5K4MA

Directed evolutionary changes in mbl super family - ndm-1 round 10 crystal-3
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
228
structure length
228
Chain Sequence
b'DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Metallo-beta-lactamase type 2
publication title Enzyme evolvability is contingent on the initial sequence background
rcsb
source organism Klebsiella pneumoniae
molecule tags Hydrolase
total genus 73
structure length 228
sequence length 228
ec nomenclature ec 3.5.2.6: Beta-lactamase.
pdb deposition date 2016-05-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5k4mA00
3FAIA 2FU9A 2DKFA 4F6ZA 4J5FA 2NYPA 4EFZA 1DDKA 2BFZA 3IDZA 4GCWA 4GYQA 4ZNBA 4RL2A 2Q0JA 2ZWRA 4NQ5A 4EYLA 4D1WA 4Z5YA 2FHXB 3DHCA 2WYMC 2XF4A 1VMEA 2BG2A 4KEPA 3RKKA 3X2ZA 4DIKA 2NZFA 3AF6A 2I7XA 4DILA 1JT1A 3L6NA 2FU8A 3AF5A 4EXSA 5ACVA 1L9YA 3I11A 5IQKA 1Y44A 2GKLA 1DD6A 4KEQA 3WXCA 3RPCA 1M2XA 2A7MA 3ZQ4A 2CBNA 1ZNBA 2M5CA 5HISA 5LCHA 4YSKA 4BP0A 1VJNA 5DPXA 2YNTA 3H3EA 3I0VA 4UWSB 4EYBA 5ACPA 4XWWA 4LE6A 1VGNA 3VQZA 4O98A 2Y8BA 2BMIA 2FHXA 2BTNA 3R2UA 3X30A 2FK6A 2P97A 4D1VA 5ACUA 4NQ6A 2XR1A 4JO0A 2Q0IA 5LCAA 3PG4A 5HH4A 1X8IA 2WHGA 5ACQA 3T3OA 4Z6XA 5B15A 3KL7A 1WW1A 2Q9UA 3P2UA 1E5DA 5EVBA 2AIOA 3X2XA 1YCGA 2R2DA 2BG6A 5B1UA 4UA4A 2OHIA 1DXKA 4ZO2A 2BC2A 1QH5A 4TZ9A 4ZO3A 5EHTA 2ZZIA 1P9EA 3IE0A 2I7VA 4FEKA 2VW8A 2QDTA 5LLDA 2BGAA 4J5HA 2BR6A 3SRXA 2Y87A 1A8TA 5ACRA 4Z67A 1A7TA 5HH5A 5AXOA 3SPUA 3BK1A 2YCBA 5EH9A 5EV8A 3PY6A 4HL2A 3KNSA 4ZEJA 1YCFA 1YCHA 4FR7A 4WD6A 4F6HA 1KO3A 4UAMA 4GYUA 2GFKA 2ZNBA 1HLKA 5K4KA 3IE1A 4PVOA 2BIBA 5LS3A 2YZ3A 2BG8B 4FSBA 2OHHA 3DHAA 3SW3A 1XM8A 2E7YA 3IEMA 2OHJA 3SBLA 2DOOA 3SD9A 5LSCA 5HH6A 4RM5A 3I15A 4Z7RA 5KIKA 1BMCA 4NQ2A 2H6AA 5LM6A 5HIOA 3IOFA 4PVTA 3RKJA 2NXAA 4RAWA 4TZEA 5EV6A 5EVKA 4D1UA 5ACXA 3S0ZA 4AX1B 4C09A 3IEKA 1XTOA 4YSLA 2I7TA 4P62A 2QEDA 2HB9A 4U4LA 3IOGA 4TZFA 3T3NA 2WYLA 2BG8A 5K4NA 3BC2A 3T9MA 3ZR9A 5K0WA 4D1TA 4YSBA 1WRAA 3VPEA 2AZ4A 5LCFA 5FQCA 4XWTA 2WYMA 3ZNBA 1KO2A 2P1EA 4C1GA 5AHRA 2Q42A 5EW0A 2P4ZA 3ESHA 3I13A 5EWAA 4UWPB 2BFKA 4RBSA 2Y8AA 2QDSA 5EVDA 2YNVB 1KR3A 5AYAA 4C1EA 3JXPA 3IELA 5HIPA 4HKYA 1QH3A 2BG7A 2NZEA 4AX0B 4RAMA 5LE1A 