5ACWA

Vim-2-1, discovery of novel inhibitor scaffolds against the metallo- beta-lactamase vim-2 by spr based fragment screening
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
233
structure length
232
Chain Sequence
GEYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNRS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords BETA-LACTAMASE
publication title Discovery of Novel Inhibitor Scaffolds Against the Metallo-Beta-Lactamase Vim-2 by Spr Based Fragment Screening
pubmed doi rcsb
source organism Pseudomonas aeruginosa
total genus 73
structure length 232
sequence length 233
chains with identical sequence B
ec nomenclature ec 3.5.2.6: Beta-lactamase.
pdb deposition date 2015-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5acwA00
4NQ5A 4RL0A 2UYXA 5LCAA 4UWOB 2QJSA 2YZ3A 2YNVA 1A7TA 4TYFA 4EYBA 4P62A 4F6HA 5EVBA 3AF5A 4D1WA 1M2XA 4J5FA 2GCUA 4HKYA 4D02A 5AHRA 2OHHA 3BV6A 1BC2A 2BFLA 5B15A 2NZFA 5AEBA 4Z5ZA 3RKKA 1ZTCA 5KILA 4AWYB 2HB9A 4FEKA 4D1VA 5KIKA 2FU8A 1DXKA 4KEPA 3FAIA 2Q0JA 4GCWA 5A0VA 5EVKA 3F9OA 5LMCA 2WYMC 4DILA 3IEKA 4RAMA 4UWSB 2FU6A 4C1FA 5FQAA 5ACXA 4WD6A 4GYQA 3IOFA 4GYUA 4FSBA 4O98A 5K0WA 4Z5YA 3WXCA 4UAMA 3X2ZA 3TP9A 4UA4A 5HISA 2CBNA 4BP0A 2YNTB 4TZEA 3ZWFA 4C1CA 5AHOA 4C1GA 3KNSA 4UWRB 3BK1A 4C1EA 3Q6VA 1KO2A 3KNRA 4EYLA 2NZEA 4HL1A 4UWPB 3VQZA 2Q9UA 4ZNBA 3AJ3A 1P9EA 2BMIA 4D1UA 2FK6A 5ACSA 4PVOA 4XWTA 3SBLA 5DPXA 3SRXA 4H0DA 4D1TA 4AWZA 2Y8BA 2BG7A 5EW0A 5IQKA 4B87A 2AIOA 1L9YA 2YNUA 1WW1A 4NQ2A 4NQ6A 2Y87A 3AF6A 2NXAA 3IEMA 2GFJA 5A87A 1JJTA 3JXPA 2ZZIA 4FR7A 3SW3A 2FHXA 1K07A 1SMLA 2I7TA 3ADRA 5A0TA 1QH3A 5ACQA 3X2XA 4Z7RA 2VW8A 4EXSA 2YCBA 3ESHA 4AD9A 1A8TA 1DDKA 4U4LA 3DHAA 3IE2A 4ZO3A 3T3OA 2DOOA 4YSBA 2BGAA 3ZQ4A 2ZWRA 1KO3A 2WHGA 5K4KA 2A7MA 2Y8AA 2H6AA 3I0VA 4RBSA 2BG8B 2QINA 4XWWA 3R2UA 3DH8A 3RPCA 4TZBA 1WUOA 5AYAA 2M5DA 1X8IA 1X8HA 4UBQA 5HH5A 4EY2A 5EVDA 2BFKA 4HL2A 2QDTA 5EV8A 5B3RA 2QEDA 2GMNA 5HIQA 5K4MA 4ZO2A 3ZR9A 3SPUA 3I11A 3G1PA 1XM8A 3A4YA 4J5HA 1WRAA 3BC2A 5HIPA 4NQ4A 2GKLA 3H3EA 2YNTA 2E7YA 3FCZA 1BVTA 4AX0B 3SFPA 2DKFA 3I13A 4RAWA 4CHLA 2BR6A 2FU7A 1XTOA 2BIBA 1BMCA 3RKJA 3MD7A 2BG2A 1MQOA 1JT1A 1WUPA 3P2UA 5EV6A 5ACPA 5HH4A 4RL2A 4V0HA 5EWAA 4Z60A 2YNVB 