5LS3A

Crystal structure of metallo-beta-lactamase spm-1 with y58c mutation
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
245
structure length
239
Chain Sequence
DHVDLPYNLTATKIDSDVFVVTDRDFCSSNVLVAKMLDGTVVIVSSPFENLGTQTLMDWVAKTMKPKKVVAINTHFHLDGTGGNEIYKKMGAETWSSDLTKQLRLEENKKDFYKNEDLKRRILSSHPVPADNVFDLKQGKVFSFSNELVEVSFPGPAHSPDNVVVYFPKKKLLFGGCMIKPKELGYLGDANVKAWPDSARRLKKFDAKIVIPGHGEWGGPEMVNKTIKVAEKAVGEMRL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title (19) F-NMR Reveals the Role of Mobile Loops in Product and Inhibitor Binding by the Sao Paulo Metallo-beta-Lactamase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Pseudomonas aeruginosa
molecule keywords Beta-lactamase IMP-1
total genus 80
structure length 239
sequence length 245
chains with identical sequence B
ec nomenclature ec 3.5.2.6: Beta-lactamase.
pdb deposition date 2016-08-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5ls3A00
4EY2A 2WYLA 3VPEA 2Y8BA 5EH9A 1YCHA 1ZKPA 1Y44A 4XWTA 3A4YA 1A7TA 1DDKA 1K07A 5A0VA 1KO3A 3T3OA 4J5FA 1KO2A 4F6HA 4C1FA 4JO0A 2I7VA 5LCHA 5EWAA 2VW8A 3IELA 3SBLA 2Y87A 5ACTA 3DHBA 2FHXA 3KNRA 1X8IA 2Q0IA 1DXKA 4AWYB 1WUPA 5IQKA 4O98A 3BK1A 4D1TA 2BR6A 4D1VA 5ACSA 4KEPA 2ZNBA 1YCGA 3PY6A 1HLKA 3BV6A 2CBNA 5B15A 4C09A 5HIQA 3T3NA 4RL2A 4D02A 4EYBA 2YNTA 4UA4A 4EFZA 3H3EA 2WYMA 3SD9A 5AXRA 4ZO3A 4Z6XA 1L9YA 3SFPA 5LS3A 2BG8B 5KILA 3SRXA 5AHOA 3IEMA 2P1EA 3ESHA 5FQAA 2QDSA 3AJ3A 4EYFA 3FCZA 4GYUA 4WD6A 3BC2A 4BZ3A 1WUOA 2QDTA 5EVBA 5AEBA 4H0DA 1VJNA 3X2YA 4TYTA 3I0VA 3P2UA 4D1UA 3VQZA 2P4ZA 2XR1A 2ZWRA 4TZEA 3S0ZA 5FQBA 1E5DA 4NQ5A 1BVTA 2Q0JA 1KR3A 2I7XA 4C1CA 3T9MA 5ACXA 4V0HA 2FU6A 4NQ4A 3IEKA 3L6NA 2P18A 4C1HA 5HH6A 5EV6A 3ZR9A 5K0WA 3DHCA 4DILA 3I11A 2BG6A 3I15A 5EHTA 4Z60A 2BMIA 2AZ4A 2FU8A 5AXOA 5KIKA 4ZO2A 4TYFA 5LM6A 2GFKA 2FM6A 4RM5A 2NZEA 1BMCA 5LMCA 4C1DA 2XF4A 2QJSA 4BP0A 4TZ9A 2UYXA 2GKLA 2P97A 4YSLA 4C1GA 4UAMA 4FR7A 3IDZA 2AIOA 2BG2A 2OHIA 2GCUA 3JXPA 3IE2A 4XUKA 4AD9A 2H6AA 5HIOA 2FK6A 2WYMC 4FSBA 2ZZIA 5HH5A 2WHGA 3X2ZA 3AF5A 3X2XA 2BG8A 2QEDA 3DHAA 2BGAA 5DPXA 4Z5YA 2ZO4A 1MQOA 4Z67A 5AYAA 2OHHA 3Q6VA 4HL2A 2YNVB 3RKKA 5HISA 5K4NA 1XTOA 4DIKA 5ACUA 2BFZB 2BTNA 1QH5A 4YSBA 4AX0B 5A87A 5LSCA 3KNSA 3FAIA 1YCFA 3I14A 4RBSA 