4RM5A

Structural and mechanistic insights into ndm-1 catalyzed hydrolysis of cephalosporins
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
230
structure length
226
Chain Sequence
TGDQRFGDLVFRQLAPNVWQHTSYLDMAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTHAHQNKMGGMDALHAAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and Mechanistic Insights into NDM-1 Catalyzed Hydrolysis of Cephalosporins.
pubmed doi rcsb
source organism Klebsiella pneumoniae
molecule tags Hydrolase
molecule keywords Beta-lactamase NDM-1
total genus 74
structure length 226
sequence length 230
chains with identical sequence B, C, D
ec nomenclature ec 3.5.2.6: Beta-lactamase.
pdb deposition date 2014-10-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 4rm5A00
2VW8A 2BMIA 3T9MA 1YCGA 2BTNA 3PG4A 1A8TA 4F6HA 1ZKPA 3JXPA 4FSBA 4EXSA 3AF6A 5FQCA 2Y8BA 3I14A 2YNWA 2QINA 4NQ4A 2YNUA 3IDZA 2FHXB 5EW0A 5ACRA 5HH6A 4D1VA 4XUKA 2BR6A 3S0ZA 4FR7A 2I7XA 2YNTA 2I7TA 5KIKA 1YCHA 3SD9A 3FAIA 4ZEJA 3I0VA 5LCHA 5ACPA 2P18A 2NYPA 1ZTCA 4PVOA 2QJSA 1JJEA 2GCUA 2WRSA 5DPXA 1XM8A 4XWWA 5LMCA 4TZFA 2ZO4A 4GCWA 3VQZA 4C1CA 3G1PA 4TYFA 1JJTA 2FU6A 3ADRA 4NQ6A 2FHXA 3PY5A 2FU9A 3DHBA 4UWOB 3ESHA 1QH3A 4KEQA 2Q0IA 2Q0JA 4B87A 4BP0A 5AXRA 4RBSA 2BG2A 2BC2A 1HLKA 3VPEA 4WD6A 2GFKA 5EVBA 3L6NA 4TYTA 1YCFA 4TZ9A 1BVTA 5HIQA 4C1EA 4P62A 4XWTA 5ACSA 4O98A 2CBNA 5LE1A 4ZNBA 2QEDA 5ACXA 3WXCA 5EVKA 2BGAA 2R2DA 3KNRA 4EFZA 3IE0A 1X8GA 2GKLA 3PY6A 5EV8A 5A87A 5EHTA 1DD6A 3IOGA 2BG6A 4Z6XA 2P97A 5EH9A 2P1EA 2OHIA 2NZEA 2I7VA 4EXYA 4HKYA 2A7MA 5ACVA 4UWRB 3IE2A 3DHCA 5HISA 4CHLA 1BMCA 3DHAA 1Y44A 1WRAA 4C1GA 2QDSA 3RPCA 4JO0A 4UWSB 3ZR9A 2Y87A 5LSCA 3FCZA 2NXAA 2ZZIA 1SMLA 3BK2A 5K4NA 2FM6A 1WUPA 4D1TA 1WW1A 5K0WA 5A5ZA 2WYMC 2ZWRA 4EYBA 1ZNBA 5HH4A 2BFLA 2WHGA 5LCFA 4EYLA 2M5DA 4EY2A 3ZQ4A 2BG7A 2WYMA 4Z67A 5FQAA 5AXOA 3H3EA 4Z5YA 4Z7RA 5LM6A 4Z60A 2AZ4A 5B3RA 5A0TA 3R2UA 2P4ZA 4UA4A 2BFZB 4AX0B 3QH8A 4RL0A 3I15A 3AJ3A 2NZFA 1DDKA 5B15A 3ZNBA 4RL2A 4TZBA 1VGNA 3I11A 3RKKA 4Z5ZA 5ACUA 2M5CA 4D1UA 1KO2A 5HH5A 2FK6A 3I13A 4UWPB 5FQBA 5K4MA 3RKJA 4ZO3A 4C09A 1VJNA 4NQ5A 4PVTA 5AHRA 3P2UA 1QH5A 4AD9A 5EV6A 4V0HA 2XR1A 5ACWA 4D1WA 5EVDA 5AHOA 2WYLA 1KR3A 3X30A 1X8IA 