5ACWA

Vim-2-1, discovery of novel inhibitor scaffolds against the metallo- beta-lactamase vim-2 by spr based fragment screening
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
233
structure length
232
Chain Sequence
GEYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNRS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Pseudomonas aeruginosa
publication title Discovery of Novel Inhibitor Scaffolds Against the Metallo-Beta-Lactamase Vim-2 by Spr Based Fragment Screening
pubmed doi rcsb
molecule keywords BETA-LACTAMASE
total genus 73
structure length 232
sequence length 233
chains with identical sequence B
ec nomenclature ec 3.5.2.6: Beta-lactamase.
pdb deposition date 2015-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5acwA00
2E7YA 3SW3A 3T3OA 2QEDA 4GYUA 2BC2A 2Y8AA 3Q6VA 3RKKA 2YZ3A 1JT1A 2YNTB 3IE0A 5HH4A 2BMIA 4Z60A 4TZEA 3VPEA 5EV8A 2I7TA 5LS3A 2GFKA 2A7MA 3G1PA 3KNSA 4Z67A 1DXKA 3L6NA 2H6AA 2FU8A 2BR6A 3PG4A 2FHXA 4HL1A 3S0ZA 1ZTCA 4C1EA 1K07A 5KIKA 4AWZA 1Y44A 4O98A 4EYFA 2R2DA 2M5DA 3ZR9A 5AHOA 2P97A 2WYMA 5A0VA 1WW1A 5LCFA 1XTOA 3IELA 3PY5A 2BFZB 4RAWA 4U4LA 1YCGA 4C1GA 1MQOA 4NQ2A 5AXOA 3BV6A 3X30A 5EVBA 5EVKA 3DHBA 3IOFA 2Y8BA 4KEPA 4DILA 2NYPA 3I0VA 4UAMA 2BFLA 2GCUA 2OHHA 4XUKA 4F6ZA 5HIPA 4D02A 2QINA 2OHIA 3AF5A 3H3EA 2YNUA 4AWYB 1BC2A 4YSKA 2VW8A 5ACUA 4GYQA 2GMNA 2WYLA 3X2ZA 1A8TA 5LMCA 3MD7A 4C1DA 5AEBA 2NZFA 2BG6A 3ZNBA 2WHGA 4P62A 1JJTA 4J5HA 1BVTA 3RKJA 5LSCA 4FR7A 4TYTA 4UWOB 4CHLA 2BG7A 5A87A 2GKLA 4UA4A 2AIOA 2BFKA 4XWTA 1X8HA 5DPXA 1X8IA 3DHAA 4V0HA 4EYLA 5LM6A 4EY2A 5LE1A 2FU9A 1HLKA 5HISA 1YCHA 4TYFA 4AD9A 3I14A 2XR1A 3I13A 5K4NA 2FU7A 2BG8B 4Z7RA 2WRSA 4HKYA 4AX0B 1KR3A 3IE2A 3AF6A 5B3RA 5A5ZA 4LE6A 4XWWA 3SPUA 3F9OA 2HB9A 2P18A 3I11A 3VQZA 3LVZA 2Q42A 3JXPA 3ZQ4A 3IOGA 4TZ9A 4RL2A 1ZNBA 1KO2A 1E5DA 2NZEA 2BG2A 4UWRB 4C1HA 5AHRA 1JJEA 3RPCA 4ZO3A 3ESHA 3SFPA 4B87A 4HL2A 1P9EA 3FCZA 2AZ4A 5A0TA 1WUPA 5AYAA 5EV6A 1SMLA 1X8GA 2GFJA 3IEKA 5FQBA 4EFZA 1QH5A 3ZWFA 2QJSA 1WUOA 3SBLA 3IEMA 5ACRA 2BG8A 4D1UA 4Z6XA 4C09A 5IQKA 3R2UA 5ACQA 4ZNBA 4RAMA 2YCBA 4YSBA 5B15A 4F6HA 3DHCA 2YNWA 2ZO4A 4J5FA 5B1UA 2BIBA 1VMEA 5EH9A 5HH5A 5ACTA 1WRAA 5HIOA 1A7TA 2ZZIA 4EXSA 1VJNA 3FAIA 4GCWA 