2CM3A

Structure of protein tyrosine phosphatase 1b (c2)
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
274
structure length
274
Chain Sequence
FEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Inhibition of Protein-Tyrosine Phosphatase 1B by Isothiazolidinone Heterocyclic Phosphonate Mimetics.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1
total genus 88
structure length 274
sequence length 274
chains with identical sequence B
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2006-05-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2cm3A00
4NWGA 2PSZA 4GFVA 3V0FA 5EHPA 2F71A 2H4GA 3EU0A 3QCCA 4R30A 1LQFA 2CM2A 2PQ5A 1Q6TA 1PYNA 2PI7A 1Q6SA 2CM8A 1WAXA 1KAVA 2C7SA 1ZC0A 2Y96A 1OETA 1FQ1A 4Y14A 2PT0A 1QXKA 4ICZA 1YN9A 4GS0A 4QAHA 4H34A 1AAXA 2VEVA 5KA1A 1T48A 1OEMX 5EHRA 4JMJA 5K22A 1XXVA 2QCTA 3F99A 2QEPA 1P15A 3MOZA 2F6YA 1PA9A 4J51A 1GFYA 1OESA 1YPTA 3SR9A 4WU2A 3F81A 2CJZA 2GJTA 1YZ4A 2HCMA 4I8NA 3OMHA 1NL9A 4WTYA 3QCJA 4PYHA 2NV5A 3AWEA 4BPCA 4NYHA 3CM3A 3ZM3A 3N0AA 1PXHA 1YTSA 1Q6NA 1C83A 2I6OA 3QCLA 2C46A 5BZZA 3RZ2A 2SHPA 2QCJA 2H04A 3QCFA 3QCDA 3O3LA 2P6XA 5AWXA 3QCGA 5KA2A 3O4TA 3MOWA 2I6IA 1C86A 5BX1A 5K24A 3S4OA 2FJNA 5K9WA 4YAAA 2AHSA 2GWOA 2BGEA 1KAKA 2CMCA 1T49A 2J16A 2QDPA 4GE6A 2CNIA 1LYVA 1G1FA 1RXDA 2CNGA 4IKCA 2H03A 5K9VA 3QCIA 2HXPA 2PBNA 4D3QA 2CM7A 1T4JA 3S3FA 2OUDA 1Q6PA 3ZMQA 2A3KA 3A5JA 4JBCA 3D42A 1X24A 3BLUA 2FH7A 1G4WR 3QCKA 3MMJA 1OHEA 1XBOA 4RH9A 2R0BA 3S3EA 4RI4A 1L8GA 4S0GA 5KABA 2DXPA 2A8BA 1YTNA 2BIJA 3LJ8A 4Z6BA 2I4EA 3F41A 2I6MA 5MMZB 5BUGA 4KYQA 2NT2A 3GXGA 5KA7A 4AZ1A 2I3UA 2QDCA 4TVVA 3O4UA 5KAAA 4QAPA 2QBQA 3GXHA 2I4HA 3F9BA 5KACA 1I9TA 4JNBA 2CMAA 4GFUA 1ZZWA 4GWFA 5M43A 3QCEA 3A5KA 5KA0A 4D3RA 2VEWA 3V0IA 2I4GA 5IBSA 2HNQA 4HJPA 1G7FA 1ONYA 2VEUA 3D1OA 1G1HA 1ZCKA 3V0DA 2HB1A 3CWEA 2HVLA 1C84A 2OOQA 3I80A 1G1GA 2F6WA 4DGXA 4RH5A 4R0SA 3D44A 3S4EA 4PVGA 3ZM0A 3S3KA 5K23A 2CNHA 1OEOX 3EB1A 3RGOA 2BZLA 1M3GA 2B07A 3ZV2A 1PH0A 4GRYA 2QDMA 4RHGA 2VEXA 2F70A 3I7ZA 1OEUA 1I57A 1BZCA 2B49A 1Q6JA 4OHDA 1C88A 3QCHA 1NWEA 4JMKA 3QKPA 1R6HA 4RDDA 2H02A 1V3AA 1G7GA 2CMBA 2E0TA 4OHHA 2GP0A 3ZM2A 1C87A 1XM2A 4QBEA 2OC3A 1FPZA 2WGPA 1QZ0A 4WU3A 3OLRA 4RI5A 1RPMA 2H4VA 2G6ZA 2P4DA 1YFOA 1YGRA 2G59A 1OEVA 3O4SA 3O5XA 1BZJA 1PA1A 2HC2A 2B4OA 5K25A 2H4KA 2QBRA 3D1HA 1EENA 5LXQB 2I3RA 1L8KA 1XRIA 3ZMPA 4NWFA 2M3VA 1ECVA 1U26A 5J8RA 3ZM1A 1A5YA 1PTUA 3U96A 2CM3A 2RF6A 3D9CA 2I6PA 3V0JA 2JJDA 5HDEA 3EAXA 4R0TA 3BM8A 1NWLA 2F6ZA 2F46A 4OHLA 1PTYA 2B4PA 3QCMA 4GE5A 3V0HA 3D1QA 1NNYA 3QCBA 5KA9A 1ZCLA 3BLTA 2QBPA 2Q47A 2HY3A 2ZMMA 2CFVA 3S3HA 1XXPA 2AZRA 3V0GA 2BGDA 3AWGA 2J16B 1BZHA 2MBCA 3NMEA 3V0EA 2F6FA 3QKQA 4KYRA 4MBBA 2IMGA 4ZI4A 2Q05A 1C85A 1YWFA 3AWFA 2J17A 2B3OA 1Q1MA 2ZN7A 3I36A 5KA8A 2I6JA 4YR8B 4ZN5A 1OHCA 4QUMA 2BV5A 3QCNA 5BZXA 3RO1A 2OZ5A 4NNDA 3BRHA 1ONZA 