5A5ZA

Approved drugs containing thiols as inhibitors of metallo-beta- lactamases: strategy to combat multidrug-resistant bacteria
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
236
structure length
236
Chain Sequence
QQMETGDQRFGDLVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLRLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords BETA-LACTAMASE NDM-1
publication title Approved Drugs Containing Thiols as Inhibitors of Metallo-beta-lactamases: Strategy To Combat Multidrug-Resistant Bacteria.
pubmed doi rcsb
source organism Klebsiella pneumoniae
molecule tags Hydrolase
total genus 80
structure length 236
sequence length 236
chains with identical sequence C
ec nomenclature ec 3.5.2.6: Beta-lactamase.
pdb deposition date 2015-06-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5a5zA00
1JJEA 3SD9A 5ACXA 3IE2A 4YSBA 2HB9A 4UWOB 2XR1A 4Z67A 5KILA 1YCFA 1WW1A 2P18A 5AYAA 4XWWA 5K4NA 1BC2A 4TZFA 3AJ3A 4HL2A 4F6HA 5K4KA 4J5HA 5ACWA 5ACUA 2BFZA 3X2XA 3IDZA 4O98A 3I13A 3WXCA 2YNVB 1WUPA 1A8TA 1M2XA 2ZZIA 2M5DA 3IEMA 4LE6A 3H3EA 4AWYB 2FM6A 2WYMA 2YNWA 2BG8A 2OHIA 1JT1A 4FSBA 2AZ4A 4J5FA 5HH5A 4DIKA 3ADRA 2YZ3A 5LE1A 3S0ZA 1SMLA 5EWAA 2BG2A 3LVZA 2ZO4A 3SRXA 3PY6A 4TZEA 3BC2A 5HIQA 3P2UA 5HIPA 1X8GA 4P62A 3VPEA 2BFZB 3KL7A 5LCFA 5EVBA 3I15A 4D02A 5HISA 4EYFA 4EYLA 2VW8A 2DOOA 5B1UA 5LLDA 4U4LA 3A4YA 4EFZA 4FEKA 2BG8B 1ZNBA 4C1FA 3T3OA 2ZNBA 4KEPA 5FQBA 2FK6A 2CBNA 4ZEJA 4YSLA 3SFPA 5HH4A 5EV6A 3RPCA 5EH9A 5DPXA 3PG4A 5B3RA 4ZO3A 4HL1A 3T9MA 2ZWRA 4RBSA 4C1CA 1JJTA 3IEKA 5A5ZA 4C1EA 4UWRB 5AHOA 1VGNA 4Z60A 3SW3A 2NYPA 2I7TA 2QDTA 2WRSA 4UBQA 5AXRA 4TZBA 2YCBA 5ACRA 5HIOA 4NQ2A 3VQZA 2Y8BA 3X2ZA 1ZKPA 4C1HA 5EVDA 3T3NA 5ACQA 4EXYA 2NZEA 2FHXB 3AF6A 1ZTCA 1X8IA 5B15A 4PVOA 2FU6A 4AWZA 4RM5A 1MQOA 2XF4A 3X30A 3BV6A 3ZWFA 4BP0A 4RL0A 5A0TA 4RAMA 4D1TA 4V0HA 1VMEA 4EYBA 2P4ZA 4TYTA 2YNUA 5ACPA 4NQ5A 2BR6A 5EW0A 4CHLA 4ZNBA 4UAMA 3IE1A 2OHJA 4ZO2A 4XWTA 2P1EA 4Z5ZA 3SBLA 3ZR9A 1DDKA 2I7VA 3IELA 2WHGA 4TZ9A 4EXSA 1X8HA 4D1VA 3IOGA 4RL2A 1WUOA 4AX1B 4Z6XA 4UWSB 2Q42A 1DD6A 2BG7A 5LM6A 1YCGA 5LCAA 4TYFA 1KO2A 3KNRA 1E5DA 5KIKA 2BMIA 2GMNA 4UA4A 3IOFA 2AIOA 3RKJA 1HLKA 3FCZA 3BK2A 1Y44A 2WYLA 3BK1A 1P9EA 1A7TA 5ACSA 2NXAA 