5ACXA

Vim-2-2, discovery of novel inhibitor scaffolds against the metallo- beta-lactamase vim-2 by spr based fragment screening
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
233
structure length
231
Chain Sequence
GEYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGAIYELSTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNRS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of Novel Inhibitor Scaffolds Against the Metallo-Beta-Lactamase Vim-2 by Spr Based Fragment Screening
pubmed doi rcsb
molecule tags Hydrolase
source organism Pseudomonas aeruginosa
molecule keywords BETA-LACTAMASE
total genus 77
structure length 231
sequence length 233
chains with identical sequence B
ec nomenclature ec 3.5.2.6: Beta-lactamase.
pdb deposition date 2015-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5acxA00
4D1TA 4DIKA 1L9YA 2GKLA 3A4YA 1A8TA 1HLKA 3T3NA 4ZO3A 1QH5A 2FU9A 4GYQA 3ZR9A 3VQZA 2Q0IA 5EVBA 4TYTA 4Z5YA 3I15A 5EVKA 2I7TA 1SMLA 2P18A 3IEKA 3H3EA 1P9EA 4TZBA 5HH4A 3IE0A 2I7XA 4NQ6A 3ESHA 5KILA 4PVTA 4AX1B 2CBNA 3F9OA 2M5DA 3IE1A 3PY5A 3I11A 4Z6XA 1BVTA 1DXKA 5LCAA 3BK2A 3ZQ4A 2QEDA 4UWPB 3BK1A 1A7TA 4UWRB 5ACUA 2E7YA 2BG8A 1JJTA 4GCWA 5LLDA 4YSBA 5HIOA 2FU7A 5IQKA 2AZ4A 2Q0JA 4D1VA 3IOFA 4BP0A 5ACVA 5AEBA 5HIPA 5LCFA 4AX0B 2Q42A 5HH6A 3AJ3A 5LS3A 1X8HA 5EWAA 1YCGA 4HL2A 1VGNA 2QINA 1WUOA 1JT1A 5KIKA 4CHLA 2BG7A 4UBQA 4P62A 2H6AA 2FK6A 3DHCA 5EVDA 4J5FA 5ACQA 4PVOA 5LE1A 1ZNBA 2Y8AA 3T9MA 2Y8BA 4C1DA 1WUPA 4WD6A 1X8GA 5EW0A 4C1FA 4TZ9A 3RKKA 4ZO2A 1XTOA 4F6HA 2GFJA 1Y44A 4UA4A 3PG4A 4KEQA 3FAIA 3KL7A 4Z60A 5ACRA 5ACPA 3VPEA 2YNVA 5FQAA 2YZ3A 2Y87A 3SRXA 3R2UA 2QDTA 2XF4A 1KR3A 2FU8A 4ZEJA 4TYFA 4Z5ZA 3QH8A 3AF6A 3WXCA 4EFZA 5K4NA 5A87A 4C1EA 3SFPA 3L6NA 4NQ4A 3PY6A 3ZNBA 4BZ3A 2BTNA 2UYXA 4EXSA 3X2XA 4HL1A 4NQ2A 5A5ZA 4O98A 5LMCA 2HB9A 1DDKA 2FHXA 1XM8A 5AXRA 2M5CA 3KNSA 5AHOA 3S0ZA 4GYUA 3IE2A 5B15A 3TP9A 3RKJA 5FQCA 4C09A 2P4ZA 5K4KA 1M2XA 2BG2A 2NZEA 3SW3A 2WYLA 2FU6A 2DKFA 2GFKA 4C1CA 4TZEA 3ADRA 1JJEA 1X8IA 2ZNBA 3SBLA 4V0HA 3IEMA 3IOGA 2YNWA 2NYPA 4LE6A 4D02A 4KEPA 2NXAA 1K07A 4EYLA 4JO0A 2BFKA 4HKYA 2WYMA 2OHJA 4RL0A 4FR7A 2P97A 4AD9A 5LCHA 3I13A 5DPXA 2FHXB 5AYAA 2QJSA 2OHHA 4J5HA 5EV6A 4D1UA 5EV8A 