5ACVA

Vim-2-ox, discovery of novel inhibitor scaffolds against the metallo- beta-lactamase vim-2 by spr based fragment screening
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
233
structure length
232
Chain Sequence
GEYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNRS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords BETA-LACTAMASE
publication title Discovery of Novel Inhibitor Scaffolds Against the Metallo-Beta-Lactamase Vim-2 by Spr Based Fragment Screening
pubmed doi rcsb
source organism Pseudomonas aeruginosa
total genus 70
structure length 232
sequence length 233
chains with identical sequence B
ec nomenclature ec 3.5.2.6: Beta-lactamase.
pdb deposition date 2015-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5acvA00
5EVBA 3AF6A 2Y8AA 1KR3A 2NXAA 4DIKA 1XTOA 2YZ3A 5EWAA 4NQ4A 3ZNBA 4TYTA 4NQ5A 3VPEA 1WUOA 4RM5A 5LSCA 4TYFA 5HH6A 4ZNBA 3F9OA 3ZQ4A 2I7XA 2DKFA 5K4MA 1L9YA 4RBSA 5B1UA 4KEQA 2BIBA 4RL2A 4J5HA 3SFPA 1DXKA 1QH5A 1XM8A 1DD6A 1X8HA 2FHXB 4ZO3A 5K4KA 2ZO4A 2E7YA 3SPUA 4EFZA 2UYXA 3FAIA 4F6HA 5K0WA 2BFZB 2YNTA 5LCHA 2A7MA 3IELA 5LMCA 5EV6A 4Z6XA 1VMEA 4CHLA 2QDTA 1K07A 5LS3A 4EY2A 4UAMA 2BG8B 1QH3A 2BG2A 1BMCA 1WW1A 3LVZA 5ACSA 3I15A 3T3OA 5ACTA 3SW3A 1A7TA 2GKLA 4C1EA 4JO0A 1ZKPA 5LLDA 3PY6A 3ADRA 4B87A 4D1WA 3T9MA 4D02A 3I11A 2GCUA 5EW0A 1YCGA 2ZNBA 2QEDA 3QH8A 1ZNBA 3IEKA 5AYAA 5B3RA 3IE2A 4BZ3A 1E5DA 2OHJA 5ACXA 4EXYA 4C1DA 5KIKA 1DDKA 2DOOA 1HLKA 3SBLA 5A5ZA 4C09A 3AJ3A 3IE1A 5ACVA 3IEMA 1X8IA 4XWTA 2Q9UA 3P2UA 4DILA 3PG4A 2WRSA 4Z5YA 4PVTA 3FCZA 2YNVA 5EH9A 3DHBA 1JT1A 4TZEA 4EYFA 1VGNA 2WYLA 2Y87A 3DHAA 3X2ZA 4AX0B 4Z60A 1VJNA 3MD7A 2I7VA 2BR6A 5HH4A 5LCFA 3A4YA 4UWRB 2Y8BA 2XF4A 4C1GA 2BFZA 3DH8A 2QINA 5A0VA 3ZWFA 5AHOA 1YCHA 3X2YA 1KO3A 2P1EA 2WHGA 5FQCA 4HL2A 1M2XA 1P9EA 2Q0IA 2VW8A 3IE0A 3L6NA 4O98A 2BG8A 4D1VA 4RAMA 5LM6A 4UA4A 4D1TA 4C1HA 2AIOA 3Q6VA 2BFKA 5EV8A 2BG6A 2GFJA 5AXOA 5LE1A 2P4ZA 4AD9A 2BGAA 1YCFA 5AHRA 4RL0A 4EYBA 5A0TA 2FU8A 3I14A 2BTNA 2FU6A 4UWOB 5DPXA 4LE6A 3DHCA 2YNUA 2GMNA 5HH5A 3KNSA 4AWYB 3TP9A 3SRXA 1SMLA 4RAWA 2FM6A 1ZTCA 3BK1A 4P62A 5ACUA 2YNTB 3AF5A 2M5CA 5IQKA 4ZEJA 4WD6A 3RKJA 1JJTA 5AXRA 1BVTA 2R2DA 4TZBA 5ACPA 5A87A 4NQ6A 2NYPA 2OHHA 5EVKA 