3JXPA 4YSKA 3I0VA 3G1PA 5A0VA 2BC2A 2YNTA 3X2YA 4NQ6A 2BIBA 3QH8A 2E7YA 2FU8A 1L9YA 3FAIA 5EVKA 1DXKA 5EHTA 2QINA 5HH6A 4GCWA 4H0DA 4PVTA 4F6ZA 2NZFA 3I11A 3ZQ4A 2Q0JA 5FQAA 3I14A 4B87A 1KO3A 2OHHA 2Y87A 3MD7A 2Q9UA 3DHCA 1QH5A 1WRAA 5ACTA 3SPUA 5K4MA 3KNSA 3F9OA 1K07A 2WYMC 2M5CA 5FQCA 4Z7RA 4GYUA 2BG6A 3ESHA 2FU9A 2BGAA 5LMCA 3DH8A 2BFKA 1XTOA 4GYQA 5IQKA 5ACVA 2GFJA 4HKYA 3Q6VA 3AF5A 5AHRA 2H6AA 2I7XA 2A7MA 2QDSA 4JO0A 2DKFA 3RKKA 4BZ3A 5LSCA 4C1GA 3TP9A 2YNTB 2GKLA 4KEQA 5AEBA 1KR3A 2Y8AA 5AXOA 4D1UA 3L6NA 1BMCA 2BTNA 4C09A 4AD9A 2QJSA 4EY2A 4DILA 2FU7A 4NQ4A 3IE0A 1YCHA 5EV8A 2BFLA 4UWPB 2QEDA 1VJNA 1BVTA 2P97A 2Q0IA 2UYXA 2R2DA 5K0WA 5A87A 4Z5YA 4D1WA 4XUKA 3PY5A 2GFKA 4AX0B 2FHXA 4FR7A 4RAWA 2GCUA 5LCHA 1QH3A 4WD6A 3DHBA 5LS3A 2YNVA 3DHAA 4C1DA 3ZNBA 3R2UA 1XM8A
chains in the Genus database with same CATH superfamily
1JJEA 3SD9A 5ACXA 3IE2A 4YSBA 2HB9A 4UWOB 2XR1A 4Z67A 5KILA 1YCFA 1WW1A 2P18A 5AYAA 4XWWA 5K4NA 1BC2A 4TZFA 3AJ3A 4HL2A 4F6HA 5K4KA 4J5HA 5ACWA 5ACUA 2BFZA 3X2XA 3IDZA 2CFUA 4O98A 3I13A 3WXCA 2YNVB 1WUPA 1A8TA 1M2XA 2ZZIA 2M5DA 3IEMA 4LE6A 3H3EA 4AWYB 2FM6A 2WYMA 2YNWA 2BG8A 2OHIA 1JT1A 4FSBA 2AZ4A 4PDXA 4J5FA 5HH5A 4DIKA 3ADRA 2YZ3A 5LE1A 3S0ZA 5A23A 1SMLA 5EWAA 2BG2A 3LVZA 2ZO4A 3SRXA 3PY6A 4TZEA 3BC2A 5AJLA 5HIQA 3P2UA 5HIPA 1X8GA 4P62A 3VPEA 2BFZB 3KL7A 5LCFA 5EVBA 3I15A 4D02A 5HISA 4EYFA 4EYLA 2VW8A 2DOOA 5B1UA 5LLDA 4U4LA 3A4YA 4EFZA 4FEKA 2BG8B 1ZNBA 4C1FA 3T3OA 2ZNBA 4KEPA 5FQBA 4AV7A 2FK6A 2CBNA 4ZEJA 4YSLA 3SFPA 5HH4A 5EV6A 3RPCA 5EH9A 5DPXA 3PG4A 5B3RA 4ZO3A 4HL1A 3T9MA 2CFZA 2ZWRA 4RBSA 4C1CA 1JJTA 3IEKA 5A5ZA 4C1EA 4UWRB 2YHEA 5AHOA 1VGNA 4Z60A 3SW3A 2NYPA 2I7TA 2QDTA 2WRSA 4UBQA 5AXRA 4TZBA 2YCBA 5ACRA 5HIOA 2CG2A 4NQ2A 3VQZA 2Y8BA 3X2ZA 1ZKPA 4C1HA 5EVDA 3T3NA 5ACQA 4EXYA 2NZEA 2FHXB 3AF6A 1ZTCA 1X8IA 5B15A 4PVOA 2FU6A 4AWZA 4RM5A 1MQOA 2XF4A 3X30A 3BV6A 3ZWFA 4BP0A 4RL0A 5A0TA 4RAMA 4D1TA 4V0HA 1VMEA 4EYBA 2P4ZA 4TYTA 2YNUA 5ACPA 4NQ5A 2BR6A 5EW0A 4CHLA 4ZNBA 4UAMA 3IE1A 2OHJA 4ZO2A 4XWTA 2P1EA 4Z5ZA 3SBLA 3ZR9A 1DDKA 2I7VA 3IELA 2WHGA 4TZ9A 4EXSA 1X8HA 4D1VA 3IOGA 4RL2A 1WUOA 4AX1B 4Z6XA 4UWSB 2Q42A 1DD6A 2BG7A 5LM6A 1YCGA 5LCAA 4TYFA 1KO2A 3KNRA 1E5DA 5KIKA 2BMIA 2GMNA 4UA4A 3IOFA 2AIOA 