4ZEJA 2YNVB 5K4MA 1DDKA 4WD6A 5KILA 4FSBA 3I15A 1M2XA 4Z5ZA 2FU6A 4BZ3A 4BP0A 3QH8A 4PVTA 2I7VA 5LLDA 5FQCA 2Q0JA 2DOOA 4D1VA 4RBSA 3KL7A 2CBNA 5ACWA 3X2YA 4AX1B 5EW0A 4UWPB 4C1CA 2FM6A 5HIQA 2WYMC 3AJ3A 5FQAA 3X2XA 4PVOA 1DD6A 5ACVA 3BK1A 1YCFA 1ZKPA 5EHTA 3DH8A 2Y87A 2Q0IA 3TP9A 3WXCA 1XM8A 5EWAA 2BGAA 4D1TA 1VGNA 4D1WA 5LCAA 3T3NA 2P4ZA 2ZWRA 2BTNA 3PY6A 2QDSA 4NQ4A 3IDZA 4JO0A 4RL0A 5AXRA 2YNVA 4FEKA 3P2UA 2Q9UA 3BC2A 2XF4A 5K4KA 3KNRA 2DKFA 3SRXA 5LCHA 4NQ5A 4UBQA 4TZFA 1L9YA 2FK6A 2I7XA 2M5CA 2FHXB 4TZBA 5K0WA 3A4YA 2P1EA 2YNTA 3ADRA 4RM5A 3T9MA 2NXAA 4EYBA 1KO3A 3SD9A 4C1FA 2UYXA 4H0DA 4UWSB 4Z5YA 5ACSA 1QH3A 4KEQA 4YSLA 2QDTA 4ZO2A 2ZNBA 4DIKA 5ACPA 1BMCA 3BK2A 5HH6A 5ACXA 4NQ6A 2OHJA 2BFZA 3IE1A 4EXYA 5EVDA
chains in the Genus database with same CATH superfamily
2E7YA 3SW3A 3T3OA 2QEDA 4GYUA 2BC2A 2Y8AA 3Q6VA 3RKKA 2YZ3A 1JT1A 2YNTB 3IE0A 5HH4A 2BMIA 4Z60A 4TZEA 3VPEA 5EV8A 2I7TA 5LS3A 2GFKA 2A7MA 3G1PA 3KNSA 4Z67A 1DXKA 3L6NA 2H6AA 2FU8A 2BR6A 3PG4A 2FHXA 4HL1A 3S0ZA 1ZTCA 4C1EA 1K07A 5KIKA 4AWZA 1Y44A 4O98A 4EYFA 2R2DA 2M5DA 3ZR9A 5AHOA 2P97A 2WYMA 5A0VA 1WW1A 5LCFA 1XTOA 3IELA 3PY5A 2YHEA 2BFZB 4RAWA 4U4LA 1YCGA 4C1GA 1MQOA 4NQ2A 5AXOA 3BV6A 3X30A 5EVBA 5EVKA 3DHBA 3IOFA 2Y8BA 4KEPA 4DILA 2NYPA 3I0VA 4UAMA 2BFLA 2GCUA 2OHHA 4XUKA 4F6ZA 5HIPA 4D02A 2QINA 2OHIA 3AF5A 3H3EA 2YNUA 4AWYB 1BC2A 2CG2A 4YSKA 2VW8A 5ACUA 4GYQA 2GMNA 2WYLA 3X2ZA 4PDXA 1A8TA 5LMCA 3MD7A 4C1DA 5AEBA 2NZFA 2BG6A 3ZNBA 2WHGA 4P62A 1JJTA 4J5HA 1BVTA 3RKJA 5LSCA 4FR7A 4TYTA 4UWOB 4CHLA 2BG7A 5A87A 2GKLA 4UA4A 4AXHA 2AIOA 2BFKA 4XWTA 1X8HA 5DPXA 1X8IA 3DHAA 4V0HA 4EYLA 5A23A 5LM6A 4EY2A 5LE1A 2FU9A 1HLKA 5HISA 1YCHA 4TYFA 4AD9A 3I14A 2XR1A 3I13A 5K4NA 2FU7A 2BG8B 4Z7RA 2WRSA 4HKYA 4AX0B 1KR3A 3IE2A 3AF6A 5B3RA 5A5ZA 4LE6A 4XWWA 3SPUA 3F9OA 2HB9A 2P18A 3I11A 2CFZA 2CFUA 3VQZA 3LVZA 2Q42A 3JXPA 3ZQ4A 3IOGA 4TZ9A 4RL2A 1ZNBA 1KO2A 1E5DA 2NZEA 2BG2A 4UWRB 4C1HA 5AHRA 1JJEA 3RPCA 4ZO3A 3ESHA 3SFPA 4B87A 4HL2A 1P9EA 3FCZA 2AZ4A 5A0TA 1WUPA 5AYAA 5EV6A 1SMLA 1X8GA 2GFJA 3IEKA 5FQBA 4EFZA 1QH5A 3ZWFA 2QJSA 1WUOA 3SBLA 3IEMA 5ACRA 2BG8A 4D1UA 4NURA 4Z6XA 4C09A 5IQKA 3R2UA 5ACQA 4ZNBA 4RAMA 2YCBA 4YSBA 5B15A 4F6HA 3DHCA 2YNWA 2ZO4A 4J5FA 5B1UA 2BIBA 