2FU9A 4LE6A 5EVKA 5HIPA 3R2UA 3RKJA 5A0TA 5ACVA 2BFLA 1JJTA 3IE0A 4AX1B 3WXCA 1WW1A 4UWPB 5K4MA 1VGNA 2A7MA 2DKFA 3F9OA 2BG7A 4PVOA 3ZQ4A 4GCWA 4EYLA 2YNUA 3IOFA 4TZFA 3SPUA 1ZTCA 1A8TA 2Q42A 1JJEA 4PVTA 2GMNA 3I13A 5LCFA 1XM8A 5ACRA 3KL7A 2I7TA 3G1PA 2R2DA 4Z7RA 2QINA 4GYQA 2GFJA 3MD7A 1BC2A 5B1UA 2M5DA 2YNVA 4RL0A 4UWRB 3RPCA 1X8GA 2FU7A 3SW3A 4D1WA 4UBQA 1M2XA 5EV8A 4HKYA 2BFZA 4RAWA 4P62A 4UWSB 5K4KA 4B87A 5LE1A 2NZFA 1QH3A 2WRSA 3LVZA 5EVDA 1X8HA 2FHXB 1WRAA 3DH8A 4J5HA 5HH4A 2YZ3A 4ZEJA 4EXSA 3BK2A 3X30A 4NQ6A 4HL1A 4FEKA 2YNTB 2E7YA 4UWOB 4U4LA 2Y8AA 4AWZA 4F6ZA 5EW0A 5ACPA 3QH8A 4CHLA 4EXYA 1SMLA 5AHRA 4C1EA 2BIBA 4NQ2A 5FQCA 3TP9A 2YCBA 2M5CA 5LCAA 4ZNBA 2YNWA 4YSKA 4TZBA 5LLDA 3ZNBA 2DOOA 3IOGA 3AF6A 5A5ZA 1P9EA 4Z5ZA 2NYPA 2HB9A 4KEQA 2BC2A 3ADRA 2BFKA 4RAMA 5B3RA 1DD6A 1ZNBA 3ZWFA 2OHJA 3PY5A 2NXAA 5ACQA 3PG4A 5ACWA 1VMEA 3IE1A 4XWWA 1JT1A 2Q9UA
chains in the Genus database with same CATH superfamily
4EY2A 2WYLA 3VPEA 2Y8BA 5EH9A 1YCHA 1ZKPA 1Y44A 4XWTA 3A4YA 1A7TA 1DDKA 1K07A 2CG3A 5A0VA 1KO3A 3T3OA 4J5FA 1KO2A 4F6HA 4C1FA 4JO0A 2I7VA 5LCHA 5EWAA 2VW8A 3IELA 3SBLA 2Y87A 5ACTA 3DHBA 2FHXA 3KNRA 1X8IA 2Q0IA 1DXKA 4AWYB 1WUPA 5IQKA 4O98A 3BK1A 4D1TA 2BR6A 4D1VA 5ACSA 4KEPA 2ZNBA 1YCGA 3PY6A 1HLKA 3BV6A 2CBNA 5B15A 4C09A 5HIQA 3T3NA 4RL2A 4D02A 4EYBA 2YNTA 4UA4A 4EFZA 3H3EA 2WYMA 5AJLA 3SD9A 5AXRA 4ZO3A 4Z6XA 1L9YA 3SFPA 5LS3A 2BG8B 5KILA 3SRXA 5AHOA 3IEMA 2P1EA 3ESHA 5FQAA 2CFUA 2QDSA 3AJ3A 4EYFA 3FCZA 4GYUA 4WD6A 3BC2A 4BZ3A 1WUOA 2QDTA 5EVBA 5AEBA 4H0DA 1VJNA 5A23A 3X2YA 4TYTA 3I0VA 3P2UA 4D1UA 3VQZA 2P4ZA 2XR1A 2ZWRA 4TZEA 3S0ZA 5FQBA 1E5DA 4NQ5A 1BVTA 2Q0JA 1KR3A 2I7XA 4C1CA 3T9MA 5ACXA 4V0HA 2FU6A 4NQ4A 3IEKA 3L6NA 2P18A 4C1HA 5HH6A 5EV6A 3ZR9A 5K0WA 3DHCA 4DILA 3I11A 2BG6A 3I15A 5AIJA 5EHTA 4Z60A 2BMIA 2AZ4A 2FU8A 5AXOA 5KIKA 4ZO2A 4TYFA 5LM6A 2GFKA 2FM6A 4RM5A 2NZEA 4AXHA 1BMCA 5LMCA 4C1DA 2XF4A 2QJSA 4BP0A 4TZ9A 2UYXA 2GKLA 2P97A 4YSLA 4C1GA 4UAMA 4FR7A 3IDZA 2AIOA 2BG2A 2OHIA 2GCUA 3JXPA 3IE2A 4XUKA 4AD9A 2H6AA 5HIOA 2FK6A 2WYMC 4FSBA 2ZZIA 5HH5A 2WHGA 3X2ZA 3AF5A 3X2XA 2BG8A 2QEDA 3DHAA 2BGAA 5DPXA 4Z5YA 2ZO4A 1MQOA 4Z67A 5AYAA 2OHHA 3Q6VA 4HL2A 2YNVB 3RKKA 5HISA 5K4NA 1XTOA 4DIKA 5ACUA 2BFZB 2BTNA 1QH5A 2CFZA 4YSBA 