5ACWA

Vim-2-1, discovery of novel inhibitor scaffolds against the metallo- beta-lactamase vim-2 by spr based fragment screening
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
233
structure length
232
Chain Sequence
b'GEYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNRS'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords BETA-LACTAMASE
publication title Discovery of Novel Inhibitor Scaffolds Against the Metallo-Beta-Lactamase Vim-2 by Spr Based Fragment Screening
pubmed doi rcsb
source organism Pseudomonas aeruginosa
molecule tags Hydrolase
total genus 73
structure length 232
sequence length 233
chains with identical sequence B
ec nomenclature ec 3.5.2.6: Beta-lactamase.
pdb deposition date 2015-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5acwA00
2I7VA 4FSBA 2GFJA 4Z60A 5A0TA 5HH6A 2GFKA 5HIPA 1VGNA 4C1CA 3AJ3A 2ZWRA 4J5FA 5ACSA 1BC2A 4HL2A 4HL1A 3MD7A 2P4ZA 1BMCA 4XUKA 4P62A 3X30A 4O98A 3VPEA 5ACWA 4EXSA 3IEMA 3IEKA 1X8GA 2Y87A 3PG4A 2YNWA 4EY2A 2P18A 3I14A 4YSKA 1XTOA 4Z7RA 2WHGA 5EV8A 2BGAA 2QEDA 5LS3A 2GCUA 2ZO4A 5ACXA 1SMLA 3G1PA 5EHTA 5AXOA 4GYUA 2YNVB 5EVBA 3T3OA 2QJSA 5KILA 3S0ZA 3ESHA 4XWTA 4ZEJA 5A5ZA 2FK6A 3JXPA 5HISA 4TYTA 3ADRA 1JJTA 5FQBA 2WYLA 4UWOB 5A87A 1YCFA 4C1EA 5B15A 2YNUA 3H3EA 2OHJA 4ZO3A 4NQ2A 2BIBA 4C1DA 4D02A 1KR3A 4Z5YA 4UWPB 4H0DA 4UWSB 4D1WA 2YZ3A 4AWYB 4EYLA 3DHAA 2NZFA 5FQCA 2XR1A 1M2XA 4NQ4A 3PY6A 5LSCA 4NQ5A 4EXYA 4RL0A 3X2ZA 3PY5A 4WD6A 3VQZA 5FQAA 2FHXA 3ZNBA 4RM5A 1A8TA 4TYFA 4D1TA 3SFPA 5EV6A 3DH8A 3RKJA 2CBNA 5HIOA 2GKLA 5AEBA 1ZKPA 5A0VA 2Y8BA 2M5DA 2P97A 4EYFA 2AZ4A 3WXCA 1E5DA 4HKYA 2BG2A 4C1GA 3IE1A 2FM6A 1ZNBA 4KEPA 1WUPA 4PVOA 4FEKA 3SBLA 2BFKA 2YCBA 4FR7A 3I0VA 2Q0IA 1WW1A 2R2DA 2BTNA 3BK1A 1L9YA 4YSLA 2P1EA 2BG7A 1VJNA 2Y8AA 3FAIA 2BG8B 3ZR9A 4B87A 2GMNA 5EVDA 3ZQ4A 3AF5A 4UWRB 2NZEA 2VW8A 1ZTCA 4UBQA 3SW3A 4D1VA 2ZNBA 3ZWFA 4XWWA 2OHHA 1VMEA 5EH9A 4GCWA 4Z6XA 4C1FA 1JT1A 5EWAA 2FU7A 2BG8A 5EVKA 2A7MA 5LM6A 3I15A 5LLDA 4AWZA 5AYAA 5HIQA 2YNTB 2YNVA 5AXRA 2FU9A 4GYQA 4U4LA 1X8IA 1MQOA 2E7YA 2NYPA 4AX0B 2Q42A 1DXKA 3IOGA 3IE2A 1XM8A 5ACVA 2WRSA 5K4NA 2Q0JA 1BVTA 3AF6A 5KIKA 5EW0A 1YCHA 3T9MA 3R2UA 4UA4A 5B1UA 4BZ3A 3KNSA 2DKFA 1DD6A 3TP9A 3SPUA 2FU8A 