1HLKA

Metallo-beta-lactamase from bacteroides fragilis in complex with a tricyclic inhibitor
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
227
structure length
227
Chain Sequence
SVKISDDISITQLSDKVYTYVSLAEIEGWGMVPSNGMIVINNHQAALLDTPINDAQTEMLVNWVTDSLHAKVTTFIPNHWHGDCIGGLGYLQRKGVQSYANQMTIDLAKEKGLPVPEHGFTDSLTVSLDGMPLQCYYLGGGHATDNIVVWLPTENILFGGCMLKDNQATSIGNISDADVTAWPKTLDKVKAKFPSARYVVPGHGDYGGTELIEHTKQIVNQYIESTS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification of a series of tricyclic natural products as potent broad spectrum inhibitors of metallo-beta-lactamases
pubmed doi rcsb
molecule tags Hydrolase
source organism Bacteroides fragilis
molecule keywords BETA-LACTAMASE, TYPE II
total genus 67
structure length 227
sequence length 227
chains with identical sequence B
ec nomenclature ec 3.5.2.6: Beta-lactamase.
pdb deposition date 2000-12-01
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 1hlkA00
5LM6A 3I15A 3ESHA 2QEDA 2I7VA 4C1CA 5HISA 2M5CA 3SBLA 1WUPA 2NYPA 1XM8A 5HIPA 2BFZB 2WHGA 5ACSA 3I11A 1WUOA 4C1FA 4AWYB 1E5DA 2HB9A 5LS3A 3Q6VA 3ZR9A 1A7TA 2VW8A 4D02A 3RKJA 4UWSB 4TZ9A 2DOOA 3L6NA 5KILA 4C1EA 5AEBA 4NQ2A 4HKYA 1M2XA 4LE6A 2BG8B 4D1TA 3S0ZA 3SPUA 2QDTA 3F9OA 4ZEJA 5EV8A 1Y44A 3R2UA 4O98A 5AXRA 5DPXA 2BG7A 4WD6A 4AX0B 4XWWA 2QDSA 4BP0A 5EWAA 4HL2A 4C1GA 2WYMA 3PG4A 1VMEA 2BIBA 3KL7A 2Y8AA 4EXSA 5EW0A 2ZWRA 3VPEA 2BFLA 5LLDA 3IEMA 4DILA 4YSKA 3SRXA 2XF4A 2GFKA 1JJTA 3IDZA 5HH5A 4CHLA 1SMLA 2QJSA 3H3EA 2GCUA 2BG2A 2AZ4A 2GFJA 4EXYA 3RKKA 4ZO2A 5ACRA 4V0HA 4PVOA 2WRSA 3AF5A 5K0WA 3T3OA 1YCFA 3IE2A 4Z7RA 5EH9A 4GYQA 2ZO4A 4C1DA 4FSBA 4GCWA 2NZFA 5KIKA 4AD9A 2I7TA 3ADRA 2FHXA 3DH8A 5AHRA 2YNVA 3T9MA 4C09A 3FAIA 5HIQA 1QH5A 3SFPA 5EVDA 4HL1A 1KO3A 4J5FA 1ZKPA 1ZNBA 2BFZA 2BGAA 1HLKA 2ZZIA 3LVZA 3BK1A 4NQ5A 5ACQA 1ZTCA 1L9YA 4Z60A 3FCZA 2Q0IA 4D1UA 2FU8A 1KR3A 2YNTA 3IEKA 3BV6A 5IQKA 3DHCA 3DHAA 2FU9A 1A8TA 4UA4A 1YCHA 3QH8A 4UWOB 2BR6A 3AF6A 2BG8A 3ZNBA 5LCFA 4TZEA 4D1WA 2UYXA 3PY6A 3JXPA 3MD7A 3IE1A 3DHBA 1YCGA 1JT1A 2Q42A 2ZNBA 3IE0A 1QH3A 2BG6A 3IELA 4AWZA 4RBSA 5LE1A 4EYLA 1WRAA 4YSLA 5K4KA 4RAWA 3RPCA 2FK6A 2WYLA 1DXKA 5FQAA 1X8IA 4Z5ZA 3WXCA 2FM6A 3BK2A 5B1UA 1WW1A 5LCHA 5EHTA 2YNWA 5ACWA 4C1HA 4UBQA 4UWPB 2P4ZA 