5K4NA

Directed evolutionary changes in mbl super family - ndm-1 round 10 crystal-2
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
228
structure length
228
Chain Sequence
DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Enzyme evolvability is contingent on the initial sequence background
rcsb
molecule tags Hydrolase
source organism Klebsiella pneumoniae
molecule keywords Metallo-beta-lactamase type 2
total genus 75
structure length 228
sequence length 228
ec nomenclature
pdb deposition date 2016-05-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5k4nA00
5AXRA 2BTNA 3PG4A 1HLKA 1WRAA 1X8GA 4RL2A 4ZO3A 1QH5A 5AXOA 4J5FA 4C09A 2YNVB 4H0DA 4RL0A 1YCFA 4EYBA 3SFPA 4XUKA 2WHGA 1XTOA 4DILA 2P18A 4KEPA 2FHXA 5B15A 3F9OA 1M2XA 4F6HA 4RAWA 2YNTA 3IOGA 2FM6A 3G1PA 2BGAA 3DHCA 3IOFA 4YSKA 1ZTCA 2DKFA 2FU6A 2OHIA 5HH4A 2GMNA 1YCHA 2OHJA 1L9YA 5FQAA 4EXSA 3KL7A 4BP0A 5ACQA 2NZEA 1JJTA 1VMEA 4KEQA 2CBNA 1DDKA 4C1EA 3VPEA 1BC2A 5EVKA 4UA4A 3ZR9A 5A87A 2NXAA 1BVTA 3IE2A 3I11A 2QDSA 3VQZA 5AHOA 1JT1A 3DHBA 4D1UA 3IEMA 5K4MA 4Z7RA 4AWYB 4LE6A 5HIQA 3P2UA 4UBQA 2ZWRA 4YSBA 2BG7A 5B1UA 2BFKA 4GYUA 2BFLA 2OHHA 4CHLA 2M5DA 2Q9UA 4ZNBA 3PY6A 4Z6XA 4ZEJA 2E7YA 1P9EA 4D1VA 1KR3A 2ZNBA 5FQCA 4NQ2A 4PVOA 3ESHA 5HH5A 5ACRA 5LSCA 5EW0A 4JO0A 4O98A 2Y87A 5EVDA 1X8HA 2BG8B 2Q0JA 2Y8BA 5EWAA 4UWRB 4RBSA 3PY5A 2P4ZA 3X2XA 1DXKA 5HIOA 3BC2A 2FU9A 1BMCA 2BR6A 4EY2A 5EV8A 3BK1A 3KNRA 5AEBA 2AZ4A 2NZFA 3T3OA 2BFZA 4EYFA 2BC2A 2P1EA 3H3EA 1KO3A 4F6ZA 1A7TA 3MD7A 4UWPB 4AX0B 4UAMA 5LE1A 2YCBA 2GFKA 1A8TA 1YCGA 1XM8A 3ZNBA 4PVTA 1Y44A 1QH3A 3T9MA 4J5HA 4TZ9A 4FSBA 2QJSA 3RPCA 2H6AA 3ZQ4A 4TZFA 3I14A 5AHRA 5AYAA 4Z5YA 3LVZA 2FHXB 4FEKA 4C1DA 5ACSA 3ADRA 2YNTB 4TZEA 3SBLA 5EHTA 3FAIA 5KIKA 2QINA 3X2ZA 4BZ3A 2QEDA 5ACXA 1X8IA 2FK6A 3IDZA 2I7XA 2GKLA 1KO2A 1DD6A 1WW1A 4V0HA 2FU7A 2WYLA 3Q6VA 4Z60A 3I15A 3IEKA 2I7TA 1K07A 2Q42A 4C1HA 3AJ3A 5LCFA 2ZZIA 2GFJA 3BK2A 5ACUA 3FCZA 4RM5A 1MQOA 4C1CA 5K0WA 4Z67A 4AWZA 2XR1A 4UWSB 1VJNA 2WRSA 2VW8A 5A0VA 3AF5A 4NQ4A 3TP9A 5LMCA 3RKJA 4FR7A 2BG6A 2ZO4A 4TZBA 4HKYA 4D02A 2Q0IA 2P97A 3S0ZA 5FQBA 2YNVA 1WUPA 5ACTA 5LLDA 3JXPA 4DIKA 1VGNA 4TYFA 5HH6A 2YNUA 3X2YA 2I7VA 3R2UA 5LS3A 3DH8A 