5FQBA 4KEPA 3IDZA 4BP0A 1KO2A 5K4NA 4U4LA 2M5DA 4TZFA 2FU7A 2XR1A 2P97A 2QDSA 1Y44A 5ACWA 2H6AA 3G1PA 4GYQA 3I13A 2FHXA 5ACRA 4C1FA 4XWWA 5B15A 3X2XA 1BC2A 4FR7A 3VQZA 2I7TA 4D1UA 2FK6A 3BC2A 2YNWA 2BG7A 1MQOA 3H3EA 5AEBA 3IOFA 4F6ZA 3ZR9A 2YNVB 4EYLA 2BFLA 5HIPA 4NQ2A 4H0DA 3IOGA 1X8GA 4UWSB 2NZFA 2HB9A 3RKKA 3R2UA 3ESHA 2YCBA 3JXPA 3WXCA 5HISA 2WYMA 4UWPB 3I0VA 1WRAA 2AZ4A 4UBQA 2WYMC 2FU9A 3PY5A 4FSBA 2CBNA 4YSKA 4EXSA 2GFKA 1WUPA 4AWZA 4ZO2A 4HKYA 4J5FA 2P18A 4AX1B 4GYUA 4C1CA 4YSBA 5HIQA 4GCWA 5FQAA 3BV6A 5HIOA 4YSLA 4XUKA 2BMIA 5EHTA 3BK2A 3X30A 2Q0JA 2BC2A 2OHIA 5EVDA 2NZEA 1JJEA 4Z67A 1A8TA 3RPCA 3S0ZA 2Q42A 5ACQA 3T3NA 3KL7A 4Z7RA 2QJSA 4FEKA 4PVOA 4TZ9A 2ZWRA 4V0HA 2ZZIA 4HL1A 4Z5ZA 5LCAA 5KILA 3KNRA 3SD9A
chains in the Genus database with same CATH superfamily
5EVBA 3AF6A 2Y8AA 1KR3A 2NXAA 4DIKA 1XTOA 2YZ3A 5EWAA 4NQ4A 3ZNBA 4TYTA 4NQ5A 3VPEA 1WUOA 4RM5A 5LSCA 4TYFA 5HH6A 4ZNBA 3F9OA 3ZQ4A 2I7XA 2DKFA 5K4MA 1L9YA 4RBSA 5B1UA 4KEQA 2BIBA 4RL2A 4J5HA 3SFPA 1DXKA 1QH5A 1XM8A 1DD6A 1X8HA 2FHXB 4ZO3A 5K4KA 2ZO4A 2E7YA 3SPUA 4EFZA 2UYXA 3FAIA 4F6HA 5K0WA 2BFZB 2YNTA 5LCHA 2A7MA 3IELA 5LMCA 5EV6A 4Z6XA 1VMEA 4CHLA 2QDTA 1K07A 5LS3A 4EY2A 4UAMA 2BG8B 1QH3A 2BG2A 1BMCA 1WW1A 3LVZA 5ACSA 4NURA 3I15A 3T3OA 5ACTA 3SW3A 1A7TA 2GKLA 4C1EA 4JO0A 1ZKPA 5LLDA 3PY6A 3ADRA 4B87A 4D1WA 3T9MA 4D02A 3I11A 2GCUA 5EW0A 1YCGA 2ZNBA 2QEDA 3QH8A 1ZNBA 3IEKA 5AYAA 5B3RA 3IE2A 4BZ3A 1E5DA 5AIJA 2OHJA 5ACXA 4EXYA 4C1DA 5KIKA 1DDKA 2DOOA 1HLKA 3SBLA 5A5ZA 4C09A 3AJ3A 3IE1A 5ACVA 3IEMA 1X8IA 2CFUA 4XWTA 2Q9UA 3P2UA 4DILA 3PG4A 2WRSA 4Z5YA 4PVTA 3FCZA 2YNVA 5EH9A 3DHBA 1JT1A 4TZEA 4EYFA 1VGNA 2WYLA 2Y87A 3DHAA 3X2ZA 4AX0B 4Z60A 1VJNA 3MD7A 2I7VA 2BR6A 5HH4A 5LCFA 3A4YA 4UWRB 2Y8BA 2XF4A 4C1GA 2BFZA 3DH8A 2QINA 5A0VA 3ZWFA 5AHOA 1YCHA 3X2YA 2YHEA 4AXHA 1KO3A 2P1EA 2WHGA 5FQCA 4HL2A 1M2XA 1P9EA 2Q0IA 2VW8A 3IE0A 3L6NA 4O98A 2BG8A 4D1VA 4RAMA 5LM6A 4UA4A 4D1TA 4C1HA 2AIOA 3Q6VA 2BFKA 5EV8A 2BG6A 2GFJA 5AXOA 5LE1A 2P4ZA 4AD9A 2CFZA 2BGAA 1YCFA 5AHRA 4RL0A 4EYBA 5A0TA 2FU8A 3I14A 4PDXA 2BTNA 2FU6A 4UWOB 5DPXA 4LE6A 3DHCA 2YNUA 2GMNA 5HH5A 3KNSA 4AWYB 3TP9A 3SRXA 1SMLA 4RAWA 2FM6A 5AJLA 1ZTCA 3BK1A 4P62A 5ACUA 2YNTB 3AF5A 2M5CA 5IQKA 4ZEJA 