5AXRA 4TZFA 3BK2A 4TYTA 4YSKA 4LE6A 2I7XA 5ACUA 1Y44A 3PY6A 5ACRA 3IDZA 2R2DA 1HLKA 4ZEJA 2WRSA 5FQCA 3DHCA 4AX1B 5HIOA 2NYPA 5LE1A 5EHTA 1JJEA 5AXOA 4YSLA 2GFKA 3S0ZA 4F6ZA 3PG4A 4EXYA 5LSCA 4JO0A 5B1UA 2P97A 2ZNBA 1YCGA 2BC2A 1ZNBA 5LCFA 2YNWA 2P18A 4XUKA 1VMEA 2OHJA 2BG8A 3ZNBA 5ACVA 5EH9A 1YCHA 1E5DA 2XF4A 4KEQA 2XR1A 2FM6A 3T9MA 4C09A 1QH5A 3IE0A 3T3NA 1VGNA 4EFZA 4BZ3A 3KL7A 2Q0IA 2P1EA 3X30A 3IE1A 1X8GA 1YCFA 2QDSA 2ZO4A 2WYMA 2OHIA 5K4NA 4Z6XA 3LVZA 3I14A 1VJNA 4C1DA 5LS3A 3IELA 2BFZB 2I7VA 4C1HA 2P4ZA 5FQBA 2WYLA 1ZKPA 3DHBA 5LM6A 5A5ZA 2BG6A 4RM5A 3VPEA 5HH6A 3X2YA 5ACWA 4TZ9A 5LCHA 1KR3A 3QH8A 2BFZA 2FU9A 2FHXB 1DD6A 4Z67A 2AZ4A 5ACTA 4EYFA 4PVTA 2M5CA 2Q42A 5LLDA 3I15A 3PY5A 2BTNA 3SD9A 3IOGA 4DIKA 3L6NA
chains in the Genus database with same CATH superfamily
4NQ5A 4RL0A 2UYXA 5LCAA 4UWOB 2QJSA 2YZ3A 2YNVA 1A7TA 4TYFA 4EYBA 4P62A 4F6HA 5EVBA 3AF5A 4D1WA 1M2XA 4J5FA 2GCUA 4HKYA 4D02A 5AHRA 2OHHA 3BV6A 1BC2A 2BFLA 5B15A 2NZFA 5AEBA 4Z5ZA 3RKKA 1ZTCA 5KILA 4AWYB 2HB9A 4FEKA 4D1VA 5KIKA 2FU8A 1DXKA 4KEPA 3FAIA 2Q0JA 4GCWA 5A0VA 5EVKA 3F9OA 5LMCA 2WYMC 4DILA 3IEKA 4RAMA 4UWSB 2FU6A 4C1FA 5FQAA 5ACXA 4WD6A 4GYQA 3IOFA 4GYUA 4FSBA 4O98A 5K0WA 4Z5YA 3WXCA 4UAMA 3X2ZA 3TP9A 4UA4A 5HISA 2CBNA 4BP0A 2YNTB 4TZEA 3ZWFA 4C1CA 5AHOA 4C1GA 3KNSA 4UWRB 3BK1A 4C1EA 3Q6VA 1KO2A 3KNRA 4EYLA 2NZEA 4HL1A 4UWPB 3VQZA 2Q9UA 4ZNBA 3AJ3A 1P9EA 2BMIA 4D1UA 2FK6A 4AXHA 5ACSA 4PVOA 4XWTA 3SBLA 5DPXA 3SRXA 4H0DA 4D1TA 4AWZA 2Y8BA 2BG7A 5EW0A 5IQKA 4B87A 2AIOA 1L9YA 2YNUA 1WW1A 4NQ2A 4NQ6A 2Y87A 3AF6A 2NXAA 3IEMA 2GFJA 5A87A 1JJTA 3JXPA 2ZZIA 4FR7A 3SW3A 2FHXA 1K07A 1SMLA 2I7TA 3ADRA 5A0TA 1QH3A 5ACQA 3X2XA 4Z7RA 2VW8A 4EXSA 2YCBA 3ESHA 4AD9A 1A8TA 1DDKA 4U4LA 3DHAA 3IE2A 4ZO3A 3T3OA 2DOOA 4YSBA 2BGAA 3ZQ4A 2ZWRA 1KO3A 2WHGA 5K4KA 2A7MA 2Y8AA 2H6AA 3I0VA 4RBSA 2BG8B 2QINA 4NURA 4XWWA 3R2UA 3DH8A 3RPCA 4TZBA 1WUOA 5AYAA 2M5DA 1X8IA 1X8HA 4UBQA 5HH5A 4AV7A 4EY2A 5EVDA 2BFKA 2CG3A 4HL2A 2QDTA 5EV8A 5B3RA 2QEDA 2GMNA 5HIQA 5K4MA 4ZO2A 3ZR9A 3SPUA 3I11A 3G1PA 1XM8A 3A4YA 4J5HA 1WRAA 3BC2A 5HIPA 4NQ4A 2GKLA 3H3EA 2YNTA 2E7YA 3FCZA 1BVTA 4AX0B 3SFPA 2DKFA 3I13A 4RAWA 4CHLA 2BR6A 2FU7A 1XTOA 2BIBA 1BMCA 3RKJA 3MD7A 2BG2A 5AJLA 2CFZA 1MQOA 