5ACWA

Vim-2-1, discovery of novel inhibitor scaffolds against the metallo- beta-lactamase vim-2 by spr based fragment screening
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
233
structure length
232
Chain Sequence
GEYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNRS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords BETA-LACTAMASE
publication title Discovery of Novel Inhibitor Scaffolds Against the Metallo-Beta-Lactamase Vim-2 by Spr Based Fragment Screening
pubmed doi rcsb
source organism Pseudomonas aeruginosa
molecule tags Hydrolase
total genus 73
structure length 232
sequence length 233
chains with identical sequence B
ec nomenclature ec 3.5.2.6: Beta-lactamase.
pdb deposition date 2015-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5acwA00
3P2UA 3L6NA 4TZBA 1VJNA 2DKFA 5FQAA 1K07A 2BG8B 3ZNBA 4UWRB 4EY2A 5A0VA 4EFZA 5HIOA 4AWYB 4JO0A 4C1GA 5IQKA 3AF6A 4EYFA 4DILA 4J5FA 4RBSA 4Z7RA 4UWOB 3F9OA 5B3RA 3IDZA 4ZNBA 1X8HA 4NQ2A 2WHGA 2WYMC 1YCHA 1DXKA 5ACTA 2Q42A 4UA4A 4D1UA 1WUPA 3A4YA 1HLKA 4HL1A 1WUOA 5DPXA 2BFZA 4YSLA 4LE6A 3IE0A 5KIKA 3SPUA 2FK6A 2Q9UA 4BP0A 4GYUA 4Z5ZA 1QH3A 5EVKA 1WRAA 2BG7A 1YCFA 2R2DA 2DOOA 2NXAA 3SRXA 5ACSA 4Z60A 5ACPA 1QH5A 4FSBA 4Z67A 5LCFA 3AF5A 1BMCA 4YSBA 3ZQ4A 2YZ3A 4D02A 3IEMA 3VQZA 3DHAA 2WRSA 4FEKA 3SD9A 1P9EA 4F6ZA 4C1DA 5LSCA 1XM8A 5LCHA 5HIQA 2BMIA 4TZFA 5LM6A 4ZEJA 1M2XA 4TYFA 1ZKPA 1JT1A 3BK2A 5K4MA 1XTOA 1X8GA 5ACXA 3IE1A 1MQOA 5KILA 3SFPA 5FQCA 2OHHA 5EV6A 3G1PA 2VW8A 3IOFA 2YNTB 4EXYA 2GFJA 2GKLA 3AJ3A 3PG4A 1DDKA 3JXPA 2M5DA 2FU9A 5HISA 2BTNA 3TP9A 3RKJA 3IE2A 4HKYA 4D1WA 1SMLA 2ZWRA 4UBQA 3S0ZA 4UAMA 3IEKA 3PY6A 4AD9A 4YSKA 2YNVB 5ACVA 1Y44A 2FHXB 2BC2A 5EH9A 4C1HA 4RM5A 2XF4A 2Y8AA 5EHTA 1ZNBA 3SBLA 4TZ9A 2Y8BA 4ZO3A 4NQ4A 3X2ZA 1BC2A 3ESHA 2YNUA 1BVTA 4C1EA 2BG8A 4XWTA 3H3EA 4CHLA 2GFKA 3ZR9A 4UWPB 2BGAA 3T9MA 4V0HA 5AYAA 5AXOA 4HL2A 3RKKA 3FAIA 2BR6A 4NQ6A 4WD6A 2QDSA 4P62A 2OHJA 2Q0IA 3I0VA 2AZ4A 4ZO2A 4PVOA 4NQ5A 2GMNA 3BV6A 1DD6A 4C1FA 3I14A 4EXSA 5HH6A 2P1EA 4U4LA 2GCUA 4RL0A 4FR7A 1E5DA 3WXCA 4XWWA 3ADRA 4D1TA 1L9YA 5ACQA 2QINA 5AEBA 1YCGA 3BK1A 5B15A 4XUKA 2FU6A 2Y87A 5EVBA 1WW1A 5B1UA 4J5HA 3IELA 3KNRA 4KEQA 2NZFA 2CBNA 4RAMA 1JJTA 4Z6XA 