1VMEA 5EH9A 5HH5A 5ACTA 1WRAA 5HIOA 1A7TA 2ZZIA 4EXSA 1VJNA 3FAIA 4GCWA 4ZEJA 2CG3A 2YNVB 5K4MA 1DDKA 4WD6A 5KILA 4FSBA 3I15A 1M2XA 4Z5ZA 2FU6A 4BZ3A 4BP0A 3QH8A 4PVTA 2I7VA 5LLDA 5FQCA 2Q0JA 2DOOA 4D1VA 4RBSA 3KL7A 2CBNA 5ACWA 3X2YA 4AX1B 5EW0A 4UWPB 4C1CA 2FM6A 5HIQA 4AV7A 2WYMC 3AJ3A 5FQAA 3X2XA 4PVOA 1DD6A 5ACVA 3BK1A 1YCFA 1ZKPA 5EHTA 3DH8A 2Y87A 2Q0IA 3TP9A 3WXCA 1XM8A 5EWAA 2BGAA 4D1TA 1VGNA 4D1WA 5LCAA 3T3NA 2P4ZA 2ZWRA 2BTNA 3PY6A 2QDSA 4NQ4A 3IDZA 4JO0A 4RL0A 5AXRA 2YNVA 4FEKA 3P2UA 2Q9UA 3BC2A 2XF4A 5K4KA 5AIJA 3KNRA 2DKFA 3SRXA 5LCHA 4NQ5A 4UBQA 4TZFA 1L9YA 2FK6A 2I7XA 2M5CA 2FHXB 4TZBA 5K0WA 3A4YA 2P1EA 2YNTA 3ADRA 4RM5A 3T9MA 2NXAA 4EYBA 1KO3A 3SD9A 4C1FA 2UYXA 4H0DA 4UWSB 4Z5YA 5ACSA 1QH3A 4KEQA 4YSLA 2QDTA 4ZO2A 5AJLA 2ZNBA 4DIKA 5ACPA 1BMCA 3BK2A 5HH6A 5ACXA 4NQ6A 2OHJA 2BFZA 3IE1A 4EXYA 5EVDA
chains in the Genus database with same CATH topology
2E7YA 3SW3A 3T3OA 2QEDA 4GYUA 2BC2A 2Y8AA 3Q6VA 3RKKA 2YZ3A 1JT1A 2YNTB 3IE0A 5HH4A 2BMIA 4Z60A 4TZEA 3VPEA 5EV8A 2I7TA 5LS3A 2GFKA 2A7MA 3G1PA 3KNSA 4Z67A 1DXKA 3L6NA 2H6AA 2FU8A 2BR6A 3PG4A 2FHXA 4HL1A 3S0ZA 1ZTCA 4C1EA 1K07A 5KIKA 4AWZA 1Y44A 4O98A 4EYFA 2R2DA 2M5DA 3ZR9A 5AHOA 2P97A 2WYMA 5A0VA 1WW1A 5LCFA 1XTOA 3IELA 3PY5A 2BFZB 4RAWA 4U4LA 1YCGA 4C1GA 1MQOA 4NQ2A 5AXOA 3BV6A 3X30A 5EVBA 5EVKA 3DHBA 3IOFA 2Y8BA 4KEPA 4DILA 2NYPA 3I0VA 4UAMA 2BFLA 2GCUA 2OHHA 4XUKA 4F6ZA 5HIPA 4D02A 2QINA 2OHIA 3AF5A 3H3EA 2YNUA 4AWYB 1BC2A 4YSKA 2VW8A 5ACUA 4GYQA 2GMNA 2WYLA 3X2ZA 1A8TA 5LMCA 3MD7A 4C1DA 5AEBA 2NZFA 2BG6A 3ZNBA 2WHGA 4P62A 1JJTA 4J5HA 1BVTA 3RKJA 5LSCA 4FR7A 4TYTA 4UWOB 4CHLA 2BG7A 5A87A 2GKLA 4UA4A 2AIOA 2BFKA 4XWTA 1X8HA 5DPXA 1X8IA 3DHAA 4V0HA 4EYLA 5LM6A 4EY2A 5LE1A 2FU9A 1HLKA 5HISA 1YCHA 4TYFA 4AD9A 3I14A 2XR1A 3I13A 5K4NA 2FU7A 2BG8B 4Z7RA 2WRSA 4HKYA 4AX0B 1KR3A 3IE2A 3AF6A 5B3RA 5A5ZA 4LE6A 4XWWA 3SPUA 3F9OA 2HB9A 2P18A 3I11A 3VQZA 3LVZA 2Q42A 3JXPA 3ZQ4A 3IOGA 4TZ9A 4RL2A 1ZNBA 1KO2A 1E5DA 2NZEA 2BG2A 4UWRB 4C1HA 5AHRA 1JJEA 3RPCA 4ZO3A 3ESHA 3SFPA 4B87A 4HL2A 1P9EA 3FCZA 2AZ4A 5A0TA 1WUPA 5AYAA 5EV6A 1SMLA 1X8GA 2GFJA 3IEKA 5FQBA 4EFZA 1QH5A 3ZWFA 2QJSA 1WUOA 3SBLA 3IEMA 5ACRA 2BG8A 4D1UA 4Z6XA 4C09A 5IQKA 3R2UA 5ACQA 4ZNBA 4RAMA 2YCBA 4YSBA 