4D3PA 2F6VA 2YDUA 3EMUA 4OHIA 2HNPA 1OHDA 4KI9A 4OHEA 4WOHA 4QUNA 2CNFA 2F6TA 2CNEA 1J4XA 1G4US 1U24A 1U25A 2ESBA 1NZ7A 1LARA 3SMEA 2B4SA 2NZ6A 1MKPA 4NX8A 4RKKA 5KADA 1JF7A 1GWZA 5I6VA 1Q6MA 2VEYA 1JLNA 3RGQA 5KA3A 2FJMA 2B4UA 2NTAA 1YTWA 1SUGA 3EZZA 5IBMA 1WRMA 2I75A 1YGUA 1WCHA 2PA5A 4H1OA 5KA4A 1VHRA 1D5RA 3PS5A 2HC1A 5GTJA 2NT7A 4GE2A 3M4UA 1FPRA 2QBSA 1I9SA 4ZRTA 4HRFA 4HJQA 3H2XA 2I1YA 4QBWA 3F9AA 4BJOA 4DGPA 4Y2EA 2Y2FA 1EEOA 1NO6A 2NLKA 4GRZA 2I5XA 2I42A 3B7OA 4B04A 1PTTA 4ERCA 1PTVA
chains in the Genus database with same CATH superfamily
4NWGA 1E8CA 2AM2A 2PSZA 4GFVA 3V0FA 2Y1OA 5EHPA 2F71A 2UAGA 2JFGA 2H4GA 3EU0A 2GCAA 3QCCA 4R30A 1LQFA 2CM2A 2PQ5A 1Q6TA 1PYNA 2PI7A 1Q6SA 2CM8A 1WAXA 1KAVA 2C7SA 1ZC0A 2Y96A 1OETA 1FQ1A 4Y14A 2PT0A 1GQYA 1QXKA 4ICZA 1YN9A 4GS0A 4QAHA 4H34A 1AAXA 2VEVA 5KA1A 1T48A 1OEMX 5EHRA 4JMJA 5K22A 1XXVA 2QCTA 3F99A 2QEPA 4CVKA 1P15A 3MOZA 2F6YA 1PA9A 4J51A 1GFYA 1OESA 1YPTA 3SR9A 4WU2A 3F81A 2CJZA 2GJTA 1YZ4A 2HCMA 4I8NA 3OMHA 1NL9A 4WTYA 3QCJA 4PYHA 2NV5A 1P3DA 3AWEA 4BPCA 4NYHA 3CM3A 3ZM3A 3N0AA 1PXHA 4C13A 1YTSA 1W7KA 1Q6NA 2GC5A 1C83A 2I6OA 1E0DA 3QCLA 2C46A 5BZZA 3RZ2A 2SHPA 2QCJA 2H04A 2X5OA 3QCFA 3O3LA 3QCDA 2P6XA 5AWXA 3QCGA 5KA2A 3O4TA 3MOWA 2I6IA 3QCZA 1C86A 5BX1A 5K24A 2Y68A 3S4OA 2FJNA 5K9WA 4YAAA 3UAGA 2AHSA 2Y67A 2GWOA 2BGEA 1KAKA 2CMCA 1T49A 2J16A 3ZL8A 2QDPA 4GE6A 2CNIA 1LYVA 1G1FA 1RXDA 2CNGA 4IKCA 2H03A 5K9VA 2JFFA 3QCIA 2HXPA 2PBNA 4D3QA 2CM7A 1T4JA 3S3FA 5A5FA 2OUDA 1Q6PA 3ZMQA 1P31A 2A3KA 4C12A 3A5JA 4JBCA 3D42A 1X24A 2AM1A 3BLUA 2FH7A 1G4WR 3QCKA 3MMJA 1OHEA 1XBOA 4RH9A 2R0BA 3S3EA 4RI4A 1L8GA 4S0GA 5KABA 1EEHA 2DXPA 2A8BA 1YTNA 2BIJA 3LJ8A 4Z6BA 2I4EA 3F41A 2I6MA 5MMZB 5BUGA 4KYQA 2NT2A 3MVNA 3GXGA 1UAGA 5KA7A 4AZ1A 2I3UA 2QDCA 4TVVA 3O4UA 5KAAA 4QAPA 2QBQA 3GXHA 2I4HA 3F9BA 4BUBA 1I9TA 5KACA 4JNBA 3ZM6A 2CMAA 4GFUA 1ZZWA 4GWFA 5M43A 3QCEA 3A5KA 5KA0A 4D3RA 2VEWA 3V0IA 2I4GA 5IBSA 2HNQA 4HJPA 1G7FA 1ONYA 2VEUA 3D1OA 1G1HA 1ZCKA 3V0DA 1GQQA 2HB1A 3CWEA 2HVLA 1C84A 2OOQA 3I80A 1G1GA 2F6WA 4DGXA 4RH5A 2UUPA 4R0SA 3D44A 2GCBA 4PVGA 3S4EA 3ZM0A 3S3KA 5K23A 1JBVA 2CNHA 1OEOX 3EB1A 3RGOA 2BZLA 1M3GA 2B07A 3ZV2A 1PH0A 4GRYA 2VTDA 2QDMA 2Y66A 4RHGA 2VEXA 2F70A 3I7ZA 1OEUA 2GC6A 1I57A 1BZCA 2B49A 1Q6JA 3PYZA 4BUCA 4OHDA 1C88A 3QCHA 1NWEA 4JMKA 3QKPA 1R6HA 4RDDA 2H02A 1V3AA 1G7GA 2CMBA 2E0TA 4OHHA 2GP0A 3ZM2A 1C87A 1XM2A 4ZIYA 4QBEA 2OC3A 1FPZA 2WGPA 1QZ0A 4WU3A 3OLRA 4RI5A 3HN7A 1RPMA 2H4VA 2G6ZA 2P4DA 1YFOA 1YGRA 2G59A 1OEVA 3O4SA 3O5XA 1BZJA 1PA1A 2HC2A 2B4OA 5K25A 2H4KA 2QBRA 3D1HA 4QDIA 1EENA 5LXQB 2I3RA 1L8KA 1XRIA 3ZMPA 4NWFA 2M3VA 4HV4A 1ECVA 1U26A 5J8RA 3ZM1A 1A5YA 1PTUA 5A5EA 3U96A 2CM3A 2RF6A 3D9CA 2I6PA 3ZM5A 1GG4A 3V0JA 2JJDA 5HDEA 3EAXA 4R0TA 3BM8A 1NWLA 2F6ZA 2F46A 4OHLA 1PTYA 2B4PA 3QCMA 4GE5A 3V0HA 3D1QA 1NNYA 3QCBA 5KA9A 2VOSA 1ZCLA 3BLTA 2QBPA 2Q47A 