5FQBA 2BMIA 3DHAA 4EYBA 5HH5A 2ZO4A 5A0TA 2BG8B 4U4LA 3RPCA 2WRSA 2BGAA 2BIBA 4H0DA 3T3OA 1QH3A 4FSBA 1KO2A 3FCZA 3KNRA 3SD9A 2BFZA 4RBSA 3X30A 5ACTA 4YSLA 4UWOB 3DHBA 2ZWRA 5ACXA 2QDSA 4EYFA 5K0WA 1VJNA 4YSKA 2GCUA 4EXYA 5EH9A 5LSCA 2NZFA 1DD6A 3I14A 5HIQA 3SPUA 4UAMA 2VW8A 1MQOA 4Z7RA 2YNTA 5EHTA 1BC2A 1WRAA 2DOOA 3JXPA 2BFZB 4RAMA 3IDZA 2YNVB 4XWTA 2R2DA 1ZTCA 2BFLA 4AWYB 3AF5A 4AWZA 2OHIA 3P2UA 2WHGA 5K4MA 4RL2A 1BMCA 4RAWA 5AXOA 2YCBA 5HISA 2I7VA 4EY2A 5B1UA 2BC2A 4D1WA 3Q6VA 2ZZIA 1YCFA 4TZFA 1WW1A 3MD7A 2P1EA 4FEKA 5LM6A 2WYMC 2BG6A 2XR1A 2YNTB 5AHRA 5B3RA 3IELA 1KO3A 3I0VA 4C1HA 5ACSA 2YNUA 4NQ5A 4C1GA 4DILA 2AIOA 1E5DA 3LVZA 4XUKA 2A7MA 1ZKPA 2GMNA 4B87A 4RM5A 3X2YA 1VMEA 2BR6A 4ZNBA 4XWWA 3BC2A 3DH8A 3X2ZA 4UWSB 3BV6A 5ACWA 2Q9UA 2FM6A 3ZWFA 4Z67A 4F6ZA 1YCHA 3G1PA 5A0VA
chains in the Genus database with same CATH superfamily
4D1TA 4DIKA 1L9YA 2GKLA 3A4YA 1A8TA 1HLKA 3T3NA 4ZO3A 1QH5A 2FU9A 4GYQA 3ZR9A 3VQZA 2Q0IA 5EVBA 4TYTA 4Z5YA 3I15A 5EVKA 2I7TA 1SMLA 2P18A 3IEKA 3H3EA 1P9EA 4TZBA 5HH4A 3IE0A 2I7XA 4NURA 4NQ6A 3ESHA 5KILA 4PVTA 4AX1B 2CG3A 2CBNA 3F9OA 2M5DA 3IE1A 3PY5A 3I11A 4Z6XA 1BVTA 1DXKA 5LCAA 3BK2A 3ZQ4A 2QEDA 4UWPB 3BK1A 1A7TA 4UWRB 5AIJA 5ACUA 2E7YA 2BG8A 1JJTA 4GCWA 5LLDA 4YSBA 5HIOA 2FU7A 5IQKA 2AZ4A 2Q0JA 4D1VA 2CFUA 3IOFA 4BP0A 5ACVA 5AEBA 5HIPA 5LCFA 4AX0B 2Q42A 5HH6A 3AJ3A 5LS3A 1X8HA 5EWAA 1YCGA 4HL2A 1VGNA 2QINA 1WUOA 1JT1A 5KIKA 4CHLA 2BG7A 4UBQA 4P62A 2H6AA 2FK6A 3DHCA 5EVDA 4J5FA 5ACQA 4PVOA 5LE1A 1ZNBA 2Y8AA 3T9MA 2Y8BA 4C1DA 1WUPA 4WD6A 1X8GA 5EW0A 4C1FA 4TZ9A 3RKKA 4ZO2A 1XTOA 4F6HA 2GFJA 1Y44A 4UA4A 3PG4A 4KEQA 3FAIA 3KL7A 4Z60A 5ACRA 5ACPA 3VPEA 2YNVA 5FQAA 4AXHA 2YZ3A 2Y87A 3SRXA 3R2UA 2QDTA 2XF4A 1KR3A 2FU8A 4ZEJA 4TYFA 4Z5ZA 3QH8A 3AF6A 3WXCA 4EFZA 5K4NA 5A87A 4C1EA 3SFPA 3L6NA 4NQ4A 3PY6A 3ZNBA 4BZ3A 2BTNA 2UYXA 4EXSA 3X2XA 4HL1A 4NQ2A 5A5ZA 4O98A 5LMCA 2HB9A 1DDKA 2FHXA 1XM8A 5AXRA 2M5CA 3KNSA 5AHOA 3S0ZA 4GYUA 3IE2A 5B15A 3TP9A 3RKJA 5FQCA 4C09A 2P4ZA 5K4KA 1M2XA 2BG2A 2NZEA 3SW3A 2WYLA 2FU6A 2DKFA 2GFKA 4C1CA 4TZEA 3ADRA 1JJEA 1X8IA 2ZNBA 3SBLA 4V0HA 3IEMA 3IOGA 2YNWA 2NYPA 4LE6A 4KEPA 4D02A 2NXAA 1K07A 4EYLA 4JO0A 2BFKA 4HKYA 2WYMA 2OHJA 4RL0A 5AJLA 4FR7A 2P97A 4AD9A 5LCHA 3I13A 5DPXA 