5ACXA

Vim-2-2, discovery of novel inhibitor scaffolds against the metallo- beta-lactamase vim-2 by spr based fragment screening
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
233
structure length
231
Chain Sequence
GEYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGAIYELSTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNRS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords BETA-LACTAMASE
publication title Discovery of Novel Inhibitor Scaffolds Against the Metallo-Beta-Lactamase Vim-2 by Spr Based Fragment Screening
pubmed doi rcsb
source organism Pseudomonas aeruginosa
total genus 77
structure length 231
sequence length 233
chains with identical sequence B
ec nomenclature ec 3.5.2.6: Beta-lactamase.
pdb deposition date 2015-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5acxA00
2OHIA 2QINA 2BG7A 2GKLA 4ZO2A 2VW8A 3T9MA 4J5FA 4C1DA 4NQ4A 3SFPA 2BG6A 3ESHA 4C1FA 3PG4A 2YCBA 5EV6A 5K0WA 4JO0A 1X8GA 4AX0B 3PY5A 1VGNA 5LCFA 3TP9A 3X2ZA 4D1WA 4UWSB 4EYBA 4EXYA 5AHOA 2P1EA 3WXCA 2E7YA 1A7TA 5ACQA 4YSLA 3IE2A 2FU8A 2FU7A 5EVDA 4BZ3A 4D1UA 5FQBA 1DXKA 3DHBA 4B87A 5HIOA 2I7TA 1BC2A 4LE6A 4RL0A 3DHAA 4ZEJA 5ACTA 4FSBA 4V0HA 5AYAA 3VQZA 5AXRA 4NQ6A 1MQOA 4RAMA 4FR7A 2NXAA 1DDKA 3BK1A 4BP0A 2NZFA 2YNVA 5A5ZA 4GYUA 2FM6A 5ACPA 2OHJA 3FCZA 4YSBA 5LE1A 3T3NA 4RM5A 1JT1A 2Y8BA 4TZFA 5IQKA 1X8HA 2BFZB 3AF6A 2BTNA 3AJ3A 5ACUA 4Z6XA 3A4YA 3KNRA 4UWPB 5DPXA 1YCHA 2QEDA 1WRAA 1M2XA 1WUPA 1ZKPA 2ZO4A 3L6NA 1YCGA 4GYQA 4HL1A 4EYLA 5HIQA 1VMEA 2A7MA 5ACXA 1L9YA 2YZ3A 3RKJA 2ZNBA 2GMNA 5EH9A 4UBQA 2QJSA 1Y44A 2BFLA 4UWOB 3SRXA 3I14A 5HH4A 2YNUA 4YSKA 4U4LA 3I0VA 4NQ5A 2BGAA 5AXOA 2WYMC 1XM8A 2CBNA 5LLDA 3LVZA 3FAIA 1DD6A 5LSCA 3T3OA 5HH6A 3SPUA 1QH3A 2WYMA 2Q42A 2XF4A 3DHCA 2BMIA 5LMCA 2BG2A 4UA4A 2BR6A 1A8TA 3IOFA 3Q6VA 5FQAA 3X30A 4DILA 5EHTA 5B1UA 2FK6A 4HKYA 1P9EA 4HL2A 4XWWA 3IE0A 4GCWA 5KILA 2QDSA 4RL2A 1YCFA 5K4MA 2P97A 3BK2A 4EFZA 4D1VA 4CHLA 4DIKA 2Y8AA 4ZNBA 5EW0A 3IE1A 2FU9A 2BFZA 4TZ9A 1WUOA 2Q0JA 3KL7A 4NQ2A 2WYLA 5LS3A 5AHRA 1X8IA 4Z7RA 2ZZIA 3IEMA 2FHXB 5A87A 4TZEA 2Y87A 2NYPA 4C1GA 3MD7A 4FEKA 3ZNBA 3I15A 4Z67A 3G1PA 4H0DA 3R2UA 2NZEA 2YNTB 2ZWRA 4Z5YA 2H6AA 1HLKA 1ZTCA 3PY6A 5K4KA 4O98A 4AWZA 2I7XA 3H3EA 