3FCZA

Adaptive protein evolution grants organismal fitness by improving catalysis and flexibility
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
222
structure length
219
Chain Sequence
KTVIKNETGTISISQLNKNVWVHTELGSFAVPSSGLVLNTSKGLVLVDSSWDDKLTKELIEMVEKKFQKRVTDAIITHAHADRIGGIKTLKERGIKAHSTALTAELAKKNGYEEPLGDLQTVTNLKFGNMKVETFYPGKGHTEDNIVVWLPQYNILVGGCLVKSTSAKDLGNVADAYVNEWSTSIENVSKRYRNINAVVPSHGEVGDKGLLLHTLDLLK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Beta-lactamase 2
publication title Adaptive protein evolution grants organismal fitness by improving catalysis and flexibility.
pubmed doi rcsb
source organism Bacillus cereus
molecule tags Hydrolase
total genus 69
structure length 219
sequence length 222
chains with identical sequence B
ec nomenclature ec 3.5.2.6: Beta-lactamase.
pdb deposition date 2008-11-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 3fczA00
2I7XA 2YNWA 5LCHA 5A87A 2NYPA 3IE0A 2OHIA 1X8IA 4EYBA 2Q9UA 2E7YA 2M5DA 1A8TA 2WRSA 5AXRA 2DOOA 1X8GA 5LSCA 2FHXA 5A5ZA 2FU6A 4GYQA 2DKFA 4ZO2A 2Q0JA 4AWZA 3IDZA 3TP9A 3SW3A 5AEBA 3I11A 2A7MA 2BFZB 2BC2A 4HL2A 5ACTA 2P1EA 5ACWA 4EY2A 3IE2A 3SD9A 4RM5A 1XTOA 4BZ3A 2Q0IA 2Y8AA 4NQ5A 5AHRA 4UBQA 1HLKA 2ZZIA 2HB9A 2I7TA 3SFPA 5ACPA 5LE1A 4RL2A 5ACXA 3G1PA 5EH9A 3X2YA 4F6ZA 5HIOA 4RAWA 1BMCA 1XM8A 4UWOB 4HKYA 5AHOA 3LVZA 5ACQA 2ZNBA 4Z6XA 5HH5A 2GCUA 2FHXB 2YNUA 4F6HA 3I13A 5LLDA 2YCBA 5ACUA 3IE1A 2GFJA 3SBLA 2M5CA 2FK6A 4NQ6A 4CHLA 5EV6A 3H3EA 4J5HA 2YZ3A 3ZQ4A 4Z67A 4Z7RA 5KIKA 2BG2A 3KNSA 5KILA 5A0TA 3FAIA 3IEMA 5ACSA 2H6AA 5B1UA 2FU9A 3T3NA 2NXAA 4C1CA 5ACVA 5HH6A 1KO2A 1M2XA 4AX0B 4C1EA 5HH4A 3AF6A 1YCFA 1WRAA 3A4YA 5A0VA 2YNVB 2BG8A 1SMLA 4TYTA 4WD6A 4EFZA 4DIKA 3S0ZA 1ZTCA 2XR1A 4AD9A 3DH8A 1KO3A 1DDKA 1L9YA 3P2UA 3RKJA 2NZEA 4Z5ZA 4FEKA 3BK2A 3R2UA 2WYMC 2QJSA 2BR6A 4D1VA 4J5FA 5LCAA 3F9OA 2QINA 4C1DA 4UA4A 4JO0A 4LE6A 3SRXA 2QDTA 2YNTA 3ZR9A 4XWTA 2GFKA 5LS3A 2QEDA 2AIOA 5B15A 5B3RA 5AYAA 2BG7A 1X8HA 2QDSA 4FSBA 4NQ2A 4ZNBA 4H0DA 5LMCA 2OHHA 1MQOA 4YSBA 4UAMA 5FQCA 1QH5A 4BP0A 2Y8BA 4D1TA 4ZEJA 2BG6A 4B87A 4EYFA 1DD6A 3RPCA 3AJ3A 2GKLA 1BC2A 1JJEA 3Q6VA 2P97A 4GYUA 4P62A 5EHTA 5K0WA 1KR3A 4NQ4A 4TZBA 2BGAA 3IELA 1E5DA 2I7VA 5HIQA 2WHGA 2WYMA 5IQKA 5EVBA 1WW1A 