5A5ZA

Approved drugs containing thiols as inhibitors of metallo-beta- lactamases: strategy to combat multidrug-resistant bacteria
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
236
structure length
236
Chain Sequence
QQMETGDQRFGDLVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLRLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Approved Drugs Containing Thiols as Inhibitors of Metallo-beta-lactamases: Strategy To Combat Multidrug-Resistant Bacteria.
pubmed doi rcsb
molecule tags Hydrolase
source organism Klebsiella pneumoniae
molecule keywords BETA-LACTAMASE NDM-1
total genus 80
structure length 236
sequence length 236
chains with identical sequence C
ec nomenclature ec 3.5.2.6: Beta-lactamase.
pdb deposition date 2015-06-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5a5zA00
5EWAA 4NQ4A 2FU6A 3PG4A 2GFJA 3MD7A 5LCAA 5AXRA 1X8GA 3T3NA 4UBQA 1QH3A 3ADRA 4HKYA 4JO0A 2I7TA 4AWYB 5LCFA 2WYLA 2FK6A 5EH9A 5B3RA 5ACSA 5LM6A 4UA4A 4ZO3A 5ACWA 3BV6A 2WYMA 4AD9A 1X8HA 5AHRA 4HL2A 3F9OA 2P18A 4RBSA 3AJ3A 4WD6A 5EHTA 4P62A 4GYQA 5LSCA 3IE1A 3ZNBA 2GMNA 2GCUA 3BK2A 2BC2A 5LMCA 1HLKA 3I0VA 1WW1A 2BG2A 2YNUA 5EVBA 1QH5A 1A7TA 2YZ3A 5LS3A 3SPUA 3QH8A 1BMCA 1SMLA 1JT1A 2BFZA 4RAMA 2NXAA 3X2YA 3VQZA 1VJNA 5AXOA 5DPXA 1YCGA 1BVTA 1X8IA 4KEPA 2HB9A 2GKLA 2M5DA 3X2ZA 3G1PA 2WYMC 5ACRA 1JJTA 5EV8A 3Q6VA 5IQKA 2FU9A 2ZNBA 1WUPA 2Q9UA 4U4LA 4TZ9A 2R2DA 3ESHA 2BR6A 5K4MA 3T9MA 5A5ZA 4UAMA 3SRXA 5AHOA 5ACQA 3WXCA 1DXKA 3IDZA 5ACTA 4D02A 1ZNBA 4V0HA 5HH6A 4D1TA 4UWSB 4F6ZA 3IOFA 2A7MA 2DOOA 5ACVA 2QEDA 4Z5YA 5AEBA 2E7YA 3DHCA 5A87A 4UWPB 4EY2A 4TZEA 3AF6A 5EVKA 4PVTA 4EFZA 4HL1A 2BG8B 4NQ5A 2OHIA 2FHXB 2P1EA 4LE6A 2Q42A 2AIOA 2BIBA 1MQOA 5HH4A 3IEKA 5K4NA 4H0DA 3R2UA 3JXPA 2NYPA 1M2XA 2Y87A 3DHAA 5LE1A 4C1CA 4NQ2A 4O98A 3RKKA 2QDTA 1VMEA 3ZR9A 4RAWA 4C1GA 1DD6A 2ZZIA 3SD9A 4C09A 1KO2A 2H6AA 5A0VA 4C1EA 2M5CA 4XUKA 1ZTCA 4GYUA 2CBNA 5HH5A 1VGNA 2FU7A 2UYXA 3IEMA 4BZ3A 4Z7RA 3I14A 3ZWFA 4AX1B 1YCFA 4NQ6A 2VW8A 1K07A 4D1UA 2ZWRA 3FAIA 4GCWA 2BTNA 3H3EA 3I15A 2AZ4A 1JJEA 4DIKA 4TZFA 2NZEA 3BK1A 3IOGA 2WHGA 4RM5A 5EV6A 4UWRB 1Y44A 1ZKPA 5AYAA 5HIOA 3KL7A 3IE0A 3DHBA 4Z6XA 2Y8BA 2XR1A 2YNWA 4FSBA 4KEQA 5HIQA 4TYTA 4TYFA 5ACPA 2YCBA 