2UYXA 1ZNBA 2M5CA 3IE0A 4HL2A 4Z5ZA 1JJEA 5LM6A 4UWOB 5LCHA 5K4KA 3DHAA 2QDTA 5KILA 5A0TA 3QH8A 4AD9A 4GCWA 3SRXA 3X30A 2YZ3A 2BG2A 2A7MA 5DPXA 5ACWA 4EXYA 3I0VA 5A5ZA 5IQKA 1SMLA 2BFZB 5EV6A 4NQ5A 2HB9A 4U4LA 4EFZA 2BIBA 1ZKPA 4P62A 4HL1A 5B3RA 4TYTA 3IE1A 2WYMA 2Y8AA 2DOOA 3IELA 5K4NA 2WYMC 4C1FA 3SPUA 5EVBA 3T3NA 5LCAA 1E5DA 3KNSA 2XF4A 3BV6A 4XWTA 4WD6A 4ZO2A 3L6NA 2GCUA 4NQ6A 2R2DA 1WUOA 4D1WA 3WXCA 4B87A 4D1TA 3RKKA 2AIOA 2NYPA 3A4YA 4EYLA 4YSLA 3ZWFA 5EH9A 5HISA 3I13A 3SD9A 3SW3A 5ACVA 4RAMA 4C1GA 2BG8A 4AX1B 3AF6A 4XWWA 5ACPA 2FU8A 2BMIA 2YNWA 4GYQA 5HIPA
chains in the Genus database with same CATH superfamily
5AXRA 2BTNA 3PG4A 1HLKA 1WRAA 1X8GA 4RL2A 4ZO3A 1QH5A 2CG3A 5AXOA 4J5FA 5A23A 4C09A 2YNVB 4H0DA 4RL0A 1YCFA 4EYBA 3SFPA 4XUKA 2WHGA 1XTOA 4DILA 2P18A 4KEPA 2FHXA 5B15A 3F9OA 1M2XA 4F6HA 4RAWA 2YNTA 3IOGA 2FM6A 3G1PA 2BGAA 3DHCA 3IOFA 4YSKA 1ZTCA 2DKFA 2FU6A 2OHIA 5HH4A 2GMNA 1YCHA 2OHJA 1L9YA 5FQAA 4EXSA 3KL7A 4BP0A 5ACQA 2NZEA 2CG2A 1JJTA 1VMEA 4KEQA 2CBNA 1DDKA 4C1EA 3VPEA 1BC2A 5EVKA 4UA4A 3ZR9A 5A87A 2NXAA 1BVTA 3IE2A 3I11A 2QDSA 3VQZA 5AHOA 1JT1A 3DHBA 4D1UA 3IEMA 5K4MA 4Z7RA 4AWYB 4LE6A 5HIQA 3P2UA 4UBQA 2ZWRA 4YSBA 2BG7A 5B1UA 2BFKA 4GYUA 2BFLA 2OHHA 4CHLA 2M5DA 2Q9UA 4ZNBA 3PY6A 4Z6XA 4ZEJA 2E7YA 1P9EA 4D1VA 1KR3A 2ZNBA 5FQCA 4NQ2A 4PVOA 3ESHA 5HH5A 5ACRA 5LSCA 5EW0A 4JO0A 4O98A 2Y87A 5EVDA 1X8HA 2BG8B 2Q0JA 2Y8BA 5EWAA 4UWRB 4RBSA 3PY5A 2P4ZA 3X2XA 1DXKA 5HIOA 3BC2A 2FU9A 5AJLA 1BMCA 2BR6A 4EY2A 5EV8A 3BK1A 3KNRA 5AEBA 2AZ4A 2NZFA 3T3OA 2BFZA 4EYFA 2BC2A 2P1EA 3H3EA 1KO3A 4F6ZA 1A7TA 3MD7A 4UWPB 4AX0B 4UAMA 5LE1A 2YCBA 2GFKA 1A8TA 1YCGA 1XM8A 3ZNBA 4PVTA 1Y44A 1QH3A 3T9MA 4J5HA 4TZ9A 4FSBA 2QJSA 3RPCA 2H6AA 3ZQ4A 4TZFA 3I14A 5AHRA 5AYAA 4Z5YA 3LVZA 2FHXB 4FEKA 4C1DA 5ACSA 3ADRA 2YNTB 4TZEA 3SBLA 5EHTA 3FAIA 5KIKA 2QINA 3X2ZA 4BZ3A 4PDXA 2QEDA 5ACXA 1X8IA 2FK6A 3IDZA 2YHEA 2I7XA 2GKLA 1KO2A 1DD6A 1WW1A 4V0HA 2FU7A 2WYLA 3Q6VA 4Z60A 3I15A 4AXHA 3IEKA 2I7TA 1K07A 2Q42A 4C1HA 3AJ3A 5LCFA 2ZZIA 2GFJA 3BK2A 5ACUA 3FCZA 4RM5A 5AIJA 1MQOA 4C1CA 5K0WA 4Z67A 4AWZA 2XR1A 4UWSB 1VJNA 2WRSA 2VW8A 5A0VA 3AF5A 4NQ4A 3TP9A 5LMCA 3RKJA 4FR7A 2BG6A 2ZO4A 4TZBA 4HKYA 4D02A 2Q0IA 2P97A 3S0ZA 