5ACWA

Vim-2-1, discovery of novel inhibitor scaffolds against the metallo- beta-lactamase vim-2 by spr based fragment screening
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
233
structure length
232
Chain Sequence
GEYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNRS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of Novel Inhibitor Scaffolds Against the Metallo-Beta-Lactamase Vim-2 by Spr Based Fragment Screening
pubmed doi rcsb
source organism Pseudomonas aeruginosa
molecule tags Hydrolase
molecule keywords BETA-LACTAMASE
total genus 73
structure length 232
sequence length 233
chains with identical sequence B
ec nomenclature ec 3.5.2.6: Beta-lactamase.
pdb deposition date 2015-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5acwA00
4EFZA 3ZR9A 5EW0A 3IE1A 3IEMA 4YSLA 4ZEJA 4UBQA 3S0ZA 4Z60A 3R2UA 4NQ6A 3IOFA 1VJNA 2I7TA 2BFLA 2QDSA 1A8TA 2WYLA 5HIPA 4D1VA 4D02A 5AXRA 3IOGA 2BMIA 2FHXA 1VMEA 5EV8A 4LE6A 5ACXA 2I7XA 2FU8A 5ACWA 1P9EA 5ACPA 2YZ3A 2Y87A 3X2ZA 1KO2A 3I14A 3T9MA 2GFJA 2BG7A 5B3RA 3T3OA 4RBSA 5HIQA 5AYAA 2FHXB 1YCHA 5EVKA 2BIBA 3FCZA 4H0DA 3WXCA 1ZNBA 4AX0B 1YCFA 2YCBA 4V0HA 1KO3A 2QDTA 3QH8A 4YSBA 4D1UA 2P4ZA 4TZEA 2P97A 1BC2A 1JJEA 5HH4A 2XF4A 2E7YA 2A7MA 3L6NA 4PVOA 5K0WA 1Y44A 2M5DA 1DDKA 4AD9A 2R2DA 5K4MA 3SFPA 4NQ4A 4P62A 4U4LA 3IELA 4BZ3A 3IEKA 4B87A 4Z5ZA 3I15A 4HKYA 2OHJA 2QINA 4XUKA 4ZO3A 1DXKA 1WRAA 3X2YA 2VW8A 5FQCA 3PG4A 5EVBA 2FU6A 3AF5A 2ZNBA 4RM5A 2AZ4A 2GKLA 5ACRA 1JJTA 2DOOA 2WHGA 2BG8B 3H3EA 2BFKA 3RPCA 3ZWFA 3ADRA 5ACTA 1MQOA 2Q0JA 2YNVB 1QH5A 3A4YA 4GYUA 5KILA 3DHAA 2FM6A 5B1UA 5HISA 4EXSA 1K07A 4C1FA 3IE2A 5FQBA 5LLDA 5A87A 4HL1A 2BFZA 4EXYA 4TZ9A 5A0VA 5LE1A 4WD6A 3X30A 4DILA 4F6HA 4J5HA 3SRXA 4RAWA 5B15A 2P1EA 2BG2A 1VGNA 5IQKA 4AWZA 1BMCA 4Z5YA 1WUPA 3P2UA 1SMLA 1BVTA 4ZO2A 2ZO4A 4D1TA 3I13A 4KEQA 2BG8A 2I7VA 5LCFA 1ZTCA 3I0VA 5HIOA 4KEPA 2OHHA 4ZNBA 3JXPA 5AHRA 4UWRB 5AXOA 4DIKA 2XR1A 1X8IA 3KNRA 3RKJA 4UWOB 1KR3A 1HLKA 4EYLA 2WYMC 4XWWA 4BP0A 2YNUA 4HL2A 1YCGA 4C1CA 2UYXA 2AIOA 4C09A 1XM8A 3FAIA 3MD7A 2HB9A 1ZKPA 1WUOA 4GYQA 2Y8BA 5AHOA 2YNWA 2BFZB 4EYFA 3RKKA 3F9OA 2CBNA 2QEDA 4XWTA 1M2XA 2FU9A 2YNVA 3BK1A 2Q0IA 1QH3A 4FR7A 3IE0A 4Z67A 1JT1A 4FSBA 3ZNBA 