2WRSA 5AHOA 4Z5ZA 4UBQA 4NQ4A 3KNRA 2FU6A 5A5ZA 4BZ3A 1WUOA 3A4YA 1WUPA 4C1FA 1JJTA 2UYXA 1ZTCA 4C1DA 4C1HA 2P18A 4XUKA 3DHBA 4AWZA 3I14A 3DH8A 2YNVA 5B3RA 4TYFA 2FM6A 2ZO4A 4TYTA 5ACTA 3PY5A 5ACWA 3QH8A 4D02A 2GFJA 3Q6VA 3MD7A 2YNWA 3BV6A 5ACSA 3LVZA 5FQBA 2GMNA 1MQOA 2QJSA 4C1CA 5AXRA 4TZBA 1X8HA 4H0DA 1BC2A 5A0VA 1JJEA 5LMCA 5KILA 5K4MA 3TP9A 1BVTA 2BFZB 4UWOB 3F9OA 4HL1A 4V0HA 4EYFA 3SFPA 4AD9A 3X2YA 3G1PA 5AEBA 4EY2A 4AWYB 4B87A 2FU7A 3FCZA 1SMLA 5A0TA 3AJ3A 4EXYA 5HIQA 4RL0A 4UWRB 3ZWFA 3BK2A 1ZKPA 5A87A 2M5DA 2BFLA 1X8GA 4CHLA 1K07A 3IE2A 5FQAA 2GCUA 4Z60A 2QINA 2YNUA 3ADRA 2YNTB
chains in the Genus database with same CATH superfamily
3FAIA 2CFUA 2FU9A 2DKFA 4F6ZA 4J5FA 2NYPA 4EFZA 1DDKA 2BFZA 3IDZA 4GCWA 4GYQA 4ZNBA 4RL2A 2Q0JA 2ZWRA 4NQ5A 4EYLA 4D1WA 4Z5YA 2FHXB 3DHCA 2WYMC 2XF4A 1VMEA 2BG2A 4KEPA 3RKKA 3X2ZA 4DIKA 2NZFA 3AF6A 2I7XA 4DILA 1JT1A 3L6NA 2FU8A 3AF5A 4EXSA 5ACVA 1L9YA 3I11A 5IQKA 1Y44A 4AV7A 2GKLA 1DD6A 4KEQA 3WXCA 3RPCA 1M2XA 2A7MA 3ZQ4A 2CBNA 1ZNBA 2M5CA 5HISA 5LCHA 4YSKA 4BP0A 1VJNA 5DPXA 2YNTA 3H3EA 3I0VA 4AXHA 4UWSB 4EYBA 5ACPA 4XWWA 4LE6A 1VGNA 3VQZA 4O98A 2Y8BA 2BMIA 2FHXA 2BTNA 3R2UA 3X30A 2FK6A 2P97A 4D1VA 5ACUA 4NQ6A 2XR1A 4JO0A 2Q0IA 5LCAA 3PG4A 5HH4A 1X8IA 2WHGA 5ACQA 3T3OA 4Z6XA 5B15A 3KL7A 1WW1A 2Q9UA 3P2UA 1E5DA 5EVBA 2AIOA 3X2XA 1YCGA 4PDXA 2R2DA 2BG6A 5B1UA 4UA4A 2OHIA 1DXKA 4ZO2A 2BC2A 1QH5A 4TZ9A 4ZO3A 5EHTA 2CFZA 2ZZIA 1P9EA 4NURA 3IE0A 2I7VA 4FEKA 2VW8A 2QDTA 5LLDA 2BGAA 4J5HA 2BR6A 3SRXA 2Y87A 1A8TA 5ACRA 4Z67A 1A7TA 5HH5A 5AXOA 3SPUA 3BK1A 2YCBA 5EH9A 5EV8A 3PY6A 4HL2A 3KNSA 4ZEJA 1YCFA 1YCHA 4FR7A 4WD6A 4F6HA 1KO3A 4UAMA 4GYUA 2GFKA 2ZNBA 1HLKA 5K4KA 3IE1A 4PVOA 2BIBA 5LS3A 2YZ3A 2BG8B 4FSBA 2OHHA 3DHAA 3SW3A 1XM8A 2E7YA 3IEMA 2OHJA 3SBLA 2DOOA 3SD9A 5LSCA 5HH6A 4RM5A 3I15A 4Z7RA 5KIKA 1BMCA 4NQ2A 2H6AA 5LM6A 5HIOA 3IOFA 4PVTA 3RKJA 2NXAA 4RAWA 4TZEA 5EV6A 5EVKA 4D1UA 5ACXA 3S0ZA 4AX1B 4C09A 3IEKA 1XTOA 4YSLA 2CG2A 2I7TA 4P62A 2QEDA 2HB9A 4U4LA 3IOGA 4TZFA 3T3NA 2WYLA 2BG8A 5K4NA 3BC2A 3T9MA 3ZR9A 5K0WA 4D1TA 4YSBA 1WRAA 3VPEA 2AZ4A 5LCFA 5FQCA 4XWTA 2WYMA 3ZNBA 1KO2A 2P1EA 4C1GA 5AHRA 2Q42A 5EW0A 2P4ZA 3ESHA 3I13A 5EWAA 4UWPB 2BFKA 4RBSA 2Y8AA 2QDSA 5EVDA 