3RKJA 1HLKA 3FCZA 3BK2A 1Y44A 2CG3A 2WYLA 3BK1A 1P9EA 1A7TA 5ACSA 2NXAA 3JXPA 4YSKA 3I0VA 3G1PA 5A0VA 2BC2A 2YNTA 3X2YA 4NQ6A 2BIBA 3QH8A 2E7YA 2FU8A 1L9YA 3FAIA 5EVKA 1DXKA 5EHTA 2QINA 5HH6A 4GCWA 4H0DA 4PVTA 4F6ZA 2NZFA 3I11A 3ZQ4A 2Q0JA 5FQAA 3I14A 4B87A 1KO3A 2OHHA 2Y87A 3MD7A 2Q9UA 3DHCA 1QH5A 1WRAA 5ACTA 3SPUA 5K4MA 3KNSA 3F9OA 1K07A 2WYMC 2M5CA 5FQCA 4NURA 4GYUA 4Z7RA 2BG6A 3ESHA 2FU9A 2BGAA 5LMCA 3DH8A 2BFKA 1XTOA 4GYQA 5IQKA 5ACVA 2GFJA 4HKYA 3Q6VA 3AF5A 5AHRA 2H6AA 2I7XA 2A7MA 2QDSA 4JO0A 2DKFA 3RKKA 4BZ3A 5LSCA 4C1GA 3TP9A 2YNTB 2GKLA 4KEQA 5AEBA 1KR3A 2Y8AA 5AXOA 4D1UA 5AIJA 3L6NA 1BMCA 4AXHA 2BTNA 4C09A 4AD9A 2QJSA 4EY2A 4DILA 2FU7A 4NQ4A 3IE0A 1YCHA 5EV8A 2BFLA 4UWPB 2QEDA 1VJNA 1BVTA 2P97A 2Q0IA 2UYXA 2R2DA 5K0WA 5A87A 4Z5YA 4D1WA 4XUKA 3PY5A 2GFKA 4AX0B 2FHXA 4FR7A 4RAWA 2GCUA 5LCHA 1QH3A 4WD6A 3DHBA 5LS3A 2YNVA 3DHAA 4C1DA 3ZNBA 3R2UA 1XM8A
chains in the Genus database with same CATH topology
1JJEA 3SD9A 5ACXA 3IE2A 4YSBA 2HB9A 4UWOB 2XR1A 4Z67A 5KILA 1YCFA 1WW1A 2P18A 5AYAA 4XWWA 5K4NA 1BC2A 4TZFA 3AJ3A 4HL2A 4F6HA 5K4KA 4J5HA 5ACWA 5ACUA 2BFZA 3X2XA 3IDZA 4O98A 3I13A 3WXCA 2YNVB 1WUPA 1A8TA 1M2XA 2ZZIA 2M5DA 3IEMA 4LE6A 3H3EA 4AWYB 2FM6A 2WYMA 2YNWA 2BG8A 2OHIA 1JT1A 4FSBA 2AZ4A 4J5FA 5HH5A 4DIKA 3ADRA 2YZ3A 5LE1A 3S0ZA 1SMLA 5EWAA 2BG2A 3LVZA 2ZO4A 3SRXA 3PY6A 4TZEA 3BC2A 5HIQA 3P2UA 5HIPA 1X8GA 4P62A 3VPEA 2BFZB 3KL7A 5LCFA 5EVBA 3I15A 4D02A 5HISA 4EYFA 4EYLA 2VW8A 2DOOA 5B1UA 5LLDA 4U4LA 3A4YA 4EFZA 4FEKA 2BG8B 1ZNBA 4C1FA 3T3OA 2ZNBA 4KEPA 5FQBA 2FK6A 2CBNA 4ZEJA 4YSLA 3SFPA 5HH4A 5EV6A 3RPCA 5EH9A 5DPXA 3PG4A 5B3RA 4ZO3A 4HL1A 3T9MA 2ZWRA 4RBSA 4C1CA 1JJTA 3IEKA 5A5ZA 4C1EA 4UWRB 5AHOA 1VGNA 4Z60A 3SW3A 2NYPA 2I7TA 2QDTA 2WRSA 4UBQA 5AXRA 4TZBA 2YCBA 5ACRA 5HIOA 4NQ2A 3VQZA 2Y8BA 3X2ZA 1ZKPA 4C1HA 5EVDA 3T3NA 5ACQA 4EXYA 2NZEA 2FHXB 3AF6A 1ZTCA 1X8IA 5B15A 4PVOA 2FU6A 4AWZA 4RM5A 1MQOA 2XF4A 3X30A 3BV6A 3ZWFA 4BP0A 4RL0A 5A0TA 4RAMA 4D1TA 4V0HA 1VMEA 4EYBA 2P4ZA 4TYTA 2YNUA 5ACPA 4NQ5A 2BR6A 5EW0A 4CHLA 4ZNBA 4UAMA 3IE1A 2OHJA 4ZO2A 4XWTA 2P1EA 4Z5ZA 3SBLA 3ZR9A 1DDKA 2I7VA 3IELA 2WHGA 4TZ9A 4EXSA 1X8HA 4D1VA 3IOGA 4RL2A 1WUOA 4AX1B 4Z6XA 4UWSB 2Q42A 1DD6A 2BG7A 5LM6A 1YCGA 5LCAA 4TYFA 1KO2A 3KNRA 1E5DA 