5ACWA

Vim-2-1, discovery of novel inhibitor scaffolds against the metallo- beta-lactamase vim-2 by spr based fragment screening
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
233
structure length
232
Chain Sequence
GEYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNRS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords BETA-LACTAMASE
publication title Discovery of Novel Inhibitor Scaffolds Against the Metallo-Beta-Lactamase Vim-2 by Spr Based Fragment Screening
pubmed doi rcsb
source organism Pseudomonas aeruginosa
total genus 73
structure length 232
sequence length 233
chains with identical sequence B
ec nomenclature ec 3.5.2.6: Beta-lactamase.
pdb deposition date 2015-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5acwA00
5HH5A 2YNWA 4C1CA 1VGNA 2BMIA 4KEQA 5K4NA 4ZNBA 5AHOA 1BVTA 3SW3A 4UWPB 5EV6A 5AYAA 5FQCA 4EXSA 4U4LA 1ZTCA 3R2UA 3SFPA 5ACXA 3SPUA 1YCGA 3T3NA 3FAIA 2FU7A 5AEBA 5HIQA 4XWTA 1L9YA 4GYUA 4EXYA 4C1GA 1X8IA 3RKKA 2WYMA 4UWRB 4C1FA 4HL1A 4WD6A 2BIBA 3SRXA 4GCWA 1E5DA 2WYLA 2BR6A 3X30A 2ZZIA 2NZEA 2R2DA 2BGAA 2FHXA 2P1EA 3I11A 1WRAA 4Z6XA 3X2XA 4EYFA 4RL2A 4UWOB 2BG6A 4TZEA 4Z5YA 3Q6VA 2VW8A 4D1UA 1JJEA 5LSCA 2BC2A 4UBQA 4UA4A 2NYPA 2YNTA 5ACSA 2E7YA 3IEMA 4UAMA 3IE0A 4YSKA 3H3EA 2GKLA 2A7MA 3T9MA 2Y8AA 4TZFA 3IEKA 1KO2A 3IOGA 5LCAA 5HH4A 2BG8B 2Y8BA 5EW0A 4AWZA 2FK6A 1DD6A 1X8GA 5AHRA 5FQAA 3AF5A 4RL0A 3ZWFA 3ZNBA 2FU6A 2YNUA 1QH5A 4EYLA 3ZQ4A 1DXKA 1XTOA 2Y87A 4EYBA 3AJ3A 2XR1A 5B15A 5EVDA 1XM8A 5LCHA 2FM6A 1KR3A 2QEDA 4O98A 4H0DA 4P62A 2M5CA 1X8HA 1WW1A 2ZNBA 4HKYA 3T3OA 2ZO4A 2GCUA 1BC2A 3RPCA 2WHGA 2QDSA 2Q0JA 3BV6A 5K0WA 2NZFA 3DHCA 5AXOA 1YCHA 2BFLA 5A0TA 2DOOA 2BFKA 4J5HA 3ADRA 3BC2A 5HIOA 4Z5ZA 4ZO2A 3QH8A 4XUKA 4Z67A 2YCBA 5EH9A 4D02A 4DILA 2UYXA 3SBLA 3IE2A 4XWWA 4ZO3A 4GYQA 4RBSA 5A87A 2M5DA 1DDKA 2HB9A 2WYMC 1Y44A 3I15A 2CBNA 5ACUA 5B3RA 5EVBA 2YNVA 2OHJA 1MQOA 5LLDA 5LMCA 2AZ4A 1HLKA 4PVTA 3I14A 4LE6A 1YCFA 2FHXB 2OHHA 5A5ZA 2I7XA 3BK1A 4D1WA 4NQ4A 5EHTA 3AF6A 4TZBA 1JJTA 5ACTA 2P97A 4F6ZA 1ZKPA 4RAMA 4NQ5A 4UWSB 4AWYB 3MD7A 4BZ3A 2YNTB 2GFJA 5HISA 5LE1A 1VMEA 2Q0IA 2BTNA 4RM5A 4V0HA 4F6HA 3IDZA 4C09A 2WRSA 5HH6A 3PY5A 3IE1A 1A7TA 3VQZA 3LVZA 3ESHA 2GFKA 2Q9UA 4TYTA 