3VPEA 4B87A 2H6AA 3SW3A 1JJEA 3IOGA 1A8TA 1KO2A 2Q0JA 4D1VA 4O98A 2BFZB 1VGNA 4DIKA 3DHBA 4C09A 1A7TA 5ACWA 3X2YA 5LCAA 5FQBA 4AX0B 2M5CA 2P18A 3DH8A 5EVDA 5K0WA 1ZTCA 2YNWA 2HB9A 4TYTA 2QEDA 4TZEA 3KNSA 2BFLA 5LS3A 2BG2A 4AX1B 2QJSA 3I13A 2UYXA 3RPCA 3PY5A 3BC2A 2WYMA 4EYLA 2OHIA 5EW0A 4C1CA 5LLDA 4H0DA 3QH8A 3ZWFA 2E7YA 2ZZIA 2YNTA 5HIPA 2FU8A 4KEPA 1KR3A 2XR1A 4GYQA 1X8IA 3T3OA 3KL7A 2YCBA 3I11A 5K4NA 3Q6VA 3T3NA 2BFKA 5LE1A 3I15A 2AIOA 5AHOA 2NYPA 2YNVA 2P97A 4BZ3A 4GCWA 2FHXA 4UWSB 4RAWA 5AHRA 4F6HA 3X30A 5EWAA 4AWZA 5HH4A 2A7MA 5EV8A 2NZEA 3R2UA 5A0TA 5AXRA 1VMEA 2I7TA 5A87A 5K4KA 2BG6A 2I7VA 5ACRA 3MD7A 4EYBA 2WYLA 3FCZA 2QDTA 4Z5YA 3X2XA 5HH5A 2BIBA 4PVTA 2ZO4A 5A5ZA 2FU7A 2ZNBA 3LVZA 2I7XA 5LMCA 2FM6A 5ACUA 2P4ZA 3DHCA 1KO3A 4RL2A
chains in the Genus database with same CATH superfamily
3P2UA 3L6NA 4TZBA 1VJNA 2DKFA 5FQAA 1K07A 2BG8B 3ZNBA 4UWRB 4EY2A 5A0VA 4EFZA 5HIOA 5A23A 4AWYB 4JO0A 4C1GA 5IQKA 3AF6A 4EYFA 4DILA 4J5FA 4RBSA 4Z7RA 4UWOB 3F9OA 5B3RA 3IDZA 4ZNBA 1X8HA 4NQ2A 2WHGA 2WYMC 1YCHA 5AIJA 1DXKA 5ACTA 2Q42A 4UA4A 4D1UA 1WUPA 3A4YA 1HLKA 4HL1A 1WUOA 5DPXA 2BFZA 4YSLA 4LE6A 3IE0A 5KIKA 3SPUA 2FK6A 2Q9UA 4BP0A 4GYUA 4Z5ZA 1QH3A 5EVKA 1WRAA 2BG7A 1YCFA 2R2DA 2DOOA 2NXAA 3SRXA 5ACSA 4Z60A 5ACPA 1QH5A 4FSBA 4Z67A 5LCFA 3AF5A 1BMCA 4YSBA 3ZQ4A 2YZ3A 4D02A 3IEMA 3VQZA 3DHAA 2WRSA 4FEKA 3SD9A 1P9EA 4F6ZA 4C1DA 5LSCA 1XM8A 5LCHA 5HIQA 2BMIA 4TZFA 5LM6A 4ZEJA 1M2XA 4TYFA 4AXHA 1ZKPA 1JT1A 3BK2A 5K4MA 1XTOA 1X8GA 5ACXA 3IE1A 1MQOA 5KILA 3SFPA 5FQCA 2OHHA 5EV6A 3G1PA 2VW8A 3IOFA 2CFUA 2YNTB 4EXYA 2GFJA 4NURA 2GKLA 3AJ3A 3PG4A 1DDKA 3JXPA 2M5DA 2FU9A 5HISA 2BTNA 3TP9A 3RKJA 3IE2A 4HKYA 4D1WA 1SMLA 2ZWRA 4UBQA 3S0ZA 4UAMA 3IEKA 3PY6A 4AD9A 4YSKA 2YNVB 5ACVA 1Y44A 2FHXB 2BC2A 5EH9A 4C1HA 4RM5A 2XF4A 2Y8AA 5EHTA 1ZNBA 3SBLA 4TZ9A 2Y8BA 4ZO3A 4NQ4A 3X2ZA 1BC2A 3ESHA 2YNUA 5AJLA 1BVTA 4C1EA 2BG8A 4XWTA 3H3EA 4CHLA 2GFKA 4AV7A 3ZR9A 4UWPB 2BGAA 3T9MA 4V0HA 5AYAA 5AXOA 4HL2A 3RKKA 3FAIA 2BR6A 4NQ6A 4WD6A 2QDSA 4P62A 2OHJA 2Q0IA 3I0VA 2AZ4A 4ZO2A 4PVOA 4NQ5A 2GMNA 3BV6A 1DD6A 4C1FA 3I14A 4EXSA 5HH6A 2P1EA 4U4LA 2GCUA 4RL0A 4FR7A 1E5DA 3WXCA 4XWWA 3ADRA 2CFZA 4D1TA 1L9YA 5ACQA 2QINA 5AEBA 1YCGA 3BK1A 5B15A 4XUKA 2FU6A 2Y87A 