2FHXB 5AYAA 2QJSA 2OHHA 4J5HA 5EV6A 4D1UA 5EV8A 5FQBA 2BMIA 2CG2A 3DHAA 4EYBA 2YHEA 5HH5A 2ZO4A 5A0TA 2BG8B 4U4LA 3RPCA 2WRSA 2BGAA 2BIBA 4H0DA 3T3OA 1QH3A 2CFZA 4FSBA 1KO2A 3FCZA 3KNRA 3SD9A 2BFZA 4RBSA 3X30A 5ACTA 4YSLA 4UWOB 3DHBA 2ZWRA 5ACXA 2QDSA 4PDXA 4EYFA 5K0WA 1VJNA 4YSKA 2GCUA 4EXYA 5EH9A 5LSCA 2NZFA 4AV7A 1DD6A 3I14A 5HIQA 3SPUA 4UAMA 2VW8A 1MQOA 4Z7RA 2YNTA 5EHTA 1BC2A 1WRAA 2DOOA 3JXPA 2BFZB 4RAMA 3IDZA 2YNVB 4XWTA 2R2DA 1ZTCA 2BFLA 4AWYB 3AF5A 4AWZA 2OHIA 3P2UA 2WHGA 5K4MA 4RL2A 1BMCA 4RAWA 5AXOA 2YCBA 5HISA 2I7VA 4EY2A 5B1UA 2BC2A 4D1WA 3Q6VA 2ZZIA 1YCFA 4TZFA 1WW1A 3MD7A 2P1EA 4FEKA 5LM6A 5A23A 2WYMC 2BG6A 2XR1A 2YNTB 5AHRA 5B3RA 3IELA 1KO3A 3I0VA 4C1HA 5ACSA 2YNUA 4NQ5A 4C1GA 4DILA 2AIOA 1E5DA 3LVZA 4XUKA 2A7MA 1ZKPA 2GMNA 4B87A 4RM5A 3X2YA 1VMEA 2BR6A 4ZNBA 4XWWA 3BC2A 3DH8A 3X2ZA 4UWSB 3BV6A 5ACWA 2Q9UA 2FM6A 3ZWFA 4Z67A 4F6ZA 1YCHA 3G1PA 5A0VA
chains in the Genus database with same CATH topology
4D1TA 4DIKA 1L9YA 2GKLA 3A4YA 1A8TA 1HLKA 3T3NA 4ZO3A 1QH5A 2FU9A 4GYQA 3ZR9A 3VQZA 2Q0IA 5EVBA 4TYTA 4Z5YA 3I15A 5EVKA 2I7TA 1SMLA 2P18A 3IEKA 3H3EA 1P9EA 4TZBA 5HH4A 3IE0A 2I7XA 4NQ6A 3ESHA 5KILA 4PVTA 4AX1B 2CBNA 3F9OA 2M5DA 3IE1A 3PY5A 3I11A 4Z6XA 1BVTA 1DXKA 5LCAA 3BK2A 3ZQ4A 2QEDA 4UWPB 3BK1A 1A7TA 4UWRB 5ACUA 2E7YA 2BG8A 1JJTA 4GCWA 5LLDA 4YSBA 5HIOA 2FU7A 5IQKA 2AZ4A 2Q0JA 4D1VA 3IOFA 4BP0A 5ACVA 5AEBA 5HIPA 5LCFA 4AX0B 2Q42A 5HH6A 3AJ3A 5LS3A 1X8HA 5EWAA 1YCGA 4HL2A 1VGNA 2QINA 1WUOA 1JT1A 5KIKA 4CHLA 2BG7A 4UBQA 4P62A 2H6AA 2FK6A 3DHCA 5EVDA 4J5FA 5ACQA 4PVOA 5LE1A 1ZNBA 2Y8AA 3T9MA 2Y8BA 4C1DA 1WUPA 4WD6A 1X8GA 5EW0A 4C1FA 4TZ9A 3RKKA 4ZO2A 1XTOA 4F6HA 2GFJA 1Y44A 4UA4A 3PG4A 4KEQA 3FAIA 3KL7A 4Z60A 5ACRA 5ACPA 3VPEA 2YNVA 5FQAA 2YZ3A 2Y87A 3SRXA 3R2UA 2QDTA 2XF4A 1KR3A 2FU8A 4ZEJA 4TYFA 4Z5ZA 3QH8A 3AF6A 3WXCA 4EFZA 5K4NA 5A87A 4C1EA 3SFPA 3L6NA 4NQ4A 3PY6A 3ZNBA 4BZ3A 2BTNA 2UYXA 4EXSA 3X2XA 4HL1A 4NQ2A 5A5ZA 4O98A 5LMCA 2HB9A 1DDKA 2FHXA 1XM8A 5AXRA 2M5CA 3KNSA 5AHOA 3S0ZA 4GYUA 3IE2A 5B15A 3TP9A 3RKJA 5FQCA 4C09A 2P4ZA 5K4KA 1M2XA 2BG2A 2NZEA 3SW3A 2WYLA 2FU6A 2DKFA 2GFKA 4C1CA 4TZEA 3ADRA 1JJEA 1X8IA 2ZNBA 3SBLA 4V0HA 3IEMA 3IOGA 2YNWA 2NYPA 4LE6A 4D02A 4KEPA 2NXAA 1K07A 4EYLA 4JO0A 2BFKA 4HKYA 2WYMA 