4AX0B 5A87A 5LSCA 3KNSA 3FAIA 1YCFA 3I14A 4RBSA 2FU9A 4LE6A 5EVKA 5HIPA 3R2UA 3RKJA 5A0TA 5ACVA 2BFLA 1JJTA 3IE0A 4AX1B 3WXCA 1WW1A 4UWPB 5K4MA 1VGNA 2A7MA 2DKFA 3F9OA 2BG7A 4PVOA 3ZQ4A 4GCWA 4EYLA 2YNUA 3IOFA 4TZFA 3SPUA 1ZTCA 1A8TA 4AV7A 2Q42A 1JJEA 4PVTA 2GMNA 3I13A 5LCFA 1XM8A 5ACRA 3KL7A 2I7TA 3G1PA 2R2DA 4Z7RA 2QINA 4GYQA 2CG2A 2GFJA 3MD7A 1BC2A 5B1UA 2M5DA 2YNVA 4RL0A 4UWRB 3RPCA 1X8GA 2FU7A 3SW3A 4D1WA 4UBQA 1M2XA 5EV8A 2YHEA 4HKYA 2BFZA 4RAWA 4P62A 4UWSB 5K4KA 4B87A 5LE1A 2NZFA 1QH3A 2WRSA 3LVZA 5EVDA 1X8HA 2FHXB 1WRAA 4NURA 3DH8A 4J5HA 5HH4A 2YZ3A 4ZEJA 4EXSA 3BK2A 3X30A 4NQ6A 4HL1A 4FEKA 2YNTB 2E7YA 4UWOB 4U4LA 2Y8AA 4AWZA 4F6ZA 5EW0A 5ACPA 3QH8A 4CHLA 4EXYA 1SMLA 5AHRA 4C1EA 2BIBA 4NQ2A 5FQCA 3TP9A 2YCBA 2M5CA 5LCAA 4ZNBA 2YNWA 4YSKA 4TZBA 5LLDA 3ZNBA 2DOOA 4PDXA 3IOGA 3AF6A 5A5ZA 1P9EA 4Z5ZA 2NYPA 2HB9A 4KEQA 2BC2A 3ADRA 2BFKA 4RAMA 5B3RA 1DD6A 1ZNBA 3ZWFA 2OHJA 3PY5A 2NXAA 5ACQA 3PG4A 5ACWA 1VMEA 3IE1A 4XWWA 1JT1A 2Q9UA
chains in the Genus database with same CATH topology
4EY2A 2WYLA 3VPEA 2Y8BA 5EH9A 1YCHA 1ZKPA 1Y44A 4XWTA 3A4YA 1A7TA 1DDKA 1K07A 5A0VA 1KO3A 3T3OA 4J5FA 1KO2A 4F6HA 4C1FA 4JO0A 2I7VA 5LCHA 5EWAA 2VW8A 3IELA 3SBLA 2Y87A 5ACTA 3DHBA 2FHXA 3KNRA 1X8IA 2Q0IA 1DXKA 4AWYB 1WUPA 5IQKA 4O98A 3BK1A 4D1TA 2BR6A 4D1VA 5ACSA 4KEPA 2ZNBA 1YCGA 3PY6A 1HLKA 3BV6A 2CBNA 5B15A 4C09A 5HIQA 3T3NA 4RL2A 4D02A 4EYBA 2YNTA 4UA4A 4EFZA 3H3EA 2WYMA 3SD9A 5AXRA 4ZO3A 4Z6XA 1L9YA 3SFPA 5LS3A 2BG8B 5KILA 3SRXA 5AHOA 3IEMA 2P1EA 3ESHA 5FQAA 2QDSA 3AJ3A 4EYFA 3FCZA 4GYUA 4WD6A 3BC2A 4BZ3A 1WUOA 2QDTA 5EVBA 5AEBA 4H0DA 1VJNA 3X2YA 4TYTA 3I0VA 3P2UA 4D1UA 3VQZA 2P4ZA 2XR1A 2ZWRA 4TZEA 3S0ZA 5FQBA 1E5DA 4NQ5A 1BVTA 2Q0JA 1KR3A 2I7XA 4C1CA 3T9MA 5ACXA 4V0HA 2FU6A 4NQ4A 3IEKA 3L6NA 2P18A 4C1HA 5HH6A 5EV6A 3ZR9A 5K0WA 3DHCA 4DILA 3I11A 2BG6A 3I15A 5EHTA 4Z60A 2BMIA 2AZ4A 2FU8A 5AXOA 5KIKA 4ZO2A 4TYFA 5LM6A 2GFKA 2FM6A 4RM5A 2NZEA 1BMCA 5LMCA 4C1DA 2XF4A 2QJSA 4BP0A 4TZ9A 2UYXA 2GKLA 2P97A 4YSLA 4C1GA 4UAMA 4FR7A 3IDZA 2AIOA 2BG2A 2OHIA 2GCUA 3JXPA 3IE2A 4XUKA 4AD9A 2H6AA 5HIOA 2FK6A 2WYMC 4FSBA 2ZZIA 5HH5A 2WHGA 3X2ZA 3AF5A 3X2XA 2BG8A 2QEDA 3DHAA 2BGAA 5DPXA 4Z5YA 2ZO4A 1MQOA 4Z67A 5AYAA 2OHHA 3Q6VA 4HL2A 2YNVB 3RKKA 5HISA 5K4NA 1XTOA 4DIKA 