4F6HA

Mutagenesis of zinc ligand residue cys221 reveals plasticity in the imp-1 metallo-b-lactamase active site
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
233
structure length
223
Chain Sequence
LPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNAEAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELTNELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGGFIKPYGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESHPQFEK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutagenesis of zinc ligand residue Cys221 reveals plasticity in the IMP-1 metallo-beta-lactamase active site
pubmed doi rcsb
molecule tags Hydrolase
source organism Pseudomonas aeruginosa
molecule keywords Beta-lactamase
total genus 57
structure length 223
sequence length 233
ec nomenclature
pdb deposition date 2012-05-14
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 4f6hA00
4C1EA 2NZFA 2BG8A 1X8HA 1VGNA 4HKYA 2Q9UA 3ZNBA 3ADRA 3BK2A 5B3RA 4GYQA 3SPUA 5A5ZA 4EYLA 2HB9A 3LVZA 4NQ2A 2BFLA 3JXPA 4TZFA 1KO2A 5HIPA 1Y44A 4NQ6A 3DHBA 4D1WA 4DIKA 2GFKA 3VQZA 3ZWFA 4TYTA 2FM6A 5B1UA 4HL2A 5EVDA 2BTNA 2FU7A 5LCHA 4O98A 2CBNA 3AJ3A 4BZ3A 2GFJA 4EFZA 1ZTCA 2WHGA 4DILA 4D1UA 3X30A 4NQ5A 3T3OA 5AHRA 3MD7A 3DH8A 2GKLA 2WRSA 5LE1A 3I15A 3PY5A 5HH6A 3G1PA 3SRXA 5IQKA 2Q0JA 4P62A 4C1FA 4YSBA 2YZ3A 2ZZIA 4C1GA 1XM8A 2DOOA 5DPXA 4ZO3A 3IE0A 4GCWA 5FQBA 2BFZB 2QJSA 5ACXA 4H0DA 4ZEJA 3IDZA 2BIBA 2I7TA 2ZWRA 3F9OA 5HISA 2P4ZA 2WYMC 1KO3A 1DDKA 1JJTA 2A7MA 4F6HA 4RL2A 5K0WA 1A8TA 3A4YA 3IOFA 3ESHA 5AXRA 1BMCA 5LM6A 1WUPA 3IE1A 4Z67A 4PVTA 4UWRB 2XR1A 5EV6A 4EXSA 5KIKA 4D02A 2VW8A 4Z5YA 5LS3A 4C1HA 4TZ9A 1X8IA 3BC2A 2AIOA 3T3NA 1DXKA 4FSBA 4F6ZA 3FAIA 4ZNBA 3AF6A 4CHLA 1P9EA 2I7XA 2BGAA 5ACPA 2YCBA 2M5DA 5AXOA 5LSCA 5EH9A 3X2XA 4RL0A 4J5FA 4Z7RA 3DHCA 3RKKA 4Z5ZA 3S0ZA 3I11A 4C1CA 4HL1A 4TYFA 4EY2A 2I7VA 5LCAA 2QINA 3X2ZA 4V0HA 3IOGA 3RKJA 1HLKA 1BVTA 4RAWA 2BFZA 2FHXA 5FQCA 1YCHA 5EHTA 4RBSA 4UWOB 3BK1A 1JT1A 4B87A 4JO0A 3VPEA 4RAMA 1E5DA 2OHHA 4KEPA 2H6AA 4XWTA 4PVOA 5LLDA 2WYLA 3I13A 1KR3A 5A0VA 2DKFA 2YNUA 2BFKA 4XWWA 5K4MA 2YNVB 2P1EA 3Q6VA 1SMLA 4J5HA 2FHXB 4C1DA 2Y8AA 4YSLA 2Y87A 4ZO2A 3ZR9A 2QDSA 1VJNA 3AF5A 2ZNBA 4Z60A 2E7YA 3DHAA 4KEQA 5LCFA 4UBQA 