2HY3A 3LK7A 4CVLA 2ZMMA 2CFVA 3S3HA 1XXPA 2AZRA 3V0GA 2BGDA 3AWGA 2J16B 1BZHA 2MBCA 4QF5A 3NMEA 3V0EA 2UUOA 2WTZA 2F6FA 3QKQA 4KYRA 4CVMA 4MBBA 2IMGA 4ZI4A 2Q05A 1C85A 1YWFA 3AWFA 2J17A 2B3OA 1Q1MA 2ZN7A 2XJAA 3I36A 5KA8A 2I6JA 4YR8B 4ZN5A 1OHCA 4QUMA 2BV5A 3QCNA 5BZXA 3RO1A 2OZ5A 4NNDA 3BRHA 1ONZA 4D3PA 2F6VA 2YDUA 3EMUA 2WJPA 4OHIA 2HNPA 1OHDA 4KI9A 4OHEA 4WOHA 4QUNA 3NRSA 2CNFA 2F6TA 2CNEA 1J4XA 1G4US 1U24A 1U25A 2ESBA 2XPCA 1NZ7A 1LARA 3SMEA 2B4SA 2NZ6A 1MKPA 4NX8A 4RKKA 5KADA 1JF7A 1GWZA 5I6VA 1Q6MA 2VEYA 2VTEA 1JLNA 3RGQA 5KA3A 2FJMA 2B4UA 2NTAA 1YTWA 1SUGA 3EZZA 5IBMA 2JFHA 3N2AA 1WRMA 2I75A 4UAGA 1YGUA 1WCHA 2PA5A 2F00A 4H1OA 5KA4A 1VHRA 1W78A 1J6UA 1D5RA 3PS5A 2HC1A 5GTJA 2NT7A 4GE2A 3M4UA 1FPRA 2QBSA 1I9SA 4ZRTA 2VORA 4HRFA 4HJQA 3H2XA 2I1YA 4QBWA 3F9AA 4BJOA 4DGPA 4Y2EA 1O5ZA 2Y2FA 1JBWA 1EEOA 1NO6A 2NLKA 4GRZA 2I5XA 2I42A 3B7OA 4B04A 1FGSA 1PTTA 4ERCA 1PTVA
chains in the Genus database with same CATH topology
4NWGA 2PSZA 4GFVA 3V0FA 5EHPA 2F71A 2H4GA 3EU0A 3QCCA 4R30A 1LQFA 2CM2A 2PQ5A 1Q6TA 1PYNA 2PI7A 1Q6SA 2CM8A 1WAXA 1KAVA 2C7SA 1ZC0A 2Y96A 1OETA 1FQ1A 4Y14A 2PT0A 1QXKA 4ICZA 1YN9A 4GS0A 4QAHA 4H34A 1AAXA 2VEVA 5KA1A 1T48A 1OEMX 5EHRA 4JMJA 5K22A 1XXVA 2QCTA 3F99A 2QEPA 1P15A 3MOZA 2F6YA 1PA9A 4J51A 1GFYA 1OESA 1YPTA 3SR9A 4WU2A 3F81A 2CJZA 2GJTA 1YZ4A 2HCMA 4I8NA 3OMHA 1NL9A 4WTYA 3QCJA 4PYHA 2NV5A 3AWEA 4BPCA 4NYHA 3CM3A 3ZM3A 3N0AA 1PXHA 1YTSA 1Q6NA 1C83A 2I6OA 3QCLA 2C46A 5BZZA 3RZ2A 2SHPA 2QCJA 2H04A 3QCFA 3QCDA 3O3LA 2P6XA 5AWXA 3QCGA 5KA2A 3O4TA 3MOWA 2I6IA 1C86A 5BX1A 5K24A 3S4OA 2FJNA 5K9WA 4YAAA 2AHSA 2GWOA 2BGEA 1KAKA 2CMCA 1T49A 2J16A 2QDPA 4GE6A 2CNIA 1LYVA 1G1FA 1RXDA 2CNGA 4IKCA 2H03A 5K9VA 3QCIA 2HXPA 2PBNA 4D3QA 2CM7A 1T4JA 3S3FA 2OUDA 1Q6PA 3ZMQA 2A3KA 3A5JA 4JBCA 3D42A 1X24A 3BLUA 2FH7A 1G4WR 3QCKA 3MMJA 1OHEA 1XBOA 4RH9A 2R0BA 3S3EA 4RI4A 1L8GA 4S0GA 5KABA 2DXPA 2A8BA 1YTNA 2BIJA 3LJ8A 4Z6BA 2I4EA 3F41A 2I6MA 5MMZB 5BUGA 4KYQA 2NT2A 3GXGA 5KA7A 4AZ1A 2I3UA 2QDCA 4TVVA 3O4UA 5KAAA 4QAPA 2QBQA 3GXHA 2I4HA 3F9BA 5KACA 1I9TA 4JNBA 2CMAA 4GFUA 1ZZWA 4GWFA 5M43A 3QCEA 3A5KA 5KA0A 4D3RA 2VEWA 3V0IA 2I4GA 5IBSA 2HNQA 4HJPA 1G7FA 1ONYA 2VEUA 3D1OA 1G1HA 1ZCKA 3V0DA 2HB1A 3CWEA 2HVLA 1C84A 2OOQA 3I80A 1G1GA 2F6WA 4DGXA 4RH5A 4R0SA 3D44A 3S4EA 4PVGA 3ZM0A 3S3KA 5K23A 2CNHA 1OEOX 3EB1A 3RGOA 2BZLA 1M3GA 2B07A 3ZV2A 1PH0A 4GRYA 2QDMA 4RHGA 2VEXA 2F70A 3I7ZA 1OEUA 1I57A 1BZCA 2B49A 1Q6JA 4OHDA 1C88A 3QCHA 1NWEA 4JMKA 3QKPA 1R6HA 4RDDA 2H02A 1V3AA 1G7GA 2CMBA 2E0TA 4OHHA 2GP0A 3ZM2A 1C87A 1XM2A 4QBEA 2OC3A 1FPZA 2WGPA 1QZ0A 4WU3A 3OLRA 4RI5A 1RPMA 2H4VA 2G6ZA 2P4DA 1YFOA 1YGRA 2G59A 1OEVA 3O4SA 3O5XA 1BZJA 1PA1A 2HC2A 2B4OA 5K25A 2H4KA 2QBRA 3D1HA 1EENA 5LXQB 2I3RA 1L8KA 1XRIA 3ZMPA 4NWFA 2M3VA 1ECVA 1U26A 5J8RA 3ZM1A 1A5YA 1PTUA 3U96A 2CM3A 2RF6A 3D9CA 2I6PA 3V0JA 2JJDA 5HDEA 3EAXA 4R0TA 3BM8A 