1KO3A 3SW3A 4C1HA 4PVOA 1VJNA 2AZ4A 2BG8B 5AEBA 2WRSA 5ACVA 1JJTA 3RKKA 2FU6A 5HISA 4C1CA 2GCUA 3I13A 3X2YA 4AWYB 1KO2A 4C09A 4C1EA 5B15A 5LM6A 2BC2A 3ZWFA 1SMLA 2HB9A 2YNWA 3SD9A 1XTOA 5KIKA 3IEKA 5EVKA 2OHHA 4KEPA 4RAWA 4Z5ZA 3BV6A 3P2UA 2BIBA 3ZQ4A 4J5HA 4TZBA 4KEQA 2M5DA 2DOOA 4XUKA 4XWTA 1WW1A 5EV8A 4TYFA 3I11A 3KNSA 4ZO3A 4EY2A 5FQCA 3SBLA 1KR3A 2GFJA 2P4ZA 5HIPA 3QH8A 4EYFA 2FHXA 2P18A 3ZR9A 5LCHA 1JJEA 5LCAA 4D1TA 2UYXA 3IDZA 1BVTA 3DH8A 3RPCA 1BMCA 4AD9A 2YNTA 5K4NA 2I7VA 4D02A 4RBSA 4WD6A 5HH5A 3F9OA 5ACRA 5A0TA 3S0ZA 1K07A 4TYTA 2M5CA 2QDTA 2R2DA 2AIOA 1E5DA 5ACSA 5ACWA 2BG8A 3AF5A 4PVTA 3VPEA 2GFKA 2WHGA 5A0VA 4F6HA 3JXPA 4AX1B 3IOGA 4UWRB 2DKFA 2Q9UA 4UAMA 2YNVB 1QH5A 2Q0IA 4EXSA 5B3RA 4F6ZA 4Z60A 3BC2A 1ZNBA 5EVBA 3IELA 2BFKA 2XR1A 5EWAA 3X2XA 4P62A 3ADRA
chains in the Genus database with same CATH superfamily
2OHIA 2QINA 2BG7A 2GKLA 4ZO2A 2VW8A 3T9MA 4J5FA 4C1DA 4NQ4A 3SFPA 2BG6A 3ESHA 4C1FA 3PG4A 2YCBA 5EV6A 5K0WA 4JO0A 1X8GA 4AX0B 3PY5A 1VGNA 5LCFA 3TP9A 3X2ZA 4D1WA 4UWSB 4EYBA 4EXYA 5AHOA 2P1EA 3WXCA 2E7YA 1A7TA 5ACQA 4YSLA 3IE2A 2FU8A 2FU7A 5EVDA 4BZ3A 4D1UA 5FQBA 1DXKA 3DHBA 4B87A 5HIOA 2I7TA 1BC2A 4LE6A 4RL0A 3DHAA 4ZEJA 5ACTA 4FSBA 4V0HA 5AYAA 3VQZA 5AXRA 4NQ6A 1MQOA 4RAMA 4FR7A 2NXAA 1DDKA 3BK1A 4BP0A 2NZFA 2YNVA 5A5ZA 4GYUA 2FM6A 5ACPA 2OHJA 3FCZA 2YHEA 4YSBA 5LE1A 3T3NA 4RM5A 1JT1A 5A23A 2Y8BA 4TZFA 5IQKA 1X8HA 2BFZB 3AF6A 2BTNA 3AJ3A 5ACUA 4Z6XA 3A4YA 3KNRA 4UWPB 5DPXA 1YCHA 2QEDA 1WRAA 2CG2A 1M2XA 1WUPA 1ZKPA 2ZO4A 2CG3A 3L6NA 1YCGA 4GYQA 4HL1A 4EYLA 5HIQA 1VMEA 2A7MA 5ACXA 1L9YA 2CFUA 2YZ3A 4AV7A 3RKJA 2ZNBA 2GMNA 5EH9A 4UBQA 2QJSA 1Y44A 2BFLA 4UWOB 3SRXA 3I14A 5HH4A 2YNUA 4YSKA 4U4LA 3I0VA 4NQ5A 2BGAA 2CFZA 5AXOA 2WYMC 1XM8A 2CBNA 5LLDA 3LVZA 3FAIA 1DD6A 5LSCA 3T3OA 5HH6A 3SPUA 1QH3A 2WYMA 2Q42A 2XF4A 3DHCA 2BMIA 5LMCA 2BG2A 4UA4A 2BR6A 1A8TA 3IOFA 3Q6VA 5FQAA 3X30A 4DILA 5EHTA 5B1UA 2FK6A 4HKYA 1P9EA 4HL2A 4XWWA 3IE0A 4GCWA 5KILA 2QDSA 4RL2A 1YCFA 5K4MA 2P97A 3BK2A 4EFZA 4D1VA 4CHLA 4DIKA 2Y8AA 4ZNBA 5EW0A 4PDXA 3IE1A 2FU9A 2BFZA 4TZ9A 1WUOA 2Q0JA 3KL7A 4NQ2A 2WYLA 5LS3A 5AHRA 1X8IA 4Z7RA 2ZZIA 3IEMA 2FHXB 5A87A 4TZEA 2Y87A 2NYPA 4C1GA 3MD7A 4FEKA 3ZNBA 3I15A 4Z67A 3G1PA 4H0DA 3R2UA 2NZEA 2YNTB 