2OHJA 4RL0A 4FR7A 2P97A 4AD9A 5LCHA 3I13A 5DPXA 2FHXB 5AYAA 2QJSA 2OHHA 4J5HA 5EV6A 4D1UA 5EV8A 5FQBA 2BMIA 3DHAA 4EYBA 5HH5A 2ZO4A 5A0TA 2BG8B 4U4LA 3RPCA 2WRSA 2BGAA 2BIBA 4H0DA 3T3OA 1QH3A 4FSBA 1KO2A 3FCZA 3KNRA 3SD9A 2BFZA 4RBSA 3X30A 5ACTA 4YSLA 4UWOB 3DHBA 2ZWRA 5ACXA 2QDSA 4EYFA 5K0WA 1VJNA 4YSKA 2GCUA 4EXYA 5EH9A 5LSCA 2NZFA 1DD6A 3I14A 5HIQA 3SPUA 4UAMA 2VW8A 1MQOA 4Z7RA 2YNTA 5EHTA 1BC2A 1WRAA 2DOOA 3JXPA 2BFZB 4RAMA 3IDZA 2YNVB 4XWTA 2R2DA 1ZTCA 2BFLA 4AWYB 3AF5A 4AWZA 2OHIA 3P2UA 2WHGA 5K4MA 4RL2A 1BMCA 4RAWA 5AXOA 2YCBA 5HISA 2I7VA 4EY2A 5B1UA 2BC2A 4D1WA 3Q6VA 2ZZIA 1YCFA 4TZFA 1WW1A 3MD7A 2P1EA 4FEKA 5LM6A 2WYMC 2BG6A 2XR1A 2YNTB 5AHRA 5B3RA 3IELA 1KO3A 3I0VA 4C1HA 5ACSA 2YNUA 4NQ5A 4C1GA 4DILA 2AIOA 1E5DA 3LVZA 4XUKA 2A7MA 1ZKPA 2GMNA 4B87A 4RM5A 3X2YA 1VMEA 2BR6A 4ZNBA 4XWWA 3BC2A 3DH8A 3X2ZA 4UWSB 3BV6A 5ACWA 2Q9UA 2FM6A 3ZWFA 4Z67A 4F6ZA 1YCHA 3G1PA 5A0VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4D1T A;  4DIK A;  1L9Y A;  2GKL A;  3A4Y A;  1A8T A;  1HLK A;  3T3N A;  4ZO3 A;  1QH5 A;  2FU9 A;  4GYQ A;  3ZR9 A;  3VQZ A;  2Q0I A;  5EVB A;  4TYT A;  4Z5Y A;  3I15 A;  5EVK A;  2I7T A;  1SML A;  2P18 A;  3IEK A;  3H3E A;  1P9E A;  4TZB A;  5HH4 A;  3IE0 A;  2I7X A;  4NQ6 A;  3ESH A;  5KIL A;  4PVT A;  4AX1 B;  2CBN A;  3F9O A;  2M5D A;  3IE1 A;  3PY5 A;  3I11 A;  4Z6X A;  1BVT A;  1DXK A;  5LCA A;  3BK2 A;  3ZQ4 A;  2QED A;  4UWP B;  3BK1 A;  1A7T A;  4UWR B;  5ACU A;  2E7Y A;  2BG8 A;  1JJT A;  4GCW A;  5LLD A;  4YSB A;  5HIO A;  2FU7 A;  5IQK A;  2AZ4 A;  2Q0J A;  4D1V A;  3IOF A;  4BP0 A;  5ACV A;  5AEB A;  5HIP A;  5LCF A;  4AX0 B;  2Q42 A;  5HH6 A;  3AJ3 A;  5LS3 A;  1X8H A;  5EWA A;  1YCG A;  4HL2 A;  1VGN A;  2QIN A;  1WUO A;  1JT1 A;  5KIK A;  4CHL A;  2BG7 A;  4UBQ A;  4P62 A;  2H6A A;  2FK6 A;  3DHC A;  5EVD A;  4J5F A;  5ACQ A;  4PVO A;  5LE1 A;  1ZNB A;  2Y8A A;  3T9M A;  2Y8B A;  4C1D A;  1WUP A;  4WD6 A;  1X8G A;  5EW0 A;  4C1F A;  4TZ9 A;  3RKK A;  4ZO2 A;  1XTO A;  4F6H A;  2GFJ A;  1Y44 A;  4UA4 A;  3PG4 A;  4KEQ A;  3FAI A;  3KL7 A;  4Z60 A;  5ACR A;  5ACP A;  3VPE A;  2YNV A;  5FQA A;  2YZ3 A;  2Y87 A;  3SRX A;  3R2U A;  2QDT A;  2XF4 A;  1KR3 A;  2FU8 A;  4ZEJ A;  4TYF A;  4Z5Z A;  3QH8 A;  3AF6 A;  3WXC A;  4EFZ A;  5K4N A;  5A87 A;  4C1E A;  3SFP A;  3L6N A;  4NQ4 A;  3PY6 A;  3ZNB A;  4BZ3 A;  2BTN A;  2UYX A;  4EXS A;  3X2X A;  4HL1 A;  4NQ2 A;  5A5Z A;  4O98 A;  5LMC A;  2HB9 A;  1DDK A;  2FHX A;  1XM8 A;  5AXR A;  2M5C A;  3KNS A;  5AHO A;  3S0Z A;  4GYU A;  3IE2 A;  5B15 A;  3TP9 A;  3RKJ A;  5FQC A;  4C09 A;  2P4Z A;  5K4K A;  1M2X A;  2BG2 A;  2NZE A;  3SW3 A;  2WYL A;  2FU6 A;  2DKF A;  2GFK A;  4C1C A;  4TZE A;  3ADR A;  1JJE A;  1X8I A;  2ZNB A;  3SBL A;  4V0H A;  3IEM A;  3IOG A;  2YNW A;  2NYP A;  4LE6 A;  4D02 A;  4KEP A;  2NXA A;  1K07 A;  4EYL A;  4JO0 A;  2BFK A;  4HKY A;  2WYM A;  2OHJ A;  4RL0 A;  4FR7 A;  2P97 A;  4AD9 A;  5LCH A;  3I13 A;  5DPX A;  2FHX B;  5AYA A;  2QJS A;  2OHH A;  4J5H A;  5EV6 A;  4D1U A;  5EV8 A;  5FQB A;  2BMI A;  3DHA A;  4EYB A;  5HH5 A;  2ZO4 A;  5A0T A;  2BG8 B;  4U4L A;  3RPC A;  2WRS A;  2BGA A;  2BIB A;  4H0D A;  3T3O A;  1QH3 A;  4FSB A;  1KO2 A;  3FCZ A;  3KNR A;  3SD9 A;  2BFZ A;  4RBS A;  3X30 A;  5ACT A;  4YSL A;  4UWO B;  3DHB A;  2ZWR A;  5ACX A;  2QDS A;  4EYF A;  5K0W A;  1VJN A;  4YSK A;  2GCU A;  4EXY A;  5EH9 A;  5LSC A;  2NZF A;  1DD6 A;  3I14 A;  5HIQ A;  3SPU A;  4UAM A;  2VW8 A;  1MQO A;  4Z7R A;  2YNT A;  5EHT A;  1BC2 A;  1WRA A;  2DOO A;  3JXP A;  2BFZ B;  4RAM A;  3IDZ A;  2YNV B;  4XWT A;  2R2D A;  1ZTC A;  2BFL A;  4AWY B;  3AF5 A;  4AWZ A;  2OHI A;  3P2U A;  2WHG A;  5K4M A;  4RL2 A;  1BMC A;  4RAW A;  5AXO A;  2YCB A;  5HIS A;  2I7V A;  4EY2 A;  5B1U A;  2BC2 A;  4D1W A;  3Q6V A;  2ZZI A;  1YCF A;  4TZF A;  1WW1 A;  3MD7 A;  2P1E A;  4FEK A;  5LM6 A;  2WYM C;  2BG6 A;  2XR1 A;  2YNT B;  5AHR A;  5B3R A;  3IEL A;  1KO3 A;  3I0V A;  4C1H A;  5ACS A;  2YNU A;  4NQ5 A;  4C1G A;  4DIL A;  2AIO A;  1E5D A;  3LVZ A;  4XUK A;  2A7M A;  1ZKP A;  2GMN A;  4B87 A;  4RM5 A;  3X2Y A;  1VME A;  2BR6 A;  4ZNB A;  4XWW A;  3BC2 A;  3DH8 A;  3X2Z A;  4UWS B;  3BV6 A;  5ACW A;  2Q9U A;  2FM6 A;  3ZWF A;  4Z67 A;  4F6Z A;  1YCH A;  3G1P A;  5A0V A; 
#chains in the Genus database with same CATH topology