5FQBA 2YNVA 1WUPA 5ACTA 5LLDA 4NURA 3JXPA 4DIKA 1VGNA 4TYFA 5HH6A 2YNUA 3X2YA 2I7VA 3R2UA 5LS3A 3DH8A 2UYXA 1ZNBA 2M5CA 3IE0A 4HL2A 4Z5ZA 1JJEA 5LM6A 4UWOB 5LCHA 5K4KA 3DHAA 2CFUA 2QDTA 5KILA 5A0TA 3QH8A 4AD9A 4AV7A 4GCWA 3SRXA 3X30A 2CFZA 2YZ3A 2BG2A 2A7MA 5DPXA 5ACWA 4EXYA 3I0VA 5A5ZA 5IQKA 1SMLA 2BFZB 5EV6A 4NQ5A 2HB9A 4U4LA 4EFZA 2BIBA 1ZKPA 4P62A 4HL1A 5B3RA 4TYTA 3IE1A 2WYMA 2Y8AA 2DOOA 3IELA 5K4NA 2WYMC 4C1FA 3SPUA 5EVBA 3T3NA 5LCAA 1E5DA 3KNSA 2XF4A 3BV6A 4XWTA 4WD6A 4ZO2A 3L6NA 2GCUA 4NQ6A 2R2DA 1WUOA 4D1WA 3WXCA 4B87A 4D1TA 3RKKA 2AIOA 2NYPA 3A4YA 4EYLA 4YSLA 3ZWFA 5EH9A 5HISA 3I13A 3SD9A 3SW3A 5ACVA 4RAMA 4C1GA 2BG8A 4AX1B 3AF6A 4XWWA 5ACPA 2FU8A 2BMIA 2YNWA 4GYQA 5HIPA
chains in the Genus database with same CATH topology
5AXRA 2BTNA 3PG4A 1HLKA 1WRAA 1X8GA 4RL2A 4ZO3A 1QH5A 5AXOA 4J5FA 4C09A 2YNVB 4H0DA 4RL0A 1YCFA 4EYBA 3SFPA 4XUKA 2WHGA 1XTOA 4DILA 2P18A 4KEPA 2FHXA 5B15A 3F9OA 1M2XA 4F6HA 4RAWA 2YNTA 3IOGA 2FM6A 3G1PA 2BGAA 3DHCA 3IOFA 4YSKA 1ZTCA 2DKFA 2FU6A 2OHIA 5HH4A 2GMNA 1YCHA 2OHJA 1L9YA 5FQAA 4EXSA 3KL7A 4BP0A 5ACQA 2NZEA 1JJTA 1VMEA 4KEQA 2CBNA 1DDKA 4C1EA 3VPEA 1BC2A 5EVKA 4UA4A 3ZR9A 5A87A 2NXAA 1BVTA 3IE2A 3I11A 2QDSA 3VQZA 5AHOA 1JT1A 3DHBA 4D1UA 3IEMA 5K4MA 4Z7RA 4AWYB 4LE6A 5HIQA 3P2UA 4UBQA 2ZWRA 4YSBA 2BG7A 5B1UA 2BFKA 4GYUA 2BFLA 2OHHA 4CHLA 2M5DA 2Q9UA 4ZNBA 3PY6A 4Z6XA 4ZEJA 2E7YA 1P9EA 4D1VA 1KR3A 2ZNBA 5FQCA 4NQ2A 4PVOA 3ESHA 5HH5A 5ACRA 5LSCA 5EW0A 4JO0A 4O98A 2Y87A 5EVDA 1X8HA 2BG8B 2Q0JA 2Y8BA 5EWAA 4UWRB 4RBSA 3PY5A 2P4ZA 3X2XA 1DXKA 5HIOA 3BC2A 2FU9A 1BMCA 2BR6A 4EY2A 5EV8A 3BK1A 3KNRA 5AEBA 2AZ4A 2NZFA 3T3OA 2BFZA 4EYFA 2BC2A 2P1EA 3H3EA 1KO3A 4F6ZA 1A7TA 3MD7A 4UWPB 4AX0B 4UAMA 5LE1A 2YCBA 2GFKA 1A8TA 1YCGA 1XM8A 3ZNBA 4PVTA 1Y44A 1QH3A 3T9MA 4J5HA 4TZ9A 4FSBA 2QJSA 3RPCA 2H6AA 3ZQ4A 4TZFA 3I14A 5AHRA 5AYAA 4Z5YA 3LVZA 2FHXB 4FEKA 4C1DA 5ACSA 3ADRA 2YNTB 4TZEA 3SBLA 5EHTA 3FAIA 5KIKA 2QINA 3X2ZA 4BZ3A 2QEDA 5ACXA 1X8IA 2FK6A 3IDZA 2I7XA 2GKLA 1KO2A 1DD6A 1WW1A 4V0HA 2FU7A 2WYLA 3Q6VA 4Z60A 3I15A 3IEKA 2I7TA 1K07A 2Q42A 4C1HA 3AJ3A 5LCFA 2ZZIA 2GFJA 3BK2A 5ACUA 3FCZA 4RM5A 1MQOA 4C1CA 5K0WA 4Z67A 4AWZA 2XR1A 4UWSB 1VJNA 2WRSA 2VW8A 5A0VA 3AF5A 4NQ4A 3TP9A 