2ZWRA 4Z5YA 2H6AA 1HLKA 1ZTCA 3PY6A 5K4KA 4O98A 4AWZA 2I7XA 3H3EA 1KO3A 3SW3A 4C1HA 4PVOA 1VJNA 2AZ4A 2BG8B 5AEBA 2WRSA 5ACVA 1JJTA 3RKKA 2FU6A 5HISA 4C1CA 2GCUA 3I13A 3X2YA 4AWYB 1KO2A 4C09A 4C1EA 5B15A 5LM6A 2BC2A 3ZWFA 1SMLA 2HB9A 2YNWA 3SD9A 5AJLA 1XTOA 5KIKA 3IEKA 5EVKA 2OHHA 4KEPA 4RAWA 4Z5ZA 3BV6A 3P2UA 2BIBA 3ZQ4A 4J5HA 4TZBA 4KEQA 2M5DA 2DOOA 4XUKA 4XWTA 1WW1A 5EV8A 4TYFA 3I11A 3KNSA 4ZO3A 4EY2A 5FQCA 5AIJA 4NURA 3SBLA 1KR3A 2GFJA 2P4ZA 5HIPA 3QH8A 4EYFA 2FHXA 2P18A 3ZR9A 5LCHA 1JJEA 5LCAA 4D1TA 2UYXA 3IDZA 1BVTA 3DH8A 3RPCA 1BMCA 4AD9A 2YNTA 5K4NA 2I7VA 4D02A 4RBSA 4WD6A 4AXHA 5HH5A 3F9OA 5ACRA 5A0TA 3S0ZA 1K07A 4TYTA 2M5CA 2QDTA 2R2DA 2AIOA 1E5DA 5ACSA 5ACWA 2BG8A 3AF5A 4PVTA 3VPEA 2GFKA 2WHGA 5A0VA 4F6HA 3JXPA 4AX1B 3IOGA 4UWRB 2DKFA 2Q9UA 4UAMA 2YNVB 1QH5A 2Q0IA 4EXSA 5B3RA 4F6ZA 4Z60A 3BC2A 1ZNBA 5EVBA 3IELA 2BFKA 2XR1A 5EWAA 3X2XA 4P62A 3ADRA
chains in the Genus database with same CATH topology
2OHIA 2QINA 2BG7A 2GKLA 4ZO2A 2VW8A 3T9MA 4J5FA 4C1DA 4NQ4A 3SFPA 2BG6A 3ESHA 4C1FA 3PG4A 2YCBA 5EV6A 5K0WA 4JO0A 1X8GA 4AX0B 3PY5A 1VGNA 5LCFA 3TP9A 3X2ZA 4D1WA 4UWSB 4EYBA 4EXYA 5AHOA 2P1EA 3WXCA 2E7YA 1A7TA 5ACQA 4YSLA 3IE2A 2FU8A 2FU7A 5EVDA 4BZ3A 4D1UA 5FQBA 1DXKA 3DHBA 4B87A 5HIOA 2I7TA 1BC2A 4LE6A 4RL0A 3DHAA 4ZEJA 5ACTA 4FSBA 4V0HA 5AYAA 3VQZA 5AXRA 4NQ6A 1MQOA 4RAMA 4FR7A 2NXAA 1DDKA 3BK1A 4BP0A 2NZFA 2YNVA 5A5ZA 4GYUA 2FM6A 5ACPA 2OHJA 3FCZA 4YSBA 5LE1A 3T3NA 4RM5A 1JT1A 2Y8BA 4TZFA 5IQKA 1X8HA 2BFZB 3AF6A 2BTNA 3AJ3A 5ACUA 4Z6XA 3A4YA 3KNRA 4UWPB 5DPXA 1YCHA 2QEDA 1WRAA 1M2XA 1WUPA 1ZKPA 2ZO4A 3L6NA 1YCGA 4GYQA 4HL1A 4EYLA 5HIQA 1VMEA 2A7MA 5ACXA 1L9YA 2YZ3A 3RKJA 2ZNBA 2GMNA 5EH9A 4UBQA 2QJSA 1Y44A 2BFLA 4UWOB 3SRXA 3I14A 5HH4A 2YNUA 4YSKA 4U4LA 3I0VA 4NQ5A 2BGAA 5AXOA 2WYMC 1XM8A 2CBNA 5LLDA 3LVZA 3FAIA 1DD6A 5LSCA 3T3OA 5HH6A 3SPUA 1QH3A 2WYMA 2Q42A 2XF4A 3DHCA 2BMIA 5LMCA 2BG2A 4UA4A 2BR6A 1A8TA 3IOFA 3Q6VA 5FQAA 3X30A 4DILA 5EHTA 5B1UA 2FK6A 4HKYA 1P9EA 4HL2A 4XWWA 3IE0A 4GCWA 5KILA 2QDSA 4RL2A 1YCFA 5K4MA 2P97A 3BK2A 4EFZA 4D1VA 4CHLA 4DIKA 2Y8AA 4ZNBA 5EW0A 3IE1A 2FU9A 2BFZA 4TZ9A 1WUOA 2Q0JA 3KL7A 4NQ2A 2WYLA 5LS3A 5AHRA 1X8IA 4Z7RA 2ZZIA 3IEMA 2FHXB 5A87A 4TZEA 2Y87A 2NYPA 4C1GA 3MD7A 4FEKA 3ZNBA 