5ACWA

Vim-2-1, discovery of novel inhibitor scaffolds against the metallo- beta-lactamase vim-2 by spr based fragment screening
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
233
structure length
232
Chain Sequence
GEYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNRS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords BETA-LACTAMASE
publication title Discovery of Novel Inhibitor Scaffolds Against the Metallo-Beta-Lactamase Vim-2 by Spr Based Fragment Screening
pubmed doi rcsb
source organism Pseudomonas aeruginosa
molecule tags Hydrolase
total genus 73
structure length 232
sequence length 233
chains with identical sequence B
ec nomenclature ec 3.5.2.6: Beta-lactamase.
pdb deposition date 2015-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5acwA00
3ESHA 2Y8AA 2FU7A 3T3OA 1L9YA 5HISA 3T9MA 5LCHA 5EW0A 3IOGA 2HB9A 4PVTA 4DIKA 3ADRA 3FAIA 4P62A 1YCGA 5EHTA 2I7VA 4UBQA 2NXAA 4D02A 1X8GA 2BG7A 5B15A 4DILA 5ACTA 2VW8A 5ACWA 3TP9A 1DDKA 4AWZA 3S0ZA 3SFPA 3SBLA 1YCFA 5LLDA 1DXKA 2M5CA 3SW3A 3X30A 2QDSA 2Q9UA 2GFKA 2YCBA 3SRXA 3FCZA 2DKFA 2YNTB 4Z6XA 4TZ9A 2Q0JA 2CBNA 1QH3A 2FK6A 2WYMC 4UWSB 2WRSA 4TZEA 3PY6A 4Z60A 3RKKA 2YZ3A 3IE2A 4J5FA 4C1EA 4GYUA 4ZO3A 4D1WA 2UYXA 2ZNBA 1VJNA 3A4YA 3DHBA 2BFZB 4GCWA 4XWWA 1XTOA 2GMNA 1YCHA 4BP0A 2WYLA 4TYTA 2NZEA 5KILA 5FQBA 2QDTA 2YNUA 4EYFA 1DD6A 3AF6A 3Q6VA 3IDZA 4KEQA 4F6ZA 2BGAA 4H0DA 4J5HA 5LSCA 2XF4A 1X8HA 5FQCA 2P1EA 1WUOA 4D1UA 3X2ZA 3IE0A 2BMIA 5LCAA 4EXSA 2OHJA 2GFJA 4ZNBA 3IELA 1HLKA 2WHGA 4RL0A 5LE1A 5B1UA 5ACPA 3LVZA 4KEPA 1E5DA 3KNSA 3L6NA 3AF5A 2FU6A 3ZQ4A 2I7XA 2P97A 2QJSA 4V0HA 2BG8B 4FEKA 4YSKA 2FHXA 4C1HA 4ZEJA 2YNVA 5EVKA 4AX0B 1WW1A 2XR1A 5ACVA 5A0VA 1JJTA 4YSBA 4YSLA 2A7MA 3R2UA 4Z67A 3T3NA 2FM6A 2FU8A 4FR7A 5HH5A 2GCUA 4C1GA 4HKYA 4RL2A 4UWOB 5K4NA 2BC2A 5B3RA 1KR3A 4EYLA 5HIPA 5EVDA 3KNRA 4RBSA 4Z5YA 4EY2A 3ZWFA 2QINA 4C09A 3P2UA 3QH8A 2Y8BA 1WUPA 3RPCA 4F6HA 3WXCA 5ACXA 2I7TA 3X2YA 3I13A 4U4LA 3IE1A 2P4ZA 1KO2A 1VMEA 5LCFA 4TZBA 1K07A 2H6AA 5EWAA 4C1CA 5EVBA 2P18A 2BR6A 4LE6A 2QEDA 4NQ2A 2Q42A 3G1PA 4NQ6A 1X8IA 2YNWA 2E7YA 1JT1A 5A5ZA 3IEKA 1ZNBA 4CHLA 2FU9A 2YNTA 5IQKA 2Q0IA 1XM8A 3PG4A 4B87A 2BG2A 3F9OA 4PVOA 5EV6A 4AX1B 4UA4A 4C1FA 3I0VA 