2YNVB 1KR3A 5AYAA 4C1EA 2CG3A 3JXPA 3IELA 5HIPA 4HKYA 5AJLA 1QH3A 2BG7A 2NZEA 4AX0B 4RAMA 2YHEA 5LE1A 2WRSA 5AHOA 4Z5ZA 4UBQA 4NQ4A 3KNRA 2FU6A 5A5ZA 4BZ3A 1WUOA 3A4YA 1WUPA 4C1FA 1JJTA 2UYXA 1ZTCA 4C1DA 4C1HA 2P18A 4XUKA 3DHBA 4AWZA 3I14A 3DH8A 2YNVA 5B3RA 4TYFA 5AIJA 2FM6A 2ZO4A 4TYTA 5A23A 5ACTA 3PY5A 5ACWA 3QH8A 4D02A 2GFJA 3Q6VA 3MD7A 2YNWA 3BV6A 5ACSA 3LVZA 5FQBA 2GMNA 1MQOA 2QJSA 4C1CA 5AXRA 4TZBA 1X8HA 4H0DA 1BC2A 5A0VA 1JJEA 5LMCA 5KILA 5K4MA 3TP9A 1BVTA 2BFZB 4UWOB 3F9OA 4HL1A 4V0HA 4EYFA 3SFPA 4AD9A 3X2YA 3G1PA 5AEBA 4EY2A 4AWYB 4B87A 2FU7A 3FCZA 1SMLA 5A0TA 3AJ3A 4EXYA 5HIQA 4RL0A 4UWRB 3ZWFA 3BK2A 1ZKPA 5A87A 2M5DA 2BFLA 1X8GA 4CHLA 1K07A 3IE2A 5FQAA 2GCUA 4Z60A 2QINA 2YNUA 3ADRA 2YNTB
chains in the Genus database with same CATH topology
3FAIA 2FU9A 2DKFA 4F6ZA 4J5FA 2NYPA 4EFZA 1DDKA 2BFZA 3IDZA 4GCWA 4GYQA 4ZNBA 4RL2A 2Q0JA 2ZWRA 4NQ5A 4EYLA 4D1WA 4Z5YA 2FHXB 3DHCA 2WYMC 2XF4A 1VMEA 2BG2A 4KEPA 3RKKA 3X2ZA 4DIKA 2NZFA 3AF6A 2I7XA 4DILA 1JT1A 3L6NA 2FU8A 3AF5A 4EXSA 5ACVA 1L9YA 3I11A 5IQKA 1Y44A 2GKLA 1DD6A 4KEQA 3WXCA 3RPCA 1M2XA 2A7MA 3ZQ4A 2CBNA 1ZNBA 2M5CA 5HISA 5LCHA 4YSKA 4BP0A 1VJNA 5DPXA 2YNTA 3H3EA 3I0VA 4UWSB 4EYBA 5ACPA 4XWWA 4LE6A 1VGNA 3VQZA 4O98A 2Y8BA 2BMIA 2FHXA 2BTNA 3R2UA 3X30A 2FK6A 2P97A 4D1VA 5ACUA 4NQ6A 2XR1A 4JO0A 2Q0IA 5LCAA 3PG4A 5HH4A 1X8IA 2WHGA 5ACQA 3T3OA 4Z6XA 5B15A 3KL7A 1WW1A 2Q9UA 3P2UA 1E5DA 5EVBA 2AIOA 3X2XA 1YCGA 2R2DA 2BG6A 5B1UA 4UA4A 2OHIA 1DXKA 4ZO2A 2BC2A 1QH5A 4TZ9A 4ZO3A 5EHTA 2ZZIA 1P9EA 3IE0A 2I7VA 4FEKA 2VW8A 2QDTA 5LLDA 2BGAA 4J5HA 2BR6A 3SRXA 2Y87A 1A8TA 5ACRA 4Z67A 1A7TA 5HH5A 5AXOA 3SPUA 3BK1A 2YCBA 5EH9A 5EV8A 3PY6A 4HL2A 3KNSA 4ZEJA 1YCFA 1YCHA 4FR7A 4WD6A 4F6HA 1KO3A 4UAMA 4GYUA 2GFKA 2ZNBA 1HLKA 5K4KA 3IE1A 4PVOA 2BIBA 5LS3A 2YZ3A 2BG8B 4FSBA 2OHHA 3DHAA 3SW3A 1XM8A 2E7YA 3IEMA 2OHJA 3SBLA 2DOOA 3SD9A 5LSCA 5HH6A 4RM5A 3I15A 4Z7RA 5KIKA 1BMCA 4NQ2A 2H6AA 5LM6A 5HIOA 3IOFA 4PVTA 3RKJA 2NXAA 4RAWA 4TZEA 5EV6A 5EVKA 4D1UA 5ACXA 3S0ZA 4AX1B 4C09A 3IEKA 1XTOA 4YSLA 2I7TA 4P62A 2QEDA 2HB9A 4U4LA 3IOGA 4TZFA 3T3NA 2WYLA 2BG8A 5K4NA 3BC2A 3T9MA 3ZR9A 5K0WA 4D1TA 4YSBA 1WRAA 3VPEA 2AZ4A 5LCFA 5FQCA 4XWTA 2WYMA 3ZNBA 1KO2A 2P1EA 4C1GA 5AHRA 