3DHAA 3ZNBA 2BTNA 4XUKA 4EXSA 3KL7A 3X2ZA 3VPEA 2ZWRA 3BV6A 5K4NA 4TYFA 4C1GA 5DPXA 4YSKA 3X30A 3DHBA 5K4MA 4C09A 3IOFA 2UYXA 2BFKA 4Z60A 4UWPB 2WYLA 3ESHA 4KEPA 3L6NA 5EWAA 3I15A 1VJNA 4FR7A 1A7TA 2BMIA 4ZO3A 2GMNA 4EXYA 3QH8A 5K4KA 4KEQA 3BC2A 4C1HA 4D02A 4RAMA 3RKKA 4D1UA 1JT1A 4PVOA 1JJTA 4RBSA 1YCHA 1VGNA 4D1WA 2OHJA 4UWRB 4V0HA 1P9EA 3DHCA 3IOGA 4HL1A 2Q42A 3T3OA 3JXPA 5EV8A 5EVDA 4UWSB 3ZWFA 5LCFA 1WUPA 3ADRA 3FCZA 5HIPA 5EW0A 3I14A 1VMEA 4TZ9A 2FM6A 4AX1B 5FQAA 4TZEA 5ACRA 3PG4A 3BK1A 2Y87A 1K07A 4AWYB 4XWWA 4U4LA 4YSLA 3PY5A 4PVTA 3SPUA 3X2XA 2AZ4A 2BG8B 2FU8A 1ZKPA 1QH3A 2BFLA 2P18A 4C1FA 2ZO4A 1YCGA 2FU7A 1BVTA 4Z5YA 2XF4A 2YNVA 2BIBA 1ZNBA 3KNRA 3T9MA 4O98A 2P4ZA 1Y44A 2YNTB 1DXKA 2BFZA 3WXCA 4RL0A 4GCWA 4DILA 2R2DA 5EVKA 3IEKA 3PY6A 5HISA 3VQZA 1WUOA 4TZFA 3I0VA 5LM6A 5FQBA 3AF5A 4EYLA 5AXOA 2CBNA 2VW8A 2NZFA 3MD7A
chains in the Genus database with same CATH superfamily
2I7XA 2YNWA 5LCHA 5A87A 2NYPA 3IE0A 2OHIA 1X8IA 4EYBA 2Q9UA 2E7YA 2M5DA 1A8TA 2WRSA 5AXRA 2DOOA 1X8GA 5LSCA 2FHXA 5A5ZA 2FU6A 4GYQA 2DKFA 5A23A 4NURA 4ZO2A 2Q0JA 4AWZA 3IDZA 3TP9A 3SW3A 5AEBA 3I11A 2A7MA 2BFZB 2BC2A 2YHEA 4HL2A 5ACTA 2P1EA 5ACWA 4EY2A 3IE2A 2CFUA 3SD9A 4RM5A 1XTOA 4BZ3A 2Q0IA 2Y8AA 4NQ5A 5AHRA 4UBQA 1HLKA 2ZZIA 2HB9A 2I7TA 3SFPA 5ACPA 5LE1A 4RL2A 5ACXA 3G1PA 5EH9A 3X2YA 4F6ZA 5HIOA 4RAWA 1BMCA 1XM8A 4UWOB 4HKYA 5AHOA 3LVZA 5ACQA 2ZNBA 5AIJA 4Z6XA 5HH5A 2GCUA 2FHXB 2YNUA 4F6HA 3I13A 5LLDA 2YCBA 5ACUA 3IE1A 2GFJA 3SBLA 2M5CA 2FK6A 4NQ6A 4CHLA 5EV6A 3H3EA 4J5HA 2YZ3A 3ZQ4A 4Z67A 4Z7RA 5KIKA 2BG2A 3KNSA 5KILA 5A0TA 3FAIA 3IEMA 5ACSA 2H6AA 5B1UA 2FU9A 3T3NA 2NXAA 4C1CA 5ACVA 5HH6A 1KO2A 1M2XA 4AX0B 4C1EA 5HH4A 3AF6A 1YCFA 1WRAA 3A4YA 5A0VA 2YNVB 2BG8A 1SMLA 4TYTA 4WD6A 4EFZA 4DIKA 3S0ZA 1ZTCA 2XR1A 4AD9A 3DH8A 1KO3A 1DDKA 1L9YA 3P2UA 3RKJA 2NZEA 4Z5ZA 4FEKA 3BK2A 3R2UA 2WYMC 2QJSA 2BR6A 4D1VA 4J5FA 5LCAA 3F9OA 2QINA 4C1DA 4UA4A 4JO0A 4LE6A 3SRXA 2QDTA 2YNTA 3ZR9A 4XWTA 2GFKA 5LS3A 2QEDA 4AV7A 2AIOA 5B15A 5B3RA 5AYAA 2BG7A 1X8HA 2QDSA 4FSBA 4NQ2A 4ZNBA 4H0DA 5LMCA 2OHHA 1MQOA 4YSBA 4UAMA 5FQCA 1QH5A 4BP0A 2Y8BA 4D1TA 4ZEJA 2BG6A 4B87A 4EYFA 1DD6A 3RPCA 3AJ3A 2GKLA 1BC2A 1JJEA 3Q6VA 2P97A 4GYUA 4P62A 5EHTA 5K0WA 4PDXA 1KR3A 4NQ4A 4TZBA 2BGAA 