 4D1T A;  4DIK A;  1L9Y A;  2GKL A;  3A4Y A;  1A8T A;  1HLK A;  3T3N A;  4ZO3 A;  1QH5 A;  2FU9 A;  4GYQ A;  3ZR9 A;  3VQZ A;  2Q0I A;  5EVB A;  4TYT A;  4Z5Y A;  3I15 A;  5EVK A;  2I7T A;  1SML A;  2P18 A;  3IEK A;  3H3E A;  1P9E A;  4TZB A;  5HH4 A;  3IE0 A;  2I7X A;  4NUR A;  4NQ6 A;  3ESH A;  5KIL A;  4PVT A;  4AX1 B;  2CG3 A;  2CBN A;  3F9O A;  2M5D A;  3IE1 A;  3PY5 A;  3I11 A;  4Z6X A;  1BVT A;  1DXK A;  5LCA A;  3BK2 A;  3ZQ4 A;  2QED A;  4UWP B;  3BK1 A;  1A7T A;  4UWR B;  5AIJ A;  5ACU A;  2E7Y A;  2BG8 A;  1JJT A;  4GCW A;  5LLD A;  4YSB A;  5HIO A;  2FU7 A;  5IQK A;  2AZ4 A;  2Q0J A;  4D1V A;  2CFU A;  3IOF A;  4BP0 A;  5ACV A;  5AEB A;  5HIP A;  5LCF A;  4AX0 B;  2Q42 A;  5HH6 A;  3AJ3 A;  5LS3 A;  1X8H A;  5EWA A;  1YCG A;  4HL2 A;  1VGN A;  2QIN A;  1WUO A;  1JT1 A;  5KIK A;  4CHL A;  2BG7 A;  4UBQ A;  4P62 A;  2H6A A;  2FK6 A;  3DHC A;  5EVD A;  4J5F A;  5ACQ A;  4PVO A;  5LE1 A;  1ZNB A;  2Y8A A;  3T9M A;  2Y8B A;  4C1D A;  1WUP A;  4WD6 A;  1X8G A;  5EW0 A;  4C1F A;  4TZ9 A;  3RKK A;  4ZO2 A;  1XTO A;  4F6H A;  2GFJ A;  1Y44 A;  4UA4 A;  3PG4 A;  4KEQ A;  3FAI A;  3KL7 A;  4Z60 A;  5ACR A;  5ACP A;  3VPE A;  2YNV A;  5FQA A;  4AXH A;  2YZ3 A;  2Y87 A;  3SRX A;  3R2U A;  2QDT A;  2XF4 A;  1KR3 A;  2FU8 A;  4ZEJ A;  4TYF A;  4Z5Z A;  3QH8 A;  3AF6 A;  3WXC A;  4EFZ A;  5K4N A;  5A87 A;  4C1E A;  3SFP A;  3L6N A;  4NQ4 A;  3PY6 A;  3ZNB A;  4BZ3 A;  2BTN A;  2UYX A;  4EXS A;  3X2X A;  4HL1 A;  4NQ2 A;  5A5Z A;  4O98 A;  5LMC A;  2HB9 A;  1DDK A;  2FHX A;  1XM8 A;  5AXR A;  2M5C A;  3KNS A;  5AHO A;  3S0Z A;  4GYU A;  3IE2 A;  5B15 A;  3TP9 A;  3RKJ A;  5FQC A;  4C09 A;  2P4Z A;  5K4K A;  1M2X A;  2BG2 A;  2NZE A;  3SW3 A;  2WYL A;  2FU6 A;  2DKF A;  2GFK A;  4C1C A;  4TZE A;  3ADR A;  1JJE A;  1X8I A;  2ZNB A;  3SBL A;  4V0H A;  3IEM A;  3IOG A;  2YNW A;  2NYP A;  4LE6 A;  4KEP A;  4D02 A;  2NXA A;  1K07 A;  4EYL A;  4JO0 A;  2BFK A;  4HKY A;  2WYM A;  2OHJ A;  4RL0 A;  5AJL A;  4FR7 A;  2P97 A;  4AD9 A;  5LCH A;  3I13 A;  5DPX A;  2FHX B;  5AYA A;  2QJS A;  2OHH A;  4J5H A;  5EV6 A;  4D1U A;  5EV8 A;  5FQB A;  2BMI A;  2CG2 A;  3DHA A;  4EYB A;  2YHE A;  5HH5 A;  2ZO4 A;  5A0T A;  2BG8 B;  4U4L A;  3RPC A;  2WRS A;  2BGA A;  2BIB A;  4H0D A;  3T3O A;  1QH3 A;  2CFZ A;  4FSB A;  1KO2 A;  3FCZ A;  3KNR A;  3SD9 A;  2BFZ A;  4RBS A;  3X30 A;  5ACT A;  4YSL