4AX0B 1WUOA 2BFLA 3S0ZA 4ZNBA 5A0TA 2OHJA 3SW3A 3FCZA 4EYLA 4FR7A 1P9EA 3A4YA 4C1FA 3X30A 5KILA 2QINA 4Z60A 5LCHA 5ACUA 3X2XA 4CHLA 2BFKA 4J5FA 4UWOB 5HIPA 2Y8AA 2Q0IA 5K0WA 4PVOA 4J5HA 5EVDA 2Q0JA 4FEKA 2YNVB 4Z5ZA 1KO3A 2BG7A 1DDKA 5ACXA 3AF5A 4B87A 4D1VA 5KIKA 2ZO4A 2YNTB 3PY5A 3P2UA 4AWZA 2I7XA 4EXYA 2DKFA 3DH8A 1WRAA 3SBLA 4C1DA 4DILA 2P4ZA 2QJSA 3BC2A 3I13A 2BG6A 4RL0A 5LLDA 5B15A 2QDSA 2BMIA 3IELA 3RKJA 3LVZA 4XWTA 2NZFA 4XWWA 3VPEA 1XM8A 5FQBA 4EYBA 3IE2A 3T3OA 3L6NA 4Z67A 4ZO2A 3SFPA 2FU8A 2XF4A 4RL2A 2FM6A 1L9YA 1E5DA 3ZQ4A 3KNRA 1XTOA 4YSBA 4TZBA 3RPCA 3KNSA 5HISA 3PY6A 2BG8A 4F6HA 2BGAA 3I11A 2FHXA 4BP0A 2OHHA 5FQCA 5B1UA 4EXSA 1BC2A 2P97A 4YSKA 4YSLA 4D1WA 4ZEJA 2YNVA 2I7VA 1YCHA 2BFZB 2YNTA 1A8TA 5FQAA 3TP9A 2WRSA 5EW0A 4C1HA 1KR3A 4EYFA 2GFKA 5K4KA
chains in the Genus database with same CATH superfamily
5EWAA 4NQ4A 2FU6A 3PG4A 2GFJA 3MD7A 5LCAA 5AXRA 1X8GA 3T3NA 4UBQA 1QH3A 3ADRA 4HKYA 4JO0A 2I7TA 4AWYB 5LCFA 2WYLA 2FK6A 5EH9A 5B3RA 5ACSA 5LM6A 4UA4A 4ZO3A 5ACWA 3BV6A 2WYMA 4AD9A 1X8HA 5AHRA 4HL2A 3F9OA 2P18A 4RBSA 3AJ3A 4WD6A 5EHTA 4P62A 4GYQA 5LSCA 3IE1A 3ZNBA 2GMNA 2GCUA 3BK2A 2BC2A 5LMCA 1HLKA 3I0VA 1WW1A 2BG2A 2YNUA 5EVBA 1QH5A 1A7TA 2YZ3A 5LS3A 3SPUA 3QH8A 1BMCA 1SMLA 1JT1A 2BFZA 4RAMA 2NXAA 2YHEA 3X2YA 3VQZA 1VJNA 5AXOA 5DPXA 1YCGA 1BVTA 1X8IA 4KEPA 2HB9A 2GKLA 2M5DA 3X2ZA 3G1PA 2WYMC 5ACRA 1JJTA 5EV8A 3Q6VA 5IQKA 2FU9A 2CFZA 2ZNBA 1WUPA 2Q9UA 4U4LA 4TZ9A 2R2DA 3ESHA 2BR6A 5K4MA 3T9MA 5A5ZA 4UAMA 3SRXA 5AHOA 5ACQA 3WXCA 1DXKA 3IDZA 5ACTA 4D02A 1ZNBA 4V0HA 5HH6A 4D1TA 4UWSB 4F6ZA 3IOFA 2A7MA 2DOOA 5ACVA 2QEDA 4Z5YA 5AEBA 2E7YA 3DHCA 5A87A 4UWPB 4EY2A 4TZEA 3AF6A 5EVKA 4PVTA 4EFZA 4HL1A 2BG8B 4NQ5A 2OHIA 2FHXB 2P1EA 4LE6A 2Q42A 2AIOA 2BIBA 1MQOA 5HH4A 3IEKA 5K4NA 4H0DA 3R2UA 3JXPA 2NYPA 4PDXA 1M2XA 2Y87A 3DHAA 5LE1A 4C1CA 4NQ2A 4O98A 3RKKA 2QDTA 4AXHA 1VMEA 3ZR9A 4RAWA 4C1GA 1DD6A 2ZZIA 3SD9A 4C09A 1KO2A 2H6AA 5A0VA 4C1EA 2M5CA 4XUKA 1ZTCA 4GYUA 2CBNA 5HH5A 1VGNA 2FU7A 2UYXA 3IEMA 4BZ3A 4Z7RA 3I14A 3ZWFA 4AX1B 1YCFA 4NQ6A 2VW8A 1K07A 4D1UA 2ZWRA 2CFUA 3FAIA 4GCWA 2BTNA 3H3EA 3I15A 2AZ4A 1JJEA 4DIKA 4TZFA 2NZEA 3BK1A 3IOGA 2WHGA 4RM5A 5EV6A 4UWRB 1Y44A 5AJLA 1ZKPA 5AYAA 5HIOA 3KL7A 3IE0A 3DHBA 4Z6XA 2Y8BA 