5ACVA

Vim-2-ox, discovery of novel inhibitor scaffolds against the metallo- beta-lactamase vim-2 by spr based fragment screening
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
233
structure length
232
Chain Sequence
GEYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNRS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of Novel Inhibitor Scaffolds Against the Metallo-Beta-Lactamase Vim-2 by Spr Based Fragment Screening
pubmed doi rcsb
molecule tags Hydrolase
source organism Pseudomonas aeruginosa
molecule keywords BETA-LACTAMASE
total genus 70
structure length 232
sequence length 233
chains with identical sequence B
ec nomenclature ec 3.5.2.6: Beta-lactamase.
pdb deposition date 2015-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5acvA00
4WD6A 5ACVA 5AHOA 5EV8A 2NXAA 5LCFA 4EYLA 2I7VA 5ACTA 5ACUA 4DILA 5EH9A 4EFZA 4NQ2A 3DH8A 1M2XA 2CBNA 1KO2A 5HH5A 5AEBA 2VW8A 1ZKPA 2P18A 4AX1B 4NQ6A 3QH8A 2BG8A 2Q9UA 4U4LA 2WYMA 3FAIA 5A0TA 2Y8BA 2WRSA 3X2YA 1X8HA 3JXPA 3H3EA 3ADRA 2OHHA 4C1GA 5HIOA 4YSBA 4HKYA 3IE1A 1HLKA 4V0HA 3BV6A 2BFZA 4UWRB 4CHLA 2FK6A 4D1UA 2XF4A 2A7MA 4C1CA 5AXRA 1KO3A 4D02A 3RKJA 2UYXA 2GMNA 4Z67A 1K07A 3SD9A 3SBLA 5AXOA 2YZ3A 2QDSA 2OHJA 5EW0A 4GCWA 5ACQA 4LE6A 1WUPA 3IEMA 1JJTA 2I7XA 2BFLA 5EVBA 2YNVB 5EV6A 5EVKA 2FHXB 4Z7RA 5FQBA 4NQ5A 4RBSA 4UWPB 3I11A 5K4KA 3I15A 2BG2A 2AZ4A 3VQZA 5LMCA 4Z60A 4AWZA 4DIKA 4EYFA 2XR1A 5EVDA 3P2UA 3X30A 3SW3A 3IE0A 2YCBA 2YNWA 5ACWA 4RL0A 1A7TA 3S0ZA 4ZEJA 4XWTA 4UWOB 2YNUA 2ZNBA 3X2ZA 3BC2A 5LLDA 2GKLA 2Q0IA 3SPUA 5HISA 2GCUA 3KNRA 2QJSA 1YCGA 1VMEA 2YNVA 2BG6A 1WW1A 5KIKA 2FHXA 2FU6A 4O98A 2FU9A 3IELA 5LCHA 2YNTA 1VGNA 3ZQ4A 5EHTA 3T3OA 2BIBA 3I13A 3X2XA 4NQ4A 3MD7A 4BP0A 2BFKA 5FQCA 2WHGA 3AF6A 4KEQA 3SFPA 5A5ZA 2ZWRA 3IOFA 1MQOA 2BMIA 4Z6XA 4EYBA 1P9EA 3I14A 5AYAA 4RM5A 2DKFA 4HL2A 5K0WA 3Q6VA 2R2DA 1X8GA 1KR3A 5LE1A 4GYUA 4RAWA 3A4YA 4FR7A 1DD6A 3ZR9A 5HH6A 3PY5A 4C1EA 2FM6A 1E5DA 3PY6A 4D1WA 5B3RA 5EWAA 2BGAA 4TZEA 3ZWFA 4JO0A 5LCAA 5DPXA 2HB9A 3VPEA 5KILA 1QH3A 2WYMC 4TYTA 3IEKA 4D1TA 4YSKA 3L6NA 3TP9A 2ZZIA 4TYFA 5ACSA 3IDZA 4TZFA 4H0DA 4AD9A 1ZTCA 3BK2A 2M5CA 3DHCA 4AX0B 1WRAA 4KEPA 5K4MA 3WXCA 3IE2A 2E7YA 1BC2A 2NYPA 2BC2A 5LS3A 5IQKA 5LSCA 