4WD6A 3RKJA 1JJTA 5AXRA 1BVTA 2R2DA 4TZBA 5ACPA 5A87A 4NQ6A 4AV7A 2NYPA 2OHHA 5EVKA 5FQBA 4KEPA 3IDZA 4BP0A 1KO2A 5K4NA 4U4LA 2M5DA 4TZFA 2FU7A 2XR1A 2P97A 2QDSA 1Y44A 5ACWA 2H6AA 3G1PA 4GYQA 3I13A 2FHXA 5ACRA 2CG3A 4C1FA 4XWWA 5B15A 3X2XA 1BC2A 4FR7A 3VQZA 2I7TA 4D1UA 2FK6A 3BC2A 2YNWA 2BG7A 1MQOA 2CG2A 3H3EA 5AEBA 3IOFA 4F6ZA 3ZR9A 2YNVB 4EYLA 2BFLA 5HIPA 4NQ2A 4H0DA 3IOGA 1X8GA 4UWSB 2NZFA 2HB9A 3RKKA 3R2UA 3ESHA 2YCBA 3JXPA 3WXCA 5HISA 2WYMA 4UWPB 3I0VA 1WRAA 2AZ4A 4UBQA 2WYMC 2FU9A 3PY5A 4FSBA 2CBNA 4YSKA 4EXSA 2GFKA 1WUPA 4AWZA 4ZO2A 5A23A 4HKYA 4J5FA 2P18A 4AX1B 4GYUA 4C1CA 4YSBA 5HIQA 4GCWA 5FQAA 3BV6A 5HIOA 4YSLA 4XUKA 2BMIA 5EHTA 3BK2A 3X30A 2Q0JA 2BC2A 2OHIA 5EVDA 2NZEA 1JJEA 4Z67A 1A8TA 3RPCA 3S0ZA 2Q42A 5ACQA 3T3NA 3KL7A 4Z7RA 2QJSA 4FEKA 4PVOA 4TZ9A 2ZWRA 4V0HA 2ZZIA 4HL1A 4Z5ZA 5LCAA 5KILA 3KNRA 3SD9A
chains in the Genus database with same CATH topology
5EVBA 3AF6A 2Y8AA 1KR3A 2NXAA 4DIKA 1XTOA 2YZ3A 5EWAA 4NQ4A 3ZNBA 4TYTA 4NQ5A 3VPEA 1WUOA 4RM5A 5LSCA 4TYFA 5HH6A 4ZNBA 3F9OA 3ZQ4A 2I7XA 2DKFA 5K4MA 1L9YA 4RBSA 5B1UA 4KEQA 2BIBA 4RL2A 4J5HA 3SFPA 1DXKA 1QH5A 1XM8A 1DD6A 1X8HA 2FHXB 4ZO3A 5K4KA 2ZO4A 2E7YA 3SPUA 4EFZA 2UYXA 3FAIA 4F6HA 5K0WA 2BFZB 2YNTA 5LCHA 2A7MA 3IELA 5LMCA 5EV6A 4Z6XA 1VMEA 4CHLA 2QDTA 1K07A 5LS3A 4EY2A 4UAMA 2BG8B 1QH3A 2BG2A 1BMCA 1WW1A 3LVZA 5ACSA 3I15A 3T3OA 5ACTA 3SW3A 1A7TA 2GKLA 4C1EA 4JO0A 1ZKPA 5LLDA 3PY6A 3ADRA 4B87A 4D1WA 3T9MA 4D02A 3I11A 2GCUA 5EW0A 1YCGA 2ZNBA 2QEDA 3QH8A 1ZNBA 3IEKA 5AYAA 5B3RA 3IE2A 4BZ3A 1E5DA 2OHJA 5ACXA 4EXYA 4C1DA 5KIKA 1DDKA 2DOOA 1HLKA 3SBLA 5A5ZA 4C09A 3AJ3A 3IE1A 5ACVA 3IEMA 1X8IA 4XWTA 2Q9UA 3P2UA 4DILA 3PG4A 2WRSA 4Z5YA 4PVTA 3FCZA 2YNVA 5EH9A 3DHBA 1JT1A 4TZEA 4EYFA 1VGNA 2WYLA 2Y87A 3DHAA 3X2ZA 4AX0B 4Z60A 1VJNA 3MD7A 2I7VA 2BR6A 5HH4A 5LCFA 3A4YA 4UWRB 2Y8BA 2XF4A 4C1GA 2BFZA 3DH8A 2QINA 5A0VA 3ZWFA 5AHOA 1YCHA 3X2YA 1KO3A 2P1EA 2WHGA 5FQCA 4HL2A 1M2XA 1P9EA 2Q0IA 2VW8A 3IE0A 3L6NA 4O98A 2BG8A 4D1VA 4RAMA 5LM6A 4UA4A 4D1TA 4C1HA 2AIOA 3Q6VA 2BFKA 5EV8A 2BG6A 2GFJA 5AXOA 5LE1A 2P4ZA 4AD9A 2BGAA 1YCFA 5AHRA 4RL0A 4EYBA 5A0TA 2FU8A 3I14A 2BTNA 2FU6A 4UWOB 5DPXA 4LE6A 3DHCA 2YNUA 2GMNA 5HH5A 3KNSA 4AWYB 3TP9A 3SRXA 1SMLA 4RAWA 2FM6A 1ZTCA 3BK1A 