5EVBA 2CG2A 1WW1A 5B1UA 4J5HA 3IELA 3KNRA 4KEQA 2NZFA 2CBNA 4RAMA 1JJTA 4Z6XA 3VPEA 4B87A 2H6AA 3SW3A 1JJEA 3IOGA 1A8TA 1KO2A 2Q0JA 4D1VA 4O98A 2BFZB 1VGNA 4DIKA 3DHBA 4C09A 1A7TA 5ACWA 3X2YA 5LCAA 5FQBA 4AX0B 2M5CA 2P18A 3DH8A 5EVDA 5K0WA 1ZTCA 2YNWA 4PDXA 2HB9A 4TYTA 2QEDA 4TZEA 3KNSA 2BFLA 5LS3A 2BG2A 4AX1B 2QJSA 2CG3A 3I13A 2UYXA 3RPCA 3PY5A 3BC2A 2WYMA 4EYLA 2OHIA 5EW0A 4C1CA 5LLDA 4H0DA 3QH8A 3ZWFA 2E7YA 2ZZIA 2YNTA 5HIPA 2FU8A 4KEPA 1KR3A 2XR1A 4GYQA 1X8IA 3T3OA 3KL7A 2YCBA 3I11A 5K4NA 3Q6VA 3T3NA 2BFKA 5LE1A 3I15A 2AIOA 5AHOA 2NYPA 2YNVA 2P97A 2YHEA 4BZ3A 4GCWA 2FHXA 4UWSB 4RAWA 5AHRA 4F6HA 3X30A 5EWAA 4AWZA 5HH4A 2A7MA 5EV8A 2NZEA 3R2UA 5A0TA 5AXRA 1VMEA 2I7TA 5A87A 5K4KA 2BG6A 2I7VA 5ACRA 3MD7A 4EYBA 2WYLA 3FCZA 2QDTA 4Z5YA 3X2XA 5HH5A 2BIBA 4PVTA 2ZO4A 5A5ZA 2FU7A 2ZNBA 3LVZA 2I7XA 5LMCA 2FM6A 5ACUA 2P4ZA 3DHCA 1KO3A 4RL2A
chains in the Genus database with same CATH topology
3P2UA 3L6NA 4TZBA 1VJNA 2DKFA 5FQAA 1K07A 2BG8B 3ZNBA 4UWRB 4EY2A 5A0VA 4EFZA 5HIOA 4AWYB 4JO0A 4C1GA 5IQKA 3AF6A 4EYFA 4DILA 4J5FA 4RBSA 4Z7RA 4UWOB 3F9OA 5B3RA 3IDZA 4ZNBA 1X8HA 4NQ2A 2WHGA 2WYMC 1YCHA 1DXKA 5ACTA 2Q42A 4UA4A 4D1UA 1WUPA 3A4YA 1HLKA 4HL1A 1WUOA 5DPXA 2BFZA 4YSLA 4LE6A 3IE0A 5KIKA 3SPUA 2FK6A 2Q9UA 4BP0A 4GYUA 4Z5ZA 1QH3A 5EVKA 1WRAA 2BG7A 1YCFA 2R2DA 2DOOA 2NXAA 3SRXA 5ACSA 4Z60A 5ACPA 1QH5A 4FSBA 4Z67A 5LCFA 3AF5A 1BMCA 4YSBA 3ZQ4A 2YZ3A 4D02A 3IEMA 3VQZA 3DHAA 2WRSA 4FEKA 3SD9A 1P9EA 4F6ZA 4C1DA 5LSCA 1XM8A 5LCHA 5HIQA 2BMIA 4TZFA 5LM6A 4ZEJA 1M2XA 4TYFA 1ZKPA 1JT1A 3BK2A 5K4MA 1XTOA 1X8GA 5ACXA 3IE1A 1MQOA 5KILA 3SFPA 5FQCA 2OHHA 5EV6A 3G1PA 2VW8A 3IOFA 2YNTB 4EXYA 2GFJA 2GKLA 3AJ3A 3PG4A 1DDKA 3JXPA 2M5DA 2FU9A 5HISA 2BTNA 3TP9A 3RKJA 3IE2A 4HKYA 4D1WA 1SMLA 2ZWRA 4UBQA 3S0ZA 4UAMA 3IEKA 3PY6A 4AD9A 4YSKA 2YNVB 5ACVA 1Y44A 2FHXB 2BC2A 5EH9A 4C1HA 4RM5A 2XF4A 2Y8AA 5EHTA 1ZNBA 3SBLA 4TZ9A 2Y8BA 4ZO3A 4NQ4A 3X2ZA 1BC2A 3ESHA 2YNUA 1BVTA 4C1EA 2BG8A 4XWTA 3H3EA 4CHLA 2GFKA 3ZR9A 4UWPB 2BGAA 3T9MA 4V0HA 5AYAA 5AXOA 4HL2A 3RKKA 3FAIA 2BR6A 4NQ6A 4WD6A 2QDSA 4P62A 2OHJA 2Q0IA 3I0VA 2AZ4A 4ZO2A 4PVOA 4NQ5A 2GMNA 3BV6A 1DD6A 4C1FA 3I14A 4EXSA 5HH6A 2P1EA 4U4LA 2GCUA 4RL0A 4FR7A 1E5DA 3WXCA 4XWWA 3ADRA 4D1TA 1L9YA 5ACQA 2QINA 