5FQAA 4YSLA 4C1HA 1XTOA 4FEKA 3R2UA 4XWWA 4UA4A 2BFZB 4RL2A 4RAMA 5ACRA 3PG4A 5ACXA 1Y44A 2OHIA 4EXYA 1YCFA 2WYLA 3IOGA 4D1VA 5AHRA 4TZBA 2I7TA 5A87A 3ESHA 4F6ZA 4ZO3A 4J5HA 5K4NA 4C1FA 1ZNBA 5B15A 2QDTA 1JJEA 3AJ3A 2GFJA 5HH4A 5ACPA 4EXSA 3LVZA 4J5FA 1DDKA 2BR6A 2H6AA 4UWSB 3F9OA 3KL7A 1DXKA 2QEDA 3I0VA 4BZ3A 2BTNA 4GYQA 1WUOA 1YCHA 4C1DA 4ZNBA 4AWYB 3T3NA 5HIPA 2QINA 3G1PA 4UBQA 3BK1A 4UAMA 2P97A 2NZFA 4B87A 2BG7A 2FU8A 1JT1A 3AF5A 4C09A 3DHBA 4FSBA 3SRXA 1VJNA 2NZEA 3ZNBA 1X8IA 4XUKA 1QH5A 4HL1A 2ZO4A 2AIOA 4F6HA 5A0VA 1XM8A 2DOOA 4PVOA 1SMLA 2Y87A 2Y8AA 3DHAA 2Q0JA 3RKKA 1BMCA 1BVTA 2Q42A 2P1EA 3KNSA 2YNTB 1A8TA 2BG8B 2FU7A 2M5DA 3RPCA 4P62A 5B1UA 2GFKA 4Z5YA 4Z5ZA 4TZ9A 2P4ZA 5HIQA 1L9YA 4EY2A 5LM6A 4PVTA 3FCZA 3T9MA 4ZO2A
chains in the Genus database with same CATH superfamily
4WD6A 5ACVA 5AHOA 5EV8A 4AXHA 2NXAA 5LCFA 4EYLA 2I7VA 5ACTA 5ACUA 4DILA 5EH9A 4EFZA 4NQ2A 3DH8A 1M2XA 2CBNA 1KO2A 5HH5A 5AEBA 2VW8A 1ZKPA 2P18A 4AX1B 4NQ6A 3QH8A 2BG8A 2Q9UA 4U4LA 2WYMA 3FAIA 5A0TA 2Y8BA 2WRSA 3X2YA 1X8HA 3JXPA 3H3EA 3ADRA 2OHHA 4C1GA 5HIOA 4NURA 4YSBA 4HKYA 3IE1A 1HLKA 4V0HA 3BV6A 2BFZA 4UWRB 4CHLA 2FK6A 4D1UA 2XF4A 2A7MA 4C1CA 5AXRA 1KO3A 4D02A 3RKJA 2UYXA 2GMNA 4Z67A 1K07A 3SD9A 3SBLA 5AXOA 2YZ3A 2QDSA 2OHJA 5EW0A 4GCWA 5ACQA 4LE6A 4PDXA 1WUPA 3IEMA 1JJTA 2I7XA 2BFLA 5EVBA 2YNVB 5EV6A 5EVKA 2CG3A 2FHXB 4Z7RA 5FQBA 4NQ5A 4RBSA 4UWPB 3I11A 5K4KA 3I15A 2BG2A 2AZ4A 3VQZA 5LMCA 4Z60A 4AWZA 4DIKA 4EYFA 2XR1A 5EVDA 2CG2A 3P2UA 3X30A 3SW3A 3IE0A 2YCBA 2YNWA 5ACWA 4RL0A 1A7TA 3S0ZA 4ZEJA 4XWTA 4UWOB 2YNUA 2ZNBA 3X2ZA 3BC2A 5LLDA 2GKLA 2Q0IA 3SPUA 5HISA 2GCUA 3KNRA 2QJSA 1YCGA 1VMEA 2YNVA 2BG6A 1WW1A 5KIKA 2FHXA 2FU6A 4O98A 2FU9A 3IELA 5LCHA 2YNTA 1VGNA 3ZQ4A 5EHTA 3T3OA 2BIBA 3I13A 3X2XA 4NQ4A 3MD7A 4BP0A 2BFKA 5FQCA 2WHGA 3AF6A 4KEQA 3SFPA 5A5ZA 2ZWRA 3IOFA 1MQOA 2BMIA 4Z6XA 4EYBA 1P9EA 3I14A 5AYAA 4RM5A 2DKFA 4HL2A 5K0WA 3Q6VA 2R2DA 1X8GA 1KR3A 5LE1A 5AJLA 4GYUA 4RAWA 3A4YA 4FR7A 1DD6A 3ZR9A 5HH6A 3PY5A 4C1EA 5AIJA 2FM6A 1E5DA 3PY6A 4D1WA 2CFUA 5B3RA 5EWAA 2BGAA 4TZEA 3ZWFA 4JO0A 5LCAA 5DPXA 2HB9A 3VPEA 5KILA 1QH3A 2WYMC 4TYTA 2YHEA 3IEKA 4D1TA 4YSKA 3L6NA 3TP9A 2ZZIA 4TYFA 5ACSA 3IDZA 4TZFA 4H0DA 4AD9A 1ZTCA 3BK2A 2M5CA 3DHCA 