2R2DA 3DHCA 4RAMA 3ZNBA 2DOOA 2BFZA 2GKLA 1BMCA 3VPEA 2M5DA 4WD6A 5HH4A 4GYQA 3PY5A 4D1VA 4TYFA 2BFKA 2AIOA 1WRAA 4UAMA 5AHRA 3VQZA 4UWRB 5EH9A 1KO3A 4XUKA 4NQ5A 5HIOA 2Y87A 4AWYB 1P9EA 3KL7A 5K4MA 3I15A 5AXRA 4JO0A 3BV6A 4Z7RA 3BK1A 1QH5A 5EV8A 5A87A 5DPXA 3MD7A 5AXOA 4RAWA 4NQ4A 4TZFA 1ZTCA 3IEMA 4ZO2A 2AZ4A 5ACRA 2BTNA 4HL1A 2NYPA 2ZZIA 1A8TA 3BK2A 2BFLA 5AYAA 4EFZA 5HH6A 1VGNA 4D1TA 2BG8A 1Y44A 3DHAA 4Z5ZA 1M2XA 3IOFA 1A7TA 3RKJA 2NZFA 5AHOA 5FQAA 3JXPA 2OHIA 3X2XA 4EYBA 3ZR9A 2BG6A 4RM5A 2OHHA 2ZO4A 3AJ3A 3H3EA 5A0TA 4FSBA 3I11A 4BZ3A 2WYMA 3SPUA 1SMLA 4HL2A 5KIKA 5AEBA 5HIQA 4O98A 4EXYA 1JJEA 4UWPB 2FHXB 2BIBA 2ZWRA 5ACQA 2YNVB 5K4KA 5ACSA 5LS3A 4AD9A 1BC2A 5LM6A 1ZKPA 5K0WA 5ACUA 3DH8A 3BC2A 3SD9A 5LMCA 4XWTA 4C1DA 1MQOA 1BVTA 3I14A
chains in the Genus database with same CATH superfamily
3ESHA 2Y8AA 2FU7A 3T3OA 1L9YA 5HISA 3T9MA 5LCHA 5EW0A 3IOGA 2HB9A 4PVTA 4DIKA 3ADRA 5AIJA 3FAIA 4P62A 1YCGA 5EHTA 2I7VA 4UBQA 2NXAA 4D02A 1X8GA 2CG2A 2BG7A 5B15A 4DILA 5ACTA 2VW8A 5ACWA 3TP9A 1DDKA 4AXHA 4AWZA 3S0ZA 3SFPA 3SBLA 1YCFA 5LLDA 1DXKA 2M5CA 3SW3A 3X30A 2QDSA 2Q9UA 2GFKA 2YCBA 3SRXA 3FCZA 2DKFA 2YNTB 4Z6XA 4TZ9A 2Q0JA 2CBNA 1QH3A 2FK6A 2WYMC 4UWSB 2WRSA 4TZEA 3PY6A 4Z60A 3RKKA 2YZ3A 3IE2A 4J5FA 4C1EA 4GYUA 2CG3A 4ZO3A 4D1WA 2UYXA 2ZNBA 1VJNA 3A4YA 3DHBA 2BFZB 4GCWA 4XWWA 1XTOA 2GMNA 1YCHA 4BP0A 4PDXA 2WYLA 4TYTA 2NZEA 5KILA 5FQBA 2QDTA 2YNUA 4EYFA 1DD6A 3AF6A 3Q6VA 3IDZA 4KEQA 4F6ZA 2BGAA 4H0DA 4J5HA 5LSCA 2XF4A 1X8HA 5FQCA 2P1EA 1WUOA 4D1UA 3X2ZA 3IE0A 2BMIA 5LCAA 4EXSA 2OHJA 2GFJA 4ZNBA 3IELA 1HLKA 2WHGA 4RL0A 5LE1A 5B1UA 5ACPA 3LVZA 4KEPA 1E5DA 3KNSA 3L6NA 3AF5A 2FU6A 3ZQ4A 2I7XA 2P97A 2QJSA 4V0HA 2BG8B 4FEKA 4YSKA 2FHXA 4C1HA 4ZEJA 2YNVA 4AV7A 5EVKA 4AX0B 1WW1A 2XR1A 5ACVA 5A0VA 1JJTA 4YSBA 4YSLA 2A7MA 3R2UA 4Z67A 3T3NA 4NURA 2FM6A 2FU8A 4FR7A 5HH5A 2GCUA 4C1GA 4HKYA 4RL2A 4UWOB 5K4NA 2BC2A 5B3RA 1KR3A 4EYLA 5HIPA 5EVDA 3KNRA 4RBSA 4Z5YA 4EY2A 3ZWFA 2QINA 4C09A 3P2UA 3QH8A 2Y8BA 1WUPA 3RPCA 4F6HA 3WXCA 5ACXA 2I7TA 3X2YA 3I13A 4U4LA 3IE1A 2P4ZA 1KO2A 1VMEA 5LCFA 4TZBA 1K07A 2H6AA 5EWAA 4C1CA 5EVBA 2P18A 2BR6A 4LE6A 2QEDA 4NQ2A 2Q42A 3G1PA 4NQ6A 1X8IA 2YNWA 2E7YA 1JT1A 5A5ZA 3IEKA 1ZNBA 4CHLA 2FU9A 2YNTA 5IQKA 2Q0IA 1XM8A 