4EY2A 1E5DA 4EYBA 4RL0A 3BV6A 5EVDA 3I11A 4TYFA 4Z6XA 2BGAA 2Q42A 4RL2A 2ZWRA 3G1PA 3KL7A 3VQZA 2NXAA 5AEBA 5HH5A 4C1HA 2BTNA 2WRSA 3TP9A 4PVTA 4NQ5A 2Y8AA 2WYMA 5EWAA 2DKFA 4UWSB 2YNTB 2Q9UA 4C1GA 2QJSA 5ACSA 4AX1B 4Z7RA 4D1WA 3ESHA 4TZFA 5LM6A 4FEKA 2FK6A 2YNTA 5FQAA 4UAMA 2BR6A 4AWYB 4YSKA 1A7TA 5ACVA 3Q6VA 3AJ3A 4GCWA 3SBLA 2M5CA 1L9YA 5LCAA 2NYPA 5ACQA 3AF6A 4JO0A 3DHBA 4RAMA 1DD6A 5HH6A 2OHIA 5EV6A 5K4KA 3VPEA 2BC2A 3SW3A 3X2XA 3PY5A 3SD9A 3BK2A 1WW1A 4F6ZA 3BC2A 5KIKA 3DHCA 5EH9A 1X8GA 5DPXA 2H6AA 5LS3A 4C1EA 5LMCA 3ZQ4A 3T3NA 3DH8A 5A0TA 3LVZA 5LCHA 1X8HA 1XTOA 5EHTA 4O98A 4J5FA 2P18A 3SPUA 4CHLA 5ACUA 4NQ2A 3KNSA 5A5ZA 5LSCA 4UWPB 3PY6A 4UA4A 2NZFA 4TYTA 3IDZA 5K4NA 2ZZIA 2NZEA 2BG6A 4C1DA 4TZBA 2GFKA 2GMNA 2FU7A 2GCUA
chains in the Genus database with same CATH superfamily
4EFZA 3ZR9A 5EW0A 3IE1A 3IEMA 4YSLA 4ZEJA 4AV7A 4UBQA 3S0ZA 4Z60A 3R2UA 4NQ6A 3IOFA 1VJNA 2I7TA 2BFLA 2QDSA 1A8TA 2WYLA 5HIPA 4D1VA 4D02A 5AXRA 3IOGA 2BMIA 2FHXA 1VMEA 5EV8A 4LE6A 5AJLA 2I7XA 5ACXA 2FU8A 5ACWA 1P9EA 5ACPA 2YZ3A 2Y87A 3X2ZA 1KO2A 3I14A 3T9MA 2GFJA 2BG7A 5B3RA 3T3OA 4RBSA 5HIQA 5AYAA 2FHXB 1YCHA 5EVKA 2BIBA 3FCZA 4H0DA 3WXCA 1ZNBA 4AX0B 1YCFA 2YCBA 4V0HA 1KO3A 2QDTA 3QH8A 4YSBA 4D1UA 2P4ZA 4TZEA 2P97A 1BC2A 1JJEA 5HH4A 2XF4A 2E7YA 2A7MA 3L6NA 4PVOA 5K0WA 1Y44A 2M5DA 1DDKA 4AD9A 2R2DA 5K4MA 3SFPA 4NQ4A 4P62A 4U4LA 3IELA 4BZ3A 3IEKA 4B87A 4Z5ZA 3I15A 4HKYA 2OHJA 2QINA 4XUKA 4ZO3A 1DXKA 2CFUA 1WRAA 3X2YA 2VW8A 5FQCA 3PG4A 5EVBA 2FU6A 3AF5A 2ZNBA 4RM5A 4PDXA 2AZ4A 2GKLA 4NURA 5ACRA 1JJTA 2DOOA 2WHGA 2BG8B 3H3EA 2BFKA 3RPCA 3ZWFA 3ADRA 5ACTA 1MQOA 2Q0JA 2YNVB 1QH5A 3A4YA 4GYUA 5KILA 3DHAA 2FM6A 5B1UA 5HISA 2CG3A 4EXSA 1K07A 4C1FA 2CG2A 3IE2A 5FQBA 5LLDA 5A87A 4HL1A 2BFZA 4EXYA 4TZ9A 5A0VA 5LE1A 4WD6A 3X30A 4DILA 4F6HA 4J5HA 3SRXA 4RAWA 5B15A 2P1EA 2BG2A 1VGNA 5IQKA 4AWZA 1BMCA 4Z5YA 1WUPA 3P2UA 1SMLA 1BVTA 4ZO2A 2ZO4A 4D1TA 3I13A 4KEQA 2BG8A 2I7VA 5LCFA 1ZTCA 3I0VA 5HIOA 4KEPA 2OHHA 4ZNBA 3JXPA 5AHRA 4UWRB 5AXOA 4DIKA 2XR1A 1X8IA 3KNRA 3RKJA 4UWOB 1KR3A 1HLKA 4EYLA 2WYMC 4XWWA 4BP0A 2YNUA 4HL2A 1YCGA 4C1CA 2UYXA 2AIOA 4C09A 1XM8A 4AXHA 3FAIA 3MD7A 2HB9A 1ZKPA 1WUOA 4GYQA 2Y8BA 2CFZA 5AHOA 2YNWA 2BFZB 4EYFA 3RKKA 3F9OA 2CBNA 2QEDA 