1NWLA 2F6ZA 2F46A 4OHLA 1PTYA 2B4PA 3QCMA 4GE5A 3V0HA 3D1QA 1NNYA 3QCBA 5KA9A 1ZCLA 3BLTA 2QBPA 2Q47A 2HY3A 2ZMMA 2CFVA 3S3HA 1XXPA 2AZRA 3V0GA 2BGDA 3AWGA 2J16B 1BZHA 2MBCA 3NMEA 3V0EA 2F6FA 3QKQA 4KYRA 4MBBA 2IMGA 4ZI4A 2Q05A 1C85A 1YWFA 3AWFA 2J17A 2B3OA 1Q1MA 2ZN7A 3I36A 5KA8A 2I6JA 4YR8B 4ZN5A 1OHCA 4QUMA 2BV5A 3QCNA 5BZXA 3RO1A 2OZ5A 4NNDA 3BRHA 1ONZA 4D3PA 2F6VA 2YDUA 3EMUA 4OHIA 2HNPA 1OHDA 4KI9A 4OHEA 4WOHA 4QUNA 2CNFA 2F6TA 2CNEA 1J4XA 1G4US 1U24A 1U25A 2ESBA 1NZ7A 1LARA 3SMEA 2B4SA 2NZ6A 1MKPA 4NX8A 4RKKA 5KADA 1JF7A 1GWZA 5I6VA 1Q6MA 2VEYA 1JLNA 3RGQA 5KA3A 2FJMA 2B4UA 2NTAA 1YTWA 1SUGA 3EZZA 5IBMA 1WRMA 2I75A 1YGUA 1WCHA 2PA5A 4H1OA 5KA4A 1VHRA 1D5RA 3PS5A 2HC1A 5GTJA 2NT7A 4GE2A 3M4UA 1FPRA 2QBSA 1I9SA 4ZRTA 4HRFA 4HJQA 3H2XA 2I1YA 4QBWA 3F9AA 4BJOA 4DGPA 4Y2EA 2Y2FA 1EEOA 1NO6A 2NLKA 4GRZA 2I5XA 2I42A 3B7OA 4B04A 1PTTA 4ERCA 1PTVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NWG A;  2PSZ A;  4GFV A;  3V0F A;  5EHP A;  2F71 A;  2H4G A;  3EU0 A;  3QCC A;  4R30 A;  1LQF A;  2CM2 A;  2PQ5 A;  1Q6T A;  1PYN A;  2PI7 A;  1Q6S A;  2CM8 A;  1WAX A;  1KAV A;  2C7S A;  1ZC0 A;  2Y96 A;  1OET A;  1FQ1 A;  4Y14 A;  2PT0 A;  1QXK A;  4ICZ A;  1YN9 A;  4GS0 A;  4QAH A;  4H34 A;  1AAX A;  2VEV A;  5KA1 A;  1T48 A;  1OEM X;  5EHR A;  4JMJ A;  5K22 A;  1XXV A;  2QCT A;  3F99 A;  2QEP A;  1P15 A;  3MOZ A;  2F6Y A;  1PA9 A;  4J51 A;  1GFY A;  1OES A;  1YPT A;  3SR9 A;  4WU2 A;  3F81 A;  2CJZ A;  2GJT A;  1YZ4 A;  2HCM A;  4I8N A;  3OMH A;  1NL9 A;  4WTY A;  3QCJ A;  4PYH A;  2NV5 A;  3AWE A;  4BPC A;  4NYH A;  3CM3 A;  3ZM3 A;  3N0A A;  1PXH A;  1YTS A;  1Q6N A;  1C83 A;  2I6O A;  3QCL A;  2C46 A;  5BZZ A;  3RZ2 A;  2SHP A;  2QCJ A;  2H04 A;  3QCF A;  3QCD A;  3O3L A;  2P6X A;  5AWX A;  3QCG A;  5KA2 A;  3O4T A;  3MOW A;  2I6I A;  1C86 A;  5BX1 A;  5K24 A;  3S4O A;  2FJN A;  5K9W A;  4YAA A;  2AHS A;  2GWO A;  2BGE A;  1KAK A;  2CMC A;  1T49 A;  2J16 A;  2QDP A;  4GE6 A;  2CNI A;  1LYV A;  1G1F A;  1RXD A;  2CNG A;  4IKC A;  2H03 A;  5K9V A;  3QCI A;  2HXP A;  2PBN A;  4D3Q A;  2CM7 A;  1T4J A;  3S3F A;  2OUD A;  1Q6P A;  3ZMQ A;  2A3K A;  3A5J A;  4JBC A;  3D42 A;  1X24 A;  3BLU A;  2FH7 A;  1G4W R;  3QCK A;  3MMJ A;  1OHE A;  1XBO A;  4RH9 A;  2R0B A;  3S3E A;  4RI4 A;  1L8G A;  4S0G A;  5KAB A;  2DXP A;  2A8B A;  1YTN A;  2BIJ A;  3LJ8 A;  4Z6B A;  2I4E A;  3F41 A;  2I6M A;  5MMZ B;  5BUG A;  4KYQ A;  2NT2 A;  3GXG A;  5KA7 A;  4AZ1 A;  2I3U A;  2QDC A;  4TVV A;  3O4U A;  5KAA A;  4QAP A;  2QBQ A;  3GXH A;  2I4H A;  3F9B A;  5KAC A;  1I9T A;  4JNB A;  2CMA A;  4GFU A;  1ZZW A;  4GWF A;  5M43 A;  3QCE A;  3A5K A;  5KA0 A;  4D3R A;  2VEW A;  3V0I A;  2I4G A;  5IBS A;  2HNQ A;  4HJP A;  1G7F A;  1ONY A;  2VEU A;  3D1O A;  1G1H A;  1ZCK A;  3V0D A;  2HB1 A;  3CWE A;  2HVL A;  1C84 A;  2OOQ A;  3I80 A;  1G1G A;  