5ACUA 2BFZB 2BTNA 1QH5A 4YSBA 4AX0B 5A87A 5LSCA 3KNSA 3FAIA 1YCFA 3I14A 4RBSA 2FU9A 4LE6A 5EVKA 5HIPA 3R2UA 3RKJA 5A0TA 5ACVA 2BFLA 1JJTA 3IE0A 4AX1B 3WXCA 1WW1A 4UWPB 5K4MA 1VGNA 2A7MA 2DKFA 3F9OA 2BG7A 4PVOA 3ZQ4A 4GCWA 4EYLA 2YNUA 3IOFA 4TZFA 3SPUA 1ZTCA 1A8TA 2Q42A 1JJEA 4PVTA 2GMNA 3I13A 5LCFA 1XM8A 5ACRA 3KL7A 2I7TA 3G1PA 2R2DA 4Z7RA 2QINA 4GYQA 2GFJA 3MD7A 1BC2A 5B1UA 2M5DA 2YNVA 4RL0A 4UWRB 3RPCA 1X8GA 2FU7A 3SW3A 4D1WA 4UBQA 1M2XA 5EV8A 4HKYA 2BFZA 4RAWA 4P62A 4UWSB 5K4KA 4B87A 5LE1A 2NZFA 1QH3A 2WRSA 3LVZA 5EVDA 1X8HA 2FHXB 1WRAA 3DH8A 4J5HA 5HH4A 2YZ3A 4ZEJA 4EXSA 3BK2A 3X30A 4NQ6A 4HL1A 4FEKA 2YNTB 2E7YA 4UWOB 4U4LA 2Y8AA 4AWZA 4F6ZA 5EW0A 5ACPA 3QH8A 4CHLA 4EXYA 1SMLA 5AHRA 4C1EA 2BIBA 4NQ2A 5FQCA 3TP9A 2YCBA 2M5CA 5LCAA 4ZNBA 2YNWA 4YSKA 4TZBA 5LLDA 3ZNBA 2DOOA 3IOGA 3AF6A 5A5ZA 1P9EA 4Z5ZA 2NYPA 2HB9A 4KEQA 2BC2A 3ADRA 2BFKA 4RAMA 5B3RA 1DD6A 1ZNBA 3ZWFA 2OHJA 3PY5A 2NXAA 5ACQA 3PG4A 5ACWA 1VMEA 3IE1A 4XWWA 1JT1A 2Q9UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EY2 A;  2WYL A;  3VPE A;  2Y8B A;  5EH9 A;  1YCH A;  1ZKP A;  1Y44 A;  4XWT A;  3A4Y A;  1A7T A;  1DDK A;  1K07 A;  5A0V A;  1KO3 A;  3T3O A;  4J5F A;  1KO2 A;  4F6H A;  4C1F A;  4JO0 A;  2I7V A;  5LCH A;  5EWA A;  2VW8 A;  3IEL A;  3SBL A;  2Y87 A;  5ACT A;  3DHB A;  2FHX A;  3KNR A;  1X8I A;  2Q0I A;  1DXK A;  4AWY B;  1WUP A;  5IQK A;  4O98 A;  3BK1 A;  4D1T A;  2BR6 A;  4D1V A;  5ACS A;  4KEP A;  2ZNB A;  1YCG A;  3PY6 A;  1HLK A;  3BV6 A;  2CBN A;  5B15 A;  4C09 A;  5HIQ A;  3T3N A;  4RL2 A;  4D02 A;  4EYB A;  2YNT A;  4UA4 A;  4EFZ A;  3H3E A;  2WYM A;  3SD9 A;  5AXR A;  4ZO3 A;  4Z6X A;  1L9Y A;  3SFP A;  5LS3 A;  2BG8 B;  5KIL A;  3SRX A;  5AHO A;  3IEM A;  2P1E A;  3ESH A;  5FQA A;  2QDS A;  3AJ3 A;  4EYF A;  3FCZ A;  4GYU A;  4WD6 A;  3BC2 A;  4BZ3 A;  1WUO A;  2QDT A;  5EVB A;  5AEB A;  4H0D A;  1VJN A;  3X2Y A;  4TYT A;  3I0V A;  3P2U A;  4D1U A;  3VQZ A;  2P4Z A;  2XR1 A;  2ZWR A;  4TZE A;  3S0Z A;  5FQB A;  1E5D A;  4NQ5 A;  1BVT A;  2Q0J A;  1KR3 A;  2I7X A;  4C1C A;  3T9M A;  5ACX A;  4V0H A;  2FU6 A;  4NQ4 A;  3IEK A;  3L6N A;  2P18 A;  4C1H A;  5HH6 A;  5EV6 A;  3ZR9 A;  5K0W A;  3DHC A;  4DIL A;  3I11 A;  2BG6 A;  3I15 A;  5EHT A;  4Z60 