4UWRB 3VQZA 3SW3A 2AIOA 1KO2A 2P18A 2BFKA 2YCBA 4TYTA 1VGNA 5B3RA 2M5DA 2WYMC 4H0DA 4Z67A 2YNVB 1DDKA 1X8GA 1BVTA 4EYFA 4FR7A 4RM5A 2QINA 2NXAA 2GMNA 3T3NA 3X2YA 3I0VA 2I7XA 3I13A 5A0TA 2OHHA 4RL0A 5A87A 1VJNA 3X2XA 3SD9A 5AYAA 2CBNA 2OHJA 5HIOA 4EY2A 2BMIA 1BC2A 4XWTA 2P97A 4TYFA 1MQOA 5A5ZA 4EFZA 5A0VA 4GYUA 4DIKA 3KNRA 2A7MA 4F6HA 4XUKA 1DD6A 4RAMA 4D1VA 3IOFA 2YNTB 2FU6A 4AX1B 2Q9UA 4BZ3A 4KEQA 2P1EA 2BTNA 5EVBA 2FU7A 2H6AA 3BC2A 4ZO3A 4F6ZA 3KNSA 4NQ4A 5ACVA 4TZBA 1X8HA 1XTOA 3I14A 4J5HA 1K07A 5ACUA 3ZWFA 2DKFA 5EVKA 4PVTA 4Z6XA 5ACPA 5LCAA 2GKLA 3PY5A 5FQBA 3X30A 4B87A 4NQ6A 5B15A 4Z5YA 3A4YA 5HH4A 3IOGA 4FEKA 4RL2A 4JO0A 5FQCA 5ACXA 3X2ZA 2YNUA 5EV6A 1P9EA 2OHIA 2Q0JA 5K4NA 5LSCA 4U4LA 2YZ3A 2Y87A 4ZNBA 4EYBA 2Y8BA 5HH6A 4TZFA 4UAMA 4P62A 3G1PA 5ACTA 2E7YA 2FHXB 5AXOA 5LMCA 3TP9A 2XR1A 4YSBA 2R2DA 2BC2A 1BMCA 5K4MA 5AHOA 3AJ3A 2NZEA 3ZQ4A 3P2UA 1JJEA 4KEPA
chains in the Genus database with same CATH superfamily
5LM6A 3I15A 3ESHA 2QEDA 2I7VA 4C1CA 5HISA 2M5CA 3SBLA 1WUPA 2NYPA 1XM8A 5HIPA 2BFZB 2WHGA 5ACSA 3I11A 1WUOA 4C1FA 4AWYB 1E5DA 2HB9A 5LS3A 3Q6VA 3ZR9A 1A7TA 2VW8A 4D02A 3RKJA 2CG2A 4UWSB 4TZ9A 5A23A 2DOOA 3L6NA 5KILA 4C1EA 5AEBA 4NQ2A 4HKYA 1M2XA 4LE6A 2BG8B 4D1TA 3S0ZA 3SPUA 2QDTA 3F9OA 4ZEJA 5EV8A 1Y44A 3R2UA 4O98A 5AXRA 5DPXA 2BG7A 4WD6A 4AX0B 4XWWA 2QDSA 4BP0A 5EWAA 4HL2A 4C1GA 2WYMA 3PG4A 1VMEA 2BIBA 3KL7A 2Y8AA 4EXSA 5EW0A 2ZWRA 3VPEA 2BFLA 5LLDA 3IEMA 4DILA 4YSKA 3SRXA 2XF4A 2GFKA 1JJTA 3IDZA 5HH5A 4CHLA 1SMLA 2QJSA 3H3EA 2GCUA 2BG2A 2AZ4A 2GFJA 4EXYA 3RKKA 4ZO2A 5ACRA 4V0HA 4PVOA 2WRSA 3AF5A 5K0WA 3T3OA 1YCFA 3IE2A 4Z7RA 5EH9A 4GYQA 2ZO4A 4AXHA 4C1DA 4FSBA 4GCWA 2NZFA 5KIKA 4AD9A 2I7TA 3ADRA 2FHXA 3DH8A 5AHRA 2YNVA 3T9MA 4C09A 3FAIA 5HIQA 1QH5A 3SFPA 5EVDA 4HL1A 1KO3A 4AV7A 4J5FA 1ZKPA 2CG3A 1ZNBA 2BFZA 2BGAA 1HLKA 2ZZIA 3LVZA 3BK1A 4NQ5A 5ACQA 1ZTCA 1L9YA 4Z60A 3FCZA 2Q0IA 4D1UA 2FU8A 1KR3A 2YNTA 3IEKA 3BV6A 5IQKA 3DHCA 3DHAA 2FU9A 1A8TA 4UA4A 1YCHA 3QH8A 4UWOB 2BR6A 3AF6A 2BG8A 3ZNBA 5LCFA 4TZEA 4D1WA 2UYXA 3PY6A 3JXPA 3MD7A 3IE1A 3DHBA 1YCGA 1JT1A 2Q42A 2ZNBA 3IE0A 1QH3A 2BG6A 3IELA 4AWZA 4RBSA 5LE1A 4EYLA 1WRAA 4YSLA 5K4KA 4NURA 4RAWA 3RPCA 2FK6A 2CFZA 2WYLA 1DXKA 5AIJA 5FQAA 1X8IA 4Z5ZA 3WXCA 2FM6A 3BK2A 5B1UA 