4TZBA 2QDTA 5ACRA 5LCHA 1QH5A 4LE6A 2M5CA 2BC2A 2DOOA 4TZEA 2QDSA 4J5HA 4RBSA 5LE1A 4Z67A 5ACTA 5ACQA 5DPXA 1KO2A 2NXAA 5LCAA 4C1HA 5IQKA 4F6ZA 2FU6A 5HH4A 3BV6A 2BG6A 5LCFA 2OHIA 3I13A 4PVTA 4TZFA 4NQ6A 5K4MA 4TZ9A 5ACPA 5LMCA 5B3RA 3DHBA 2I7XA 5AHOA 3FCZA 4JO0A 2AIOA 3X2YA 4EYBA 4DILA 4UAMA 3BC2A 3RKKA 5K0WA 2HB9A 2BR6A 2BFZB 3BK2A 3L6NA 1P9EA 2ZZIA 4AX1B 4EFZA 2XF4A 2WYMC 2QINA 2BMIA 3A4YA 3IDZA 3KL7A 4RAWA 3F9OA 4ZNBA 3IE0A 3Q6VA 3P2UA 4F6HA 4Z5ZA 4YSBA 3SD9A 3IOFA 5HH5A 3I11A 4AD9A 4KEQA 3QH8A 2BFZA 5ACUA 1HLKA 1K07A 2WYMA 1JJEA 2FHXB 3RPCA 2H6AA 2UYXA 3IELA 4D1UA 4BP0A 1YCGA 2BFLA 5AHRA 2YNTA 2Q9UA 2I7TA 4C09A 3LVZA 4DIKA 1X8HA 4RL2A 3DHCA 3X2XA 1WUOA 3KNRA 4ZO2A 4V0HA 4CHLA 1WRAA 1DDKA 5K4KA 1A7TA 3SRXA 1QH3A 1Y44A 3T3NA 4RAMA 1KO3A
chains in the Genus database with same CATH superfamily
2I7VA 4FSBA 2GFJA 4Z60A 5A0TA 5HH6A 2GFKA 5HIPA 1VGNA 2CFUA 4C1CA 3AJ3A 2ZWRA 4J5FA 5ACSA 1BC2A 4HL2A 4HL1A 3MD7A 2P4ZA 1BMCA 4XUKA 4P62A 3X30A 4O98A 3VPEA 5ACWA 4EXSA 4AV7A 3IEMA 3IEKA 1X8GA 2Y87A 2CFZA 3PG4A 2YNWA 4EY2A 2P18A 3I14A 4YSKA 1XTOA 4Z7RA 2WHGA 5EV8A 2BGAA 2QEDA 5LS3A 2GCUA 2ZO4A 5ACXA 1SMLA 3G1PA 5EHTA 5AXOA 4GYUA 2YNVB 5EVBA 3T3OA 2QJSA 5KILA 3S0ZA 3ESHA 4XWTA 4ZEJA 5A5ZA 2FK6A 3JXPA 5HISA 4TYTA 3ADRA 1JJTA 5FQBA 2WYLA 4UWOB 5A87A 1YCFA 4C1EA 5B15A 2YNUA 3H3EA 2OHJA 4ZO3A 4NQ2A 2BIBA 4C1DA 4D02A 1KR3A 4Z5YA 4UWPB 4H0DA 4UWSB 4D1WA 2YZ3A 4AWYB 4EYLA 3DHAA 2NZFA 5FQCA 2XR1A 1M2XA 4NQ4A 3PY6A 5LSCA 4NQ5A 4EXYA 4RL0A 3X2ZA 3PY5A 4WD6A 3VQZA 5FQAA 2FHXA 3ZNBA 4RM5A 1A8TA 4TYFA 4D1TA 3SFPA 5EV6A 3DH8A 3RKJA 2CBNA 5HIOA 2GKLA 5AEBA 1ZKPA 5A0VA 2Y8BA 2M5DA 2P97A 4EYFA 2AZ4A 3WXCA 1E5DA 4HKYA 2BG2A 4C1GA 3IE1A 2FM6A 1ZNBA 4KEPA 1WUPA 4PVOA 4AXHA 4FEKA 3SBLA 2BFKA 2YCBA 4FR7A 3I0VA 2Q0IA 1WW1A 2R2DA 2BTNA 3BK1A 1L9YA 4YSLA 2P1EA 2BG7A 5AIJA 1VJNA 2Y8AA 3FAIA 2BG8B 3ZR9A 4NURA 4B87A 2GMNA 5EVDA 3ZQ4A 3AF5A 4UWRB 2NZEA 2VW8A 1ZTCA 4UBQA 3SW3A 4D1VA 2ZNBA 3ZWFA 4XWWA 2OHHA 1VMEA 5EH9A 4GCWA 4Z6XA 4C1FA 1JT1A 5EWAA 2FU7A 2BG8A 5EVKA 2A7MA 5LM6A 2CG3A 3I15A 5LLDA 4AWZA 5AYAA 5HIQA 2YNTB 2YNVA 5AXRA 2FU9A 4GYQA 4U4LA 1X8IA 1MQOA 2E7YA 2NYPA 4AX0B 2Q42A 1DXKA 3IOGA 3IE2A 1XM8A 5ACVA 2WRSA 5K4NA 2Q0JA 1BVTA 3AF6A 5KIKA 5EW0A 1YCHA 