2XR1A 2YNWA 4FSBA 4KEQA 5HIQA 4TYTA 4TYFA 5ACPA 2YCBA 4AX0B 1WUOA 2BFLA 2CG2A 3S0ZA 4ZNBA 5A0TA 2OHJA 3SW3A 3FCZA 4EYLA 4FR7A 1P9EA 3A4YA 4C1FA 3X30A 5KILA 2QINA 4Z60A 5LCHA 5ACUA 3X2XA 4CHLA 2BFKA 4J5FA 4UWOB 5HIPA 2Y8AA 2Q0IA 5K0WA 4PVOA 4J5HA 5EVDA 2Q0JA 4FEKA 2YNVB 4Z5ZA 1KO3A 2BG7A 1DDKA 5ACXA 3AF5A 4B87A 4D1VA 5KIKA 2ZO4A 2YNTB 3PY5A 3P2UA 4AWZA 2I7XA 2DKFA 3DH8A 4AV7A 1WRAA 4EXYA 3SBLA 4C1DA 4DILA 2P4ZA 2QJSA 3BC2A 3I13A 2BG6A 4NURA 4RL0A 5LLDA 5B15A 2QDSA 2BMIA 3IELA 3RKJA 3LVZA 4XWTA 2NZFA 4XWWA 3VPEA 1XM8A 5FQBA 4EYBA 3IE2A 3T3OA 3L6NA 4Z67A 4ZO2A 3SFPA 2FU8A 2XF4A 4RL2A 2FM6A 1L9YA 5AIJA 1E5DA 3ZQ4A 3KNRA 1XTOA 4YSBA 4TZBA 3RPCA 3KNSA 5HISA 3PY6A 2BG8A 4F6HA 2BGAA 3I11A 2FHXA 5A23A 4BP0A 2OHHA 5FQCA 5B1UA 4EXSA 2CG3A 1BC2A 2P97A 4YSKA 4YSLA 4D1WA 4ZEJA 2YNVA 2I7VA 1YCHA 2BFZB 2YNTA 1A8TA 5FQAA 3TP9A 2WRSA 5EW0A 4C1HA 1KR3A 4EYFA 2GFKA 5K4KA
chains in the Genus database with same CATH topology
5EWAA 4NQ4A 2FU6A 3PG4A 2GFJA 3MD7A 5LCAA 5AXRA 1X8GA 3T3NA 4UBQA 1QH3A 3ADRA 4HKYA 4JO0A 2I7TA 4AWYB 5LCFA 2WYLA 2FK6A 5EH9A 5B3RA 5ACSA 5LM6A 4UA4A 4ZO3A 5ACWA 3BV6A 2WYMA 4AD9A 1X8HA 5AHRA 4HL2A 3F9OA 2P18A 4RBSA 3AJ3A 4WD6A 5EHTA 4P62A 4GYQA 5LSCA 3IE1A 3ZNBA 2GMNA 2GCUA 3BK2A 2BC2A 5LMCA 1HLKA 3I0VA 1WW1A 2BG2A 2YNUA 5EVBA 1QH5A 1A7TA 2YZ3A 5LS3A 3SPUA 3QH8A 1BMCA 1SMLA 1JT1A 2BFZA 4RAMA 2NXAA 3X2YA 3VQZA 1VJNA 5AXOA 5DPXA 1YCGA 1BVTA 1X8IA 4KEPA 2HB9A 2GKLA 2M5DA 3X2ZA 3G1PA 2WYMC 5ACRA 1JJTA 5EV8A 3Q6VA 5IQKA 2FU9A 2ZNBA 1WUPA 2Q9UA 4U4LA 4TZ9A 2R2DA 3ESHA 2BR6A 5K4MA 3T9MA 5A5ZA 4UAMA 3SRXA 5AHOA 5ACQA 3WXCA 1DXKA 3IDZA 5ACTA 4D02A 1ZNBA 4V0HA 5HH6A 4D1TA 4UWSB 4F6ZA 3IOFA 2A7MA 2DOOA 5ACVA 2QEDA 4Z5YA 5AEBA 2E7YA 3DHCA 5A87A 4UWPB 4EY2A 4TZEA 3AF6A 5EVKA 4PVTA 4EFZA 4HL1A 2BG8B 4NQ5A 2OHIA 2FHXB 2P1EA 4LE6A 2Q42A 2AIOA 2BIBA 1MQOA 5HH4A 3IEKA 5K4NA 4H0DA 3R2UA 3JXPA 2NYPA 1M2XA 2Y87A 3DHAA 5LE1A 4C1CA 4NQ2A 4O98A 3RKKA 2QDTA 1VMEA 3ZR9A 4RAWA 4C1GA 1DD6A 2ZZIA 3SD9A 4C09A 1KO2A 2H6AA 5A0VA 4C1EA 2M5CA 4XUKA 1ZTCA 4GYUA 2CBNA 5HH5A 1VGNA 2FU7A 2UYXA 3IEMA 4BZ3A 4Z7RA 3I14A 3ZWFA 4AX1B 1YCFA 4NQ6A 2VW8A 1K07A 4D1UA 2ZWRA 3FAIA 4GCWA 2BTNA 3H3EA 3I15A 2AZ4A 1JJEA 4DIKA 4TZFA 2NZEA 3BK1A 3IOGA 2WHGA 4RM5A 5EV6A 4UWRB 