5ACPA 2FU8A 4PVOA 2ZWRA 3F9OA 3P2UA 4Z60A 3DHAA 5ACVA 4TZ9A 5LCFA 2H6AA 3KNSA 5HIPA 2XF4A 4JO0A 2BFZB 4EFZA 4EY2A 1VJNA 3PY6A 2AIOA 2P18A 4FSBA 3G1PA 3X2ZA 4B87A 1WUPA 3SD9A 3WXCA 4YSLA 3RKJA 5DPXA 5ACWA 4RAWA 3FCZA 3X2YA 4DIKA 4NQ6A 3I13A 1BMCA 3DHBA 2OHIA 3KL7A 5IQKA 5K4MA 2YZ3A 1JT1A 4FR7A 4C1DA 5EWAA 1P9EA 5EVKA 4TYFA 4AD9A 4D1VA 3S0ZA 5LS3A 5ACQA 3KNRA 2FU9A 2I7VA 4J5FA 4KEPA 1K07A 4AX0B 5EV8A 4C1EA 4CHLA 4C1HA 2BG8A 3JXPA 1ZNBA 3ZR9A 2GMNA 1WUOA 3PG4A 4AX1B 1SMLA 4BP0A 2Q42A 2DKFA 2QDTA 4YSBA 1A8TA 3A4YA 3I0VA 3IOFA 2YNVB 5KIKA 2P4ZA 3VPEA 1KO3A 2BG2A 3IELA 3L6NA 5K4KA 2QINA 5A0VA 4NQ2A 4D1TA 5B1UA 3BK2A 5ACRA 4FEKA 5LM6A 4ZEJA 4HL2A 2QJSA 5FQBA 1QH3A 4Z7RA 2I7TA 5KILA 2BG7A 3DH8A 3TP9A 1M2XA 2NXAA 2BFZA 5AXRA
chains in the Genus database with same CATH superfamily
5HH5A 2YNWA 4C1CA 1VGNA 2BMIA 4KEQA 5K4NA 4ZNBA 5AHOA 1BVTA 3SW3A 4UWPB 5EV6A 5AYAA 5FQCA 4EXSA 4U4LA 1ZTCA 3R2UA 3SFPA 5ACXA 3SPUA 1YCGA 3T3NA 3FAIA 2FU7A 5AEBA 4AXHA 5HIQA 4XWTA 1L9YA 4GYUA 4EXYA 4C1GA 1X8IA 3RKKA 2WYMA 4UWRB 4C1FA 4HL1A 4WD6A 2BIBA 3SRXA 4GCWA 1E5DA 2WYLA 2BR6A 3X30A 2ZZIA 2NZEA 2R2DA 2BGAA 2FHXA 2P1EA 3I11A 1WRAA 4Z6XA 3X2XA 4EYFA 4RL2A 4UWOB 2BG6A 4TZEA 4Z5YA 3Q6VA 2VW8A 4D1UA 1JJEA 5LSCA 2BC2A 4UBQA 4UA4A 2NYPA 2YNTA 5ACSA 2E7YA 3IEMA 4UAMA 3IE0A 4YSKA 3H3EA 2GKLA 2YHEA 2A7MA 3T9MA 2Y8AA 4TZFA 3IEKA 4AV7A 1KO2A 3IOGA 5LCAA 5HH4A 2BG8B 2Y8BA 5EW0A 4AWZA 2FK6A 1DD6A 1X8GA 5AHRA 5FQAA 3AF5A 4RL0A 3ZWFA 3ZNBA 2FU6A 2YNUA 1QH5A 4EYLA 3ZQ4A 1DXKA 1XTOA 2Y87A 4EYBA 3AJ3A 2XR1A 5B15A 5EVDA 1XM8A 5LCHA 2FM6A 1KR3A 2QEDA 4O98A 4H0DA 4P62A 2M5CA 1X8HA 1WW1A 2ZNBA 4PDXA 4HKYA 3T3OA 2ZO4A 2GCUA 1BC2A 3RPCA 2WHGA 2QDSA 2Q0JA 3BV6A 5K0WA 2NZFA 3DHCA 5AXOA 1YCHA 2BFLA 5A23A 5A0TA 2DOOA 2BFKA 4J5HA 3ADRA 3BC2A 5HIOA 4Z5ZA 4ZO2A 3QH8A 4XUKA 4Z67A 2YCBA 5EH9A 4D02A 4DILA 2UYXA 3SBLA 3IE2A 4XWWA 4ZO3A 4GYQA 5AIJA 4RBSA 5A87A 2M5DA 1DDKA 2HB9A 2WYMC 2CG3A 1Y44A 3I15A 2CBNA 5ACUA 5B3RA 5EVBA 4NURA 2YNVA 2CFZA 2OHJA 1MQOA 5LLDA 5LMCA 2AZ4A 1HLKA 4PVTA 3I14A 4LE6A 1YCFA 2FHXB 2OHHA 5A5ZA 2I7XA 3BK1A 4D1WA 4NQ4A 5EHTA 3AF6A 4TZBA 1JJTA 5ACTA 2P97A 4F6ZA 1ZKPA 4RAMA 4NQ5A 4UWSB 4AWYB 3MD7A 4BZ3A 2YNTB 2GFJA 5HISA 5LE1A 1VMEA 2Q0IA 2BTNA 4RM5A 4V0HA 