3T9MA 3R2UA 4UA4A 5B1UA 4BZ3A 3KNSA 2DKFA 1DD6A 3TP9A 3SPUA 2FU8A 4TZBA 2QDTA 5ACRA 5LCHA 1QH5A 4LE6A 2M5CA 2BC2A 2DOOA 4TZEA 2QDSA 4J5HA 4RBSA 5LE1A 4Z67A 5ACTA 5ACQA 5DPXA 1KO2A 2NXAA 5LCAA 4C1HA 5IQKA 4F6ZA 2FU6A 5HH4A 3BV6A 2BG6A 5LCFA 2OHIA 3I13A 4PVTA 4TZFA 4NQ6A 5K4MA 4TZ9A 5ACPA 5LMCA 5B3RA 5AJLA 3DHBA 2I7XA 5AHOA 3FCZA 4JO0A 2AIOA 3X2YA 4EYBA 4DILA 4UAMA 3BC2A 3RKKA 5K0WA 2CG2A 2HB9A 2BR6A 2BFZB 3BK2A 4PDXA 3L6NA 1P9EA 2ZZIA 4AX1B 4EFZA 2XF4A 2WYMC 2QINA 2BMIA 3A4YA 3IDZA 3KL7A 4RAWA 3F9OA 5A23A 4ZNBA 3IE0A 3Q6VA 3P2UA 4F6HA 4Z5ZA 4YSBA 3SD9A 3IOFA 5HH5A 3I11A 4AD9A 4KEQA 3QH8A 2BFZA 5ACUA 1HLKA 1K07A 2WYMA 1JJEA 2FHXB 3RPCA 2H6AA 2UYXA 3IELA 4D1UA 4BP0A 1YCGA 2BFLA 5AHRA 2YNTA 2Q9UA 2I7TA 4C09A 3LVZA 4DIKA 1X8HA 4RL2A 3DHCA 3X2XA 1WUOA 3KNRA 4ZO2A 4V0HA 4CHLA 2YHEA 1WRAA 1DDKA 5K4KA 1A7TA 3SRXA 1QH3A 1Y44A 3T3NA 4RAMA 1KO3A
chains in the Genus database with same CATH topology
2I7VA 4FSBA 2GFJA 4Z60A 5A0TA 5HH6A 2GFKA 5HIPA 1VGNA 4C1CA 3AJ3A 2ZWRA 4J5FA 5ACSA 1BC2A 4HL2A 4HL1A 3MD7A 2P4ZA 1BMCA 4XUKA 4P62A 3X30A 4O98A 3VPEA 5ACWA 4EXSA 3IEMA 3IEKA 1X8GA 2Y87A 3PG4A 2YNWA 4EY2A 2P18A 3I14A 4YSKA 1XTOA 4Z7RA 2WHGA 5EV8A 2BGAA 2QEDA 5LS3A 2GCUA 2ZO4A 5ACXA 1SMLA 3G1PA 5EHTA 5AXOA 4GYUA 2YNVB 5EVBA 3T3OA 2QJSA 5KILA 3S0ZA 3ESHA 4XWTA 4ZEJA 5A5ZA 2FK6A 3JXPA 5HISA 4TYTA 3ADRA 1JJTA 5FQBA 2WYLA 4UWOB 5A87A 1YCFA 4C1EA 5B15A 2YNUA 3H3EA 2OHJA 4ZO3A 4NQ2A 2BIBA 4C1DA 4D02A 1KR3A 4Z5YA 4UWPB 4H0DA 4UWSB 4D1WA 2YZ3A 4AWYB 4EYLA 3DHAA 2NZFA 5FQCA 2XR1A 1M2XA 4NQ4A 3PY6A 5LSCA 4NQ5A 4EXYA 4RL0A 3X2ZA 3PY5A 4WD6A 3VQZA 5FQAA 2FHXA 3ZNBA 4RM5A 1A8TA 4TYFA 4D1TA 3SFPA 5EV6A 3DH8A 3RKJA 2CBNA 5HIOA 2GKLA 5AEBA 1ZKPA 5A0VA 2Y8BA 2M5DA 2P97A 4EYFA 2AZ4A 3WXCA 1E5DA 4HKYA 2BG2A 4C1GA 3IE1A 2FM6A 1ZNBA 4KEPA 1WUPA 4PVOA 4FEKA 3SBLA 2BFKA 2YCBA 4FR7A 3I0VA 2Q0IA 1WW1A 2R2DA 2BTNA 3BK1A 1L9YA 4YSLA 2P1EA 2BG7A 1VJNA 2Y8AA 3FAIA 2BG8B 3ZR9A 4B87A 2GMNA 5EVDA 3ZQ4A 3AF5A 4UWRB 2NZEA 2VW8A 1ZTCA 4UBQA 3SW3A 4D1VA 2ZNBA 3ZWFA 4XWWA 2OHHA 1VMEA 5EH9A 4GCWA 4Z6XA 4C1FA 1JT1A 5EWAA 2FU7A 2BG8A 5EVKA 2A7MA 5LM6A 3I15A 5LLDA 4AWZA 5AYAA 5HIQA 2YNTB 2YNVA 5AXRA 2FU9A 4GYQA 4U4LA 1X8IA 1MQOA 2E7YA 2NYPA 4AX0B 2Q42A 1DXKA 3IOGA 3IE2A 1XM8A 5ACVA 