5LMCA 3RKJA 4FR7A 2BG6A 2ZO4A 4TZBA 4HKYA 4D02A 2Q0IA 2P97A 3S0ZA 5FQBA 2YNVA 1WUPA 5ACTA 5LLDA 3JXPA 4DIKA 1VGNA 4TYFA 5HH6A 2YNUA 3X2YA 2I7VA 3R2UA 5LS3A 3DH8A 2UYXA 1ZNBA 2M5CA 3IE0A 4HL2A 4Z5ZA 1JJEA 5LM6A 4UWOB 5LCHA 5K4KA 3DHAA 2QDTA 5KILA 5A0TA 3QH8A 4AD9A 4GCWA 3SRXA 3X30A 2YZ3A 2BG2A 2A7MA 5DPXA 5ACWA 4EXYA 3I0VA 5A5ZA 5IQKA 1SMLA 2BFZB 5EV6A 4NQ5A 2HB9A 4U4LA 4EFZA 2BIBA 1ZKPA 4P62A 4HL1A 5B3RA 4TYTA 3IE1A 2WYMA 2Y8AA 2DOOA 3IELA 5K4NA 2WYMC 4C1FA 3SPUA 5EVBA 3T3NA 5LCAA 1E5DA 3KNSA 2XF4A 3BV6A 4XWTA 4WD6A 4ZO2A 3L6NA 2GCUA 4NQ6A 2R2DA 1WUOA 4D1WA 3WXCA 4B87A 4D1TA 3RKKA 2AIOA 2NYPA 3A4YA 4EYLA 4YSLA 3ZWFA 5EH9A 5HISA 3I13A 3SD9A 3SW3A 5ACVA 4RAMA 4C1GA 2BG8A 4AX1B 3AF6A 4XWWA 5ACPA 2FU8A 2BMIA 2YNWA 4GYQA 5HIPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5AXR A;  2BTN A;  3PG4 A;  1HLK A;  1WRA A;  1X8G A;  4RL2 A;  4ZO3 A;  1QH5 A;  5AXO A;  4J5F A;  4C09 A;  2YNV B;  4H0D A;  4RL0 A;  1YCF A;  4EYB A;  3SFP A;  4XUK A;  2WHG A;  1XTO A;  4DIL A;  2P18 A;  4KEP A;  2FHX A;  5B15 A;  3F9O A;  1M2X A;  4F6H A;  4RAW A;  2YNT A;  3IOG A;  2FM6 A;  3G1P A;  2BGA A;  3DHC A;  3IOF A;  4YSK A;  1ZTC A;  2DKF A;  2FU6 A;  2OHI A;  5HH4 A;  2GMN A;  1YCH A;  2OHJ A;  1L9Y A;  5FQA A;  4EXS A;  3KL7 A;  4BP0 A;  5ACQ A;  2NZE A;  1JJT A;  1VME A;  4KEQ A;  2CBN A;  1DDK A;  4C1E A;  3VPE A;  1BC2 A;  5EVK A;  4UA4 A;  3ZR9 A;  5A87 A;  2NXA A;  1BVT A;  3IE2 A;  3I11 A;  2QDS A;  3VQZ A;  5AHO A;  1JT1 A;  3DHB A;  4D1U A;  3IEM A;  5K4M A;  4Z7R A;  4AWY B;  4LE6 A;  5HIQ A;  3P2U A;  4UBQ A;  2ZWR A;  4YSB A;  2BG7 A;  5B1U A;  2BFK A;  4GYU A;  2BFL A;  2OHH A;  4CHL A;  2M5D A;  2Q9U A;  4ZNB A;  3PY6 A;  4Z6X A;  4ZEJ A;  2E7Y A;  1P9E A;  4D1V A;  1KR3 A;  2ZNB A;  5FQC A;  4NQ2 A;  4PVO A;  3ESH A;  5HH5 A;  5ACR A;  5LSC A;  5EW0 A;  4JO0 A;  4O98 A;  2Y87 A;  5EVD A;  1X8H A;  2BG8 B;  2Q0J A;  2Y8B A;  5EWA A;  4UWR B;  4RBS A;  3PY5 A;  2P4Z A;  3X2X A;  1DXK A;  5HIO A;  3BC2 A;  2FU9 A;  1BMC A;  2BR6 A;  4EY2 A;  5EV8 A;  3BK1 A;  3KNR A;  5AEB A;  2AZ4 A;  2NZF A;  3T3O A;  2BFZ A;  4EYF A;  2BC2 A;  2P1E A;  3H3E A;  1KO3 A;  4F6Z A;  1A7T A;  3MD7 A;  4UWP B;  4AX0 