A;  2BMI A;  2AZ4 A;  2FU8 A;  5AXO A;  5KIK A;  4ZO2 A;  4TYF A;  5LM6 A;  2GFK A;  2FM6 A;  4RM5 A;  2NZE A;  1BMC A;  5LMC A;  4C1D A;  2XF4 A;  2QJS A;  4BP0 A;  4TZ9 A;  2UYX A;  2GKL A;  2P97 A;  4YSL A;  4C1G A;  4UAM A;  4FR7 A;  3IDZ A;  2AIO A;  2BG2 A;  2OHI A;  2GCU A;  3JXP A;  3IE2 A;  4XUK A;  4AD9 A;  2H6A A;  5HIO A;  2FK6 A;  2WYM C;  4FSB A;  2ZZI A;  5HH5 A;  2WHG A;  3X2Z A;  3AF5 A;  3X2X A;  2BG8 A;  2QED A;  3DHA A;  2BGA A;  5DPX A;  4Z5Y A;  2ZO4 A;  1MQO A;  4Z67 A;  5AYA A;  2OHH A;  3Q6V A;  4HL2 A;  2YNV B;  3RKK A;  5HIS A;  5K4N A;  1XTO A;  4DIK A;  5ACU A;  2BFZ B;  2BTN A;  1QH5 A;  4YSB A;  4AX0 B;  5A87 A;  5LSC A;  3KNS A;  3FAI A;  1YCF A;  3I14 A;  4RBS A;  2FU9 A;  4LE6 A;  5EVK A;  5HIP A;  3R2U A;  3RKJ A;  5A0T A;  5ACV A;  2BFL A;  1JJT A;  3IE0 A;  4AX1 B;  3WXC A;  1WW1 A;  4UWP B;  5K4M A;  1VGN A;  2A7M A;  2DKF A;  3F9O A;  2BG7 A;  4PVO A;  3ZQ4 A;  4GCW A;  4EYL A;  2YNU A;  3IOF A;  4TZF A;  3SPU A;  1ZTC A;  1A8T A;  2Q42 A;  1JJE A;  4PVT A;  2GMN A;  3I13 A;  5LCF A;  1XM8 A;  5ACR A;  3KL7 A;  2I7T A;  3G1P A;  2R2D A;  4Z7R A;  2QIN A;  4GYQ A;  2GFJ A;  3MD7 A;  1BC2 A;  5B1U A;  2M5D A;  2YNV A;  4RL0 A;  4UWR B;  3RPC A;  1X8G A;  2FU7 A;  3SW3 A;  4D1W A;  4UBQ A;  1M2X A;  5EV8 A;  4HKY A;  2BFZ A;  4RAW A;  4P62 A;  4UWS B;  5K4K A;  4B87 A;  5LE1 A;  2NZF A;  1QH3 A;  2WRS A;  3LVZ A;  5EVD A;  1X8H A;  2FHX B;  1WRA A;  3DH8 A;  4J5H A;  5HH4 A;  2YZ3 A;  4ZEJ A;  4EXS A;  3BK2 A;  3X30 A;  4NQ6 A;  4HL1 A;  4FEK A;  2YNT B;  2E7Y A;  4UWO B;  4U4L A;  2Y8A A;  4AWZ A;  4F6Z A;  5EW0 A;  5ACP A;  3QH8 A;  4CHL A;  4EXY A;  1SML A;  5AHR A;  4C1E A;  2BIB A;  4NQ2 A;  5FQC A;  3TP9 A;  2YCB A;  2M5C A;  5LCA A;  4ZNB A;  2YNW A;  4YSK A;  4TZB A;  5LLD A;  3ZNB A;  2DOO A;  3IOG A;  3AF6 A;  5A5Z A;  1P9E A;  4Z5Z A;  2NYP A;  2HB9 A;  4KEQ A;  2BC2 A;  3ADR A;  2BFK A;  4RAM A;  5B3R A;  1DD6 A;  1ZNB A;  3ZWF A;  2OHJ A;  3PY5 A;  2NXA A;  5ACQ A;  3PG4 A;  5ACW A;  1VME A;  3IE1 A;  4XWW A;  1JT1 A;  2Q9U A; 
#chains in the Genus database with same CATH topology