1Y44A 1ZKPA 5AYAA 5HIOA 3KL7A 3IE0A 3DHBA 4Z6XA 2Y8BA 2XR1A 2YNWA 4FSBA 4KEQA 5HIQA 4TYTA 4TYFA 5ACPA 2YCBA 4AX0B 1WUOA 2BFLA 3S0ZA 4ZNBA 5A0TA 2OHJA 3SW3A 3FCZA 4EYLA 4FR7A 1P9EA 3A4YA 4C1FA 3X30A 5KILA 2QINA 4Z60A 5LCHA 5ACUA 3X2XA 4CHLA 2BFKA 4J5FA 4UWOB 5HIPA 2Y8AA 2Q0IA 5K0WA 4PVOA 4J5HA 5EVDA 2Q0JA 4FEKA 2YNVB 4Z5ZA 1KO3A 2BG7A 1DDKA 5ACXA 3AF5A 4B87A 4D1VA 5KIKA 2ZO4A 2YNTB 3PY5A 3P2UA 4AWZA 2I7XA 4EXYA 2DKFA 3DH8A 1WRAA 3SBLA 4C1DA 4DILA 2P4ZA 2QJSA 3BC2A 3I13A 2BG6A 4RL0A 5LLDA 5B15A 2QDSA 2BMIA 3IELA 3RKJA 3LVZA 4XWTA 2NZFA 4XWWA 3VPEA 1XM8A 5FQBA 4EYBA 3IE2A 3T3OA 3L6NA 4Z67A 4ZO2A 3SFPA 2FU8A 2XF4A 4RL2A 2FM6A 1L9YA 1E5DA 3ZQ4A 3KNRA 1XTOA 4YSBA 4TZBA 3RPCA 3KNSA 5HISA 3PY6A 2BG8A 4F6HA 2BGAA 3I11A 2FHXA 4BP0A 2OHHA 5FQCA 5B1UA 4EXSA 1BC2A 2P97A 4YSKA 4YSLA 4D1WA 4ZEJA 2YNVA 2I7VA 1YCHA 2BFZB 2YNTA 1A8TA 5FQAA 3TP9A 2WRSA 5EW0A 4C1HA 1KR3A 4EYFA 2GFKA 5K4KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5EWA A;  4NQ4 A;  2FU6 A;  3PG4 A;  2GFJ A;  3MD7 A;  5LCA A;  5AXR A;  1X8G A;  3T3N A;  4UBQ A;  1QH3 A;  3ADR A;  4HKY A;  4JO0 A;  2I7T A;  4AWY B;  5LCF A;  2WYL A;  2FK6 A;  5EH9 A;  5B3R A;  5ACS A;  5LM6 A;  4UA4 A;  4ZO3 A;  5ACW A;  3BV6 A;  2WYM A;  4AD9 A;  1X8H A;  5AHR A;  4HL2 A;  3F9O A;  2P18 A;  4RBS A;  3AJ3 A;  4WD6 A;  5EHT A;  4P62 A;  4GYQ A;  5LSC A;  3IE1 A;  3ZNB A;  2GMN A;  2GCU A;  3BK2 A;  2BC2 A;  5LMC A;  1HLK A;  3I0V A;  1WW1 A;  2BG2 A;  2YNU A;  5EVB A;  1QH5 A;  1A7T A;  2YZ3 A;  5LS3 A;  3SPU A;  3QH8 A;  1BMC A;  1SML A;  1JT1 A;  2BFZ A;  4RAM A;  2NXA A;  3X2Y A;  3VQZ A;  1VJN A;  5AXO A;  5DPX A;  1YCG A;  1BVT A;  1X8I A;  4KEP A;  2HB9 A;  2GKL A;  2M5D A;  3X2Z A;  3G1P A;  2WYM C;  5ACR A;  1JJT A;  5EV8 A;  3Q6V A;  5IQK A;  2FU9 A;  2ZNB A;  1WUP A;  2Q9U A;  4U4L A;  4TZ9 A;  2R2D A;  3ESH A;  2BR6 A;  5K4M A;  3T9M A;  5A5Z A;  4UAM A;  3SRX A;  5AHO A;  5ACQ A;  3WXC A;  1DXK A;  3IDZ A;  5ACT A;  4D02 A;  1ZNB A;  4V0H A;  5HH6 A;  4D1T A;  4UWS B;  4F6Z A;  3IOF A;  2A7M A;  2DOO A;  5ACV A;  2QED A;  4Z5Y A;  5AEB A;  2E7Y A;  3DHC A;  5A87 A;  4UWP B;  4EY2 A;  4TZE A;  3AF6 A;  5EVK A;  4PVT A;  4EFZ A;  4HL1 A;  2BG8 B;  4NQ5 A;  2OHI A;  2FHX B;  2P1E