1JT1A 1WUPA 3P2UA 5EV6A 5ACPA 5HH4A 4RL2A 4V0HA 5EWAA 4Z60A 2YNVB 5AXRA 2CFUA 4TZFA 3BK2A 4TYTA 4YSKA 4LE6A 2I7XA 5ACUA 1Y44A 3PY6A 2YHEA 5ACRA 3IDZA 2R2DA 1HLKA 4ZEJA 2WRSA 5FQCA 3DHCA 4AX1B 5HIOA 2NYPA 5LE1A 5EHTA 1JJEA 5A23A 5AXOA 4YSLA 2GFKA 3S0ZA 4F6ZA 3PG4A 4EXYA 5LSCA 4JO0A 5B1UA 2P97A 5AIJA 2ZNBA 1YCGA 2BC2A 1ZNBA 5LCFA 2YNWA 2P18A 4XUKA 1VMEA 2OHJA 2BG8A 3ZNBA 5ACVA 5EH9A 1YCHA 1E5DA 2XF4A 4KEQA 2XR1A 2FM6A 3T9MA 4C09A 1QH5A 3IE0A 3T3NA 1VGNA 4EFZA 4BZ3A 3KL7A 2Q0IA 4PDXA 2P1EA 3X30A 3IE1A 2CG2A 1X8GA 1YCFA 2QDSA 2ZO4A 2WYMA 2OHIA 5K4NA 4Z6XA 3LVZA 3I14A 1VJNA 4C1DA 5LS3A 3IELA 2BFZB 2I7VA 4C1HA 2P4ZA 5FQBA 2WYLA 1ZKPA 3DHBA 5LM6A 5A5ZA 2BG6A 4RM5A 3VPEA 5HH6A 3X2YA 5ACWA 4TZ9A 5LCHA 1KR3A 3QH8A 2BFZA 2FU9A 2FHXB 1DD6A 4Z67A 2AZ4A 5ACTA 4EYFA 4PVTA 2M5CA 2Q42A 5LLDA 3I15A 3PY5A 2BTNA 3SD9A 3IOGA 4DIKA 3L6NA
chains in the Genus database with same CATH topology
4NQ5A 4RL0A 2UYXA 5LCAA 4UWOB 2QJSA 2YZ3A 2YNVA 1A7TA 4TYFA 4EYBA 4P62A 4F6HA 5EVBA 3AF5A 4D1WA 1M2XA 4J5FA 2GCUA 4HKYA 4D02A 5AHRA 2OHHA 3BV6A 1BC2A 2BFLA 5B15A 2NZFA 5AEBA 4Z5ZA 3RKKA 1ZTCA 5KILA 4AWYB 2HB9A 4FEKA 4D1VA 5KIKA 2FU8A 1DXKA 4KEPA 3FAIA 2Q0JA 4GCWA 5A0VA 5EVKA 3F9OA 5LMCA 2WYMC 4DILA 3IEKA 4RAMA 4UWSB 2FU6A 4C1FA 5FQAA 5ACXA 4WD6A 4GYQA 3IOFA 4GYUA 4FSBA 4O98A 5K0WA 4Z5YA 3WXCA 4UAMA 3X2ZA 3TP9A 4UA4A 5HISA 2CBNA 4BP0A 2YNTB 4TZEA 3ZWFA 4C1CA 5AHOA 4C1GA 3KNSA 4UWRB 3BK1A 4C1EA 3Q6VA 1KO2A 3KNRA 4EYLA 2NZEA 4HL1A 4UWPB 3VQZA 2Q9UA 4ZNBA 3AJ3A 1P9EA 2BMIA 4D1UA 2FK6A 5ACSA 4PVOA 4XWTA 3SBLA 5DPXA 3SRXA 4H0DA 4D1TA 4AWZA 2Y8BA 2BG7A 5EW0A 5IQKA 4B87A 2AIOA 1L9YA 2YNUA 1WW1A 4NQ2A 4NQ6A 2Y87A 3AF6A 2NXAA 3IEMA 2GFJA 5A87A 1JJTA 3JXPA 2ZZIA 4FR7A 3SW3A 2FHXA 1K07A 1SMLA 2I7TA 3ADRA 5A0TA 1QH3A 5ACQA 3X2XA 4Z7RA 2VW8A 4EXSA 2YCBA 3ESHA 4AD9A 1A8TA 1DDKA 4U4LA 3DHAA 3IE2A 4ZO3A 3T3OA 2DOOA 4YSBA 2BGAA 3ZQ4A 2ZWRA 1KO3A 2WHGA 5K4KA 2A7MA 2Y8AA 2H6AA 3I0VA 4RBSA 2BG8B 2QINA 4XWWA 3R2UA 3DH8A 3RPCA 4TZBA 1WUOA 5AYAA 2M5DA 1X8IA 1X8HA 4UBQA 5HH5A 4EY2A 5EVDA 2BFKA 4HL2A 2QDTA 5EV8A 5B3RA 2QEDA 2GMNA 5HIQA 5K4MA 4ZO2A 3ZR9A 3SPUA 3I11A 3G1PA 1XM8A 3A4YA 4J5HA 1WRAA 3BC2A 5HIPA 4NQ4A 2GKLA 3H3EA 2YNTA 2E7YA 3FCZA 1BVTA 4AX0B 3SFPA 2DKFA 3I13A 4RAWA 4CHLA 