4AWZA 3R2UA 3SW3A 5EV8A 2BC2A 4Z6XA 3PG4A 5ACRA 4D1VA 3H3EA 2GMNA 1DD6A 5HIQA 1XTOA 3X2YA 4D1TA 2QEDA 5LMCA 2UYXA 5ACQA 3I0VA 1ZNBA 4NQ4A 2NYPA 5AYAA 2YNTA 5A87A 5AHOA 1YCFA 3TP9A 5A0TA 3SFPA 5ACSA 2P18A 4TZEA 5K4KA 2FU6A 2NZEA 5HH4A 3IE2A 3SD9A 5ACWA 3PY6A 3BV6A 4C09A 1BC2A 3KNSA 5ACUA 4LE6A 4UA4A 2R2DA 3IEKA 2XF4A 4U4LA 4TZBA 2YNTB 5K4NA 4EXYA 4YSKA 2BR6A 5AEBA 2BG8B 3P2UA 2YNVA 3L6NA 5B15A 4AX1B 5HIOA 1M2XA 1YCGA 2Q0IA 3FCZA 1WUOA 5KILA 1ZKPA 4RM5A 4AWYB 2M5CA 5EVKA 3IEMA 1JJEA 2AZ4A 2BG7A 5FQAA 4UWSB 2BG2A 4BP0A 3KL7A 1QH5A 1MQOA 4AD9A 4XUKA 4FEKA 2GCUA 3I14A 2Q42A 1X8GA 5EVBA 3WXCA 2NXAA 4EYBA 1K07A 2P97A 4UWPB 2BG6A 5ACVA 1WRAA 2FU9A 1WW1A 3RPCA 3SBLA 4EYFA 2ZO4A 3T9MA 2Y8BA 3KNRA 1L9YA 4FR7A 4WD6A 5ACTA 3IELA 4GYUA 1A7TA 2OHJA 2FK6A 5EWAA 2YNWA 5HH5A 4UAMA 2QDTA 2OHIA 2WYMA 1QH3A 1VMEA 3QH8A 3ZQ4A 5EW0A 4AX0B 2BMIA 2FU8A
chains in the Genus database with same CATH superfamily
4C1EA 2YHEA 2NZFA 2BG8A 1X8HA 1VGNA 4HKYA 2Q9UA 3ZNBA 3ADRA 3BK2A 5B3RA 4GYQA 3SPUA 5A5ZA 4EYLA 2HB9A 3LVZA 4NQ2A 2BFLA 3JXPA 4TZFA 1KO2A 5HIPA 1Y44A 4NQ6A 3DHBA 4D1WA 4DIKA 2GFKA 3VQZA 3ZWFA 4TYTA 2FM6A 5B1UA 4HL2A 5EVDA 2BTNA 2FU7A 5LCHA 4O98A 2CBNA 3AJ3A 4BZ3A 2GFJA 4EFZA 1ZTCA 2CG3A 2WHGA 4DILA 4D1UA 3X30A 4NQ5A 3T3OA 5AHRA 3MD7A 3DH8A 2GKLA 2WRSA 5LE1A 3I15A 3PY5A 5HH6A 3G1PA 3SRXA 5IQKA 2Q0JA 4P62A 4C1FA 4YSBA 2YZ3A 2ZZIA 4C1GA 1XM8A 2DOOA 5DPXA 4ZO3A 3IE0A 4GCWA 5FQBA 2BFZB 2QJSA 5ACXA 4AXHA 4H0DA 4ZEJA 3IDZA 2BIBA 2I7TA 2ZWRA 3F9OA 5HISA 2P4ZA 4AV7A 2WYMC 1KO3A 1DDKA 1JJTA 2A7MA 4F6HA 4RL2A 5K0WA 1A8TA 3A4YA 3IOFA 3ESHA 5AXRA 1BMCA 5LM6A 1WUPA 3IE1A 4Z67A 4PVTA 4UWRB 2XR1A 5EV6A 4EXSA 5KIKA 4D02A 2VW8A 4Z5YA 5LS3A 4C1HA 4TZ9A 1X8IA 3BC2A 5AIJA 2AIOA 3T3NA 1DXKA 4FSBA 4F6ZA 3FAIA 4ZNBA 3AF6A 4CHLA 4NURA 1P9EA 2I7XA 2BGAA 5ACPA 2YCBA 2M5DA 5AXOA 5LSCA 5EH9A 3X2XA 4RL0A 4J5FA 4Z7RA 3DHCA 3RKKA 4Z5ZA 3S0ZA 3I11A 4C1CA 4HL1A 4TYFA 4EY2A 2I7VA 5LCAA 2QINA 3X2ZA 4V0HA 3IOGA 3RKJA 1HLKA 1BVTA 4RAWA 2BFZA 2FHXA 5FQCA 1YCHA 5EHTA 4RBSA 4UWOB 3BK1A 1JT1A 4B87A 4JO0A 3VPEA 4RAMA 1E5DA 2OHHA 4KEPA 2H6AA 4XWTA 4PVOA 5LLDA 2WYLA 3I13A 1KR3A 5A0VA 2DKFA 2YNUA 2BFKA 4XWWA 5K4MA 2YNVB 2P1EA 3Q6VA 1SMLA 4J5HA 2FHXB 4C1DA 2Y8AA 4YSLA 2Y87A 4ZO2A 3ZR9A 2QDSA 1VJNA 3AF5A 