5ACWA

Vim-2-1, discovery of novel inhibitor scaffolds against the metallo- beta-lactamase vim-2 by spr based fragment screening
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
233
structure length
232
Chain Sequence
b'GEYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNRS'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords BETA-LACTAMASE
publication title Discovery of Novel Inhibitor Scaffolds Against the Metallo-Beta-Lactamase Vim-2 by Spr Based Fragment Screening
pubmed doi rcsb
source organism Pseudomonas aeruginosa
molecule tags Hydrolase
total genus 73
structure length 232
sequence length 233
chains with identical sequence B
ec nomenclature ec 3.5.2.6: Beta-lactamase.
pdb deposition date 2015-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5acwA00
4D1TA 5FQCA 5KIKA 1BVTA 3SD9A 3RKJA 3WXCA 1XTOA 4UWSB 2OHHA 4BP0A 4EFZA 5LS3A 4P62A 3IEMA 4TYTA 4WD6A 5AEBA 2GFKA 4HKYA 1L9YA 1DD6A 1JT1A 4GCWA 5K4MA 4F6ZA 4Z67A 5EVDA 2NXAA 3BC2A 4HL2A 2BFZB 3I14A 4Z5YA 1VGNA 2NZFA 5EV8A 5EW0A 3X2ZA 3ADRA 5K0WA 5IQKA 2YNTB 1HLKA 1E5DA 4UBQA 2XR1A 2FU9A 2FM6A 4EYLA 2BC2A 5ACQA 4TZ9A 1P9EA 4V0HA 4C1FA 1BMCA 2M5CA 5A0TA 1WRAA 3X30A 2I7VA 1WUOA 4NQ6A 2DKFA 4AD9A 2R2DA 1YCGA 4J5HA 2FU7A 5A5ZA 1X8IA 3IDZA 1KR3A 5ACRA 4FR7A 4XUKA 3SRXA 3KNRA 5AHRA 2BFLA 4C1DA 1A7TA 4TZEA 4UWPB 1A8TA 2GFJA 3T3OA 4D1UA 3KL7A 2BGAA 4HL1A 4DILA 3AF5A 4EXYA 2AIOA 2WHGA 4RAWA 1WUPA 4D02A 2ZZIA 5AHOA 1VJNA 3TP9A 1BC2A 4D1WA 5A0VA 3ZWFA 5LCAA 3F9OA 2BR6A 3RKKA 2BFZA 4H0DA 2GMNA 4Z6XA 3IE2A 4C1EA 3IE0A 4ZO3A 5ACPA 2Q0IA 1SMLA 2P18A 2YNTA 4RAMA 3L6NA 5HIQA 4FEKA 3S0ZA 5EH9A 2GKLA 5EVKA 4C1HA 3AF6A 3PY6A 2A7MA 4CHLA 3AJ3A 2FHXB 2Y8BA 2Q0JA 1DDKA 1YCFA 4J5FA 2WYLA 2WYMA 5LCHA 4GYUA 4KEQA 3IEKA 3PG4A 4YSLA 4EXSA 2BTNA 5ACWA 4UWRB 2YZ3A 3DHBA 5HH4A 4DIKA 4AWZA 2BG7A 4UWOB 1JJEA 4RM5A 2ZO4A 1MQOA 2OHJA 5HIPA 2ZWRA 1ZNBA 4TZFA 3I15A 5B3RA 2DOOA 3P2UA 1YCHA 2I7TA 3ZNBA 3VPEA 3G1PA 4O98A 2QDSA 5K4KA 4NQ4A 2BG6A 5EVBA 5HISA 3IOGA 3IOFA 3SW3A 1ZKPA 1K07A 3R2UA 3ZQ4A 3FCZA 3DH8A 3LVZA 5LLDA 2BG2A 3IELA 3VQZA 5HH5A 3T3NA 2E7YA 2YCBA 3JXPA 3ESHA 1QH5A 4C09A 3QH8A 4C1CA 4JO0A 1QH3A 5K4NA 2WRSA 4Z5ZA 2QEDA 5A87A 3I11A 2FHXA 3A4YA 5HH6A 2VW8A 2BMIA 4TZBA 4Z60A 2I7XA 