2YNTB 3SW3A 5HIPA 4RM5A 1JT1A 1DXKA 3BC2A 2YNVB 3MD7A 3IEKA 1VMEA 3SPUA 2E7YA 4F6ZA 3IE1A 5K4KA 5A0VA 2YZ3A 4C1DA 2ZNBA 3SFPA 2FU7A 4BZ3A 1M2XA 1P9EA 4TZEA 4LE6A 5B1UA 4GYUA 4C1FA 4YSBA 3IEMA 5AEBA 3X2XA 5LCAA 5EWAA 2GMNA 4FEKA 5HIOA 4RAMA 3DH8A 1WUOA 3BK1A 4NQ2A 2BG8B 2Y8AA 2OHJA 2BG8A 4H0DA 3A4YA 4DILA 2YNVA 5IQKA 2DOOA 1K07A 4J5HA 3SRXA 1BC2A 4DIKA 2BFZA 2HB9A 5AYAA 2QDTA 2GFJA 3T3OA 2BFKA 4AWYB 2OHHA 4HL1A 1L9YA 3Q6VA 4C1HA 2FU8A 3KNSA 3IELA 4GYQA 5KILA 1MQOA 4EYFA 3LVZA 4U4LA 3IOFA 2UYXA 4YSLA 2YCBA 1KO3A 3T3NA 1E5DA 2XF4A 5LLDA 5LS3A 3TP9A 3X2ZA 1XTOA 4AWZA 5ACTA 2Q9UA 3SBLA 3AF5A 3ZWFA 4UBQA 2Q42A 3BV6A 2DKFA 4KEPA 4RAWA 3F9OA 2AIOA 4HL2A 5ACQA 4AX1B 4YSKA 4UAMA 4D02A 1A7TA 3X2YA 3KL7A 4ZO2A 2BIBA 4J5FA 2H6AA 1X8HA
chains in the Genus database with same CATH superfamily
2VW8A 2BMIA 3T9MA 1YCGA 2BTNA 3PG4A 1A8TA 4F6HA 2CFUA 1ZKPA 3JXPA 4FSBA 4EXSA 3AF6A 5FQCA 2Y8BA 3I14A 2YNWA 2QINA 4NQ4A 2YNUA 3IDZA 2FHXB 5EW0A 5ACRA 5HH6A 4D1VA 4XUKA 2BR6A 3S0ZA 4FR7A 2I7XA 2YNTA 2I7TA 5KIKA 1YCHA 3SD9A 3FAIA 4ZEJA 3I0VA 5LCHA 5ACPA 2P18A 2NYPA 1ZTCA 4PVOA 2QJSA 1JJEA 2GCUA 2WRSA 5DPXA 1XM8A 4XWWA 5LMCA 4TZFA 2ZO4A 4GCWA 3VQZA 4C1CA 3G1PA 4TYFA 1JJTA 2FU6A 3ADRA 4NQ6A 2FHXA 3PY5A 2FU9A 3DHBA 4UWOB 3ESHA 1QH3A 4NURA 4KEQA 2Q0IA 2Q0JA 4B87A 4BP0A 5AXRA 4RBSA 2BG2A 2BC2A 1HLKA 3VPEA 4WD6A 2GFKA 5EVBA 3L6NA 4TYTA 1YCFA 4TZ9A 1BVTA 5HIQA 4C1EA 4P62A 4XWTA 5ACSA 4O98A 2CBNA 5LE1A 4ZNBA 2QEDA 5ACXA 3WXCA 5EVKA 2BGAA 2R2DA 3KNRA 4EFZA 3IE0A 1X8GA 2GKLA 3PY6A 5EV8A 5A87A 5EHTA 1DD6A 3IOGA 2BG6A 5A23A 2CG3A 4Z6XA 2P97A 5EH9A 2P1EA 2OHIA 2NZEA 2I7VA 4EXYA 4HKYA 2A7MA 5ACVA 2CFZA 4UWRB 3IE2A 3DHCA 5HISA 4CHLA 1BMCA 3DHAA 1Y44A 1WRAA 4C1GA 2QDSA 3RPCA 4JO0A 4UWSB 3ZR9A 2Y87A 5LSCA 3FCZA 2NXAA 2ZZIA 1SMLA 3BK2A 5K4NA 2FM6A 1WUPA 4D1TA 1WW1A 5K0WA 5A5ZA 2WYMC 2ZWRA 4EYBA 1ZNBA 5HH4A 2BFLA 2WHGA 5LCFA 4EYLA 2M5DA 4EY2A 3ZQ4A 2BG7A 2WYMA 4Z67A 5FQAA 5AXOA 3H3EA 4Z5YA 4Z7RA 5LM6A 4Z60A 2AZ4A 5B3RA 5A0TA 3R2UA 2P4ZA 4UA4A 2BFZB 4AX0B 3QH8A 4RL0A 4AV7A 3I15A 3AJ3A 2NZFA 1DDKA 5B15A 3ZNBA 4RL2A 4TZBA 1VGNA 3I11A 3RKKA 4Z5ZA 5ACUA 2M5CA 4D1UA 1KO2A 5HH5A 2FK6A 3I13A 4UWPB 5FQBA 5K4MA 3RKJA 4ZO3A 4C09A 1VJNA 4NQ5A 4PVTA 5AHRA 3P2UA 1QH5A 4AD9A 5EV6A 