2ZNBA 4Z60A 2E7YA 3DHAA 4KEQA 5LCFA 4UBQA 4AWZA 3R2UA 3SW3A 5EV8A 2BC2A 4Z6XA 3PG4A 5ACRA 4D1VA 3H3EA 2GMNA 1DD6A 5HIQA 1XTOA 3X2YA 4D1TA 2QEDA 5LMCA 2UYXA 5ACQA 5AJLA 3I0VA 1ZNBA 4NQ4A 2NYPA 5AYAA 2YNTA 5A87A 5AHOA 1YCFA 3TP9A 5A0TA 3SFPA 5ACSA 2P18A 4PDXA 4TZEA 5K4KA 2FU6A 2NZEA 5HH4A 3IE2A 3SD9A 5ACWA 3PY6A 3BV6A 4C09A 1BC2A 3KNSA 5ACUA 4LE6A 4UA4A 2R2DA 3IEKA 2XF4A 2CG2A 5A23A 4U4LA 2CFZA 4TZBA 2YNTB 5K4NA 4EXYA 4YSKA 2BR6A 5AEBA 2BG8B 3P2UA 2YNVA 3L6NA 5B15A 4AX1B 5HIOA 1M2XA 1YCGA 2Q0IA 3FCZA 1WUOA 5KILA 1ZKPA 4RM5A 4AWYB 2M5CA 5EVKA 3IEMA 1JJEA 2AZ4A 2BG7A 5FQAA 4UWSB 2BG2A 4BP0A 3KL7A 1QH5A 1MQOA 4AD9A 4XUKA 4FEKA 2GCUA 3I14A 2Q42A 1X8GA 5EVBA 3WXCA 2NXAA 4EYBA 1K07A 2P97A 4UWPB 2BG6A 5ACVA 1WRAA 2FU9A 1WW1A 3RPCA 3SBLA 4EYFA 2ZO4A 3T9MA 2Y8BA 3KNRA 1L9YA 4FR7A 4WD6A 5ACTA 3IELA 4GYUA 2CFUA 1A7TA 2OHJA 2FK6A 5EWAA 2YNWA 5HH5A 4UAMA 2QDTA 2OHIA 2WYMA 1QH3A 1VMEA 3QH8A 3ZQ4A 5EW0A 4AX0B 2BMIA 2FU8A
chains in the Genus database with same CATH topology
4C1EA 2NZFA 2BG8A 1X8HA 1VGNA 4HKYA 2Q9UA 3ZNBA 3ADRA 3BK2A 5B3RA 4GYQA 3SPUA 5A5ZA 4EYLA 2HB9A 3LVZA 4NQ2A 2BFLA 3JXPA 4TZFA 1KO2A 5HIPA 1Y44A 4NQ6A 3DHBA 4D1WA 4DIKA 2GFKA 3VQZA 3ZWFA 4TYTA 2FM6A 5B1UA 4HL2A 5EVDA 2BTNA 2FU7A 5LCHA 4O98A 2CBNA 3AJ3A 4BZ3A 2GFJA 4EFZA 1ZTCA 2WHGA 4DILA 4D1UA 3X30A 4NQ5A 3T3OA 5AHRA 3MD7A 3DH8A 2GKLA 2WRSA 5LE1A 3I15A 3PY5A 5HH6A 3G1PA 3SRXA 5IQKA 2Q0JA 4P62A 4C1FA 4YSBA 2YZ3A 2ZZIA 4C1GA 1XM8A 2DOOA 5DPXA 4ZO3A 3IE0A 4GCWA 5FQBA 2BFZB 2QJSA 5ACXA 4H0DA 4ZEJA 3IDZA 2BIBA 2I7TA 2ZWRA 3F9OA 5HISA 2P4ZA 2WYMC 1KO3A 1DDKA 1JJTA 2A7MA 4F6HA 4RL2A 5K0WA 1A8TA 3A4YA 3IOFA 3ESHA 5AXRA 1BMCA 5LM6A 1WUPA 3IE1A 4Z67A 4PVTA 4UWRB 2XR1A 5EV6A 4EXSA 5KIKA 4D02A 2VW8A 4Z5YA 5LS3A 4C1HA 4TZ9A 1X8IA 3BC2A 2AIOA 3T3NA 1DXKA 4FSBA 4F6ZA 3FAIA 4ZNBA 3AF6A 4CHLA 1P9EA 2I7XA 2BGAA 5ACPA 2YCBA 2M5DA 5AXOA 5LSCA 5EH9A 3X2XA 4RL0A 4J5FA 4Z7RA 3DHCA 3RKKA 4Z5ZA 3S0ZA 3I11A 4C1CA 4HL1A 4TYFA 4EY2A 2I7VA 5LCAA 2QINA 3X2ZA 4V0HA 3IOGA 3RKJA 1HLKA 1BVTA 4RAWA 2BFZA 2FHXA 5FQCA 1YCHA 5EHTA 4RBSA 4UWOB 3BK1A 1JT1A 4B87A 4JO0A 3VPEA 4RAMA 1E5DA 2OHHA 4KEPA 2H6AA 4XWTA 4PVOA 5LLDA 2WYLA 3I13A 1KR3A 5A0VA 2DKFA 2YNUA 2BFKA 4XWWA 5K4MA 2YNVB 2P1EA 3Q6VA 1SMLA 4J5HA 2FHXB 4C1DA 2Y8AA 