4XWTA 1M2XA 2FU9A 2YNVA 3BK1A 2Q0IA 1QH3A 4FR7A 3IE0A 4Z67A 1JT1A 4FSBA 3ZNBA 4EY2A 1E5DA 4EYBA 4RL0A 3BV6A 5EVDA 3I11A 4TYFA 4Z6XA 2BGAA 2Q42A 4RL2A 2ZWRA 3G1PA 3KL7A 3VQZA 2NXAA 5AEBA 5HH5A 4C1HA 2BTNA 2WRSA 3TP9A 4PVTA 4NQ5A 2Y8AA 2WYMA 5EWAA 2DKFA 4UWSB 2YNTB 2Q9UA 4C1GA 2QJSA 5ACSA 4AX1B 4Z7RA 4D1WA 3ESHA 4TZFA 5LM6A 4FEKA 2FK6A 2YNTA 5FQAA 4UAMA 5A23A 2BR6A 4AWYB 4YSKA 1A7TA 5ACVA 3Q6VA 3AJ3A 4GCWA 3SBLA 2M5CA 1L9YA 5LCAA 2NYPA 5ACQA 3AF6A 4JO0A 3DHBA 4RAMA 1DD6A 5HH6A 2OHIA 5EV6A 5K4KA 3VPEA 2BC2A 3SW3A 3X2XA 3PY5A 3SD9A 3BK2A 1WW1A 4F6ZA 3BC2A 5KIKA 3DHCA 5EH9A 1X8GA 5DPXA 2H6AA 5LS3A 4C1EA 5LMCA 3ZQ4A 3T3NA 3DH8A 5A0TA 3LVZA 5LCHA 1X8HA 1XTOA 5EHTA 4O98A 4J5FA 2P18A 2YHEA 3SPUA 4CHLA 5ACUA 4NQ2A 3KNSA 5A5ZA 5LSCA 4UWPB 3PY6A 4UA4A 2NZFA 4TYTA 5AIJA 3IDZA 5K4NA 2ZZIA 2NZEA 2BG6A 4C1DA 4TZBA 2GFKA 2GMNA 2FU7A 2GCUA
chains in the Genus database with same CATH topology
4EFZA 3ZR9A 5EW0A 3IE1A 3IEMA 4YSLA 4ZEJA 4UBQA 3S0ZA 4Z60A 3R2UA 4NQ6A 3IOFA 1VJNA 2I7TA 2BFLA 2QDSA 1A8TA 2WYLA 5HIPA 4D1VA 4D02A 5AXRA 3IOGA 2BMIA 2FHXA 1VMEA 5EV8A 4LE6A 5ACXA 2I7XA 2FU8A 5ACWA 1P9EA 5ACPA 2YZ3A 2Y87A 3X2ZA 1KO2A 3I14A 3T9MA 2GFJA 2BG7A 5B3RA 3T3OA 4RBSA 5HIQA 5AYAA 2FHXB 1YCHA 5EVKA 2BIBA 3FCZA 4H0DA 3WXCA 1ZNBA 4AX0B 1YCFA 2YCBA 4V0HA 1KO3A 2QDTA 3QH8A 4YSBA 4D1UA 2P4ZA 4TZEA 2P97A 1BC2A 1JJEA 5HH4A 2XF4A 2E7YA 2A7MA 3L6NA 4PVOA 5K0WA 1Y44A 2M5DA 1DDKA 4AD9A 2R2DA 5K4MA 3SFPA 4NQ4A 4P62A 4U4LA 3IELA 4BZ3A 3IEKA 4B87A 4Z5ZA 3I15A 4HKYA 2OHJA 2QINA 4XUKA 4ZO3A 1DXKA 1WRAA 3X2YA 2VW8A 5FQCA 3PG4A 5EVBA 2FU6A 3AF5A 2ZNBA 4RM5A 2AZ4A 2GKLA 5ACRA 1JJTA 2DOOA 2WHGA 2BG8B 3H3EA 2BFKA 3RPCA 3ZWFA 3ADRA 5ACTA 1MQOA 2Q0JA 2YNVB 1QH5A 3A4YA 4GYUA 5KILA 3DHAA 2FM6A 5B1UA 5HISA 4EXSA 1K07A 4C1FA 3IE2A 5FQBA 5LLDA 5A87A 4HL1A 2BFZA 4EXYA 4TZ9A 5A0VA 5LE1A 4WD6A 3X30A 4DILA 4F6HA 4J5HA 3SRXA 4RAWA 5B15A 2P1EA 2BG2A 1VGNA 5IQKA 4AWZA 1BMCA 4Z5YA 1WUPA 3P2UA 1SMLA 1BVTA 4ZO2A 2ZO4A 4D1TA 3I13A 4KEQA 2BG8A 2I7VA 5LCFA 1ZTCA 3I0VA 5HIOA 4KEPA 2OHHA 4ZNBA 3JXPA 5AHRA 4UWRB 5AXOA 4DIKA 2XR1A 1X8IA 3KNRA 3RKJA 4UWOB 1KR3A 1HLKA 4EYLA 2WYMC 4XWWA 4BP0A 2YNUA 4HL2A 1YCGA 4C1CA 2UYXA 2AIOA 4C09A 1XM8A 3FAIA 3MD7A 2HB9A 1ZKPA 1WUOA 4GYQA 2Y8BA 5AHOA 2YNWA 