A;  4LE6 A;  2Q42 A;  2AIO A;  2BIB A;  1MQO A;  5HH4 A;  3IEK A;  5K4N A;  4H0D A;  3R2U A;  3JXP A;  2NYP A;  1M2X A;  2Y87 A;  3DHA A;  5LE1 A;  4C1C A;  4NQ2 A;  4O98 A;  3RKK A;  2QDT A;  1VME A;  3ZR9 A;  4RAW A;  4C1G A;  1DD6 A;  2ZZI A;  3SD9 A;  4C09 A;  1KO2 A;  2H6A A;  5A0V A;  4C1E A;  2M5C A;  4XUK A;  1ZTC A;  4GYU A;  2CBN A;  5HH5 A;  1VGN A;  2FU7 A;  2UYX A;  3IEM A;  4BZ3 A;  4Z7R A;  3I14 A;  3ZWF A;  4AX1 B;  1YCF A;  4NQ6 A;  2VW8 A;  1K07 A;  4D1U A;  2ZWR A;  3FAI A;  4GCW A;  2BTN A;  3H3E A;  3I15 A;  2AZ4 A;  1JJE A;  4DIK A;  4TZF A;  2NZE A;  3BK1 A;  3IOG A;  2WHG A;  4RM5 A;  5EV6 A;  4UWR B;  1Y44 A;  1ZKP A;  5AYA A;  5HIO A;  3KL7 A;  3IE0 A;  3DHB A;  4Z6X A;  2Y8B A;  2XR1 A;  2YNW A;  4FSB A;  4KEQ A;  5HIQ A;  4TYT A;  4TYF A;  5ACP A;  2YCB A;  4AX0 B;  1WUO A;  2BFL A;  3S0Z A;  4ZNB A;  5A0T A;  2OHJ A;  3SW3 A;  3FCZ A;  4EYL A;  4FR7 A;  1P9E A;  3A4Y A;  4C1F A;  3X30 A;  5KIL A;  2QIN A;  4Z60 A;  5LCH A;  5ACU A;  3X2X A;  4CHL A;  2BFK A;  4J5F A;  4UWO B;  5HIP A;  2Y8A A;  2Q0I A;  5K0W A;  4PVO A;  4J5H A;  5EVD A;  2Q0J A;  4FEK A;  2YNV B;  4Z5Z A;  1KO3 A;  2BG7 A;  1DDK A;  5ACX A;  3AF5 A;  4B87 A;  4D1V A;  5KIK A;  2ZO4 A;  2YNT B;  3PY5 A;  3P2U A;  4AWZ A;  2I7X A;  4EXY A;  2DKF A;  3DH8 A;  1WRA A;  3SBL A;  4C1D A;  4DIL A;  2P4Z A;  2QJS A;  3BC2 A;  3I13 A;  2BG6 A;  4RL0 A;  5LLD A;  5B15 A;  2QDS A;  2BMI A;  3IEL A;  3RKJ A;  3LVZ A;  4XWT A;  2NZF A;  4XWW A;  3VPE A;  1XM8 A;  5FQB A;  4EYB A;  3IE2 A;  3T3O A;  3L6N A;  4Z67 A;  4ZO2 A;  3SFP A;  2FU8 A;  2XF4 A;  4RL2 A;  2FM6 A;  1L9Y A;  1E5D A;  3ZQ4 A;  3KNR A;  1XTO A;  4YSB A;  4TZB A;  3RPC A;  3KNS A;  5HIS A;  3PY6 A;  2BG8 A;  4F6H A;  2BGA A;  3I11 A;  2FHX A;  4BP0 A;  2OHH A;  5FQC A;  5B1U A;  4EXS A;  1BC2 A;  2P97 A;  4YSK A;  4YSL A;  4D1W A;  4ZEJ A;  2YNV A;  2I7V A;  1YCH A;  2BFZ B;  2YNT A;  1A8T A;  5FQA A;  3TP9 A;  2WRS A;  5EW0 A;  4C1H A;  1KR3 A;  4EYF A;  2GFK A;  5K4K A; 
#chains in the Genus database with same CATH topology