5B15A 4F6HA 3DHCA 2YNWA 2ZO4A 4J5FA 5B1UA 2BIBA 1VMEA 5EH9A 5HH5A 5ACTA 1WRAA 5HIOA 1A7TA 2ZZIA 4EXSA 1VJNA 3FAIA 4GCWA 4ZEJA 2YNVB 5K4MA 1DDKA 4WD6A 5KILA 4FSBA 3I15A 1M2XA 4Z5ZA 2FU6A 4BZ3A 4BP0A 3QH8A 4PVTA 2I7VA 5LLDA 5FQCA 2Q0JA 2DOOA 4D1VA 4RBSA 3KL7A 2CBNA 5ACWA 3X2YA 4AX1B 5EW0A 4UWPB 4C1CA 2FM6A 5HIQA 2WYMC 3AJ3A 5FQAA 3X2XA 4PVOA 1DD6A 5ACVA 3BK1A 1YCFA 1ZKPA 5EHTA 3DH8A 2Y87A 2Q0IA 3TP9A 3WXCA 1XM8A 5EWAA 2BGAA 4D1TA 1VGNA 4D1WA 5LCAA 3T3NA 2P4ZA 2ZWRA 2BTNA 3PY6A 2QDSA 4NQ4A 3IDZA 4JO0A 4RL0A 5AXRA 2YNVA 4FEKA 3P2UA 2Q9UA 3BC2A 2XF4A 5K4KA 3KNRA 2DKFA 3SRXA 5LCHA 4NQ5A 4UBQA 4TZFA 1L9YA 2FK6A 2I7XA 2M5CA 2FHXB 4TZBA 5K0WA 3A4YA 2P1EA 2YNTA 3ADRA 4RM5A 3T9MA 2NXAA 4EYBA 1KO3A 3SD9A 4C1FA 2UYXA 4H0DA 4UWSB 4Z5YA 5ACSA 1QH3A 4KEQA 4YSLA 2QDTA 4ZO2A 2ZNBA 4DIKA 5ACPA 1BMCA 3BK2A 5HH6A 5ACXA 4NQ6A 2OHJA 2BFZA 3IE1A 4EXYA 5EVDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E7Y A;  3SW3 A;  3T3O A;  2QED A;  4GYU A;  2BC2 A;  2Y8A A;  3Q6V A;  3RKK A;  2YZ3 A;  1JT1 A;  2YNT B;  3IE0 A;  5HH4 A;  2BMI A;  4Z60 A;  4TZE A;  3VPE A;  5EV8 A;  2I7T A;  5LS3 A;  2GFK A;  2A7M A;  3G1P A;  3KNS A;  4Z67 A;  1DXK A;  3L6N A;  2H6A A;  2FU8 A;  2BR6 A;  3PG4 A;  2FHX A;  4HL1 A;  3S0Z A;  1ZTC A;  4C1E A;  1K07 A;  5KIK A;  4AWZ A;  1Y44 A;  4O98 A;  4EYF A;  2R2D A;  2M5D A;  3ZR9 A;  5AHO A;  2P97 A;  2WYM A;  5A0V A;  1WW1 A;  5LCF A;  1XTO A;  3IEL A;  3PY5 A;  2BFZ B;  4RAW A;  4U4L A;  1YCG A;  4C1G A;  1MQO A;  4NQ2 A;  5AXO A;  3BV6 A;  3X30 A;  5EVB A;  5EVK A;  3DHB A;  3IOF A;  2Y8B A;  4KEP A;  4DIL A;  2NYP A;  3I0V A;  4UAM A;  2BFL A;  2GCU A;  2OHH A;  4XUK A;  4F6Z A;  5HIP A;  4D02 A;  2QIN A;  2OHI A;  3AF5 A;  3H3E A;  2YNU A;  4AWY B;  1BC2 A;  4YSK A;  2VW8 A;  5ACU A;  4GYQ A;  2GMN A;  2WYL A;  3X2Z A;  1A8T A;  5LMC A;  3MD7 A;  4C1D A;  5AEB A;  2NZF A;  2BG6 A;  3ZNB A;  2WHG A;  4P62 A;  1JJT A;  4J5H A;  1BVT A;  3RKJ A;  5LSC A;  4FR7 A;  4TYT A;  4UWO B;  4CHL A;  2BG7 A;  5A87 A;  2GKL A;  4UA4 A;  2AIO A;  2BFK A;  4XWT A;  1X8H A;  5DPX A;  1X8I A;  3DHA A;  4V0H A;  4EYL A;  5LM6 A;  4EY2 A;  5LE1 A;  2FU9 A;  1HLK A;  5HIS A;  1YCH A;  4TYF A;  4AD9 A;  3I14 A;  2XR1 A;  3I13 A;  