B;  4UAM A;  5LE1 A;  2YCB A;  2GFK A;  1A8T A;  1YCG A;  1XM8 A;  3ZNB A;  4PVT A;  1Y44 A;  1QH3 A;  3T9M A;  4J5H A;  4TZ9 A;  4FSB A;  2QJS A;  3RPC A;  2H6A A;  3ZQ4 A;  4TZF A;  3I14 A;  5AHR A;  5AYA A;  4Z5Y A;  3LVZ A;  2FHX B;  4FEK A;  4C1D A;  5ACS A;  3ADR A;  2YNT B;  4TZE A;  3SBL A;  5EHT A;  3FAI A;  5KIK A;  2QIN A;  3X2Z A;  4BZ3 A;  2QED A;  5ACX A;  1X8I A;  2FK6 A;  3IDZ A;  2I7X A;  2GKL A;  1KO2 A;  1DD6 A;  1WW1 A;  4V0H A;  2FU7 A;  2WYL A;  3Q6V A;  4Z60 A;  3I15 A;  3IEK A;  2I7T A;  1K07 A;  2Q42 A;  4C1H A;  3AJ3 A;  5LCF A;  2ZZI A;  2GFJ A;  3BK2 A;  5ACU A;  3FCZ A;  4RM5 A;  1MQO A;  4C1C A;  5K0W A;  4Z67 A;  4AWZ A;  2XR1 A;  4UWS B;  1VJN A;  2WRS A;  2VW8 A;  5A0V A;  3AF5 A;  4NQ4 A;  3TP9 A;  5LMC A;  3RKJ A;  4FR7 A;  2BG6 A;  2ZO4 A;  4TZB A;  4HKY A;  4D02 A;  2Q0I A;  2P97 A;  3S0Z A;  5FQB A;  2YNV A;  1WUP A;  5ACT A;  5LLD A;  3JXP A;  4DIK A;  1VGN A;  4TYF A;  5HH6 A;  2YNU A;  3X2Y A;  2I7V A;  3R2U A;  5LS3 A;  3DH8 A;  2UYX A;  1ZNB A;  2M5C A;  3IE0 A;  4HL2 A;  4Z5Z A;  1JJE A;  5LM6 A;  4UWO B;  5LCH A;  5K4K A;  3DHA A;  2QDT A;  5KIL A;  5A0T A;  3QH8 A;  4AD9 A;  4GCW A;  3SRX A;  3X30 A;  2YZ3 A;  2BG2 A;  2A7M A;  5DPX A;  5ACW A;  4EXY A;  3I0V A;  5A5Z A;  5IQK A;  1SML A;  2BFZ B;  5EV6 A;  4NQ5 A;  2HB9 A;  4U4L A;  4EFZ A;  2BIB A;  1ZKP A;  4P62 A;  4HL1 A;  5B3R A;  4TYT A;  3IE1 A;  2WYM A;  2Y8A A;  2DOO A;  3IEL A;  5K4N A;  2WYM C;  4C1F A;  3SPU A;  5EVB A;  3T3N A;  5LCA A;  1E5D A;  3KNS A;  2XF4 A;  3BV6 A;  4XWT A;  4WD6 A;  4ZO2 A;  3L6N A;  2GCU A;  4NQ6 A;  2R2D A;  1WUO A;  4D1W A;  3WXC A;  4B87 A;  4D1T A;  3RKK A;  2AIO A;  2NYP A;  3A4Y A;  4EYL A;  4YSL A;  3ZWF A;  5EH9 A;  5HIS A;  3I13 A;  3SD9 A;  3SW3 A;  5ACV A;  4RAM A;  4C1G A;  2BG8 A;  4AX1 B;  3AF6 A;  4XWW A;  5ACP A;  2FU8 A;  2BMI A;  2YNW A;  4GYQ A;  5HIP A; 
#chains in the Genus database with same CATH topology