3IELA 1E5DA 2I7VA 5HIQA 2WHGA 2WYMA 5IQKA 5EVBA 1WW1A 3DHAA 3ZNBA 2BTNA 4XUKA 4EXSA 3KL7A 3X2ZA 3VPEA 2ZWRA 3BV6A 5K4NA 4AXHA 4TYFA 4C1GA 5DPXA 4YSKA 3X30A 3DHBA 5K4MA 4C09A 3IOFA 2UYXA 2BFKA 4Z60A 4UWPB 2WYLA 3ESHA 4KEPA 3L6NA 5EWAA 3I15A 1VJNA 4FR7A 1A7TA 2BMIA 4ZO3A 2GMNA 4EXYA 3QH8A 5K4KA 4KEQA 3BC2A 4C1HA 4D02A 4RAMA 3RKKA 4D1UA 1JT1A 4PVOA 1JJTA 4RBSA 1YCHA 1VGNA 4D1WA 2OHJA 4UWRB 4V0HA 1P9EA 3DHCA 3IOGA 4HL1A 2Q42A 3T3OA 3JXPA 5EV8A 2CG3A 5EVDA 4UWSB 3ZWFA 5LCFA 1WUPA 3ADRA 3FCZA 5HIPA 5EW0A 3I14A 1VMEA 4TZ9A 2FM6A 4AX1B 5FQAA 4TZEA 5ACRA 3PG4A 3BK1A 2Y87A 1K07A 4AWYB 4XWWA 4U4LA 4YSLA 3PY5A 4PVTA 3SPUA 3X2XA 2AZ4A 2BG8B 2CG2A 2FU8A 1ZKPA 1QH3A 2BFLA 2P18A 4C1FA 2ZO4A 1YCGA 2FU7A 1BVTA 4Z5YA 2XF4A 2YNVA 2BIBA 1ZNBA 3KNRA 3T9MA 4O98A 2P4ZA 1Y44A 2YNTB 5AJLA 1DXKA 2BFZA 3WXCA 4RL0A 2CFZA 4GCWA 4DILA 2R2DA 5EVKA 3IEKA 3PY6A 5HISA 3VQZA 1WUOA 4TZFA 3I0VA 5LM6A 5FQBA 3AF5A 4EYLA 5AXOA 2CBNA 2VW8A 2NZFA 3MD7A
chains in the Genus database with same CATH topology
2I7XA 2YNWA 5LCHA 5A87A 2NYPA 3IE0A 2OHIA 1X8IA 4EYBA 2Q9UA 2E7YA 2M5DA 1A8TA 2WRSA 5AXRA 2DOOA 1X8GA 5LSCA 2FHXA 5A5ZA 2FU6A 4GYQA 2DKFA 4ZO2A 2Q0JA 4AWZA 3IDZA 3TP9A 3SW3A 5AEBA 3I11A 2A7MA 2BFZB 2BC2A 4HL2A 5ACTA 2P1EA 5ACWA 4EY2A 3IE2A 3SD9A 4RM5A 1XTOA 4BZ3A 2Q0IA 2Y8AA 4NQ5A 5AHRA 4UBQA 1HLKA 2ZZIA 2HB9A 2I7TA 3SFPA 5ACPA 5LE1A 4RL2A 5ACXA 3G1PA 5EH9A 3X2YA 4F6ZA 5HIOA 4RAWA 1BMCA 1XM8A 4UWOB 4HKYA 5AHOA 3LVZA 5ACQA 2ZNBA 4Z6XA 5HH5A 2GCUA 2FHXB 2YNUA 4F6HA 3I13A 5LLDA 2YCBA 5ACUA 3IE1A 2GFJA 3SBLA 2M5CA 2FK6A 4NQ6A 4CHLA 5EV6A 3H3EA 4J5HA 2YZ3A 3ZQ4A 4Z67A 4Z7RA 5KIKA 2BG2A 3KNSA 5KILA 5A0TA 3FAIA 3IEMA 5ACSA 2H6AA 5B1UA 2FU9A 3T3NA 2NXAA 4C1CA 5ACVA 5HH6A 1KO2A 1M2XA 4AX0B 4C1EA 5HH4A 3AF6A 1YCFA 1WRAA 3A4YA 5A0VA 2YNVB 2BG8A 1SMLA 4TYTA 4WD6A 4EFZA 4DIKA 3S0ZA 1ZTCA 2XR1A 4AD9A 3DH8A 1KO3A 1DDKA 1L9YA 3P2UA 3RKJA 2NZEA 4Z5ZA 4FEKA 3BK2A 3R2UA 2WYMC 2QJSA 2BR6A 4D1VA 4J5FA 5LCAA 3F9OA 2QINA 4C1DA 4UA4A 4JO0A 4LE6A 3SRXA 2QDTA 2YNTA 3ZR9A 4XWTA 2GFKA 5LS3A 2QEDA 2AIOA 5B15A 5B3RA 5AYAA 2BG7A 1X8HA 2QDSA 4FSBA 4NQ2A 4ZNBA 4H0DA 5LMCA 2OHHA 1MQOA 4YSBA 4UAMA 5FQCA 1QH5A 4BP0A 2Y8BA 4D1TA 4ZEJA 2BG6A 4B87A 4EYFA 1DD6A 3RPCA 3AJ3A 2GKLA 1BC2A 1JJEA 3Q6VA 2P97A 4GYUA 4P62A 