5K4N A;  2FU7 A;  2BG8 B;  4Z7R A;  2WRS A;  4HKY A;  4AX0 B;  1KR3 A;  3IE2 A;  3AF6 A;  5B3R A;  5A5Z A;  4LE6 A;  4XWW A;  3SPU A;  3F9O A;  2HB9 A;  2P18 A;  3I11 A;  3VQZ A;  3LVZ A;  2Q42 A;  3JXP A;  3ZQ4 A;  3IOG A;  4TZ9 A;  4RL2 A;  1ZNB A;  1KO2 A;  1E5D A;  2NZE A;  2BG2 A;  4UWR B;  4C1H A;  5AHR A;  1JJE A;  3RPC A;  4ZO3 A;  3ESH A;  3SFP A;  4B87 A;  4HL2 A;  1P9E A;  3FCZ A;  2AZ4 A;  5A0T A;  1WUP A;  5AYA A;  5EV6 A;  1SML A;  1X8G A;  2GFJ A;  3IEK A;  5FQB A;  4EFZ A;  1QH5 A;  3ZWF A;  2QJS A;  1WUO A;  3SBL A;  3IEM A;  5ACR A;  2BG8 A;  4D1U A;  4Z6X A;  4C09 A;  5IQK A;  3R2U A;  5ACQ A;  4ZNB A;  4RAM A;  2YCB A;  4YSB A;  5B15 A;  4F6H A;  3DHC A;  2YNW A;  2ZO4 A;  4J5F A;  5B1U A;  2BIB A;  1VME A;  5EH9 A;  5HH5 A;  5ACT A;  1WRA A;  5HIO A;  1A7T A;  2ZZI A;  4EXS A;  1VJN A;  3FAI A;  4GCW A;  4ZEJ A;  2YNV B;  5K4M A;  1DDK A;  4WD6 A;  5KIL A;  4FSB A;  3I15 A;  1M2X A;  4Z5Z A;  2FU6 A;  4BZ3 A;  4BP0 A;  3QH8 A;  4PVT A;  2I7V A;  5LLD A;  5FQC A;  2Q0J A;  2DOO A;  4D1V A;  4RBS A;  3KL7 A;  2CBN A;  5ACW A;  3X2Y A;  4AX1 B;  5EW0 A;  4UWP B;  4C1C A;  2FM6 A;  5HIQ A;  2WYM C;  3AJ3 A;  5FQA A;  3X2X A;  4PVO A;  1DD6 A;  5ACV A;  3BK1 A;  1YCF A;  1ZKP A;  5EHT A;  3DH8 A;  2Y87 A;  2Q0I A;  3TP9 A;  3WXC A;  1XM8 A;  5EWA A;  2BGA A;  4D1T A;  1VGN A;  4D1W A;  5LCA A;  3T3N A;  2P4Z A;  2ZWR A;  2BTN A;  3PY6 A;  2QDS A;  4NQ4 A;  3IDZ A;  4JO0 A;  4RL0 A;  5AXR A;  2YNV A;  4FEK A;  3P2U A;  2Q9U A;  3BC2 A;  2XF4 A;  5K4K A;  3KNR A;  2DKF A;  3SRX A;  5LCH A;  4NQ5 A;  4UBQ A;  4TZF A;  1L9Y A;  2FK6 A;  2I7X A;  2M5C A;  2FHX B;  4TZB A;  5K0W A;  3A4Y A;  2P1E A;  2YNT A;  3ADR A;  4RM5 A;  3T9M A;  2NXA A;  4EYB A;  1KO3 A;  3SD9 A;  4C1F A;  2UYX A;  4H0D A;  4UWS B;  4Z5Y A;  5ACS A;  1QH3 A;  4KEQ A;  4YSL A;  2QDT A;  4ZO2 A;  2ZNB A;  4DIK A;  5ACP A;  1BMC A;  3BK2 A;  5HH6 A;  5ACX A;  4NQ6 A;  2OHJ A;  2BFZ A;  3IE1 A;  4EXY A;  5EVD A; 
#chains in the Genus database with same CATH topology