2F6W A;  4DGX A;  4RH5 A;  4R0S A;  3D44 A;  3S4E A;  4PVG A;  3ZM0 A;  3S3K A;  5K23 A;  2CNH A;  1OEO X;  3EB1 A;  3RGO A;  2BZL A;  1M3G A;  2B07 A;  3ZV2 A;  1PH0 A;  4GRY A;  2QDM A;  4RHG A;  2VEX A;  2F70 A;  3I7Z A;  1OEU A;  1I57 A;  1BZC A;  2B49 A;  1Q6J A;  4OHD A;  1C88 A;  3QCH A;  1NWE A;  4JMK A;  3QKP A;  1R6H A;  4RDD A;  2H02 A;  1V3A A;  1G7G A;  2CMB A;  2E0T A;  4OHH A;  2GP0 A;  3ZM2 A;  1C87 A;  1XM2 A;  4QBE A;  2OC3 A;  1FPZ A;  2WGP A;  1QZ0 A;  4WU3 A;  3OLR A;  4RI5 A;  1RPM A;  2H4V A;  2G6Z A;  2P4D A;  1YFO A;  1YGR A;  2G59 A;  1OEV A;  3O4S A;  3O5X A;  1BZJ A;  1PA1 A;  2HC2 A;  2B4O A;  5K25 A;  2H4K A;  2QBR A;  3D1H A;  1EEN A;  5LXQ B;  2I3R A;  1L8K A;  1XRI A;  3ZMP A;  4NWF A;  2M3V A;  1ECV A;  1U26 A;  5J8R A;  3ZM1 A;  1A5Y A;  1PTU A;  3U96 A;  2CM3 A;  2RF6 A;  3D9C A;  2I6P A;  3V0J A;  2JJD A;  5HDE A;  3EAX A;  4R0T A;  3BM8 A;  1NWL A;  2F6Z A;  2F46 A;  4OHL A;  1PTY A;  2B4P A;  3QCM A;  4GE5 A;  3V0H A;  3D1Q A;  1NNY A;  3QCB A;  5KA9 A;  1ZCL A;  3BLT A;  2QBP A;  2Q47 A;  2HY3 A;  2ZMM A;  2CFV A;  3S3H A;  1XXP A;  2AZR A;  3V0G A;  2BGD A;  3AWG A;  2J16 B;  1BZH A;  2MBC A;  3NME A;  3V0E A;  2F6F A;  3QKQ A;  4KYR A;  4MBB A;  2IMG A;  4ZI4 A;  2Q05 A;  1C85 A;  1YWF A;  3AWF A;  2J17 A;  2B3O A;  1Q1M A;  2ZN7 A;  3I36 A;  5KA8 A;  2I6J A;  4YR8 B;  4ZN5 A;  1OHC A;  4QUM A;  2BV5 A;  3QCN A;  5BZX A;  3RO1 A;  2OZ5 A;  4NND A;  3BRH A;  1ONZ A;  4D3P A;  2F6V A;  2YDU A;  3EMU A;  4OHI A;  2HNP A;  1OHD A;  4KI9 A;  4OHE A;  4WOH A;  4QUN A;  2CNF A;  2F6T A;  2CNE A;  1J4X A;  1G4U S;  1U24 A;  1U25 A;  2ESB A;  1NZ7 A;  1LAR A;  3SME A;  2B4S A;  2NZ6 A;  1MKP A;  4NX8 A;  4RKK A;  5KAD A;  1JF7 A;  1GWZ A;  5I6V A;  1Q6M A;  2VEY A;  1JLN A;  3RGQ A;  5KA3 A;  2FJM A;  2B4U A;  2NTA A;  1YTW A;  1SUG A;  3EZZ A;  5IBM A;  1WRM A;  2I75 A;  1YGU A;  1WCH A;  2PA5 A;  4H1O A;  5KA4 A;  1VHR A;  1D5R A;  3PS5 A;  2HC1 A;  5GTJ A;  2NT7 A;  4GE2 A;  3M4U A;  1FPR A;  2QBS A;  1I9S A;  4ZRT A;  4HRF A;  4HJQ A;  3H2X A;  2I1Y A;  4QBW A;  3F9A A;  4BJO A;  4DGP A;  4Y2E A;  2Y2F A;  1EEO A;  1NO6 A;  2NLK A;  4GRZ A;  2I5X A;  2I42 A;  3B7O A;  4B04 A;  1PTT A;  4ERC A;  1PTV A; 
#chains in the Genus database with same CATH topology
 4NWG A;  1E8C A;  2AM2 A;  2PSZ A;  4GFV A;  3V0F A;  2Y1O A;  5EHP A;  2F71 A;  2UAG A;  2JFG A;  2H4G A;  3EU0 A;  2GCA A;  3QCC A;  4R30 A;  1LQF A;  2CM2 A;  2PQ5 A;  1Q6T A;  1PYN A;  2PI7 A;  1Q6S A;  2CM8 A;  1WAX A;  1KAV A;  2C7S A;  1ZC0 A;  2Y96 A;  1OET A;  1FQ1 A;  4Y14 A;  2PT0 A;  1GQY A;  1QXK A;  4ICZ A;  1YN9 A;  4GS0 A;  4QAH A;  4H34 A;  1AAX A;  2VEV A;  5KA1 A;  1T48 A;  1OEM X;  5EHR A;  4JMJ A;  5K22 A;  1XXV A;  2QCT A;  3F99 A;  2QEP A;  4CVK A;  1P15 A;  3MOZ A;  2F6Y A;  1PA9 A;  4J51 A;  1GFY A;  