4V0HA 2XR1A 5ACWA 4D1WA 5EVDA 5AHOA 2WYLA 1KR3A 3X30A 4AXHA 1X8IA 2YNTB 3SW3A 5HIPA 4PDXA 4RM5A 1JT1A 1DXKA 3BC2A 2YNVB 3MD7A 3IEKA 1VMEA 3SPUA 2CG2A 2E7YA 4F6ZA 3IE1A 5K4KA 5A0VA 2YZ3A 4C1DA 2ZNBA 3SFPA 2FU7A 4BZ3A 1M2XA 1P9EA 4TZEA 4LE6A 5B1UA 4GYUA 4C1FA 4YSBA 3IEMA 2YHEA 5AEBA 3X2XA 5LCAA 5EWAA 2GMNA 4FEKA 5HIOA 4RAMA 3DH8A 1WUOA 3BK1A 4NQ2A 2BG8B 2Y8AA 2OHJA 2BG8A 4H0DA 3A4YA 4DILA 2YNVA 5IQKA 2DOOA 1K07A 4J5HA 3SRXA 1BC2A 4DIKA 2BFZA 2HB9A 5AYAA 2QDTA 2GFJA 3T3OA 2BFKA 4AWYB 2OHHA 4HL1A 1L9YA 3Q6VA 4C1HA 2FU8A 3KNSA 3IELA 4GYQA 5KILA 1MQOA 4EYFA 3LVZA 4U4LA 3IOFA 2UYXA 4YSLA 2YCBA 1KO3A 3T3NA 1E5DA 2XF4A 5LLDA 5AJLA 5LS3A 3TP9A 3X2ZA 1XTOA 4AWZA 5ACTA 2Q9UA 5AIJA 3SBLA 3AF5A 3ZWFA 4UBQA 2Q42A 3BV6A 2DKFA 4KEPA 4RAWA 3F9OA 2AIOA 4HL2A 5ACQA 4AX1B 4YSKA 4UAMA 4D02A 1A7TA 3X2YA 3KL7A 4ZO2A 2BIBA 4J5FA 2H6AA 1X8HA
chains in the Genus database with same CATH topology
2VW8A 2BMIA 3T9MA 1YCGA 2BTNA 3PG4A 1A8TA 4F6HA 1ZKPA 3JXPA 4FSBA 4EXSA 3AF6A 5FQCA 2Y8BA 3I14A 2YNWA 2QINA 4NQ4A 2YNUA 3IDZA 2FHXB 5EW0A 5ACRA 5HH6A 4D1VA 4XUKA 2BR6A 3S0ZA 4FR7A 2I7XA 2YNTA 2I7TA 5KIKA 1YCHA 3SD9A 3FAIA 4ZEJA 3I0VA 5LCHA 5ACPA 2P18A 2NYPA 1ZTCA 4PVOA 2QJSA 1JJEA 2GCUA 2WRSA 5DPXA 1XM8A 4XWWA 5LMCA 4TZFA 2ZO4A 4GCWA 3VQZA 4C1CA 3G1PA 4TYFA 1JJTA 2FU6A 3ADRA 4NQ6A 2FHXA 3PY5A 2FU9A 3DHBA 4UWOB 3ESHA 1QH3A 4KEQA 2Q0IA 2Q0JA 4B87A 4BP0A 5AXRA 4RBSA 2BG2A 2BC2A 1HLKA 3VPEA 4WD6A 2GFKA 5EVBA 3L6NA 4TYTA 1YCFA 4TZ9A 1BVTA 5HIQA 4C1EA 4P62A 4XWTA 5ACSA 4O98A 2CBNA 5LE1A 4ZNBA 2QEDA 5ACXA 3WXCA 5EVKA 2BGAA 2R2DA 3KNRA 4EFZA 3IE0A 1X8GA 2GKLA 3PY6A 5EV8A 5A87A 5EHTA 1DD6A 3IOGA 2BG6A 4Z6XA 2P97A 5EH9A 2P1EA 2OHIA 2NZEA 2I7VA 4EXYA 4HKYA 2A7MA 5ACVA 4UWRB 3IE2A 3DHCA 5HISA 4CHLA 1BMCA 3DHAA 1Y44A 1WRAA 4C1GA 2QDSA 3RPCA 4JO0A 4UWSB 3ZR9A 2Y87A 5LSCA 3FCZA 2NXAA 2ZZIA 1SMLA 3BK2A 5K4NA 2FM6A 1WUPA 4D1TA 1WW1A 5K0WA 5A5ZA 2WYMC 2ZWRA 4EYBA 1ZNBA 5HH4A 2BFLA 2WHGA 5LCFA 4EYLA 2M5DA 4EY2A 3ZQ4A 2BG7A 2WYMA 4Z67A 5FQAA 5AXOA 3H3EA 4Z5YA 4Z7RA 5LM6A 4Z60A 2AZ4A 5B3RA 5A0TA 3R2UA 2P4ZA 4UA4A 2BFZB 4AX0B 3QH8A 4RL0A 3I15A 3AJ3A 2NZFA 1DDKA 5B15A 3ZNBA 4RL2A 4TZBA 1VGNA 3I11A 3RKKA 4Z5ZA 5ACUA 2M5CA 4D1UA 1KO2A 5HH5A 2FK6A 3I13A 4UWPB 5FQBA 5K4MA 3RKJA 4ZO3A 