2BFZB 4EYFA 3RKKA 3F9OA 2CBNA 2QEDA 4XWTA 1M2XA 2FU9A 2YNVA 3BK1A 2Q0IA 1QH3A 4FR7A 3IE0A 4Z67A 1JT1A 4FSBA 3ZNBA 4EY2A 1E5DA 4EYBA 4RL0A 3BV6A 5EVDA 3I11A 4TYFA 4Z6XA 2BGAA 2Q42A 4RL2A 2ZWRA 3G1PA 3KL7A 3VQZA 2NXAA 5AEBA 5HH5A 4C1HA 2BTNA 2WRSA 3TP9A 4PVTA 4NQ5A 2Y8AA 2WYMA 5EWAA 2DKFA 4UWSB 2YNTB 2Q9UA 4C1GA 2QJSA 5ACSA 4AX1B 4Z7RA 4D1WA 3ESHA 4TZFA 5LM6A 4FEKA 2FK6A 2YNTA 5FQAA 4UAMA 2BR6A 4AWYB 4YSKA 1A7TA 5ACVA 3Q6VA 3AJ3A 4GCWA 3SBLA 2M5CA 1L9YA 5LCAA 2NYPA 5ACQA 3AF6A 4JO0A 3DHBA 4RAMA 1DD6A 5HH6A 2OHIA 5EV6A 5K4KA 3VPEA 2BC2A 3SW3A 3X2XA 3PY5A 3SD9A 3BK2A 1WW1A 4F6ZA 3BC2A 5KIKA 3DHCA 5EH9A 1X8GA 5DPXA 2H6AA 5LS3A 4C1EA 5LMCA 3ZQ4A 3T3NA 3DH8A 5A0TA 3LVZA 5LCHA 1X8HA 1XTOA 5EHTA 4O98A 4J5FA 2P18A 3SPUA 4CHLA 5ACUA 4NQ2A 3KNSA 5A5ZA 5LSCA 4UWPB 3PY6A 4UA4A 2NZFA 4TYTA 3IDZA 5K4NA 2ZZIA 2NZEA 2BG6A 4C1DA 4TZBA 2GFKA 2GMNA 2FU7A 2GCUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EFZ A;  3ZR9 A;  5EW0 A;  3IE1 A;  3IEM A;  4YSL A;  4ZEJ A;  4UBQ A;  3S0Z A;  4Z60 A;  3R2U A;  4NQ6 A;  3IOF A;  1VJN A;  2I7T A;  2BFL A;  2QDS A;  1A8T A;  2WYL A;  5HIP A;  4D1V A;  4D02 A;  5AXR A;  3IOG A;  2BMI A;  2FHX A;  1VME A;  5EV8 A;  4LE6 A;  5ACX A;  2I7X A;  2FU8 A;  5ACW A;  1P9E A;  5ACP A;  2YZ3 A;  2Y87 A;  3X2Z A;  1KO2 A;  3I14 A;  3T9M A;  2GFJ A;  2BG7 A;  5B3R A;  3T3O A;  4RBS A;  5HIQ A;  5AYA A;  2FHX B;  1YCH A;  5EVK A;  2BIB A;  3FCZ A;  4H0D A;  3WXC A;  1ZNB A;  4AX0 B;  1YCF A;  2YCB A;  4V0H A;  1KO3 A;  2QDT A;  3QH8 A;  4YSB A;  4D1U A;  2P4Z A;  4TZE A;  2P97 A;  1BC2 A;  1JJE A;  5HH4 A;  2XF4 A;  2E7Y A;  2A7M A;  3L6N A;  4PVO A;  5K0W A;  1Y44 A;  2M5D A;  1DDK A;  4AD9 A;  2R2D A;  5K4M A;  3SFP A;  4NQ4 A;  4P62 A;  4U4L A;  3IEL A;  4BZ3 A;  3IEK A;  4B87 A;  4Z5Z A;  3I15 A;  4HKY A;  2OHJ A;  2QIN A;  4XUK A;  4ZO3 A;  1DXK A;  1WRA A;  3X2Y A;  2VW8 A;  5FQC A;  3PG4 A;  5EVB A;  2FU6 A;  3AF5 A;  2ZNB A;  4RM5 A;  2AZ4 A;  2GKL A;  5ACR A;  1JJT A;  2DOO A;  2WHG A;  2BG8 B;  3H3E A;  2BFK A;  3RPC A;  3ZWF A;  3ADR A;  5ACT A;  1MQO A;  2Q0J A;  2YNV B;  1QH5 A;  3A4Y A;  4GYU A;  5KIL A;  3DHA A;  2FM6 A;  5B1U A;  5HIS A;  4EXS A;  1K07 A;  4C1F A;  3IE2 A;  5FQB A;  5LLD A;  