1M2XA 3T9MA 3BK1A 3SFPA 2M5DA 2YNVB 3BK2A 1KO3A 3IE1A 4BZ3A 5EHTA 2BG8B 2XF4A 4GYQA 4YSBA 4B87A 5ACTA 1DXKA 4ZEJA 4NQ2A 3X2YA 4FSBA 2P97A 5ACSA 3ZR9A 5B15A 4EYBA 2BIBA 3I0VA 1JJTA 4PVOA 4NQ5A 3KNSA 3X2XA 2QJSA 5LM6A 4UA4A 4C1GA 4AX0B 4PVTA 4AX1B 4D1VA 4YSKA 2CBNA 4RBSA 2UYXA 2BFKA 5LMCA 2YNWA 4U4LA 1ZTCA 1KO2A 4XWWA 5ACXA 2OHIA 5LCFA 1XM8A 2FU8A 1Y44A 5AXRA 2Y87A 2QINA 2QDTA 5FQAA 2FK6A 2P1EA 5EV6A 2WYMC 1X8GA 2Y8AA 2YNUA 2GCUA 4KEPA 3RPCA 4AWYB 2NYPA 3MD7A 4ZO2A 5KILA 3SPUA 5ACVA 3PY5A 4LE6A 2YNVA 4RL0A 2ZNBA 5ACUA 5DPXA 5EWAA 2BG8A 4F6HA 4Z7RA 1VMEA 5B1UA 5HIOA 4EY2A 5AYAA 5AXOA 3BV6A 4RL2A 2Q42A 3DHAA 2H6AA 4XWTA 3SBLA 2AZ4A 4EYFA 2FU6A 2NZEA 4UAMA 2HB9A 3DHCA 5LE1A 1WW1A 5LSCA 2Q9UA 5FQBA 1X8HA 3H3EA 4ZNBA 3Q6VA 3I13A 4TYFA 2P4ZA 3FAIA
chains in the Genus database with same CATH superfamily
4D1TA 5FQCA 5KIKA 1BVTA 4PDXA 3SD9A 3RKJA 3WXCA 1XTOA 4UWSB 2CG2A 2OHHA 4BP0A 4EFZA 5LS3A 4P62A 3IEMA 4TYTA 4WD6A 5AEBA 2GFKA 4HKYA 1L9YA 1DD6A 1JT1A 4GCWA 5K4MA 4F6ZA 4Z67A 5EVDA 2NXAA 3BC2A 4HL2A 2BFZB 3I14A 4Z5YA 1VGNA 2NZFA 5EV8A 5EW0A 3X2ZA 3ADRA 5K0WA 5IQKA 2YNTB 1HLKA 1E5DA 4UBQA 2XR1A 2FU9A 2FM6A 4EYLA 2BC2A 5ACQA 4TZ9A 1P9EA 4V0HA 4C1FA 1BMCA 2M5CA 5A0TA 1WRAA 3X30A 2I7VA 1WUOA 4NQ6A 2DKFA 4AD9A 2R2DA 1YCGA 4J5HA 2YHEA 2FU7A 5A5ZA 1X8IA 3IDZA 1KR3A 5ACRA 4FR7A 4XUKA 3SRXA 3KNRA 5AHRA 2BFLA 2CG3A 4C1DA 1A7TA 4TZEA 4UWPB 1A8TA 2GFJA 3T3OA 4D1UA 3KL7A 2BGAA 4HL1A 4DILA 3AF5A 4EXYA 2AIOA 2WHGA 4RAWA 4NURA 1WUPA 4D02A 2ZZIA 5AHOA 1VJNA 3TP9A 1BC2A 4D1WA 5A0VA 3ZWFA 5LCAA 3F9OA 2BR6A 3RKKA 2BFZA 4H0DA 2GMNA 4Z6XA 3IE2A 4C1EA 3IE0A 4ZO3A 5ACPA 2Q0IA 1SMLA 2P18A 2YNTA 4RAMA 3L6NA 5HIQA 4FEKA 3S0ZA 5EH9A 2GKLA 5EVKA 4C1HA 3AF6A 2CFUA 3PY6A 2A7MA 4CHLA 3AJ3A 2FHXB 2Y8BA 2Q0JA 1DDKA 1YCFA 4J5FA 2WYLA 2WYMA 5LCHA 4GYUA 4KEQA 3IEKA 3PG4A 4YSLA 4EXSA 2BTNA 4AV7A 5ACWA 4UWRB 2YZ3A 3DHBA 5HH4A 4DIKA 4AWZA 2BG7A 4UWOB 1JJEA 4RM5A 2ZO4A 1MQOA 2OHJA 5HIPA 2ZWRA 1ZNBA 4TZFA 3I15A 5B3RA 2DOOA 3P2UA 1YCHA 4AXHA 2I7TA 3ZNBA 3VPEA 3G1PA 4O98A 2QDSA 5K4KA 4NQ4A 2BG6A 5EVBA 5HISA 3IOGA 3IOFA 3SW3A 1ZKPA 1K07A 3R2UA 3ZQ4A 3FCZA 3DH8A 3LVZA 5LLDA 2BG2A 3IELA 3VQZA 5HH5A 3T3NA 2E7YA 2YCBA 3JXPA 3ESHA 1QH5A 5A23A 4C09A 3QH8A 5AJLA 4C1CA 4JO0A 1QH3A 