1OES A;  1YPT A;  3SR9 A;  4WU2 A;  3F81 A;  2CJZ A;  2GJT A;  1YZ4 A;  2HCM A;  4I8N A;  3OMH A;  1NL9 A;  4WTY A;  3QCJ A;  4PYH A;  2NV5 A;  1P3D A;  3AWE A;  4BPC A;  4NYH A;  3CM3 A;  3ZM3 A;  3N0A A;  1PXH A;  4C13 A;  1YTS A;  1W7K A;  1Q6N A;  2GC5 A;  1C83 A;  2I6O A;  1E0D A;  3QCL A;  2C46 A;  5BZZ A;  3RZ2 A;  2SHP A;  2QCJ A;  2H04 A;  2X5O A;  3QCF A;  3O3L A;  3QCD A;  2P6X A;  5AWX A;  3QCG A;  5KA2 A;  3O4T A;  3MOW A;  2I6I A;  3QCZ A;  1C86 A;  5BX1 A;  5K24 A;  2Y68 A;  3S4O A;  2FJN A;  5K9W A;  4YAA A;  3UAG A;  2AHS A;  2Y67 A;  2GWO A;  2BGE A;  1KAK A;  2CMC A;  1T49 A;  2J16 A;  3ZL8 A;  2QDP A;  4GE6 A;  2CNI A;  1LYV A;  1G1F A;  1RXD A;  2CNG A;  4IKC A;  2H03 A;  5K9V A;  2JFF A;  3QCI A;  2HXP A;  2PBN A;  4D3Q A;  2CM7 A;  1T4J A;  3S3F A;  5A5F A;  2OUD A;  1Q6P A;  3ZMQ A;  1P31 A;  2A3K A;  4C12 A;  3A5J A;  4JBC A;  3D42 A;  1X24 A;  2AM1 A;  3BLU A;  2FH7 A;  1G4W R;  3QCK A;  3MMJ A;  1OHE A;  1XBO A;  4RH9 A;  2R0B A;  3S3E A;  4RI4 A;  1L8G A;  4S0G A;  5KAB A;  1EEH A;  2DXP A;  2A8B A;  1YTN A;  2BIJ A;  3LJ8 A;  4Z6B A;  2I4E A;  3F41 A;  2I6M A;  5MMZ B;  5BUG A;  4KYQ A;  2NT2 A;  3MVN A;  3GXG A;  1UAG A;  5KA7 A;  4AZ1 A;  2I3U A;  2QDC A;  4TVV A;  3O4U A;  5KAA A;  4QAP A;  2QBQ A;  3GXH A;  2I4H A;  3F9B A;  4BUB A;  1I9T A;  5KAC A;  4JNB A;  3ZM6 A;  2CMA A;  4GFU A;  1ZZW A;  4GWF A;  5M43 A;  3QCE A;  3A5K A;  5KA0 A;  4D3R A;  2VEW A;  3V0I A;  2I4G A;  5IBS A;  2HNQ A;  4HJP A;  1G7F A;  1ONY A;  2VEU A;  3D1O A;  1G1H A;  1ZCK A;  3V0D A;  1GQQ A;  2HB1 A;  3CWE A;  2HVL A;  1C84 A;  2OOQ A;  3I80 A;  1G1G A;  2F6W A;  4DGX A;  4RH5 A;  2UUP A;  4R0S A;  3D44 A;  2GCB A;  4PVG A;  3S4E A;  3ZM0 A;  3S3K A;  5K23 A;  1JBV A;  2CNH A;  1OEO X;  3EB1 A;  3RGO A;  2BZL A;  1M3G A;  2B07 A;  3ZV2 A;  1PH0 A;  4GRY A;  2VTD A;  2QDM A;  2Y66 A;  4RHG A;  2VEX A;  2F70 A;  3I7Z A;  1OEU A;  2GC6 A;  1I57 A;  1BZC A;  2B49 A;  1Q6J A;  3PYZ A;  4BUC A;  4OHD A;  1C88 A;  3QCH A;  1NWE A;  4JMK A;  3QKP A;  1R6H A;  4RDD A;  2H02 A;  1V3A A;  1G7G A;  2CMB A;  2E0T A;  4OHH A;  2GP0 A;  3ZM2 A;  1C87 A;  1XM2 A;  4ZIY A;  4QBE A;  2OC3 A;  1FPZ A;  2WGP A;  1QZ0 A;  4WU3 A;  3OLR A;  4RI5 A;  3HN7 A;  1RPM A;  2H4V A;  2G6Z A;  2P4D A;  1YFO A;  1YGR A;  2G59 A;  1OEV A;  3O4S A;  3O5X A;  1BZJ A;  1PA1 A;  2HC2 A;  2B4O A;  5K25 A;  2H4K A;  2QBR A;  3D1H A;  4QDI A;  1EEN A;  5LXQ B;  2I3R A;  1L8K A;  1XRI A;  3ZMP A;  4NWF A;  2M3V A;  4HV4 A;  1ECV A;  1U26 A;  5J8R A;  3ZM1 A;  1A5Y A;  1PTU A;  5A5E A;  3U96 A;  2CM3 A;  2RF6 A;  3D9C A;  2I6P A;  3ZM5 A;  1GG4 A;  3V0J A;  2JJD A;  5HDE A;  3EAX A;  4R0T A;  3BM8 A;  1NWL A;  2F6Z A;  2F46 A;  4OHL A;  1PTY A;  2B4P A;  3QCM A;  4GE5 A;  3V0H A;  3D1Q A;  1NNY A;  3QCB A;  5KA9 A;  2VOS A;  1ZCL A;  3BLT A;  