 5EWA A;  4NQ4 A;  2FU6 A;  3PG4 A;  2GFJ A;  3MD7 A;  5LCA A;  5AXR A;  1X8G A;  3T3N A;  4UBQ A;  1QH3 A;  3ADR A;  4HKY A;  4JO0 A;  2I7T A;  4AWY B;  5LCF A;  2WYL A;  2FK6 A;  5EH9 A;  5B3R A;  5ACS A;  5LM6 A;  4UA4 A;  4ZO3 A;  5ACW A;  3BV6 A;  2WYM A;  4AD9 A;  1X8H A;  5AHR A;  4HL2 A;  3F9O A;  2P18 A;  4RBS A;  3AJ3 A;  4WD6 A;  5EHT A;  4P62 A;  4GYQ A;  5LSC A;  3IE1 A;  3ZNB A;  2GMN A;  2GCU A;  3BK2 A;  2BC2 A;  5LMC A;  1HLK A;  3I0V A;  1WW1 A;  2BG2 A;  2YNU A;  5EVB A;  1QH5 A;  1A7T A;  2YZ3 A;  5LS3 A;  3SPU A;  3QH8 A;  1BMC A;  1SML A;  1JT1 A;  2BFZ A;  4RAM A;  2NXA A;  2YHE A;  3X2Y A;  3VQZ A;  1VJN A;  5AXO A;  5DPX A;  1YCG A;  1BVT A;  1X8I A;  4KEP A;  2HB9 A;  2GKL A;  2M5D A;  3X2Z A;  3G1P A;  2WYM C;  5ACR A;  1JJT A;  5EV8 A;  3Q6V A;  5IQK A;  2FU9 A;  2CFZ A;  2ZNB A;  1WUP A;  2Q9U A;  4U4L A;  4TZ9 A;  2R2D A;  3ESH A;  2BR6 A;  5K4M A;  3T9M A;  5A5Z A;  4UAM A;  3SRX A;  5AHO A;  5ACQ A;  3WXC A;  1DXK A;  3IDZ A;  5ACT A;  4D02 A;  1ZNB A;  4V0H A;  5HH6 A;  4D1T A;  4UWS B;  4F6Z A;  3IOF A;  2A7M A;  2DOO A;  5ACV A;  2QED A;  4Z5Y A;  5AEB A;  2E7Y A;  3DHC A;  5A87 A;  4UWP B;  4EY2 A;  4TZE A;  3AF6 A;  5EVK A;  4PVT A;  4EFZ A;  4HL1 A;  2BG8 B;  4NQ5 A;  2OHI A;  2FHX B;  2P1E A;  4LE6 A;  2Q42 A;  2AIO A;  2BIB A;  1MQO A;  5HH4 A;  3IEK A;  5K4N A;  4H0D A;  3R2U A;  3JXP A;  2NYP A;  4PDX A;  1M2X A;  2Y87 A;  3DHA A;  5LE1 A;  4C1C A;  4NQ2 A;  4O98 A;  3RKK A;  2QDT A;  4AXH A;  1VME A;  3ZR9 A;  4RAW A;  4C1G A;  1DD6 A;  2ZZI A;  3SD9 A;  4C09 A;  1KO2 A;  2H6A A;  5A0V A;  4C1E A;  2M5C A;  4XUK A;  1ZTC A;  4GYU A;  2CBN A;  5HH5 A;  1VGN A;  2FU7 A;  2UYX A;  3IEM A;  4BZ3 A;  4Z7R A;  3I14 A;  3ZWF A;  4AX1 B;  1YCF A;  4NQ6 A;  2VW8 A;  1K07 A;  4D1U A;  2ZWR A;  2CFU A;  3FAI A;  4GCW A;  2BTN A;  3H3E A;  3I15 A;  2AZ4 A;  1JJE A;  4DIK A;  4TZF A;  2NZE A;  3BK1 A;  3IOG A;  2WHG A;  4RM5 A;  5EV6 A;  4UWR B;  1Y44 A;  5AJL A;  1ZKP A;  5AYA A;  5HIO A;  3KL7 A;  3IE0 A;  3DHB A;  4Z6X A;  2Y8B A;  2XR1 A;  2YNW A;  4FSB A;  4KEQ A;  5HIQ A;  4TYT A;  4TYF A;  5ACP A;  2YCB A;  4AX0 B;  1WUO A;  2BFL A;  2CG2 A;  3S0Z A;  4ZNB A;  5A0T A;  2OHJ A;  3SW3 A;  3FCZ A;  4EYL A;  4FR7 A;  1P9E A;  3A4Y A;  4C1F A;  3X30 A;  5KIL A;  2QIN A;  4Z60 A;  5LCH A;  5ACU A;  3X2X A;  4CHL A;  2BFK A;  4J5F A;  4UWO B;  