4C09A 1VJNA 4NQ5A 4PVTA 5AHRA 3P2UA 1QH5A 4AD9A 5EV6A 4V0HA 2XR1A 5ACWA 4D1WA 5EVDA 5AHOA 2WYLA 1KR3A 3X30A 1X8IA 2YNTB 3SW3A 5HIPA 4RM5A 1JT1A 1DXKA 3BC2A 2YNVB 3MD7A 3IEKA 1VMEA 3SPUA 2E7YA 4F6ZA 3IE1A 5K4KA 5A0VA 2YZ3A 4C1DA 2ZNBA 3SFPA 2FU7A 4BZ3A 1M2XA 1P9EA 4TZEA 4LE6A 5B1UA 4GYUA 4C1FA 4YSBA 3IEMA 5AEBA 3X2XA 5LCAA 5EWAA 2GMNA 4FEKA 5HIOA 4RAMA 3DH8A 1WUOA 3BK1A 4NQ2A 2BG8B 2Y8AA 2OHJA 2BG8A 4H0DA 3A4YA 4DILA 2YNVA 5IQKA 2DOOA 1K07A 4J5HA 3SRXA 1BC2A 4DIKA 2BFZA 2HB9A 5AYAA 2QDTA 2GFJA 3T3OA 2BFKA 4AWYB 2OHHA 4HL1A 1L9YA 3Q6VA 4C1HA 2FU8A 3KNSA 3IELA 4GYQA 5KILA 1MQOA 4EYFA 3LVZA 4U4LA 3IOFA 2UYXA 4YSLA 2YCBA 1KO3A 3T3NA 1E5DA 2XF4A 5LLDA 5LS3A 3TP9A 3X2ZA 1XTOA 4AWZA 5ACTA 2Q9UA 3SBLA 3AF5A 3ZWFA 4UBQA 2Q42A 3BV6A 2DKFA 4KEPA 4RAWA 3F9OA 2AIOA 4HL2A 5ACQA 4AX1B 4YSKA 4UAMA 4D02A 1A7TA 3X2YA 3KL7A 4ZO2A 2BIBA 4J5FA 2H6AA 1X8HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VW8 A;  2BMI A;  3T9M A;  1YCG A;  2BTN A;  3PG4 A;  1A8T A;  4F6H A;  1ZKP A;  3JXP A;  4FSB A;  4EXS A;  3AF6 A;  5FQC A;  2Y8B A;  3I14 A;  2YNW A;  2QIN A;  4NQ4 A;  2YNU A;  3IDZ A;  2FHX B;  5EW0 A;  5ACR A;  5HH6 A;  4D1V A;  4XUK A;  2BR6 A;  3S0Z A;  4FR7 A;  2I7X A;  2YNT A;  2I7T A;  5KIK A;  1YCH A;  3SD9 A;  3FAI A;  4ZEJ A;  3I0V A;  5LCH A;  5ACP A;  2P18 A;  2NYP A;  1ZTC A;  4PVO A;  2QJS A;  1JJE A;  2GCU A;  2WRS A;  5DPX A;  1XM8 A;  4XWW A;  5LMC A;  4TZF A;  2ZO4 A;  4GCW A;  3VQZ A;  4C1C A;  3G1P A;  4TYF A;  1JJT A;  2FU6 A;  3ADR A;  4NQ6 A;  2FHX A;  3PY5 A;  2FU9 A;  3DHB A;  4UWO B;  3ESH A;  1QH3 A;  4KEQ A;  2Q0I A;  2Q0J A;  4B87 A;  4BP0 A;  5AXR A;  4RBS A;  2BG2 A;  2BC2 A;  1HLK A;  3VPE A;  4WD6 A;  2GFK A;  5EVB A;  3L6N A;  4TYT A;  1YCF A;  4TZ9 A;  1BVT A;  5HIQ A;  4C1E A;  4P62 A;  4XWT A;  5ACS A;  4O98 A;  2CBN A;  5LE1 A;  4ZNB A;  2QED A;  5ACX A;  3WXC A;  5EVK A;  2BGA A;  2R2D A;  3KNR A;  4EFZ A;  3IE0 A;  1X8G A;  2GKL A;  3PY6 A;  5EV8 A;  5A87 A;  5EHT A;  1DD6 A;  3IOG A;  2BG6 A;  4Z6X A;  2P97 A;  5EH9 A;  2P1E A;  2OHI A;  2NZE A;  2I7V A;  4EXY A;  4HKY A;  2A7M A;  5ACV A;  4UWR B;  3IE2 A;  3DHC A;  5HIS A;  4CHL A;  1BMC A;  3DHA A;  1Y44 A;  1WRA A;  4C1G A;  2QDS A;  3RPC