4F6HA 3IDZA 4C09A 2WRSA 5HH6A 3PY5A 3IE1A 1A7TA 3VQZA 3LVZA 3ESHA 2GFKA 2Q9UA 4TYTA 5ACPA 2FU8A 4PVOA 2ZWRA 3F9OA 3P2UA 4Z60A 3DHAA 5ACVA 4TZ9A 5LCFA 2H6AA 3KNSA 5HIPA 2XF4A 4JO0A 2BFZB 4EFZA 4EY2A 1VJNA 3PY6A 2AIOA 2P18A 4FSBA 3G1PA 3X2ZA 4B87A 1WUPA 3SD9A 3WXCA 4YSLA 3RKJA 5DPXA 5ACWA 4RAWA 3FCZA 3X2YA 4DIKA 4NQ6A 3I13A 1BMCA 3DHBA 2OHIA 3KL7A 5AJLA 5IQKA 5K4MA 2YZ3A 1JT1A 4FR7A 4C1DA 5EWAA 1P9EA 5EVKA 4TYFA 4AD9A 4D1VA 3S0ZA 5LS3A 2CG2A 5ACQA 3KNRA 2FU9A 2I7VA 4J5FA 4KEPA 1K07A 4AX0B 5EV8A 4C1EA 4CHLA 4C1HA 2BG8A 3JXPA 1ZNBA 3ZR9A 2GMNA 1WUOA 3PG4A 4AX1B 1SMLA 4BP0A 2Q42A 2DKFA 2QDTA 4YSBA 1A8TA 3A4YA 3I0VA 3IOFA 2YNVB 5KIKA 2P4ZA 3VPEA 1KO3A 2BG2A 3IELA 3L6NA 5K4KA 2QINA 5A0VA 4NQ2A 4D1TA 5B1UA 3BK2A 5ACRA 4FEKA 5LM6A 4ZEJA 4HL2A 2QJSA 5FQBA 1QH3A 4Z7RA 2I7TA 5KILA 2BG7A 3TP9A 3DH8A 1M2XA 2CFUA 2NXAA 2BFZA 5AXRA
chains in the Genus database with same CATH topology
5HH5A 2YNWA 4C1CA 1VGNA 2BMIA 4KEQA 5K4NA 4ZNBA 5AHOA 1BVTA 3SW3A 4UWPB 5EV6A 5AYAA 5FQCA 4EXSA 4U4LA 1ZTCA 3R2UA 3SFPA 5ACXA 3SPUA 1YCGA 3T3NA 3FAIA 2FU7A 5AEBA 5HIQA 4XWTA 1L9YA 4GYUA 4EXYA 4C1GA 1X8IA 3RKKA 2WYMA 4UWRB 4C1FA 4HL1A 4WD6A 2BIBA 3SRXA 4GCWA 1E5DA 2WYLA 2BR6A 3X30A 2ZZIA 2NZEA 2R2DA 2BGAA 2FHXA 2P1EA 3I11A 1WRAA 4Z6XA 3X2XA 4EYFA 4RL2A 4UWOB 2BG6A 4TZEA 4Z5YA 3Q6VA 2VW8A 4D1UA 1JJEA 5LSCA 2BC2A 4UBQA 4UA4A 2NYPA 2YNTA 5ACSA 2E7YA 3IEMA 4UAMA 3IE0A 4YSKA 3H3EA 2GKLA 2A7MA 3T9MA 2Y8AA 4TZFA 3IEKA 1KO2A 3IOGA 5LCAA 5HH4A 2BG8B 2Y8BA 5EW0A 4AWZA 2FK6A 1DD6A 1X8GA 5AHRA 5FQAA 3AF5A 4RL0A 3ZWFA 3ZNBA 2FU6A 2YNUA 1QH5A 4EYLA 3ZQ4A 1DXKA 1XTOA 2Y87A 4EYBA 3AJ3A 2XR1A 5B15A 5EVDA 1XM8A 5LCHA 2FM6A 1KR3A 2QEDA 4O98A 4H0DA 4P62A 2M5CA 1X8HA 1WW1A 2ZNBA 4HKYA 3T3OA 2ZO4A 2GCUA 1BC2A 3RPCA 2WHGA 2QDSA 2Q0JA 3BV6A 5K0WA 2NZFA 3DHCA 5AXOA 1YCHA 2BFLA 5A0TA 2DOOA 2BFKA 4J5HA 3ADRA 3BC2A 5HIOA 4Z5ZA 4ZO2A 3QH8A 4XUKA 4Z67A 2YCBA 5EH9A 4D02A 4DILA 2UYXA 3SBLA 3IE2A 4XWWA 4ZO3A 4GYQA 4RBSA 5A87A 2M5DA 1DDKA 2HB9A 2WYMC 1Y44A 3I15A 2CBNA 5ACUA 5B3RA 5EVBA 2YNVA 2OHJA 1MQOA 5LLDA 5LMCA 2AZ4A 1HLKA 4PVTA 3I14A 4LE6A 1YCFA 2FHXB 2OHHA 5A5ZA 2I7XA 3BK1A 4D1WA 4NQ4A 5EHTA 3AF6A 4TZBA 1JJTA 5ACTA 2P97A 4F6ZA 1ZKPA 4RAMA 4NQ5A 4UWSB 4AWYB 3MD7A 4BZ3A 2YNTB 2GFJA 5HISA 