1WW1A 5LCHA 4PDXA 5EHTA 2YNWA 5ACWA 4C1HA 4UBQA 4UWPB 2P4ZA 4UWRB 3VQZA 3SW3A 2AIOA 1KO2A 2P18A 2BFKA 2YCBA 4TYTA 1VGNA 5B3RA 2M5DA 2WYMC 4H0DA 4Z67A 2YNVB 1DDKA 1X8GA 1BVTA 4EYFA 4FR7A 4RM5A 2QINA 2NXAA 2GMNA 3T3NA 3X2YA 3I0VA 2I7XA 3I13A 5A0TA 2OHHA 4RL0A 5A87A 1VJNA 3X2XA 3SD9A 5AJLA 5AYAA 2CBNA 2OHJA 5HIOA 4EY2A 2BMIA 1BC2A 4XWTA 2P97A 4TYFA 1MQOA 5A5ZA 4EFZA 5A0VA 4GYUA 4DIKA 3KNRA 2A7MA 4F6HA 4XUKA 1DD6A 4RAMA 4D1VA 3IOFA 2YNTB 2FU6A 4AX1B 2Q9UA 4BZ3A 4KEQA 2P1EA 2BTNA 5EVBA 2FU7A 2H6AA 3BC2A 4ZO3A 2YHEA 4F6ZA 3KNSA 4NQ4A 5ACVA 4TZBA 1X8HA 1XTOA 3I14A 4J5HA 1K07A 5ACUA 3ZWFA 2DKFA 5EVKA 4PVTA 4Z6XA 5ACPA 5LCAA 2GKLA 3PY5A 5FQBA 3X30A 4B87A 4NQ6A 5B15A 4Z5YA 3A4YA 5HH4A 3IOGA 4FEKA 4RL2A 4JO0A 5FQCA 5ACXA 3X2ZA 2YNUA 5EV6A 1P9EA 2OHIA 2Q0JA 5K4NA 5LSCA 4U4LA 2YZ3A 2Y87A 4ZNBA 4EYBA 2Y8BA 5HH6A 4TZFA 4UAMA 4P62A 3G1PA 5ACTA 2E7YA 2FHXB 5AXOA 5LMCA 3TP9A 2XR1A 4YSBA 2R2DA 2BC2A 1BMCA 5K4MA 5AHOA 2CFUA 3AJ3A 2NZEA 3ZQ4A 3P2UA 1JJEA 4KEPA
chains in the Genus database with same CATH topology
5LM6A 3I15A 3ESHA 2QEDA 2I7VA 4C1CA 5HISA 2M5CA 3SBLA 1WUPA 2NYPA 1XM8A 5HIPA 2BFZB 2WHGA 5ACSA 3I11A 1WUOA 4C1FA 4AWYB 1E5DA 2HB9A 5LS3A 3Q6VA 3ZR9A 1A7TA 2VW8A 4D02A 3RKJA 4UWSB 4TZ9A 2DOOA 3L6NA 5KILA 4C1EA 5AEBA 4NQ2A 4HKYA 1M2XA 4LE6A 2BG8B 4D1TA 3S0ZA 3SPUA 2QDTA 3F9OA 4ZEJA 5EV8A 1Y44A 3R2UA 4O98A 5AXRA 5DPXA 2BG7A 4WD6A 4AX0B 4XWWA 2QDSA 4BP0A 5EWAA 4HL2A 4C1GA 2WYMA 3PG4A 1VMEA 2BIBA 3KL7A 2Y8AA 4EXSA 5EW0A 2ZWRA 3VPEA 2BFLA 5LLDA 3IEMA 4DILA 4YSKA 3SRXA 2XF4A 2GFKA 1JJTA 3IDZA 5HH5A 4CHLA 1SMLA 2QJSA 3H3EA 2GCUA 2BG2A 2AZ4A 2GFJA 4EXYA 3RKKA 4ZO2A 5ACRA 4V0HA 4PVOA 2WRSA 3AF5A 5K0WA 3T3OA 1YCFA 3IE2A 4Z7RA 5EH9A 4GYQA 2ZO4A 4C1DA 4FSBA 4GCWA 2NZFA 5KIKA 4AD9A 2I7TA 3ADRA 2FHXA 3DH8A 5AHRA 2YNVA 3T9MA 4C09A 3FAIA 5HIQA 1QH5A 3SFPA 5EVDA 4HL1A 1KO3A 4J5FA 1ZKPA 1ZNBA 2BFZA 2BGAA 1HLKA 2ZZIA 3LVZA 3BK1A 4NQ5A 5ACQA 1ZTCA 1L9YA 4Z60A 3FCZA 2Q0IA 4D1UA 2FU8A 1KR3A 2YNTA 3IEKA 3BV6A 5IQKA 3DHCA 3DHAA 2FU9A 1A8TA 4UA4A 1YCHA 3QH8A 4UWOB 2BR6A 3AF6A 2BG8A 3ZNBA 5LCFA 4TZEA 4D1WA 2UYXA 3PY6A 3JXPA 3MD7A 3IE1A 3DHBA 1YCGA 1JT1A 2Q42A 2ZNBA 3IE0A 1QH3A 2BG6A 3IELA 4AWZA 4RBSA 5LE1A 4EYLA 1WRAA 4YSLA 5K4KA 4RAWA 3RPCA 2FK6A 2WYLA 1DXKA 5FQAA 1X8IA 4Z5ZA 