A;  4UWO B;  3DHB A;  2ZWR A;  5ACX A;  2QDS A;  4PDX A;  4EYF A;  5K0W A;  1VJN A;  4YSK A;  2GCU A;  4EXY A;  5EH9 A;  5LSC A;  2NZF A;  4AV7 A;  1DD6 A;  3I14 A;  5HIQ A;  3SPU A;  4UAM A;  2VW8 A;  1MQO A;  4Z7R A;  2YNT A;  5EHT A;  1BC2 A;  1WRA A;  2DOO A;  3JXP A;  2BFZ B;  4RAM A;  3IDZ A;  2YNV B;  4XWT A;  2R2D A;  1ZTC A;  2BFL A;  4AWY B;  3AF5 A;  4AWZ A;  2OHI A;  3P2U A;  2WHG A;  5K4M A;  4RL2 A;  1BMC A;  4RAW A;  5AXO A;  2YCB A;  5HIS A;  2I7V A;  4EY2 A;  5B1U A;  2BC2 A;  4D1W A;  3Q6V A;  2ZZI A;  1YCF A;  4TZF A;  1WW1 A;  3MD7 A;  2P1E A;  4FEK A;  5LM6 A;  5A23 A;  2WYM C;  2BG6 A;  2XR1 A;  2YNT B;  5AHR A;  5B3R A;  3IEL A;  1KO3 A;  3I0V A;  4C1H A;  5ACS A;  2YNU A;  4NQ5 A;  4C1G A;  4DIL A;  2AIO A;  1E5D A;  3LVZ A;  4XUK A;  2A7M A;  1ZKP A;  2GMN A;  4B87 A;  4RM5 A;  3X2Y A;  1VME A;  2BR6 A;  4ZNB A;  4XWW A;  3BC2 A;  3DH8 A;  3X2Z A;  4UWS B;  3BV6 A;  5ACW A;  2Q9U A;  2FM6 A;  3ZWF A;  4Z67 A;  4F6Z A;  1YCH A;  3G1P A;  5A0V A; 
#chains in the Genus database with same CATH homology
 4D1T A;  4DIK A;  1L9Y A;  2GKL A;  3A4Y A;  1A8T A;  1HLK A;  3T3N A;  4ZO3 A;  1QH5 A;  2FU9 A;  4GYQ A;  3ZR9 A;  3VQZ A;  2Q0I A;  5EVB A;  4TYT A;  4Z5Y A;  3I15 A;  5EVK A;  2I7T A;  1SML A;  2P18 A;  3IEK A;  3H3E A;  1P9E A;  4TZB A;  5HH4 A;  3IE0 A;  2I7X A;  4NQ6 A;  3ESH A;  5KIL A;  4PVT A;  4AX1 B;  2CBN A;  3F9O A;  2M5D A;  3IE1 A;  3PY5 A;  3I11 A;  4Z6X A;  1BVT A;  1DXK A;  5LCA A;  3BK2 A;  3ZQ4 A;  2QED A;  4UWP B;  3BK1 A;  1A7T A;  4UWR B;  5ACU A;  2E7Y A;  2BG8 A;  1JJT A;  4GCW A;  5LLD A;  4YSB A;  5HIO A;  2FU7 A;  5IQK A;  2AZ4 A;  2Q0J A;  4D1V A;  3IOF A;  4BP0 A;  5ACV A;  5AEB A;  5HIP A;  5LCF A;  4AX0 B;  2Q42 A;  5HH6 A;  3AJ3 A;  5LS3 A;  1X8H A;  5EWA A;  1YCG A;  4HL2 A;  1VGN A;  2QIN A;  1WUO A;  1JT1 A;  5KIK A;  4CHL A;  2BG7 A;  4UBQ A;  4P62 A;  2H6A A;  2FK6 A;  3DHC A;  5EVD A;  4J5F A;  5ACQ A;  4PVO A;  5LE1 A;  1ZNB A;  2Y8A A;  3T9M A;  2Y8B A;  4C1D A;  1WUP A;  4WD6 A;  1X8G A;  5EW0 A;  4C1F A;  4TZ9 A;  3RKK A;  4ZO2 A;  1XTO A;  4F6H A;  2GFJ A;  1Y44 A;  4UA4 A;  3PG4 A;  4KEQ A;  3FAI A;  3KL7 A;  4Z60 A;  5ACR A;  5ACP A;  3VPE A;  2YNV A;  5FQA A;  