5K4KA

Directed evolutionary changes in mbl super family - ndm-1 round 10 crystal-4
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
228
structure length
228
Chain Sequence
DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Enzyme evolvability is contingent on the initial sequence background
rcsb
molecule tags Hydrolase
source organism Klebsiella pneumoniae
molecule keywords Metallo-beta-lactamase type 2
total genus 70
structure length 228
sequence length 228
chains with identical sequence K
ec nomenclature
pdb deposition date 2016-05-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5k4kA00
5LCFA 4Z5YA 4UWOB 3DH8A 4V0HA 1VJNA 1WUOA 4UA4A 4EYFA 2M5CA 2YNTB 2YCBA 5ACUA 3R2UA 4EXSA 4NQ5A 3BV6A 3L6NA 4UWSB 4DIKA 4ZNBA 4ZO3A 3T3OA 3A4YA 4P62A 3I0VA 2BG2A 4F6ZA 3BC2A 4AWZA 4D1WA 5ACQA 2Q0JA 3DHAA 2QJSA 2BG7A 3DHCA 5FQAA 3P2UA 4TZBA 1JJTA 2DKFA 4CHLA 3KNSA 3T9MA 5A0VA 5EHTA 5HH4A 5ACVA 1ZKPA 3IEKA 2WRSA 3IE0A 4UWRB 3QH8A 5LSCA 4TYFA 1KO2A 5A87A 4C1CA 3SFPA 2QEDA 2Q0IA 2GMNA 3AF5A 1P9EA 2QDTA 5B1UA 4UBQA 3G1PA 4BP0A 5LLDA 5B3RA 2GKLA 5HIQA 4RL2A 3SBLA 5ACTA 2WYMA 1YCFA 3KL7A 2HB9A 5ACXA 5LS3A 1QH3A 3TP9A 2FHXB 5LMCA 3IELA 2NXAA 2YNVA 2GFKA 5KIKA 4GYQA 1MQOA 5HH6A 2UYXA 4HL1A 3I11A 3ZQ4A 2YNWA 1VGNA 2WYLA 1BVTA 5AHOA 4C1HA 4HKYA 3IOGA 2FK6A 4D1TA 5HIPA 3WXCA 5AXRA 4UAMA 2Y8AA 4TZ9A 3BK1A 3PG4A 5K4KA 5AYAA 4B87A 3S0ZA 2BFKA 4O98A 1A8TA 2I7VA 1KO3A 5LCHA 3SW3A 3SRXA 2BTNA 3Q6VA 5EVDA 5FQCA 4FEKA 3IE2A 2YNUA 5EV8A 2XR1A 4NQ4A 5KILA 4RM5A 4EYLA 1XTOA 2YZ3A 4F6HA 3X30A 4YSLA 2YNTA 2ZNBA 4KEQA 4NQ6A 5K4MA 4WD6A 5A0TA 1DXKA 3F9OA 3I13A 1JJEA 4AX1B 3ZWFA 5IQKA 2BFZA 1BC2A 3ESHA 2BG8B 2I7TA 4PVOA 2BIBA 3PY6A 3AJ3A 2QINA 5FQBA 2Y87A 4AX0B 3IE1A 2NYPA 3RKKA 3ADRA 5ACSA 4J5HA 2OHIA 1JT1A 3RKJA 4RBSA 2M5DA 4YSKA 4RAMA 2P18A 2BR6A 5EVBA 