2WRSA 5K4NA 2Q0JA 1BVTA 3AF6A 5KIKA 5EW0A 1YCHA 3T9MA 3R2UA 4UA4A 5B1UA 4BZ3A 3KNSA 2DKFA 1DD6A 3TP9A 3SPUA 2FU8A 4TZBA 2QDTA 5ACRA 5LCHA 1QH5A 4LE6A 2M5CA 2BC2A 2DOOA 4TZEA 2QDSA 4J5HA 4RBSA 5LE1A 4Z67A 5ACTA 5ACQA 5DPXA 1KO2A 2NXAA 5LCAA 4C1HA 5IQKA 4F6ZA 2FU6A 5HH4A 3BV6A 2BG6A 5LCFA 2OHIA 3I13A 4PVTA 4TZFA 4NQ6A 5K4MA 4TZ9A 5ACPA 5LMCA 5B3RA 3DHBA 2I7XA 5AHOA 3FCZA 4JO0A 2AIOA 3X2YA 4EYBA 4DILA 4UAMA 3BC2A 3RKKA 5K0WA 2HB9A 2BR6A 2BFZB 3BK2A 3L6NA 1P9EA 2ZZIA 4AX1B 4EFZA 2XF4A 2WYMC 2QINA 2BMIA 3A4YA 3IDZA 3KL7A 4RAWA 3F9OA 4ZNBA 3IE0A 3Q6VA 3P2UA 4F6HA 4Z5ZA 4YSBA 3SD9A 3IOFA 5HH5A 3I11A 4AD9A 4KEQA 3QH8A 2BFZA 5ACUA 1HLKA 1K07A 2WYMA 1JJEA 2FHXB 3RPCA 2H6AA 2UYXA 3IELA 4D1UA 4BP0A 1YCGA 2BFLA 5AHRA 2YNTA 2Q9UA 2I7TA 4C09A 3LVZA 4DIKA 1X8HA 4RL2A 3DHCA 3X2XA 1WUOA 3KNRA 4ZO2A 4V0HA 4CHLA 1WRAA 1DDKA 5K4KA 1A7TA 3SRXA 1QH3A 1Y44A 3T3NA 4RAMA 1KO3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2I7V A;  4FSB A;  2GFJ A;  4Z60 A;  5A0T A;  5HH6 A;  2GFK A;  5HIP A;  1VGN A;  4C1C A;  3AJ3 A;  2ZWR A;  4J5F A;  5ACS A;  1BC2 A;  4HL2 A;  4HL1 A;  3MD7 A;  2P4Z A;  1BMC A;  4XUK A;  4P62 A;  3X30 A;  4O98 A;  3VPE A;  5ACW A;  4EXS A;  3IEM A;  3IEK A;  1X8G A;  2Y87 A;  3PG4 A;  2YNW A;  4EY2 A;  2P18 A;  3I14 A;  4YSK A;  1XTO A;  4Z7R A;  2WHG A;  5EV8 A;  2BGA A;  2QED A;  5LS3 A;  2GCU A;  2ZO4 A;  5ACX A;  1SML A;  3G1P A;  5EHT A;  5AXO A;  4GYU A;  2YNV B;  5EVB A;  3T3O A;  2QJS A;  5KIL A;  3S0Z A;  3ESH A;  4XWT A;  4ZEJ A;  5A5Z A;  2FK6 A;  3JXP A;  5HIS A;  4TYT A;  3ADR A;  1JJT A;  5FQB A;  2WYL A;  4UWO B;  5A87 A;  1YCF A;  4C1E A;  5B15 A;  2YNU A;  3H3E A;  2OHJ A;  4ZO3 A;  4NQ2 A;  2BIB A;  4C1D A;  4D02 A;  1KR3 A;  4Z5Y A;  4UWP B;  4H0D A;  4UWS B;  4D1W A;  2YZ3 A;  4AWY B;  4EYL A;  3DHA A;  2NZF A;  5FQC A;  2XR1 A;  1M2X A;  4NQ4 A;  3PY6 A;  5LSC A;  4NQ5 A;  4EXY A;  4RL0 A;  3X2Z A;  3PY5 A;  4WD6 A;  3VQZ A;  5FQA A;  2FHX A;  3ZNB A;  4RM5 A;  1A8T A;  4TYF A;  4D1T A;  3SFP A;  5EV6 A;  3DH8 A;  3RKJ A;  2CBN A;  5HIO A;  2GKL A;  5AEB A;  1ZKP A;  5A0V A;  2Y8B A;  2M5D A;  2P97 A;  4EYF A;  2AZ4 A;  3WXC A;  1E5D A;  4HKY A;  2BG2 A;  4C1G A;  3IE1 A;  2FM6 A;  1ZNB A;  4KEP A;  1WUP A;  4PVO A;  4FEK A;  3SBL A;  2BFK A;  2YCB A;  4FR7 A;  3I0V A;  2Q0I A;  1WW1 A;  2R2D A;  2BTN A;  3BK1 A;  1L9Y A;  4YSL A;  2P1E A;  2BG7 A;  1VJN A;  2Y8A A;  3FAI A;  2BG8 B;  3ZR9 A;  4B87 A;  2GMN A;  5EVD A;  3ZQ4 A;  3AF5 A;  4UWR B;  2NZE A;  2VW8 A;  1ZTC A;  4UBQ A;  3SW3 A;  4D1V A;  2ZNB A;  3ZWF A;  4XWW A;  2OHH A;  1VME A;  5EH9 A;  4GCW A;  4Z6X A;  4C1F A;  1JT1 A;  5EWA A;  2FU7 A;  2BG8 A;  5EVK A;  2A7M A;  5LM6 A;  3I15 A;  5LLD A;  4AWZ A;  5AYA A;  5HIQ A;  2YNT B;  2YNV A;  5AXR A;  2FU9 A;  4GYQ A;  4U4L A;  1X8I A;  1MQO A;  2E7Y A;  2NYP A;  4AX0 B;  2Q42 A;  1DXK A;  3IOG A;  3IE2 A;  1XM8 A;  5ACV A;  2WRS A;  5K4N A;  2Q0J A;  1BVT A;  3AF6 A;  5KIK A;  5EW0 A;  1YCH A;  3T9M A;  3R2U A;  4UA4 A;  5B1U A;  4BZ3 A;  3KNS A;  2DKF A;  1DD6 A;  3TP9 A;  3SPU A;  2FU8 A;  4TZB A;  2QDT A;  5ACR A;  5LCH A;  1QH5 A;  4LE6 A;  2M5C A;  2BC2 A;  2DOO A;  4TZE A;  2QDS A;  4J5H A;  4RBS A;  5LE1 A;  4Z67 A;  5ACT A;  5ACQ A;  5DPX A;  1KO2 A;  2NXA A;  5LCA A;  4C1H A;  5IQK A;  4F6Z A;  2FU6 A;  5HH4 A;  3BV6 A;  2BG6 A;  5LCF A;  2OHI A;  3I13 A;  4PVT A;  4TZF A;  4NQ6 A;  5K4M A;  4TZ9 A;  5ACP A;  5LMC A;  5B3R A;  3DHB A;  2I7X A;  5AHO A;  3FCZ A;  4JO0 A;  2AIO A;  3X2Y A;  4EYB A;  4DIL A;  4UAM A;  3BC2 A;  3RKK A;  5K0W A;  2HB9 A;  2BR6 A;  2BFZ B;  3BK2 A;  3L6N A;  1P9E A;  2ZZI A;  4AX1 B;  4EFZ A;  2XF4 A;  2WYM C;  2QIN A;  2BMI A;  3A4Y A;  3IDZ A;  3KL7 A;  4RAW A;  3F9O A;  4ZNB A;  3IE0 A;  3Q6V A;  3P2U A;  4F6H A;  4Z5Z A;  4YSB A;  3SD9 A;  3IOF A;  5HH5 A;  3I11 A;  4AD9 A;  4KEQ A;  3QH8 A;  2BFZ A;  5ACU A;  1HLK A;  1K07 A;  2WYM A;  1JJE A;  2FHX B;  3RPC A;  2H6A A;  2UYX A;  3IEL A;  4D1U A;  4BP0 A;  1YCG A;  2BFL A;  5AHR A;  2YNT A;  2Q9U A;  2I7T A;  4C09 A;  3LVZ A;  4DIK A;  1X8H A;  4RL2 A;  3DHC A;  3X2X A;  1WUO A;  3KNR A;  4ZO2 A;  4V0H A;  4CHL A;  1WRA A;  1DDK A;  5K4K A;  1A7T A;  3SRX A;  1QH3 A;  1Y44 A;  3T3N A;  4RAM A;  1KO3 A; 
#chains in the Genus database with same CATH topology