5EHTA 5K0WA 1KR3A 4NQ4A 4TZBA 2BGAA 3IELA 1E5DA 2I7VA 5HIQA 2WHGA 2WYMA 5IQKA 5EVBA 1WW1A 3DHAA 3ZNBA 2BTNA 4XUKA 4EXSA 3KL7A 3X2ZA 3VPEA 2ZWRA 3BV6A 5K4NA 4TYFA 4C1GA 5DPXA 4YSKA 3X30A 3DHBA 5K4MA 4C09A 3IOFA 2UYXA 2BFKA 4Z60A 4UWPB 2WYLA 3ESHA 4KEPA 3L6NA 5EWAA 3I15A 1VJNA 4FR7A 1A7TA 2BMIA 4ZO3A 2GMNA 4EXYA 3QH8A 5K4KA 4KEQA 3BC2A 4C1HA 4D02A 4RAMA 3RKKA 4D1UA 1JT1A 4PVOA 1JJTA 4RBSA 1YCHA 1VGNA 4D1WA 2OHJA 4UWRB 4V0HA 1P9EA 3DHCA 3IOGA 4HL1A 2Q42A 3T3OA 3JXPA 5EV8A 5EVDA 4UWSB 3ZWFA 5LCFA 1WUPA 3ADRA 3FCZA 5HIPA 5EW0A 3I14A 1VMEA 4TZ9A 2FM6A 4AX1B 5FQAA 4TZEA 5ACRA 3PG4A 3BK1A 2Y87A 1K07A 4AWYB 4XWWA 4U4LA 4YSLA 3PY5A 4PVTA 3SPUA 3X2XA 2AZ4A 2BG8B 2FU8A 1ZKPA 1QH3A 2BFLA 2P18A 4C1FA 2ZO4A 1YCGA 2FU7A 1BVTA 4Z5YA 2XF4A 2YNVA 2BIBA 1ZNBA 3KNRA 3T9MA 4O98A 2P4ZA 1Y44A 2YNTB 1DXKA 2BFZA 3WXCA 4RL0A 4GCWA 4DILA 2R2DA 5EVKA 3IEKA 3PY6A 5HISA 3VQZA 1WUOA 4TZFA 3I0VA 5LM6A 5FQBA 3AF5A 4EYLA 5AXOA 2CBNA 2VW8A 2NZFA 3MD7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2I7X A;  2YNW A;  5LCH A;  5A87 A;  2NYP A;  3IE0 A;  2OHI A;  1X8I A;  4EYB A;  2Q9U A;  2E7Y A;  2M5D A;  1A8T A;  2WRS A;  5AXR A;  2DOO A;  1X8G A;  5LSC A;  2FHX A;  5A5Z A;  2FU6 A;  4GYQ A;  2DKF A;  4ZO2 A;  2Q0J A;  4AWZ A;  3IDZ A;  3TP9 A;  3SW3 A;  5AEB A;  3I11 A;  2A7M A;  2BFZ B;  2BC2 A;  4HL2 A;  5ACT A;  2P1E A;  5ACW A;  4EY2 A;  3IE2 A;  3SD9 A;  4RM5 A;  1XTO A;  4BZ3 A;  2Q0I A;  2Y8A A;  4NQ5 A;  5AHR A;  4UBQ A;  1HLK A;  2ZZI A;  2HB9 A;  2I7T A;  3SFP A;  5ACP A;  5LE1 A;  4RL2 A;  5ACX A;  3G1P A;  5EH9 A;  3X2Y A;  4F6Z A;  5HIO A;  4RAW A;  1BMC A;  1XM8 A;  4UWO B;  4HKY A;  5AHO A;  3LVZ A;  5ACQ A;  2ZNB A;  4Z6X A;  5HH5 A;  2GCU A;  2FHX B;  2YNU A;  4F6H A;  3I13 A;  5LLD A;  2YCB A;  5ACU A;  3IE1 A;  2GFJ A;  3SBL A;  2M5C A;  2FK6 A;  4NQ6 A;  4CHL A;  5EV6 A;  3H3E A;  4J5H A;  2YZ3 A;  3ZQ4 A;  4Z67 A;  4Z7R A;  5KIK A;  2BG2 A;  3KNS A;  5KIL A;  5A0T A;  3FAI A;  3IEM A;  5ACS A;  2H6A A;  5B1U A;  2FU9 A;  3T3N A;  2NXA A;  4C1C A;  5ACV A;  5HH6 A;  1KO2 A;  1M2X A;  4AX0 B;  4C1E A;  5HH4 A;  3AF6 A;  1YCF A;  1WRA A;  3A4Y A;  5A0V A;  2YNV B;  2BG8 A;  1SML A;  4TYT A;  4WD6 A;  4EFZ A;  4DIK A;  3S0Z A;  1ZTC A;  2XR1 A;  4AD9 