2BR6A 2FU7A 1XTOA 2BIBA 1BMCA 3RKJA 3MD7A 2BG2A 1MQOA 1JT1A 1WUPA 3P2UA 5EV6A 5ACPA 5HH4A 4RL2A 4V0HA 5EWAA 4Z60A 2YNVB 5AXRA 4TZFA 3BK2A 4TYTA 4YSKA 4LE6A 2I7XA 5ACUA 1Y44A 3PY6A 5ACRA 3IDZA 2R2DA 1HLKA 4ZEJA 2WRSA 5FQCA 3DHCA 4AX1B 5HIOA 2NYPA 5LE1A 5EHTA 1JJEA 5AXOA 4YSLA 2GFKA 3S0ZA 4F6ZA 3PG4A 4EXYA 5LSCA 4JO0A 5B1UA 2P97A 2ZNBA 1YCGA 2BC2A 1ZNBA 5LCFA 2YNWA 2P18A 4XUKA 1VMEA 2OHJA 2BG8A 3ZNBA 5ACVA 5EH9A 1YCHA 1E5DA 2XF4A 4KEQA 2XR1A 2FM6A 3T9MA 4C09A 1QH5A 3IE0A 3T3NA 1VGNA 4EFZA 4BZ3A 3KL7A 2Q0IA 2P1EA 3X30A 3IE1A 1X8GA 1YCFA 2QDSA 2ZO4A 2WYMA 2OHIA 5K4NA 4Z6XA 3LVZA 3I14A 1VJNA 4C1DA 5LS3A 3IELA 2BFZB 2I7VA 4C1HA 2P4ZA 5FQBA 2WYLA 1ZKPA 3DHBA 5LM6A 5A5ZA 2BG6A 4RM5A 3VPEA 5HH6A 3X2YA 5ACWA 4TZ9A 5LCHA 1KR3A 3QH8A 2BFZA 2FU9A 2FHXB 1DD6A 4Z67A 2AZ4A 5ACTA 4EYFA 4PVTA 2M5CA 2Q42A 5LLDA 3I15A 3PY5A 2BTNA 3SD9A 3IOGA 4DIKA 3L6NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NQ5 A;  4RL0 A;  2UYX A;  5LCA A;  4UWO B;  2QJS A;  2YZ3 A;  2YNV A;  1A7T A;  4TYF A;  4EYB A;  4P62 A;  4F6H A;  5EVB A;  3AF5 A;  4D1W A;  1M2X A;  4J5F A;  2GCU A;  4HKY A;  4D02 A;  5AHR A;  2OHH A;  3BV6 A;  1BC2 A;  2BFL A;  5B15 A;  2NZF A;  5AEB A;  4Z5Z A;  3RKK A;  1ZTC A;  5KIL A;  4AWY B;  2HB9 A;  4FEK A;  4D1V A;  5KIK A;  2FU8 A;  1DXK A;  4KEP A;  3FAI A;  2Q0J A;  4GCW A;  5A0V A;  5EVK A;  3F9O A;  5LMC A;  2WYM C;  4DIL A;  3IEK A;  4RAM A;  4UWS B;  2FU6 A;  4C1F A;  5FQA A;  5ACX A;  4WD6 A;  4GYQ A;  3IOF A;  4GYU A;  4FSB A;  4O98 A;  5K0W A;  4Z5Y A;  3WXC A;  4UAM A;  3X2Z A;  3TP9 A;  4UA4 A;  5HIS A;  2CBN A;  4BP0 A;  2YNT B;  4TZE A;  3ZWF A;  4C1C A;  5AHO A;  4C1G A;  3KNS A;  4UWR B;  3BK1 A;  4C1E A;  3Q6V A;  1KO2 A;  3KNR A;  4EYL A;  2NZE A;  4HL1 A;  4UWP B;  3VQZ A;  2Q9U A;  4ZNB A;  3AJ3 A;  1P9E A;  2BMI A;  4D1U A;  2FK6 A;  5ACS A;  4PVO A;  4XWT A;  3SBL A;  5DPX A;  3SRX A;  4H0D A;  4D1T A;  4AWZ A;  2Y8B A;  2BG7 A;  5EW0 A;  5IQK A;  4B87 A;  2AIO A;  1L9Y A;  2YNU A;  1WW1 A;  4NQ2 A;  4NQ6 A;  2Y87 A;  3AF6 A;  2NXA A;  3IEM A;  2GFJ A;  5A87 A;  1JJT A;  3JXP A;  2ZZI A;  4FR7 A;  3SW3 A;  2FHX A;  1K07 A;  1SML A;  2I7T A;  3ADR A;  5A0T A;  1QH3 A;  5ACQ A;  3X2X A;  4Z7R A;  2VW8 