5KIKA 2BMIA 2GMNA 4UA4A 3IOFA 2AIOA 3RKJA 1HLKA 3FCZA 3BK2A 1Y44A 2WYLA 3BK1A 1P9EA 1A7TA 5ACSA 2NXAA 3JXPA 4YSKA 3I0VA 3G1PA 5A0VA 2BC2A 2YNTA 3X2YA 4NQ6A 2BIBA 3QH8A 2E7YA 2FU8A 1L9YA 3FAIA 5EVKA 1DXKA 5EHTA 2QINA 5HH6A 4GCWA 4H0DA 4PVTA 4F6ZA 2NZFA 3I11A 3ZQ4A 2Q0JA 5FQAA 3I14A 4B87A 1KO3A 2OHHA 2Y87A 3MD7A 2Q9UA 3DHCA 1QH5A 1WRAA 5ACTA 3SPUA 5K4MA 3KNSA 3F9OA 1K07A 2WYMC 2M5CA 5FQCA 4Z7RA 4GYUA 2BG6A 3ESHA 2FU9A 2BGAA 5LMCA 3DH8A 2BFKA 1XTOA 4GYQA 5IQKA 5ACVA 2GFJA 4HKYA 3Q6VA 3AF5A 5AHRA 2H6AA 2I7XA 2A7MA 2QDSA 4JO0A 2DKFA 3RKKA 4BZ3A 5LSCA 4C1GA 3TP9A 2YNTB 2GKLA 4KEQA 5AEBA 1KR3A 2Y8AA 5AXOA 4D1UA 3L6NA 1BMCA 2BTNA 4C09A 4AD9A 2QJSA 4EY2A 4DILA 2FU7A 4NQ4A 3IE0A 1YCHA 5EV8A 2BFLA 4UWPB 2QEDA 1VJNA 1BVTA 2P97A 2Q0IA 2UYXA 2R2DA 5K0WA 5A87A 4Z5YA 4D1WA 4XUKA 3PY5A 2GFKA 4AX0B 2FHXA 4FR7A 4RAWA 2GCUA 5LCHA 1QH3A 4WD6A 3DHBA 5LS3A 2YNVA 3DHAA 4C1DA 3ZNBA 3R2UA 1XM8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JJE A;  3SD9 A;  5ACX A;  3IE2 A;  4YSB A;  2HB9 A;  4UWO B;  2XR1 A;  4Z67 A;  5KIL A;  1YCF A;  1WW1 A;  2P18 A;  5AYA A;  4XWW A;  5K4N A;  1BC2 A;  4TZF A;  3AJ3 A;  4HL2 A;  4F6H A;  5K4K A;  4J5H A;  5ACW A;  5ACU A;  2BFZ A;  3X2X A;  3IDZ A;  4O98 A;  3I13 A;  3WXC A;  2YNV B;  1WUP A;  1A8T A;  1M2X A;  2ZZI A;  2M5D A;  3IEM A;  4LE6 A;  3H3E A;  4AWY B;  2FM6 A;  2WYM A;  2YNW A;  2BG8 A;  2OHI A;  1JT1 A;  4FSB A;  2AZ4 A;  4J5F A;  5HH5 A;  4DIK A;  3ADR A;  2YZ3 A;  5LE1 A;  3S0Z A;  1SML A;  5EWA A;  2BG2 A;  3LVZ A;  2ZO4 A;  3SRX A;  3PY6 A;  4TZE A;  3BC2 A;  5HIQ A;  3P2U A;  5HIP A;  1X8G A;  4P62 A;  3VPE A;  2BFZ B;  3KL7 A;  5LCF A;  5EVB A;  3I15 A;  4D02 A;  5HIS A;  4EYF A;  4EYL A;  2VW8 A;  2DOO A;  5B1U A;  5LLD A;  4U4L A;  3A4Y A;  4EFZ A;  4FEK A;  2BG8 B;  1ZNB A;  4C1F A;  3T3O A;  2ZNB A;  4KEP A;  5FQB A;  2FK6 A;  2CBN A;  4ZEJ A;  4YSL A;  3SFP A;  5HH4 A;  5EV6 A;  3RPC A;  5EH9 A;  5DPX A;  3PG4 A;  5B3R A;  4ZO3 A;  4HL1 A;  3T9M A;  2ZWR A;  4RBS A;  4C1C A;  1JJT A;  3IEK A;  5A5Z A;  4C1E A;  4UWR B;  5AHO A;  1VGN A;  4Z60 A;  3SW3 A;  2NYP A;  2I7T A;  2QDT A;  2WRS A;  4UBQ A;  5AXR A;  4TZB A;  2YCB A;  5ACR A;  5HIO A;  4NQ2 A;  3VQZ A;  2Y8B A;  3X2Z A;  1ZKP