A;  3DH8 A;  1KO3 A;  1DDK A;  1L9Y A;  3P2U A;  3RKJ A;  2NZE A;  4Z5Z A;  4FEK A;  3BK2 A;  3R2U A;  2WYM C;  2QJS A;  2BR6 A;  4D1V A;  4J5F A;  5LCA A;  3F9O A;  2QIN A;  4C1D A;  4UA4 A;  4JO0 A;  4LE6 A;  3SRX A;  2QDT A;  2YNT A;  3ZR9 A;  4XWT A;  2GFK A;  5LS3 A;  2QED A;  2AIO A;  5B15 A;  5B3R A;  5AYA A;  2BG7 A;  1X8H A;  2QDS A;  4FSB A;  4NQ2 A;  4ZNB A;  4H0D A;  5LMC A;  2OHH A;  1MQO A;  4YSB A;  4UAM A;  5FQC A;  1QH5 A;  4BP0 A;  2Y8B A;  4D1T A;  4ZEJ A;  2BG6 A;  4B87 A;  4EYF A;  1DD6 A;  3RPC A;  3AJ3 A;  2GKL A;  1BC2 A;  1JJE A;  3Q6V A;  2P97 A;  4GYU A;  4P62 A;  5EHT A;  5K0W A;  1KR3 A;  4NQ4 A;  4TZB A;  2BGA A;  3IEL A;  1E5D A;  2I7V A;  5HIQ A;  2WHG A;  2WYM A;  5IQK A;  5EVB A;  1WW1 A;  3DHA A;  3ZNB A;  2BTN A;  4XUK A;  4EXS A;  3KL7 A;  3X2Z A;  3VPE A;  2ZWR A;  3BV6 A;  5K4N A;  4TYF A;  4C1G A;  5DPX A;  4YSK A;  3X30 A;  3DHB A;  5K4M A;  4C09 A;  3IOF A;  2UYX A;  2BFK A;  4Z60 A;  4UWP B;  2WYL A;  3ESH A;  4KEP A;  3L6N A;  5EWA A;  3I15 A;  1VJN A;  4FR7 A;  1A7T A;  2BMI A;  4ZO3 A;  2GMN A;  4EXY A;  3QH8 A;  5K4K A;  4KEQ A;  3BC2 A;  4C1H A;  4D02 A;  4RAM A;  3RKK A;  4D1U A;  1JT1 A;  4PVO A;  1JJT A;  4RBS A;  1YCH A;  1VGN A;  4D1W A;  2OHJ A;  4UWR B;  4V0H A;  1P9E A;  3DHC A;  3IOG A;  4HL1 A;  2Q42 A;  3T3O A;  3JXP A;  5EV8 A;  5EVD A;  4UWS B;  3ZWF A;  5LCF A;  1WUP A;  3ADR A;  3FCZ A;  5HIP A;  5EW0 A;  3I14 A;  1VME A;  4TZ9 A;  2FM6 A;  4AX1 B;  5FQA A;  4TZE A;  5ACR A;  3PG4 A;  3BK1 A;  2Y87 A;  1K07 A;  4AWY B;  4XWW A;  4U4L A;  4YSL A;  3PY5 A;  4PVT A;  3SPU A;  3X2X A;  2AZ4 A;  2BG8 B;  2FU8 A;  1ZKP A;  1QH3 A;  2BFL A;  2P18 A;  4C1F A;  2ZO4 A;  1YCG A;  2FU7 A;  1BVT A;  4Z5Y A;  2XF4 A;  2YNV A;  2BIB A;  1ZNB A;  3KNR A;  3T9M A;  4O98 A;  2P4Z A;  1Y44 A;  2YNT B;  1DXK A;  2BFZ A;  3WXC A;  4RL0 A;  4GCW A;  4DIL A;  2R2D A;  5EVK A;  3IEK A;  3PY6 A;  5HIS A;  3VQZ A;  1WUO A;  4TZF A;  3I0V A;  5LM6 A;  5FQB A;  3AF5 A;  4EYL A;  5AXO A;  2CBN A;  2VW8 A;  2NZF A;  3MD7 A; 
#chains in the Genus database with same CATH topology