 2E7Y A;  3SW3 A;  3T3O A;  2QED A;  4GYU A;  2BC2 A;  2Y8A A;  3Q6V A;  3RKK A;  2YZ3 A;  1JT1 A;  2YNT B;  3IE0 A;  5HH4 A;  2BMI A;  4Z60 A;  4TZE A;  3VPE A;  5EV8 A;  2I7T A;  5LS3 A;  2GFK A;  2A7M A;  3G1P A;  3KNS A;  4Z67 A;  1DXK A;  3L6N A;  2H6A A;  2FU8 A;  2BR6 A;  3PG4 A;  2FHX A;  4HL1 A;  3S0Z A;  1ZTC A;  4C1E A;  1K07 A;  5KIK A;  4AWZ A;  1Y44 A;  4O98 A;  4EYF A;  2R2D A;  2M5D A;  3ZR9 A;  5AHO A;  2P97 A;  2WYM A;  5A0V A;  1WW1 A;  5LCF A;  1XTO A;  3IEL A;  3PY5 A;  2YHE A;  2BFZ B;  4RAW A;  4U4L A;  1YCG A;  4C1G A;  1MQO A;  4NQ2 A;  5AXO A;  3BV6 A;  3X30 A;  5EVB A;  5EVK A;  3DHB A;  3IOF A;  2Y8B A;  4KEP A;  4DIL A;  2NYP A;  3I0V A;  4UAM A;  2BFL A;  2GCU A;  2OHH A;  4XUK A;  4F6Z A;  5HIP A;  4D02 A;  2QIN A;  2OHI A;  3AF5 A;  3H3E A;  2YNU A;  4AWY B;  1BC2 A;  2CG2 A;  4YSK A;  2VW8 A;  5ACU A;  4GYQ A;  2GMN A;  2WYL A;  3X2Z A;  4PDX A;  1A8T A;  5LMC A;  3MD7 A;  4C1D A;  5AEB A;  2NZF A;  2BG6 A;  3ZNB A;  2WHG A;  4P62 A;  1JJT A;  4J5H A;  1BVT A;  3RKJ A;  5LSC A;  4FR7 A;  4TYT A;  4UWO B;  4CHL A;  2BG7 A;  5A87 A;  2GKL A;  4UA4 A;  4AXH A;  2AIO A;  2BFK A;  4XWT A;  1X8H A;  5DPX A;  1X8I A;  3DHA A;  4V0H A;  4EYL A;  5A23 A;  5LM6 A;  4EY2 A;  5LE1 A;  2FU9 A;  1HLK A;  5HIS A;  1YCH A;  4TYF A;  4AD9 A;  3I14 A;  2XR1 A;  3I13 A;  5K4N A;  2FU7 A;  2BG8 B;  4Z7R A;  2WRS A;  4HKY A;  4AX0 B;  1KR3 A;  3IE2 A;  3AF6 A;  5B3R A;  5A5Z A;  4LE6 A;  4XWW A;  3SPU A;  3F9O A;  2HB9 A;  2P18 A;  3I11 A;  2CFZ A;  2CFU A;  3VQZ A;  3LVZ A;  2Q42 A;  3JXP A;  3ZQ4 A;  3IOG A;  4TZ9 A;  4RL2 A;  1ZNB A;  1KO2 A;  1E5D A;  2NZE A;  2BG2 A;  4UWR B;  4C1H A;  5AHR A;  1JJE A;  3RPC A;  4ZO3 A;  3ESH A;  3SFP A;  4B87 A;  4HL2 A;  1P9E A;  3FCZ A;  2AZ4 A;  5A0T A;  1WUP A;  5AYA A;  5EV6 A;  1SML A;  1X8G A;  2GFJ A;  3IEK A;  5FQB A;  4EFZ A;  1QH5 A;  3ZWF A;  2QJS A;  1WUO A;  3SBL A;  3IEM A;  5ACR A;  2BG8 A;  4D1U A;  4NUR A;  4Z6X A;  4C09 A;  5IQK A;  3R2U A;  5ACQ A;  4ZNB A;  4RAM A;  2YCB A;  4YSB A;  5B15 A;  4F6H A;  3DHC A;  2YNW A;  2ZO4 A;  4J5F A;  5B1U A;  2BIB A;  1VME A;  5EH9 A;  5HH5 A;  5ACT A;  1WRA A;  5HIO A;  1A7T A;  2ZZI A;  4EXS A;  1VJN A;  3FAI A;  4GCW A;  4ZEJ A;  2CG3 A;  2YNV B;  5K4M A;  1DDK A;  4WD6 A;  5KIL A;  4FSB A;  3I15 A;  1M2X A;  4Z5Z A;  2FU6 A;  4BZ3 A;  4BP0 A;  3QH8 A;  4PVT A;  2I7V A;  5LLD