 5AXR A;  2BTN A;  3PG4 A;  1HLK A;  1WRA A;  1X8G A;  4RL2 A;  4ZO3 A;  1QH5 A;  2CG3 A;  5AXO A;  4J5F A;  5A23 A;  4C09 A;  2YNV B;  4H0D A;  4RL0 A;  1YCF A;  4EYB A;  3SFP A;  4XUK A;  2WHG A;  1XTO A;  4DIL A;  2P18 A;  4KEP A;  2FHX A;  5B15 A;  3F9O A;  1M2X A;  4F6H A;  4RAW A;  2YNT A;  3IOG A;  2FM6 A;  3G1P A;  2BGA A;  3DHC A;  3IOF A;  4YSK A;  1ZTC A;  2DKF A;  2FU6 A;  2OHI A;  5HH4 A;  2GMN A;  1YCH A;  2OHJ A;  1L9Y A;  5FQA A;  4EXS A;  3KL7 A;  4BP0 A;  5ACQ A;  2NZE A;  2CG2 A;  1JJT A;  1VME A;  4KEQ A;  2CBN A;  1DDK A;  4C1E A;  3VPE A;  1BC2 A;  5EVK A;  4UA4 A;  3ZR9 A;  5A87 A;  2NXA A;  1BVT A;  3IE2 A;  3I11 A;  2QDS A;  3VQZ A;  5AHO A;  1JT1 A;  3DHB A;  4D1U A;  3IEM A;  5K4M A;  4Z7R A;  4AWY B;  4LE6 A;  5HIQ A;  3P2U A;  4UBQ A;  2ZWR A;  4YSB A;  2BG7 A;  5B1U A;  2BFK A;  4GYU A;  2BFL A;  2OHH A;  4CHL A;  2M5D A;  2Q9U A;  4ZNB A;  3PY6 A;  4Z6X A;  4ZEJ A;  2E7Y A;  1P9E A;  4D1V A;  1KR3 A;  2ZNB A;  5FQC A;  4NQ2 A;  4PVO A;  3ESH A;  5HH5 A;  5ACR A;  5LSC A;  5EW0 A;  4JO0 A;  4O98 A;  2Y87 A;  5EVD A;  1X8H A;  2BG8 B;  2Q0J A;  2Y8B A;  5EWA A;  4UWR B;  4RBS A;  3PY5 A;  2P4Z A;  3X2X A;  1DXK A;  5HIO A;  3BC2 A;  2FU9 A;  5AJL A;  1BMC A;  2BR6 A;  4EY2 A;  5EV8 A;  3BK1 A;  3KNR A;  5AEB A;  2AZ4 A;  2NZF A;  3T3O A;  2BFZ A;  4EYF A;  2BC2 A;  2P1E A;  3H3E A;  1KO3 A;  4F6Z A;  1A7T A;  3MD7 A;  4UWP B;  4AX0 B;  4UAM A;  5LE1 A;  2YCB A;  2GFK A;  1A8T A;  1YCG A;  1XM8 A;  3ZNB A;  4PVT A;  1Y44 A;  1QH3 A;  3T9M A;  4J5H A;  4TZ9 A;  4FSB A;  2QJS A;  3RPC A;  2H6A A;  3ZQ4 A;  4TZF A;  3I14 A;  5AHR A;  5AYA A;  4Z5Y A;  3LVZ A;  2FHX B;  4FEK A;  4C1D A;  5ACS A;  3ADR A;  2YNT B;  4TZE A;  3SBL A;  5EHT A;  3FAI A;  5KIK A;  2QIN A;  3X2Z A;  4BZ3 A;  4PDX A;  2QED A;  5ACX A;  1X8I A;  2FK6 A;  3IDZ A;  2YHE A;  2I7X A;  2GKL A;  1KO2 A;  1DD6 A;  1WW1 A;  4V0H A;  2FU7 A;  2WYL A;  3Q6V A;  4Z60 A;  3I15 A;  4AXH A;  3IEK A;  2I7T A;  1K07 A;  2Q42 A;  4C1H A;  3AJ3 A;  5LCF A;  2ZZI A;  2GFJ A;  3BK2 A;  5ACU A;  3FCZ A;  4RM5 A;  5AIJ A;  1MQO A;  4C1C A;  5K0W A;  4Z67 A;  4AWZ A;  2XR1 A;  4UWS B;  1VJN A;  2WRS A;  2VW8 A;  5A0V A;  3AF5 A;  4NQ4 A;  3TP9 A;  5LMC A;  3RKJ A;  4FR7 A;  2BG6 A;  2ZO4 A;  4TZB A;  4HKY A;  4D02 A;  2Q0I A;  2P97 A;  3S0Z A;  5FQB A;  2YNV A;  1WUP A;  5ACT A;  5LLD A;  4NUR A;  3JXP A;  4DIK A;  1VGN A;  4TYF A;  5HH6 A;  2YNU A;  3X2Y