4AX0B 1WRAA 4KEPA 5K4MA 3WXCA 3IE2A 2E7YA 1BC2A 2NYPA 2BC2A 5LS3A 5IQKA 5LSCA 5FQAA 4YSLA 4C1HA 1XTOA 4FEKA 4AV7A 3R2UA 4XWWA 4UA4A 2BFZB 4RL2A 4RAMA 5ACRA 3PG4A 5ACXA 1Y44A 2OHIA 4EXYA 1YCFA 2WYLA 3IOGA 4D1VA 5AHRA 4TZBA 2I7TA 5A87A 3ESHA 4F6ZA 4ZO3A 4J5HA 5K4NA 4C1FA 1ZNBA 5B15A 2QDTA 1JJEA 3AJ3A 2GFJA 5HH4A 5ACPA 4EXSA 3LVZA 4J5FA 1DDKA 2BR6A 2H6AA 4UWSB 3F9OA 3KL7A 1DXKA 2QEDA 3I0VA 4BZ3A 2BTNA 4GYQA 1WUOA 1YCHA 4C1DA 4ZNBA 4AWYB 3T3NA 5HIPA 2QINA 3G1PA 4UBQA 3BK1A 4UAMA 2P97A 2NZFA 4B87A 2BG7A 2FU8A 1JT1A 3AF5A 4C09A 3DHBA 4FSBA 3SRXA 5A23A 1VJNA 2NZEA 3ZNBA 1X8IA 4XUKA 1QH5A 4HL1A 2ZO4A 2AIOA 4F6HA 5A0VA 1XM8A 2DOOA 4PVOA 1SMLA 2Y87A 2Y8AA 3DHAA 2CFZA 2Q0JA 3RKKA 1BMCA 1BVTA 2Q42A 2P1EA 3KNSA 2YNTB 1A8TA 2BG8B 2FU7A 2M5DA 3RPCA 4P62A 5B1UA 2GFKA 4Z5YA 4Z5ZA 4TZ9A 2P4ZA 5HIQA 1L9YA 4EY2A 5LM6A 4PVTA 3FCZA 3T9MA 4ZO2A
chains in the Genus database with same CATH topology
4WD6A 5ACVA 5AHOA 5EV8A 2NXAA 5LCFA 4EYLA 2I7VA 5ACTA 5ACUA 4DILA 5EH9A 4EFZA 4NQ2A 3DH8A 1M2XA 2CBNA 1KO2A 5HH5A 5AEBA 2VW8A 1ZKPA 2P18A 4AX1B 4NQ6A 3QH8A 2BG8A 2Q9UA 4U4LA 2WYMA 3FAIA 5A0TA 2Y8BA 2WRSA 3X2YA 1X8HA 3JXPA 3H3EA 3ADRA 2OHHA 4C1GA 5HIOA 4YSBA 4HKYA 3IE1A 1HLKA 4V0HA 3BV6A 2BFZA 4UWRB 4CHLA 2FK6A 4D1UA 2XF4A 2A7MA 4C1CA 5AXRA 1KO3A 4D02A 3RKJA 2UYXA 2GMNA 4Z67A 1K07A 3SD9A 3SBLA 5AXOA 2YZ3A 2QDSA 2OHJA 5EW0A 4GCWA 5ACQA 4LE6A 1WUPA 3IEMA 1JJTA 2I7XA 2BFLA 5EVBA 2YNVB 5EV6A 5EVKA 2FHXB 4Z7RA 5FQBA 4NQ5A 4RBSA 4UWPB 3I11A 5K4KA 3I15A 2BG2A 2AZ4A 3VQZA 5LMCA 4Z60A 4AWZA 4DIKA 4EYFA 2XR1A 5EVDA 3P2UA 3X30A 3SW3A 3IE0A 2YCBA 2YNWA 5ACWA 4RL0A 1A7TA 3S0ZA 4ZEJA 4XWTA 4UWOB 2YNUA 2ZNBA 3X2ZA 3BC2A 5LLDA 2GKLA 2Q0IA 3SPUA 5HISA 2GCUA 3KNRA 2QJSA 1YCGA 1VMEA 2YNVA 2BG6A 1WW1A 5KIKA 2FHXA 2FU6A 4O98A 2FU9A 3IELA 5LCHA 2YNTA 1VGNA 3ZQ4A 5EHTA 3T3OA 2BIBA 3I13A 3X2XA 4NQ4A 3MD7A 4BP0A 2BFKA 5FQCA 2WHGA 3AF6A 4KEQA 3SFPA 5A5ZA 2ZWRA 3IOFA 1MQOA 2BMIA 4Z6XA 4EYBA 1P9EA 3I14A 5AYAA 4RM5A 2DKFA 4HL2A 5K0WA 3Q6VA 2R2DA 1X8GA 1KR3A 5LE1A 4GYUA 4RAWA 3A4YA 4FR7A 1DD6A 3ZR9A 5HH6A 3PY5A 4C1EA 2FM6A 1E5DA 3PY6A 4D1WA 5B3RA 5EWAA 2BGAA 4TZEA 3ZWFA 4JO0A 5LCAA 5DPXA 2HB9A 3VPEA 5KILA 1QH3A 2WYMC 4TYTA 3IEKA 4D1TA 4YSKA 3L6NA 3TP9A 2ZZIA 4TYFA 5ACSA 3IDZA 4TZFA 