2Q42A 5EW0A 2P4ZA 3ESHA 3I13A 5EWAA 4UWPB 2BFKA 4RBSA 2Y8AA 2QDSA 5EVDA 2YNVB 1KR3A 5AYAA 4C1EA 3JXPA 3IELA 5HIPA 4HKYA 1QH3A 2BG7A 2NZEA 4AX0B 4RAMA 5LE1A 2WRSA 5AHOA 4Z5ZA 4UBQA 4NQ4A 3KNRA 2FU6A 5A5ZA 4BZ3A 1WUOA 3A4YA 1WUPA 4C1FA 1JJTA 2UYXA 1ZTCA 4C1DA 4C1HA 2P18A 4XUKA 3DHBA 4AWZA 3I14A 3DH8A 2YNVA 5B3RA 4TYFA 2FM6A 2ZO4A 4TYTA 5ACTA 3PY5A 5ACWA 3QH8A 4D02A 2GFJA 3Q6VA 3MD7A 2YNWA 3BV6A 5ACSA 3LVZA 5FQBA 2GMNA 1MQOA 2QJSA 4C1CA 5AXRA 4TZBA 1X8HA 4H0DA 1BC2A 5A0VA 1JJEA 5LMCA 5KILA 5K4MA 3TP9A 1BVTA 2BFZB 4UWOB 3F9OA 4HL1A 4V0HA 4EYFA 3SFPA 4AD9A 3X2YA 3G1PA 5AEBA 4EY2A 4AWYB 4B87A 2FU7A 3FCZA 1SMLA 5A0TA 3AJ3A 4EXYA 5HIQA 4RL0A 4UWRB 3ZWFA 3BK2A 1ZKPA 5A87A 2M5DA 2BFLA 1X8GA 4CHLA 1K07A 3IE2A 5FQAA 2GCUA 4Z60A 2QINA 2YNUA 3ADRA 2YNTB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FAI A;  2FU9 A;  2DKF A;  4F6Z A;  4J5F A;  2NYP A;  4EFZ A;  1DDK A;  2BFZ A;  3IDZ A;  4GCW A;  4GYQ A;  4ZNB A;  4RL2 A;  2Q0J A;  2ZWR A;  4NQ5 A;  4EYL A;  4D1W A;  4Z5Y A;  2FHX B;  3DHC A;  2WYM C;  2XF4 A;  1VME A;  2BG2 A;  4KEP A;  3RKK A;  3X2Z A;  4DIK A;  2NZF A;  3AF6 A;  2I7X A;  4DIL A;  1JT1 A;  3L6N A;  2FU8 A;  3AF5 A;  4EXS A;  5ACV A;  1L9Y A;  3I11 A;  5IQK A;  1Y44 A;  2GKL A;  1DD6 A;  4KEQ A;  3WXC A;  3RPC A;  1M2X A;  2A7M A;  3ZQ4 A;  2CBN A;  1ZNB A;  2M5C A;  5HIS A;  5LCH A;  4YSK A;  4BP0 A;  1VJN A;  5DPX A;  2YNT A;  3H3E A;  3I0V A;  4UWS B;  4EYB A;  5ACP A;  4XWW A;  4LE6 A;  1VGN A;  3VQZ A;  4O98 A;  2Y8B A;  2BMI A;  2FHX A;  2BTN A;  3R2U A;  3X30 A;  2FK6 A;  2P97 A;  4D1V A;  5ACU A;  4NQ6 A;  2XR1 A;  4JO0 A;  2Q0I A;  5LCA A;  3PG4 A;  5HH4 A;  1X8I A;  2WHG A;  5ACQ A;  3T3O A;  4Z6X A;  5B15 A;  3KL7 A;  1WW1 A;  2Q9U A;  3P2U A;  1E5D A;  5EVB A;  2AIO A;  3X2X A;  1YCG A;  2R2D A;  2BG6 A;  5B1U A;  4UA4 A;  2OHI A;  1DXK A;  4ZO2 A;  2BC2 A;  1QH5 A;  4TZ9 A;  4ZO3 A;  5EHT A;  2ZZI A;  1P9E A;  3IE0 A;  2I7V A;  4FEK A;  2VW8 A;  2QDT A;  5LLD A;  2BGA A;  4J5H A;  2BR6 A;  3SRX A;  2Y87 A;  1A8T A;  5ACR A;  4Z67 A;  1A7T A;  5HH5 A;  5AXO A;  3SPU A;  3BK1 A;  2YCB A;  5EH9 A;  5EV8 A;  3PY6 A;  4HL2 A;  3KNS A;  4ZEJ A;  1YCF A;  1YCH A;  4FR7 A;  4WD6 A;  