 4EY2 A;  2WYL A;  3VPE A;  2Y8B A;  5EH9 A;  1YCH A;  1ZKP A;  1Y44 A;  4XWT A;  3A4Y A;  1A7T A;  1DDK A;  1K07 A;  2CG3 A;  5A0V A;  1KO3 A;  3T3O A;  4J5F A;  1KO2 A;  4F6H A;  4C1F A;  4JO0 A;  2I7V A;  5LCH A;  5EWA A;  2VW8 A;  3IEL A;  3SBL A;  2Y87 A;  5ACT A;  3DHB A;  2FHX A;  3KNR A;  1X8I A;  2Q0I A;  1DXK A;  4AWY B;  1WUP A;  5IQK A;  4O98 A;  3BK1 A;  4D1T A;  2BR6 A;  4D1V A;  5ACS A;  4KEP A;  2ZNB A;  1YCG A;  3PY6 A;  1HLK A;  3BV6 A;  2CBN A;  5B15 A;  4C09 A;  5HIQ A;  3T3N A;  4RL2 A;  4D02 A;  4EYB A;  2YNT A;  4UA4 A;  4EFZ A;  3H3E A;  2WYM A;  5AJL A;  3SD9 A;  5AXR A;  4ZO3 A;  4Z6X A;  1L9Y A;  3SFP A;  5LS3 A;  2BG8 B;  5KIL A;  3SRX A;  5AHO A;  3IEM A;  2P1E A;  3ESH A;  5FQA A;  2CFU A;  2QDS A;  3AJ3 A;  4EYF A;  3FCZ A;  4GYU A;  4WD6 A;  3BC2 A;  4BZ3 A;  1WUO A;  2QDT A;  5EVB A;  5AEB A;  4H0D A;  1VJN A;  5A23 A;  3X2Y A;  4TYT A;  3I0V A;  3P2U A;  4D1U A;  3VQZ A;  2P4Z A;  2XR1 A;  2ZWR A;  4TZE A;  3S0Z A;  5FQB A;  1E5D A;  4NQ5 A;  1BVT A;  2Q0J A;  1KR3 A;  2I7X A;  4C1C A;  3T9M A;  5ACX A;  4V0H A;  2FU6 A;  4NQ4 A;  3IEK A;  3L6N A;  2P18 A;  4C1H A;  5HH6 A;  5EV6 A;  3ZR9 A;  5K0W A;  3DHC A;  4DIL A;  3I11 A;  2BG6 A;  3I15 A;  5AIJ A;  5EHT A;  4Z60 A;  2BMI A;  2AZ4 A;  2FU8 A;  5AXO A;  5KIK A;  4ZO2 A;  4TYF A;  5LM6 A;  2GFK A;  2FM6 A;  4RM5 A;  2NZE A;  4AXH A;  1BMC A;  5LMC A;  4C1D A;  2XF4 A;  2QJS A;  4BP0 A;  4TZ9 A;  2UYX A;  2GKL A;  2P97 A;  4YSL A;  4C1G A;  4UAM A;  4FR7 A;  3IDZ A;  2AIO A;  2BG2 A;  2OHI A;  2GCU A;  3JXP A;  3IE2 A;  4XUK A;  4AD9 A;  2H6A A;  5HIO A;  2FK6 A;  2WYM C;  4FSB A;  2ZZI A;  5HH5 A;  2WHG A;  3X2Z A;  3AF5 A;  3X2X A;  2BG8 A;  2QED A;  3DHA A;  2BGA A;  5DPX A;  4Z5Y A;  2ZO4 A;  1MQO A;  4Z67 A;  5AYA A;  2OHH A;  3Q6V A;  4HL2 A;  2YNV B;  3RKK A;  5HIS A;  5K4N A;  1XTO A;  4DIK A;  5ACU A;  2BFZ B;  2BTN A;  1QH5 A;  2CFZ A;  4YSB A;  4AX0 B;  5A87 A;  5LSC A;  3KNS A;  3FAI A;  1YCF A;  3I14 A;  4RBS A;  2FU9 A;  4LE6 A;  5EVK A;  5HIP A;  3R2U A;  3RKJ A;  5A0T A;  5ACV A;  2BFL A;  1JJT A;  3IE0 A;  4AX1 B;  3WXC A;  1WW1 A;  4UWP B;  5K4M A;  1VGN A;  2A7M A;  2DKF A;  3F9O A;  2BG7 A;  4PVO A;  3ZQ4 A;  4GCW A;  4EYL A;  2YNU A;  3IOF A;  4TZF A;  3SPU A;  1ZTC A;  1A8T A;  4AV7 A;  2Q42 A;  1JJE A;  4PVT A;  2GMN A;  3I13 A;  5LCF A;  