2QBP A;  2Q47 A;  2HY3 A;  3LK7 A;  4CVL A;  2ZMM A;  2CFV A;  3S3H A;  1XXP A;  2AZR A;  3V0G A;  2BGD A;  3AWG A;  2J16 B;  1BZH A;  2MBC A;  4QF5 A;  3NME A;  3V0E A;  2UUO A;  2WTZ A;  2F6F A;  3QKQ A;  4KYR A;  4CVM A;  4MBB A;  2IMG A;  4ZI4 A;  2Q05 A;  1C85 A;  1YWF A;  3AWF A;  2J17 A;  2B3O A;  1Q1M A;  2ZN7 A;  2XJA A;  3I36 A;  5KA8 A;  2I6J A;  4YR8 B;  4ZN5 A;  1OHC A;  4QUM A;  2BV5 A;  3QCN A;  5BZX A;  3RO1 A;  2OZ5 A;  4NND A;  3BRH A;  1ONZ A;  4D3P A;  2F6V A;  2YDU A;  3EMU A;  2WJP A;  4OHI A;  2HNP A;  1OHD A;  4KI9 A;  4OHE A;  4WOH A;  4QUN A;  3NRS A;  2CNF A;  2F6T A;  2CNE A;  1J4X A;  1G4U S;  1U24 A;  1U25 A;  2ESB A;  2XPC A;  1NZ7 A;  1LAR A;  3SME A;  2B4S A;  2NZ6 A;  1MKP A;  4NX8 A;  4RKK A;  5KAD A;  1JF7 A;  1GWZ A;  5I6V A;  1Q6M A;  2VEY A;  2VTE A;  1JLN A;  3RGQ A;  5KA3 A;  2FJM A;  2B4U A;  2NTA A;  1YTW A;  1SUG A;  3EZZ A;  5IBM A;  2JFH A;  3N2A A;  1WRM A;  2I75 A;  4UAG A;  1YGU A;  1WCH A;  2PA5 A;  2F00 A;  4H1O A;  5KA4 A;  1VHR A;  1W78 A;  1J6U A;  1D5R A;  3PS5 A;  2HC1 A;  5GTJ A;  2NT7 A;  4GE2 A;  3M4U A;  1FPR A;  2QBS A;  1I9S A;  4ZRT A;  2VOR A;  4HRF A;  4HJQ A;  3H2X A;  2I1Y A;  4QBW A;  3F9A A;  4BJO A;  4DGP A;  4Y2E A;  1O5Z A;  2Y2F A;  1JBW A;  1EEO A;  1NO6 A;  2NLK A;  4GRZ A;  2I5X A;  2I42 A;  3B7O A;  4B04 A;  1FGS A;  1PTT A;  4ERC A;  1PTV A; 
#chains in the Genus database with same CATH homology
 4NWG A;  2PSZ A;  4GFV A;  3V0F A;  5EHP A;  2F71 A;  2H4G A;  3EU0 A;  3QCC A;  4R30 A;  1LQF A;  2CM2 A;  2PQ5 A;  1Q6T A;  1PYN A;  2PI7 A;  1Q6S A;  2CM8 A;  1WAX A;  1KAV A;  2C7S A;  1ZC0 A;  2Y96 A;  1OET A;  1FQ1 A;  4Y14 A;  2PT0 A;  1QXK A;  4ICZ A;  1YN9 A;  4GS0 A;  4QAH A;  4H34 A;  1AAX A;  2VEV A;  5KA1 A;  1T48 A;  1OEM X;  5EHR A;  4JMJ A;  5K22 A;  1XXV A;  2QCT A;  3F99 A;  2QEP A;  1P15 A;  3MOZ A;  2F6Y A;  1PA9 A;  4J51 A;  1GFY A;  1OES A;  1YPT A;  3SR9 A;  4WU2 A;  3F81 A;  2CJZ A;  2GJT A;  1YZ4 A;  2HCM A;  4I8N A;  3OMH A;  1NL9 A;  4WTY A;  3QCJ A;  4PYH A;  2NV5 A;  3AWE A;  4BPC A;  4NYH A;  3CM3 A;  3ZM3 A;  3N0A A;  1PXH A;  1YTS A;  1Q6N A;  1C83 A;  2I6O A;  3QCL A;  2C46 A;  5BZZ A;  3RZ2 A;  2SHP A;  2QCJ A;  2H04 A;  3QCF A;  3QCD A;  3O3L A;  2P6X A;  5AWX A;  3QCG A;  5KA2 A;  3O4T A;  3MOW A;  2I6I A;  1C86 A;  5BX1 A;  5K24 A;  3S4O A;  2FJN A;  5K9W A;  4YAA A;  2AHS A;  2GWO A;  2BGE A;  1KAK A;  2CMC A;  1T49 A;  2J16 A;  2QDP A;  4GE6 A;  2CNI A;  1LYV A;  1G1F A;  1RXD A;  2CNG A;  4IKC A;  2H03 A;  5K9V A;  3QCI A;  2HXP A;  2PBN A;  4D3Q A;  2CM7 A;  1T4J A;  3S3F A;  2OUD A;  1Q6P A;  3ZMQ A;  2A3K A;  3A5J A;  4JBC A;  3D42 A;  1X24 A;  3BLU A;  2FH7 A;  1G4W R;  3QCK A;  3MMJ A;  1OHE A;  1XBO A;  4RH9 A;  2R0B A;  3S3E A;  4RI4 A;  1L8G A;  4S0G A;  5KAB A;  2DXP A;  2A8B A;  1YTN A;  2BIJ A;  