5LE1A 1VMEA 2Q0IA 2BTNA 4RM5A 4V0HA 4F6HA 3IDZA 4C09A 2WRSA 5HH6A 3PY5A 3IE1A 1A7TA 3VQZA 3LVZA 3ESHA 2GFKA 2Q9UA 4TYTA 5ACPA 2FU8A 4PVOA 2ZWRA 3F9OA 3P2UA 4Z60A 3DHAA 5ACVA 4TZ9A 5LCFA 2H6AA 3KNSA 5HIPA 2XF4A 4JO0A 2BFZB 4EFZA 4EY2A 1VJNA 3PY6A 2AIOA 2P18A 4FSBA 3G1PA 3X2ZA 4B87A 1WUPA 3SD9A 3WXCA 4YSLA 3RKJA 5DPXA 5ACWA 4RAWA 3FCZA 3X2YA 4DIKA 4NQ6A 3I13A 1BMCA 3DHBA 2OHIA 3KL7A 5IQKA 5K4MA 2YZ3A 1JT1A 4FR7A 4C1DA 5EWAA 1P9EA 5EVKA 4TYFA 4AD9A 4D1VA 3S0ZA 5LS3A 5ACQA 3KNRA 2FU9A 2I7VA 4J5FA 4KEPA 1K07A 4AX0B 5EV8A 4C1EA 4CHLA 4C1HA 2BG8A 3JXPA 1ZNBA 3ZR9A 2GMNA 1WUOA 3PG4A 4AX1B 1SMLA 4BP0A 2Q42A 2DKFA 2QDTA 4YSBA 1A8TA 3A4YA 3I0VA 3IOFA 2YNVB 5KIKA 2P4ZA 3VPEA 1KO3A 2BG2A 3IELA 3L6NA 5K4KA 2QINA 5A0VA 4NQ2A 4D1TA 5B1UA 3BK2A 5ACRA 4FEKA 5LM6A 4ZEJA 4HL2A 2QJSA 5FQBA 1QH3A 4Z7RA 2I7TA 5KILA 2BG7A 3DH8A 3TP9A 1M2XA 2NXAA 2BFZA 5AXRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HH5 A;  2YNW A;  4C1C A;  1VGN A;  2BMI A;  4KEQ A;  5K4N A;  4ZNB A;  5AHO A;  1BVT A;  3SW3 A;  4UWP B;  5EV6 A;  5AYA A;  5FQC A;  4EXS A;  4U4L A;  1ZTC A;  3R2U A;  3SFP A;  5ACX A;  3SPU A;  1YCG A;  3T3N A;  3FAI A;  2FU7 A;  5AEB A;  5HIQ A;  4XWT A;  1L9Y A;  4GYU A;  4EXY A;  4C1G A;  1X8I A;  3RKK A;  2WYM A;  4UWR B;  4C1F A;  4HL1 A;  4WD6 A;  2BIB A;  3SRX A;  4GCW A;  1E5D A;  2WYL A;  2BR6 A;  3X30 A;  2ZZI A;  2NZE A;  2R2D A;  2BGA A;  2FHX A;  2P1E A;  3I11 A;  1WRA A;  4Z6X A;  3X2X A;  4EYF A;  4RL2 A;  4UWO B;  2BG6 A;  4TZE A;  4Z5Y A;  3Q6V A;  2VW8 A;  4D1U A;  1JJE A;  5LSC A;  2BC2 A;  4UBQ A;  4UA4 A;  2NYP A;  2YNT A;  5ACS A;  2E7Y A;  3IEM A;  4UAM A;  3IE0 A;  4YSK A;  3H3E A;  2GKL A;  2A7M A;  3T9M A;  2Y8A A;  4TZF A;  3IEK A;  1KO2 A;  3IOG A;  5LCA A;  5HH4 A;  2BG8 B;  2Y8B A;  5EW0 A;  4AWZ A;  2FK6 A;  1DD6 A;  1X8G A;  5AHR A;  5FQA A;  3AF5 A;  4RL0 A;  3ZWF A;  3ZNB A;  2FU6 A;  2YNU A;  1QH5 A;  4EYL A;  3ZQ4 A;  1DXK A;  1XTO A;  2Y87 A;  4EYB A;  3AJ3 A;  2XR1 A;  5B15 A;  5EVD A;  1XM8 A;  5LCH A;  2FM6 A;  1KR3 A;  2QED A;  4O98 A;  4H0D A;  4P62 A;  2M5C A;  1X8H A;  1WW1 A;  2ZNB A;  4HKY A;  3T3O A;  2ZO4 A;  2GCU A;  1BC2 A;  3RPC A;  2WHG A;  2QDS A;  2Q0J A;  3BV6 A;  5K0W A;  2NZF