1XM8 A;  5ACR A;  3KL7 A;  2I7T A;  3G1P A;  2R2D A;  4Z7R A;  2QIN A;  4GYQ A;  2CG2 A;  2GFJ A;  3MD7 A;  1BC2 A;  5B1U A;  2M5D A;  2YNV A;  4RL0 A;  4UWR B;  3RPC A;  1X8G A;  2FU7 A;  3SW3 A;  4D1W A;  4UBQ A;  1M2X A;  5EV8 A;  2YHE A;  4HKY A;  2BFZ A;  4RAW A;  4P62 A;  4UWS B;  5K4K A;  4B87 A;  5LE1 A;  2NZF A;  1QH3 A;  2WRS A;  3LVZ A;  5EVD A;  1X8H A;  2FHX B;  1WRA A;  4NUR A;  3DH8 A;  4J5H A;  5HH4 A;  2YZ3 A;  4ZEJ A;  4EXS A;  3BK2 A;  3X30 A;  4NQ6 A;  4HL1 A;  4FEK A;  2YNT B;  2E7Y A;  4UWO B;  4U4L A;  2Y8A A;  4AWZ A;  4F6Z A;  5EW0 A;  5ACP A;  3QH8 A;  4CHL A;  4EXY A;  1SML A;  5AHR A;  4C1E A;  2BIB A;  4NQ2 A;  5FQC A;  3TP9 A;  2YCB A;  2M5C A;  5LCA A;  4ZNB A;  2YNW A;  4YSK A;  4TZB A;  5LLD A;  3ZNB A;  2DOO A;  4PDX A;  3IOG A;  3AF6 A;  5A5Z A;  1P9E A;  4Z5Z A;  2NYP A;  2HB9 A;  4KEQ A;  2BC2 A;  3ADR A;  2BFK A;  4RAM A;  5B3R A;  1DD6 A;  1ZNB A;  3ZWF A;  2OHJ A;  3PY5 A;  2NXA A;  5ACQ A;  3PG4 A;  5ACW A;  1VME A;  3IE1 A;  4XWW A;  1JT1 A;  2Q9U A; 
#chains in the Genus database with same CATH homology
 4EY2 A;  2WYL A;  3VPE A;  2Y8B A;  5EH9 A;  1YCH A;  1ZKP A;  1Y44 A;  4XWT A;  3A4Y A;  1A7T A;  1DDK A;  1K07 A;  5A0V A;  1KO3 A;  3T3O A;  4J5F A;  1KO2 A;  4F6H A;  4C1F A;  4JO0 A;  2I7V A;  5LCH A;  5EWA A;  2VW8 A;  3IEL A;  3SBL A;  2Y87 A;  5ACT A;  3DHB A;  2FHX A;  3KNR A;  1X8I A;  2Q0I A;  1DXK A;  4AWY B;  1WUP A;  5IQK A;  4O98 A;  3BK1 A;  4D1T A;  2BR6 A;  4D1V A;  5ACS A;  4KEP A;  2ZNB A;  1YCG A;  3PY6 A;  1HLK A;  3BV6 A;  2CBN A;  5B15 A;  4C09 A;  5HIQ A;  3T3N A;  4RL2 A;  4D02 A;  4EYB A;  2YNT A;  4UA4 A;  4EFZ A;  3H3E A;  2WYM A;  3SD9 A;  5AXR A;  4ZO3 A;  4Z6X A;  1L9Y A;  3SFP A;  5LS3 A;  2BG8 B;  5KIL A;  3SRX A;  5AHO A;  3IEM A;  2P1E A;  3ESH A;  5FQA A;  2QDS A;  3AJ3 A;  4EYF A;  3FCZ A;  4GYU A;  4WD6 A;  3BC2 A;  4BZ3 A;  1WUO A;  2QDT A;  5EVB A;  5AEB A;  4H0D A;  1VJN A;  3X2Y A;  4TYT A;  3I0V A;  3P2U A;  4D1U A;  3VQZ A;  2P4Z A;  2XR1 A;  2ZWR A;  4TZE A;  3S0Z A;  5FQB A;  1E5D A;  4NQ5 A;  1BVT A;  2Q0J A;  1KR3 A;  2I7X A;  4C1C A;  3T9M A;  5ACX A;  4V0H A;  2FU6 A;  4NQ4 A;  3IEK A;  3L6N A;  2P18 A;  4C1H A;  5HH6 A;  5EV6 A;  3ZR9 A;  5K0W