5A87 A;  4HL1 A;  2BFZ A;  4EXY A;  4TZ9 A;  5A0V A;  5LE1 A;  4WD6 A;  3X30 A;  4DIL A;  4F6H A;  4J5H A;  3SRX A;  4RAW A;  5B15 A;  2P1E A;  2BG2 A;  1VGN A;  5IQK A;  4AWZ A;  1BMC A;  4Z5Y A;  1WUP A;  3P2U A;  1SML A;  1BVT A;  4ZO2 A;  2ZO4 A;  4D1T A;  3I13 A;  4KEQ A;  2BG8 A;  2I7V A;  5LCF A;  1ZTC A;  3I0V A;  5HIO A;  4KEP A;  2OHH A;  4ZNB A;  3JXP A;  5AHR A;  4UWR B;  5AXO A;  4DIK A;  2XR1 A;  1X8I A;  3KNR A;  3RKJ A;  4UWO B;  1KR3 A;  1HLK A;  4EYL A;  2WYM C;  4XWW A;  4BP0 A;  2YNU A;  4HL2 A;  1YCG A;  4C1C A;  2UYX A;  2AIO A;  4C09 A;  1XM8 A;  3FAI A;  3MD7 A;  2HB9 A;  1ZKP A;  1WUO A;  4GYQ A;  2Y8B A;  5AHO A;  2YNW A;  2BFZ B;  4EYF A;  3RKK A;  3F9O A;  2CBN A;  2QED A;  4XWT A;  1M2X A;  2FU9 A;  2YNV A;  3BK1 A;  2Q0I A;  1QH3 A;  4FR7 A;  3IE0 A;  4Z67 A;  1JT1 A;  4FSB A;  3ZNB A;  4EY2 A;  1E5D A;  4EYB A;  4RL0 A;  3BV6 A;  5EVD A;  3I11 A;  4TYF A;  4Z6X A;  2BGA A;  2Q42 A;  4RL2 A;  2ZWR A;  3G1P A;  3KL7 A;  3VQZ A;  2NXA A;  5AEB A;  5HH5 A;  4C1H A;  2BTN A;  2WRS A;  3TP9 A;  4PVT A;  4NQ5 A;  2Y8A A;  2WYM A;  5EWA A;  2DKF A;  4UWS B;  2YNT B;  2Q9U A;  4C1G A;  2QJS A;  5ACS A;  4AX1 B;  4Z7R A;  4D1W A;  3ESH A;  4TZF A;  5LM6 A;  4FEK A;  2FK6 A;  2YNT A;  5FQA A;  4UAM A;  2BR6 A;  4AWY B;  4YSK A;  1A7T A;  5ACV A;  3Q6V A;  3AJ3 A;  4GCW A;  3SBL A;  2M5C A;  1L9Y A;  5LCA A;  2NYP A;  5ACQ A;  3AF6 A;  4JO0 A;  3DHB A;  4RAM A;  1DD6 A;  5HH6 A;  2OHI A;  5EV6 A;  5K4K A;  3VPE A;  2BC2 A;  3SW3 A;  3X2X A;  3PY5 A;  3SD9 A;  3BK2 A;  1WW1 A;  4F6Z A;  3BC2 A;  5KIK A;  3DHC A;  5EH9 A;  1X8G A;  5DPX A;  2H6A A;  5LS3 A;  4C1E A;  5LMC A;  3ZQ4 A;  3T3N A;  3DH8 A;  5A0T A;  3LVZ A;  5LCH A;  1X8H A;  1XTO A;  5EHT A;  4O98 A;  4J5F A;  2P18 A;  3SPU A;  4CHL A;  5ACU A;  4NQ2 A;  3KNS A;  5A5Z A;  5LSC A;  4UWP B;  3PY6 A;  4UA4 A;  2NZF A;  4TYT A;  3IDZ A;  5K4N A;  2ZZI A;  2NZE A;  2BG6 A;  4C1D A;  4TZB A;  2GFK A;  2GMN A;  2FU7 A;  2GCU A; 
#chains in the Genus database with same CATH topology