4F6H A;  1KO3 A;  4UAM A;  4GYU A;  2GFK A;  2ZNB A;  1HLK A;  5K4K A;  3IE1 A;  4PVO A;  2BIB A;  5LS3 A;  2YZ3 A;  2BG8 B;  4FSB A;  2OHH A;  3DHA A;  3SW3 A;  1XM8 A;  2E7Y A;  3IEM A;  2OHJ A;  3SBL A;  2DOO A;  3SD9 A;  5LSC A;  5HH6 A;  4RM5 A;  3I15 A;  4Z7R A;  5KIK A;  1BMC A;  4NQ2 A;  2H6A A;  5LM6 A;  5HIO A;  3IOF A;  4PVT A;  3RKJ A;  2NXA A;  4RAW A;  4TZE A;  5EV6 A;  5EVK A;  4D1U A;  5ACX A;  3S0Z A;  4AX1 B;  4C09 A;  3IEK A;  1XTO A;  4YSL A;  2I7T A;  4P62 A;  2QED A;  2HB9 A;  4U4L A;  3IOG A;  4TZF A;  3T3N A;  2WYL A;  2BG8 A;  5K4N A;  3BC2 A;  3T9M A;  3ZR9 A;  5K0W A;  4D1T A;  4YSB A;  1WRA A;  3VPE A;  2AZ4 A;  5LCF A;  5FQC A;  4XWT A;  2WYM A;  3ZNB A;  1KO2 A;  2P1E A;  4C1G A;  5AHR A;  2Q42 A;  5EW0 A;  2P4Z A;  3ESH A;  3I13 A;  5EWA A;  4UWP B;  2BFK A;  4RBS A;  2Y8A A;  2QDS A;  5EVD A;  2YNV B;  1KR3 A;  5AYA A;  4C1E A;  3JXP A;  3IEL A;  5HIP A;  4HKY A;  1QH3 A;  2BG7 A;  2NZE A;  4AX0 B;  4RAM A;  5LE1 A;  2WRS A;  5AHO A;  4Z5Z A;  4UBQ A;  4NQ4 A;  3KNR A;  2FU6 A;  5A5Z A;  4BZ3 A;  1WUO A;  3A4Y A;  1WUP A;  4C1F A;  1JJT A;  2UYX A;  1ZTC A;  4C1D A;  4C1H A;  2P18 A;  4XUK A;  3DHB A;  4AWZ A;  3I14 A;  3DH8 A;  2YNV A;  5B3R A;  4TYF A;  2FM6 A;  2ZO4 A;  4TYT A;  5ACT A;  3PY5 A;  5ACW A;  3QH8 A;  4D02 A;  2GFJ A;  3Q6V A;  3MD7 A;  2YNW A;  3BV6 A;  5ACS A;  3LVZ A;  5FQB A;  2GMN A;  1MQO A;  2QJS A;  4C1C A;  5AXR A;  4TZB A;  1X8H A;  4H0D A;  1BC2 A;  5A0V A;  1JJE A;  5LMC A;  5KIL A;  5K4M A;  3TP9 A;  1BVT A;  2BFZ B;  4UWO B;  3F9O A;  4HL1 A;  4V0H A;  4EYF A;  3SFP A;  4AD9 A;  3X2Y A;  3G1P A;  5AEB A;  4EY2 A;  4AWY B;  4B87 A;  2FU7 A;  3FCZ A;  1SML A;  5A0T A;  3AJ3 A;  4EXY A;  5HIQ A;  4RL0 A;  4UWR B;  3ZWF A;  3BK2 A;  1ZKP A;  5A87 A;  2M5D A;  2BFL A;  1X8G A;  4CHL A;  1K07 A;  3IE2 A;  5FQA A;  2GCU A;  4Z60 A;  2QIN A;  2YNU A;  3ADR A;  2YNT B; 
#chains in the Genus database with same CATH topology