3WXCA 2FM6A 3BK2A 5B1UA 1WW1A 5LCHA 5EHTA 2YNWA 5ACWA 4C1HA 4UBQA 4UWPB 2P4ZA 4UWRB 3VQZA 3SW3A 2AIOA 1KO2A 2P18A 2BFKA 2YCBA 4TYTA 1VGNA 5B3RA 2M5DA 2WYMC 4H0DA 4Z67A 2YNVB 1DDKA 1X8GA 1BVTA 4EYFA 4FR7A 4RM5A 2QINA 2NXAA 2GMNA 3T3NA 3X2YA 3I0VA 2I7XA 3I13A 5A0TA 2OHHA 4RL0A 5A87A 1VJNA 3X2XA 3SD9A 5AYAA 2CBNA 2OHJA 5HIOA 4EY2A 2BMIA 1BC2A 4XWTA 2P97A 4TYFA 1MQOA 5A5ZA 4EFZA 5A0VA 4GYUA 4DIKA 3KNRA 2A7MA 4F6HA 4XUKA 1DD6A 4RAMA 4D1VA 3IOFA 2YNTB 2FU6A 4AX1B 2Q9UA 4BZ3A 4KEQA 2P1EA 2BTNA 5EVBA 2FU7A 2H6AA 3BC2A 4ZO3A 4F6ZA 3KNSA 4NQ4A 5ACVA 4TZBA 1X8HA 1XTOA 3I14A 4J5HA 1K07A 5ACUA 3ZWFA 2DKFA 5EVKA 4PVTA 4Z6XA 5ACPA 5LCAA 2GKLA 3PY5A 5FQBA 3X30A 4B87A 4NQ6A 5B15A 4Z5YA 3A4YA 5HH4A 3IOGA 4FEKA 4RL2A 4JO0A 5FQCA 5ACXA 3X2ZA 2YNUA 5EV6A 1P9EA 2OHIA 2Q0JA 5K4NA 5LSCA 4U4LA 2YZ3A 2Y87A 4ZNBA 4EYBA 2Y8BA 5HH6A 4TZFA 4UAMA 4P62A 3G1PA 5ACTA 2E7YA 2FHXB 5AXOA 5LMCA 3TP9A 2XR1A 4YSBA 2R2DA 2BC2A 1BMCA 5K4MA 5AHOA 3AJ3A 2NZEA 3ZQ4A 3P2UA 1JJEA 4KEPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5LM6 A;  3I15 A;  3ESH A;  2QED A;  2I7V A;  4C1C A;  5HIS A;  2M5C A;  3SBL A;  1WUP A;  2NYP A;  1XM8 A;  5HIP A;  2BFZ B;  2WHG A;  5ACS A;  3I11 A;  1WUO A;  4C1F A;  4AWY B;  1E5D A;  2HB9 A;  5LS3 A;  3Q6V A;  3ZR9 A;  1A7T A;  2VW8 A;  4D02 A;  3RKJ A;  4UWS B;  4TZ9 A;  2DOO A;  3L6N A;  5KIL A;  4C1E A;  5AEB A;  4NQ2 A;  4HKY A;  1M2X A;  4LE6 A;  2BG8 B;  4D1T A;  3S0Z A;  3SPU A;  2QDT A;  3F9O A;  4ZEJ A;  5EV8 A;  1Y44 A;  3R2U A;  4O98 A;  5AXR A;  5DPX A;  2BG7 A;  4WD6 A;  4AX0 B;  4XWW A;  2QDS A;  4BP0 A;  5EWA A;  4HL2 A;  4C1G A;  2WYM A;  3PG4 A;  1VME A;  2BIB A;  3KL7 A;  2Y8A A;  4EXS A;  5EW0 A;  2ZWR A;  3VPE A;  2BFL A;  5LLD A;  3IEM A;  4DIL A;  4YSK A;  3SRX A;  2XF4 A;  2GFK A;  1JJT A;  3IDZ A;  5HH5 A;  4CHL A;  1SML A;  2QJS A;  3H3E A;  2GCU A;  2BG2 A;  2AZ4 A;  2GFJ A;  4EXY A;  3RKK A;  4ZO2 A;  5ACR A;  4V0H A;  4PVO A;  2WRS A;  3AF5 A;  5K0W A;  3T3O A;  1YCF A;  3IE2 A;  4Z7R A;  5EH9 A;  4GYQ A;  2ZO4 A;  4C1D A;  4FSB A;  4GCW A;  2NZF A;  5KIK A;  4AD9 A;  2I7T A;  3ADR A;  2FHX A;  3DH8 A;  5AHR A;  2YNV A;  3T9M A;  4C09 A;  3FAI A;  5HIQ A;  1QH5 A;  3SFP A;  5EVD A;  4HL1 A;  1KO3 A;  4J5F A;  1ZKP A;  