4YSLA 2Y87A 4ZO2A 3ZR9A 2QDSA 1VJNA 3AF5A 2ZNBA 4Z60A 2E7YA 3DHAA 4KEQA 5LCFA 4UBQA 4AWZA 3R2UA 3SW3A 5EV8A 2BC2A 4Z6XA 3PG4A 5ACRA 4D1VA 3H3EA 2GMNA 1DD6A 5HIQA 1XTOA 3X2YA 4D1TA 2QEDA 5LMCA 2UYXA 5ACQA 3I0VA 1ZNBA 4NQ4A 2NYPA 5AYAA 2YNTA 5A87A 5AHOA 1YCFA 3TP9A 5A0TA 3SFPA 5ACSA 2P18A 4TZEA 5K4KA 2FU6A 2NZEA 5HH4A 3IE2A 3SD9A 5ACWA 3PY6A 3BV6A 4C09A 1BC2A 3KNSA 5ACUA 4LE6A 4UA4A 2R2DA 3IEKA 2XF4A 4U4LA 4TZBA 2YNTB 5K4NA 4EXYA 4YSKA 2BR6A 5AEBA 2BG8B 3P2UA 2YNVA 3L6NA 5B15A 4AX1B 5HIOA 1M2XA 1YCGA 2Q0IA 3FCZA 1WUOA 5KILA 1ZKPA 4RM5A 4AWYB 2M5CA 5EVKA 3IEMA 1JJEA 2AZ4A 2BG7A 5FQAA 4UWSB 2BG2A 4BP0A 3KL7A 1QH5A 1MQOA 4AD9A 4XUKA 4FEKA 2GCUA 3I14A 2Q42A 1X8GA 5EVBA 3WXCA 2NXAA 4EYBA 1K07A 2P97A 4UWPB 2BG6A 5ACVA 1WRAA 2FU9A 1WW1A 3RPCA 3SBLA 4EYFA 2ZO4A 3T9MA 2Y8BA 3KNRA 1L9YA 4FR7A 4WD6A 5ACTA 3IELA 4GYUA 1A7TA 2OHJA 2FK6A 5EWAA 2YNWA 5HH5A 4UAMA 2QDTA 2OHIA 2WYMA 1QH3A 1VMEA 3QH8A 3ZQ4A 5EW0A 4AX0B 2BMIA 2FU8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4C1E A;  2NZF A;  2BG8 A;  1X8H A;  1VGN A;  4HKY A;  2Q9U A;  3ZNB A;  3ADR A;  3BK2 A;  5B3R A;  4GYQ A;  3SPU A;  5A5Z A;  4EYL A;  2HB9 A;  3LVZ A;  4NQ2 A;  2BFL A;  3JXP A;  4TZF A;  1KO2 A;  5HIP A;  1Y44 A;  4NQ6 A;  3DHB A;  4D1W A;  4DIK A;  2GFK A;  3VQZ A;  3ZWF A;  4TYT A;  2FM6 A;  5B1U A;  4HL2 A;  5EVD A;  2BTN A;  2FU7 A;  5LCH A;  4O98 A;  2CBN A;  3AJ3 A;  4BZ3 A;  2GFJ A;  4EFZ A;  1ZTC A;  2WHG A;  4DIL A;  4D1U A;  3X30 A;  4NQ5 A;  3T3O A;  5AHR A;  3MD7 A;  3DH8 A;  2GKL A;  2WRS A;  5LE1 A;  3I15 A;  3PY5 A;  5HH6 A;  3G1P A;  3SRX A;  5IQK A;  2Q0J A;  4P62 A;  4C1F A;  4YSB A;  2YZ3 A;  2ZZI A;  4C1G A;  1XM8 A;  2DOO A;  5DPX A;  4ZO3 A;  3IE0 A;  4GCW A;  5FQB A;  2BFZ B;  2QJS A;  5ACX A;  4H0D A;  4ZEJ A;  3IDZ A;  2BIB A;  2I7T A;  2ZWR A;  3F9O A;  5HIS A;  2P4Z A;  2WYM C;  1KO3 A;  1DDK A;  1JJT A;  2A7M A;  4F6H A;  4RL2 A;  5K0W A;  1A8T A;  3A4Y A;  3IOF A;  3ESH A;  5AXR A;  1BMC A;  5LM6 A;  1WUP A;  3IE1 A;  4Z67 A;  4PVT A;  4UWR B;  2XR1 A;  5EV6 A;  4EXS A;  5KIK A;  4D02 A;  2VW8 A;  4Z5Y A;  5LS3 A;  4C1H A;  4TZ9 A;  1X8I A;  3BC2 A;  2AIO A;  3T3N A;  1DXK A;  4FSB A;  4F6Z A;  3FAI A;  4ZNB A;  3AF6 A;  4CHL A;  1P9E A;  2I7X