 3FAI A;  2CFU A;  2FU9 A;  2DKF A;  4F6Z A;  4J5F A;  2NYP A;  4EFZ A;  1DDK A;  2BFZ A;  3IDZ A;  4GCW A;  4GYQ A;  4ZNB A;  4RL2 A;  2Q0J A;  2ZWR A;  4NQ5 A;  4EYL A;  4D1W A;  4Z5Y A;  2FHX B;  3DHC A;  2WYM C;  2XF4 A;  1VME A;  2BG2 A;  4KEP A;  3RKK A;  3X2Z A;  4DIK A;  2NZF A;  3AF6 A;  2I7X A;  4DIL A;  1JT1 A;  3L6N A;  2FU8 A;  3AF5 A;  4EXS A;  5ACV A;  1L9Y A;  3I11 A;  5IQK A;  1Y44 A;  4AV7 A;  2GKL A;  1DD6 A;  4KEQ A;  3WXC A;  3RPC A;  1M2X A;  2A7M A;  3ZQ4 A;  2CBN A;  1ZNB A;  2M5C A;  5HIS A;  5LCH A;  4YSK A;  4BP0 A;  1VJN A;  5DPX A;  2YNT A;  3H3E A;  3I0V A;  4AXH A;  4UWS B;  4EYB A;  5ACP A;  4XWW A;  4LE6 A;  1VGN A;  3VQZ A;  4O98 A;  2Y8B A;  2BMI A;  2FHX A;  2BTN A;  3R2U A;  3X30 A;  2FK6 A;  2P97 A;  4D1V A;  5ACU A;  4NQ6 A;  2XR1 A;  4JO0 A;  2Q0I A;  5LCA A;  3PG4 A;  5HH4 A;  1X8I A;  2WHG A;  5ACQ A;  3T3O A;  4Z6X A;  5B15 A;  3KL7 A;  1WW1 A;  2Q9U A;  3P2U A;  1E5D A;  5EVB A;  2AIO A;  3X2X A;  1YCG A;  4PDX A;  2R2D A;  2BG6 A;  5B1U A;  4UA4 A;  2OHI A;  1DXK A;  4ZO2 A;  2BC2 A;  1QH5 A;  4TZ9 A;  4ZO3 A;  5EHT A;  2CFZ A;  2ZZI A;  1P9E A;  4NUR A;  3IE0 A;  2I7V A;  4FEK A;  2VW8 A;  2QDT A;  5LLD A;  2BGA A;  4J5H A;  2BR6 A;  3SRX A;  2Y87 A;  1A8T A;  5ACR A;  4Z67 A;  1A7T A;  5HH5 A;  5AXO A;  3SPU A;  3BK1 A;  2YCB A;  5EH9 A;  5EV8 A;  3PY6 A;  4HL2 A;  3KNS A;  4ZEJ A;  1YCF A;  1YCH A;  4FR7 A;  4WD6 A;  4F6H A;  1KO3 A;  4UAM A;  4GYU A;  2GFK A;  2ZNB A;  1HLK A;  5K4K A;  3IE1 A;  4PVO A;  2BIB A;  5LS3 A;  2YZ3 A;  2BG8 B;  4FSB A;  2OHH A;  3DHA A;  3SW3 A;  1XM8 A;  2E7Y A;  3IEM A;  2OHJ A;  3SBL A;  2DOO A;  3SD9 A;  5LSC A;  5HH6 A;  4RM5 A;  3I15 A;  4Z7R A;  5KIK A;  1BMC A;  4NQ2 A;  2H6A A;  5LM6 A;  5HIO A;  3IOF A;  4PVT A;  3RKJ A;  2NXA A;  4RAW A;  4TZE A;  5EV6 A;  5EVK A;  4D1U A;  5ACX A;  3S0Z A;  4AX1 B;  4C09 A;  3IEK A;  1XTO A;  4YSL A;  2CG2 A;  2I7T A;  4P62 A;  2QED A;  2HB9 A;  4U4L A;  3IOG A;  4TZF A;  3T3N A;  2WYL A;  2BG8 A;  5K4N A;  3BC2 A;  3T9M A;  3ZR9 A;  5K0W A;  4D1T A;  4YSB A;  1WRA A;  3VPE A;  2AZ4 A;  5LCF A;  5FQC A;  4XWT A;  2WYM A;  3ZNB A;  1KO2 A;  2P1E A;  4C1G A;  5AHR A;  2Q42 A;  5EW0 A;  2P4Z A;  3ESH A;  3I13 A;  5EWA A;  4UWP B;  2BFK A;  4RBS A;  2Y8A A;  2QDS A;  5EVD A;  2YNV B;  1KR3 A;  5AYA A;  4C1E A;  2CG3 A;  3JXP A;  3IEL A;  5HIP A;  4HKY A;  5AJL A;  1QH3 A;  2BG7 A;  2NZE A;  4AX0 B;  4RAM A;  