3I15A 4Z67A 3G1PA 4H0DA 3R2UA 2NZEA 2YNTB 2ZWRA 4Z5YA 2H6AA 1HLKA 1ZTCA 3PY6A 5K4KA 4O98A 4AWZA 2I7XA 3H3EA 1KO3A 3SW3A 4C1HA 4PVOA 1VJNA 2AZ4A 2BG8B 5AEBA 2WRSA 5ACVA 1JJTA 3RKKA 2FU6A 5HISA 4C1CA 2GCUA 3I13A 3X2YA 4AWYB 1KO2A 4C09A 4C1EA 5B15A 5LM6A 2BC2A 3ZWFA 1SMLA 2HB9A 2YNWA 3SD9A 1XTOA 5KIKA 3IEKA 5EVKA 2OHHA 4KEPA 4RAWA 4Z5ZA 3BV6A 3P2UA 2BIBA 3ZQ4A 4J5HA 4TZBA 4KEQA 2M5DA 2DOOA 4XUKA 4XWTA 1WW1A 5EV8A 4TYFA 3I11A 3KNSA 4ZO3A 4EY2A 5FQCA 3SBLA 1KR3A 2GFJA 2P4ZA 5HIPA 3QH8A 4EYFA 2FHXA 2P18A 3ZR9A 5LCHA 1JJEA 5LCAA 4D1TA 2UYXA 3IDZA 1BVTA 3DH8A 3RPCA 1BMCA 4AD9A 2YNTA 5K4NA 2I7VA 4D02A 4RBSA 4WD6A 5HH5A 3F9OA 5ACRA 5A0TA 3S0ZA 1K07A 4TYTA 2M5CA 2QDTA 2R2DA 2AIOA 1E5DA 5ACSA 5ACWA 2BG8A 3AF5A 4PVTA 3VPEA 2GFKA 2WHGA 5A0VA 4F6HA 3JXPA 4AX1B 3IOGA 4UWRB 2DKFA 2Q9UA 4UAMA 2YNVB 1QH5A 2Q0IA 4EXSA 5B3RA 4F6ZA 4Z60A 3BC2A 1ZNBA 5EVBA 3IELA 2BFKA 2XR1A 5EWAA 3X2XA 4P62A 3ADRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OHI A;  2QIN A;  2BG7 A;  2GKL A;  4ZO2 A;  2VW8 A;  3T9M A;  4J5F A;  4C1D A;  4NQ4 A;  3SFP A;  2BG6 A;  3ESH A;  4C1F A;  3PG4 A;  2YCB A;  5EV6 A;  5K0W A;  4JO0 A;  1X8G A;  4AX0 B;  3PY5 A;  1VGN A;  5LCF A;  3TP9 A;  3X2Z A;  4D1W A;  4UWS B;  4EYB A;  4EXY A;  5AHO A;  2P1E A;  3WXC A;  2E7Y A;  1A7T A;  5ACQ A;  4YSL A;  3IE2 A;  2FU8 A;  2FU7 A;  5EVD A;  4BZ3 A;  4D1U A;  5FQB A;  1DXK A;  3DHB A;  4B87 A;  5HIO A;  2I7T A;  1BC2 A;  4LE6 A;  4RL0 A;  3DHA A;  4ZEJ A;  5ACT A;  4FSB A;  4V0H A;  5AYA A;  3VQZ A;  5AXR A;  4NQ6 A;  1MQO A;  4RAM A;  4FR7 A;  2NXA A;  1DDK A;  3BK1 A;  4BP0 A;  2NZF A;  2YNV A;  5A5Z A;  4GYU A;  2FM6 A;  5ACP A;  2OHJ A;  3FCZ A;  4YSB A;  5LE1 A;  3T3N A;  4RM5 A;  1JT1 A;  2Y8B A;  4TZF A;  5IQK A;  1X8H A;  2BFZ B;  3AF6 A;  2BTN A;  3AJ3 A;  5ACU A;  4Z6X A;  3A4Y A;  3KNR A;  4UWP B;  5DPX A;  1YCH A;  2QED A;  1WRA A;  1M2X A;  1WUP A;  1ZKP A;  2ZO4 A;  3L6N A;  1YCG A;  4GYQ A;  4HL1 A;  4EYL A;  5HIQ A;  1VME A;  2A7M A;  5ACX A;  1L9Y A;  2YZ3 A;  3RKJ A;  2ZNB A;  2GMN A;  5EH9 A;  4UBQ A;  2QJS A;  1Y44 A;  2BFL A;  4UWO B;  3SRX A;  3I14 A;  5HH4 A;  2YNU A;  4YSK A;  4U4L A;  3I0V A;  4NQ5 A;  2BGA A;  5AXO A;  2WYM C;  1XM8 A;  2CBN A;  5LLD A;  3LVZ A;  3FAI A;  1DD6 A;  5LSC A;  3T3O A;  5HH6 A;  3SPU A;  1QH3 A;  2WYM A;  2Q42 A;  2XF4 A;  3DHC A;  2BMI A;  5LMC A;  2BG2 A;  4UA4 A;  2BR6 A;  1A8T A;  3IOF A;  3Q6V A;  5FQA A;  3X30 A;  4DIL A;  5EHT A;  5B1U A;  2FK6 A;  4HKY A;  1P9E A;  4HL2 A;  4XWW A;  3IE0 A;  4GCW A;  5KIL A;  2QDS A;  4RL2 A;  1YCF A;  5K4M A;  2P97 A;  3BK2 A;  4EFZ A;  4D1V A;  4CHL A;  4DIK A;  2Y8A A;  4ZNB A;  5EW0 A;  3IE1 A;  2FU9 A;  2BFZ A;  4TZ9 A;  1WUO A;  2Q0J A;  3KL7 A;  4NQ2 A;  2WYL A;  5LS3 A;  5AHR A;  1X8I A;  4Z7R A;  2ZZI A;  3IEM A;  2FHX B;  5A87 A;  4TZE A;  2Y87 A;  2NYP A;  4C1G A;  3MD7 A;  4FEK A;  3ZNB A;  3I15 A;  4Z67 A;  3G1P A;  4H0D A;  3R2U A;  2NZE A;  2YNT B;  2ZWR A;  4Z5Y A;  2H6A A;  1HLK A;  1ZTC A;  3PY6 A;  5K4K A;  4O98 A;  4AWZ A;  2I7X A;  3H3E A;  1KO3 A;  3SW3 A;  4C1H A;  4PVO A;  1VJN A;  2AZ4 A;  2BG8 B;  5AEB A;  2WRS A;  5ACV A;  1JJT A;  3RKK A;  2FU6 A;  5HIS A;  4C1C A;  2GCU A;  3I13 A;  3X2Y A;  4AWY B;  1KO2 A;  4C09 A;  4C1E A;  5B15 A;  5LM6 A;  2BC2 A;  3ZWF A;  1SML A;  2HB9 A;  2YNW A;  3SD9 A;  1XTO A;  5KIK A;  3IEK A;  5EVK A;  2OHH A;  4KEP A;  4RAW A;  4Z5Z A;  3BV6 A;  3P2U A;  2BIB A;  3ZQ4 A;  4J5H A;  4TZB A;  4KEQ A;  2M5D A;  2DOO A;  4XUK A;  4XWT A;  1WW1 A;  5EV8 A;  4TYF A;  3I11 A;  3KNS A;  4ZO3 A;  4EY2 A;  5FQC A;  3SBL A;  1KR3 A;  2GFJ A;  2P4Z A;  5HIP A;  3QH8 A;  4EYF A;  2FHX A;  2P18 A;  3ZR9 A;  5LCH A;  1JJE A;  5LCA A;  4D1T A;  2UYX A;  3IDZ A;  1BVT A;  3DH8 A;  3RPC A;  1BMC A;  4AD9 A;  2YNT A;  5K4N A;  2I7V A;  4D02 A;  4RBS A;  4WD6 A;  5HH5 A;  3F9O A;  5ACR A;  5A0T A;  3S0Z A;  1K07 A;  4TYT A;  2M5C A;  2QDT A;  2R2D A;  2AIO A;  1E5D A;  5ACS A;  5ACW A;  2BG8 A;  3AF5 A;  4PVT A;  3VPE A;  2GFK A;  2WHG A;  5A0V A;  4F6H A;  3JXP A;  4AX1 B;  3IOG A;  4UWR B;  2DKF A;  2Q9U A;  4UAM A;  2YNV B;  1QH5 A;  2Q0I A;  4EXS A;  5B3R A;  4F6Z A;  4Z60 A;  3BC2 A;  1ZNB A;  5EVB A;  3IEL A;  2BFK A;  2XR1 A;  5EWA A;  3X2X A;  4P62 A;  3ADR A; 
#chains in the Genus database with same CATH topology