A;  4EXS A;  2YCB A;  3ESH A;  4AD9 A;  1A8T A;  1DDK A;  4U4L A;  3DHA A;  3IE2 A;  4ZO3 A;  3T3O A;  2DOO A;  4YSB A;  2BGA A;  3ZQ4 A;  2ZWR A;  1KO3 A;  2WHG A;  5K4K A;  2A7M A;  2Y8A A;  2H6A A;  3I0V A;  4RBS A;  2BG8 B;  2QIN A;  4XWW A;  3R2U A;  3DH8 A;  3RPC A;  4TZB A;  1WUO A;  5AYA A;  2M5D A;  1X8I A;  1X8H A;  4UBQ A;  5HH5 A;  4EY2 A;  5EVD A;  2BFK A;  4HL2 A;  2QDT A;  5EV8 A;  5B3R A;  2QED A;  2GMN A;  5HIQ A;  5K4M A;  4ZO2 A;  3ZR9 A;  3SPU A;  3I11 A;  3G1P A;  1XM8 A;  3A4Y A;  4J5H A;  1WRA A;  3BC2 A;  5HIP A;  4NQ4 A;  2GKL A;  3H3E A;  2YNT A;  2E7Y A;  3FCZ A;  1BVT A;  4AX0 B;  3SFP A;  2DKF A;  3I13 A;  4RAW A;  4CHL A;  2BR6 A;  2FU7 A;  1XTO A;  2BIB A;  1BMC A;  3RKJ A;  3MD7 A;  2BG2 A;  1MQO A;  1JT1 A;  1WUP A;  3P2U A;  5EV6 A;  5ACP A;  5HH4 A;  4RL2 A;  4V0H A;  5EWA A;  4Z60 A;  2YNV B;  5AXR A;  4TZF A;  3BK2 A;  4TYT A;  4YSK A;  4LE6 A;  2I7X A;  5ACU A;  1Y44 A;  3PY6 A;  5ACR A;  3IDZ A;  2R2D A;  1HLK A;  4ZEJ A;  2WRS A;  5FQC A;  3DHC A;  4AX1 B;  5HIO A;  2NYP A;  5LE1 A;  5EHT A;  1JJE A;  5AXO A;  4YSL A;  2GFK A;  3S0Z A;  4F6Z A;  3PG4 A;  4EXY A;  5LSC A;  4JO0 A;  5B1U A;  2P97 A;  2ZNB A;  1YCG A;  2BC2 A;  1ZNB A;  5LCF A;  2YNW A;  2P18 A;  4XUK A;  1VME A;  2OHJ A;  2BG8 A;  3ZNB A;  5ACV A;  5EH9 A;  1YCH A;  1E5D A;  2XF4 A;  4KEQ A;  2XR1 A;  2FM6 A;  3T9M A;  4C09 A;  1QH5 A;  3IE0 A;  3T3N A;  1VGN A;  4EFZ A;  4BZ3 A;  3KL7 A;  2Q0I A;  2P1E A;  3X30 A;  3IE1 A;  1X8G A;  1YCF A;  2QDS A;  2ZO4 A;  2WYM A;  2OHI A;  5K4N A;  4Z6X A;  3LVZ A;  3I14 A;  1VJN A;  4C1D A;  5LS3 A;  3IEL A;  2BFZ B;  2I7V A;  4C1H A;  2P4Z A;  5FQB A;  2WYL A;  1ZKP A;  3DHB A;  5LM6 A;  5A5Z A;  2BG6 A;  4RM5 A;  3VPE A;  5HH6 A;  3X2Y A;  5ACW A;  4TZ9 A;  5LCH A;  1KR3 A;  3QH8 A;  2BFZ A;  2FU9 A;  2FHX B;  1DD6 A;  4Z67 A;  2AZ4 A;  5ACT A;  4EYF A;  4PVT A;  2M5C A;  2Q42 A;  5LLD A;  3I15 A;  3PY5 A;  2BTN A;  3SD9 A;  3IOG A;  4DIK A;  3L6N A; 
#chains in the Genus database with same CATH topology