2YHE A;  5LE1 A;  2WRS A;  5AHO A;  4Z5Z A;  4UBQ A;  4NQ4 A;  3KNR A;  2FU6 A;  5A5Z A;  4BZ3 A;  1WUO A;  3A4Y A;  1WUP A;  4C1F A;  1JJT A;  2UYX A;  1ZTC A;  4C1D A;  4C1H A;  2P18 A;  4XUK A;  3DHB A;  4AWZ A;  3I14 A;  3DH8 A;  2YNV A;  5B3R A;  4TYF A;  5AIJ A;  2FM6 A;  2ZO4 A;  4TYT A;  5A23 A;  5ACT A;  3PY5 A;  5ACW A;  3QH8 A;  4D02 A;  2GFJ A;  3Q6V A;  3MD7 A;  2YNW A;  3BV6 A;  5ACS A;  3LVZ A;  5FQB A;  2GMN A;  1MQO A;  2QJS A;  4C1C A;  5AXR A;  4TZB A;  1X8H A;  4H0D A;  1BC2 A;  5A0V A;  1JJE A;  5LMC A;  5KIL A;  5K4M A;  3TP9 A;  1BVT A;  2BFZ B;  4UWO B;  3F9O A;  4HL1 A;  4V0H A;  4EYF A;  3SFP A;  4AD9 A;  3X2Y A;  3G1P A;  5AEB A;  4EY2 A;  4AWY B;  4B87 A;  2FU7 A;  3FCZ A;  1SML A;  5A0T A;  3AJ3 A;  4EXY A;  5HIQ A;  4RL0 A;  4UWR B;  3ZWF A;  3BK2 A;  1ZKP A;  5A87 A;  2M5D A;  2BFL A;  1X8G A;  4CHL A;  1K07 A;  3IE2 A;  5FQA A;  2GCU A;  4Z60 A;  2QIN A;  2YNU A;  3ADR A;  2YNT B; 
#chains in the Genus database with same CATH homology
 3FAI A;  2FU9 A;  2DKF A;  4F6Z A;  4J5F A;  2NYP A;  4EFZ A;  1DDK A;  2BFZ A;  3IDZ A;  4GCW A;  4GYQ A;  4ZNB A;  4RL2 A;  2Q0J A;  2ZWR A;  4NQ5 A;  4EYL A;  4D1W A;  4Z5Y A;  2FHX B;  3DHC A;  2WYM C;  2XF4 A;  1VME A;  2BG2 A;  4KEP A;  3RKK A;  3X2Z A;  4DIK A;  2NZF A;  3AF6 A;  2I7X A;  4DIL A;  1JT1 A;  3L6N A;  2FU8 A;  3AF5 A;  4EXS A;  5ACV A;  1L9Y A;  3I11 A;  5IQK A;  1Y44 A;  2GKL A;  1DD6 A;  4KEQ A;  3WXC A;  3RPC A;  1M2X A;  2A7M A;  3ZQ4 A;  2CBN A;  1ZNB A;  2M5C A;  5HIS A;  5LCH A;  4YSK A;  4BP0 A;  1VJN A;  5DPX A;  2YNT A;  3H3E A;  3I0V A;  4UWS B;  4EYB A;  5ACP A;  4XWW A;  4LE6 A;  1VGN A;  3VQZ A;  4O98 A;  2Y8B A;  2BMI A;  2FHX A;  2BTN A;  3R2U A;  3X30 A;  2FK6 A;  2P97 A;  4D1V A;  5ACU A;  4NQ6 A;  2XR1 A;  4JO0 A;  2Q0I A;  5LCA A;  3PG4 A;  5HH4 A;  1X8I A;  2WHG A;  5ACQ A;  3T3O A;  4Z6X A;  5B15 A;  3KL7 A;  1WW1 A;  2Q9U A;  3P2U A;  1E5D A;  5EVB A;  2AIO A;  3X2X A;  1YCG A;  2R2D A;  2BG6 A;  5B1U A;  4UA4 A;  2OHI A;  1DXK A;  4ZO2 A;  2BC2 A;  1QH5 A;  4TZ9 A;  4ZO3 A;  5EHT A;  2ZZI A;  1P9E A;  3IE0 A;  2I7V A;  4FEK A;  2VW8 A;  2QDT A;  5LLD A;  2BGA A;  4J5H A;  2BR6 A;  3SRX A;  