5K4NA 2WRSA 4Z5ZA 2QEDA 5A87A 3I11A 2FHXA 3A4YA 5HH6A 2VW8A 2BMIA 4TZBA 4Z60A 2I7XA 1M2XA 3T9MA 3BK1A 3SFPA 2M5DA 2YNVB 3BK2A 1KO3A 3IE1A 4BZ3A 5EHTA 2BG8B 2XF4A 4GYQA 4YSBA 4B87A 5ACTA 1DXKA 4ZEJA 4NQ2A 3X2YA 4FSBA 2P97A 5ACSA 3ZR9A 5B15A 4EYBA 2BIBA 3I0VA 1JJTA 4PVOA 4NQ5A 3KNSA 3X2XA 2QJSA 5LM6A 4UA4A 4C1GA 4AX0B 4PVTA 4AX1B 4D1VA 4YSKA 2CBNA 4RBSA 2UYXA 2BFKA 5LMCA 2YNWA 4U4LA 1ZTCA 1KO2A 4XWWA 5ACXA 2OHIA 5LCFA 1XM8A 2FU8A 1Y44A 5AXRA 2Y87A 2QINA 2QDTA 5FQAA 2FK6A 2P1EA 5EV6A 2WYMC 1X8GA 2Y8AA 2YNUA 2GCUA 4KEPA 3RPCA 4AWYB 2NYPA 2CFZA 5AIJA 3MD7A 4ZO2A 5KILA 3SPUA 5ACVA 3PY5A 4LE6A 2YNVA 4RL0A 2ZNBA 5ACUA 5DPXA 5EWAA 2BG8A 4F6HA 4Z7RA 1VMEA 5B1UA 5HIOA 4EY2A 5AYAA 5AXOA 3BV6A 4RL2A 2Q42A 3DHAA 2H6AA 4XWTA 3SBLA 2AZ4A 4EYFA 2FU6A 2NZEA 4UAMA 2HB9A 3DHCA 5LE1A 1WW1A 5LSCA 2Q9UA 5FQBA 1X8HA 3H3EA 4ZNBA 3Q6VA 3I13A 4TYFA 2P4ZA 3FAIA
chains in the Genus database with same CATH topology
4D1TA 5FQCA 5KIKA 1BVTA 3SD9A 3RKJA 3WXCA 1XTOA 4UWSB 2OHHA 4BP0A 4EFZA 5LS3A 4P62A 3IEMA 4TYTA 4WD6A 5AEBA 2GFKA 4HKYA 1L9YA 1DD6A 1JT1A 4GCWA 5K4MA 4F6ZA 4Z67A 5EVDA 2NXAA 3BC2A 4HL2A 2BFZB 3I14A 4Z5YA 1VGNA 2NZFA 5EV8A 5EW0A 3X2ZA 3ADRA 5K0WA 5IQKA 2YNTB 1HLKA 1E5DA 4UBQA 2XR1A 2FU9A 2FM6A 4EYLA 2BC2A 5ACQA 4TZ9A 1P9EA 4V0HA 4C1FA 1BMCA 2M5CA 5A0TA 1WRAA 3X30A 2I7VA 1WUOA 4NQ6A 2DKFA 4AD9A 2R2DA 1YCGA 4J5HA 2FU7A 5A5ZA 1X8IA 3IDZA 1KR3A 5ACRA 4FR7A 4XUKA 3SRXA 3KNRA 5AHRA 2BFLA 4C1DA 1A7TA 4TZEA 4UWPB 1A8TA 2GFJA 3T3OA 4D1UA 3KL7A 2BGAA 4HL1A 4DILA 3AF5A 4EXYA 2AIOA 2WHGA 4RAWA 1WUPA 4D02A 2ZZIA 5AHOA 1VJNA 3TP9A 1BC2A 4D1WA 5A0VA 3ZWFA 5LCAA 3F9OA 2BR6A 3RKKA 2BFZA 4H0DA 2GMNA 4Z6XA 3IE2A 4C1EA 3IE0A 4ZO3A 5ACPA 2Q0IA 1SMLA 2P18A 2YNTA 4RAMA 3L6NA 5HIQA 4FEKA 3S0ZA 5EH9A 2GKLA 5EVKA 4C1HA 3AF6A 3PY6A 2A7MA 4CHLA 3AJ3A 2FHXB 2Y8BA 2Q0JA 1DDKA 1YCFA 4J5FA 2WYLA 2WYMA 5LCHA 4GYUA 4KEQA 3IEKA 3PG4A 4YSLA 4EXSA 2BTNA 5ACWA 4UWRB 2YZ3A 3DHBA 5HH4A 4DIKA 4AWZA 2BG7A 4UWOB 1JJEA 4RM5A 2ZO4A 1MQOA 2OHJA 5HIPA 2ZWRA 1ZNBA 4TZFA 3I15A 5B3RA 2DOOA 3P2UA 1YCHA 2I7TA 3ZNBA 3VPEA 3G1PA 4O98A 2QDSA 5K4KA 4NQ4A 2BG6A 5EVBA 5HISA 3IOGA 3IOFA 3SW3A 1ZKPA 1K07A 3R2UA 3ZQ4A 3FCZA 3DH8A 3LVZA 5LLDA 2BG2A 3IELA 3VQZA 5HH5A 3T3NA 2E7YA 2YCBA 3JXPA 3ESHA 1QH5A 