 4NQ5 A;  4RL0 A;  2UYX A;  5LCA A;  4UWO B;  2QJS A;  2YZ3 A;  2YNV A;  1A7T A;  4TYF A;  4EYB A;  4P62 A;  4F6H A;  5EVB A;  3AF5 A;  4D1W A;  1M2X A;  4J5F A;  2GCU A;  4HKY A;  4D02 A;  5AHR A;  2OHH A;  3BV6 A;  1BC2 A;  2BFL A;  5B15 A;  2NZF A;  5AEB A;  4Z5Z A;  3RKK A;  1ZTC A;  5KIL A;  4AWY B;  2HB9 A;  4FEK A;  4D1V A;  5KIK A;  2FU8 A;  1DXK A;  4KEP A;  3FAI A;  2Q0J A;  4GCW A;  5A0V A;  5EVK A;  3F9O A;  5LMC A;  2WYM C;  4DIL A;  3IEK A;  4RAM A;  4UWS B;  2FU6 A;  4C1F A;  5FQA A;  5ACX A;  4WD6 A;  4GYQ A;  3IOF A;  4GYU A;  4FSB A;  4O98 A;  5K0W A;  4Z5Y A;  3WXC A;  4UAM A;  3X2Z A;  3TP9 A;  4UA4 A;  5HIS A;  2CBN A;  4BP0 A;  2YNT B;  4TZE A;  3ZWF A;  4C1C A;  5AHO A;  4C1G A;  3KNS A;  4UWR B;  3BK1 A;  4C1E A;  3Q6V A;  1KO2 A;  3KNR A;  4EYL A;  2NZE A;  4HL1 A;  4UWP B;  3VQZ A;  2Q9U A;  4ZNB A;  3AJ3 A;  1P9E A;  2BMI A;  4D1U A;  2FK6 A;  4AXH A;  5ACS A;  4PVO A;  4XWT A;  3SBL A;  5DPX A;  3SRX A;  4H0D A;  4D1T A;  4AWZ A;  2Y8B A;  2BG7 A;  5EW0 A;  5IQK A;  4B87 A;  2AIO A;  1L9Y A;  2YNU A;  1WW1 A;  4NQ2 A;  4NQ6 A;  2Y87 A;  3AF6 A;  2NXA A;  3IEM A;  2GFJ A;  5A87 A;  1JJT A;  3JXP A;  2ZZI A;  4FR7 A;  3SW3 A;  2FHX A;  1K07 A;  1SML A;  2I7T A;  3ADR A;  5A0T A;  1QH3 A;  5ACQ A;  3X2X A;  4Z7R A;  2VW8 A;  4EXS A;  2YCB A;  3ESH A;  4AD9 A;  1A8T A;  1DDK A;  4U4L A;  3DHA A;  3IE2 A;  4ZO3 A;  3T3O A;  2DOO A;  4YSB A;  2BGA A;  3ZQ4 A;  2ZWR A;  1KO3 A;  2WHG A;  5K4K A;  2A7M A;  2Y8A A;  2H6A A;  3I0V A;  4RBS A;  2BG8 B;  2QIN A;  4NUR A;  4XWW A;  3R2U A;  3DH8 A;  3RPC A;  4TZB A;  1WUO A;  5AYA A;  2M5D A;  1X8I A;  1X8H A;  4UBQ A;  5HH5 A;  4AV7 A;  4EY2 A;  5EVD A;  2BFK A;  2CG3 A;  4HL2 A;  2QDT A;  5EV8 A;  5B3R A;  2QED A;  2GMN A;  5HIQ A;  5K4M A;  4ZO2 A;  3ZR9 A;  3SPU A;  3I11 A;  3G1P A;  1XM8 A;  3A4Y A;  4J5H A;  1WRA A;  3BC2 A;  5HIP A;  4NQ4 A;  2GKL A;  3H3E A;  2YNT A;  2E7Y A;  3FCZ A;  1BVT A;  4AX0 B;  3SFP A;  2DKF A;  3I13 A;  4RAW A;  4CHL A;  2BR6 A;  2FU7 A;  1XTO A;  2BIB A;  1BMC A;  3RKJ A;  3MD7 A;  2BG2 A;  5AJL A;  2CFZ A;  1MQO A;  1JT1 A;  1WUP A;  3P2U A;  5EV6 A;  5ACP A;  5HH4 A;  4RL2 A;  4V0H A;  5EWA A;  4Z60 A;  2YNV B;  5AXR A;  2CFU A;  4TZF A;  3BK2 A;  4TYT A;  4YSK A;  4LE6 A;  2I7X A;  5ACU A;  1Y44 A;  3PY6 A;  2YHE A;  5ACR A;  3IDZ A;  2R2D A;  1HLK A;  4ZEJ A;  2WRS A;  5FQC A;  3DHC