2Y87 A;  1A8T A;  5ACR A;  4Z67 A;  1A7T A;  5HH5 A;  5AXO A;  3SPU A;  3BK1 A;  2YCB A;  5EH9 A;  5EV8 A;  3PY6 A;  4HL2 A;  3KNS A;  4ZEJ A;  1YCF A;  1YCH A;  4FR7 A;  4WD6 A;  4F6H A;  1KO3 A;  4UAM A;  4GYU A;  2GFK A;  2ZNB A;  1HLK A;  5K4K A;  3IE1 A;  4PVO A;  2BIB A;  5LS3 A;  2YZ3 A;  2BG8 B;  4FSB A;  2OHH A;  3DHA A;  3SW3 A;  1XM8 A;  2E7Y A;  3IEM A;  2OHJ A;  3SBL A;  2DOO A;  3SD9 A;  5LSC A;  5HH6 A;  4RM5 A;  3I15 A;  4Z7R A;  5KIK A;  1BMC A;  4NQ2 A;  2H6A A;  5LM6 A;  5HIO A;  3IOF A;  4PVT A;  3RKJ A;  2NXA A;  4RAW A;  4TZE A;  5EV6 A;  5EVK A;  4D1U A;  5ACX A;  3S0Z A;  4AX1 B;  4C09 A;  3IEK A;  1XTO A;  4YSL A;  2I7T A;  4P62 A;  2QED A;  2HB9 A;  4U4L A;  3IOG A;  4TZF A;  3T3N A;  2WYL A;  2BG8 A;  5K4N A;  3BC2 A;  3T9M A;  3ZR9 A;  5K0W A;  4D1T A;  4YSB A;  1WRA A;  3VPE A;  2AZ4 A;  5LCF A;  5FQC A;  4XWT A;  2WYM A;  3ZNB A;  1KO2 A;  2P1E A;  4C1G A;  5AHR A;  2Q42 A;  5EW0 A;  2P4Z A;  3ESH A;  3I13 A;  5EWA A;  4UWP B;  2BFK A;  4RBS A;  2Y8A A;  2QDS A;  5EVD A;  2YNV B;  1KR3 A;  5AYA A;  4C1E A;  3JXP A;  3IEL A;  5HIP A;  4HKY A;  1QH3 A;  2BG7 A;  2NZE A;  4AX0 B;  4RAM A;  5LE1 A;  2WRS A;  5AHO A;  4Z5Z A;  4UBQ A;  4NQ4 A;  3KNR A;  2FU6 A;  5A5Z A;  4BZ3 A;  1WUO A;  3A4Y A;  1WUP A;  4C1F A;  1JJT A;  2UYX A;  1ZTC A;  4C1D A;  4C1H A;  2P18 A;  4XUK A;  3DHB A;  4AWZ A;  3I14 A;  3DH8 A;  2YNV A;  5B3R A;  4TYF A;  2FM6 A;  2ZO4 A;  4TYT A;  5ACT A;  3PY5 A;  5ACW A;  3QH8 A;  4D02 A;  2GFJ A;  3Q6V A;  3MD7 A;  2YNW A;  3BV6 A;  5ACS A;  3LVZ A;  5FQB A;  2GMN A;  1MQO A;  2QJS A;  4C1C A;  5AXR A;  4TZB A;  1X8H A;  4H0D A;  1BC2 A;  5A0V A;  1JJE A;  5LMC A;  5KIL A;  5K4M A;  3TP9 A;  1BVT A;  2BFZ B;  4UWO B;  3F9O A;  4HL1 A;  4V0H A;  4EYF A;  3SFP A;  4AD9 A;  3X2Y A;  3G1P A;  5AEB A;  4EY2 A;  4AWY B;  4B87 A;  2FU7 A;  3FCZ A;  1SML A;  5A0T A;  3AJ3 A;  4EXY A;  5HIQ A;  4RL0 A;  4UWR B;  3ZWF A;  3BK2 A;  1ZKP A;  5A87 A;  2M5D A;  2BFL A;  1X8G A;  4CHL A;  1K07 A;  3IE2 A;  5FQA A;  2GCU A;  4Z60 A;  2QIN A;  2YNU A;  3ADR A;  2YNT B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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