3ZR9A 3PY5A 2A7MA 2OHJA 1QH5A 4YSBA 4RAWA 3DHBA 5HISA 5LCAA 2FU6A 4XWTA 3X2YA 1YCGA 5EV6A 4EYBA 4C1GA 4TZEA 2FM6A 3X2XA 4Z60A 2FHXA 4C1FA 2CBNA 4C1EA 4C09A 4DILA 4D02A 1X8IA 4ZO2A 3FCZA 3SPUA 4AWYB 2OHHA 5LM6A 5K4NA 2AIOA 2GCUA 2DOOA 2BG6A 4TYTA 2BMIA 4Z7RA 3VPEA 2BC2A 5EH9A 5HH5A 3X2ZA 5EW0A 4Z67A 2FU7A 4J5FA 2NZEA 1HLKA 3KNRA 5LE1A 3FAIA 2FU8A 1L9YA 1ZNBA 1ZTCA 3MD7A 1A7TA 1BMCA 1WRAA 1DDKA 5ACRA 3VQZA 3I14A 3AF6A 1X8HA 5ACWA 2I7XA 5AXOA 2WHGA 4EY2A 3JXPA 2XF4A 3IEMA 4TZFA 4H0DA 5ACPA 4KEPA 5AEBA 4D1VA 2BFZB 4EFZA 4HL2A 3I15A 4GYUA 2WYMC 2AZ4A 2QDSA 2ZWRA 2ZO4A 4FSBA 4RL0A 2GFJA 2E7YA 5DPXA 1WUPA 1YCHA 1KR3A 1XM8A 3RPCA 2BG8A 3SD9A 4C1DA 4U4LA 1M2XA 4EXYA 2R2DA 4Z6XA 5B15A 4GCWA 3IOFA 4PVTA 3ZNBA 2ZZIA 1X8GA 2VW8A 2YNVB 3T3NA 5EWAA 2Q9UA 3BK2A 5EVKA 1SMLA 1Y44A 4FR7A 2NZFA 2BFLA 4NQ2A 1WW1A 2P97A 5K0WA 1E5DA 5A5ZA 4XWWA 4Z5ZA 2P4ZA 4BZ3A 5HIOA 2P1EA 2H6AA 4JO0A 3IDZA 4XUKA 4LE6A 2BGAA 1DD6A 1VMEA 2FU9A 4ZEJA 2Q42A 2Y8BA 1K07A 3H3EA 3LVZA 4AD9A 4D1UA 5AHRA 4UWPB
chains in the Genus database with same CATH superfamily
5LCFA 4Z5YA 4UWOB 3DH8A 4V0HA 4PDXA 1VJNA 1WUOA 4UA4A 4EYFA 2M5CA 2YNTB 2YCBA 5ACUA 3R2UA 4EXSA 4NQ5A 3BV6A 3L6NA 4UWSB 4DIKA 4ZNBA 4ZO3A 3T3OA 3A4YA 4P62A 3I0VA 2BG2A 4F6ZA 3BC2A 4AWZA 4D1WA 5ACQA 2Q0JA 3DHAA 2QJSA 2BG7A 3DHCA 5FQAA 3P2UA 4TZBA 1JJTA 5AJLA 2DKFA 4CHLA 3KNSA 3T9MA 5A0VA 5EHTA 5HH4A 5ACVA 1ZKPA 3IEKA 2WRSA 3IE0A 4UWRB 3QH8A 5LSCA 4TYFA 1KO2A 5A87A 4C1CA 3SFPA 2QEDA 2Q0IA 2GMNA 3AF5A 1P9EA 2QDTA 5B1UA 4UBQA 3G1PA 4BP0A 5LLDA 5B3RA 2GKLA 5HIQA 2CG2A 4RL2A 3SBLA 5ACTA 2WYMA 1YCFA 3KL7A 2HB9A 5ACXA 5LS3A 1QH3A 3TP9A 2FHXB 5LMCA 3IELA 2NXAA 2YNVA 2GFKA 5KIKA 4GYQA 2CFUA 1MQOA 5HH6A 2UYXA 4HL1A 3I11A 3ZQ4A 2YNWA 1VGNA 2WYLA 1BVTA 5AHOA 4C1HA 4HKYA 3IOGA 2FK6A 2CFZA 4D1TA 5HIPA 3WXCA 5AXRA 4UAMA 2Y8AA 4TZ9A 