4C09A 3QH8A 4C1CA 4JO0A 1QH3A 5K4NA 2WRSA 4Z5ZA 2QEDA 5A87A 3I11A 2FHXA 3A4YA 5HH6A 2VW8A 2BMIA 4TZBA 4Z60A 2I7XA 1M2XA 3T9MA 3BK1A 3SFPA 2M5DA 2YNVB 3BK2A 1KO3A 3IE1A 4BZ3A 5EHTA 2BG8B 2XF4A 4GYQA 4YSBA 4B87A 5ACTA 1DXKA 4ZEJA 4NQ2A 3X2YA 4FSBA 2P97A 5ACSA 3ZR9A 5B15A 4EYBA 2BIBA 3I0VA 1JJTA 4PVOA 4NQ5A 3KNSA 3X2XA 2QJSA 5LM6A 4UA4A 4C1GA 4AX0B 4PVTA 4AX1B 4D1VA 4YSKA 2CBNA 4RBSA 2UYXA 2BFKA 5LMCA 2YNWA 4U4LA 1ZTCA 1KO2A 4XWWA 5ACXA 2OHIA 5LCFA 1XM8A 2FU8A 1Y44A 5AXRA 2Y87A 2QINA 2QDTA 5FQAA 2FK6A 2P1EA 5EV6A 2WYMC 1X8GA 2Y8AA 2YNUA 2GCUA 4KEPA 3RPCA 4AWYB 2NYPA 3MD7A 4ZO2A 5KILA 3SPUA 5ACVA 3PY5A 4LE6A 2YNVA 4RL0A 2ZNBA 5ACUA 5DPXA 5EWAA 2BG8A 4F6HA 4Z7RA 1VMEA 5B1UA 5HIOA 4EY2A 5AYAA 5AXOA 3BV6A 4RL2A 2Q42A 3DHAA 2H6AA 4XWTA 3SBLA 2AZ4A 4EYFA 2FU6A 2NZEA 4UAMA 2HB9A 3DHCA 5LE1A 1WW1A 5LSCA 2Q9UA 5FQBA 1X8HA 3H3EA 4ZNBA 3Q6VA 3I13A 4TYFA 2P4ZA 3FAIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4D1T A;  5FQC A;  5KIK A;  1BVT A;  3SD9 A;  3RKJ A;  3WXC A;  1XTO A;  4UWS B;  2OHH A;  4BP0 A;  4EFZ A;  5LS3 A;  4P62 A;  3IEM A;  4TYT A;  4WD6 A;  5AEB A;  2GFK A;  4HKY A;  1L9Y A;  1DD6 A;  1JT1 A;  4GCW A;  5K4M A;  4F6Z A;  4Z67 A;  5EVD A;  2NXA A;  3BC2 A;  4HL2 A;  2BFZ B;  3I14 A;  4Z5Y A;  1VGN A;  2NZF A;  5EV8 A;  5EW0 A;  3X2Z A;  3ADR A;  5K0W A;  5IQK A;  2YNT B;  1HLK A;  1E5D A;  4UBQ A;  2XR1 A;  2FU9 A;  2FM6 A;  4EYL A;  2BC2 A;  5ACQ A;  4TZ9 A;  1P9E A;  4V0H A;  4C1F A;  1BMC A;  2M5C A;  5A0T A;  1WRA A;  3X30 A;  2I7V A;  1WUO A;  4NQ6 A;  2DKF A;  4AD9 A;  2R2D A;  1YCG A;  4J5H A;  2FU7 A;  5A5Z A;  1X8I A;  3IDZ A;  1KR3 A;  5ACR A;  4FR7 A;  4XUK A;  3SRX A;  3KNR A;  5AHR A;  2BFL A;  4C1D A;  1A7T A;  4TZE A;  4UWP B;  1A8T A;  2GFJ A;  3T3O A;  4D1U A;  3KL7 A;  2BGA A;  4HL1 A;  4DIL A;  3AF5 A;  4EXY A;  2AIO A;  2WHG A;  4RAW A;  1WUP A;  4D02 A;  2ZZI A;  5AHO A;  1VJN A;  3TP9 A;  1BC2 A;  4D1W A;  5A0V A;  3ZWF A;  5LCA A;  3F9O A;  2BR6 A;  3RKK A;  2BFZ A;  4H0D A;  2GMN A;  4Z6X A;  3IE2 A;  4C1E A;  3IE0 A;  4ZO3 A;  5ACP A;  2Q0I A;  1SML A;  2P18 A;  2YNT A;  4RAM A;  3L6N A;  5HIQ A;  4FEK A;  3S0Z A;  5EH9 A;  2GKL A;  5EVK A;  4C1H A;  3AF6 A;  3PY6 A;  2A7M A;  4CHL A;  