 4EFZ A;  3ZR9 A;  5EW0 A;  3IE1 A;  3IEM A;  4YSL A;  4ZEJ A;  4AV7 A;  4UBQ A;  3S0Z A;  4Z60 A;  3R2U A;  4NQ6 A;  3IOF A;  1VJN A;  2I7T A;  2BFL A;  2QDS A;  1A8T A;  2WYL A;  5HIP A;  4D1V A;  4D02 A;  5AXR A;  3IOG A;  2BMI A;  2FHX A;  1VME A;  5EV8 A;  4LE6 A;  5AJL A;  2I7X A;  5ACX A;  2FU8 A;  5ACW A;  1P9E A;  5ACP A;  2YZ3 A;  2Y87 A;  3X2Z A;  1KO2 A;  3I14 A;  3T9M A;  2GFJ A;  2BG7 A;  5B3R A;  3T3O A;  4RBS A;  5HIQ A;  5AYA A;  2FHX B;  1YCH A;  5EVK A;  2BIB A;  3FCZ A;  4H0D A;  3WXC A;  1ZNB A;  4AX0 B;  1YCF A;  2YCB A;  4V0H A;  1KO3 A;  2QDT A;  3QH8 A;  4YSB A;  4D1U A;  2P4Z A;  4TZE A;  2P97 A;  1BC2 A;  1JJE A;  5HH4 A;  2XF4 A;  2E7Y A;  2A7M A;  3L6N A;  4PVO A;  5K0W A;  1Y44 A;  2M5D A;  1DDK A;  4AD9 A;  2R2D A;  5K4M A;  3SFP A;  4NQ4 A;  4P62 A;  4U4L A;  3IEL A;  4BZ3 A;  3IEK A;  4B87 A;  4Z5Z A;  3I15 A;  4HKY A;  2OHJ A;  2QIN A;  4XUK A;  4ZO3 A;  1DXK A;  2CFU A;  1WRA A;  3X2Y A;  2VW8 A;  5FQC A;  3PG4 A;  5EVB A;  2FU6 A;  3AF5 A;  2ZNB A;  4RM5 A;  4PDX A;  2AZ4 A;  2GKL A;  4NUR A;  5ACR A;  1JJT A;  2DOO A;  2WHG A;  2BG8 B;  3H3E A;  2BFK A;  3RPC A;  3ZWF A;  3ADR A;  5ACT A;  1MQO A;  2Q0J A;  2YNV B;  1QH5 A;  3A4Y A;  4GYU A;  5KIL A;  3DHA A;  2FM6 A;  5B1U A;  5HIS A;  2CG3 A;  4EXS A;  1K07 A;  4C1F A;  2CG2 A;  3IE2 A;  5FQB A;  5LLD A;  5A87 A;  4HL1 A;  2BFZ A;  4EXY A;  4TZ9 A;  5A0V A;  5LE1 A;  4WD6 A;  3X30 A;  4DIL A;  4F6H A;  4J5H A;  3SRX A;  4RAW A;  5B15 A;  2P1E A;  2BG2 A;  1VGN A;  5IQK A;  4AWZ A;  1BMC A;  4Z5Y A;  1WUP A;  3P2U A;  1SML A;  1BVT A;  4ZO2 A;  2ZO4 A;  4D1T A;  3I13 A;  4KEQ A;  2BG8 A;  2I7V A;  5LCF A;  1ZTC A;  3I0V A;  5HIO A;  4KEP A;  2OHH A;  4ZNB A;  3JXP A;  5AHR A;  4UWR B;  5AXO A;  4DIK A;  2XR1 A;  1X8I A;  3KNR A;  3RKJ A;  4UWO B;  1KR3 A;  1HLK A;  4EYL A;  2WYM C;  4XWW A;  4BP0 A;  2YNU A;  4HL2 A;  1YCG A;  4C1C A;  2UYX A;  2AIO A;  4C09 A;  1XM8 A;  4AXH A;  3FAI A;  3MD7 A;  2HB9 A;  1ZKP A;  1WUO A;  4GYQ A;  2Y8B A;  2CFZ A;  5AHO A;  2YNW A;  2BFZ B;  4EYF A;  3RKK A;  3F9O A;  2CBN A;  2QED A;  4XWT A;  1M2X A;  2FU9 A;  2YNV A;  3BK1 A;  2Q0I A;  1QH3 A;  4FR7 A;  3IE0 A;  4Z67 A;  1JT1 A;  4FSB A;  3ZNB A;  4EY2 A;  1E5D A;  4EYB A;  4RL0 A;  3BV6 A;  5EVD A;  3I11 A;  4TYF A;  4Z6X A;  2BGA A;  2Q42 A;  4RL2 A;  2ZWR A;  3G1P A;  3KL7 A;  3VQZ A;  2NXA A;  5AEB A;  