A;  2BGA A;  5ACP A;  2YCB A;  2M5D A;  5AXO A;  5LSC A;  5EH9 A;  3X2X A;  4RL0 A;  4J5F A;  4Z7R A;  3DHC A;  3RKK A;  4Z5Z A;  3S0Z A;  3I11 A;  4C1C A;  4HL1 A;  4TYF A;  4EY2 A;  2I7V A;  5LCA A;  2QIN A;  3X2Z A;  4V0H A;  3IOG A;  3RKJ A;  1HLK A;  1BVT A;  4RAW A;  2BFZ A;  2FHX A;  5FQC A;  1YCH A;  5EHT A;  4RBS A;  4UWO B;  3BK1 A;  1JT1 A;  4B87 A;  4JO0 A;  3VPE A;  4RAM A;  1E5D A;  2OHH A;  4KEP A;  2H6A A;  4XWT A;  4PVO A;  5LLD A;  2WYL A;  3I13 A;  1KR3 A;  5A0V A;  2DKF A;  2YNU A;  2BFK A;  4XWW A;  5K4M A;  2YNV B;  2P1E A;  3Q6V A;  1SML A;  4J5H A;  2FHX B;  4C1D A;  2Y8A A;  4YSL A;  2Y87 A;  4ZO2 A;  3ZR9 A;  2QDS A;  1VJN A;  3AF5 A;  2ZNB A;  4Z60 A;  2E7Y A;  3DHA A;  4KEQ A;  5LCF A;  4UBQ A;  4AWZ A;  3R2U A;  3SW3 A;  5EV8 A;  2BC2 A;  4Z6X A;  3PG4 A;  5ACR A;  4D1V A;  3H3E A;  2GMN A;  1DD6 A;  5HIQ A;  1XTO A;  3X2Y A;  4D1T A;  2QED A;  5LMC A;  2UYX A;  5ACQ A;  3I0V A;  1ZNB A;  4NQ4 A;  2NYP A;  5AYA A;  2YNT A;  5A87 A;  5AHO A;  1YCF A;  3TP9 A;  5A0T A;  3SFP A;  5ACS A;  2P18 A;  4TZE A;  5K4K A;  2FU6 A;  2NZE A;  5HH4 A;  3IE2 A;  3SD9 A;  5ACW A;  3PY6 A;  3BV6 A;  4C09 A;  1BC2 A;  3KNS A;  5ACU A;  4LE6 A;  4UA4 A;  2R2D A;  3IEK A;  2XF4 A;  4U4L A;  4TZB A;  2YNT B;  5K4N A;  4EXY A;  4YSK A;  2BR6 A;  5AEB A;  2BG8 B;  3P2U A;  2YNV A;  3L6N A;  5B15 A;  4AX1 B;  5HIO A;  1M2X A;  1YCG A;  2Q0I A;  3FCZ A;  1WUO A;  5KIL A;  1ZKP A;  4RM5 A;  4AWY B;  2M5C A;  5EVK A;  3IEM A;  1JJE A;  2AZ4 A;  2BG7 A;  5FQA A;  4UWS B;  2BG2 A;  4BP0 A;  3KL7 A;  1QH5 A;  1MQO A;  4AD9 A;  4XUK A;  4FEK A;  2GCU A;  3I14 A;  2Q42 A;  1X8G A;  5EVB A;  3WXC A;  2NXA A;  4EYB A;  1K07 A;  2P97 A;  4UWP B;  2BG6 A;  5ACV A;  1WRA A;  2FU9 A;  1WW1 A;  3RPC A;  3SBL A;  4EYF A;  2ZO4 A;  3T9M A;  2Y8B A;  3KNR A;  1L9Y A;  4FR7 A;  4WD6 A;  5ACT A;  3IEL A;  4GYU A;  1A7T A;  2OHJ A;  2FK6 A;  5EWA A;  2YNW A;  5HH5 A;  4UAM A;  2QDT A;  2OHI A;  2WYM A;  1QH3 A;  1VME A;  3QH8 A;  3ZQ4 A;  5EW0 A;  4AX0 B;  2BMI A;  2FU8 A; 
#chains in the Genus database with same CATH topology