3AJ3 A;  2FHX B;  2Y8B A;  2Q0J A;  1DDK A;  1YCF A;  4J5F A;  2WYL A;  2WYM A;  5LCH A;  4GYU A;  4KEQ A;  3IEK A;  3PG4 A;  4YSL A;  4EXS A;  2BTN A;  5ACW A;  4UWR B;  2YZ3 A;  3DHB A;  5HH4 A;  4DIK A;  4AWZ A;  2BG7 A;  4UWO B;  1JJE A;  4RM5 A;  2ZO4 A;  1MQO A;  2OHJ A;  5HIP A;  2ZWR A;  1ZNB A;  4TZF A;  3I15 A;  5B3R A;  2DOO A;  3P2U A;  1YCH A;  2I7T A;  3ZNB A;  3VPE A;  3G1P A;  4O98 A;  2QDS A;  5K4K A;  4NQ4 A;  2BG6 A;  5EVB A;  5HIS A;  3IOG A;  3IOF A;  3SW3 A;  1ZKP A;  1K07 A;  3R2U A;  3ZQ4 A;  3FCZ A;  3DH8 A;  3LVZ A;  5LLD A;  2BG2 A;  3IEL A;  3VQZ A;  5HH5 A;  3T3N A;  2E7Y A;  2YCB A;  3JXP A;  3ESH A;  1QH5 A;  4C09 A;  3QH8 A;  4C1C A;  4JO0 A;  1QH3 A;  5K4N A;  2WRS A;  4Z5Z A;  2QED A;  5A87 A;  3I11 A;  2FHX A;  3A4Y A;  5HH6 A;  2VW8 A;  2BMI A;  4TZB A;  4Z60 A;  2I7X A;  1M2X A;  3T9M A;  3BK1 A;  3SFP A;  2M5D A;  2YNV B;  3BK2 A;  1KO3 A;  3IE1 A;  4BZ3 A;  5EHT A;  2BG8 B;  2XF4 A;  4GYQ A;  4YSB A;  4B87 A;  5ACT A;  1DXK A;  4ZEJ A;  4NQ2 A;  3X2Y A;  4FSB A;  2P97 A;  5ACS A;  3ZR9 A;  5B15 A;  4EYB A;  2BIB A;  3I0V A;  1JJT A;  4PVO A;  4NQ5 A;  3KNS A;  3X2X A;  2QJS A;  5LM6 A;  4UA4 A;  4C1G A;  4AX0 B;  4PVT A;  4AX1 B;  4D1V A;  4YSK A;  2CBN A;  4RBS A;  2UYX A;  2BFK A;  5LMC A;  2YNW A;  4U4L A;  1ZTC A;  1KO2 A;  4XWW A;  5ACX A;  2OHI A;  5LCF A;  1XM8 A;  2FU8 A;  1Y44 A;  5AXR A;  2Y87 A;  2QIN A;  2QDT A;  5FQA A;  2FK6 A;  2P1E A;  5EV6 A;  2WYM C;  1X8G A;  2Y8A A;  2YNU A;  2GCU A;  4KEP A;  3RPC A;  4AWY B;  2NYP A;  3MD7 A;  4ZO2 A;  5KIL A;  3SPU A;  5ACV A;  3PY5 A;  4LE6 A;  2YNV A;  4RL0 A;  2ZNB A;  5ACU A;  5DPX A;  5EWA A;  2BG8 A;  4F6H A;  4Z7R A;  1VME A;  5B1U A;  5HIO A;  4EY2 A;  5AYA A;  5AXO A;  3BV6 A;  4RL2 A;  2Q42 A;  3DHA A;  2H6A A;  4XWT A;  3SBL A;  2AZ4 A;  4EYF A;  2FU6 A;  2NZE A;  4UAM A;  2HB9 A;  3DHC A;  5LE1 A;  1WW1 A;  5LSC A;  2Q9U A;  5FQB A;  1X8H A;  3H3E A;  4ZNB A;  3Q6V A;  3I13 A;  4TYF A;  2P4Z A;  3FAI A; 
#chains in the Genus database with same CATH topology