3PG4A 4B87A 2BG2A 3F9OA 4PVOA 5EV6A 4AX1B 4UA4A 4C1FA 2CFZA 3I0VA 2R2DA 2YHEA 3DHCA 4RAMA 3ZNBA 2DOOA 2BFZA 2GKLA 1BMCA 3VPEA 2M5DA 4WD6A 5HH4A 4GYQA 3PY5A 4D1VA 4TYFA 2BFKA 2AIOA 1WRAA 4UAMA 5AHRA 3VQZA 4UWRB 5EH9A 1KO3A 4XUKA 4NQ5A 5HIOA 2Y87A 4AWYB 1P9EA 3KL7A 5K4MA 3I15A 5AXRA 4JO0A 3BV6A 4Z7RA 3BK1A 1QH5A 5EV8A 5A87A 5DPXA 3MD7A 5AXOA 4RAWA 4NQ4A 4TZFA 1ZTCA 3IEMA 2CFUA 4ZO2A 2AZ4A 5ACRA 2BTNA 4HL1A 2NYPA 2ZZIA 1A8TA 3BK2A 2BFLA 5AYAA 4EFZA 5HH6A 1VGNA 4D1TA 2BG8A 1Y44A 3DHAA 4Z5ZA 1M2XA 3IOFA 1A7TA 3RKJA 2NZFA 5AHOA 5FQAA 3JXPA 2OHIA 3X2XA 4EYBA 3ZR9A 2BG6A 4RM5A 2OHHA 2ZO4A 3AJ3A 3H3EA 5A0TA 4FSBA 3I11A 4BZ3A 5AJLA 5A23A 2WYMA 3SPUA 1SMLA 4HL2A 5KIKA 5AEBA 5HIQA 4O98A 4EXYA 1JJEA 4UWPB 2FHXB 2BIBA 2ZWRA 5ACQA 2YNVB 5K4KA 5ACSA 5LS3A 4AD9A 1BC2A 5LM6A 1ZKPA 5K0WA 5ACUA 3DH8A 3BC2A 3SD9A 5LMCA 4XWTA 4C1DA 1MQOA 1BVTA 3I14A
chains in the Genus database with same CATH topology
3ESHA 2Y8AA 2FU7A 3T3OA 1L9YA 5HISA 3T9MA 5LCHA 5EW0A 3IOGA 2HB9A 4PVTA 4DIKA 3ADRA 3FAIA 4P62A 1YCGA 5EHTA 2I7VA 4UBQA 2NXAA 4D02A 1X8GA 2BG7A 5B15A 4DILA 5ACTA 2VW8A 5ACWA 3TP9A 1DDKA 4AWZA 3S0ZA 3SFPA 3SBLA 1YCFA 5LLDA 1DXKA 2M5CA 3SW3A 3X30A 2QDSA 2Q9UA 2GFKA 2YCBA 3SRXA 3FCZA 2DKFA 2YNTB 4Z6XA 4TZ9A 2Q0JA 2CBNA 1QH3A 2FK6A 2WYMC 4UWSB 2WRSA 4TZEA 3PY6A 4Z60A 3RKKA 2YZ3A 3IE2A 4J5FA 4C1EA 4GYUA 4ZO3A 4D1WA 2UYXA 2ZNBA 1VJNA 3A4YA 3DHBA 2BFZB 4GCWA 4XWWA 1XTOA 2GMNA 1YCHA 4BP0A 2WYLA 4TYTA 2NZEA 5KILA 5FQBA 2QDTA 2YNUA 4EYFA 1DD6A 3AF6A 3Q6VA 3IDZA 4KEQA 4F6ZA 2BGAA 4H0DA 4J5HA 5LSCA 2XF4A 1X8HA 5FQCA 2P1EA 1WUOA 4D1UA 3X2ZA 3IE0A 2BMIA 5LCAA 4EXSA 2OHJA 2GFJA 4ZNBA 3IELA 1HLKA 2WHGA 4RL0A 5LE1A 5B1UA 5ACPA 3LVZA 4KEPA 1E5DA 3KNSA 3L6NA 3AF5A 2FU6A 3ZQ4A 2I7XA 2P97A 2QJSA 4V0HA 2BG8B 4FEKA 4YSKA 2FHXA 4C1HA 4ZEJA 2YNVA 5EVKA 4AX0B 1WW1A 2XR1A 5ACVA 5A0VA 1JJTA 4YSBA 4YSLA 2A7MA 3R2UA 4Z67A 3T3NA 2FM6A 2FU8A 4FR7A 5HH5A 2GCUA 4C1GA 4HKYA 4RL2A 4UWOB 5K4NA 2BC2A 5B3RA 1KR3A 4EYLA 5HIPA 5EVDA 3KNRA 4RBSA 4Z5YA 4EY2A 3ZWFA 2QINA 4C09A 3P2UA 3QH8A 2Y8BA 1WUPA 3RPCA 4F6HA 3WXCA 5ACXA 2I7TA 3X2YA 3I13A 4U4LA 3IE1A 2P4ZA 1KO2A 1VMEA 5LCFA 4TZBA 1K07A 2H6AA 5EWAA 4C1CA 5EVBA 2P18A 2BR6A 4LE6A 2QEDA 4NQ2A 2Q42A 3G1PA 4NQ6A 1X8IA 2YNWA 2E7YA 1JT1A 