A;  4C1H A;  5EVD A;  3T3N A;  5ACQ A;  4EXY A;  2NZE A;  2FHX B;  3AF6 A;  1ZTC A;  1X8I A;  5B15 A;  4PVO A;  2FU6 A;  4AWZ A;  4RM5 A;  1MQO A;  2XF4 A;  3X30 A;  3BV6 A;  3ZWF A;  4BP0 A;  4RL0 A;  5A0T A;  4RAM A;  4D1T A;  4V0H A;  1VME A;  4EYB A;  2P4Z A;  4TYT A;  2YNU A;  5ACP A;  4NQ5 A;  2BR6 A;  5EW0 A;  4CHL A;  4ZNB A;  4UAM A;  3IE1 A;  2OHJ A;  4ZO2 A;  4XWT A;  2P1E A;  4Z5Z A;  3SBL A;  3ZR9 A;  1DDK A;  2I7V A;  3IEL A;  2WHG A;  4TZ9 A;  4EXS A;  1X8H A;  4D1V A;  3IOG A;  4RL2 A;  1WUO A;  4AX1 B;  4Z6X A;  4UWS B;  2Q42 A;  1DD6 A;  2BG7 A;  5LM6 A;  1YCG A;  5LCA A;  4TYF A;  1KO2 A;  3KNR A;  1E5D A;  5KIK A;  2BMI A;  2GMN A;  4UA4 A;  3IOF A;  2AIO A;  3RKJ A;  1HLK A;  3FCZ A;  3BK2 A;  1Y44 A;  2WYL A;  3BK1 A;  1P9E A;  1A7T A;  5ACS A;  2NXA A;  3JXP A;  4YSK A;  3I0V A;  3G1P A;  5A0V A;  2BC2 A;  2YNT A;  3X2Y A;  4NQ6 A;  2BIB A;  3QH8 A;  2E7Y A;  2FU8 A;  1L9Y A;  3FAI A;  5EVK A;  1DXK A;  5EHT A;  2QIN A;  5HH6 A;  4GCW A;  4H0D A;  4PVT A;  4F6Z A;  2NZF A;  3I11 A;  3ZQ4 A;  2Q0J A;  5FQA A;  3I14 A;  4B87 A;  1KO3 A;  2OHH A;  2Y87 A;  3MD7 A;  2Q9U A;  3DHC A;  1QH5 A;  1WRA A;  5ACT A;  3SPU A;  5K4M A;  3KNS A;  3F9O A;  1K07 A;  2WYM C;  2M5C A;  5FQC A;  4Z7R A;  4GYU A;  2BG6 A;  3ESH A;  2FU9 A;  2BGA A;  5LMC A;  3DH8 A;  2BFK A;  1XTO A;  4GYQ A;  5IQK A;  5ACV A;  2GFJ A;  4HKY A;  3Q6V A;  3AF5 A;  5AHR A;  2H6A A;  2I7X A;  2A7M A;  2QDS A;  4JO0 A;  2DKF A;  3RKK A;  4BZ3 A;  5LSC A;  4C1G A;  3TP9 A;  2YNT B;  2GKL A;  4KEQ A;  5AEB A;  1KR3 A;  2Y8A A;  5AXO A;  4D1U A;  3L6N A;  1BMC A;  2BTN A;  4C09 A;  4AD9 A;  2QJS A;  4EY2 A;  4DIL A;  2FU7 A;  4NQ4 A;  3IE0 A;  1YCH A;  5EV8 A;  2BFL A;  4UWP B;  2QED A;  1VJN A;  1BVT A;  2P97 A;  2Q0I A;  2UYX A;  2R2D A;  5K0W A;  5A87 A;  4Z5Y A;  4D1W A;  4XUK A;  3PY5 A;  2GFK A;  4AX0 B;  2FHX A;  4FR7 A;  4RAW A;  2GCU A;  5LCH A;  1QH3 A;  4WD6 A;  3DHB A;  5LS3 A;  2YNV A;  3DHA A;  4C1D A;  3ZNB A;  3R2U A;  1XM8 A; 
#chains in the Genus database with same CATH topology