A;  3DHC A;  5AXO A;  1YCH A;  2BFL A;  5A0T A;  2DOO A;  2BFK A;  4J5H A;  3ADR A;  3BC2 A;  5HIO A;  4Z5Z A;  4ZO2 A;  3QH8 A;  4XUK A;  4Z67 A;  2YCB A;  5EH9 A;  4D02 A;  4DIL A;  2UYX A;  3SBL A;  3IE2 A;  4XWW A;  4ZO3 A;  4GYQ A;  4RBS A;  5A87 A;  2M5D A;  1DDK A;  2HB9 A;  2WYM C;  1Y44 A;  3I15 A;  2CBN A;  5ACU A;  5B3R A;  5EVB A;  2YNV A;  2OHJ A;  1MQO A;  5LLD A;  5LMC A;  2AZ4 A;  1HLK A;  4PVT A;  3I14 A;  4LE6 A;  1YCF A;  2FHX B;  2OHH A;  5A5Z A;  2I7X A;  3BK1 A;  4D1W A;  4NQ4 A;  5EHT A;  3AF6 A;  4TZB A;  1JJT A;  5ACT A;  2P97 A;  4F6Z A;  1ZKP A;  4RAM A;  4NQ5 A;  4UWS B;  4AWY B;  3MD7 A;  4BZ3 A;  2YNT B;  2GFJ A;  5HIS A;  5LE1 A;  1VME A;  2Q0I A;  2BTN A;  4RM5 A;  4V0H A;  4F6H A;  3IDZ A;  4C09 A;  2WRS A;  5HH6 A;  3PY5 A;  3IE1 A;  1A7T A;  3VQZ A;  3LVZ A;  3ESH A;  2GFK A;  2Q9U A;  4TYT A;  5ACP A;  2FU8 A;  4PVO A;  2ZWR A;  3F9O A;  3P2U A;  4Z60 A;  3DHA A;  5ACV A;  4TZ9 A;  5LCF A;  2H6A A;  3KNS A;  5HIP A;  2XF4 A;  4JO0 A;  2BFZ B;  4EFZ A;  4EY2 A;  1VJN A;  3PY6 A;  2AIO A;  2P18 A;  4FSB A;  3G1P A;  3X2Z A;  4B87 A;  1WUP A;  3SD9 A;  3WXC A;  4YSL A;  3RKJ A;  5DPX A;  5ACW A;  4RAW A;  3FCZ A;  3X2Y A;  4DIK A;  4NQ6 A;  3I13 A;  1BMC A;  3DHB A;  2OHI A;  3KL7 A;  5IQK A;  5K4M A;  2YZ3 A;  1JT1 A;  4FR7 A;  4C1D A;  5EWA A;  1P9E A;  5EVK A;  4TYF A;  4AD9 A;  4D1V A;  3S0Z A;  5LS3 A;  5ACQ A;  3KNR A;  2FU9 A;  2I7V A;  4J5F A;  4KEP A;  1K07 A;  4AX0 B;  5EV8 A;  4C1E A;  4CHL A;  4C1H A;  2BG8 A;  3JXP A;  1ZNB A;  3ZR9 A;  2GMN A;  1WUO A;  3PG4 A;  4AX1 B;  1SML A;  4BP0 A;  2Q42 A;  2DKF A;  2QDT A;  4YSB A;  1A8T A;  3A4Y A;  3I0V A;  3IOF A;  2YNV B;  5KIK A;  2P4Z A;  3VPE A;  1KO3 A;  2BG2 A;  3IEL A;  3L6N A;  5K4K A;  2QIN A;  5A0V A;  4NQ2 A;  4D1T A;  5B1U A;  3BK2 A;  5ACR A;  4FEK A;  5LM6 A;  4ZEJ A;  4HL2 A;  2QJS A;  5FQB A;  1QH3 A;  4Z7R A;  2I7T A;  5KIL A;  2BG7 A;  3DH8 A;  3TP9 A;  1M2X A;  2NXA A;  2BFZ A;  5AXR A; 
#chains in the Genus database with same CATH topology