4P62A 5ACUA 2YNTB 3AF5A 2M5CA 5IQKA 4ZEJA 4WD6A 3RKJA 1JJTA 5AXRA 1BVTA 2R2DA 4TZBA 5ACPA 5A87A 4NQ6A 2NYPA 2OHHA 5EVKA 5FQBA 4KEPA 3IDZA 4BP0A 1KO2A 5K4NA 4U4LA 2M5DA 4TZFA 2FU7A 2XR1A 2P97A 2QDSA 1Y44A 5ACWA 2H6AA 3G1PA 4GYQA 3I13A 2FHXA 5ACRA 4C1FA 4XWWA 5B15A 3X2XA 1BC2A 4FR7A 3VQZA 2I7TA 4D1UA 2FK6A 3BC2A 2YNWA 2BG7A 1MQOA 3H3EA 5AEBA 3IOFA 4F6ZA 3ZR9A 2YNVB 4EYLA 2BFLA 5HIPA 4NQ2A 4H0DA 3IOGA 1X8GA 4UWSB 2NZFA 2HB9A 3RKKA 3R2UA 3ESHA 2YCBA 3JXPA 3WXCA 5HISA 2WYMA 4UWPB 3I0VA 1WRAA 2AZ4A 4UBQA 2WYMC 2FU9A 3PY5A 4FSBA 2CBNA 4YSKA 4EXSA 2GFKA 1WUPA 4AWZA 4ZO2A 4HKYA 4J5FA 2P18A 4AX1B 4GYUA 4C1CA 4YSBA 5HIQA 4GCWA 5FQAA 3BV6A 5HIOA 4YSLA 4XUKA 2BMIA 5EHTA 3BK2A 3X30A 2Q0JA 2BC2A 2OHIA 5EVDA 2NZEA 1JJEA 4Z67A 1A8TA 3RPCA 3S0ZA 2Q42A 5ACQA 3T3NA 3KL7A 4Z7RA 2QJSA 4FEKA 4PVOA 4TZ9A 2ZWRA 4V0HA 2ZZIA 4HL1A 4Z5ZA 5LCAA 5KILA 3KNRA 3SD9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5EVB A;  3AF6 A;  2Y8A A;  1KR3 A;  2NXA A;  4DIK A;  1XTO A;  2YZ3 A;  5EWA A;  4NQ4 A;  3ZNB A;  4TYT A;  4NQ5 A;  3VPE A;  1WUO A;  4RM5 A;  5LSC A;  4TYF A;  5HH6 A;  4ZNB A;  3F9O A;  3ZQ4 A;  2I7X A;  2DKF A;  5K4M A;  1L9Y A;  4RBS A;  5B1U A;  4KEQ A;  2BIB A;  4RL2 A;  4J5H A;  3SFP A;  1DXK A;  1QH5 A;  1XM8 A;  1DD6 A;  1X8H A;  2FHX B;  4ZO3 A;  5K4K A;  2ZO4 A;  2E7Y A;  3SPU A;  4EFZ A;  2UYX A;  3FAI A;  4F6H A;  5K0W A;  2BFZ B;  2YNT A;  5LCH A;  2A7M A;  3IEL A;  5LMC A;  5EV6 A;  4Z6X A;  1VME A;  4CHL A;  2QDT A;  1K07 A;  5LS3 A;  4EY2 A;  4UAM A;  2BG8 B;  1QH3 A;  2BG2 A;  1BMC A;  1WW1 A;  3LVZ A;  5ACS A;  3I15 A;  3T3O A;  5ACT A;  3SW3 A;  1A7T A;  2GKL A;  4C1E A;  4JO0 A;  1ZKP A;  5LLD A;  3PY6 A;  3ADR A;  4B87 A;  4D1W A;  3T9M A;  4D02 A;  3I11 A;  2GCU A;  5EW0 A;  1YCG A;  2ZNB A;  2QED A;  3QH8 A;  1ZNB A;  3IEK A;  5AYA A;  5B3R A;  3IE2 A;  4BZ3 A;  1E5D A;  2OHJ A;  5ACX A;  4EXY A;  4C1D A;  5KIK A;  1DDK A;  2DOO A;  1HLK A;  3SBL A;  5A5Z A;  4C09 A;  3AJ3 A;  3IE1 A;  5ACV A;  3IEM A;  1X8I A;  4XWT A;  2Q9U A;  3P2U A;  4DIL A;  3PG4 A;  2WRS A;  4Z5Y A;  4PVT A;  3FCZ A;  2YNV A;  5EH9 A;  3DHB A;  1JT1 A;  4TZE A;  4EYF A;  1VGN A;  2WYL A;  2Y87 A;  3DHA A;  3X2Z A;  4AX0 B;  4Z60 A;  1VJN