4H0DA 4AD9A 1ZTCA 3BK2A 2M5CA 3DHCA 4AX0B 1WRAA 4KEPA 5K4MA 3WXCA 3IE2A 2E7YA 1BC2A 2NYPA 2BC2A 5LS3A 5IQKA 5LSCA 5FQAA 4YSLA 4C1HA 1XTOA 4FEKA 3R2UA 4XWWA 4UA4A 2BFZB 4RL2A 4RAMA 5ACRA 3PG4A 5ACXA 1Y44A 2OHIA 4EXYA 1YCFA 2WYLA 3IOGA 4D1VA 5AHRA 4TZBA 2I7TA 5A87A 3ESHA 4F6ZA 4ZO3A 4J5HA 5K4NA 4C1FA 1ZNBA 5B15A 2QDTA 1JJEA 3AJ3A 2GFJA 5HH4A 5ACPA 4EXSA 3LVZA 4J5FA 1DDKA 2BR6A 2H6AA 4UWSB 3F9OA 3KL7A 1DXKA 2QEDA 3I0VA 4BZ3A 2BTNA 4GYQA 1WUOA 1YCHA 4C1DA 4ZNBA 4AWYB 3T3NA 5HIPA 2QINA 3G1PA 4UBQA 3BK1A 4UAMA 2P97A 2NZFA 4B87A 2BG7A 2FU8A 1JT1A 3AF5A 4C09A 3DHBA 4FSBA 3SRXA 1VJNA 2NZEA 3ZNBA 1X8IA 4XUKA 1QH5A 4HL1A 2ZO4A 2AIOA 4F6HA 5A0VA 1XM8A 2DOOA 4PVOA 1SMLA 2Y87A 2Y8AA 3DHAA 2Q0JA 3RKKA 1BMCA 1BVTA 2Q42A 2P1EA 3KNSA 2YNTB 1A8TA 2BG8B 2FU7A 2M5DA 3RPCA 4P62A 5B1UA 2GFKA 4Z5YA 4Z5ZA 4TZ9A 2P4ZA 5HIQA 1L9YA 4EY2A 5LM6A 4PVTA 3FCZA 3T9MA 4ZO2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WD6 A;  5ACV A;  5AHO A;  5EV8 A;  2NXA A;  5LCF A;  4EYL A;  2I7V A;  5ACT A;  5ACU A;  4DIL A;  5EH9 A;  4EFZ A;  4NQ2 A;  3DH8 A;  1M2X A;  2CBN A;  1KO2 A;  5HH5 A;  5AEB A;  2VW8 A;  1ZKP A;  2P18 A;  4AX1 B;  4NQ6 A;  3QH8 A;  2BG8 A;  2Q9U A;  4U4L A;  2WYM A;  3FAI A;  5A0T A;  2Y8B A;  2WRS A;  3X2Y A;  1X8H A;  3JXP A;  3H3E A;  3ADR A;  2OHH A;  4C1G A;  5HIO A;  4YSB A;  4HKY A;  3IE1 A;  1HLK A;  4V0H A;  3BV6 A;  2BFZ A;  4UWR B;  4CHL A;  2FK6 A;  4D1U A;  2XF4 A;  2A7M A;  4C1C A;  5AXR A;  1KO3 A;  4D02 A;  3RKJ A;  2UYX A;  2GMN A;  4Z67 A;  1K07 A;  3SD9 A;  3SBL A;  5AXO A;  2YZ3 A;  2QDS A;  2OHJ A;  5EW0 A;  4GCW A;  5ACQ A;  4LE6 A;  1WUP A;  3IEM A;  1JJT A;  2I7X A;  2BFL A;  5EVB A;  2YNV B;  5EV6 A;  5EVK A;  2FHX B;  4Z7R A;  5FQB A;  4NQ5 A;  4RBS A;  4UWP B;  3I11 A;  5K4K A;  3I15 A;  2BG2 A;  2AZ4 A;  3VQZ A;  5LMC A;  4Z60 A;  4AWZ A;  4DIK A;  4EYF A;  2XR1 A;  5EVD A;  3P2U A;  3X30 A;  3SW3 A;  3IE0 A;  2YCB A;  2YNW A;  5ACW A;  4RL0 A;  1A7T A;  3S0Z A;  4ZEJ A;  4XWT A;  4UWO B;  2YNU A;  2ZNB A;  3X2Z A;  3BC2 A;  5LLD A;  2GKL A;  2Q0I A;  3SPU A;  5HIS A;  2GCU A;  3KNR A;  2QJS A;  1YCG A;  1VME A;  2YNV A;  2BG6 A;  1WW1 A;  5KIK A;  2FHX A;  2FU6 A;  4O98 A;  2FU9 A;  3IEL A;  5LCH A;  