A;  3DHC A;  4DIL A;  3I11 A;  2BG6 A;  3I15 A;  5EHT A;  4Z60 A;  2BMI A;  2AZ4 A;  2FU8 A;  5AXO A;  5KIK A;  4ZO2 A;  4TYF A;  5LM6 A;  2GFK A;  2FM6 A;  4RM5 A;  2NZE A;  1BMC A;  5LMC A;  4C1D A;  2XF4 A;  2QJS A;  4BP0 A;  4TZ9 A;  2UYX A;  2GKL A;  2P97 A;  4YSL A;  4C1G A;  4UAM A;  4FR7 A;  3IDZ A;  2AIO A;  2BG2 A;  2OHI A;  2GCU A;  3JXP A;  3IE2 A;  4XUK A;  4AD9 A;  2H6A A;  5HIO A;  2FK6 A;  2WYM C;  4FSB A;  2ZZI A;  5HH5 A;  2WHG A;  3X2Z A;  3AF5 A;  3X2X A;  2BG8 A;  2QED A;  3DHA A;  2BGA A;  5DPX A;  4Z5Y A;  2ZO4 A;  1MQO A;  4Z67 A;  5AYA A;  2OHH A;  3Q6V A;  4HL2 A;  2YNV B;  3RKK A;  5HIS A;  5K4N A;  1XTO A;  4DIK A;  5ACU A;  2BFZ B;  2BTN A;  1QH5 A;  4YSB A;  4AX0 B;  5A87 A;  5LSC A;  3KNS A;  3FAI A;  1YCF A;  3I14 A;  4RBS A;  2FU9 A;  4LE6 A;  5EVK A;  5HIP A;  3R2U A;  3RKJ A;  5A0T A;  5ACV A;  2BFL A;  1JJT A;  3IE0 A;  4AX1 B;  3WXC A;  1WW1 A;  4UWP B;  5K4M A;  1VGN A;  2A7M A;  2DKF A;  3F9O A;  2BG7 A;  4PVO A;  3ZQ4 A;  4GCW A;  4EYL A;  2YNU A;  3IOF A;  4TZF A;  3SPU A;  1ZTC A;  1A8T A;  2Q42 A;  1JJE A;  4PVT A;  2GMN A;  3I13 A;  5LCF A;  1XM8 A;  5ACR A;  3KL7 A;  2I7T A;  3G1P A;  2R2D A;  4Z7R A;  2QIN A;  4GYQ A;  2GFJ A;  3MD7 A;  1BC2 A;  5B1U A;  2M5D A;  2YNV A;  4RL0 A;  4UWR B;  3RPC A;  1X8G A;  2FU7 A;  3SW3 A;  4D1W A;  4UBQ A;  1M2X A;  5EV8 A;  4HKY A;  2BFZ A;  4RAW A;  4P62 A;  4UWS B;  5K4K A;  4B87 A;  5LE1 A;  2NZF A;  1QH3 A;  2WRS A;  3LVZ A;  5EVD A;  1X8H A;  2FHX B;  1WRA A;  3DH8 A;  4J5H A;  5HH4 A;  2YZ3 A;  4ZEJ A;  4EXS A;  3BK2 A;  3X30 A;  4NQ6 A;  4HL1 A;  4FEK A;  2YNT B;  2E7Y A;  4UWO B;  4U4L A;  2Y8A A;  4AWZ A;  4F6Z A;  5EW0 A;  5ACP A;  3QH8 A;  4CHL A;  4EXY A;  1SML A;  5AHR A;  4C1E A;  2BIB A;  4NQ2 A;  5FQC A;  3TP9 A;  2YCB A;  2M5C A;  5LCA A;  4ZNB A;  2YNW A;  4YSK A;  4TZB A;  5LLD A;  3ZNB A;  2DOO A;  3IOG A;  3AF6 A;  5A5Z A;  1P9E A;  4Z5Z A;  2NYP A;  2HB9 A;  4KEQ A;  2BC2 A;  3ADR A;  2BFK A;  4RAM A;  5B3R A;  1DD6 A;  1ZNB A;  3ZWF A;  2OHJ A;  3PY5 A;  2NXA A;  5ACQ A;  3PG4 A;  5ACW A;  1VME A;  3IE1 A;  4XWW A;  1JT1 A;  2Q9U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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