A;  4JO0 A;  4UWS B;  3ZR9 A;  2Y87 A;  5LSC A;  3FCZ A;  2NXA A;  2ZZI A;  1SML A;  3BK2 A;  5K4N A;  2FM6 A;  1WUP A;  4D1T A;  1WW1 A;  5K0W A;  5A5Z A;  2WYM C;  2ZWR A;  4EYB A;  1ZNB A;  5HH4 A;  2BFL A;  2WHG A;  5LCF A;  4EYL A;  2M5D A;  4EY2 A;  3ZQ4 A;  2BG7 A;  2WYM A;  4Z67 A;  5FQA A;  5AXO A;  3H3E A;  4Z5Y A;  4Z7R A;  5LM6 A;  4Z60 A;  2AZ4 A;  5B3R A;  5A0T A;  3R2U A;  2P4Z A;  4UA4 A;  2BFZ B;  4AX0 B;  3QH8 A;  4RL0 A;  3I15 A;  3AJ3 A;  2NZF A;  1DDK A;  5B15 A;  3ZNB A;  4RL2 A;  4TZB A;  1VGN A;  3I11 A;  3RKK A;  4Z5Z A;  5ACU A;  2M5C A;  4D1U A;  1KO2 A;  5HH5 A;  2FK6 A;  3I13 A;  4UWP B;  5FQB A;  5K4M A;  3RKJ A;  4ZO3 A;  4C09 A;  1VJN A;  4NQ5 A;  4PVT A;  5AHR A;  3P2U A;  1QH5 A;  4AD9 A;  5EV6 A;  4V0H A;  2XR1 A;  5ACW A;  4D1W A;  5EVD A;  5AHO A;  2WYL A;  1KR3 A;  3X30 A;  1X8I A;  2YNT B;  3SW3 A;  5HIP A;  4RM5 A;  1JT1 A;  1DXK A;  3BC2 A;  2YNV B;  3MD7 A;  3IEK A;  1VME A;  3SPU A;  2E7Y A;  4F6Z A;  3IE1 A;  5K4K A;  5A0V A;  2YZ3 A;  4C1D A;  2ZNB A;  3SFP A;  2FU7 A;  4BZ3 A;  1M2X A;  1P9E A;  4TZE A;  4LE6 A;  5B1U A;  4GYU A;  4C1F A;  4YSB A;  3IEM A;  5AEB A;  3X2X A;  5LCA A;  5EWA A;  2GMN A;  4FEK A;  5HIO A;  4RAM A;  3DH8 A;  1WUO A;  3BK1 A;  4NQ2 A;  2BG8 B;  2Y8A A;  2OHJ A;  2BG8 A;  4H0D A;  3A4Y A;  4DIL A;  2YNV A;  5IQK A;  2DOO A;  1K07 A;  4J5H A;  3SRX A;  1BC2 A;  4DIK A;  2BFZ A;  2HB9 A;  5AYA A;  2QDT A;  2GFJ A;  3T3O A;  2BFK A;  4AWY B;  2OHH A;  4HL1 A;  1L9Y A;  3Q6V A;  4C1H A;  2FU8 A;  3KNS A;  3IEL A;  4GYQ A;  5KIL A;  1MQO A;  4EYF A;  3LVZ A;  4U4L A;  3IOF A;  2UYX A;  4YSL A;  2YCB A;  1KO3 A;  3T3N A;  1E5D A;  2XF4 A;  5LLD A;  5LS3 A;  3TP9 A;  3X2Z A;  1XTO A;  4AWZ A;  5ACT A;  2Q9U A;  3SBL A;  3AF5 A;  3ZWF A;  4UBQ A;  2Q42 A;  3BV6 A;  2DKF A;  4KEP A;  4RAW A;  3F9O A;  2AIO A;  4HL2 A;  5ACQ A;  4AX1 B;  4YSK A;  4UAM A;  4D02 A;  1A7T A;  3X2Y A;  3KL7 A;  4ZO2 A;  2BIB A;  4J5F A;  2H6A A;  1X8H A; 
#chains in the Genus database with same CATH topology