5AEBA 1YCGA 3BK1A 5B15A 4XUKA 2FU6A 2Y87A 5EVBA 1WW1A 5B1UA 4J5HA 3IELA 3KNRA 4KEQA 2NZFA 2CBNA 4RAMA 1JJTA 4Z6XA 3VPEA 4B87A 2H6AA 3SW3A 1JJEA 3IOGA 1A8TA 1KO2A 2Q0JA 4D1VA 4O98A 2BFZB 1VGNA 4DIKA 3DHBA 4C09A 1A7TA 5ACWA 3X2YA 5LCAA 5FQBA 4AX0B 2M5CA 2P18A 3DH8A 5EVDA 5K0WA 1ZTCA 2YNWA 2HB9A 4TYTA 2QEDA 4TZEA 3KNSA 2BFLA 5LS3A 2BG2A 4AX1B 2QJSA 3I13A 2UYXA 3RPCA 3PY5A 3BC2A 2WYMA 4EYLA 2OHIA 5EW0A 4C1CA 5LLDA 4H0DA 3QH8A 3ZWFA 2E7YA 2ZZIA 2YNTA 5HIPA 2FU8A 4KEPA 1KR3A 2XR1A 4GYQA 1X8IA 3T3OA 3KL7A 2YCBA 3I11A 5K4NA 3Q6VA 3T3NA 2BFKA 5LE1A 3I15A 2AIOA 5AHOA 2NYPA 2YNVA 2P97A 4BZ3A 4GCWA 2FHXA 4UWSB 4RAWA 5AHRA 4F6HA 3X30A 5EWAA 4AWZA 5HH4A 2A7MA 5EV8A 2NZEA 3R2UA 5A0TA 5AXRA 1VMEA 2I7TA 5A87A 5K4KA 2BG6A 2I7VA 5ACRA 3MD7A 4EYBA 2WYLA 3FCZA 2QDTA 4Z5YA 3X2XA 5HH5A 2BIBA 4PVTA 2ZO4A 5A5ZA 2FU7A 2ZNBA 3LVZA 2I7XA 5LMCA 2FM6A 5ACUA 2P4ZA 3DHCA 1KO3A 4RL2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3P2U A;  3L6N A;  4TZB A;  1VJN A;  2DKF A;  5FQA A;  1K07 A;  2BG8 B;  3ZNB A;  4UWR B;  4EY2 A;  5A0V A;  4EFZ A;  5HIO A;  4AWY B;  4JO0 A;  4C1G A;  5IQK A;  3AF6 A;  4EYF A;  4DIL A;  4J5F A;  4RBS A;  4Z7R A;  4UWO B;  3F9O A;  5B3R A;  3IDZ A;  4ZNB A;  1X8H A;  4NQ2 A;  2WHG A;  2WYM C;  1YCH A;  1DXK A;  5ACT A;  2Q42 A;  4UA4 A;  4D1U A;  1WUP A;  3A4Y A;  1HLK A;  4HL1 A;  1WUO A;  5DPX A;  2BFZ A;  4YSL A;  4LE6 A;  3IE0 A;  5KIK A;  3SPU A;  2FK6 A;  2Q9U A;  4BP0 A;  4GYU A;  4Z5Z A;  1QH3 A;  5EVK A;  1WRA A;  2BG7 A;  1YCF A;  2R2D A;  2DOO A;  2NXA A;  3SRX A;  5ACS A;  4Z60 A;  5ACP A;  1QH5 A;  4FSB A;  4Z67 A;  5LCF A;  3AF5 A;  1BMC A;  4YSB A;  3ZQ4 A;  2YZ3 A;  4D02 A;  3IEM A;  3VQZ A;  3DHA A;  2WRS A;  4FEK A;  3SD9 A;  1P9E A;  4F6Z A;  4C1D A;  5LSC A;  1XM8 A;  5LCH A;  5HIQ A;  2BMI A;  4TZF A;  5LM6 A;  4ZEJ A;  1M2X A;  4TYF A;  1ZKP A;  1JT1 A;  3BK2 A;  5K4M A;  1XTO A;  1X8G A;  5ACX A;  3IE1 A;  1MQO A;  5KIL A;  3SFP A;  5FQC A;  2OHH A;  5EV6 A;  3G1P A;  2VW8 A;  3IOF A;  2YNT B;  4EXY A;  2GFJ A;  2GKL A;  3AJ3 A;  3PG4 A;  1DDK A;  3JXP A;  2M5D A;  2FU9 A;  5HIS A;  2BTN A;  3TP9 A;  3RKJ A;  3IE2 A;  4HKY A;  4D1W A;  1SML A;  2ZWR A;  4UBQ A;  3S0Z A;  4UAM A;  3IEK A;  3PY6 A;  4AD9 