3LJ8 A;  4Z6B A;  2I4E A;  3F41 A;  2I6M A;  5MMZ B;  5BUG A;  4KYQ A;  2NT2 A;  3GXG A;  5KA7 A;  4AZ1 A;  2I3U A;  2QDC A;  4TVV A;  3O4U A;  5KAA A;  4QAP A;  2QBQ A;  3GXH A;  2I4H A;  3F9B A;  5KAC A;  1I9T A;  4JNB A;  2CMA A;  4GFU A;  1ZZW A;  4GWF A;  5M43 A;  3QCE A;  3A5K A;  5KA0 A;  4D3R A;  2VEW A;  3V0I A;  2I4G A;  5IBS A;  2HNQ A;  4HJP A;  1G7F A;  1ONY A;  2VEU A;  3D1O A;  1G1H A;  1ZCK A;  3V0D A;  2HB1 A;  3CWE A;  2HVL A;  1C84 A;  2OOQ A;  3I80 A;  1G1G A;  2F6W A;  4DGX A;  4RH5 A;  4R0S A;  3D44 A;  3S4E A;  4PVG A;  3ZM0 A;  3S3K A;  5K23 A;  2CNH A;  1OEO X;  3EB1 A;  3RGO A;  2BZL A;  1M3G A;  2B07 A;  3ZV2 A;  1PH0 A;  4GRY A;  2QDM A;  4RHG A;  2VEX A;  2F70 A;  3I7Z A;  1OEU A;  1I57 A;  1BZC A;  2B49 A;  1Q6J A;  4OHD A;  1C88 A;  3QCH A;  1NWE A;  4JMK A;  3QKP A;  1R6H A;  4RDD A;  2H02 A;  1V3A A;  1G7G A;  2CMB A;  2E0T A;  4OHH A;  2GP0 A;  3ZM2 A;  1C87 A;  1XM2 A;  4QBE A;  2OC3 A;  1FPZ A;  2WGP A;  1QZ0 A;  4WU3 A;  3OLR A;  4RI5 A;  1RPM A;  2H4V A;  2G6Z A;  2P4D A;  1YFO A;  1YGR A;  2G59 A;  1OEV A;  3O4S A;  3O5X A;  1BZJ A;  1PA1 A;  2HC2 A;  2B4O A;  5K25 A;  2H4K A;  2QBR A;  3D1H A;  1EEN A;  5LXQ B;  2I3R A;  1L8K A;  1XRI A;  3ZMP A;  4NWF A;  2M3V A;  1ECV A;  1U26 A;  5J8R A;  3ZM1 A;  1A5Y A;  1PTU A;  3U96 A;  2CM3 A;  2RF6 A;  3D9C A;  2I6P A;  3V0J A;  2JJD A;  5HDE A;  3EAX A;  4R0T A;  3BM8 A;  1NWL A;  2F6Z A;  2F46 A;  4OHL A;  1PTY A;  2B4P A;  3QCM A;  4GE5 A;  3V0H A;  3D1Q A;  1NNY A;  3QCB A;  5KA9 A;  1ZCL A;  3BLT A;  2QBP A;  2Q47 A;  2HY3 A;  2ZMM A;  2CFV A;  3S3H A;  1XXP A;  2AZR A;  3V0G A;  2BGD A;  3AWG A;  2J16 B;  1BZH A;  2MBC A;  3NME A;  3V0E A;  2F6F A;  3QKQ A;  4KYR A;  4MBB A;  2IMG A;  4ZI4 A;  2Q05 A;  1C85 A;  1YWF A;  3AWF A;  2J17 A;  2B3O A;  1Q1M A;  2ZN7 A;  3I36 A;  5KA8 A;  2I6J A;  4YR8 B;  4ZN5 A;  1OHC A;  4QUM A;  2BV5 A;  3QCN A;  5BZX A;  3RO1 A;  2OZ5 A;  4NND A;  3BRH A;  1ONZ A;  4D3P A;  2F6V A;  2YDU A;  3EMU A;  4OHI A;  2HNP A;  1OHD A;  4KI9 A;  4OHE A;  4WOH A;  4QUN A;  2CNF A;  2F6T A;  2CNE A;  1J4X A;  1G4U S;  1U24 A;  1U25 A;  2ESB A;  1NZ7 A;  1LAR A;  3SME A;  2B4S A;  2NZ6 A;  1MKP A;  4NX8 A;  4RKK A;  5KAD A;  1JF7 A;  1GWZ A;  5I6V A;  1Q6M A;  2VEY A;  1JLN A;  3RGQ A;  5KA3 A;  2FJM A;  2B4U A;  2NTA A;  1YTW A;  1SUG A;  3EZZ A;  5IBM A;  1WRM A;  2I75 A;  1YGU A;  1WCH A;  2PA5 A;  4H1O A;  5KA4 A;  1VHR A;  1D5R A;  3PS5 A;  2HC1 A;  5GTJ A;  2NT7 A;  4GE2 A;  3M4U A;  1FPR A;  2QBS A;  1I9S A;  4ZRT A;  4HRF A;  4HJQ A;  3H2X A;  2I1Y A;  4QBW A;  3F9A A;  4BJO A;  4DGP A;  4Y2E A;  2Y2F A;  1EEO A;  1NO6 A;  2NLK A;  4GRZ A;  2I5X A;  2I42 A;  3B7O A;  4B04 A;  1PTT A;  4ERC A;  1PTV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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