 4C1E A;  2YHE A;  2NZF A;  2BG8 A;  1X8H A;  1VGN A;  4HKY A;  2Q9U A;  3ZNB A;  3ADR A;  3BK2 A;  5B3R A;  4GYQ A;  3SPU A;  5A5Z A;  4EYL A;  2HB9 A;  3LVZ A;  4NQ2 A;  2BFL A;  3JXP A;  4TZF A;  1KO2 A;  5HIP A;  1Y44 A;  4NQ6 A;  3DHB A;  4D1W A;  4DIK A;  2GFK A;  3VQZ A;  3ZWF A;  4TYT A;  2FM6 A;  5B1U A;  4HL2 A;  5EVD A;  2BTN A;  2FU7 A;  5LCH A;  4O98 A;  2CBN A;  3AJ3 A;  4BZ3 A;  2GFJ A;  4EFZ A;  1ZTC A;  2CG3 A;  2WHG A;  4DIL A;  4D1U A;  3X30 A;  4NQ5 A;  3T3O A;  5AHR A;  3MD7 A;  3DH8 A;  2GKL A;  2WRS A;  5LE1 A;  3I15 A;  3PY5 A;  5HH6 A;  3G1P A;  3SRX A;  5IQK A;  2Q0J A;  4P62 A;  4C1F A;  4YSB A;  2YZ3 A;  2ZZI A;  4C1G A;  1XM8 A;  2DOO A;  5DPX A;  4ZO3 A;  3IE0 A;  4GCW A;  5FQB A;  2BFZ B;  2QJS A;  5ACX A;  4AXH A;  4H0D A;  4ZEJ A;  3IDZ A;  2BIB A;  2I7T A;  2ZWR A;  3F9O A;  5HIS A;  2P4Z A;  4AV7 A;  2WYM C;  1KO3 A;  1DDK A;  1JJT A;  2A7M A;  4F6H A;  4RL2 A;  5K0W A;  1A8T A;  3A4Y A;  3IOF A;  3ESH A;  5AXR A;  1BMC A;  5LM6 A;  1WUP A;  3IE1 A;  4Z67 A;  4PVT A;  4UWR B;  2XR1 A;  5EV6 A;  4EXS A;  5KIK A;  4D02 A;  2VW8 A;  4Z5Y A;  5LS3 A;  4C1H A;  4TZ9 A;  1X8I A;  3BC2 A;  5AIJ A;  2AIO A;  3T3N A;  1DXK A;  4FSB A;  4F6Z A;  3FAI A;  4ZNB A;  3AF6 A;  4CHL A;  4NUR A;  1P9E A;  2I7X A;  2BGA A;  5ACP A;  2YCB A;  2M5D A;  5AXO A;  5LSC A;  5EH9 A;  3X2X A;  4RL0 A;  4J5F A;  4Z7R A;  3DHC A;  3RKK A;  4Z5Z A;  3S0Z A;  3I11 A;  4C1C A;  4HL1 A;  4TYF A;  4EY2 A;  2I7V A;  5LCA A;  2QIN A;  3X2Z A;  4V0H A;  3IOG A;  3RKJ A;  1HLK A;  1BVT A;  4RAW A;  2BFZ A;  2FHX A;  5FQC A;  1YCH A;  5EHT A;  4RBS A;  4UWO B;  3BK1 A;  1JT1 A;  4B87 A;  4JO0 A;  3VPE A;  4RAM A;  1E5D A;  2OHH A;  4KEP A;  2H6A A;  4XWT A;  4PVO A;  5LLD A;  2WYL A;  3I13 A;  1KR3 A;  5A0V A;  2DKF A;  2YNU A;  2BFK A;  4XWW A;  5K4M A;  2YNV B;  2P1E A;  3Q6V A;  1SML A;  4J5H A;  2FHX B;  4C1D A;  2Y8A A;  4YSL A;  2Y87 A;  4ZO2 A;  3ZR9 A;  2QDS A;  1VJN A;  3AF5 A;  2ZNB A;  4Z60 A;  2E7Y A;  3DHA A;  4KEQ A;  5LCF A;  4UBQ A;  4AWZ A;  3R2U A;  3SW3 A;  5EV8 A;  2BC2 A;  4Z6X A;  3PG4 A;  5ACR A;  4D1V A;  3H3E A;  2GMN A;  1DD6 A;  5HIQ A;  1XTO A;  3X2Y A;  4D1T A;  2QED A;  5LMC A;  2UYX A;  5ACQ A;  5AJL A;  3I0V A;  1ZNB A;  4NQ4 A;  2NYP A;  5AYA A;  2YNT A;  5A87 A;  5AHO A;  1YCF A;  3TP9 A;  5A0T A;  3SFP A;  5ACS A;  2P18 A;  