5HIP A;  2Y8A A;  2Q0I A;  5K0W A;  4PVO A;  4J5H A;  5EVD A;  2Q0J A;  4FEK A;  2YNV B;  4Z5Z A;  1KO3 A;  2BG7 A;  1DDK A;  5ACX A;  3AF5 A;  4B87 A;  4D1V A;  5KIK A;  2ZO4 A;  2YNT B;  3PY5 A;  3P2U A;  4AWZ A;  2I7X A;  2DKF A;  3DH8 A;  4AV7 A;  1WRA A;  4EXY A;  3SBL A;  4C1D A;  4DIL A;  2P4Z A;  2QJS A;  3BC2 A;  3I13 A;  2BG6 A;  4NUR A;  4RL0 A;  5LLD A;  5B15 A;  2QDS A;  2BMI A;  3IEL A;  3RKJ A;  3LVZ A;  4XWT A;  2NZF A;  4XWW A;  3VPE A;  1XM8 A;  5FQB A;  4EYB A;  3IE2 A;  3T3O A;  3L6N A;  4Z67 A;  4ZO2 A;  3SFP A;  2FU8 A;  2XF4 A;  4RL2 A;  2FM6 A;  1L9Y A;  5AIJ A;  1E5D A;  3ZQ4 A;  3KNR A;  1XTO A;  4YSB A;  4TZB A;  3RPC A;  3KNS A;  5HIS A;  3PY6 A;  2BG8 A;  4F6H A;  2BGA A;  3I11 A;  2FHX A;  5A23 A;  4BP0 A;  2OHH A;  5FQC A;  5B1U A;  4EXS A;  2CG3 A;  1BC2 A;  2P97 A;  4YSK A;  4YSL A;  4D1W A;  4ZEJ A;  2YNV A;  2I7V A;  1YCH A;  2BFZ B;  2YNT A;  1A8T A;  5FQA A;  3TP9 A;  2WRS A;  5EW0 A;  4C1H A;  1KR3 A;  4EYF A;  2GFK A;  5K4K A; 
#chains in the Genus database with same CATH homology
 5EWA A;  4NQ4 A;  2FU6 A;  3PG4 A;  2GFJ A;  3MD7 A;  5LCA A;  5AXR A;  1X8G A;  3T3N A;  4UBQ A;  1QH3 A;  3ADR A;  4HKY A;  4JO0 A;  2I7T A;  4AWY B;  5LCF A;  2WYL A;  2FK6 A;  5EH9 A;  5B3R A;  5ACS A;  5LM6 A;  4UA4 A;  4ZO3 A;  5ACW A;  3BV6 A;  2WYM A;  4AD9 A;  1X8H A;  5AHR A;  4HL2 A;  3F9O A;  2P18 A;  4RBS A;  3AJ3 A;  4WD6 A;  5EHT A;  4P62 A;  4GYQ A;  5LSC A;  3IE1 A;  3ZNB A;  2GMN A;  2GCU A;  3BK2 A;  2BC2 A;  5LMC A;  1HLK A;  3I0V A;  1WW1 A;  2BG2 A;  2YNU A;  5EVB A;  1QH5 A;  1A7T A;  2YZ3 A;  5LS3 A;  3SPU A;  3QH8 A;  1BMC A;  1SML A;  1JT1 A;  2BFZ A;  4RAM A;  2NXA A;  3X2Y A;  3VQZ A;  1VJN A;  5AXO A;  5DPX A;  1YCG A;  1BVT A;  1X8I A;  4KEP A;  2HB9 A;  2GKL A;  2M5D A;  3X2Z A;  3G1P A;  2WYM C;  5ACR A;  1JJT A;  5EV8 A;  3Q6V A;  5IQK A;  2FU9 A;  2ZNB A;  1WUP A;  2Q9U A;  4U4L A;  4TZ9 A;  2R2D A;  3ESH A;  2BR6 A;  5K4M A;  3T9M A;  5A5Z A;  4UAM A;  3SRX A;  5AHO A;  5ACQ A;  3WXC A;  1DXK A;  3IDZ A;  5ACT A;  4D02 A;  1ZNB A;  4V0H A;  5HH6 A;  4D1T A;  4UWS B;  4F6Z A;  3IOF A;  2A7M A;  2DOO A;  5ACV A;  2QED A;  4Z5Y A;  5AEB A;  2E7Y A;  3DHC A;  5A87 A;  4UWP B;  