2YZ3 A;  2Y87 A;  3SRX A;  3R2U A;  2QDT A;  2XF4 A;  1KR3 A;  2FU8 A;  4ZEJ A;  4TYF A;  4Z5Z A;  3QH8 A;  3AF6 A;  3WXC A;  4EFZ A;  5K4N A;  5A87 A;  4C1E A;  3SFP A;  3L6N A;  4NQ4 A;  3PY6 A;  3ZNB A;  4BZ3 A;  2BTN A;  2UYX A;  4EXS A;  3X2X A;  4HL1 A;  4NQ2 A;  5A5Z A;  4O98 A;  5LMC A;  2HB9 A;  1DDK A;  2FHX A;  1XM8 A;  5AXR A;  2M5C A;  3KNS A;  5AHO A;  3S0Z A;  4GYU A;  3IE2 A;  5B15 A;  3TP9 A;  3RKJ A;  5FQC A;  4C09 A;  2P4Z A;  5K4K A;  1M2X A;  2BG2 A;  2NZE A;  3SW3 A;  2WYL A;  2FU6 A;  2DKF A;  2GFK A;  4C1C A;  4TZE A;  3ADR A;  1JJE A;  1X8I A;  2ZNB A;  3SBL A;  4V0H A;  3IEM A;  3IOG A;  2YNW A;  2NYP A;  4LE6 A;  4D02 A;  4KEP A;  2NXA A;  1K07 A;  4EYL A;  4JO0 A;  2BFK A;  4HKY A;  2WYM A;  2OHJ A;  4RL0 A;  4FR7 A;  2P97 A;  4AD9 A;  5LCH A;  3I13 A;  5DPX A;  2FHX B;  5AYA A;  2QJS A;  2OHH A;  4J5H A;  5EV6 A;  4D1U A;  5EV8 A;  5FQB A;  2BMI A;  3DHA A;  4EYB A;  5HH5 A;  2ZO4 A;  5A0T A;  2BG8 B;  4U4L A;  3RPC A;  2WRS A;  2BGA A;  2BIB A;  4H0D A;  3T3O A;  1QH3 A;  4FSB A;  1KO2 A;  3FCZ A;  3KNR A;  3SD9 A;  2BFZ A;  4RBS A;  3X30 A;  5ACT A;  4YSL A;  4UWO B;  3DHB A;  2ZWR A;  5ACX A;  2QDS A;  4EYF A;  5K0W A;  1VJN A;  4YSK A;  2GCU A;  4EXY A;  5EH9 A;  5LSC A;  2NZF A;  1DD6 A;  3I14 A;  5HIQ A;  3SPU A;  4UAM A;  2VW8 A;  1MQO A;  4Z7R A;  2YNT A;  5EHT A;  1BC2 A;  1WRA A;  2DOO A;  3JXP A;  2BFZ B;  4RAM A;  3IDZ A;  2YNV B;  4XWT A;  2R2D A;  1ZTC A;  2BFL A;  4AWY B;  3AF5 A;  4AWZ A;  2OHI A;  3P2U A;  2WHG A;  5K4M A;  4RL2 A;  1BMC A;  4RAW A;  5AXO A;  2YCB A;  5HIS A;  2I7V A;  4EY2 A;  5B1U A;  2BC2 A;  4D1W A;  3Q6V A;  2ZZI A;  1YCF A;  4TZF A;  1WW1 A;  3MD7 A;  2P1E A;  4FEK A;  5LM6 A;  2WYM C;  2BG6 A;  2XR1 A;  2YNT B;  5AHR A;  5B3R A;  3IEL A;  1KO3 A;  3I0V A;  4C1H A;  5ACS A;  2YNU A;  4NQ5 A;  4C1G A;  4DIL A;  2AIO A;  1E5D A;  3LVZ A;  4XUK A;  2A7M A;  1ZKP A;  2GMN A;  4B87 A;  4RM5 A;  3X2Y A;  1VME A;  2BR6 A;  4ZNB A;  4XWW A;  3BC2 A;  3DH8 A;  3X2Z A;  4UWS B;  3BV6 A;  5ACW A;  2Q9U A;  2FM6 A;  3ZWF A;  4Z67 A;  4F6Z A;  1YCH A;  3G1P A;  5A0V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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