A;  4AX1 B;  5HIO A;  2NYP A;  5LE1 A;  5EHT A;  1JJE A;  5A23 A;  5AXO A;  4YSL A;  2GFK A;  3S0Z A;  4F6Z A;  3PG4 A;  4EXY A;  5LSC A;  4JO0 A;  5B1U A;  2P97 A;  5AIJ A;  2ZNB A;  1YCG A;  2BC2 A;  1ZNB A;  5LCF A;  2YNW A;  2P18 A;  4XUK A;  1VME A;  2OHJ A;  2BG8 A;  3ZNB A;  5ACV A;  5EH9 A;  1YCH A;  1E5D A;  2XF4 A;  4KEQ A;  2XR1 A;  2FM6 A;  3T9M A;  4C09 A;  1QH5 A;  3IE0 A;  3T3N A;  1VGN A;  4EFZ A;  4BZ3 A;  3KL7 A;  2Q0I A;  4PDX A;  2P1E A;  3X30 A;  3IE1 A;  2CG2 A;  1X8G A;  1YCF A;  2QDS A;  2ZO4 A;  2WYM A;  2OHI A;  5K4N A;  4Z6X A;  3LVZ A;  3I14 A;  1VJN A;  4C1D A;  5LS3 A;  3IEL A;  2BFZ B;  2I7V A;  4C1H A;  2P4Z A;  5FQB A;  2WYL A;  1ZKP A;  3DHB A;  5LM6 A;  5A5Z A;  2BG6 A;  4RM5 A;  3VPE A;  5HH6 A;  3X2Y A;  5ACW A;  4TZ9 A;  5LCH A;  1KR3 A;  3QH8 A;  2BFZ A;  2FU9 A;  2FHX B;  1DD6 A;  4Z67 A;  2AZ4 A;  5ACT A;  4EYF A;  4PVT A;  2M5C A;  2Q42 A;  5LLD A;  3I15 A;  3PY5 A;  2BTN A;  3SD9 A;  3IOG A;  4DIK A;  3L6N A; 
#chains in the Genus database with same CATH homology
 4NQ5 A;  4RL0 A;  2UYX A;  5LCA A;  4UWO B;  2QJS A;  2YZ3 A;  2YNV A;  1A7T A;  4TYF A;  4EYB A;  4P62 A;  4F6H A;  5EVB A;  3AF5 A;  4D1W A;  1M2X A;  4J5F A;  2GCU A;  4HKY A;  4D02 A;  5AHR A;  2OHH A;  3BV6 A;  1BC2 A;  2BFL A;  5B15 A;  2NZF A;  5AEB A;  4Z5Z A;  3RKK A;  1ZTC A;  5KIL A;  4AWY B;  2HB9 A;  4FEK A;  4D1V A;  5KIK A;  2FU8 A;  1DXK A;  4KEP A;  3FAI A;  2Q0J A;  4GCW A;  5A0V A;  5EVK A;  3F9O A;  5LMC A;  2WYM C;  4DIL A;  3IEK A;  4RAM A;  4UWS B;  2FU6 A;  4C1F A;  5FQA A;  5ACX A;  4WD6 A;  4GYQ A;  3IOF A;  4GYU A;  4FSB A;  4O98 A;  5K0W A;  4Z5Y A;  3WXC A;  4UAM A;  3X2Z A;  3TP9 A;  4UA4 A;  5HIS A;  2CBN A;  4BP0 A;  2YNT B;  4TZE A;  3ZWF A;  4C1C A;  5AHO A;  4C1G A;  3KNS A;  4UWR B;  3BK1 A;  4C1E A;  3Q6V A;  1KO2 A;  3KNR A;  4EYL A;  2NZE A;  4HL1 A;  4UWP B;  3VQZ A;  2Q9U A;  4ZNB A;  3AJ3 A;  1P9E A;  2BMI A;  4D1U A;  2FK6 A;  5ACS A;  4PVO A;  4XWT A;  3SBL A;  5DPX A;  3SRX A;  4H0D A;  4D1T A;  4AWZ A;  2Y8B A;  2BG7 A;  5EW0 A;  5IQK A;  4B87 A;  2AIO A;  1L9Y A;  2YNU A;  1WW1 A;  4NQ2 A;  4NQ6 A;  2Y87 A;  3AF6 A;  2NXA A;  3IEM A;  2GFJ A;  5A87 A;  1JJT A;  3JXP A;  