 2I7V A;  4FSB A;  2GFJ A;  4Z60 A;  5A0T A;  5HH6 A;  2GFK A;  5HIP A;  1VGN A;  2CFU A;  4C1C A;  3AJ3 A;  2ZWR A;  4J5F A;  5ACS A;  1BC2 A;  4HL2 A;  4HL1 A;  3MD7 A;  2P4Z A;  1BMC A;  4XUK A;  4P62 A;  3X30 A;  4O98 A;  3VPE A;  5ACW A;  4EXS A;  4AV7 A;  3IEM A;  3IEK A;  1X8G A;  2Y87 A;  2CFZ A;  3PG4 A;  2YNW A;  4EY2 A;  2P18 A;  3I14 A;  4YSK A;  1XTO A;  4Z7R A;  2WHG A;  5EV8 A;  2BGA A;  2QED A;  5LS3 A;  2GCU A;  2ZO4 A;  5ACX A;  1SML A;  3G1P A;  5EHT A;  5AXO A;  4GYU A;  2YNV B;  5EVB A;  3T3O A;  2QJS A;  5KIL A;  3S0Z A;  3ESH A;  4XWT A;  4ZEJ A;  5A5Z A;  2FK6 A;  3JXP A;  5HIS A;  4TYT A;  3ADR A;  1JJT A;  5FQB A;  2WYL A;  4UWO B;  5A87 A;  1YCF A;  4C1E A;  5B15 A;  2YNU A;  3H3E A;  2OHJ A;  4ZO3 A;  4NQ2 A;  2BIB A;  4C1D A;  4D02 A;  1KR3 A;  4Z5Y A;  4UWP B;  4H0D A;  4UWS B;  4D1W A;  2YZ3 A;  4AWY B;  4EYL A;  3DHA A;  2NZF A;  5FQC A;  2XR1 A;  1M2X A;  4NQ4 A;  3PY6 A;  5LSC A;  4NQ5 A;  4EXY A;  4RL0 A;  3X2Z A;  3PY5 A;  4WD6 A;  3VQZ A;  5FQA A;  2FHX A;  3ZNB A;  4RM5 A;  1A8T A;  4TYF A;  4D1T A;  3SFP A;  5EV6 A;  3DH8 A;  3RKJ A;  2CBN A;  5HIO A;  2GKL A;  5AEB A;  1ZKP A;  5A0V A;  2Y8B A;  2M5D A;  2P97 A;  4EYF A;  2AZ4 A;  3WXC A;  1E5D A;  4HKY A;  2BG2 A;  4C1G A;  3IE1 A;  2FM6 A;  1ZNB A;  4KEP A;  1WUP A;  4PVO A;  4AXH A;  4FEK A;  3SBL A;  2BFK A;  2YCB A;  4FR7 A;  3I0V A;  2Q0I A;  1WW1 A;  2R2D A;  2BTN A;  3BK1 A;  1L9Y A;  4YSL A;  2P1E A;  2BG7 A;  5AIJ A;  1VJN A;  2Y8A A;  3FAI A;  2BG8 B;  3ZR9 A;  4NUR A;  4B87 A;  2GMN A;  5EVD A;  3ZQ4 A;  3AF5 A;  4UWR B;  2NZE A;  2VW8 A;  1ZTC A;  4UBQ A;  3SW3 A;  4D1V A;  2ZNB A;  3ZWF A;  4XWW A;  2OHH A;  1VME A;  5EH9 A;  4GCW A;  4Z6X A;  4C1F A;  1JT1 A;  5EWA A;  2FU7 A;  2BG8 A;  5EVK A;  2A7M A;  5LM6 A;  2CG3 A;  3I15 A;  5LLD A;  4AWZ A;  5AYA A;  5HIQ A;  2YNT B;  2YNV A;  5AXR A;  2FU9 A;  4GYQ A;  4U4L A;  1X8I A;  1MQO A;  2E7Y A;  2NYP A;  4AX0 B;  2Q42 A;  1DXK A;  3IOG A;  3IE2 A;  1XM8 A;  5ACV A;  2WRS A;  5K4N A;  2Q0J A;  1BVT A;  3AF6 A;  5KIK A;  5EW0 A;  1YCH A;  3T9M A;  3R2U A;  4UA4 A;  5B1U A;  4BZ3 A;  3KNS A;  2DKF A;  1DD6 A;  3TP9 A;  3SPU A;  2FU8 A;  4TZB A;  2QDT A;  5ACR A;  5LCH A;  1QH5 A;  4LE6 A;  2M5C A;  2BC2 A;  2DOO A;  4TZE A;  2QDS A;  4J5H A;  4RBS A;  5LE1 A;  4Z67 A;  5ACT A;  5ACQ A;  5DPX A;  1KO2 A;  2NXA A;  5LCA A;  4C1H