A;  3MD7 A;  2I7V A;  2BR6 A;  5HH4 A;  5LCF A;  3A4Y A;  4UWR B;  2Y8B A;  2XF4 A;  4C1G A;  2BFZ A;  3DH8 A;  2QIN A;  5A0V A;  3ZWF A;  5AHO A;  1YCH A;  3X2Y A;  1KO3 A;  2P1E A;  2WHG A;  5FQC A;  4HL2 A;  1M2X A;  1P9E A;  2Q0I A;  2VW8 A;  3IE0 A;  3L6N A;  4O98 A;  2BG8 A;  4D1V A;  4RAM A;  5LM6 A;  4UA4 A;  4D1T A;  4C1H A;  2AIO A;  3Q6V A;  2BFK A;  5EV8 A;  2BG6 A;  2GFJ A;  5AXO A;  5LE1 A;  2P4Z A;  4AD9 A;  2BGA A;  1YCF A;  5AHR A;  4RL0 A;  4EYB A;  5A0T A;  2FU8 A;  3I14 A;  2BTN A;  2FU6 A;  4UWO B;  5DPX A;  4LE6 A;  3DHC A;  2YNU A;  2GMN A;  5HH5 A;  3KNS A;  4AWY B;  3TP9 A;  3SRX A;  1SML A;  4RAW A;  2FM6 A;  1ZTC A;  3BK1 A;  4P62 A;  5ACU A;  2YNT B;  3AF5 A;  2M5C A;  5IQK A;  4ZEJ A;  4WD6 A;  3RKJ A;  1JJT A;  5AXR A;  1BVT A;  2R2D A;  4TZB A;  5ACP A;  5A87 A;  4NQ6 A;  2NYP A;  2OHH A;  5EVK A;  5FQB A;  4KEP A;  3IDZ A;  4BP0 A;  1KO2 A;  5K4N A;  4U4L A;  2M5D A;  4TZF A;  2FU7 A;  2XR1 A;  2P97 A;  2QDS A;  1Y44 A;  5ACW A;  2H6A A;  3G1P A;  4GYQ A;  3I13 A;  2FHX A;  5ACR A;  4C1F A;  4XWW A;  5B15 A;  3X2X A;  1BC2 A;  4FR7 A;  3VQZ A;  2I7T A;  4D1U A;  2FK6 A;  3BC2 A;  2YNW A;  2BG7 A;  1MQO A;  3H3E A;  5AEB A;  3IOF A;  4F6Z A;  3ZR9 A;  2YNV B;  4EYL A;  2BFL A;  5HIP A;  4NQ2 A;  4H0D A;  3IOG A;  1X8G A;  4UWS B;  2NZF A;  2HB9 A;  3RKK A;  3R2U A;  3ESH A;  2YCB A;  3JXP A;  3WXC A;  5HIS A;  2WYM A;  4UWP B;  3I0V A;  1WRA A;  2AZ4 A;  4UBQ A;  2WYM C;  2FU9 A;  3PY5 A;  4FSB A;  2CBN A;  4YSK A;  4EXS A;  2GFK A;  1WUP A;  4AWZ A;  4ZO2 A;  4HKY A;  4J5F A;  2P18 A;  4AX1 B;  4GYU A;  4C1C A;  4YSB A;  5HIQ A;  4GCW A;  5FQA A;  3BV6 A;  5HIO A;  4YSL A;  4XUK A;  2BMI A;  5EHT A;  3BK2 A;  3X30 A;  2Q0J A;  2BC2 A;  2OHI A;  5EVD A;  2NZE A;  1JJE A;  4Z67 A;  1A8T A;  3RPC A;  3S0Z A;  2Q42 A;  5ACQ A;  3T3N A;  3KL7 A;  4Z7R A;  2QJS A;  4FEK A;  4PVO A;  4TZ9 A;  2ZWR A;  4V0H A;  2ZZI A;  4HL1 A;  4Z5Z A;  5LCA A;  5KIL A;  3KNR A;  3SD9 A; 
#chains in the Genus database with same CATH topology