A;  4YSK A;  2YNV B;  5ACV A;  1Y44 A;  2FHX B;  2BC2 A;  5EH9 A;  4C1H A;  4RM5 A;  2XF4 A;  2Y8A A;  5EHT A;  1ZNB A;  3SBL A;  4TZ9 A;  2Y8B A;  4ZO3 A;  4NQ4 A;  3X2Z A;  1BC2 A;  3ESH A;  2YNU A;  1BVT A;  4C1E A;  2BG8 A;  4XWT A;  3H3E A;  4CHL A;  2GFK A;  3ZR9 A;  4UWP B;  2BGA A;  3T9M A;  4V0H A;  5AYA A;  5AXO A;  4HL2 A;  3RKK A;  3FAI A;  2BR6 A;  4NQ6 A;  4WD6 A;  2QDS A;  4P62 A;  2OHJ A;  2Q0I A;  3I0V A;  2AZ4 A;  4ZO2 A;  4PVO A;  4NQ5 A;  2GMN A;  3BV6 A;  1DD6 A;  4C1F A;  3I14 A;  4EXS A;  5HH6 A;  2P1E A;  4U4L A;  2GCU A;  4RL0 A;  4FR7 A;  1E5D A;  3WXC A;  4XWW A;  3ADR A;  4D1T A;  1L9Y A;  5ACQ A;  2QIN A;  5AEB A;  1YCG A;  3BK1 A;  5B15 A;  4XUK A;  2FU6 A;  2Y87 A;  5EVB A;  1WW1 A;  5B1U A;  4J5H A;  3IEL A;  3KNR A;  4KEQ A;  2NZF A;  2CBN A;  4RAM A;  1JJT A;  4Z6X A;  3VPE A;  4B87 A;  2H6A A;  3SW3 A;  1JJE A;  3IOG A;  1A8T A;  1KO2 A;  2Q0J A;  4D1V A;  4O98 A;  2BFZ B;  1VGN A;  4DIK A;  3DHB A;  4C09 A;  1A7T A;  5ACW A;  3X2Y A;  5LCA A;  5FQB A;  4AX0 B;  2M5C A;  2P18 A;  3DH8 A;  5EVD A;  5K0W A;  1ZTC A;  2YNW A;  2HB9 A;  4TYT A;  2QED A;  4TZE A;  3KNS A;  2BFL A;  5LS3 A;  2BG2 A;  4AX1 B;  2QJS A;  3I13 A;  2UYX A;  3RPC A;  3PY5 A;  3BC2 A;  2WYM A;  4EYL A;  2OHI A;  5EW0 A;  4C1C A;  5LLD A;  4H0D A;  3QH8 A;  3ZWF A;  2E7Y A;  2ZZI A;  2YNT A;  5HIP A;  2FU8 A;  4KEP A;  1KR3 A;  2XR1 A;  4GYQ A;  1X8I A;  3T3O A;  3KL7 A;  2YCB A;  3I11 A;  5K4N A;  3Q6V A;  3T3N A;  2BFK A;  5LE1 A;  3I15 A;  2AIO A;  5AHO A;  2NYP A;  2YNV A;  2P97 A;  4BZ3 A;  4GCW A;  2FHX A;  4UWS B;  4RAW A;  5AHR A;  4F6H A;  3X30 A;  5EWA A;  4AWZ A;  5HH4 A;  2A7M A;  5EV8 A;  2NZE A;  3R2U A;  5A0T A;  5AXR A;  1VME A;  2I7T A;  5A87 A;  5K4K A;  2BG6 A;  2I7V A;  5ACR A;  3MD7 A;  4EYB A;  2WYL A;  3FCZ A;  2QDT A;  4Z5Y A;  3X2X A;  5HH5 A;  2BIB A;  4PVT A;  2ZO4 A;  5A5Z A;  2FU7 A;  2ZNB A;  3LVZ A;  2I7X A;  5LMC A;  2FM6 A;  5ACU A;  2P4Z A;  3DHC A;  1KO3 A;  4RL2 A; 
#chains in the Genus database with same CATH topology