A;  5IQK A;  4F6Z A;  2FU6 A;  5HH4 A;  3BV6 A;  2BG6 A;  5LCF A;  2OHI A;  3I13 A;  4PVT A;  4TZF A;  4NQ6 A;  5K4M A;  4TZ9 A;  5ACP A;  5LMC A;  5B3R A;  5AJL A;  3DHB A;  2I7X A;  5AHO A;  3FCZ A;  4JO0 A;  2AIO A;  3X2Y A;  4EYB A;  4DIL A;  4UAM A;  3BC2 A;  3RKK A;  5K0W A;  2CG2 A;  2HB9 A;  2BR6 A;  2BFZ B;  3BK2 A;  4PDX A;  3L6N A;  1P9E A;  2ZZI A;  4AX1 B;  4EFZ A;  2XF4 A;  2WYM C;  2QIN A;  2BMI A;  3A4Y A;  3IDZ A;  3KL7 A;  4RAW A;  3F9O A;  5A23 A;  4ZNB A;  3IE0 A;  3Q6V A;  3P2U A;  4F6H A;  4Z5Z A;  4YSB A;  3SD9 A;  3IOF A;  5HH5 A;  3I11 A;  4AD9 A;  4KEQ A;  3QH8 A;  2BFZ A;  5ACU A;  1HLK A;  1K07 A;  2WYM A;  1JJE A;  2FHX B;  3RPC A;  2H6A A;  2UYX A;  3IEL A;  4D1U A;  4BP0 A;  1YCG A;  2BFL A;  5AHR A;  2YNT A;  2Q9U A;  2I7T A;  4C09 A;  3LVZ A;  4DIK A;  1X8H A;  4RL2 A;  3DHC A;  3X2X A;  1WUO A;  3KNR A;  4ZO2 A;  4V0H A;  4CHL A;  2YHE A;  1WRA A;  1DDK A;  5K4K A;  1A7T A;  3SRX A;  1QH3 A;  1Y44 A;  3T3N A;  4RAM A;  1KO3 A; 
#chains in the Genus database with same CATH homology
 2I7V A;  4FSB A;  2GFJ A;  4Z60 A;  5A0T A;  5HH6 A;  2GFK A;  5HIP A;  1VGN A;  4C1C A;  3AJ3 A;  2ZWR A;  4J5F A;  5ACS A;  1BC2 A;  4HL2 A;  4HL1 A;  3MD7 A;  2P4Z A;  1BMC A;  4XUK A;  4P62 A;  3X30 A;  4O98 A;  3VPE A;  5ACW A;  4EXS A;  3IEM A;  3IEK A;  1X8G A;  2Y87 A;  3PG4 A;  2YNW A;  4EY2 A;  2P18 A;  3I14 A;  4YSK A;  1XTO A;  4Z7R A;  2WHG A;  5EV8 A;  2BGA A;  2QED A;  5LS3 A;  2GCU A;  2ZO4 A;  5ACX A;  1SML A;  3G1P A;  5EHT A;  5AXO A;  4GYU A;  2YNV B;  5EVB A;  3T3O A;  2QJS A;  5KIL A;  3S0Z A;  3ESH A;  4XWT A;  4ZEJ A;  5A5Z A;  2FK6 A;  3JXP A;  5HIS A;  4TYT A;  3ADR A;  1JJT A;  5FQB A;  2WYL A;  4UWO B;  5A87 A;  1YCF A;  4C1E A;  5B15 A;  2YNU A;  3H3E A;  2OHJ A;  4ZO3 A;  4NQ2 A;  2BIB A;  4C1D A;  4D02 A;  1KR3 A;  4Z5Y A;  4UWP B;  4H0D A;  4UWS B;  4D1W A;  2YZ3 A;  4AWY B;  4EYL A;  3DHA A;  2NZF A;  5FQC A;  2XR1 A;  1M2X A;  4NQ4 A;  3PY6 A;  5LSC A;  4NQ5 A;  4EXY A;  4RL0 A;  3X2Z A;  3PY5 A;  4WD6 A;  3VQZ A;  5FQA A;  2FHX A;  3ZNB A;  4RM5 A;  1A8T A;  4TYF A;  4D1T A;  3SFP A;  5EV6 A;  3DH8 A;  3RKJ A;  2CBN A;  5HIO A;  2GKL A;  5AEB A;  1ZKP A;  5A0V A;  2Y8B A;  2M5D