 5HH5 A;  2YNW A;  4C1C A;  1VGN A;  2BMI A;  4KEQ A;  5K4N A;  4ZNB A;  5AHO A;  1BVT A;  3SW3 A;  4UWP B;  5EV6 A;  5AYA A;  5FQC A;  4EXS A;  4U4L A;  1ZTC A;  3R2U A;  3SFP A;  5ACX A;  3SPU A;  1YCG A;  3T3N A;  3FAI A;  2FU7 A;  5AEB A;  4AXH A;  5HIQ A;  4XWT A;  1L9Y A;  4GYU A;  4EXY A;  4C1G A;  1X8I A;  3RKK A;  2WYM A;  4UWR B;  4C1F A;  4HL1 A;  4WD6 A;  2BIB A;  3SRX A;  4GCW A;  1E5D A;  2WYL A;  2BR6 A;  3X30 A;  2ZZI A;  2NZE A;  2R2D A;  2BGA A;  2FHX A;  2P1E A;  3I11 A;  1WRA A;  4Z6X A;  3X2X A;  4EYF A;  4RL2 A;  4UWO B;  2BG6 A;  4TZE A;  4Z5Y A;  3Q6V A;  2VW8 A;  4D1U A;  1JJE A;  5LSC A;  2BC2 A;  4UBQ A;  4UA4 A;  2NYP A;  2YNT A;  5ACS A;  2E7Y A;  3IEM A;  4UAM A;  3IE0 A;  4YSK A;  3H3E A;  2GKL A;  2YHE A;  2A7M A;  3T9M A;  2Y8A A;  4TZF A;  3IEK A;  4AV7 A;  1KO2 A;  3IOG A;  5LCA A;  5HH4 A;  2BG8 B;  2Y8B A;  5EW0 A;  4AWZ A;  2FK6 A;  1DD6 A;  1X8G A;  5AHR A;  5FQA A;  3AF5 A;  4RL0 A;  3ZWF A;  3ZNB A;  2FU6 A;  2YNU A;  1QH5 A;  4EYL A;  3ZQ4 A;  1DXK A;  1XTO A;  2Y87 A;  4EYB A;  3AJ3 A;  2XR1 A;  5B15 A;  5EVD A;  1XM8 A;  5LCH A;  2FM6 A;  1KR3 A;  2QED A;  4O98 A;  4H0D A;  4P62 A;  2M5C A;  1X8H A;  1WW1 A;  2ZNB A;  4PDX A;  4HKY A;  3T3O A;  2ZO4 A;  2GCU A;  1BC2 A;  3RPC A;  2WHG A;  2QDS A;  2Q0J A;  3BV6 A;  5K0W A;  2NZF A;  3DHC A;  5AXO A;  1YCH A;  2BFL A;  5A23 A;  5A0T A;  2DOO A;  2BFK A;  4J5H A;  3ADR A;  3BC2 A;  5HIO A;  4Z5Z A;  4ZO2 A;  3QH8 A;  4XUK A;  4Z67 A;  2YCB A;  5EH9 A;  4D02 A;  4DIL A;  2UYX A;  3SBL A;  3IE2 A;  4XWW A;  4ZO3 A;  4GYQ A;  5AIJ A;  4RBS A;  5A87 A;  2M5D A;  1DDK A;  2HB9 A;  2WYM C;  2CG3 A;  1Y44 A;  3I15 A;  2CBN A;  5ACU A;  5B3R A;  5EVB A;  4NUR A;  2YNV A;  2CFZ A;  2OHJ A;  1MQO A;  5LLD A;  5LMC A;  2AZ4 A;  1HLK A;  4PVT A;  3I14 A;  4LE6 A;  1YCF A;  2FHX B;  2OHH A;  5A5Z A;  2I7X A;  3BK1 A;  4D1W A;  4NQ4 A;  5EHT A;  3AF6 A;  4TZB A;  1JJT A;  5ACT A;  2P97 A;  4F6Z A;  1ZKP A;  4RAM A;  4NQ5 A;  4UWS B;  4AWY B;  3MD7 A;  4BZ3 A;  2YNT B;  2GFJ A;  5HIS A;  5LE1 A;  1VME A;  2Q0I A;  2BTN A;  4RM5 A;  4V0H A;  4F6H A;  3IDZ A;  4C09 A;  2WRS A;  5HH6 A;  3PY5 A;  3IE1 A;  1A7T A;  3VQZ A;  3LVZ A;  3ESH A;  2GFK A;  2Q9U A;  4TYT A;  5ACP A;  2FU8 A;  4PVO A;  2ZWR A;  3F9O A;  3P2U A;  4Z60 A;  3DHA A;  5ACV A;  4TZ9 A;  5LCF A;  2H6A A;  3KNS A;  5HIP A;  2XF4 A;  4JO0 A;  2BFZ B;  4EFZ A;  4EY2 A;  1VJN A;  3PY6 A;  2AIO A;  2P18 A;  4FSB A;  3G1P A;  3X2Z A;  4B87 A;  1WUP A;  3SD9 A;  3WXC A;  4YSL A;  3RKJ A;  5DPX A;  5ACW A;  4RAW A;  3FCZ A;  3X2Y A;  4DIK A;  4NQ6 A;  3I13 A;  1BMC A;  3DHB A;  2OHI A;  3KL7 A;  5AJL A;  5IQK A;  5K4M A;  2YZ3 A;  1JT1 A;  4FR7 A;  4C1D A;  5EWA A;  1P9E A;  5EVK A;  4TYF A;  4AD9 A;  4D1V A;  3S0Z A;  5LS3 A;  2CG2 A;  5ACQ A;  3KNR A;  2FU9 A;  2I7V A;  4J5F A;  4KEP A;  1K07 A;  4AX0 B;  5EV8 A;  4C1E A;  4CHL A;  4C1H A;  2BG8 A;  3JXP A;  1ZNB A;  3ZR9 A;  2GMN A;  1WUO A;  3PG4 A;  4AX1 B;  1SML A;  4BP0 A;  2Q42 A;  2DKF A;  2QDT A;  4YSB A;  1A8T A;  3A4Y A;  3I0V A;  3IOF A;  2YNV B;  5KIK A;  2P4Z A;  3VPE A;  1KO3 A;  2BG2 A;  3IEL A;  3L6N A;  5K4K A;  2QIN A;  5A0V A;  4NQ2 A;  4D1T A;  5B1U A;  3BK2 A;  5ACR A;  4FEK A;  5LM6 A;  4ZEJ A;  4HL2 A;  2QJS A;  5FQB A;  1QH3 A;  4Z7R A;  2I7T A;  5KIL A;  2BG7 A;  3TP9 A;  3DH8 A;  1M2X A;  2CFU A;  2NXA A;  2BFZ A;  5AXR A; 
#chains in the Genus database with same CATH homology
 5HH5 A;  2YNW A;  4C1C A;  1VGN A;  2BMI A;  4KEQ A;  5K4N A;  4ZNB A;  5AHO A;  1BVT A;  3SW3 A;  4UWP B;  5EV6 A;  5AYA A;  5FQC A;  4EXS A;  4U4L A;  1ZTC A;  3R2U A;  3SFP A;  5ACX A;  3SPU A;  1YCG A;  3T3N A;  3FAI A;  2FU7 A;  5AEB A;  5HIQ A;  4XWT A;  1L9Y A;  4GYU A;  4EXY A;  4C1G A;  1X8I A;  3RKK A;  2WYM A;  4UWR B;  4C1F A;  4HL1 A;  4WD6 A;  2BIB A;  3SRX A;  4GCW A;  1E5D A;  2WYL A;  2BR6 A;  3X30 A;  2ZZI A;  2NZE A;  2R2D A;  2BGA A;  2FHX A;  2P1E A;  3I11 A;  1WRA A;  4Z6X A;  3X2X A;  4EYF A;  4RL2 A;  4UWO B;  2BG6 A;  4TZE A;  4Z5Y A;  3Q6V A;  2VW8 A;  4D1U A;  1JJE A;  5LSC A;  2BC2 A;  4UBQ A;  4UA4 A;  2NYP A;  2YNT A;  5ACS A;  2E7Y A;  3IEM A;  4UAM A;  3IE0 A;  4YSK A;  3H3E A;  2GKL A;  2A7M A;  3T9M A;  2Y8A A;  4TZF A;  3IEK A;  1KO2 A;  3IOG A;  5LCA A;  5HH4 A;  2BG8 B;  2Y8B A;  5EW0 A;  4AWZ A;  2FK6 A;  1DD6 A;  1X8G A;  5AHR A;  5FQA A;  3AF5 A;  4RL0 A;  3ZWF A;  3ZNB A;  2FU6 A;  2YNU A;  1QH5 A;  4EYL A;  3ZQ4 A;  1DXK A;  1XTO A;  2Y87 A;  4EYB A;  3AJ3 A;  2XR1 A;  5B15 A;  5EVD A;  1XM8 A;  5LCH A;  2FM6 A;  1KR3 A;  2QED A;  4O98 A;  4H0D A;  4P62 A;  2M5C A;  1X8H A;  