 3P2U A;  3L6N A;  4TZB A;  1VJN A;  2DKF A;  5FQA A;  1K07 A;  2BG8 B;  3ZNB A;  4UWR B;  4EY2 A;  5A0V A;  4EFZ A;  5HIO A;  5A23 A;  4AWY B;  4JO0 A;  4C1G A;  5IQK A;  3AF6 A;  4EYF A;  4DIL A;  4J5F A;  4RBS A;  4Z7R A;  4UWO B;  3F9O A;  5B3R A;  3IDZ A;  4ZNB A;  1X8H A;  4NQ2 A;  2WHG A;  2WYM C;  1YCH A;  5AIJ A;  1DXK A;  5ACT A;  2Q42 A;  4UA4 A;  4D1U A;  1WUP A;  3A4Y A;  1HLK A;  4HL1 A;  1WUO A;  5DPX A;  2BFZ A;  4YSL A;  4LE6 A;  3IE0 A;  5KIK A;  3SPU A;  2FK6 A;  2Q9U A;  4BP0 A;  4GYU A;  4Z5Z A;  1QH3 A;  5EVK A;  1WRA A;  2BG7 A;  1YCF A;  2R2D A;  2DOO A;  2NXA A;  3SRX A;  5ACS A;  4Z60 A;  5ACP A;  1QH5 A;  4FSB A;  4Z67 A;  5LCF A;  3AF5 A;  1BMC A;  4YSB A;  3ZQ4 A;  2YZ3 A;  4D02 A;  3IEM A;  3VQZ A;  3DHA A;  2WRS A;  4FEK A;  3SD9 A;  1P9E A;  4F6Z A;  4C1D A;  5LSC A;  1XM8 A;  5LCH A;  5HIQ A;  2BMI A;  4TZF A;  5LM6 A;  4ZEJ A;  1M2X A;  4TYF A;  4AXH A;  1ZKP A;  1JT1 A;  3BK2 A;  5K4M A;  1XTO A;  1X8G A;  5ACX A;  3IE1 A;  1MQO A;  5KIL A;  3SFP A;  5FQC A;  2OHH A;  5EV6 A;  3G1P A;  2VW8 A;  3IOF A;  2CFU A;  2YNT B;  4EXY A;  2GFJ A;  4NUR A;  2GKL A;  3AJ3 A;  3PG4 A;  1DDK A;  3JXP A;  2M5D A;  2FU9 A;  5HIS A;  2BTN A;  3TP9 A;  3RKJ A;  3IE2 A;  4HKY A;  4D1W A;  1SML A;  2ZWR A;  4UBQ A;  3S0Z A;  4UAM A;  3IEK A;  3PY6 A;  4AD9 A;  4YSK A;  2YNV B;  5ACV A;  1Y44 A;  2FHX B;  2BC2 A;  5EH9 A;  4C1H A;  4RM5 A;  2XF4 A;  2Y8A A;  5EHT A;  1ZNB A;  3SBL A;  4TZ9 A;  2Y8B A;  4ZO3 A;  4NQ4 A;  3X2Z A;  1BC2 A;  3ESH A;  2YNU A;  5AJL A;  1BVT A;  4C1E A;  2BG8 A;  4XWT A;  3H3E A;  4CHL A;  2GFK A;  4AV7 A;  3ZR9 A;  4UWP B;  2BGA A;  3T9M A;  4V0H A;  5AYA A;  5AXO A;  4HL2 A;  3RKK A;  3FAI A;  2BR6 A;  4NQ6 A;  4WD6 A;  2QDS A;  4P62 A;  2OHJ A;  2Q0I A;  3I0V A;  2AZ4 A;  4ZO2 A;  4PVO A;  4NQ5 A;  2GMN A;  3BV6 A;  1DD6 A;  4C1F A;  3I14 A;  4EXS A;  5HH6 A;  2P1E A;  4U4L A;  2GCU A;  4RL0 A;  4FR7 A;  1E5D A;  3WXC A;  4XWW A;  3ADR A;  2CFZ A;  4D1T A;  1L9Y A;  5ACQ A;  2QIN A;  5AEB A;  1YCG A;  3BK1 A;  5B15 A;  4XUK A;  2FU6 A;  2Y87 A;  5EVB A;  2CG2 A;  1WW1 A;  5B1U A;  4J5H A;  3IEL A;  3KNR A;  4KEQ A;  2NZF A;  2CBN A;  4RAM A;  1JJT A;  4Z6X A;  3VPE A;  4B87 A;  2H6A A;  3SW3 A;  1JJE A;  3IOG A;  1A8T A;  1KO2 A;  2Q0J A;  4D1V A;  4O98 A;  2BFZ B;  1VGN A;  4DIK A;  3DHB A;  4C09 A;  1A7T A;  5ACW A;  3X2Y A;  5LCA