 2VW8 A;  2BMI A;  3T9M A;  1YCG A;  2BTN A;  3PG4 A;  1A8T A;  4F6H A;  2CFU A;  1ZKP A;  3JXP A;  4FSB A;  4EXS A;  3AF6 A;  5FQC A;  2Y8B A;  3I14 A;  2YNW A;  2QIN A;  4NQ4 A;  2YNU A;  3IDZ A;  2FHX B;  5EW0 A;  5ACR A;  5HH6 A;  4D1V A;  4XUK A;  2BR6 A;  3S0Z A;  4FR7 A;  2I7X A;  2YNT A;  2I7T A;  5KIK A;  1YCH A;  3SD9 A;  3FAI A;  4ZEJ A;  3I0V A;  5LCH A;  5ACP A;  2P18 A;  2NYP A;  1ZTC A;  4PVO A;  2QJS A;  1JJE A;  2GCU A;  2WRS A;  5DPX A;  1XM8 A;  4XWW A;  5LMC A;  4TZF A;  2ZO4 A;  4GCW A;  3VQZ A;  4C1C A;  3G1P A;  4TYF A;  1JJT A;  2FU6 A;  3ADR A;  4NQ6 A;  2FHX A;  3PY5 A;  2FU9 A;  3DHB A;  4UWO B;  3ESH A;  1QH3 A;  4NUR A;  4KEQ A;  2Q0I A;  2Q0J A;  4B87 A;  4BP0 A;  5AXR A;  4RBS A;  2BG2 A;  2BC2 A;  1HLK A;  3VPE A;  4WD6 A;  2GFK A;  5EVB A;  3L6N A;  4TYT A;  1YCF A;  4TZ9 A;  1BVT A;  5HIQ A;  4C1E A;  4P62 A;  4XWT A;  5ACS A;  4O98 A;  2CBN A;  5LE1 A;  4ZNB A;  2QED A;  5ACX A;  3WXC A;  5EVK A;  2BGA A;  2R2D A;  3KNR A;  4EFZ A;  3IE0 A;  1X8G A;  2GKL A;  3PY6 A;  5EV8 A;  5A87 A;  5EHT A;  1DD6 A;  3IOG A;  2BG6 A;  5A23 A;  2CG3 A;  4Z6X A;  2P97 A;  5EH9 A;  2P1E A;  2OHI A;  2NZE A;  2I7V A;  4EXY A;  4HKY A;  2A7M A;  5ACV A;  2CFZ A;  4UWR B;  3IE2 A;  3DHC A;  5HIS A;  4CHL A;  1BMC A;  3DHA A;  1Y44 A;  1WRA A;  4C1G A;  2QDS A;  3RPC A;  4JO0 A;  4UWS B;  3ZR9 A;  2Y87 A;  5LSC A;  3FCZ A;  2NXA A;  2ZZI A;  1SML A;  3BK2 A;  5K4N A;  2FM6 A;  1WUP A;  4D1T A;  1WW1 A;  5K0W A;  5A5Z A;  2WYM C;  2ZWR A;  4EYB A;  1ZNB A;  5HH4 A;  2BFL A;  2WHG A;  5LCF A;  4EYL A;  2M5D A;  4EY2 A;  3ZQ4 A;  2BG7 A;  2WYM A;  4Z67 A;  5FQA A;  5AXO A;  3H3E A;  4Z5Y A;  4Z7R A;  5LM6 A;  4Z60 A;  2AZ4 A;  5B3R A;  5A0T A;  3R2U A;  2P4Z A;  4UA4 A;  2BFZ B;  4AX0 B;  3QH8 A;  4RL0 A;  4AV7 A;  3I15 A;  3AJ3 A;  2NZF A;  1DDK A;  5B15 A;  3ZNB A;  4RL2 A;  4TZB A;  1VGN A;  3I11 A;  3RKK A;  4Z5Z A;  5ACU A;  2M5C A;  4D1U A;  1KO2 A;  5HH5 A;  2FK6 A;  3I13 A;  4UWP B;  5FQB A;  5K4M A;  3RKJ A;  4ZO3 A;  4C09 A;  1VJN A;  4NQ5 A;  4PVT A;  5AHR A;  3P2U A;  1QH5 A;  4AD9 A;  5EV6 A;  4V0H A;  2XR1 A;  5ACW A;  4D1W A;  5EVD A;  5AHO A;  2WYL A;  1KR3 A;  3X30 A;  4AXH A;  1X8I A;  2YNT B;  3SW3 A;  5HIP A;  4PDX A;  4RM5 A;  1JT1 A;  1DXK A;  3BC2 A;  2YNV B;  3MD7 A;  3IEK A;  1VME A;  3SPU A;  2CG2 A;  2E7Y A;  4F6Z A;  3IE1 A;  5K4K A;  5A0V A;  2YZ3 