2ZZI A;  4FR7 A;  3SW3 A;  2FHX A;  1K07 A;  1SML A;  2I7T A;  3ADR A;  5A0T A;  1QH3 A;  5ACQ A;  3X2X A;  4Z7R A;  2VW8 A;  4EXS A;  2YCB A;  3ESH A;  4AD9 A;  1A8T A;  1DDK A;  4U4L A;  3DHA A;  3IE2 A;  4ZO3 A;  3T3O A;  2DOO A;  4YSB A;  2BGA A;  3ZQ4 A;  2ZWR A;  1KO3 A;  2WHG A;  5K4K A;  2A7M A;  2Y8A A;  2H6A A;  3I0V A;  4RBS A;  2BG8 B;  2QIN A;  4XWW A;  3R2U A;  3DH8 A;  3RPC A;  4TZB A;  1WUO A;  5AYA A;  2M5D A;  1X8I A;  1X8H A;  4UBQ A;  5HH5 A;  4EY2 A;  5EVD A;  2BFK A;  4HL2 A;  2QDT A;  5EV8 A;  5B3R A;  2QED A;  2GMN A;  5HIQ A;  5K4M A;  4ZO2 A;  3ZR9 A;  3SPU A;  3I11 A;  3G1P A;  1XM8 A;  3A4Y A;  4J5H A;  1WRA A;  3BC2 A;  5HIP A;  4NQ4 A;  2GKL A;  3H3E A;  2YNT A;  2E7Y A;  3FCZ A;  1BVT A;  4AX0 B;  3SFP A;  2DKF A;  3I13 A;  4RAW A;  4CHL A;  2BR6 A;  2FU7 A;  1XTO A;  2BIB A;  1BMC A;  3RKJ A;  3MD7 A;  2BG2 A;  1MQO A;  1JT1 A;  1WUP A;  3P2U A;  5EV6 A;  5ACP A;  5HH4 A;  4RL2 A;  4V0H A;  5EWA A;  4Z60 A;  2YNV B;  5AXR A;  4TZF A;  3BK2 A;  4TYT A;  4YSK A;  4LE6 A;  2I7X A;  5ACU A;  1Y44 A;  3PY6 A;  5ACR A;  3IDZ A;  2R2D A;  1HLK A;  4ZEJ A;  2WRS A;  5FQC A;  3DHC A;  4AX1 B;  5HIO A;  2NYP A;  5LE1 A;  5EHT A;  1JJE A;  5AXO A;  4YSL A;  2GFK A;  3S0Z A;  4F6Z A;  3PG4 A;  4EXY A;  5LSC A;  4JO0 A;  5B1U A;  2P97 A;  2ZNB A;  1YCG A;  2BC2 A;  1ZNB A;  5LCF A;  2YNW A;  2P18 A;  4XUK A;  1VME A;  2OHJ A;  2BG8 A;  3ZNB A;  5ACV A;  5EH9 A;  1YCH A;  1E5D A;  2XF4 A;  4KEQ A;  2XR1 A;  2FM6 A;  3T9M A;  4C09 A;  1QH5 A;  3IE0 A;  3T3N A;  1VGN A;  4EFZ A;  4BZ3 A;  3KL7 A;  2Q0I A;  2P1E A;  3X30 A;  3IE1 A;  1X8G A;  1YCF A;  2QDS A;  2ZO4 A;  2WYM A;  2OHI A;  5K4N A;  4Z6X A;  3LVZ A;  3I14 A;  1VJN A;  4C1D A;  5LS3 A;  3IEL A;  2BFZ B;  2I7V A;  4C1H A;  2P4Z A;  5FQB A;  2WYL A;  1ZKP A;  3DHB A;  5LM6 A;  5A5Z A;  2BG6 A;  4RM5 A;  3VPE A;  5HH6 A;  3X2Y A;  5ACW A;  4TZ9 A;  5LCH A;  1KR3 A;  3QH8 A;  2BFZ A;  2FU9 A;  2FHX B;  1DD6 A;  4Z67 A;  2AZ4 A;  5ACT A;  4EYF A;  4PVT A;  2M5C A;  2Q42 A;  5LLD A;  3I15 A;  3PY5 A;  2BTN A;  3SD9 A;  3IOG A;  4DIK A;  3L6N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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