 2OHI A;  2QIN A;  2BG7 A;  2GKL A;  4ZO2 A;  2VW8 A;  3T9M A;  4J5F A;  4C1D A;  4NQ4 A;  3SFP A;  2BG6 A;  3ESH A;  4C1F A;  3PG4 A;  2YCB A;  5EV6 A;  5K0W A;  4JO0 A;  1X8G A;  4AX0 B;  3PY5 A;  1VGN A;  5LCF A;  3TP9 A;  3X2Z A;  4D1W A;  4UWS B;  4EYB A;  4EXY A;  5AHO A;  2P1E A;  3WXC A;  2E7Y A;  1A7T A;  5ACQ A;  4YSL A;  3IE2 A;  2FU8 A;  2FU7 A;  5EVD A;  4BZ3 A;  4D1U A;  5FQB A;  1DXK A;  3DHB A;  4B87 A;  5HIO A;  2I7T A;  1BC2 A;  4LE6 A;  4RL0 A;  3DHA A;  4ZEJ A;  5ACT A;  4FSB A;  4V0H A;  5AYA A;  3VQZ A;  5AXR A;  4NQ6 A;  1MQO A;  4RAM A;  4FR7 A;  2NXA A;  1DDK A;  3BK1 A;  4BP0 A;  2NZF A;  2YNV A;  5A5Z A;  4GYU A;  2FM6 A;  5ACP A;  2OHJ A;  3FCZ A;  2YHE A;  4YSB A;  5LE1 A;  3T3N A;  4RM5 A;  1JT1 A;  5A23 A;  2Y8B A;  4TZF A;  5IQK A;  1X8H A;  2BFZ B;  3AF6 A;  2BTN A;  3AJ3 A;  5ACU A;  4Z6X A;  3A4Y A;  3KNR A;  4UWP B;  5DPX A;  1YCH A;  2QED A;  1WRA A;  2CG2 A;  1M2X A;  1WUP A;  1ZKP A;  2ZO4 A;  2CG3 A;  3L6N A;  1YCG A;  4GYQ A;  4HL1 A;  4EYL A;  5HIQ A;  1VME A;  2A7M A;  5ACX A;  1L9Y A;  2CFU A;  2YZ3 A;  4AV7 A;  3RKJ A;  2ZNB A;  2GMN A;  5EH9 A;  4UBQ A;  2QJS A;  1Y44 A;  2BFL A;  4UWO B;  3SRX A;  3I14 A;  5HH4 A;  2YNU A;  4YSK A;  4U4L A;  3I0V A;  4NQ5 A;  2BGA A;  2CFZ A;  5AXO A;  2WYM C;  1XM8 A;  2CBN A;  5LLD A;  3LVZ A;  3FAI A;  1DD6 A;  5LSC A;  3T3O A;  5HH6 A;  3SPU A;  1QH3 A;  2WYM A;  2Q42 A;  2XF4 A;  3DHC A;  2BMI A;  5LMC A;  2BG2 A;  4UA4 A;  2BR6 A;  1A8T A;  3IOF A;  3Q6V A;  5FQA A;  3X30 A;  4DIL A;  5EHT A;  5B1U A;  2FK6 A;  4HKY A;  1P9E A;  4HL2 A;  4XWW A;  3IE0 A;  4GCW A;  5KIL A;  2QDS A;  4RL2 A;  1YCF A;  5K4M A;  2P97 A;  3BK2 A;  4EFZ A;  4D1V A;  4CHL A;  4DIK A;  2Y8A A;  4ZNB A;  5EW0 A;  4PDX A;  3IE1 A;  2FU9 A;  2BFZ A;  4TZ9 A;  1WUO A;  2Q0J A;  3KL7 A;  4NQ2 A;  2WYL A;  5LS3 A;  5AHR A;  1X8I A;  4Z7R A;  2ZZI A;  3IEM A;  2FHX B;  5A87 A;  4TZE A;  2Y87 A;  2NYP A;  4C1G A;  3MD7 A;  4FEK A;  3ZNB A;  3I15 A;  4Z67 A;  3G1P A;  4H0D A;  3R2U A;  2NZE A;  2YNT B;  2ZWR A;  4Z5Y A;  2H6A A;  1HLK A;  1ZTC A;  3PY6 A;  5K4K A;  4O98 A;  4AWZ A;  2I7X A;  3H3E A;  1KO3 A;  3SW3 A;  4C1H A;  4PVO A;  1VJN A;  2AZ4 A;  2BG8 B;  5AEB A;  2WRS A;  5ACV A;  1JJT A;  3RKK A;  2FU6 A;  5HIS A;  4C1C A;  2GCU A;  3I13 A;  3X2Y A;  4AWY B;  1KO2 A;  4C09 A;  4C1E A;  5B15 A;  5LM6 A;  2BC2 