 5EVB A;  3AF6 A;  2Y8A A;  1KR3 A;  2NXA A;  4DIK A;  1XTO A;  2YZ3 A;  5EWA A;  4NQ4 A;  3ZNB A;  4TYT A;  4NQ5 A;  3VPE A;  1WUO A;  4RM5 A;  5LSC A;  4TYF A;  5HH6 A;  4ZNB A;  3F9O A;  3ZQ4 A;  2I7X A;  2DKF A;  5K4M A;  1L9Y A;  4RBS A;  5B1U A;  4KEQ A;  2BIB A;  4RL2 A;  4J5H A;  3SFP A;  1DXK A;  1QH5 A;  1XM8 A;  1DD6 A;  1X8H A;  2FHX B;  4ZO3 A;  5K4K A;  2ZO4 A;  2E7Y A;  3SPU A;  4EFZ A;  2UYX A;  3FAI A;  4F6H A;  5K0W A;  2BFZ B;  2YNT A;  5LCH A;  2A7M A;  3IEL A;  5LMC A;  5EV6 A;  4Z6X A;  1VME A;  4CHL A;  2QDT A;  1K07 A;  5LS3 A;  4EY2 A;  4UAM A;  2BG8 B;  1QH3 A;  2BG2 A;  1BMC A;  1WW1 A;  3LVZ A;  5ACS A;  4NUR A;  3I15 A;  3T3O A;  5ACT A;  3SW3 A;  1A7T A;  2GKL A;  4C1E A;  4JO0 A;  1ZKP A;  5LLD A;  3PY6 A;  3ADR A;  4B87 A;  4D1W A;  3T9M A;  4D02 A;  3I11 A;  2GCU A;  5EW0 A;  1YCG A;  2ZNB A;  2QED A;  3QH8 A;  1ZNB A;  3IEK A;  5AYA A;  5B3R A;  3IE2 A;  4BZ3 A;  1E5D A;  5AIJ A;  2OHJ A;  5ACX A;  4EXY A;  4C1D A;  5KIK A;  1DDK A;  2DOO A;  1HLK A;  3SBL A;  5A5Z A;  4C09 A;  3AJ3 A;  3IE1 A;  5ACV A;  3IEM A;  1X8I A;  2CFU A;  4XWT A;  2Q9U A;  3P2U A;  4DIL A;  3PG4 A;  2WRS A;  4Z5Y A;  4PVT A;  3FCZ A;  2YNV A;  5EH9 A;  3DHB A;  1JT1 A;  4TZE A;  4EYF A;  1VGN A;  2WYL A;  2Y87 A;  3DHA A;  3X2Z A;  4AX0 B;  4Z60 A;  1VJN A;  3MD7 A;  2I7V A;  2BR6 A;  5HH4 A;  5LCF A;  3A4Y A;  4UWR B;  2Y8B A;  2XF4 A;  4C1G A;  2BFZ A;  3DH8 A;  2QIN A;  5A0V A;  3ZWF A;  5AHO A;  1YCH A;  3X2Y A;  2YHE A;  4AXH A;  1KO3 A;  2P1E A;  2WHG A;  5FQC A;  4HL2 A;  1M2X A;  1P9E A;  2Q0I A;  2VW8 A;  3IE0 A;  3L6N A;  4O98 A;  2BG8 A;  4D1V A;  4RAM A;  5LM6 A;  4UA4 A;  4D1T A;  4C1H A;  2AIO A;  3Q6V A;  2BFK A;  5EV8 A;  2BG6 A;  2GFJ A;  5AXO A;  5LE1 A;  2P4Z A;  4AD9 A;  2CFZ A;  2BGA A;  1YCF A;  5AHR A;  4RL0 A;  4EYB A;  5A0T A;  2FU8 A;  3I14 A;  4PDX A;  2BTN A;  2FU6 A;  4UWO B;  5DPX A;  4LE6 A;  3DHC A;  2YNU A;  2GMN A;  5HH5 A;  3KNS A;  4AWY B;  3TP9 A;  3SRX A;  1SML A;  4RAW A;  2FM6 A;  5AJL A;  1ZTC A;  3BK1 A;  4P62 A;  5ACU A;  2YNT B;  3AF5 A;  2M5C A;  5IQK A;  4ZEJ A;  4WD6 A;  3RKJ A;  1JJT A;  5AXR A;  1BVT A;  2R2D A;  4TZB A;  5ACP A;  5A87 A;  4NQ6 A;  4AV7 A;  2NYP A;  2OHH A;  5EVK A;  5FQB A;  4KEP A;  3IDZ A;  4BP0 A;  1KO2 A;  5K4N A;  4U4L A;  2M5D A;  4TZF A;  2FU7 A;  2XR1 A;  2P97 A;  2QDS A;  1Y44 A;  5ACW A;  2H6A A;  3G1P