5A5ZA 3IEKA 1ZNBA 4CHLA 2FU9A 2YNTA 5IQKA 2Q0IA 1XM8A 3PG4A 4B87A 2BG2A 3F9OA 4PVOA 5EV6A 4AX1B 4UA4A 4C1FA 3I0VA 2R2DA 3DHCA 4RAMA 3ZNBA 2DOOA 2BFZA 2GKLA 1BMCA 3VPEA 2M5DA 4WD6A 5HH4A 4GYQA 3PY5A 4D1VA 4TYFA 2BFKA 2AIOA 1WRAA 4UAMA 5AHRA 3VQZA 4UWRB 5EH9A 1KO3A 4XUKA 4NQ5A 5HIOA 2Y87A 4AWYB 1P9EA 3KL7A 5K4MA 3I15A 5AXRA 4JO0A 3BV6A 4Z7RA 3BK1A 1QH5A 5EV8A 5A87A 5DPXA 3MD7A 5AXOA 4RAWA 4NQ4A 4TZFA 1ZTCA 3IEMA 4ZO2A 2AZ4A 5ACRA 2BTNA 4HL1A 2NYPA 2ZZIA 1A8TA 3BK2A 2BFLA 5AYAA 4EFZA 5HH6A 1VGNA 4D1TA 2BG8A 1Y44A 3DHAA 4Z5ZA 1M2XA 3IOFA 1A7TA 3RKJA 2NZFA 5AHOA 5FQAA 3JXPA 2OHIA 3X2XA 4EYBA 3ZR9A 2BG6A 4RM5A 2OHHA 2ZO4A 3AJ3A 3H3EA 5A0TA 4FSBA 3I11A 4BZ3A 2WYMA 3SPUA 1SMLA 4HL2A 5KIKA 5AEBA 5HIQA 4O98A 4EXYA 1JJEA 4UWPB 2FHXB 2BIBA 2ZWRA 5ACQA 2YNVB 5K4KA 5ACSA 5LS3A 4AD9A 1BC2A 5LM6A 1ZKPA 5K0WA 5ACUA 3DH8A 3BC2A 3SD9A 5LMCA 4XWTA 4C1DA 1MQOA 1BVTA 3I14A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ESH A;  2Y8A A;  2FU7 A;  3T3O A;  1L9Y A;  5HIS A;  3T9M A;  5LCH A;  5EW0 A;  3IOG A;  2HB9 A;  4PVT A;  4DIK A;  3ADR A;  3FAI A;  4P62 A;  1YCG A;  5EHT A;  2I7V A;  4UBQ A;  2NXA A;  4D02 A;  1X8G A;  2BG7 A;  5B15 A;  4DIL A;  5ACT A;  2VW8 A;  5ACW A;  3TP9 A;  1DDK A;  4AWZ A;  3S0Z A;  3SFP A;  3SBL A;  1YCF A;  5LLD A;  1DXK A;  2M5C A;  3SW3 A;  3X30 A;  2QDS A;  2Q9U A;  2GFK A;  2YCB A;  3SRX A;  3FCZ A;  2DKF A;  2YNT B;  4Z6X A;  4TZ9 A;  2Q0J A;  2CBN A;  1QH3 A;  2FK6 A;  2WYM C;  4UWS B;  2WRS A;  4TZE A;  3PY6 A;  4Z60 A;  3RKK A;  2YZ3 A;  3IE2 A;  4J5F A;  4C1E A;  4GYU A;  4ZO3 A;  4D1W A;  2UYX A;  2ZNB A;  1VJN A;  3A4Y A;  3DHB A;  2BFZ B;  4GCW A;  4XWW A;  1XTO A;  2GMN A;  1YCH A;  4BP0 A;  2WYL A;  4TYT A;  2NZE A;  5KIL A;  5FQB A;  2QDT A;  2YNU A;  4EYF A;  1DD6 A;  3AF6 A;  3Q6V A;  3IDZ A;  4KEQ A;  4F6Z A;  2BGA A;  4H0D A;  4J5H A;  5LSC A;  2XF4 A;  1X8H A;  5FQC A;  2P1E A;  1WUO A;  4D1U A;  3X2Z A;  3IE0 A;  2BMI A;  5LCA A;  4EXS A;  2OHJ A;  2GFJ A;  4ZNB A;  3IEL A;  1HLK A;  2WHG A;  4RL0 A;  5LE1 A;  5B1U A;  5ACP A;  3LVZ A;  4KEP A;  1E5D A;  3KNS A;  3L6N A;  3AF5 A;  2FU6 A;  3ZQ4 A;  2I7X A;  2P97 A;  2QJS A;  4V0H A;  2BG8 B;  4FEK A;  4YSK A;  2FHX A;  4C1H A;  4ZEJ A;  2YNV A;  5EVK A;  4AX0 B;  1WW1 A;  2XR1 A;  5ACV A;  5A0V A;  1JJT A;  4YSB A;  4YSL A;  2A7M A;  3R2U A;  4Z67 A;  3T3N A;  2FM6 A;  2FU8 A;  4FR7 A;  5HH5 A;  2GCU A;  4C1G A;  4HKY A;  4RL2 A;  4UWO B;  5K4N A;  2BC2 A;  5B3R A;  1KR3 A;  4EYL A;  5HIP A;  5EVD A;  3KNR A;  4RBS A;  4Z5Y A;  4EY2 A;  3ZWF A;  2QIN A;  4C09 A;  3P2U A;  3QH8 A;  2Y8B A;  1WUP A;  3RPC A;  4F6H A;  3WXC A;  5ACX A;  2I7T A;  3X2Y A;  3I13 A;  4U4L A;  3IE1 A;  2P4Z A;  1KO2 A;  1VME A;  5LCF A;  4TZB A;  1K07 A;  2H6A A;  5EWA A;  4C1C A;  5EVB A;  2P18 A;  2BR6 A;  4LE6 A;  2QED A;  4NQ2 A;  2Q42 A;  3G1P A;  4NQ6 A;  1X8I A;  2YNW A;  2E7Y A;  1JT1 A;  5A5Z A;  3IEK A;  1ZNB A;  4CHL A;  2FU9 A;  2YNT A;  5IQK A;  2Q0I A;  1XM8 A;  3PG4 A;  4B87 A;  2BG2 A;  3F9O A;  4PVO A;  5EV6 A;  4AX1 B;  4UA4 A;  4C1F A;  3I0V A;  2R2D A;  3DHC A;  4RAM A;  3ZNB A;  2DOO A;  2BFZ A;  2GKL A;  1BMC A;  3VPE A;  2M5D A;  4WD6 A;  5HH4 A;  4GYQ A;  3PY5 A;  4D1V A;  4TYF A;  2BFK A;  2AIO A;  1WRA A;  4UAM A;  5AHR A;  3VQZ A;  4UWR B;  5EH9 A;  1KO3 A;  4XUK A;  4NQ5 A;  5HIO A;  2Y87 A;  4AWY B;  1P9E A;  3KL7 A;  5K4M A;  3I15 A;  5AXR A;  4JO0 A;  3BV6 A;  4Z7R A;  3BK1 A;  1QH5 A;  5EV8 A;  5A87 A;  5DPX A;  3MD7 A;  5AXO A;  4RAW A;  4NQ4 A;  4TZF A;  1ZTC A;  3IEM A;  4ZO2 A;  2AZ4 A;  5ACR A;  2BTN A;  4HL1 A;  2NYP A;  2ZZI A;  1A8T A;  3BK2 A;  2BFL A;  5AYA A;  4EFZ A;  5HH6 A;  1VGN A;  4D1T A;  2BG8 A;  1Y44 A;  3DHA A;  4Z5Z A;  1M2X A;  3IOF A;  1A7T A;  3RKJ A;  2NZF A;  5AHO A;  5FQA A;  3JXP A;  2OHI A;  3X2X A;  4EYB A;  3ZR9 A;  2BG6 A;  4RM5 A;  2OHH A;  2ZO4 A;  3AJ3 A;  3H3E A;  5A0T A;  4FSB A;  3I11 A;  4BZ3 A;  2WYM A;  3SPU A;  1SML A;  4HL2 A;  5KIK A;  5AEB A;  5HIQ A;  4O98 A;  4EXY A;  1JJE A;  4UWP B;  2FHX B;  2BIB A;  2ZWR A;  5ACQ A;  2YNV B;  5K4K A;  5ACS A;  5LS3 A;  4AD9 A;  1BC2 A;  5LM6 A;  1ZKP A;  5K0W A;  5ACU A;  3DH8 A;  3BC2 A;  3SD9 A;  5LMC A;  4XWT A;  4C1D A;  1MQO A;  1BVT A;  3I14 A; 
#chains in the Genus database with same CATH topology