A;  2P97 A;  4EYF A;  2AZ4 A;  3WXC A;  1E5D A;  4HKY A;  2BG2 A;  4C1G A;  3IE1 A;  2FM6 A;  1ZNB A;  4KEP A;  1WUP A;  4PVO A;  4FEK A;  3SBL A;  2BFK A;  2YCB A;  4FR7 A;  3I0V A;  2Q0I A;  1WW1 A;  2R2D A;  2BTN A;  3BK1 A;  1L9Y A;  4YSL A;  2P1E A;  2BG7 A;  1VJN A;  2Y8A A;  3FAI A;  2BG8 B;  3ZR9 A;  4B87 A;  2GMN A;  5EVD A;  3ZQ4 A;  3AF5 A;  4UWR B;  2NZE A;  2VW8 A;  1ZTC A;  4UBQ A;  3SW3 A;  4D1V A;  2ZNB A;  3ZWF A;  4XWW A;  2OHH A;  1VME A;  5EH9 A;  4GCW A;  4Z6X A;  4C1F A;  1JT1 A;  5EWA A;  2FU7 A;  2BG8 A;  5EVK A;  2A7M A;  5LM6 A;  3I15 A;  5LLD A;  4AWZ A;  5AYA A;  5HIQ A;  2YNT B;  2YNV A;  5AXR A;  2FU9 A;  4GYQ A;  4U4L A;  1X8I A;  1MQO A;  2E7Y A;  2NYP A;  4AX0 B;  2Q42 A;  1DXK A;  3IOG A;  3IE2 A;  1XM8 A;  5ACV A;  2WRS A;  5K4N A;  2Q0J A;  1BVT A;  3AF6 A;  5KIK A;  5EW0 A;  1YCH A;  3T9M A;  3R2U A;  4UA4 A;  5B1U A;  4BZ3 A;  3KNS A;  2DKF A;  1DD6 A;  3TP9 A;  3SPU A;  2FU8 A;  4TZB A;  2QDT A;  5ACR A;  5LCH A;  1QH5 A;  4LE6 A;  2M5C A;  2BC2 A;  2DOO A;  4TZE A;  2QDS A;  4J5H A;  4RBS A;  5LE1 A;  4Z67 A;  5ACT A;  5ACQ A;  5DPX A;  1KO2 A;  2NXA A;  5LCA A;  4C1H A;  5IQK A;  4F6Z A;  2FU6 A;  5HH4 A;  3BV6 A;  2BG6 A;  5LCF A;  2OHI A;  3I13 A;  4PVT A;  4TZF A;  4NQ6 A;  5K4M A;  4TZ9 A;  5ACP A;  5LMC A;  5B3R A;  3DHB A;  2I7X A;  5AHO A;  3FCZ A;  4JO0 A;  2AIO A;  3X2Y A;  4EYB A;  4DIL A;  4UAM A;  3BC2 A;  3RKK A;  5K0W A;  2HB9 A;  2BR6 A;  2BFZ B;  3BK2 A;  3L6N A;  1P9E A;  2ZZI A;  4AX1 B;  4EFZ A;  2XF4 A;  2WYM C;  2QIN A;  2BMI A;  3A4Y A;  3IDZ A;  3KL7 A;  4RAW A;  3F9O A;  4ZNB A;  3IE0 A;  3Q6V A;  3P2U A;  4F6H A;  4Z5Z A;  4YSB A;  3SD9 A;  3IOF A;  5HH5 A;  3I11 A;  4AD9 A;  4KEQ A;  3QH8 A;  2BFZ A;  5ACU A;  1HLK A;  1K07 A;  2WYM A;  1JJE A;  2FHX B;  3RPC A;  2H6A A;  2UYX A;  3IEL A;  4D1U A;  4BP0 A;  1YCG A;  2BFL A;  5AHR A;  2YNT A;  2Q9U A;  2I7T A;  4C09 A;  3LVZ A;  4DIK A;  1X8H A;  4RL2 A;  3DHC A;  3X2X A;  1WUO A;  3KNR A;  4ZO2 A;  4V0H A;  4CHL A;  1WRA A;  1DDK A;  5K4K A;  1A7T A;  3SRX A;  1QH3 A;  1Y44 A;  3T3N A;  4RAM A;  1KO3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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