1ZNB A;  2BFZ A;  2BGA A;  1HLK A;  2ZZI A;  3LVZ A;  3BK1 A;  4NQ5 A;  5ACQ A;  1ZTC A;  1L9Y A;  4Z60 A;  3FCZ A;  2Q0I A;  4D1U A;  2FU8 A;  1KR3 A;  2YNT A;  3IEK A;  3BV6 A;  5IQK A;  3DHC A;  3DHA A;  2FU9 A;  1A8T A;  4UA4 A;  1YCH A;  3QH8 A;  4UWO B;  2BR6 A;  3AF6 A;  2BG8 A;  3ZNB A;  5LCF A;  4TZE A;  4D1W A;  2UYX A;  3PY6 A;  3JXP A;  3MD7 A;  3IE1 A;  3DHB A;  1YCG A;  1JT1 A;  2Q42 A;  2ZNB A;  3IE0 A;  1QH3 A;  2BG6 A;  3IEL A;  4AWZ A;  4RBS A;  5LE1 A;  4EYL A;  1WRA A;  4YSL A;  5K4K A;  4RAW A;  3RPC A;  2FK6 A;  2WYL A;  1DXK A;  5FQA A;  1X8I A;  4Z5Z A;  3WXC A;  2FM6 A;  3BK2 A;  5B1U A;  1WW1 A;  5LCH A;  5EHT A;  2YNW A;  5ACW A;  4C1H A;  4UBQ A;  4UWP B;  2P4Z A;  4UWR B;  3VQZ A;  3SW3 A;  2AIO A;  1KO2 A;  2P18 A;  2BFK A;  2YCB A;  4TYT A;  1VGN A;  5B3R A;  2M5D A;  2WYM C;  4H0D A;  4Z67 A;  2YNV B;  1DDK A;  1X8G A;  1BVT A;  4EYF A;  4FR7 A;  4RM5 A;  2QIN A;  2NXA A;  2GMN A;  3T3N A;  3X2Y A;  3I0V A;  2I7X A;  3I13 A;  5A0T A;  2OHH A;  4RL0 A;  5A87 A;  1VJN A;  3X2X A;  3SD9 A;  5AYA A;  2CBN A;  2OHJ A;  5HIO A;  4EY2 A;  2BMI A;  1BC2 A;  4XWT A;  2P97 A;  4TYF A;  1MQO A;  5A5Z A;  4EFZ A;  5A0V A;  4GYU A;  4DIK A;  3KNR A;  2A7M A;  4F6H A;  4XUK A;  1DD6 A;  4RAM A;  4D1V A;  3IOF A;  2YNT B;  2FU6 A;  4AX1 B;  2Q9U A;  4BZ3 A;  4KEQ A;  2P1E A;  2BTN A;  5EVB A;  2FU7 A;  2H6A A;  3BC2 A;  4ZO3 A;  4F6Z A;  3KNS A;  4NQ4 A;  5ACV A;  4TZB A;  1X8H A;  1XTO A;  3I14 A;  4J5H A;  1K07 A;  5ACU A;  3ZWF A;  2DKF A;  5EVK A;  4PVT A;  4Z6X A;  5ACP A;  5LCA A;  2GKL A;  3PY5 A;  5FQB A;  3X30 A;  4B87 A;  4NQ6 A;  5B15 A;  4Z5Y A;  3A4Y A;  5HH4 A;  3IOG A;  4FEK A;  4RL2 A;  4JO0 A;  5FQC A;  5ACX A;  3X2Z A;  2YNU A;  5EV6 A;  1P9E A;  2OHI A;  2Q0J A;  5K4N A;  5LSC A;  4U4L A;  2YZ3 A;  2Y87 A;  4ZNB A;  4EYB A;  2Y8B A;  5HH6 A;  4TZF A;  4UAM A;  4P62 A;  3G1P A;  5ACT A;  2E7Y A;  2FHX B;  5AXO A;  5LMC A;  3TP9 A;  2XR1 A;  4YSB A;  2R2D A;  2BC2 A;  1BMC A;  5K4M A;  5AHO A;  3AJ3 A;  2NZE A;  3ZQ4 A;  3P2U A;  1JJE A;  4KEP A; 
#chains in the Genus database with same CATH topology