 3ESH A;  2Y8A A;  2FU7 A;  3T3O A;  1L9Y A;  5HIS A;  3T9M A;  5LCH A;  5EW0 A;  3IOG A;  2HB9 A;  4PVT A;  4DIK A;  3ADR A;  5AIJ A;  3FAI A;  4P62 A;  1YCG A;  5EHT A;  2I7V A;  4UBQ A;  2NXA A;  4D02 A;  1X8G A;  2CG2 A;  2BG7 A;  5B15 A;  4DIL A;  5ACT A;  2VW8 A;  5ACW A;  3TP9 A;  1DDK A;  4AXH A;  4AWZ A;  3S0Z A;  3SFP A;  3SBL A;  1YCF A;  5LLD A;  1DXK A;  2M5C A;  3SW3 A;  3X30 A;  2QDS A;  2Q9U A;  2GFK A;  2YCB A;  3SRX A;  3FCZ A;  2DKF A;  2YNT B;  4Z6X A;  4TZ9 A;  2Q0J A;  2CBN A;  1QH3 A;  2FK6 A;  2WYM C;  4UWS B;  2WRS A;  4TZE A;  3PY6 A;  4Z60 A;  3RKK A;  2YZ3 A;  3IE2 A;  4J5F A;  4C1E A;  4GYU A;  2CG3 A;  4ZO3 A;  4D1W A;  2UYX A;  2ZNB A;  1VJN A;  3A4Y A;  3DHB A;  2BFZ B;  4GCW A;  4XWW A;  1XTO A;  2GMN A;  1YCH A;  4BP0 A;  4PDX A;  2WYL A;  4TYT A;  2NZE A;  5KIL A;  5FQB A;  2QDT A;  2YNU A;  4EYF A;  1DD6 A;  3AF6 A;  3Q6V A;  3IDZ A;  4KEQ A;  4F6Z A;  2BGA A;  4H0D A;  4J5H A;  5LSC A;  2XF4 A;  1X8H A;  5FQC A;  2P1E A;  1WUO A;  4D1U A;  3X2Z A;  3IE0 A;  2BMI A;  5LCA A;  4EXS A;  2OHJ A;  2GFJ A;  4ZNB A;  3IEL A;  1HLK A;  2WHG A;  4RL0 A;  5LE1 A;  5B1U A;  5ACP A;  3LVZ A;  4KEP A;  1E5D A;  3KNS A;  3L6N A;  3AF5 A;  2FU6 A;  3ZQ4 A;  2I7X A;  2P97 A;  2QJS A;  4V0H A;  2BG8 B;  4FEK A;  4YSK A;  2FHX A;  4C1H A;  4ZEJ A;  2YNV A;  4AV7 A;  5EVK A;  4AX0 B;  1WW1 A;  2XR1 A;  5ACV A;  5A0V A;  1JJT A;  4YSB A;  4YSL A;  2A7M A;  3R2U A;  4Z67 A;  3T3N A;  4NUR A;  2FM6 A;  2FU8 A;  4FR7 A;  5HH5 A;  2GCU A;  4C1G A;  4HKY A;  4RL2 A;  4UWO B;  5K4N A;  2BC2 A;  5B3R A;  1KR3 A;  4EYL A;  5HIP A;  5EVD A;  3KNR A;  4RBS A;  4Z5Y A;  4EY2 A;  3ZWF A;  2QIN A;  4C09 A;  3P2U A;  3QH8 A;  2Y8B A;  1WUP A;  3RPC A;  4F6H A;  3WXC A;  5ACX A;  2I7T A;  3X2Y A;  3I13 A;  4U4L A;  3IE1 A;  2P4Z A;  1KO2 A;  1VME A;  5LCF A;  4TZB A;  1K07 A;  2H6A A;  5EWA A;  4C1C A;  5EVB A;  2P18 A;  2BR6 A;  4LE6 A;  2QED A;  4NQ2 A;  2Q42 A;  3G1P A;  4NQ6 A;  1X8I A;  2YNW A;  2E7Y A;  1JT1 A;  5A5Z A;  3IEK A;  1ZNB A;  4CHL A;  2FU9 A;  2YNT A;  5IQK A;  2Q0I A;  1XM8 A;  3PG4 A;  4B87 A;  2BG2 A;  3F9O A;  4PVO A;  5EV6 A;  4AX1 B;  4UA4 A;  4C1F A;  2CFZ A;  3I0V A;  2R2D A;  2YHE A;  3DHC A;  4RAM A;  3ZNB A;  2DOO A;  2BFZ A;  2GKL A;  1BMC A;  3VPE A;  2M5D A;  4WD6 A;  5HH4 A;  4GYQ A;  3PY5 A;  4D1V A;  4TYF A;  2BFK A;  2AIO A;  1WRA A;  4UAM A;  