4 A;  4C1F A;  5LLD A;  4F6Z A;  2Y87 A;  5AHO A;  2P18 A;  4D1V A;  4U4L A;  4BP0 A;  2M5D A;  2BR6 A;  5ACP A;  1WUO A;  2Y8A A;  4EYB A;  3IOF A;  1P9E A;  4EXY A;  4WD6 A;  1VJN A;  5EV8 A;  3PG4 A;  3ZWF A;  2YHE A;  2YNV B;  2NZE A;  2GMN A;  2BGA A;  2FU7 A;  3SRX A;  5K0W A;  1VME A;  5A23 A;  3IDZ A;  2CG3 A;  2FK6 A;  5EVK A;  5B15 A;  1A8T A;  4TYT A;  2GCU A;  3ZR9 A;  3DH8 A;  5A87 A;  5LE1 A;  1WUP A;  2NYP A;  4UAM A;  4J5F A;  2BTN A;  4O98 A;  4RAW A;  3AJ3 A;  2Q0I A;  3I0V A;  3SW3 A;  3T3O A;  2FHX A;  5LS3 A;  4EY2 A;  2M5C A;  4EXS A;  4NQ5 A;  5FQC A;  4UWS B;  4KEP A;  3KL7 A;  2ZO4 A;  1KO3 A;  2BC2 A;  2UYX A;  3DHA A;  5ACX A;  5IQK A;  2ZWR A;  2WHG A;  1HLK A;  2CBN A;  2QDT A;  4V0H A;  5EW0 A;  3RKK A;  2WYM A;  5HIQ A;  4PVT A;  1QH5 A;  4GYQ A;  5ACW A;  2BG8 A;  4ZO2 A;  4ZEJ A;  1ZNB A;  4XWW A;  3BC2 A;  4RAM A;  3SPU A;  1DXK A;  1VGN A;  2Q9U A;  2Q42 A;  3DHB A;  4GYU A;  5ACR A;  3X30 A;  2CG2 A;  4RL0 A;  5AYA A;  1YCF A;  1XM8 A;  5LCH A;  5EVB A;  3SBL A;  3L6N A;  5KIK A;  1WW1 A;  5KIL A;  2BG8 B;  2BIB A;  4FSB A;  2P4Z A;  3T3N A;  2AZ4 A;  1KO2 A;  4PVO A;  4Z5Z A;  5HIO A;  5AJL A;  3F9O A;  4TZE A;  1A7T A;  3I11 A;  4AD9 A;  3X2Z A;  5AHR A;  4Z6X A;  2YNW A;  4FR7 A;  2BFZ A;  2I7V A;  5HH4 A;  4TZ9 A;  3DHC A;  5DPX A;  5HH5 A;  1XTO A;  4NQ6 A;  4KEQ A;  5HH6 A;  4AXH A;  4J5H A;  3TP9 A;  1QH3 A;  4DIL A;  2YNT A;  2GFJ A;  3PY5 A;  4UWR B;  3LVZ A;  4GCW A;  3RPC A;  4TYF A;  3IEL A;  2QED A;  4F6H A;  4C1C A;  4C09 A;  2YNU A;  2BFZ B;  1JT1 A;  5LM6 A;  2NZF A;  3IE0 A;  2BG2 A;  4C1G A;  2VW8 A;  1E5D A;  2DKF A;  3S0Z A;  2R2D A;  2Y8B A;  4YSL A;  4EFZ A;  4CHL A;  4D1U A;  3I13 A;  4JO0 A;  2A7M A;  4ZNB A;  4RBS A;  1BVT A;  3IE1 A;  1M2X A;  5LSC A;  4PDX A;  5EWA A;  2I7T A;  1BMC A;  4Z67 A;  2FHX B;  5HIS A;  3VPE A;  4C1D A;  3IOG A;  3A4Y A;  5B1U A;  4B87 A;  2DOO A;  3SFP A;  5ACQ A;  2BG7 A;  2WYL A;  3BK1 A;  3IEM A;  3Q6V A;  5ACV A;  2CFU A;  3VQZ A;  4UA4 A;  3ZQ4 A;  1JJE A;  3X2Y A;  2ZNB A;  3R2U A;  2BG6 A;  3T9M A;  4HL2 A;  5EH9 A;  2E7Y A;  5EVD A;  4Z60 A;  5LMC A;  5AXR A;  1L9Y A;  2CFZ A;  3KNR A;  4UWP B;  5A0V A;  5LCA A;  