 5LM6 A;  3I15 A;  3ESH A;  2QED A;  2I7V A;  4C1C A;  5HIS A;  2M5C A;  3SBL A;  1WUP A;  2NYP A;  1XM8 A;  5HIP A;  2BFZ B;  2WHG A;  5ACS A;  3I11 A;  1WUO A;  4C1F A;  4AWY B;  1E5D A;  2HB9 A;  5LS3 A;  3Q6V A;  3ZR9 A;  1A7T A;  2VW8 A;  4D02 A;  3RKJ A;  2CG2 A;  4UWS B;  4TZ9 A;  5A23 A;  2DOO A;  3L6N A;  5KIL A;  4C1E A;  5AEB A;  4NQ2 A;  4HKY A;  1M2X A;  4LE6 A;  2BG8 B;  4D1T A;  3S0Z A;  3SPU A;  2QDT A;  3F9O A;  4ZEJ A;  5EV8 A;  1Y44 A;  3R2U A;  4O98 A;  5AXR A;  5DPX A;  2BG7 A;  4WD6 A;  4AX0 B;  4XWW A;  2QDS A;  4BP0 A;  5EWA A;  4HL2 A;  4C1G A;  2WYM A;  3PG4 A;  1VME A;  2BIB A;  3KL7 A;  2Y8A A;  4EXS A;  5EW0 A;  2ZWR A;  3VPE A;  2BFL A;  5LLD A;  3IEM A;  4DIL A;  4YSK A;  3SRX A;  2XF4 A;  2GFK A;  1JJT A;  3IDZ A;  5HH5 A;  4CHL A;  1SML A;  2QJS A;  3H3E A;  2GCU A;  2BG2 A;  2AZ4 A;  2GFJ A;  4EXY A;  3RKK A;  4ZO2 A;  5ACR A;  4V0H A;  4PVO A;  2WRS A;  3AF5 A;  5K0W A;  3T3O A;  1YCF A;  3IE2 A;  4Z7R A;  5EH9 A;  4GYQ A;  2ZO4 A;  4AXH A;  4C1D A;  4FSB A;  4GCW A;  2NZF A;  5KIK A;  4AD9 A;  2I7T A;  3ADR A;  2FHX A;  3DH8 A;  5AHR A;  2YNV A;  3T9M A;  4C09 A;  3FAI A;  5HIQ A;  1QH5 A;  3SFP A;  5EVD A;  4HL1 A;  1KO3 A;  4AV7 A;  4J5F A;  1ZKP A;  2CG3 A;  1ZNB A;  2BFZ A;  2BGA A;  1HLK A;  2ZZI A;  3LVZ A;  3BK1 A;  4NQ5 A;  5ACQ A;  1ZTC A;  1L9Y A;  4Z60 A;  3FCZ A;  2Q0I A;  4D1U A;  2FU8 A;  1KR3 A;  2YNT A;  3IEK A;  3BV6 A;  5IQK A;  3DHC A;  3DHA A;  2FU9 A;  1A8T A;  4UA4 A;  1YCH A;  3QH8 A;  4UWO B;  2BR6 A;  3AF6 A;  2BG8 A;  3ZNB A;  5LCF A;  4TZE A;  4D1W A;  2UYX A;  3PY6 A;  3JXP A;  3MD7 A;  3IE1 A;  3DHB A;  1YCG A;  1JT1 A;  2Q42 A;  2ZNB A;  3IE0 A;  1QH3 A;  2BG6 A;  3IEL A;  4AWZ A;  4RBS A;  5LE1 A;  4EYL A;  1WRA A;  4YSL A;  5K4K A;  4NUR A;  4RAW A;  3RPC A;  2FK6 A;  2CFZ A;  2WYL A;  1DXK A;  5AIJ A;  5FQA A;  1X8I A;  4Z5Z A;  3WXC A;  2FM6 A;  3BK2 A;  5B1U A;  1WW1 A;  5LCH A;  4PDX A;  5EHT A;  2YNW A;  5ACW A;  4C1H A;  4UBQ A;  4UWP B;  2P4Z A;  4UWR B;  3VQZ A;  3SW3 A;  2AIO A;  1KO2 A;  2P18 A;  2BFK A;  2YCB A;  4TYT A;  1VGN A;  5B3R A;  2M5D A;  2WYM C;  4H0D A;  4Z67 A;  2YNV B;  1DDK A;  1X8G A;  1BVT A;  4EYF A;  4FR7 A;  4RM5 A;  2QIN A;  2NXA A;  2GMN A;  3T3N A;  3X2Y A;  3I0V A;  2I7X A;  3I13 A;  5A0T A;  2OHH A;  4RL0 A;  5A87 A;  1VJN A;  3X2X A;  3SD9 