4EY2 A;  4TZE A;  3AF6 A;  5EVK A;  4PVT A;  4EFZ A;  4HL1 A;  2BG8 B;  4NQ5 A;  2OHI A;  2FHX B;  2P1E A;  4LE6 A;  2Q42 A;  2AIO A;  2BIB A;  1MQO A;  5HH4 A;  3IEK A;  5K4N A;  4H0D A;  3R2U A;  3JXP A;  2NYP A;  1M2X A;  2Y87 A;  3DHA A;  5LE1 A;  4C1C A;  4NQ2 A;  4O98 A;  3RKK A;  2QDT A;  1VME A;  3ZR9 A;  4RAW A;  4C1G A;  1DD6 A;  2ZZI A;  3SD9 A;  4C09 A;  1KO2 A;  2H6A A;  5A0V A;  4C1E A;  2M5C A;  4XUK A;  1ZTC A;  4GYU A;  2CBN A;  5HH5 A;  1VGN A;  2FU7 A;  2UYX A;  3IEM A;  4BZ3 A;  4Z7R A;  3I14 A;  3ZWF A;  4AX1 B;  1YCF A;  4NQ6 A;  2VW8 A;  1K07 A;  4D1U A;  2ZWR A;  3FAI A;  4GCW A;  2BTN A;  3H3E A;  3I15 A;  2AZ4 A;  1JJE A;  4DIK A;  4TZF A;  2NZE A;  3BK1 A;  3IOG A;  2WHG A;  4RM5 A;  5EV6 A;  4UWR B;  1Y44 A;  1ZKP A;  5AYA A;  5HIO A;  3KL7 A;  3IE0 A;  3DHB A;  4Z6X A;  2Y8B A;  2XR1 A;  2YNW A;  4FSB A;  4KEQ A;  5HIQ A;  4TYT A;  4TYF A;  5ACP A;  2YCB A;  4AX0 B;  1WUO A;  2BFL A;  3S0Z A;  4ZNB A;  5A0T A;  2OHJ A;  3SW3 A;  3FCZ A;  4EYL A;  4FR7 A;  1P9E A;  3A4Y A;  4C1F A;  3X30 A;  5KIL A;  2QIN A;  4Z60 A;  5LCH A;  5ACU A;  3X2X A;  4CHL A;  2BFK A;  4J5F A;  4UWO B;  5HIP A;  2Y8A A;  2Q0I A;  5K0W A;  4PVO A;  4J5H A;  5EVD A;  2Q0J A;  4FEK A;  2YNV B;  4Z5Z A;  1KO3 A;  2BG7 A;  1DDK A;  5ACX A;  3AF5 A;  4B87 A;  4D1V A;  5KIK A;  2ZO4 A;  2YNT B;  3PY5 A;  3P2U A;  4AWZ A;  2I7X A;  4EXY A;  2DKF A;  3DH8 A;  1WRA A;  3SBL A;  4C1D A;  4DIL A;  2P4Z A;  2QJS A;  3BC2 A;  3I13 A;  2BG6 A;  4RL0 A;  5LLD A;  5B15 A;  2QDS A;  2BMI A;  3IEL A;  3RKJ A;  3LVZ A;  4XWT A;  2NZF A;  4XWW A;  3VPE A;  1XM8 A;  5FQB A;  4EYB A;  3IE2 A;  3T3O A;  3L6N A;  4Z67 A;  4ZO2 A;  3SFP A;  2FU8 A;  2XF4 A;  4RL2 A;  2FM6 A;  1L9Y A;  1E5D A;  3ZQ4 A;  3KNR A;  1XTO A;  4YSB A;  4TZB A;  3RPC A;  3KNS A;  5HIS A;  3PY6 A;  2BG8 A;  4F6H A;  2BGA A;  3I11 A;  2FHX A;  4BP0 A;  2OHH A;  5FQC A;  5B1U A;  4EXS A;  1BC2 A;  2P97 A;  4YSK A;  4YSL A;  4D1W A;  4ZEJ A;  2YNV A;  2I7V A;  1YCH A;  2BFZ B;  2YNT A;  1A8T A;  5FQA A;  3TP9 A;  2WRS A;  5EW0 A;  4C1H A;  1KR3 A;  4EYF A;  2GFK A;  5K4K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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