 2I7X A;  2YNW A;  5LCH A;  5A87 A;  2NYP A;  3IE0 A;  2OHI A;  1X8I A;  4EYB A;  2Q9U A;  2E7Y A;  2M5D A;  1A8T A;  2WRS A;  5AXR A;  2DOO A;  1X8G A;  5LSC A;  2FHX A;  5A5Z A;  2FU6 A;  4GYQ A;  2DKF A;  5A23 A;  4NUR A;  4ZO2 A;  2Q0J A;  4AWZ A;  3IDZ A;  3TP9 A;  3SW3 A;  5AEB A;  3I11 A;  2A7M A;  2BFZ B;  2BC2 A;  2YHE A;  4HL2 A;  5ACT A;  2P1E A;  5ACW A;  4EY2 A;  3IE2 A;  2CFU A;  3SD9 A;  4RM5 A;  1XTO A;  4BZ3 A;  2Q0I A;  2Y8A A;  4NQ5 A;  5AHR A;  4UBQ A;  1HLK A;  2ZZI A;  2HB9 A;  2I7T A;  3SFP A;  5ACP A;  5LE1 A;  4RL2 A;  5ACX A;  3G1P A;  5EH9 A;  3X2Y A;  4F6Z A;  5HIO A;  4RAW A;  1BMC A;  1XM8 A;  4UWO B;  4HKY A;  5AHO A;  3LVZ A;  5ACQ A;  2ZNB A;  5AIJ A;  4Z6X A;  5HH5 A;  2GCU A;  2FHX B;  2YNU A;  4F6H A;  3I13 A;  5LLD A;  2YCB A;  5ACU A;  3IE1 A;  2GFJ A;  3SBL A;  2M5C A;  2FK6 A;  4NQ6 A;  4CHL A;  5EV6 A;  3H3E A;  4J5H A;  2YZ3 A;  3ZQ4 A;  4Z67 A;  4Z7R A;  5KIK A;  2BG2 A;  3KNS A;  5KIL A;  5A0T A;  3FAI A;  3IEM A;  5ACS A;  2H6A A;  5B1U A;  2FU9 A;  3T3N A;  2NXA A;  4C1C A;  5ACV A;  5HH6 A;  1KO2 A;  1M2X A;  4AX0 B;  4C1E A;  5HH4 A;  3AF6 A;  1YCF A;  1WRA A;  3A4Y A;  5A0V A;  2YNV B;  2BG8 A;  1SML A;  4TYT A;  4WD6 A;  4EFZ A;  4DIK A;  3S0Z A;  1ZTC A;  2XR1 A;  4AD9 A;  3DH8 A;  1KO3 A;  1DDK A;  1L9Y A;  3P2U A;  3RKJ A;  2NZE A;  4Z5Z A;  4FEK A;  3BK2 A;  3R2U A;  2WYM C;  2QJS A;  2BR6 A;  4D1V A;  4J5F A;  5LCA A;  3F9O A;  2QIN A;  4C1D A;  4UA4 A;  4JO0 A;  4LE6 A;  3SRX A;  2QDT A;  2YNT A;  3ZR9 A;  4XWT A;  2GFK A;  5LS3 A;  2QED A;  4AV7 A;  2AIO A;  5B15 A;  5B3R A;  5AYA A;  2BG7 A;  1X8H A;  2QDS A;  4FSB A;  4NQ2 A;  4ZNB A;  4H0D A;  5LMC A;  2OHH A;  1MQO A;  4YSB A;  4UAM A;  5FQC A;  1QH5 A;  4BP0 A;  2Y8B A;  4D1T A;  4ZEJ A;  2BG6 A;  4B87 A;  4EYF A;  1DD6 A;  3RPC A;  3AJ3 A;  2GKL A;  1BC2 A;  1JJE A;  3Q6V A;  2P97 A;  4GYU A;  4P62 A;  5EHT A;  5K0W A;  4PDX A;  1KR3 A;  4NQ4 A;  4TZB A;  2BGA A;  3IEL A;  1E5D A;  2I7V A;  5HIQ A;  2WHG A;  2WYM A;  5IQK A;  5EVB A;  1WW1 A;  3DHA A;  3ZNB A;  2BTN A;  4XUK A;  4EXS A;  3KL7 A;  3X2Z A;  3VPE A;  2ZWR A;  3BV6 A;  5K4N A;  4AXH A;  4TYF A;  4C1G A;  5DPX A;  4YSK A;  3X30 A;  3DHB A;  5K4M A;  4C09 A;  3IOF A;  2UYX A;  2BFK A;  4Z60 A;  4UWP B;  2WYL A;  3ESH A;  4KEP A;  3L6N A;  5EWA A;  3I15 A;  1VJN A;  4FR7 A;  1A7T A;  