A;  5AJL A;  5AYA A;  2CBN A;  2OHJ A;  5HIO A;  4EY2 A;  2BMI A;  1BC2 A;  4XWT A;  2P97 A;  4TYF A;  1MQO A;  5A5Z A;  4EFZ A;  5A0V A;  4GYU A;  4DIK A;  3KNR A;  2A7M A;  4F6H A;  4XUK A;  1DD6 A;  4RAM A;  4D1V A;  3IOF A;  2YNT B;  2FU6 A;  4AX1 B;  2Q9U A;  4BZ3 A;  4KEQ A;  2P1E A;  2BTN A;  5EVB A;  2FU7 A;  2H6A A;  3BC2 A;  4ZO3 A;  2YHE A;  4F6Z A;  3KNS A;  4NQ4 A;  5ACV A;  4TZB A;  1X8H A;  1XTO A;  3I14 A;  4J5H A;  1K07 A;  5ACU A;  3ZWF A;  2DKF A;  5EVK A;  4PVT A;  4Z6X A;  5ACP A;  5LCA A;  2GKL A;  3PY5 A;  5FQB A;  3X30 A;  4B87 A;  4NQ6 A;  5B15 A;  4Z5Y A;  3A4Y A;  5HH4 A;  3IOG A;  4FEK A;  4RL2 A;  4JO0 A;  5FQC A;  5ACX A;  3X2Z A;  2YNU A;  5EV6 A;  1P9E A;  2OHI A;  2Q0J A;  5K4N A;  5LSC A;  4U4L A;  2YZ3 A;  2Y87 A;  4ZNB A;  4EYB A;  2Y8B A;  5HH6 A;  4TZF A;  4UAM A;  4P62 A;  3G1P A;  5ACT A;  2E7Y A;  2FHX B;  5AXO A;  5LMC A;  3TP9 A;  2XR1 A;  4YSB A;  2R2D A;  2BC2 A;  1BMC A;  5K4M A;  5AHO A;  2CFU A;  3AJ3 A;  2NZE A;  3ZQ4 A;  3P2U A;  1JJE A;  4KEP A; 
#chains in the Genus database with same CATH homology
 5LM6 A;  3I15 A;  3ESH A;  2QED A;  2I7V A;  4C1C A;  5HIS A;  2M5C A;  3SBL A;  1WUP A;  2NYP A;  1XM8 A;  5HIP A;  2BFZ B;  2WHG A;  5ACS A;  3I11 A;  1WUO A;  4C1F A;  4AWY B;  1E5D A;  2HB9 A;  5LS3 A;  3Q6V A;  3ZR9 A;  1A7T A;  2VW8 A;  4D02 A;  3RKJ A;  4UWS B;  4TZ9 A;  2DOO A;  3L6N A;  5KIL A;  4C1E A;  5AEB A;  4NQ2 A;  4HKY A;  1M2X A;  4LE6 A;  2BG8 B;  4D1T A;  3S0Z A;  3SPU A;  2QDT A;  3F9O A;  4ZEJ A;  5EV8 A;  1Y44 A;  3R2U A;  4O98 A;  5AXR A;  5DPX A;  2BG7 A;  4WD6 A;  4AX0 B;  4XWW A;  2QDS A;  4BP0 A;  5EWA A;  4HL2 A;  4C1G A;  2WYM A;  3PG4 A;  1VME A;  2BIB A;  3KL7 A;  2Y8A A;  4EXS A;  5EW0 A;  2ZWR A;  3VPE A;  2BFL A;  5LLD A;  3IEM A;  4DIL A;  4YSK A;  3SRX A;  2XF4 A;  2GFK A;  1JJT A;  3IDZ A;  5HH5 A;  4CHL A;  1SML A;  2QJS A;  3H3E A;  2GCU A;  2BG2 A;  2AZ4 A;  2GFJ A;  4EXY A;  3RKK A;  4ZO2 A;  5ACR A;  4V0H A;  4PVO A;  2WRS A;  3AF5 A;  5K0W A;  3T3O A;  1YCF A;  3IE2 A;  4Z7R A;  5EH9 A;  4GYQ A;  2ZO4 A;  4C1D A;  4FSB A;  4GCW A;  2NZF A;  5KIK A;  4AD9 A;  2I7T A;  3ADR A;  2FHX A;  3DH8 A;  5AHR A;  2YNV A;  3T9M A;  4C09 A;  3FAI A;  5HIQ A;  1QH5 