A;  5FQC A;  2Q0J A;  2DOO A;  4D1V A;  4RBS A;  3KL7 A;  2CBN A;  5ACW A;  3X2Y A;  4AX1 B;  5EW0 A;  4UWP B;  4C1C A;  2FM6 A;  5HIQ A;  4AV7 A;  2WYM C;  3AJ3 A;  5FQA A;  3X2X A;  4PVO A;  1DD6 A;  5ACV A;  3BK1 A;  1YCF A;  1ZKP A;  5EHT A;  3DH8 A;  2Y87 A;  2Q0I A;  3TP9 A;  3WXC A;  1XM8 A;  5EWA A;  2BGA A;  4D1T A;  1VGN A;  4D1W A;  5LCA A;  3T3N A;  2P4Z A;  2ZWR A;  2BTN A;  3PY6 A;  2QDS A;  4NQ4 A;  3IDZ A;  4JO0 A;  4RL0 A;  5AXR A;  2YNV A;  4FEK A;  3P2U A;  2Q9U A;  3BC2 A;  2XF4 A;  5K4K A;  5AIJ A;  3KNR A;  2DKF A;  3SRX A;  5LCH A;  4NQ5 A;  4UBQ A;  4TZF A;  1L9Y A;  2FK6 A;  2I7X A;  2M5C A;  2FHX B;  4TZB A;  5K0W A;  3A4Y A;  2P1E A;  2YNT A;  3ADR A;  4RM5 A;  3T9M A;  2NXA A;  4EYB A;  1KO3 A;  3SD9 A;  4C1F A;  2UYX A;  4H0D A;  4UWS B;  4Z5Y A;  5ACS A;  1QH3 A;  4KEQ A;  4YSL A;  2QDT A;  4ZO2 A;  5AJL A;  2ZNB A;  4DIK A;  5ACP A;  1BMC A;  3BK2 A;  5HH6 A;  5ACX A;  4NQ6 A;  2OHJ A;  2BFZ A;  3IE1 A;  4EXY A;  5EVD A; 
#chains in the Genus database with same CATH homology
 2E7Y A;  3SW3 A;  3T3O A;  2QED A;  4GYU A;  2BC2 A;  2Y8A A;  3Q6V A;  3RKK A;  2YZ3 A;  1JT1 A;  2YNT B;  3IE0 A;  5HH4 A;  2BMI A;  4Z60 A;  4TZE A;  3VPE A;  5EV8 A;  2I7T A;  5LS3 A;  2GFK A;  2A7M A;  3G1P A;  3KNS A;  4Z67 A;  1DXK A;  3L6N A;  2H6A A;  2FU8 A;  2BR6 A;  3PG4 A;  2FHX A;  4HL1 A;  3S0Z A;  1ZTC A;  4C1E A;  1K07 A;  5KIK A;  4AWZ A;  1Y44 A;  4O98 A;  4EYF A;  2R2D A;  2M5D A;  3ZR9 A;  5AHO A;  2P97 A;  2WYM A;  5A0V A;  1WW1 A;  5LCF A;  1XTO A;  3IEL A;  3PY5 A;  2BFZ B;  4RAW A;  4U4L A;  1YCG A;  4C1G A;  1MQO A;  4NQ2 A;  5AXO A;  3BV6 A;  3X30 A;  5EVB A;  5EVK A;  3DHB A;  3IOF A;  2Y8B A;  4KEP A;  4DIL A;  2NYP A;  3I0V A;  4UAM A;  2BFL A;  2GCU A;  2OHH A;  4XUK A;  4F6Z A;  5HIP A;  4D02 A;  2QIN A;  2OHI A;  3AF5 A;  3H3E A;  2YNU A;  4AWY B;  1BC2 A;  4YSK A;  2VW8 A;  5ACU A;  4GYQ A;  2GMN A;  2WYL A;  3X2Z A;  1A8T A;  5LMC A;  3MD7 A;  4C1D A;  5AEB A;  2NZF A;  2BG6 A;  3ZNB A;  2WHG A;  4P62 A;  1JJT A;  4J5H A;  1BVT A;  3RKJ A;  5LSC A;  4FR7 A;  4TYT A;  4UWO B;  4CHL A;  2BG7 A;  5A87 A;  2GKL A;  4UA4 A;  2AIO A;  2BFK A;  4XWT A;  1X8H A;  5DPX A;  1X8I A;  3DHA A;  