2YNT A;  1VGN A;  3ZQ4 A;  5EHT A;  3T3O A;  2BIB A;  3I13 A;  3X2X A;  4NQ4 A;  3MD7 A;  4BP0 A;  2BFK A;  5FQC A;  2WHG A;  3AF6 A;  4KEQ A;  3SFP A;  5A5Z A;  2ZWR A;  3IOF A;  1MQO A;  2BMI A;  4Z6X A;  4EYB A;  1P9E A;  3I14 A;  5AYA A;  4RM5 A;  2DKF A;  4HL2 A;  5K0W A;  3Q6V A;  2R2D A;  1X8G A;  1KR3 A;  5LE1 A;  4GYU A;  4RAW A;  3A4Y A;  4FR7 A;  1DD6 A;  3ZR9 A;  5HH6 A;  3PY5 A;  4C1E A;  2FM6 A;  1E5D A;  3PY6 A;  4D1W A;  5B3R A;  5EWA A;  2BGA A;  4TZE A;  3ZWF A;  4JO0 A;  5LCA A;  5DPX A;  2HB9 A;  3VPE A;  5KIL A;  1QH3 A;  2WYM C;  4TYT A;  3IEK A;  4D1T A;  4YSK A;  3L6N A;  3TP9 A;  2ZZI A;  4TYF A;  5ACS A;  3IDZ A;  4TZF A;  4H0D A;  4AD9 A;  1ZTC A;  3BK2 A;  2M5C A;  3DHC A;  4AX0 B;  1WRA A;  4KEP A;  5K4M A;  3WXC A;  3IE2 A;  2E7Y A;  1BC2 A;  2NYP A;  2BC2 A;  5LS3 A;  5IQK A;  5LSC A;  5FQA A;  4YSL A;  4C1H A;  1XTO A;  4FEK A;  3R2U A;  4XWW A;  4UA4 A;  2BFZ B;  4RL2 A;  4RAM A;  5ACR A;  3PG4 A;  5ACX A;  1Y44 A;  2OHI A;  4EXY A;  1YCF A;  2WYL A;  3IOG A;  4D1V A;  5AHR A;  4TZB A;  2I7T A;  5A87 A;  3ESH A;  4F6Z A;  4ZO3 A;  4J5H A;  5K4N A;  4C1F A;  1ZNB A;  5B15 A;  2QDT A;  1JJE A;  3AJ3 A;  2GFJ A;  5HH4 A;  5ACP A;  4EXS A;  3LVZ A;  4J5F A;  1DDK A;  2BR6 A;  2H6A A;  4UWS B;  3F9O A;  3KL7 A;  1DXK A;  2QED A;  3I0V A;  4BZ3 A;  2BTN A;  4GYQ A;  1WUO A;  1YCH A;  4C1D A;  4ZNB A;  4AWY B;  3T3N A;  5HIP A;  2QIN A;  3G1P A;  4UBQ A;  3BK1 A;  4UAM A;  2P97 A;  2NZF A;  4B87 A;  2BG7 A;  2FU8 A;  1JT1 A;  3AF5 A;  4C09 A;  3DHB A;  4FSB A;  3SRX A;  1VJN A;  2NZE A;  3ZNB A;  1X8I A;  4XUK A;  1QH5 A;  4HL1 A;  2ZO4 A;  2AIO A;  4F6H A;  5A0V A;  1XM8 A;  2DOO A;  4PVO A;  1SML A;  2Y87 A;  2Y8A A;  3DHA A;  2Q0J A;  3RKK A;  1BMC A;  1BVT A;  2Q42 A;  2P1E A;  3KNS A;  2YNT B;  1A8T A;  2BG8 B;  2FU7 A;  2M5D A;  3RPC A;  4P62 A;  5B1U A;  2GFK A;  4Z5Y A;  4Z5Z A;  4TZ9 A;  2P4Z A;  5HIQ A;  1L9Y A;  4EY2 A;  5LM6 A;  4PVT A;  3FCZ A;  3T9M A;  4ZO2 A; 
#chains in the Genus database with same CATH topology