A;  5FQB A;  4AX0 B;  2M5C A;  2P18 A;  3DH8 A;  5EVD A;  5K0W A;  1ZTC A;  2YNW A;  4PDX A;  2HB9 A;  4TYT A;  2QED A;  4TZE A;  3KNS A;  2BFL A;  5LS3 A;  2BG2 A;  4AX1 B;  2QJS A;  2CG3 A;  3I13 A;  2UYX A;  3RPC A;  3PY5 A;  3BC2 A;  2WYM A;  4EYL A;  2OHI A;  5EW0 A;  4C1C A;  5LLD A;  4H0D A;  3QH8 A;  3ZWF A;  2E7Y A;  2ZZI A;  2YNT A;  5HIP A;  2FU8 A;  4KEP A;  1KR3 A;  2XR1 A;  4GYQ A;  1X8I A;  3T3O A;  3KL7 A;  2YCB A;  3I11 A;  5K4N A;  3Q6V A;  3T3N A;  2BFK A;  5LE1 A;  3I15 A;  2AIO A;  5AHO A;  2NYP A;  2YNV A;  2P97 A;  2YHE A;  4BZ3 A;  4GCW A;  2FHX A;  4UWS B;  4RAW A;  5AHR A;  4F6H A;  3X30 A;  5EWA A;  4AWZ A;  5HH4 A;  2A7M A;  5EV8 A;  2NZE A;  3R2U A;  5A0T A;  5AXR A;  1VME A;  2I7T A;  5A87 A;  5K4K A;  2BG6 A;  2I7V A;  5ACR A;  3MD7 A;  4EYB A;  2WYL A;  3FCZ A;  2QDT A;  4Z5Y A;  3X2X A;  5HH5 A;  2BIB A;  4PVT A;  2ZO4 A;  5A5Z A;  2FU7 A;  2ZNB A;  3LVZ A;  2I7X A;  5LMC A;  2FM6 A;  5ACU A;  2P4Z A;  3DHC A;  1KO3 A;  4RL2 A; 
#chains in the Genus database with same CATH homology
 3P2U A;  3L6N A;  4TZB A;  1VJN A;  2DKF A;  5FQA A;  1K07 A;  2BG8 B;  3ZNB A;  4UWR B;  4EY2 A;  5A0V A;  4EFZ A;  5HIO A;  4AWY B;  4JO0 A;  4C1G A;  5IQK A;  3AF6 A;  4EYF A;  4DIL A;  4J5F A;  4RBS A;  4Z7R A;  4UWO B;  3F9O A;  5B3R A;  3IDZ A;  4ZNB A;  1X8H A;  4NQ2 A;  2WHG A;  2WYM C;  1YCH A;  1DXK A;  5ACT A;  2Q42 A;  4UA4 A;  4D1U A;  1WUP A;  3A4Y A;  1HLK A;  4HL1 A;  1WUO A;  5DPX A;  2BFZ A;  4YSL A;  4LE6 A;  3IE0 A;  5KIK A;  3SPU A;  2FK6 A;  2Q9U A;  4BP0 A;  4GYU A;  4Z5Z A;  1QH3 A;  5EVK A;  1WRA A;  2BG7 A;  1YCF A;  2R2D A;  2DOO A;  2NXA A;  3SRX A;  5ACS A;  4Z60 A;  5ACP A;  1QH5 A;  4FSB A;  4Z67 A;  5LCF A;  3AF5 A;  1BMC A;  4YSB A;  3ZQ4 A;  2YZ3 A;  4D02 A;  3IEM A;  3VQZ A;  3DHA A;  2WRS A;  4FEK A;  3SD9 A;  1P9E A;  4F6Z A;  4C1D A;  5LSC A;  1XM8 A;  5LCH A;  5HIQ A;  2BMI A;  4TZF A;  5LM6 A;  4ZEJ A;  1M2X A;  4TYF A;  1ZKP A;  1JT1 A;  3BK2 A;  5K4M A;  1XTO A;  1X8G A;  5ACX A;  3IE1 A;  1MQO A;  5KIL A;  3SFP A;  5FQC A;  2OHH A;  5EV6 A;  3G1P A;  2VW8 A;  3IOF A;  2YNT B;  4EXY A;  2GFJ A;  2GKL A;  3AJ3 A;  3PG4 A;  1DDK A;  3JXP A;  2M5D A;  2FU9 A;  5HIS A;  2BTN