1WW1 A;  2ZNB A;  4HKY A;  3T3O A;  2ZO4 A;  2GCU A;  1BC2 A;  3RPC A;  2WHG A;  2QDS A;  2Q0J A;  3BV6 A;  5K0W A;  2NZF A;  3DHC A;  5AXO A;  1YCH A;  2BFL A;  5A0T A;  2DOO A;  2BFK A;  4J5H A;  3ADR A;  3BC2 A;  5HIO A;  4Z5Z A;  4ZO2 A;  3QH8 A;  4XUK A;  4Z67 A;  2YCB A;  5EH9 A;  4D02 A;  4DIL A;  2UYX A;  3SBL A;  3IE2 A;  4XWW A;  4ZO3 A;  4GYQ A;  4RBS A;  5A87 A;  2M5D A;  1DDK A;  2HB9 A;  2WYM C;  1Y44 A;  3I15 A;  2CBN A;  5ACU A;  5B3R A;  5EVB A;  2YNV A;  2OHJ A;  1MQO A;  5LLD A;  5LMC A;  2AZ4 A;  1HLK A;  4PVT A;  3I14 A;  4LE6 A;  1YCF A;  2FHX B;  2OHH A;  5A5Z A;  2I7X A;  3BK1 A;  4D1W A;  4NQ4 A;  5EHT A;  3AF6 A;  4TZB A;  1JJT A;  5ACT A;  2P97 A;  4F6Z A;  1ZKP A;  4RAM A;  4NQ5 A;  4UWS B;  4AWY B;  3MD7 A;  4BZ3 A;  2YNT B;  2GFJ A;  5HIS A;  5LE1 A;  1VME A;  2Q0I A;  2BTN A;  4RM5 A;  4V0H A;  4F6H A;  3IDZ A;  4C09 A;  2WRS A;  5HH6 A;  3PY5 A;  3IE1 A;  1A7T A;  3VQZ A;  3LVZ A;  3ESH A;  2GFK A;  2Q9U A;  4TYT A;  5ACP A;  2FU8 A;  4PVO A;  2ZWR A;  3F9O A;  3P2U A;  4Z60 A;  3DHA A;  5ACV A;  4TZ9 A;  5LCF A;  2H6A A;  3KNS A;  5HIP A;  2XF4 A;  4JO0 A;  2BFZ B;  4EFZ A;  4EY2 A;  1VJN A;  3PY6 A;  2AIO A;  2P18 A;  4FSB A;  3G1P A;  3X2Z A;  4B87 A;  1WUP A;  3SD9 A;  3WXC A;  4YSL A;  3RKJ A;  5DPX A;  5ACW A;  4RAW A;  3FCZ A;  3X2Y A;  4DIK A;  4NQ6 A;  3I13 A;  1BMC A;  3DHB A;  2OHI A;  3KL7 A;  5IQK A;  5K4M A;  2YZ3 A;  1JT1 A;  4FR7 A;  4C1D A;  5EWA A;  1P9E A;  5EVK A;  4TYF A;  4AD9 A;  4D1V A;  3S0Z A;  5LS3 A;  5ACQ A;  3KNR A;  2FU9 A;  2I7V A;  4J5F A;  4KEP A;  1K07 A;  4AX0 B;  5EV8 A;  4C1E A;  4CHL A;  4C1H A;  2BG8 A;  3JXP A;  1ZNB A;  3ZR9 A;  2GMN A;  1WUO A;  3PG4 A;  4AX1 B;  1SML A;  4BP0 A;  2Q42 A;  2DKF A;  2QDT A;  4YSB A;  1A8T A;  3A4Y A;  3I0V A;  3IOF A;  2YNV B;  5KIK A;  2P4Z A;  3VPE A;  1KO3 A;  2BG2 A;  3IEL A;  3L6N A;  5K4K A;  2QIN A;  5A0V A;  4NQ2 A;  4D1T A;  5B1U A;  3BK2 A;  5ACR A;  4FEK A;  5LM6 A;  4ZEJ A;  4HL2 A;  2QJS A;  5FQB A;  1QH3 A;  4Z7R A;  2I7T A;  5KIL A;  2BG7 A;  3DH8 A;  3TP9 A;  1M2X A;  2NXA A;  2BFZ A;  5AXR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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