 4WD6 A;  5ACV A;  5AHO A;  5EV8 A;  4AXH A;  2NXA A;  5LCF A;  4EYL A;  2I7V A;  5ACT A;  5ACU A;  4DIL A;  5EH9 A;  4EFZ A;  4NQ2 A;  3DH8 A;  1M2X A;  2CBN A;  1KO2 A;  5HH5 A;  5AEB A;  2VW8 A;  1ZKP A;  2P18 A;  4AX1 B;  4NQ6 A;  3QH8 A;  2BG8 A;  2Q9U A;  4U4L A;  2WYM A;  3FAI A;  5A0T A;  2Y8B A;  2WRS A;  3X2Y A;  1X8H A;  3JXP A;  3H3E A;  3ADR A;  2OHH A;  4C1G A;  5HIO A;  4NUR A;  4YSB A;  4HKY A;  3IE1 A;  1HLK A;  4V0H A;  3BV6 A;  2BFZ A;  4UWR B;  4CHL A;  2FK6 A;  4D1U A;  2XF4 A;  2A7M A;  4C1C A;  5AXR A;  1KO3 A;  4D02 A;  3RKJ A;  2UYX A;  2GMN A;  4Z67 A;  1K07 A;  3SD9 A;  3SBL A;  5AXO A;  2YZ3 A;  2QDS A;  2OHJ A;  5EW0 A;  4GCW A;  5ACQ A;  4LE6 A;  4PDX A;  1WUP A;  3IEM A;  1JJT A;  2I7X A;  2BFL A;  5EVB A;  2YNV B;  5EV6 A;  5EVK A;  2CG3 A;  2FHX B;  4Z7R A;  5FQB A;  4NQ5 A;  4RBS A;  4UWP B;  3I11 A;  5K4K A;  3I15 A;  2BG2 A;  2AZ4 A;  3VQZ A;  5LMC A;  4Z60 A;  4AWZ A;  4DIK A;  4EYF A;  2XR1 A;  5EVD A;  2CG2 A;  3P2U A;  3X30 A;  3SW3 A;  3IE0 A;  2YCB A;  2YNW A;  5ACW A;  4RL0 A;  1A7T A;  3S0Z A;  4ZEJ A;  4XWT A;  4UWO B;  2YNU A;  2ZNB A;  3X2Z A;  3BC2 A;  5LLD A;  2GKL A;  2Q0I A;  3SPU A;  5HIS A;  2GCU A;  3KNR A;  2QJS A;  1YCG A;  1VME A;  2YNV A;  2BG6 A;  1WW1 A;  5KIK A;  2FHX A;  2FU6 A;  4O98 A;  2FU9 A;  3IEL A;  5LCH A;  2YNT A;  1VGN A;  3ZQ4 A;  5EHT A;  3T3O A;  2BIB A;  3I13 A;  3X2X A;  4NQ4 A;  3MD7 A;  4BP0 A;  2BFK A;  5FQC A;  2WHG A;  3AF6 A;  4KEQ A;  3SFP A;  5A5Z A;  2ZWR A;  3IOF A;  1MQO A;  2BMI A;  4Z6X A;  4EYB A;  1P9E A;  3I14 A;  5AYA A;  4RM5 A;  2DKF A;  4HL2 A;  5K0W A;  3Q6V A;  2R2D A;  1X8G A;  1KR3 A;  5LE1 A;  5AJL A;  4GYU A;  4RAW A;  3A4Y A;  4FR7 A;  1DD6 A;  3ZR9 A;  5HH6 A;  3PY5 A;  4C1E A;  5AIJ A;  2FM6 A;  1E5D A;  3PY6 A;  4D1W A;  2CFU A;  5B3R A;  5EWA A;  2BGA A;  4TZE A;  3ZWF A;  4JO0 A;  5LCA A;  5DPX A;  2HB9 A;  3VPE A;  5KIL A;  1QH3 A;  2WYM C;  4TYT A;  2YHE A;  3IEK A;  4D1T A;  4YSK A;  3L6N A;  3TP9 A;  2ZZI A;  4TYF A;  5ACS A;  3IDZ A;  4TZF A;  4H0D A;  4AD9 A;  1ZTC A;  3BK2 A;  2M5C A;  3DHC A;  4AX0 B;  1WRA A;  4KEP A;  5K4M A;  3WXC A;  3IE2 A;  2E7Y A;  1BC2 A;  2NYP A;  2BC2 A;  5LS3 A;  5IQK A;  5LSC A;  5FQA A;  4YSL A;  4C1H A;  1XTO A;  4FEK A;  4AV7 A;  3R2U A;  4XWW A;  4UA4 A;  2BFZ B;  4RL2 A;  4RAM A;  5ACR A;  3PG4 A;  5ACX A;  1Y44 A;  2OHI A;  4EXY A;  