4PDX A;  4TZE A;  5K4K A;  2FU6 A;  2NZE A;  5HH4 A;  3IE2 A;  3SD9 A;  5ACW A;  3PY6 A;  3BV6 A;  4C09 A;  1BC2 A;  3KNS A;  5ACU A;  4LE6 A;  4UA4 A;  2R2D A;  3IEK A;  2XF4 A;  2CG2 A;  5A23 A;  4U4L A;  2CFZ A;  4TZB A;  2YNT B;  5K4N A;  4EXY A;  4YSK A;  2BR6 A;  5AEB A;  2BG8 B;  3P2U A;  2YNV A;  3L6N A;  5B15 A;  4AX1 B;  5HIO A;  1M2X A;  1YCG A;  2Q0I A;  3FCZ A;  1WUO A;  5KIL A;  1ZKP A;  4RM5 A;  4AWY B;  2M5C A;  5EVK A;  3IEM A;  1JJE A;  2AZ4 A;  2BG7 A;  5FQA A;  4UWS B;  2BG2 A;  4BP0 A;  3KL7 A;  1QH5 A;  1MQO A;  4AD9 A;  4XUK A;  4FEK A;  2GCU A;  3I14 A;  2Q42 A;  1X8G A;  5EVB A;  3WXC A;  2NXA A;  4EYB A;  1K07 A;  2P97 A;  4UWP B;  2BG6 A;  5ACV A;  1WRA A;  2FU9 A;  1WW1 A;  3RPC A;  3SBL A;  4EYF A;  2ZO4 A;  3T9M A;  2Y8B A;  3KNR A;  1L9Y A;  4FR7 A;  4WD6 A;  5ACT A;  3IEL A;  4GYU A;  2CFU A;  1A7T A;  2OHJ A;  2FK6 A;  5EWA A;  2YNW A;  5HH5 A;  4UAM A;  2QDT A;  2OHI A;  2WYM A;  1QH3 A;  1VME A;  3QH8 A;  3ZQ4 A;  5EW0 A;  4AX0 B;  2BMI A;  2FU8 A; 
#chains in the Genus database with same CATH homology
 4C1E A;  2NZF A;  2BG8 A;  1X8H A;  1VGN A;  4HKY A;  2Q9U A;  3ZNB A;  3ADR A;  3BK2 A;  5B3R A;  4GYQ A;  3SPU A;  5A5Z A;  4EYL A;  2HB9 A;  3LVZ A;  4NQ2 A;  2BFL A;  3JXP A;  4TZF A;  1KO2 A;  5HIP A;  1Y44 A;  4NQ6 A;  3DHB A;  4D1W A;  4DIK A;  2GFK A;  3VQZ A;  3ZWF A;  4TYT A;  2FM6 A;  5B1U A;  4HL2 A;  5EVD A;  2BTN A;  2FU7 A;  5LCH A;  4O98 A;  2CBN A;  3AJ3 A;  4BZ3 A;  2GFJ A;  4EFZ A;  1ZTC A;  2WHG A;  4DIL A;  4D1U A;  3X30 A;  4NQ5 A;  3T3O A;  5AHR A;  3MD7 A;  3DH8 A;  2GKL A;  2WRS A;  5LE1 A;  3I15 A;  3PY5 A;  5HH6 A;  3G1P A;  3SRX A;  5IQK A;  2Q0J A;  4P62 A;  4C1F A;  4YSB A;  2YZ3 A;  2ZZI A;  4C1G A;  1XM8 A;  2DOO A;  5DPX A;  4ZO3 A;  3IE0 A;  4GCW A;  5FQB A;  2BFZ B;  2QJS A;  5ACX A;  4H0D A;  4ZEJ A;  3IDZ A;  2BIB A;  2I7T A;  2ZWR A;  3F9O A;  5HIS A;  2P4Z A;  2WYM C;  1KO3 A;  1DDK A;  1JJT A;  2A7M A;  4F6H A;  4RL2 A;  5K0W A;  1A8T A;  3A4Y A;  3IOF A;  3ESH A;  5AXR A;  1BMC A;  5LM6 A;  1WUP A;  3IE1 A;  4Z67 A;  4PVT A;  4UWR B;  2XR1 A;  5EV6 A;  4EXS A;  5KIK A;  4D02 A;  2VW8 A;  4Z5Y A;  5LS3 A;  4C1H A;  4TZ9 A;  1X8I A;  3BC2 A;  2AIO A;  3T3N A;  