 1JJE A;  3SD9 A;  5ACX A;  3IE2 A;  4YSB A;  2HB9 A;  4UWO B;  2XR1 A;  4Z67 A;  5KIL A;  1YCF A;  1WW1 A;  2P18 A;  5AYA A;  4XWW A;  5K4N A;  1BC2 A;  4TZF A;  3AJ3 A;  4HL2 A;  4F6H A;  5K4K A;  4J5H A;  5ACW A;  5ACU A;  2BFZ A;  3X2X A;  3IDZ A;  2CFU A;  4O98 A;  3I13 A;  3WXC A;  2YNV B;  1WUP A;  1A8T A;  1M2X A;  2ZZI A;  2M5D A;  3IEM A;  4LE6 A;  3H3E A;  4AWY B;  2FM6 A;  2WYM A;  2YNW A;  2BG8 A;  2OHI A;  1JT1 A;  4FSB A;  2AZ4 A;  4PDX A;  4J5F A;  5HH5 A;  4DIK A;  3ADR A;  2YZ3 A;  5LE1 A;  3S0Z A;  5A23 A;  1SML A;  5EWA A;  2BG2 A;  3LVZ A;  2ZO4 A;  3SRX A;  3PY6 A;  4TZE A;  3BC2 A;  5AJL A;  5HIQ A;  3P2U A;  5HIP A;  1X8G A;  4P62 A;  3VPE A;  2BFZ B;  3KL7 A;  5LCF A;  5EVB A;  3I15 A;  4D02 A;  5HIS A;  4EYF A;  4EYL A;  2VW8 A;  2DOO A;  5B1U A;  5LLD A;  4U4L A;  3A4Y A;  4EFZ A;  4FEK A;  2BG8 B;  1ZNB A;  4C1F A;  3T3O A;  2ZNB A;  4KEP A;  5FQB A;  4AV7 A;  2FK6 A;  2CBN A;  4ZEJ A;  4YSL A;  3SFP A;  5HH4 A;  5EV6 A;  3RPC A;  5EH9 A;  5DPX A;  3PG4 A;  5B3R A;  4ZO3 A;  4HL1 A;  3T9M A;  2CFZ A;  2ZWR A;  4RBS A;  4C1C A;  1JJT A;  3IEK A;  5A5Z A;  4C1E A;  4UWR B;  2YHE A;  5AHO A;  1VGN A;  4Z60 A;  3SW3 A;  2NYP A;  2I7T A;  2QDT A;  2WRS A;  4UBQ A;  5AXR A;  4TZB A;  2YCB A;  5ACR A;  5HIO A;  2CG2 A;  4NQ2 A;  3VQZ A;  2Y8B A;  3X2Z A;  1ZKP A;  4C1H A;  5EVD A;  3T3N A;  5ACQ A;  4EXY A;  2NZE A;  2FHX B;  3AF6 A;  1ZTC A;  1X8I A;  5B15 A;  4PVO A;  2FU6 A;  4AWZ A;  4RM5 A;  1MQO A;  2XF4 A;  3X30 A;  3BV6 A;  3ZWF A;  4BP0 A;  4RL0 A;  5A0T A;  4RAM A;  4D1T A;  4V0H A;  1VME A;  4EYB A;  2P4Z A;  4TYT A;  2YNU A;  5ACP A;  4NQ5 A;  2BR6 A;  5EW0 A;  4CHL A;  4ZNB A;  4UAM A;  3IE1 A;  2OHJ A;  4ZO2 A;  4XWT A;  2P1E A;  4Z5Z A;  3SBL A;  3ZR9 A;  1DDK A;  2I7V A;  3IEL A;  2WHG A;  4TZ9 A;  4EXS A;  1X8H A;  4D1V A;  3IOG A;  4RL2 A;  1WUO A;  4AX1 B;  4Z6X A;  4UWS B;  2Q42 A;  1DD6 A;  2BG7 A;  5LM6 A;  1YCG A;  5LCA A;  4TYF A;  1KO2 A;  3KNR A;  1E5D A;  5KIK A;  2BMI A;  2GMN A;  4UA4 A;  3IOF A;  2AIO A;  3RKJ A;  1HLK A;  3FCZ A;  3BK2 A;  1Y44 A;  2CG3 A;  2WYL A;  3BK1 A;  1P9E A;  1A7T A;  5ACS A;  2NXA A;  3JXP A;  4YSK A;  3I0V A;  3G1P A;  5A0V A;  2BC2 A;  2YNT A;  3X2Y A;  4NQ6 A;  2BIB A;  3QH8 A;  2E7Y A;  2FU8 A;  1L9Y A;  3FAI A;  5EVK A;  1DXK A;  5EHT A;  2QIN A;  5HH6 A;  4GCW A;  4H0D A;  4PVT A;  4F6Z A;  