1YCF A;  2WYL A;  3IOG A;  4D1V A;  5AHR A;  4TZB A;  2I7T A;  5A87 A;  3ESH A;  4F6Z A;  4ZO3 A;  4J5H A;  5K4N A;  4C1F A;  1ZNB A;  5B15 A;  2QDT A;  1JJE A;  3AJ3 A;  2GFJ A;  5HH4 A;  5ACP A;  4EXS A;  3LVZ A;  4J5F A;  1DDK A;  2BR6 A;  2H6A A;  4UWS B;  3F9O A;  3KL7 A;  1DXK A;  2QED A;  3I0V A;  4BZ3 A;  2BTN A;  4GYQ A;  1WUO A;  1YCH A;  4C1D A;  4ZNB A;  4AWY B;  3T3N A;  5HIP A;  2QIN A;  3G1P A;  4UBQ A;  3BK1 A;  4UAM A;  2P97 A;  2NZF A;  4B87 A;  2BG7 A;  2FU8 A;  1JT1 A;  3AF5 A;  4C09 A;  3DHB A;  4FSB A;  3SRX A;  5A23 A;  1VJN A;  2NZE A;  3ZNB A;  1X8I A;  4XUK A;  1QH5 A;  4HL1 A;  2ZO4 A;  2AIO A;  4F6H A;  5A0V A;  1XM8 A;  2DOO A;  4PVO A;  1SML A;  2Y87 A;  2Y8A A;  3DHA A;  2CFZ A;  2Q0J A;  3RKK A;  1BMC A;  1BVT A;  2Q42 A;  2P1E A;  3KNS A;  2YNT B;  1A8T A;  2BG8 B;  2FU7 A;  2M5D A;  3RPC A;  4P62 A;  5B1U A;  2GFK A;  4Z5Y A;  4Z5Z A;  4TZ9 A;  2P4Z A;  5HIQ A;  1L9Y A;  4EY2 A;  5LM6 A;  4PVT A;  3FCZ A;  3T9M A;  4ZO2 A; 
#chains in the Genus database with same CATH homology
 4WD6 A;  5ACV A;  5AHO A;  5EV8 A;  2NXA A;  5LCF A;  4EYL A;  2I7V A;  5ACT A;  5ACU A;  4DIL A;  5EH9 A;  4EFZ A;  4NQ2 A;  3DH8 A;  1M2X A;  2CBN A;  1KO2 A;  5HH5 A;  5AEB A;  2VW8 A;  1ZKP A;  2P18 A;  4AX1 B;  4NQ6 A;  3QH8 A;  2BG8 A;  2Q9U A;  4U4L A;  2WYM A;  3FAI A;  5A0T A;  2Y8B A;  2WRS A;  3X2Y A;  1X8H A;  3JXP A;  3H3E A;  3ADR A;  2OHH A;  4C1G A;  5HIO A;  4YSB A;  4HKY A;  3IE1 A;  1HLK A;  4V0H A;  3BV6 A;  2BFZ A;  4UWR B;  4CHL A;  2FK6 A;  4D1U A;  2XF4 A;  2A7M A;  4C1C A;  5AXR A;  1KO3 A;  4D02 A;  3RKJ A;  2UYX A;  2GMN A;  4Z67 A;  1K07 A;  3SD9 A;  3SBL A;  5AXO A;  2YZ3 A;  2QDS A;  2OHJ A;  5EW0 A;  4GCW A;  5ACQ A;  4LE6 A;  1WUP A;  3IEM A;  1JJT A;  2I7X A;  2BFL A;  5EVB A;  2YNV B;  5EV6 A;  5EVK A;  2FHX B;  4Z7R A;  5FQB A;  4NQ5 A;  4RBS A;  4UWP B;  3I11 A;  5K4K A;  3I15 A;  2BG2 A;  2AZ4 A;  3VQZ A;  5LMC A;  4Z60 A;  4AWZ A;  4DIK A;  4EYF A;  2XR1 A;  5EVD A;  3P2U A;  3X30 A;  3SW3 A;  3IE0 A;  2YCB A;  2YNW A;  5ACW A;  4RL0 A;  1A7T A;  3S0Z A;  4ZEJ A;  4XWT A;  4UWO B;  2YNU A;  2ZNB A;  3X2Z A;  3BC2 A;  5LLD A;  2GKL A;  2Q0I A;  3SPU A;  5HIS A;  2GCU A;  3KNR