A;  3TP9 A;  3RKJ A;  3IE2 A;  4HKY A;  4D1W A;  1SML A;  2ZWR A;  4UBQ A;  3S0Z A;  4UAM A;  3IEK A;  3PY6 A;  4AD9 A;  4YSK A;  2YNV B;  5ACV A;  1Y44 A;  2FHX B;  2BC2 A;  5EH9 A;  4C1H A;  4RM5 A;  2XF4 A;  2Y8A A;  5EHT A;  1ZNB A;  3SBL A;  4TZ9 A;  2Y8B A;  4ZO3 A;  4NQ4 A;  3X2Z A;  1BC2 A;  3ESH A;  2YNU A;  1BVT A;  4C1E A;  2BG8 A;  4XWT A;  3H3E A;  4CHL A;  2GFK A;  3ZR9 A;  4UWP B;  2BGA A;  3T9M A;  4V0H A;  5AYA A;  5AXO A;  4HL2 A;  3RKK A;  3FAI A;  2BR6 A;  4NQ6 A;  4WD6 A;  2QDS A;  4P62 A;  2OHJ A;  2Q0I A;  3I0V A;  2AZ4 A;  4ZO2 A;  4PVO A;  4NQ5 A;  2GMN A;  3BV6 A;  1DD6 A;  4C1F A;  3I14 A;  4EXS A;  5HH6 A;  2P1E A;  4U4L A;  2GCU A;  4RL0 A;  4FR7 A;  1E5D A;  3WXC A;  4XWW A;  3ADR A;  4D1T A;  1L9Y A;  5ACQ A;  2QIN A;  5AEB A;  1YCG A;  3BK1 A;  5B15 A;  4XUK A;  2FU6 A;  2Y87 A;  5EVB A;  1WW1 A;  5B1U A;  4J5H A;  3IEL A;  3KNR A;  4KEQ A;  2NZF A;  2CBN A;  4RAM A;  1JJT A;  4Z6X A;  3VPE A;  4B87 A;  2H6A A;  3SW3 A;  1JJE A;  3IOG A;  1A8T A;  1KO2 A;  2Q0J A;  4D1V A;  4O98 A;  2BFZ B;  1VGN A;  4DIK A;  3DHB A;  4C09 A;  1A7T A;  5ACW A;  3X2Y A;  5LCA A;  5FQB A;  4AX0 B;  2M5C A;  2P18 A;  3DH8 A;  5EVD A;  5K0W A;  1ZTC A;  2YNW A;  2HB9 A;  4TYT A;  2QED A;  4TZE A;  3KNS A;  2BFL A;  5LS3 A;  2BG2 A;  4AX1 B;  2QJS A;  3I13 A;  2UYX A;  3RPC A;  3PY5 A;  3BC2 A;  2WYM A;  4EYL A;  2OHI A;  5EW0 A;  4C1C A;  5LLD A;  4H0D A;  3QH8 A;  3ZWF A;  2E7Y A;  2ZZI A;  2YNT A;  5HIP A;  2FU8 A;  4KEP A;  1KR3 A;  2XR1 A;  4GYQ A;  1X8I A;  3T3O A;  3KL7 A;  2YCB A;  3I11 A;  5K4N A;  3Q6V A;  3T3N A;  2BFK A;  5LE1 A;  3I15 A;  2AIO A;  5AHO A;  2NYP A;  2YNV A;  2P97 A;  4BZ3 A;  4GCW A;  2FHX A;  4UWS B;  4RAW A;  5AHR A;  4F6H A;  3X30 A;  5EWA A;  4AWZ A;  5HH4 A;  2A7M A;  5EV8 A;  2NZE A;  3R2U A;  5A0T A;  5AXR A;  1VME A;  2I7T A;  5A87 A;  5K4K A;  2BG6 A;  2I7V A;  5ACR A;  3MD7 A;  4EYB A;  2WYL A;  3FCZ A;  2QDT A;  4Z5Y A;  3X2X A;  5HH5 A;  2BIB A;  4PVT A;  2ZO4 A;  5A5Z A;  2FU7 A;  2ZNB A;  3LVZ A;  2I7X A;  5LMC A;  2FM6 A;  5ACU A;  2P4Z A;  3DHC A;  1KO3 A;  4RL2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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