A;  4C1D A;  2ZNB A;  3SFP A;  2FU7 A;  4BZ3 A;  1M2X A;  1P9E A;  4TZE A;  4LE6 A;  5B1U A;  4GYU A;  4C1F A;  4YSB A;  3IEM A;  2YHE A;  5AEB A;  3X2X A;  5LCA A;  5EWA A;  2GMN A;  4FEK A;  5HIO A;  4RAM A;  3DH8 A;  1WUO A;  3BK1 A;  4NQ2 A;  2BG8 B;  2Y8A A;  2OHJ A;  2BG8 A;  4H0D A;  3A4Y A;  4DIL A;  2YNV A;  5IQK A;  2DOO A;  1K07 A;  4J5H A;  3SRX A;  1BC2 A;  4DIK A;  2BFZ A;  2HB9 A;  5AYA A;  2QDT A;  2GFJ A;  3T3O A;  2BFK A;  4AWY B;  2OHH A;  4HL1 A;  1L9Y A;  3Q6V A;  4C1H A;  2FU8 A;  3KNS A;  3IEL A;  4GYQ A;  5KIL A;  1MQO A;  4EYF A;  3LVZ A;  4U4L A;  3IOF A;  2UYX A;  4YSL A;  2YCB A;  1KO3 A;  3T3N A;  1E5D A;  2XF4 A;  5LLD A;  5AJL A;  5LS3 A;  3TP9 A;  3X2Z A;  1XTO A;  4AWZ A;  5ACT A;  2Q9U A;  5AIJ A;  3SBL A;  3AF5 A;  3ZWF A;  4UBQ A;  2Q42 A;  3BV6 A;  2DKF A;  4KEP A;  4RAW A;  3F9O A;  2AIO A;  4HL2 A;  5ACQ A;  4AX1 B;  4YSK A;  4UAM A;  4D02 A;  1A7T A;  3X2Y A;  3KL7 A;  4ZO2 A;  2BIB A;  4J5F A;  2H6A A;  1X8H A; 
#chains in the Genus database with same CATH homology
 2VW8 A;  2BMI A;  3T9M A;  1YCG A;  2BTN A;  3PG4 A;  1A8T A;  4F6H A;  1ZKP A;  3JXP A;  4FSB A;  4EXS A;  3AF6 A;  5FQC A;  2Y8B A;  3I14 A;  2YNW A;  2QIN A;  4NQ4 A;  2YNU A;  3IDZ A;  2FHX B;  5EW0 A;  5ACR A;  5HH6 A;  4D1V A;  4XUK A;  2BR6 A;  3S0Z A;  4FR7 A;  2I7X A;  2YNT A;  2I7T A;  5KIK A;  1YCH A;  3SD9 A;  3FAI A;  4ZEJ A;  3I0V A;  5LCH A;  5ACP A;  2P18 A;  2NYP A;  1ZTC A;  4PVO A;  2QJS A;  1JJE A;  2GCU A;  2WRS A;  5DPX A;  1XM8 A;  4XWW A;  5LMC A;  4TZF A;  2ZO4 A;  4GCW A;  3VQZ A;  4C1C A;  3G1P A;  4TYF A;  1JJT A;  2FU6 A;  3ADR A;  4NQ6 A;  2FHX A;  3PY5 A;  2FU9 A;  3DHB A;  4UWO B;  3ESH A;  1QH3 A;  4KEQ A;  2Q0I A;  2Q0J A;  4B87 A;  4BP0 A;  5AXR A;  4RBS A;  2BG2 A;  2BC2 A;  1HLK A;  3VPE A;  4WD6 A;  2GFK A;  5EVB A;  3L6N A;  4TYT A;  1YCF A;  4TZ9 A;  1BVT A;  5HIQ A;  4C1E A;  4P62 A;  4XWT A;  5ACS A;  4O98 A;  2CBN A;  5LE1 A;  4ZNB A;  2QED A;  5ACX A;  3WXC A;  5EVK A;  2BGA A;  2R2D A;  3KNR A;  4EFZ A;  3IE0 A;  1X8G A;  2GKL A;  3PY6 A;  5EV8 A;  5A87 A;  5EHT A;  1DD6 A;  3IOG A;  2BG6 A;  4Z6X A;  2P97 A;  5EH9 A;  2P1E A;  2OHI A;  2NZE A;  2I7V A;  4EXY A;  4HKY