A;  3ZWF A;  1SML A;  2HB9 A;  2YNW A;  3SD9 A;  5AJL A;  1XTO A;  5KIK A;  3IEK A;  5EVK A;  2OHH A;  4KEP A;  4RAW A;  4Z5Z A;  3BV6 A;  3P2U A;  2BIB A;  3ZQ4 A;  4J5H A;  4TZB A;  4KEQ A;  2M5D A;  2DOO A;  4XUK A;  4XWT A;  1WW1 A;  5EV8 A;  4TYF A;  3I11 A;  3KNS A;  4ZO3 A;  4EY2 A;  5FQC A;  5AIJ A;  4NUR A;  3SBL A;  1KR3 A;  2GFJ A;  2P4Z A;  5HIP A;  3QH8 A;  4EYF A;  2FHX A;  2P18 A;  3ZR9 A;  5LCH A;  1JJE A;  5LCA A;  4D1T A;  2UYX A;  3IDZ A;  1BVT A;  3DH8 A;  3RPC A;  1BMC A;  4AD9 A;  2YNT A;  5K4N A;  2I7V A;  4D02 A;  4RBS A;  4WD6 A;  4AXH A;  5HH5 A;  3F9O A;  5ACR A;  5A0T A;  3S0Z A;  1K07 A;  4TYT A;  2M5C A;  2QDT A;  2R2D A;  2AIO A;  1E5D A;  5ACS A;  5ACW A;  2BG8 A;  3AF5 A;  4PVT A;  3VPE A;  2GFK A;  2WHG A;  5A0V A;  4F6H A;  3JXP A;  4AX1 B;  3IOG A;  4UWR B;  2DKF A;  2Q9U A;  4UAM A;  2YNV B;  1QH5 A;  2Q0I A;  4EXS A;  5B3R A;  4F6Z A;  4Z60 A;  3BC2 A;  1ZNB A;  5EVB A;  3IEL A;  2BFK A;  2XR1 A;  5EWA A;  3X2X A;  4P62 A;  3ADR A; 
#chains in the Genus database with same CATH homology
 2OHI A;  2QIN A;  2BG7 A;  2GKL A;  4ZO2 A;  2VW8 A;  3T9M A;  4J5F A;  4C1D A;  4NQ4 A;  3SFP A;  2BG6 A;  3ESH A;  4C1F A;  3PG4 A;  2YCB A;  5EV6 A;  5K0W A;  4JO0 A;  1X8G A;  4AX0 B;  3PY5 A;  1VGN A;  5LCF A;  3TP9 A;  3X2Z A;  4D1W A;  4UWS B;  4EYB A;  4EXY A;  5AHO A;  2P1E A;  3WXC A;  2E7Y A;  1A7T A;  5ACQ A;  4YSL A;  3IE2 A;  2FU8 A;  2FU7 A;  5EVD A;  4BZ3 A;  4D1U A;  5FQB A;  1DXK A;  3DHB A;  4B87 A;  5HIO A;  2I7T A;  1BC2 A;  4LE6 A;  4RL0 A;  3DHA A;  4ZEJ A;  5ACT A;  4FSB A;  4V0H A;  5AYA A;  3VQZ A;  5AXR A;  4NQ6 A;  1MQO A;  4RAM A;  4FR7 A;  2NXA A;  1DDK A;  3BK1 A;  4BP0 A;  2NZF A;  2YNV A;  5A5Z A;  4GYU A;  2FM6 A;  5ACP A;  2OHJ A;  3FCZ A;  4YSB A;  5LE1 A;  3T3N A;  4RM5 A;  1JT1 A;  2Y8B A;  4TZF A;  5IQK A;  1X8H A;  2BFZ B;  3AF6 A;  2BTN A;  3AJ3 A;  5ACU A;  4Z6X A;  3A4Y A;  3KNR A;  4UWP B;  5DPX A;  1YCH A;  2QED A;  1WRA A;  1M2X A;  1WUP A;  1ZKP A;  2ZO4 A;  3L6N A;  1YCG A;  4GYQ A;  4HL1 A;  4EYL A;  5HIQ A;  1VME A;  2A7M A;  5ACX A;  1L9Y A;  2YZ3 A;  3RKJ A;  2ZNB A;  2GMN A;  5EH9 A;  4UBQ A;  2QJS A;  1Y44 A;  2BFL A;  4UWO B;  3SRX A;  3I14 A;  5HH4 A;  