2BMI A;  4ZO3 A;  2GMN A;  4EXY A;  3QH8 A;  5K4K A;  4KEQ A;  3BC2 A;  4C1H A;  4D02 A;  4RAM A;  3RKK A;  4D1U A;  1JT1 A;  4PVO A;  1JJT A;  4RBS A;  1YCH A;  1VGN A;  4D1W A;  2OHJ A;  4UWR B;  4V0H A;  1P9E A;  3DHC A;  3IOG A;  4HL1 A;  2Q42 A;  3T3O A;  3JXP A;  5EV8 A;  2CG3 A;  5EVD A;  4UWS B;  3ZWF A;  5LCF A;  1WUP A;  3ADR A;  3FCZ A;  5HIP A;  5EW0 A;  3I14 A;  1VME A;  4TZ9 A;  2FM6 A;  4AX1 B;  5FQA A;  4TZE A;  5ACR A;  3PG4 A;  3BK1 A;  2Y87 A;  1K07 A;  4AWY B;  4XWW A;  4U4L A;  4YSL A;  3PY5 A;  4PVT A;  3SPU A;  3X2X A;  2AZ4 A;  2BG8 B;  2CG2 A;  2FU8 A;  1ZKP A;  1QH3 A;  2BFL A;  2P18 A;  4C1F A;  2ZO4 A;  1YCG A;  2FU7 A;  1BVT A;  4Z5Y A;  2XF4 A;  2YNV A;  2BIB A;  1ZNB A;  3KNR A;  3T9M A;  4O98 A;  2P4Z A;  1Y44 A;  2YNT B;  5AJL A;  1DXK A;  2BFZ A;  3WXC A;  4RL0 A;  2CFZ A;  4GCW A;  4DIL A;  2R2D A;  5EVK A;  3IEK A;  3PY6 A;  5HIS A;  3VQZ A;  1WUO A;  4TZF A;  3I0V A;  5LM6 A;  5FQB A;  3AF5 A;  4EYL A;  5AXO A;  2CBN A;  2VW8 A;  2NZF A;  3MD7 A; 
#chains in the Genus database with same CATH homology
 2I7X A;  2YNW A;  5LCH A;  5A87 A;  2NYP A;  3IE0 A;  2OHI A;  1X8I A;  4EYB A;  2Q9U A;  2E7Y A;  2M5D A;  1A8T A;  2WRS A;  5AXR A;  2DOO A;  1X8G A;  5LSC A;  2FHX A;  5A5Z A;  2FU6 A;  4GYQ A;  2DKF A;  4ZO2 A;  2Q0J A;  4AWZ A;  3IDZ A;  3TP9 A;  3SW3 A;  5AEB A;  3I11 A;  2A7M A;  2BFZ B;  2BC2 A;  4HL2 A;  5ACT A;  2P1E A;  5ACW A;  4EY2 A;  3IE2 A;  3SD9 A;  4RM5 A;  1XTO A;  4BZ3 A;  2Q0I A;  2Y8A A;  4NQ5 A;  5AHR A;  4UBQ A;  1HLK A;  2ZZI A;  2HB9 A;  2I7T A;  3SFP A;  5ACP A;  5LE1 A;  4RL2 A;  5ACX A;  3G1P A;  5EH9 A;  3X2Y A;  4F6Z A;  5HIO A;  4RAW A;  1BMC A;  1XM8 A;  4UWO B;  4HKY A;  5AHO A;  3LVZ A;  5ACQ A;  2ZNB A;  4Z6X A;  5HH5 A;  2GCU A;  2FHX B;  2YNU A;  4F6H A;  3I13 A;  5LLD A;  2YCB A;  5ACU A;  3IE1 A;  2GFJ A;  3SBL A;  2M5C A;  2FK6 A;  4NQ6 A;  4CHL A;  5EV6 A;  3H3E A;  4J5H A;  2YZ3 A;  3ZQ4 A;  4Z67 A;  4Z7R A;  5KIK A;  2BG2 A;  3KNS A;  5KIL A;  5A0T A;  3FAI A;  3IEM A;  5ACS A;  2H6A A;  5B1U A;  2FU9 A;  3T3N A;  2NXA A;  4C1C A;  5ACV A;  5HH6 A;  1KO2 A;  1M2X A;  4AX0 B;  4C1E A;  5HH4 A;  3AF6 A;  1YCF A;  1WRA A;  3A4Y A;  5A0V A;  2YNV B;  2BG8 A;  