 4D1T A;  5FQC A;  5KIK A;  1BVT A;  4PDX A;  3SD9 A;  3RKJ A;  3WXC A;  1XTO A;  4UWS B;  2CG2 A;  2OHH A;  4BP0 A;  4EFZ A;  5LS3 A;  4P62 A;  3IEM A;  4TYT A;  4WD6 A;  5AEB A;  2GFK A;  4HKY A;  1L9Y A;  1DD6 A;  1JT1 A;  4GCW A;  5K4M A;  4F6Z A;  4Z67 A;  5EVD A;  2NXA A;  3BC2 A;  4HL2 A;  2BFZ B;  3I14 A;  4Z5Y A;  1VGN A;  2NZF A;  5EV8 A;  5EW0 A;  3X2Z A;  3ADR A;  5K0W A;  5IQK A;  2YNT B;  1HLK A;  1E5D A;  4UBQ A;  2XR1 A;  2FU9 A;  2FM6 A;  4EYL A;  2BC2 A;  5ACQ A;  4TZ9 A;  1P9E A;  4V0H A;  4C1F A;  1BMC A;  2M5C A;  5A0T A;  1WRA A;  3X30 A;  2I7V A;  1WUO A;  4NQ6 A;  2DKF A;  4AD9 A;  2R2D A;  1YCG A;  4J5H A;  2YHE A;  2FU7 A;  5A5Z A;  1X8I A;  3IDZ A;  1KR3 A;  5ACR A;  4FR7 A;  4XUK A;  3SRX A;  3KNR A;  5AHR A;  2BFL A;  2CG3 A;  4C1D A;  1A7T A;  4TZE A;  4UWP B;  1A8T A;  2GFJ A;  3T3O A;  4D1U A;  3KL7 A;  2BGA A;  4HL1 A;  4DIL A;  3AF5 A;  4EXY A;  2AIO A;  2WHG A;  4RAW A;  4NUR A;  1WUP A;  4D02 A;  2ZZI A;  5AHO A;  1VJN A;  3TP9 A;  1BC2 A;  4D1W A;  5A0V A;  3ZWF A;  5LCA A;  3F9O A;  2BR6 A;  3RKK A;  2BFZ A;  4H0D A;  2GMN A;  4Z6X A;  3IE2 A;  4C1E A;  3IE0 A;  4ZO3 A;  5ACP A;  2Q0I A;  1SML A;  2P18 A;  2YNT A;  4RAM A;  3L6N A;  5HIQ A;  4FEK A;  3S0Z A;  5EH9 A;  2GKL A;  5EVK A;  4C1H A;  3AF6 A;  2CFU A;  3PY6 A;  2A7M A;  4CHL A;  3AJ3 A;  2FHX B;  2Y8B A;  2Q0J A;  1DDK A;  1YCF A;  4J5F A;  2WYL A;  2WYM A;  5LCH A;  4GYU A;  4KEQ A;  3IEK A;  3PG4 A;  4YSL A;  4EXS A;  2BTN A;  4AV7 A;  5ACW A;  4UWR B;  2YZ3 A;  3DHB A;  5HH4 A;  4DIK A;  4AWZ A;  2BG7 A;  4UWO B;  1JJE A;  4RM5 A;  2ZO4 A;  1MQO A;  2OHJ A;  5HIP A;  2ZWR A;  1ZNB A;  4TZF A;  3I15 A;  5B3R A;  2DOO A;  3P2U A;  1YCH A;  4AXH A;  2I7T A;  3ZNB A;  3VPE A;  3G1P A;  4O98 A;  2QDS A;  5K4K A;  4NQ4 A;  2BG6 A;  5EVB A;  5HIS A;  3IOG A;  3IOF A;  3SW3 A;  1ZKP A;  1K07 A;  3R2U A;  3ZQ4 A;  3FCZ A;  3DH8 A;  3LVZ A;  5LLD A;  2BG2 A;  3IEL A;  3VQZ A;  5HH5 A;  3T3N A;  2E7Y A;  2YCB A;  3JXP A;  3ESH A;  1QH5 A;  5A23 A;  4C09 A;  3QH8 A;  5AJL A;  4C1C A;  4JO0 A;  1QH3 A;  5K4N A;  2WRS A;  4Z5Z A;  2QED A;  5A87 A;  3I11 A;  2FHX A;  3A4Y A;  5HH6 A;  2VW8 A;  2BMI A;  4TZB A;  4Z60 A;  2I7X A;  1M2X A;  3T9M A;  3BK1 A;  3SFP A;  2M5D A;  2YNV B;  3BK2 A;  1KO3 A;  3IE1 A;  4BZ3 A;  5EHT A;  2BG8 B;  2XF4 A;  4GYQ A;  4YSB A;  4B87 A;  5ACT A;  1DXK A;  4ZEJ A;  4NQ2 A;  3X2Y A;  4FSB A;  2P97 A;  5ACS A;  3ZR9 A;  5B15 A;  4EYB A;  2BIB A;  3I0V A;  1JJT A;  4PVO A;  4NQ5 A;  3KNS A;  3X2X A;  2QJS A;  5LM6 A;  4UA4 A;  4C1G A;  4AX0 B;  4PVT A;  4AX1 B;  4D1V A;  4YSK A;  2CBN A;  4RBS A;  2UYX A;  2BFK A;  5LMC A;  2YNW A;  4U4L A;  1ZTC A;  1KO2 A;  4XWW A;  5ACX A;  2OHI A;  5LCF A;  1XM8 A;  2FU8 A;  1Y44 A;  5AXR A;  2Y87 A;  2QIN A;  2QDT A;  5FQA A;  2FK6 A;  2P1E A;  5EV6 A;  2WYM C;  1X8G A;  2Y8A A;  2YNU A;  2GCU A;  4KEP A;  3RPC A;  4AWY B;  2NYP A;  2CFZ A;  5AIJ A;  3MD7 A;  4ZO2 A;  5KIL A;  3SPU A;  5ACV A;  3PY5 A;  4LE6 A;  2YNV A;  4RL0 A;  2ZNB A;  5ACU A;  5DPX A;  5EWA A;  2BG8 A;  4F6H A;  4Z7R A;  1VME A;  5B1U A;  5HIO A;  4EY2 A;  5AYA A;  5AXO A;  3BV6 A;  4RL2 A;  2Q42 A;  3DHA A;  2H6A A;  4XWT A;  3SBL A;  2AZ4 A;  4EYF A;  2FU6 A;  2NZE A;  4UAM A;  2HB9 A;  3DHC A;  5LE1 A;  1WW1 A;  5LSC A;  2Q9U A;  5FQB A;  1X8H A;  3H3E A;  4ZNB A;  3Q6V A;  3I13 A;  4TYF A;  2P4Z A;  3FAI A; 
#chains in the Genus database with same CATH homology
 4D1T A;  5FQC A;  5KIK A;  1BVT A;  3SD9 A;  3RKJ A;  3WXC A;  1XTO A;  4UWS B;  2OHH A;  4BP0 A;  4EFZ A;  5LS3 A;  4P62 A;  3IEM A;  4TYT A;  4WD6 A;  5AEB A;  2GFK A;  4HKY A;  1L9Y A;  1DD6 A;  1JT1 A;  4GCW A;  5K4M A;  4F6Z A;  4Z67 A;  5EVD A;  2NXA A;  3BC2 A;  4HL2 A;  2BFZ B;  3I14 A;  4Z5Y A;  1VGN A;  2NZF A;  5EV8 A;  5EW0 A;  3X2Z A;  3ADR A;  5K0W A;  5IQK A;  2YNT B;  1HLK A;  1E5D A;  4UBQ A;  2XR1 A;  2FU9 A;  2FM6 A;  4EYL A;  2BC2 A;  5ACQ A;  4TZ9 A;  1P9E A;  4V0H A;  4C1F A;  1BMC A;  2M5C A;  5A0T A;  1WRA A;  3X30 A;  2I7V A;  1WUO A;  4NQ6 A;  2DKF A;  4AD9 A;  2R2D A;  1YCG A;  4J5H A;  2FU7 A;  5A5Z A;  1X8I A;  3IDZ A;  1KR3 A;  5ACR A;  4FR7 A;  4XUK A;  3SRX A;  3KNR A;  5AHR A;  2BFL A;  4C1D A;  1A7T A;  4TZE A;  4UWP B;  1A8T A;  2GFJ A;  3T3O A;  4D1U A;  3KL7 A;  2BGA A;  4HL1 A;  4DIL A;  3AF5 A;  4EXY A;  2AIO A;  2WHG A;  4RAW A;  1WUP A;  4D02 A;  2ZZI A;  5AHO A;  1VJN A;  3TP9 A;  1BC2 A;  4D1W A;  5A0V A;  3ZWF A;  5LCA A;  3F9O A;  2BR6 A;  3RKK A;  2BFZ A;  4H0D A;  2GMN A;  4Z6X A;  3IE2 A;  4C1E A;  3IE0 A;  4ZO3 A;  5ACP A;  2Q0I A;  1SML A;  2P18 A;  2YNT A;  4RAM