1DXK A;  4FSB A;  4F6Z A;  3FAI A;  4ZNB A;  3AF6 A;  4CHL A;  1P9E A;  2I7X A;  2BGA A;  5ACP A;  2YCB A;  2M5D A;  5AXO A;  5LSC A;  5EH9 A;  3X2X A;  4RL0 A;  4J5F A;  4Z7R A;  3DHC A;  3RKK A;  4Z5Z A;  3S0Z A;  3I11 A;  4C1C A;  4HL1 A;  4TYF A;  4EY2 A;  2I7V A;  5LCA A;  2QIN A;  3X2Z A;  4V0H A;  3IOG A;  3RKJ A;  1HLK A;  1BVT A;  4RAW A;  2BFZ A;  2FHX A;  5FQC A;  1YCH A;  5EHT A;  4RBS A;  4UWO B;  3BK1 A;  1JT1 A;  4B87 A;  4JO0 A;  3VPE A;  4RAM A;  1E5D A;  2OHH A;  4KEP A;  2H6A A;  4XWT A;  4PVO A;  5LLD A;  2WYL A;  3I13 A;  1KR3 A;  5A0V A;  2DKF A;  2YNU A;  2BFK A;  4XWW A;  5K4M A;  2YNV B;  2P1E A;  3Q6V A;  1SML A;  4J5H A;  2FHX B;  4C1D A;  2Y8A A;  4YSL A;  2Y87 A;  4ZO2 A;  3ZR9 A;  2QDS A;  1VJN A;  3AF5 A;  2ZNB A;  4Z60 A;  2E7Y A;  3DHA A;  4KEQ A;  5LCF A;  4UBQ A;  4AWZ A;  3R2U A;  3SW3 A;  5EV8 A;  2BC2 A;  4Z6X A;  3PG4 A;  5ACR A;  4D1V A;  3H3E A;  2GMN A;  1DD6 A;  5HIQ A;  1XTO A;  3X2Y A;  4D1T A;  2QED A;  5LMC A;  2UYX A;  5ACQ A;  3I0V A;  1ZNB A;  4NQ4 A;  2NYP A;  5AYA A;  2YNT A;  5A87 A;  5AHO A;  1YCF A;  3TP9 A;  5A0T A;  3SFP A;  5ACS A;  2P18 A;  4TZE A;  5K4K A;  2FU6 A;  2NZE A;  5HH4 A;  3IE2 A;  3SD9 A;  5ACW A;  3PY6 A;  3BV6 A;  4C09 A;  1BC2 A;  3KNS A;  5ACU A;  4LE6 A;  4UA4 A;  2R2D A;  3IEK A;  2XF4 A;  4U4L A;  4TZB A;  2YNT B;  5K4N A;  4EXY A;  4YSK A;  2BR6 A;  5AEB A;  2BG8 B;  3P2U A;  2YNV A;  3L6N A;  5B15 A;  4AX1 B;  5HIO A;  1M2X A;  1YCG A;  2Q0I A;  3FCZ A;  1WUO A;  5KIL A;  1ZKP A;  4RM5 A;  4AWY B;  2M5C A;  5EVK A;  3IEM A;  1JJE A;  2AZ4 A;  2BG7 A;  5FQA A;  4UWS B;  2BG2 A;  4BP0 A;  3KL7 A;  1QH5 A;  1MQO A;  4AD9 A;  4XUK A;  4FEK A;  2GCU A;  3I14 A;  2Q42 A;  1X8G A;  5EVB A;  3WXC A;  2NXA A;  4EYB A;  1K07 A;  2P97 A;  4UWP B;  2BG6 A;  5ACV A;  1WRA A;  2FU9 A;  1WW1 A;  3RPC A;  3SBL A;  4EYF A;  2ZO4 A;  3T9M A;  2Y8B A;  3KNR A;  1L9Y A;  4FR7 A;  4WD6 A;  5ACT A;  3IEL A;  4GYU A;  1A7T A;  2OHJ A;  2FK6 A;  5EWA A;  2YNW A;  5HH5 A;  4UAM A;  2QDT A;  2OHI A;  2WYM A;  1QH3 A;  1VME A;  3QH8 A;  3ZQ4 A;  5EW0 A;  4AX0 B;  2BMI A;  2FU8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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