2NZF A;  3I11 A;  3ZQ4 A;  2Q0J A;  5FQA A;  3I14 A;  4B87 A;  1KO3 A;  2OHH A;  2Y87 A;  3MD7 A;  2Q9U A;  3DHC A;  1QH5 A;  1WRA A;  5ACT A;  3SPU A;  5K4M A;  3KNS A;  3F9O A;  1K07 A;  2WYM C;  2M5C A;  5FQC A;  4NUR A;  4GYU A;  4Z7R A;  2BG6 A;  3ESH A;  2FU9 A;  2BGA A;  5LMC A;  3DH8 A;  2BFK A;  1XTO A;  4GYQ A;  5IQK A;  5ACV A;  2GFJ A;  4HKY A;  3Q6V A;  3AF5 A;  5AHR A;  2H6A A;  2I7X A;  2A7M A;  2QDS A;  4JO0 A;  2DKF A;  3RKK A;  4BZ3 A;  5LSC A;  4C1G A;  3TP9 A;  2YNT B;  2GKL A;  4KEQ A;  5AEB A;  1KR3 A;  2Y8A A;  5AXO A;  4D1U A;  5AIJ A;  3L6N A;  1BMC A;  4AXH A;  2BTN A;  4C09 A;  4AD9 A;  2QJS A;  4EY2 A;  4DIL A;  2FU7 A;  4NQ4 A;  3IE0 A;  1YCH A;  5EV8 A;  2BFL A;  4UWP B;  2QED A;  1VJN A;  1BVT A;  2P97 A;  2Q0I A;  2UYX A;  2R2D A;  5K0W A;  5A87 A;  4Z5Y A;  4D1W A;  4XUK A;  3PY5 A;  2GFK A;  4AX0 B;  2FHX A;  4FR7 A;  4RAW A;  2GCU A;  5LCH A;  1QH3 A;  4WD6 A;  3DHB A;  5LS3 A;  2YNV A;  3DHA A;  4C1D A;  3ZNB A;  3R2U A;  1XM8 A; 
#chains in the Genus database with same CATH homology
 1JJE A;  3SD9 A;  5ACX A;  3IE2 A;  4YSB A;  2HB9 A;  4UWO B;  2XR1 A;  4Z67 A;  5KIL A;  1YCF A;  1WW1 A;  2P18 A;  5AYA A;  4XWW A;  5K4N A;  1BC2 A;  4TZF A;  3AJ3 A;  4HL2 A;  4F6H A;  5K4K A;  4J5H A;  5ACW A;  5ACU A;  2BFZ A;  3X2X A;  3IDZ A;  4O98 A;  3I13 A;  3WXC A;  2YNV B;  1WUP A;  1A8T A;  1M2X A;  2ZZI A;  2M5D A;  3IEM A;  4LE6 A;  3H3E A;  4AWY B;  2FM6 A;  2WYM A;  2YNW A;  2BG8 A;  2OHI A;  1JT1 A;  4FSB A;  2AZ4 A;  4J5F A;  5HH5 A;  4DIK A;  3ADR A;  2YZ3 A;  5LE1 A;  3S0Z A;  1SML A;  5EWA A;  2BG2 A;  3LVZ A;  2ZO4 A;  3SRX A;  3PY6 A;  4TZE A;  3BC2 A;  5HIQ A;  3P2U A;  5HIP A;  1X8G A;  4P62 A;  3VPE A;  2BFZ B;  3KL7 A;  5LCF A;  5EVB A;  3I15 A;  4D02 A;  5HIS A;  4EYF A;  4EYL A;  2VW8 A;  2DOO A;  5B1U A;  5LLD A;  4U4L A;  3A4Y A;  4EFZ A;  4FEK A;  2BG8 B;  1ZNB A;  4C1F A;  3T3O A;  2ZNB A;  4KEP A;  5FQB A;  2FK6 A;  2CBN A;  4ZEJ A;  4YSL A;  3SFP A;  5HH4 A;  5EV6 A;  3RPC A;  5EH9 A;  5DPX A;  3PG4 A;  5B3R A;  4ZO3 A;  4HL1 A;  3T9M A;  2ZWR A;  4RBS A;  4C1C A;  1JJT A;  3IEK A;  5A5Z A;  4C1E A;  4UWR B;  5AHO A;  1VGN A;  4Z60 A;  3SW3 A;  2NYP A;  2I7T A;  2QDT A;  2WRS A;  4UBQ A;  5AXR A;  4TZB A;  2YCB A;  5ACR A;  5HIO A;  4NQ2 A;  3VQZ A;  2Y8B A;  3X2Z A;  1ZKP A;  4C1H A;  5EVD A;  3T3N A;  5ACQ A;  4EXY A;  2NZE A;  2FHX B;  3AF6 A;  1ZTC A;  1X8I A;  5B15 A;  4PVO A;  2FU6 A;  4AWZ A;  4RM5 A;  1MQO A;  2XF4 A;  3X30 A;  3BV6 A;  3ZWF A;  4BP0 A;  4RL0 A;  5A0T A;  4RAM A;  4D1T A;  4V0H A;  1VME A;  4EYB A;  2P4Z A;  4TYT A;  2YNU A;  5ACP A;  4NQ5 A;  2BR6 A;  5EW0 A;  4CHL A;  4ZNB A;  4UAM A;  3IE1 A;  2OHJ A;  4ZO2 A;  4XWT A;  2P1E A;  4Z5Z A;  3SBL A;  3ZR9 A;  1DDK A;  2I7V A;  3IEL A;  2WHG A;  4TZ9 A;  4EXS A;  1X8H A;  4D1V A;  3IOG A;  4RL2 A;  1WUO A;  4AX1 B;  4Z6X A;  4UWS B;  2Q42 A;  1DD6 A;  2BG7 A;  5LM6 A;  1YCG A;  5LCA A;  4TYF A;  1KO2 A;  3KNR A;  1E5D A;  5KIK A;  2BMI A;  2GMN A;  4UA4 A;  3IOF A;  2AIO A;  3RKJ A;  1HLK A;  3FCZ A;  3BK2 A;  1Y44 A;  2WYL A;  3BK1 A;  1P9E A;  1A7T A;  5ACS A;  2NXA A;  3JXP A;  4YSK A;  3I0V A;  3G1P A;  5A0V A;  2BC2 A;  2YNT A;  3X2Y A;  4NQ6 A;  2BIB A;  3QH8 A;  2E7Y A;  2FU8 A;  1L9Y A;  3FAI A;  5EVK A;  1DXK A;  5EHT A;  2QIN A;  5HH6 A;  4GCW A;  4H0D A;  4PVT A;  4F6Z A;  2NZF A;  3I11 A;  3ZQ4 A;  2Q0J A;  5FQA A;  3I14 A;  4B87 A;  1KO3 A;  2OHH A;  2Y87 A;  3MD7 A;  2Q9U A;  3DHC A;  1QH5 A;  1WRA A;  5ACT A;  3SPU A;  5K4M A;  3KNS A;  3F9O A;  1K07 A;  2WYM C;  2M5C A;  5FQC A;  4Z7R A;  4GYU A;  2BG6 A;  3ESH A;  2FU9 A;  2BGA A;  5LMC A;  3DH8 A;  2BFK A;  1XTO A;  4GYQ A;  5IQK A;  5ACV A;  2GFJ A;  4HKY A;  3Q6V A;  3AF5 A;  5AHR A;  2H6A A;  2I7X A;  2A7M A;  2QDS A;  4JO0 A;  2DKF A;  3RKK A;  4BZ3 A;  5LSC A;  4C1G A;  3TP9 A;  2YNT B;  2GKL A;  4KEQ A;  5AEB A;  1KR3 A;  2Y8A A;  5AXO A;  4D1U A;  3L6N A;  1BMC A;  2BTN A;  4C09 A;  4AD9 A;  2QJS A;  4EY2 A;  4DIL A;  2FU7 A;  4NQ4 A;  3IE0 A;  1YCH A;  5EV8 A;  2BFL A;  4UWP B;  2QED A;  1VJN A;  1BVT A;  2P97 A;  2Q0I A;  2UYX A;  2R2D A;  5K0W A;  5A87 A;  4Z5Y A;  4D1W A;  4XUK A;  3PY5 A;  2GFK A;  4AX0 B;  2FHX A;  4FR7 A;  4RAW A;  2GCU A;  5LCH A;  1QH3 A;  4WD6 A;  3DHB A;  5LS3 A;  2YNV A;  3DHA A;  4C1D A;  3ZNB A;  3R2U A;  1XM8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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