A;  3L6N A;  5HIQ A;  4FEK A;  3S0Z A;  5EH9 A;  2GKL A;  5EVK A;  4C1H A;  3AF6 A;  3PY6 A;  2A7M A;  4CHL A;  3AJ3 A;  2FHX B;  2Y8B A;  2Q0J A;  1DDK A;  1YCF A;  4J5F A;  2WYL A;  2WYM A;  5LCH A;  4GYU A;  4KEQ A;  3IEK A;  3PG4 A;  4YSL A;  4EXS A;  2BTN A;  5ACW A;  4UWR B;  2YZ3 A;  3DHB A;  5HH4 A;  4DIK A;  4AWZ A;  2BG7 A;  4UWO B;  1JJE A;  4RM5 A;  2ZO4 A;  1MQO A;  2OHJ A;  5HIP A;  2ZWR A;  1ZNB A;  4TZF A;  3I15 A;  5B3R A;  2DOO A;  3P2U A;  1YCH A;  2I7T A;  3ZNB A;  3VPE A;  3G1P A;  4O98 A;  2QDS A;  5K4K A;  4NQ4 A;  2BG6 A;  5EVB A;  5HIS A;  3IOG A;  3IOF A;  3SW3 A;  1ZKP A;  1K07 A;  3R2U A;  3ZQ4 A;  3FCZ A;  3DH8 A;  3LVZ A;  5LLD A;  2BG2 A;  3IEL A;  3VQZ A;  5HH5 A;  3T3N A;  2E7Y A;  2YCB A;  3JXP A;  3ESH A;  1QH5 A;  4C09 A;  3QH8 A;  4C1C A;  4JO0 A;  1QH3 A;  5K4N A;  2WRS A;  4Z5Z A;  2QED A;  5A87 A;  3I11 A;  2FHX A;  3A4Y A;  5HH6 A;  2VW8 A;  2BMI A;  4TZB A;  4Z60 A;  2I7X A;  1M2X A;  3T9M A;  3BK1 A;  3SFP A;  2M5D A;  2YNV B;  3BK2 A;  1KO3 A;  3IE1 A;  4BZ3 A;  5EHT A;  2BG8 B;  2XF4 A;  4GYQ A;  4YSB A;  4B87 A;  5ACT A;  1DXK A;  4ZEJ A;  4NQ2 A;  3X2Y A;  4FSB A;  2P97 A;  5ACS A;  3ZR9 A;  5B15 A;  4EYB A;  2BIB A;  3I0V A;  1JJT A;  4PVO A;  4NQ5 A;  3KNS A;  3X2X A;  2QJS A;  5LM6 A;  4UA4 A;  4C1G A;  4AX0 B;  4PVT A;  4AX1 B;  4D1V A;  4YSK A;  2CBN A;  4RBS A;  2UYX A;  2BFK A;  5LMC A;  2YNW A;  4U4L A;  1ZTC A;  1KO2 A;  4XWW A;  5ACX A;  2OHI A;  5LCF A;  1XM8 A;  2FU8 A;  1Y44 A;  5AXR A;  2Y87 A;  2QIN A;  2QDT A;  5FQA A;  2FK6 A;  2P1E A;  5EV6 A;  2WYM C;  1X8G A;  2Y8A A;  2YNU A;  2GCU A;  4KEP A;  3RPC A;  4AWY B;  2NYP A;  3MD7 A;  4ZO2 A;  5KIL A;  3SPU A;  5ACV A;  3PY5 A;  4LE6 A;  2YNV A;  4RL0 A;  2ZNB A;  5ACU A;  5DPX A;  5EWA A;  2BG8 A;  4F6H A;  4Z7R A;  1VME A;  5B1U A;  5HIO A;  4EY2 A;  5AYA A;  5AXO A;  3BV6 A;  4RL2 A;  2Q42 A;  3DHA A;  2H6A A;  4XWT A;  3SBL A;  2AZ4 A;  4EYF A;  2FU6 A;  2NZE A;  4UAM A;  2HB9 A;  3DHC A;  5LE1 A;  1WW1 A;  5LSC A;  2Q9U A;  5FQB A;  1X8H A;  3H3E A;  4ZNB A;  3Q6V A;  3I13 A;  4TYF A;  2P4Z A;  3FAI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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