A;  4GYQ A;  3I13 A;  2FHX A;  5ACR A;  2CG3 A;  4C1F A;  4XWW A;  5B15 A;  3X2X A;  1BC2 A;  4FR7 A;  3VQZ A;  2I7T A;  4D1U A;  2FK6 A;  3BC2 A;  2YNW A;  2BG7 A;  1MQO A;  2CG2 A;  3H3E A;  5AEB A;  3IOF A;  4F6Z A;  3ZR9 A;  2YNV B;  4EYL A;  2BFL A;  5HIP A;  4NQ2 A;  4H0D A;  3IOG A;  1X8G A;  4UWS B;  2NZF A;  2HB9 A;  3RKK A;  3R2U A;  3ESH A;  2YCB A;  3JXP A;  3WXC A;  5HIS A;  2WYM A;  4UWP B;  3I0V A;  1WRA A;  2AZ4 A;  4UBQ A;  2WYM C;  2FU9 A;  3PY5 A;  4FSB A;  2CBN A;  4YSK A;  4EXS A;  2GFK A;  1WUP A;  4AWZ A;  4ZO2 A;  5A23 A;  4HKY A;  4J5F A;  2P18 A;  4AX1 B;  4GYU A;  4C1C A;  4YSB A;  5HIQ A;  4GCW A;  5FQA A;  3BV6 A;  5HIO A;  4YSL A;  4XUK A;  2BMI A;  5EHT A;  3BK2 A;  3X30 A;  2Q0J A;  2BC2 A;  2OHI A;  5EVD A;  2NZE A;  1JJE A;  4Z67 A;  1A8T A;  3RPC A;  3S0Z A;  2Q42 A;  5ACQ A;  3T3N A;  3KL7 A;  4Z7R A;  2QJS A;  4FEK A;  4PVO A;  4TZ9 A;  2ZWR A;  4V0H A;  2ZZI A;  4HL1 A;  4Z5Z A;  5LCA A;  5KIL A;  3KNR A;  3SD9 A; 
#chains in the Genus database with same CATH homology
 5EVB A;  3AF6 A;  2Y8A A;  1KR3 A;  2NXA A;  4DIK A;  1XTO A;  2YZ3 A;  5EWA A;  4NQ4 A;  3ZNB A;  4TYT A;  4NQ5 A;  3VPE A;  1WUO A;  4RM5 A;  5LSC A;  4TYF A;  5HH6 A;  4ZNB A;  3F9O A;  3ZQ4 A;  2I7X A;  2DKF A;  5K4M A;  1L9Y A;  4RBS A;  5B1U A;  4KEQ A;  2BIB A;  4RL2 A;  4J5H A;  3SFP A;  1DXK A;  1QH5 A;  1XM8 A;  1DD6 A;  1X8H A;  2FHX B;  4ZO3 A;  5K4K A;  2ZO4 A;  2E7Y A;  3SPU A;  4EFZ A;  2UYX A;  3FAI A;  4F6H A;  5K0W A;  2BFZ B;  2YNT A;  5LCH A;  2A7M A;  3IEL A;  5LMC A;  5EV6 A;  4Z6X A;  1VME A;  4CHL A;  2QDT A;  1K07 A;  5LS3 A;  4EY2 A;  4UAM A;  2BG8 B;  1QH3 A;  2BG2 A;  1BMC A;  1WW1 A;  3LVZ A;  5ACS A;  3I15 A;  3T3O A;  5ACT A;  3SW3 A;  1A7T A;  2GKL A;  4C1E A;  4JO0 A;  1ZKP A;  5LLD A;  3PY6 A;  3ADR A;  4B87 A;  4D1W A;  3T9M A;  4D02 A;  3I11 A;  2GCU A;  5EW0 A;  1YCG A;  2ZNB A;  2QED A;  3QH8 A;  1ZNB A;  3IEK A;  5AYA A;  5B3R A;  3IE2 A;  4BZ3 A;  1E5D A;  2OHJ A;  5ACX A;  4EXY A;  4C1D A;  5KIK A;  1DDK A;  2DOO A;  1HLK A;  3SBL A;  5A5Z A;  4C09 A;  3AJ3 A;  3IE1 A;  5ACV A;  3IEM A;  1X8I A;  4XWT A;  2Q9U A;  3P2U A;  4DIL A;  3PG4 A;  2WRS A;  4Z5Y A;  4PVT A;  3FCZ A;  2YNV A;  5EH9 A;  3DHB A;  1JT1 A;  4TZE A;  4EYF A;  1VGN A;  2WYL A;  2Y87 A;  3DHA A;  3X2Z A;  4AX0 B;  4Z60 A;  1VJN A;  3MD7 A;  2I7V A;  2BR6 A;  5HH4 A;  5LCF A;  3A4Y A;  4UWR B;  2Y8B A;  2XF4 A;  4C1G A;  2BFZ A;  3DH8 A;  2QIN A;  5A0V A;  3ZWF A;  5AHO A;  1YCH A;  3X2Y A;  1KO3 A;  2P1E A;  2WHG A;  5FQC A;  4HL2 A;  1M2X A;  1P9E A;  2Q0I A;  2VW8 A;  3IE0 A;  3L6N A;  4O98 A;  2BG8 A;  4D1V A;  4RAM A;  5LM6 A;  4UA4 A;  4D1T A;  4C1H A;  2AIO A;  3Q6V A;  2BFK A;  5EV8 A;  2BG6 A;  2GFJ A;  5AXO A;  5LE1 A;  2P4Z A;  4AD9 A;  2BGA A;  1YCF A;  5AHR A;  4RL0 A;  4EYB A;  5A0T A;  2FU8 A;  3I14 A;  2BTN A;  2FU6 A;  4UWO B;  5DPX A;  4LE6 A;  3DHC A;  2YNU A;  2GMN A;  5HH5 A;  3KNS A;  4AWY B;  3TP9 A;  3SRX A;  1SML A;  4RAW A;  2FM6 A;  1ZTC A;  3BK1 A;  4P62 A;  5ACU A;  2YNT B;  3AF5 A;  2M5C A;  5IQK A;  4ZEJ A;  4WD6 A;  3RKJ A;  1JJT A;  5AXR A;  1BVT A;  2R2D A;  4TZB A;  5ACP A;  5A87 A;  4NQ6 A;  2NYP A;  2OHH A;  5EVK A;  5FQB A;  4KEP A;  3IDZ A;  4BP0 A;  1KO2 A;  5K4N A;  4U4L A;  2M5D A;  4TZF A;  2FU7 A;  2XR1 A;  2P97 A;  2QDS A;  1Y44 A;  5ACW A;  2H6A A;  3G1P A;  4GYQ A;  3I13 A;  2FHX A;  5ACR A;  4C1F A;  4XWW A;  5B15 A;  3X2X A;  1BC2 A;  4FR7 A;  3VQZ A;  2I7T A;  4D1U A;  2FK6 A;  3BC2 A;  2YNW A;  2BG7 A;  1MQO A;  3H3E A;  5AEB A;  3IOF A;  4F6Z A;  3ZR9 A;  2YNV B;  4EYL A;  2BFL A;  5HIP A;  4NQ2 A;  4H0D A;  3IOG A;  1X8G A;  4UWS B;  2NZF A;  2HB9 A;  3RKK A;  3R2U A;  3ESH A;  2YCB A;  3JXP A;  3WXC A;  5HIS A;  2WYM A;  4UWP B;  3I0V A;  1WRA A;  2AZ4 A;  4UBQ A;  2WYM C;  2FU9 A;  3PY5 A;  4FSB A;  2CBN A;  4YSK A;  4EXS A;  2GFK A;  1WUP A;  4AWZ A;  4ZO2 A;  4HKY A;  4J5F A;  2P18 A;  4AX1 B;  4GYU A;  4C1C A;  4YSB A;  5HIQ A;  4GCW A;  5FQA A;  3BV6 A;  5HIO A;  4YSL A;  4XUK A;  2BMI A;  5EHT A;  3BK2 A;  3X30 A;  2Q0J A;  2BC2 A;  2OHI A;  5EVD A;  2NZE A;  1JJE A;  4Z67 A;  1A8T A;  3RPC A;  3S0Z A;  2Q42 A;  5ACQ A;  3T3N A;  3KL7 A;  4Z7R A;  2QJS A;  4FEK A;  4PVO A;  4TZ9 A;  2ZWR A;  4V0H A;  2ZZI A;  4HL1 A;  4Z5Z A;  5LCA A;  5KIL A;  3KNR A;  3SD9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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