A;  2A7M A;  5ACV A;  4UWR B;  3IE2 A;  3DHC A;  5HIS A;  4CHL A;  1BMC A;  3DHA A;  1Y44 A;  1WRA A;  4C1G A;  2QDS A;  3RPC A;  4JO0 A;  4UWS B;  3ZR9 A;  2Y87 A;  5LSC A;  3FCZ A;  2NXA A;  2ZZI A;  1SML A;  3BK2 A;  5K4N A;  2FM6 A;  1WUP A;  4D1T A;  1WW1 A;  5K0W A;  5A5Z A;  2WYM C;  2ZWR A;  4EYB A;  1ZNB A;  5HH4 A;  2BFL A;  2WHG A;  5LCF A;  4EYL A;  2M5D A;  4EY2 A;  3ZQ4 A;  2BG7 A;  2WYM A;  4Z67 A;  5FQA A;  5AXO A;  3H3E A;  4Z5Y A;  4Z7R A;  5LM6 A;  4Z60 A;  2AZ4 A;  5B3R A;  5A0T A;  3R2U A;  2P4Z A;  4UA4 A;  2BFZ B;  4AX0 B;  3QH8 A;  4RL0 A;  3I15 A;  3AJ3 A;  2NZF A;  1DDK A;  5B15 A;  3ZNB A;  4RL2 A;  4TZB A;  1VGN A;  3I11 A;  3RKK A;  4Z5Z A;  5ACU A;  2M5C A;  4D1U A;  1KO2 A;  5HH5 A;  2FK6 A;  3I13 A;  4UWP B;  5FQB A;  5K4M A;  3RKJ A;  4ZO3 A;  4C09 A;  1VJN A;  4NQ5 A;  4PVT A;  5AHR A;  3P2U A;  1QH5 A;  4AD9 A;  5EV6 A;  4V0H A;  2XR1 A;  5ACW A;  4D1W A;  5EVD A;  5AHO A;  2WYL A;  1KR3 A;  3X30 A;  1X8I A;  2YNT B;  3SW3 A;  5HIP A;  4RM5 A;  1JT1 A;  1DXK A;  3BC2 A;  2YNV B;  3MD7 A;  3IEK A;  1VME A;  3SPU A;  2E7Y A;  4F6Z A;  3IE1 A;  5K4K A;  5A0V A;  2YZ3 A;  4C1D A;  2ZNB A;  3SFP A;  2FU7 A;  4BZ3 A;  1M2X A;  1P9E A;  4TZE A;  4LE6 A;  5B1U A;  4GYU A;  4C1F A;  4YSB A;  3IEM A;  5AEB A;  3X2X A;  5LCA A;  5EWA A;  2GMN A;  4FEK A;  5HIO A;  4RAM A;  3DH8 A;  1WUO A;  3BK1 A;  4NQ2 A;  2BG8 B;  2Y8A A;  2OHJ A;  2BG8 A;  4H0D A;  3A4Y A;  4DIL A;  2YNV A;  5IQK A;  2DOO A;  1K07 A;  4J5H A;  3SRX A;  1BC2 A;  4DIK A;  2BFZ A;  2HB9 A;  5AYA A;  2QDT A;  2GFJ A;  3T3O A;  2BFK A;  4AWY B;  2OHH A;  4HL1 A;  1L9Y A;  3Q6V A;  4C1H A;  2FU8 A;  3KNS A;  3IEL A;  4GYQ A;  5KIL A;  1MQO A;  4EYF A;  3LVZ A;  4U4L A;  3IOF A;  2UYX A;  4YSL A;  2YCB A;  1KO3 A;  3T3N A;  1E5D A;  2XF4 A;  5LLD A;  5LS3 A;  3TP9 A;  3X2Z A;  1XTO A;  4AWZ A;  5ACT A;  2Q9U A;  3SBL A;  3AF5 A;  3ZWF A;  4UBQ A;  2Q42 A;  3BV6 A;  2DKF A;  4KEP A;  4RAW A;  3F9O A;  2AIO A;  4HL2 A;  5ACQ A;  4AX1 B;  4YSK A;  4UAM A;  4D02 A;  1A7T A;  3X2Y A;  3KL7 A;  4ZO2 A;  2BIB A;  4J5F A;  2H6A A;  1X8H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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