A;  3SFP A;  5EVD A;  4HL1 A;  1KO3 A;  4J5F A;  1ZKP A;  1ZNB A;  2BFZ A;  2BGA A;  1HLK A;  2ZZI A;  3LVZ A;  3BK1 A;  4NQ5 A;  5ACQ A;  1ZTC A;  1L9Y A;  4Z60 A;  3FCZ A;  2Q0I A;  4D1U A;  2FU8 A;  1KR3 A;  2YNT A;  3IEK A;  3BV6 A;  5IQK A;  3DHC A;  3DHA A;  2FU9 A;  1A8T A;  4UA4 A;  1YCH A;  3QH8 A;  4UWO B;  2BR6 A;  3AF6 A;  2BG8 A;  3ZNB A;  5LCF A;  4TZE A;  4D1W A;  2UYX A;  3PY6 A;  3JXP A;  3MD7 A;  3IE1 A;  3DHB A;  1YCG A;  1JT1 A;  2Q42 A;  2ZNB A;  3IE0 A;  1QH3 A;  2BG6 A;  3IEL A;  4AWZ A;  4RBS A;  5LE1 A;  4EYL A;  1WRA A;  4YSL A;  5K4K A;  4RAW A;  3RPC A;  2FK6 A;  2WYL A;  1DXK A;  5FQA A;  1X8I A;  4Z5Z A;  3WXC A;  2FM6 A;  3BK2 A;  5B1U A;  1WW1 A;  5LCH A;  5EHT A;  2YNW A;  5ACW A;  4C1H A;  4UBQ A;  4UWP B;  2P4Z A;  4UWR B;  3VQZ A;  3SW3 A;  2AIO A;  1KO2 A;  2P18 A;  2BFK A;  2YCB A;  4TYT A;  1VGN A;  5B3R A;  2M5D A;  2WYM C;  4H0D A;  4Z67 A;  2YNV B;  1DDK A;  1X8G A;  1BVT A;  4EYF A;  4FR7 A;  4RM5 A;  2QIN A;  2NXA A;  2GMN A;  3T3N A;  3X2Y A;  3I0V A;  2I7X A;  3I13 A;  5A0T A;  2OHH A;  4RL0 A;  5A87 A;  1VJN A;  3X2X A;  3SD9 A;  5AYA A;  2CBN A;  2OHJ A;  5HIO A;  4EY2 A;  2BMI A;  1BC2 A;  4XWT A;  2P97 A;  4TYF A;  1MQO A;  5A5Z A;  4EFZ A;  5A0V A;  4GYU A;  4DIK A;  3KNR A;  2A7M A;  4F6H A;  4XUK A;  1DD6 A;  4RAM A;  4D1V A;  3IOF A;  2YNT B;  2FU6 A;  4AX1 B;  2Q9U A;  4BZ3 A;  4KEQ A;  2P1E A;  2BTN A;  5EVB A;  2FU7 A;  2H6A A;  3BC2 A;  4ZO3 A;  4F6Z A;  3KNS A;  4NQ4 A;  5ACV A;  4TZB A;  1X8H A;  1XTO A;  3I14 A;  4J5H A;  1K07 A;  5ACU A;  3ZWF A;  2DKF A;  5EVK A;  4PVT A;  4Z6X A;  5ACP A;  5LCA A;  2GKL A;  3PY5 A;  5FQB A;  3X30 A;  4B87 A;  4NQ6 A;  5B15 A;  4Z5Y A;  3A4Y A;  5HH4 A;  3IOG A;  4FEK A;  4RL2 A;  4JO0 A;  5FQC A;  5ACX A;  3X2Z A;  2YNU A;  5EV6 A;  1P9E A;  2OHI A;  2Q0J A;  5K4N A;  5LSC A;  4U4L A;  2YZ3 A;  2Y87 A;  4ZNB A;  4EYB A;  2Y8B A;  5HH6 A;  4TZF A;  4UAM A;  4P62 A;  3G1P A;  5ACT A;  2E7Y A;  2FHX B;  5AXO A;  5LMC A;  3TP9 A;  2XR1 A;  4YSB A;  2R2D A;  2BC2 A;  1BMC A;  5K4M A;  5AHO A;  3AJ3 A;  2NZE A;  3ZQ4 A;  3P2U A;  1JJE A;  4KEP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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