5HH5 A;  4C1H A;  2BTN A;  2WRS A;  3TP9 A;  4PVT A;  4NQ5 A;  2Y8A A;  2WYM A;  5EWA A;  2DKF A;  4UWS B;  2YNT B;  2Q9U A;  4C1G A;  2QJS A;  5ACS A;  4AX1 B;  4Z7R A;  4D1W A;  3ESH A;  4TZF A;  5LM6 A;  4FEK A;  2FK6 A;  2YNT A;  5FQA A;  4UAM A;  5A23 A;  2BR6 A;  4AWY B;  4YSK A;  1A7T A;  5ACV A;  3Q6V A;  3AJ3 A;  4GCW A;  3SBL A;  2M5C A;  1L9Y A;  5LCA A;  2NYP A;  5ACQ A;  3AF6 A;  4JO0 A;  3DHB A;  4RAM A;  1DD6 A;  5HH6 A;  2OHI A;  5EV6 A;  5K4K A;  3VPE A;  2BC2 A;  3SW3 A;  3X2X A;  3PY5 A;  3SD9 A;  3BK2 A;  1WW1 A;  4F6Z A;  3BC2 A;  5KIK A;  3DHC A;  5EH9 A;  1X8G A;  5DPX A;  2H6A A;  5LS3 A;  4C1E A;  5LMC A;  3ZQ4 A;  3T3N A;  3DH8 A;  5A0T A;  3LVZ A;  5LCH A;  1X8H A;  1XTO A;  5EHT A;  4O98 A;  4J5F A;  2P18 A;  2YHE A;  3SPU A;  4CHL A;  5ACU A;  4NQ2 A;  3KNS A;  5A5Z A;  5LSC A;  4UWP B;  3PY6 A;  4UA4 A;  2NZF A;  4TYT A;  5AIJ A;  3IDZ A;  5K4N A;  2ZZI A;  2NZE A;  2BG6 A;  4C1D A;  4TZB A;  2GFK A;  2GMN A;  2FU7 A;  2GCU A; 
#chains in the Genus database with same CATH homology
 4EFZ A;  3ZR9 A;  5EW0 A;  3IE1 A;  3IEM A;  4YSL A;  4ZEJ A;  4UBQ A;  3S0Z A;  4Z60 A;  3R2U A;  4NQ6 A;  3IOF A;  1VJN A;  2I7T A;  2BFL A;  2QDS A;  1A8T A;  2WYL A;  5HIP A;  4D1V A;  4D02 A;  5AXR A;  3IOG A;  2BMI A;  2FHX A;  1VME A;  5EV8 A;  4LE6 A;  5ACX A;  2I7X A;  2FU8 A;  5ACW A;  1P9E A;  5ACP A;  2YZ3 A;  2Y87 A;  3X2Z A;  1KO2 A;  3I14 A;  3T9M A;  2GFJ A;  2BG7 A;  5B3R A;  3T3O A;  4RBS A;  5HIQ A;  5AYA A;  2FHX B;  1YCH A;  5EVK A;  2BIB A;  3FCZ A;  4H0D A;  3WXC A;  1ZNB A;  4AX0 B;  1YCF A;  2YCB A;  4V0H A;  1KO3 A;  2QDT A;  3QH8 A;  4YSB A;  4D1U A;  2P4Z A;  4TZE A;  2P97 A;  1BC2 A;  1JJE A;  5HH4 A;  2XF4 A;  2E7Y A;  2A7M A;  3L6N A;  4PVO A;  5K0W A;  1Y44 A;  2M5D A;  1DDK A;  4AD9 A;  2R2D A;  5K4M A;  3SFP A;  4NQ4 A;  4P62 A;  4U4L A;  3IEL A;  4BZ3 A;  3IEK A;  4B87 A;  4Z5Z A;  3I15 A;  4HKY A;  2OHJ A;  2QIN A;  4XUK A;  4ZO3 A;  1DXK A;  1WRA A;  3X2Y A;  2VW8 A;  5FQC A;  3PG4 A;  5EVB A;  2FU6 A;  3AF5 A;  2ZNB A;  4RM5 A;  2AZ4 A;  2GKL A;  5ACR A;  1JJT A;  2DOO A;  2WHG A;  2BG8 B;  3H3E A;  2BFK A;  3RPC A;  3ZWF A;  3ADR A;  5ACT A;  1MQO A;  2Q0J A;  2YNV B;  1QH5 