5AHR A;  3VQZ A;  4UWR B;  5EH9 A;  1KO3 A;  4XUK A;  4NQ5 A;  5HIO A;  2Y87 A;  4AWY B;  1P9E A;  3KL7 A;  5K4M A;  3I15 A;  5AXR A;  4JO0 A;  3BV6 A;  4Z7R A;  3BK1 A;  1QH5 A;  5EV8 A;  5A87 A;  5DPX A;  3MD7 A;  5AXO A;  4RAW A;  4NQ4 A;  4TZF A;  1ZTC A;  3IEM A;  2CFU A;  4ZO2 A;  2AZ4 A;  5ACR A;  2BTN A;  4HL1 A;  2NYP A;  2ZZI A;  1A8T A;  3BK2 A;  2BFL A;  5AYA A;  4EFZ A;  5HH6 A;  1VGN A;  4D1T A;  2BG8 A;  1Y44 A;  3DHA A;  4Z5Z A;  1M2X A;  3IOF A;  1A7T A;  3RKJ A;  2NZF A;  5AHO A;  5FQA A;  3JXP A;  2OHI A;  3X2X A;  4EYB A;  3ZR9 A;  2BG6 A;  4RM5 A;  2OHH A;  2ZO4 A;  3AJ3 A;  3H3E A;  5A0T A;  4FSB A;  3I11 A;  4BZ3 A;  5AJL A;  5A23 A;  2WYM A;  3SPU A;  1SML A;  4HL2 A;  5KIK A;  5AEB A;  5HIQ A;  4O98 A;  4EXY A;  1JJE A;  4UWP B;  2FHX B;  2BIB A;  2ZWR A;  5ACQ A;  2YNV B;  5K4K A;  5ACS A;  5LS3 A;  4AD9 A;  1BC2 A;  5LM6 A;  1ZKP A;  5K0W A;  5ACU A;  3DH8 A;  3BC2 A;  3SD9 A;  5LMC A;  4XWT A;  4C1D A;  1MQO A;  1BVT A;  3I14 A; 
#chains in the Genus database with same CATH homology
 3ESH A;  2Y8A A;  2FU7 A;  3T3O A;  1L9Y A;  5HIS A;  3T9M A;  5LCH A;  5EW0 A;  3IOG A;  2HB9 A;  4PVT A;  4DIK A;  3ADR A;  3FAI A;  4P62 A;  1YCG A;  5EHT A;  2I7V A;  4UBQ A;  2NXA A;  4D02 A;  1X8G A;  2BG7 A;  5B15 A;  4DIL A;  5ACT A;  2VW8 A;  5ACW A;  3TP9 A;  1DDK A;  4AWZ A;  3S0Z A;  3SFP A;  3SBL A;  1YCF A;  5LLD A;  1DXK A;  2M5C A;  3SW3 A;  3X30 A;  2QDS A;  2Q9U A;  2GFK A;  2YCB A;  3SRX A;  3FCZ A;  2DKF A;  2YNT B;  4Z6X A;  4TZ9 A;  2Q0J A;  2CBN A;  1QH3 A;  2FK6 A;  2WYM C;  4UWS B;  2WRS A;  4TZE A;  3PY6 A;  4Z60 A;  3RKK A;  2YZ3 A;  3IE2 A;  4J5F A;  4C1E A;  4GYU A;  4ZO3 A;  4D1W A;  2UYX A;  2ZNB A;  1VJN A;  3A4Y A;  3DHB A;  2BFZ B;  4GCW A;  4XWW A;  1XTO A;  2GMN A;  1YCH A;  4BP0 A;  2WYL A;  4TYT A;  2NZE A;  5KIL A;  5FQB A;  2QDT A;  2YNU A;  4EYF A;  1DD6 A;  3AF6 A;  3Q6V A;  3IDZ A;  4KEQ A;  4F6Z A;  2BGA A;  4H0D A;  4J5H A;  5LSC A;  2XF4 A;  1X8H A;  5FQC A;  2P1E A;  1WUO A;  4D1U A;  3X2Z A;  3IE0 A;  2BMI A;  5LCA A;  4EXS A;  2OHJ A;  2GFJ A;  4ZNB A;  3IEL A;  1HLK A;  2WHG A;  4RL0 A;  5LE1 A;  5B1U A;  5ACP A;  3LVZ A;  4KEP A;  1E5D A;  3KNS A;  3L6N A;  3AF5 