1SML A;  4TYT A;  4WD6 A;  4EFZ A;  4DIK A;  3S0Z A;  1ZTC A;  2XR1 A;  4AD9 A;  3DH8 A;  1KO3 A;  1DDK A;  1L9Y A;  3P2U A;  3RKJ A;  2NZE A;  4Z5Z A;  4FEK A;  3BK2 A;  3R2U A;  2WYM C;  2QJS A;  2BR6 A;  4D1V A;  4J5F A;  5LCA A;  3F9O A;  2QIN A;  4C1D A;  4UA4 A;  4JO0 A;  4LE6 A;  3SRX A;  2QDT A;  2YNT A;  3ZR9 A;  4XWT A;  2GFK A;  5LS3 A;  2QED A;  2AIO A;  5B15 A;  5B3R A;  5AYA A;  2BG7 A;  1X8H A;  2QDS A;  4FSB A;  4NQ2 A;  4ZNB A;  4H0D A;  5LMC A;  2OHH A;  1MQO A;  4YSB A;  4UAM A;  5FQC A;  1QH5 A;  4BP0 A;  2Y8B A;  4D1T A;  4ZEJ A;  2BG6 A;  4B87 A;  4EYF A;  1DD6 A;  3RPC A;  3AJ3 A;  2GKL A;  1BC2 A;  1JJE A;  3Q6V A;  2P97 A;  4GYU A;  4P62 A;  5EHT A;  5K0W A;  1KR3 A;  4NQ4 A;  4TZB A;  2BGA A;  3IEL A;  1E5D A;  2I7V A;  5HIQ A;  2WHG A;  2WYM A;  5IQK A;  5EVB A;  1WW1 A;  3DHA A;  3ZNB A;  2BTN A;  4XUK A;  4EXS A;  3KL7 A;  3X2Z A;  3VPE A;  2ZWR A;  3BV6 A;  5K4N A;  4TYF A;  4C1G A;  5DPX A;  4YSK A;  3X30 A;  3DHB A;  5K4M A;  4C09 A;  3IOF A;  2UYX A;  2BFK A;  4Z60 A;  4UWP B;  2WYL A;  3ESH A;  4KEP A;  3L6N A;  5EWA A;  3I15 A;  1VJN A;  4FR7 A;  1A7T A;  2BMI A;  4ZO3 A;  2GMN A;  4EXY A;  3QH8 A;  5K4K A;  4KEQ A;  3BC2 A;  4C1H A;  4D02 A;  4RAM A;  3RKK A;  4D1U A;  1JT1 A;  4PVO A;  1JJT A;  4RBS A;  1YCH A;  1VGN A;  4D1W A;  2OHJ A;  4UWR B;  4V0H A;  1P9E A;  3DHC A;  3IOG A;  4HL1 A;  2Q42 A;  3T3O A;  3JXP A;  5EV8 A;  5EVD A;  4UWS B;  3ZWF A;  5LCF A;  1WUP A;  3ADR A;  3FCZ A;  5HIP A;  5EW0 A;  3I14 A;  1VME A;  4TZ9 A;  2FM6 A;  4AX1 B;  5FQA A;  4TZE A;  5ACR A;  3PG4 A;  3BK1 A;  2Y87 A;  1K07 A;  4AWY B;  4XWW A;  4U4L A;  4YSL A;  3PY5 A;  4PVT A;  3SPU A;  3X2X A;  2AZ4 A;  2BG8 B;  2FU8 A;  1ZKP A;  1QH3 A;  2BFL A;  2P18 A;  4C1F A;  2ZO4 A;  1YCG A;  2FU7 A;  1BVT A;  4Z5Y A;  2XF4 A;  2YNV A;  2BIB A;  1ZNB A;  3KNR A;  3T9M A;  4O98 A;  2P4Z A;  1Y44 A;  2YNT B;  1DXK A;  2BFZ A;  3WXC A;  4RL0 A;  4GCW A;  4DIL A;  2R2D A;  5EVK A;  3IEK A;  3PY6 A;  5HIS A;  3VQZ A;  1WUO A;  4TZF A;  3I0V A;  5LM6 A;  5FQB A;  3AF5 A;  4EYL A;  5AXO A;  2CBN A;  2VW8 A;  2NZF A;  3MD7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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