A;  3A4Y A;  4GYU A;  5KIL A;  3DHA A;  2FM6 A;  5B1U A;  5HIS A;  4EXS A;  1K07 A;  4C1F A;  3IE2 A;  5FQB A;  5LLD A;  5A87 A;  4HL1 A;  2BFZ A;  4EXY A;  4TZ9 A;  5A0V A;  5LE1 A;  4WD6 A;  3X30 A;  4DIL A;  4F6H A;  4J5H A;  3SRX A;  4RAW A;  5B15 A;  2P1E A;  2BG2 A;  1VGN A;  5IQK A;  4AWZ A;  1BMC A;  4Z5Y A;  1WUP A;  3P2U A;  1SML A;  1BVT A;  4ZO2 A;  2ZO4 A;  4D1T A;  3I13 A;  4KEQ A;  2BG8 A;  2I7V A;  5LCF A;  1ZTC A;  3I0V A;  5HIO A;  4KEP A;  2OHH A;  4ZNB A;  3JXP A;  5AHR A;  4UWR B;  5AXO A;  4DIK A;  2XR1 A;  1X8I A;  3KNR A;  3RKJ A;  4UWO B;  1KR3 A;  1HLK A;  4EYL A;  2WYM C;  4XWW A;  4BP0 A;  2YNU A;  4HL2 A;  1YCG A;  4C1C A;  2UYX A;  2AIO A;  4C09 A;  1XM8 A;  3FAI A;  3MD7 A;  2HB9 A;  1ZKP A;  1WUO A;  4GYQ A;  2Y8B A;  5AHO A;  2YNW A;  2BFZ B;  4EYF A;  3RKK A;  3F9O A;  2CBN A;  2QED A;  4XWT A;  1M2X A;  2FU9 A;  2YNV A;  3BK1 A;  2Q0I A;  1QH3 A;  4FR7 A;  3IE0 A;  4Z67 A;  1JT1 A;  4FSB A;  3ZNB A;  4EY2 A;  1E5D A;  4EYB A;  4RL0 A;  3BV6 A;  5EVD A;  3I11 A;  4TYF A;  4Z6X A;  2BGA A;  2Q42 A;  4RL2 A;  2ZWR A;  3G1P A;  3KL7 A;  3VQZ A;  2NXA A;  5AEB A;  5HH5 A;  4C1H A;  2BTN A;  2WRS A;  3TP9 A;  4PVT A;  4NQ5 A;  2Y8A A;  2WYM A;  5EWA A;  2DKF A;  4UWS B;  2YNT B;  2Q9U A;  4C1G A;  2QJS A;  5ACS A;  4AX1 B;  4Z7R A;  4D1W A;  3ESH A;  4TZF A;  5LM6 A;  4FEK A;  2FK6 A;  2YNT A;  5FQA A;  4UAM A;  2BR6 A;  4AWY B;  4YSK A;  1A7T A;  5ACV A;  3Q6V A;  3AJ3 A;  4GCW A;  3SBL A;  2M5C A;  1L9Y A;  5LCA A;  2NYP A;  5ACQ A;  3AF6 A;  4JO0 A;  3DHB A;  4RAM A;  1DD6 A;  5HH6 A;  2OHI A;  5EV6 A;  5K4K A;  3VPE A;  2BC2 A;  3SW3 A;  3X2X A;  3PY5 A;  3SD9 A;  3BK2 A;  1WW1 A;  4F6Z A;  3BC2 A;  5KIK A;  3DHC A;  5EH9 A;  1X8G A;  5DPX A;  2H6A A;  5LS3 A;  4C1E A;  5LMC A;  3ZQ4 A;  3T3N A;  3DH8 A;  5A0T A;  3LVZ A;  5LCH A;  1X8H A;  1XTO A;  5EHT A;  4O98 A;  4J5F A;  2P18 A;  3SPU A;  4CHL A;  5ACU A;  4NQ2 A;  3KNS A;  5A5Z A;  5LSC A;  4UWP B;  3PY6 A;  4UA4 A;  2NZF A;  4TYT A;  3IDZ A;  5K4N A;  2ZZI A;  2NZE A;  2BG6 A;  4C1D A;  4TZB A;  2GFK A;  2GMN A;  2FU7 A;  2GCU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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