2YNU A;  4YSK A;  4U4L A;  3I0V A;  4NQ5 A;  2BGA A;  5AXO A;  2WYM C;  1XM8 A;  2CBN A;  5LLD A;  3LVZ A;  3FAI A;  1DD6 A;  5LSC A;  3T3O A;  5HH6 A;  3SPU A;  1QH3 A;  2WYM A;  2Q42 A;  2XF4 A;  3DHC A;  2BMI A;  5LMC A;  2BG2 A;  4UA4 A;  2BR6 A;  1A8T A;  3IOF A;  3Q6V A;  5FQA A;  3X30 A;  4DIL A;  5EHT A;  5B1U A;  2FK6 A;  4HKY A;  1P9E A;  4HL2 A;  4XWW A;  3IE0 A;  4GCW A;  5KIL A;  2QDS A;  4RL2 A;  1YCF A;  5K4M A;  2P97 A;  3BK2 A;  4EFZ A;  4D1V A;  4CHL A;  4DIK A;  2Y8A A;  4ZNB A;  5EW0 A;  3IE1 A;  2FU9 A;  2BFZ A;  4TZ9 A;  1WUO A;  2Q0J A;  3KL7 A;  4NQ2 A;  2WYL A;  5LS3 A;  5AHR A;  1X8I A;  4Z7R A;  2ZZI A;  3IEM A;  2FHX B;  5A87 A;  4TZE A;  2Y87 A;  2NYP A;  4C1G A;  3MD7 A;  4FEK A;  3ZNB A;  3I15 A;  4Z67 A;  3G1P A;  4H0D A;  3R2U A;  2NZE A;  2YNT B;  2ZWR A;  4Z5Y A;  2H6A A;  1HLK A;  1ZTC A;  3PY6 A;  5K4K A;  4O98 A;  4AWZ A;  2I7X A;  3H3E A;  1KO3 A;  3SW3 A;  4C1H A;  4PVO A;  1VJN A;  2AZ4 A;  2BG8 B;  5AEB A;  2WRS A;  5ACV A;  1JJT A;  3RKK A;  2FU6 A;  5HIS A;  4C1C A;  2GCU A;  3I13 A;  3X2Y A;  4AWY B;  1KO2 A;  4C09 A;  4C1E A;  5B15 A;  5LM6 A;  2BC2 A;  3ZWF A;  1SML A;  2HB9 A;  2YNW A;  3SD9 A;  1XTO A;  5KIK A;  3IEK A;  5EVK A;  2OHH A;  4KEP A;  4RAW A;  4Z5Z A;  3BV6 A;  3P2U A;  2BIB A;  3ZQ4 A;  4J5H A;  4TZB A;  4KEQ A;  2M5D A;  2DOO A;  4XUK A;  4XWT A;  1WW1 A;  5EV8 A;  4TYF A;  3I11 A;  3KNS A;  4ZO3 A;  4EY2 A;  5FQC A;  3SBL A;  1KR3 A;  2GFJ A;  2P4Z A;  5HIP A;  3QH8 A;  4EYF A;  2FHX A;  2P18 A;  3ZR9 A;  5LCH A;  1JJE A;  5LCA A;  4D1T A;  2UYX A;  3IDZ A;  1BVT A;  3DH8 A;  3RPC A;  1BMC A;  4AD9 A;  2YNT A;  5K4N A;  2I7V A;  4D02 A;  4RBS A;  4WD6 A;  5HH5 A;  3F9O A;  5ACR A;  5A0T A;  3S0Z A;  1K07 A;  4TYT A;  2M5C A;  2QDT A;  2R2D A;  2AIO A;  1E5D A;  5ACS A;  5ACW A;  2BG8 A;  3AF5 A;  4PVT A;  3VPE A;  2GFK A;  2WHG A;  5A0V A;  4F6H A;  3JXP A;  4AX1 B;  3IOG A;  4UWR B;  2DKF A;  2Q9U A;  4UAM A;  2YNV B;  1QH5 A;  2Q0I A;  4EXS A;  5B3R A;  4F6Z A;  4Z60 A;  3BC2 A;  1ZNB A;  5EVB A;  3IEL A;  2BFK A;  2XR1 A;  5EWA A;  3X2X A;  4P62 A;  3ADR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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