2QIN A;  4P62 A;  3IE2 A;  1JJT A;  1X8H A;  2BMI A;  4Z7R A;  5FQB A;  5AIJ A;  4EYF A;  4UWO B;  2BFL A;  4C1H A;  2QDS A;  5LCF A;  2I7X A;  1YCG A;  4Z5Y A;  3PY6 A;  2FU9 A;  3G1P A;  4ZO3 A;  3WXC A;  3I14 A;  5A5Z A;  3P2U A;  4XWT A;  3SD9 A;  3KNS A;  1K07 A;  3AF6 A;  5ACS A;  2YCB A;  2FM6 A;  1DD6 A;  5AXO A;  5AEB A;  1ZTC A;  2NXA A;  4HKY A;  3FCZ A;  3IEK A;  4LE6 A;  1MQO A;  4TZB A;  5EV6 A;  3QH8 A;  5ACU A;  4TZF A;  2YNT B;  2BFK A;  5K4N A;  3I15 A;  4AX1 B;  2XR1 A;  2QJS A;  4D1T A;  4BZ3 A;  2OHJ A;  2HB9 A;  1SML A;  3ADR A;  4FEK A;  2YZ3 A;  4HL1 A;  1YCH A;  3MD7 A;  3RKJ A;  4H0D A;  2OHI A;  3ZNB A;  2FU6 A;  1BC2 A;  1KR3 A;  1DDK A;  4AWZ A;  2WRS A;  4EYL A;  4AWY B;  4AX0 B;  5HIP A;  5B3R A;  4YSK A;  3FAI A;  5K4M A;  4NUR A;  2P97 A;  4DIK A;  5A0T A;  2WYM C;  4C1E A;  4YSB A;  5K4K A;  1ZKP A;  2P1E A;  2GKL A;  4XUK A;  2XF4 A;  4RM5 A;  4RL2 A;  5FQA A;  5ACT A;  3H3E A;  3BV6 A;  1Y44 A;  2GFK A; 
#chains in the Genus database with same CATH homology
 2FU8 A;  4NQ2 A;  3AF5 A;  4D1W A;  1WRA A;  4D02 A;  3BK2 A;  3X2X A;  1X8G A;  5EHT A;  2Q0J A;  1X8I A;  2OHH A;  2AIO A;  2YNV A;  3JXP A;  4UBQ A;  2H6A A;  2ZZI A;  3ESH A;  4NQ4 A;  4C1F A;  5LLD A;  4F6Z A;  2Y87 A;  5AHO A;  2P18 A;  4D1V A;  4U4L A;  4BP0 A;  2M5D A;  2BR6 A;  5ACP A;  1WUO A;  2Y8A A;  4EYB A;  3IOF A;  1P9E A;  4EXY A;  4WD6 A;  1VJN A;  5EV8 A;  3PG4 A;  3ZWF A;  2YNV B;  2NZE A;  2GMN A;  2BGA A;  2FU7 A;  3SRX A;  5K0W A;  1VME A;  3IDZ A;  2FK6 A;  5EVK A;  5B15 A;  1A8T A;  4TYT A;  2GCU A;  3ZR9 A;  3DH8 A;  5A87 A;  5LE1 A;  1WUP A;  2NYP A;  4UAM A;  4J5F A;  2BTN A;  4O98 A;  4RAW A;  3AJ3 A;  2Q0I A;  3I0V A;  3SW3 A;  3T3O A;  2FHX A;  5LS3 A;  4EY2 A;  2M5C A;  4EXS A;  4NQ5 A;  5FQC A;  4UWS B;  4KEP A;  3KL7 A;  2ZO4 A;  1KO3 A;  2BC2 A;  2UYX A;  3DHA A;  5ACX A;  5IQK A;  2ZWR A;  2WHG A;  1HLK A;  2CBN A;  2QDT A;  4V0H A;  5EW0 A;  3RKK A;  2WYM A;  5HIQ A;  4PVT A;  1QH5 A;  4GYQ A;  5ACW A;  2BG8 A;  4ZO2 A;  4ZEJ A;  1ZNB A;  4XWW A;  3BC2 A;  4RAM A;  3SPU A;  1DXK A;  1VGN A;  2Q9U A;  2Q42 A;  3DHB A;  4GYU A;  5ACR A;  3X30 A;  4RL0 A;  5AYA A;  1YCF A;  1XM8 A;  5LCH