A;  2I7V A;  3R2U A;  5LS3 A;  3DH8 A;  2UYX A;  1ZNB A;  2M5C A;  3IE0 A;  4HL2 A;  4Z5Z A;  1JJE A;  5LM6 A;  4UWO B;  5LCH A;  5K4K A;  3DHA A;  2CFU A;  2QDT A;  5KIL A;  5A0T A;  3QH8 A;  4AD9 A;  4AV7 A;  4GCW A;  3SRX A;  3X30 A;  2CFZ A;  2YZ3 A;  2BG2 A;  2A7M A;  5DPX A;  5ACW A;  4EXY A;  3I0V A;  5A5Z A;  5IQK A;  1SML A;  2BFZ B;  5EV6 A;  4NQ5 A;  2HB9 A;  4U4L A;  4EFZ A;  2BIB A;  1ZKP A;  4P62 A;  4HL1 A;  5B3R A;  4TYT A;  3IE1 A;  2WYM A;  2Y8A A;  2DOO A;  3IEL A;  5K4N A;  2WYM C;  4C1F A;  3SPU A;  5EVB A;  3T3N A;  5LCA A;  1E5D A;  3KNS A;  2XF4 A;  3BV6 A;  4XWT A;  4WD6 A;  4ZO2 A;  3L6N A;  2GCU A;  4NQ6 A;  2R2D A;  1WUO A;  4D1W A;  3WXC A;  4B87 A;  4D1T A;  3RKK A;  2AIO A;  2NYP A;  3A4Y A;  4EYL A;  4YSL A;  3ZWF A;  5EH9 A;  5HIS A;  3I13 A;  3SD9 A;  3SW3 A;  5ACV A;  4RAM A;  4C1G A;  2BG8 A;  4AX1 B;  3AF6 A;  4XWW A;  5ACP A;  2FU8 A;  2BMI A;  2YNW A;  4GYQ A;  5HIP A; 
#chains in the Genus database with same CATH homology
 5AXR A;  2BTN A;  3PG4 A;  1HLK A;  1WRA A;  1X8G A;  4RL2 A;  4ZO3 A;  1QH5 A;  5AXO A;  4J5F A;  4C09 A;  2YNV B;  4H0D A;  4RL0 A;  1YCF A;  4EYB A;  3SFP A;  4XUK A;  2WHG A;  1XTO A;  4DIL A;  2P18 A;  4KEP A;  2FHX A;  5B15 A;  3F9O A;  1M2X A;  4F6H A;  4RAW A;  2YNT A;  3IOG A;  2FM6 A;  3G1P A;  2BGA A;  3DHC A;  3IOF A;  4YSK A;  1ZTC A;  2DKF A;  2FU6 A;  2OHI A;  5HH4 A;  2GMN A;  1YCH A;  2OHJ A;  1L9Y A;  5FQA A;  4EXS A;  3KL7 A;  4BP0 A;  5ACQ A;  2NZE A;  1JJT A;  1VME A;  4KEQ A;  2CBN A;  1DDK A;  4C1E A;  3VPE A;  1BC2 A;  5EVK A;  4UA4 A;  3ZR9 A;  5A87 A;  2NXA A;  1BVT A;  3IE2 A;  3I11 A;  2QDS A;  3VQZ A;  5AHO A;  1JT1 A;  3DHB A;  4D1U A;  3IEM A;  5K4M A;  4Z7R A;  4AWY B;  4LE6 A;  5HIQ A;  3P2U A;  4UBQ A;  2ZWR A;  4YSB A;  2BG7 A;  5B1U A;  2BFK A;  4GYU A;  2BFL A;  2OHH A;  4CHL A;  2M5D A;  2Q9U A;  4ZNB A;  3PY6 A;  4Z6X A;  4ZEJ A;  2E7Y A;  1P9E A;  4D1V A;  1KR3 A;  2ZNB A;  5FQC A;  4NQ2 A;  4PVO A;  3ESH A;  5HH5 A;  5ACR A;  5LSC A;  5EW0 A;  4JO0 A;  4O98 A;  2Y87 A;  5EVD A;  1X8H A;  2BG8 B;  2Q0J A;  2Y8B A;  5EWA A;  4UWR B;  4RBS A;  3PY5 A;  2P4Z A;  3X2X A;  1DXK A;  5HIO A;  3BC2 A;  2FU9 