A;  2QJS A;  1YCG A;  1VME A;  2YNV A;  2BG6 A;  1WW1 A;  5KIK A;  2FHX A;  2FU6 A;  4O98 A;  2FU9 A;  3IEL A;  5LCH A;  2YNT A;  1VGN A;  3ZQ4 A;  5EHT A;  3T3O A;  2BIB A;  3I13 A;  3X2X A;  4NQ4 A;  3MD7 A;  4BP0 A;  2BFK A;  5FQC A;  2WHG A;  3AF6 A;  4KEQ A;  3SFP A;  5A5Z A;  2ZWR A;  3IOF A;  1MQO A;  2BMI A;  4Z6X A;  4EYB A;  1P9E A;  3I14 A;  5AYA A;  4RM5 A;  2DKF A;  4HL2 A;  5K0W A;  3Q6V A;  2R2D A;  1X8G A;  1KR3 A;  5LE1 A;  4GYU A;  4RAW A;  3A4Y A;  4FR7 A;  1DD6 A;  3ZR9 A;  5HH6 A;  3PY5 A;  4C1E A;  2FM6 A;  1E5D A;  3PY6 A;  4D1W A;  5B3R A;  5EWA A;  2BGA A;  4TZE A;  3ZWF A;  4JO0 A;  5LCA A;  5DPX A;  2HB9 A;  3VPE A;  5KIL A;  1QH3 A;  2WYM C;  4TYT A;  3IEK A;  4D1T A;  4YSK A;  3L6N A;  3TP9 A;  2ZZI A;  4TYF A;  5ACS A;  3IDZ A;  4TZF A;  4H0D A;  4AD9 A;  1ZTC A;  3BK2 A;  2M5C A;  3DHC A;  4AX0 B;  1WRA A;  4KEP A;  5K4M A;  3WXC A;  3IE2 A;  2E7Y A;  1BC2 A;  2NYP A;  2BC2 A;  5LS3 A;  5IQK A;  5LSC A;  5FQA A;  4YSL A;  4C1H A;  1XTO A;  4FEK A;  3R2U A;  4XWW A;  4UA4 A;  2BFZ B;  4RL2 A;  4RAM A;  5ACR A;  3PG4 A;  5ACX A;  1Y44 A;  2OHI A;  4EXY A;  1YCF A;  2WYL A;  3IOG A;  4D1V A;  5AHR A;  4TZB A;  2I7T A;  5A87 A;  3ESH A;  4F6Z A;  4ZO3 A;  4J5H A;  5K4N A;  4C1F A;  1ZNB A;  5B15 A;  2QDT A;  1JJE A;  3AJ3 A;  2GFJ A;  5HH4 A;  5ACP A;  4EXS A;  3LVZ A;  4J5F A;  1DDK A;  2BR6 A;  2H6A A;  4UWS B;  3F9O A;  3KL7 A;  1DXK A;  2QED A;  3I0V A;  4BZ3 A;  2BTN A;  4GYQ A;  1WUO A;  1YCH A;  4C1D A;  4ZNB A;  4AWY B;  3T3N A;  5HIP A;  2QIN A;  3G1P A;  4UBQ A;  3BK1 A;  4UAM A;  2P97 A;  2NZF A;  4B87 A;  2BG7 A;  2FU8 A;  1JT1 A;  3AF5 A;  4C09 A;  3DHB A;  4FSB A;  3SRX A;  1VJN A;  2NZE A;  3ZNB A;  1X8I A;  4XUK A;  1QH5 A;  4HL1 A;  2ZO4 A;  2AIO A;  4F6H A;  5A0V A;  1XM8 A;  2DOO A;  4PVO A;  1SML A;  2Y87 A;  2Y8A A;  3DHA A;  2Q0J A;  3RKK A;  1BMC A;  1BVT A;  2Q42 A;  2P1E A;  3KNS A;  2YNT B;  1A8T A;  2BG8 B;  2FU7 A;  2M5D A;  3RPC A;  4P62 A;  5B1U A;  2GFK A;  4Z5Y A;  4Z5Z A;  4TZ9 A;  2P4Z A;  5HIQ A;  1L9Y A;  4EY2 A;  5LM6 A;  4PVT A;  3FCZ A;  3T9M A;  4ZO2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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