4V0H A;  4EYL A;  5LM6 A;  4EY2 A;  5LE1 A;  2FU9 A;  1HLK A;  5HIS A;  1YCH A;  4TYF A;  4AD9 A;  3I14 A;  2XR1 A;  3I13 A;  5K4N A;  2FU7 A;  2BG8 B;  4Z7R A;  2WRS A;  4HKY A;  4AX0 B;  1KR3 A;  3IE2 A;  3AF6 A;  5B3R A;  5A5Z A;  4LE6 A;  4XWW A;  3SPU A;  3F9O A;  2HB9 A;  2P18 A;  3I11 A;  3VQZ A;  3LVZ A;  2Q42 A;  3JXP A;  3ZQ4 A;  3IOG A;  4TZ9 A;  4RL2 A;  1ZNB A;  1KO2 A;  1E5D A;  2NZE A;  2BG2 A;  4UWR B;  4C1H A;  5AHR A;  1JJE A;  3RPC A;  4ZO3 A;  3ESH A;  3SFP A;  4B87 A;  4HL2 A;  1P9E A;  3FCZ A;  2AZ4 A;  5A0T A;  1WUP A;  5AYA A;  5EV6 A;  1SML A;  1X8G A;  2GFJ A;  3IEK A;  5FQB A;  4EFZ A;  1QH5 A;  3ZWF A;  2QJS A;  1WUO A;  3SBL A;  3IEM A;  5ACR A;  2BG8 A;  4D1U A;  4Z6X A;  4C09 A;  5IQK A;  3R2U A;  5ACQ A;  4ZNB A;  4RAM A;  2YCB A;  4YSB A;  5B15 A;  4F6H A;  3DHC A;  2YNW A;  2ZO4 A;  4J5F A;  5B1U A;  2BIB A;  1VME A;  5EH9 A;  5HH5 A;  5ACT A;  1WRA A;  5HIO A;  1A7T A;  2ZZI A;  4EXS A;  1VJN A;  3FAI A;  4GCW A;  4ZEJ A;  2YNV B;  5K4M A;  1DDK A;  4WD6 A;  5KIL A;  4FSB A;  3I15 A;  1M2X A;  4Z5Z A;  2FU6 A;  4BZ3 A;  4BP0 A;  3QH8 A;  4PVT A;  2I7V A;  5LLD A;  5FQC A;  2Q0J A;  2DOO A;  4D1V A;  4RBS A;  3KL7 A;  2CBN A;  5ACW A;  3X2Y A;  4AX1 B;  5EW0 A;  4UWP B;  4C1C A;  2FM6 A;  5HIQ A;  2WYM C;  3AJ3 A;  5FQA A;  3X2X A;  4PVO A;  1DD6 A;  5ACV A;  3BK1 A;  1YCF A;  1ZKP A;  5EHT A;  3DH8 A;  2Y87 A;  2Q0I A;  3TP9 A;  3WXC A;  1XM8 A;  5EWA A;  2BGA A;  4D1T A;  1VGN A;  4D1W A;  5LCA A;  3T3N A;  2P4Z A;  2ZWR A;  2BTN A;  3PY6 A;  2QDS A;  4NQ4 A;  3IDZ A;  4JO0 A;  4RL0 A;  5AXR A;  2YNV A;  4FEK A;  3P2U A;  2Q9U A;  3BC2 A;  2XF4 A;  5K4K A;  3KNR A;  2DKF A;  3SRX A;  5LCH A;  4NQ5 A;  4UBQ A;  4TZF A;  1L9Y A;  2FK6 A;  2I7X A;  2M5C A;  2FHX B;  4TZB A;  5K0W A;  3A4Y A;  2P1E A;  2YNT A;  3ADR A;  4RM5 A;  3T9M A;  2NXA A;  4EYB A;  1KO3 A;  3SD9 A;  4C1F A;  2UYX A;  4H0D A;  4UWS B;  4Z5Y A;  5ACS A;  1QH3 A;  4KEQ A;  4YSL A;  2QDT A;  4ZO2 A;  2ZNB A;  4DIK A;  5ACP A;  1BMC A;  3BK2 A;  5HH6 A;  5ACX A;  4NQ6 A;  2OHJ A;  2BFZ A;  3IE1 A;  4EXY A;  5EVD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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