A;  5EVB A;  3SBL A;  3L6N A;  5KIK A;  1WW1 A;  5KIL A;  2BG8 B;  2BIB A;  4FSB A;  2P4Z A;  3T3N A;  2AZ4 A;  1KO2 A;  4PVO A;  4Z5Z A;  5HIO A;  3F9O A;  4TZE A;  1A7T A;  3I11 A;  4AD9 A;  3X2Z A;  5AHR A;  4Z6X A;  2YNW A;  4FR7 A;  2BFZ A;  2I7V A;  5HH4 A;  4TZ9 A;  3DHC A;  5DPX A;  5HH5 A;  1XTO A;  4NQ6 A;  4KEQ A;  5HH6 A;  4J5H A;  3TP9 A;  1QH3 A;  4DIL A;  2YNT A;  2GFJ A;  3PY5 A;  4UWR B;  3LVZ A;  4GCW A;  3RPC A;  4TYF A;  3IEL A;  2QED A;  4F6H A;  4C1C A;  4C09 A;  2YNU A;  2BFZ B;  1JT1 A;  5LM6 A;  2NZF A;  3IE0 A;  2BG2 A;  4C1G A;  2VW8 A;  1E5D A;  2DKF A;  3S0Z A;  2R2D A;  2Y8B A;  4YSL A;  4EFZ A;  4CHL A;  4D1U A;  3I13 A;  4JO0 A;  2A7M A;  4ZNB A;  4RBS A;  1BVT A;  3IE1 A;  1M2X A;  5LSC A;  5EWA A;  2I7T A;  1BMC A;  4Z67 A;  2FHX B;  5HIS A;  3VPE A;  4C1D A;  3IOG A;  3A4Y A;  5B1U A;  4B87 A;  2DOO A;  3SFP A;  5ACQ A;  2BG7 A;  2WYL A;  3BK1 A;  3IEM A;  3Q6V A;  5ACV A;  3VQZ A;  4UA4 A;  3ZQ4 A;  1JJE A;  3X2Y A;  2ZNB A;  3R2U A;  2BG6 A;  3T9M A;  4HL2 A;  5EH9 A;  2E7Y A;  5EVD A;  4Z60 A;  5LMC A;  5AXR A;  1L9Y A;  3KNR A;  4UWP B;  5A0V A;  5LCA A;  2QIN A;  4P62 A;  3IE2 A;  1JJT A;  1X8H A;  2BMI A;  4Z7R A;  5FQB A;  4EYF A;  4UWO B;  2BFL A;  4C1H A;  2QDS A;  5LCF A;  2I7X A;  1YCG A;  4Z5Y A;  3PY6 A;  2FU9 A;  3G1P A;  4ZO3 A;  3WXC A;  3I14 A;  5A5Z A;  3P2U A;  4XWT A;  3SD9 A;  3KNS A;  1K07 A;  3AF6 A;  5ACS A;  2YCB A;  2FM6 A;  1DD6 A;  5AXO A;  5AEB A;  1ZTC A;  2NXA A;  4HKY A;  3FCZ A;  3IEK A;  4LE6 A;  1MQO A;  4TZB A;  5EV6 A;  3QH8 A;  5ACU A;  4TZF A;  2YNT B;  2BFK A;  5K4N A;  3I15 A;  4AX1 B;  2XR1 A;  2QJS A;  4D1T A;  4BZ3 A;  2OHJ A;  2HB9 A;  1SML A;  3ADR A;  4FEK A;  2YZ3 A;  4HL1 A;  1YCH A;  3MD7 A;  3RKJ A;  4H0D A;  2OHI A;  3ZNB A;  2FU6 A;  1BC2 A;  1KR3 A;  1DDK A;  4AWZ A;  2WRS A;  4EYL A;  4AWY B;  4AX0 B;  5HIP A;  5B3R A;  4YSK A;  3FAI A;  5K4M A;  2P97 A;  4DIK A;  5A0T A;  2WYM C;  4C1E A;  4YSB A;  5K4K A;  1ZKP A;  2P1E A;  2GKL A;  4XUK A;  2XF4 A;  4RM5 A;  4RL2 A;  5FQA A;  5ACT A;  3H3E A;  3BV6 A;  1Y44 A;  2GFK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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