A;  2FU6 A;  3ZQ4 A;  2I7X A;  2P97 A;  2QJS A;  4V0H A;  2BG8 B;  4FEK A;  4YSK A;  2FHX A;  4C1H A;  4ZEJ A;  2YNV A;  5EVK A;  4AX0 B;  1WW1 A;  2XR1 A;  5ACV A;  5A0V A;  1JJT A;  4YSB A;  4YSL A;  2A7M A;  3R2U A;  4Z67 A;  3T3N A;  2FM6 A;  2FU8 A;  4FR7 A;  5HH5 A;  2GCU A;  4C1G A;  4HKY A;  4RL2 A;  4UWO B;  5K4N A;  2BC2 A;  5B3R A;  1KR3 A;  4EYL A;  5HIP A;  5EVD A;  3KNR A;  4RBS A;  4Z5Y A;  4EY2 A;  3ZWF A;  2QIN A;  4C09 A;  3P2U A;  3QH8 A;  2Y8B A;  1WUP A;  3RPC A;  4F6H A;  3WXC A;  5ACX A;  2I7T A;  3X2Y A;  3I13 A;  4U4L A;  3IE1 A;  2P4Z A;  1KO2 A;  1VME A;  5LCF A;  4TZB A;  1K07 A;  2H6A A;  5EWA A;  4C1C A;  5EVB A;  2P18 A;  2BR6 A;  4LE6 A;  2QED A;  4NQ2 A;  2Q42 A;  3G1P A;  4NQ6 A;  1X8I A;  2YNW A;  2E7Y A;  1JT1 A;  5A5Z A;  3IEK A;  1ZNB A;  4CHL A;  2FU9 A;  2YNT A;  5IQK A;  2Q0I A;  1XM8 A;  3PG4 A;  4B87 A;  2BG2 A;  3F9O A;  4PVO A;  5EV6 A;  4AX1 B;  4UA4 A;  4C1F A;  3I0V A;  2R2D A;  3DHC A;  4RAM A;  3ZNB A;  2DOO A;  2BFZ A;  2GKL A;  1BMC A;  3VPE A;  2M5D A;  4WD6 A;  5HH4 A;  4GYQ A;  3PY5 A;  4D1V A;  4TYF A;  2BFK A;  2AIO A;  1WRA A;  4UAM A;  5AHR A;  3VQZ A;  4UWR B;  5EH9 A;  1KO3 A;  4XUK A;  4NQ5 A;  5HIO A;  2Y87 A;  4AWY B;  1P9E A;  3KL7 A;  5K4M A;  3I15 A;  5AXR A;  4JO0 A;  3BV6 A;  4Z7R A;  3BK1 A;  1QH5 A;  5EV8 A;  5A87 A;  5DPX A;  3MD7 A;  5AXO A;  4RAW A;  4NQ4 A;  4TZF A;  1ZTC A;  3IEM A;  4ZO2 A;  2AZ4 A;  5ACR A;  2BTN A;  4HL1 A;  2NYP A;  2ZZI A;  1A8T A;  3BK2 A;  2BFL A;  5AYA A;  4EFZ A;  5HH6 A;  1VGN A;  4D1T A;  2BG8 A;  1Y44 A;  3DHA A;  4Z5Z A;  1M2X A;  3IOF A;  1A7T A;  3RKJ A;  2NZF A;  5AHO A;  5FQA A;  3JXP A;  2OHI A;  3X2X A;  4EYB A;  3ZR9 A;  2BG6 A;  4RM5 A;  2OHH A;  2ZO4 A;  3AJ3 A;  3H3E A;  5A0T A;  4FSB A;  3I11 A;  4BZ3 A;  2WYM A;  3SPU A;  1SML A;  4HL2 A;  5KIK A;  5AEB A;  5HIQ A;  4O98 A;  4EXY A;  1JJE A;  4UWP B;  2FHX B;  2BIB A;  2ZWR A;  5ACQ A;  2YNV B;  5K4K A;  5ACS A;  5LS3 A;  4AD9 A;  1BC2 A;  5LM6 A;  1ZKP A;  5K0W A;  5ACU A;  3DH8 A;  3BC2 A;  3SD9 A;  5LMC A;  4XWT A;  4C1D A;  1MQO A;  1BVT A;  3I14 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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