A;  1BMC A;  2BR6 A;  4EY2 A;  5EV8 A;  3BK1 A;  3KNR A;  5AEB A;  2AZ4 A;  2NZF A;  3T3O A;  2BFZ A;  4EYF A;  2BC2 A;  2P1E A;  3H3E A;  1KO3 A;  4F6Z A;  1A7T A;  3MD7 A;  4UWP B;  4AX0 B;  4UAM A;  5LE1 A;  2YCB A;  2GFK A;  1A8T A;  1YCG A;  1XM8 A;  3ZNB A;  4PVT A;  1Y44 A;  1QH3 A;  3T9M A;  4J5H A;  4TZ9 A;  4FSB A;  2QJS A;  3RPC A;  2H6A A;  3ZQ4 A;  4TZF A;  3I14 A;  5AHR A;  5AYA A;  4Z5Y A;  3LVZ A;  2FHX B;  4FEK A;  4C1D A;  5ACS A;  3ADR A;  2YNT B;  4TZE A;  3SBL A;  5EHT A;  3FAI A;  5KIK A;  2QIN A;  3X2Z A;  4BZ3 A;  2QED A;  5ACX A;  1X8I A;  2FK6 A;  3IDZ A;  2I7X A;  2GKL A;  1KO2 A;  1DD6 A;  1WW1 A;  4V0H A;  2FU7 A;  2WYL A;  3Q6V A;  4Z60 A;  3I15 A;  3IEK A;  2I7T A;  1K07 A;  2Q42 A;  4C1H A;  3AJ3 A;  5LCF A;  2ZZI A;  2GFJ A;  3BK2 A;  5ACU A;  3FCZ A;  4RM5 A;  1MQO A;  4C1C A;  5K0W A;  4Z67 A;  4AWZ A;  2XR1 A;  4UWS B;  1VJN A;  2WRS A;  2VW8 A;  5A0V A;  3AF5 A;  4NQ4 A;  3TP9 A;  5LMC A;  3RKJ A;  4FR7 A;  2BG6 A;  2ZO4 A;  4TZB A;  4HKY A;  4D02 A;  2Q0I A;  2P97 A;  3S0Z A;  5FQB A;  2YNV A;  1WUP A;  5ACT A;  5LLD A;  3JXP A;  4DIK A;  1VGN A;  4TYF A;  5HH6 A;  2YNU A;  3X2Y A;  2I7V A;  3R2U A;  5LS3 A;  3DH8 A;  2UYX A;  1ZNB A;  2M5C A;  3IE0 A;  4HL2 A;  4Z5Z A;  1JJE A;  5LM6 A;  4UWO B;  5LCH A;  5K4K A;  3DHA A;  2QDT A;  5KIL A;  5A0T A;  3QH8 A;  4AD9 A;  4GCW A;  3SRX A;  3X30 A;  2YZ3 A;  2BG2 A;  2A7M A;  5DPX A;  5ACW A;  4EXY A;  3I0V A;  5A5Z A;  5IQK A;  1SML A;  2BFZ B;  5EV6 A;  4NQ5 A;  2HB9 A;  4U4L A;  4EFZ A;  2BIB A;  1ZKP A;  4P62 A;  4HL1 A;  5B3R A;  4TYT A;  3IE1 A;  2WYM A;  2Y8A A;  2DOO A;  3IEL A;  5K4N A;  2WYM C;  4C1F A;  3SPU A;  5EVB A;  3T3N A;  5LCA A;  1E5D A;  3KNS A;  2XF4 A;  3BV6 A;  4XWT A;  4WD6 A;  4ZO2 A;  3L6N A;  2GCU A;  4NQ6 A;  2R2D A;  1WUO A;  4D1W A;  3WXC A;  4B87 A;  4D1T A;  3RKK A;  2AIO A;  2NYP A;  3A4Y A;  4EYL A;  4YSL A;  3ZWF A;  5EH9 A;  5HIS A;  3I13 A;  3SD9 A;  3SW3 A;  5ACV A;  4RAM A;  4C1G A;  2BG8 A;  4AX1 B;  3AF6 A;  4XWW A;  5ACP A;  2FU8 A;  2BMI A;  2YNW A;  4GYQ A;  5HIP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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