3BK1A 3PG4A 5K4KA 5AYAA 4B87A 3S0ZA 2BFKA 4O98A 1A8TA 2I7VA 1KO3A 5LCHA 3SW3A 2CG3A 3SRXA 2BTNA 3Q6VA 5EVDA 5FQCA 4FEKA 3IE2A 2YNUA 5EV8A 2XR1A 4NQ4A 5KILA 4RM5A 4EYLA 1XTOA 2YZ3A 4F6HA 3X30A 4YSLA 2YNTA 2ZNBA 4KEQA 4NQ6A 5K4MA 4WD6A 5A0TA 1DXKA 3F9OA 3I13A 1JJEA 4AX1B 3ZWFA 5IQKA 2BFZA 1BC2A 3ESHA 2BG8B 2I7TA 4PVOA 2BIBA 3PY6A 3AJ3A 2QINA 5FQBA 2Y87A 4AX0B 3IE1A 2NYPA 3RKKA 3ADRA 5ACSA 4J5HA 2OHIA 1JT1A 3RKJA 4RBSA 2M5DA 4YSKA 4RAMA 2P18A 2BR6A 5EVBA 3ZR9A 3PY5A 2A7MA 2OHJA 1QH5A 4YSBA 4RAWA 3DHBA 5HISA 5LCAA 4NURA 2FU6A 4AV7A 4XWTA 3X2YA 1YCGA 5EV6A 4EYBA 4C1GA 4TZEA 2FM6A 3X2XA 4Z60A 2FHXA 4C1FA 2CBNA 4C1EA 4C09A 4DILA 4D02A 1X8IA 4ZO2A 3FCZA 3SPUA 4AWYB 2OHHA 5LM6A 5K4NA 2AIOA 2GCUA 2DOOA 2BG6A 4TYTA 2BMIA 4Z7RA 3VPEA 2BC2A 5AIJA 2YHEA 5EH9A 5HH5A 3X2ZA 5EW0A 4Z67A 2FU7A 4J5FA 2NZEA 1HLKA 3KNRA 5LE1A 3FAIA 2FU8A 1L9YA 1ZNBA 1ZTCA 3MD7A 1A7TA 1BMCA 1WRAA 1DDKA 5ACRA 3VQZA 3I14A 3AF6A 1X8HA 5ACWA 2I7XA 5AXOA 2WHGA 4EY2A 3JXPA 2XF4A 3IEMA 4TZFA 4H0DA 5ACPA 4KEPA 5AEBA 4D1VA 2BFZB 4EFZA 4HL2A 3I15A 4GYUA 2WYMC 2AZ4A 2QDSA 2ZWRA 2ZO4A 4FSBA 4RL0A 2GFJA 4AXHA 2E7YA 5DPXA 1WUPA 1YCHA 1KR3A 1XM8A 3RPCA 2BG8A 5A23A 3SD9A 4C1DA 4U4LA 1M2XA 4EXYA 2R2DA 4Z6XA 5B15A 4GCWA 3IOFA 4PVTA 3ZNBA 2ZZIA 1X8GA 2VW8A 2YNVB 3T3NA 5EWAA 2Q9UA 3BK2A 5EVKA 1SMLA 1Y44A 4FR7A 2NZFA 2BFLA 4NQ2A 1WW1A 2P97A 5K0WA 1E5DA 5A5ZA 4XWWA 4Z5ZA 2P4ZA 4BZ3A 5HIOA 2P1EA 2H6AA 4JO0A 3IDZA 4XUKA 4LE6A 2BGAA 1DD6A 1VMEA 2FU9A 4ZEJA 2Q42A 2Y8BA 1K07A 3H3EA 3LVZA 4AD9A 4D1UA 5AHRA 4UWPB
chains in the Genus database with same CATH topology
5LCFA 4Z5YA 4UWOB 3DH8A 4V0HA 1VJNA 1WUOA 4UA4A 4EYFA 2M5CA 2YNTB 2YCBA 5ACUA 3R2UA 4EXSA 4NQ5A 3BV6A 3L6NA 4UWSB 4DIKA 4ZNBA 4ZO3A 3T3OA 3A4YA 4P62A 3I0VA 2BG2A 4F6ZA 3BC2A 4AWZA 4D1WA 5ACQA 2Q0JA 3DHAA 2QJSA 2BG7A 3DHCA 5FQAA 3P2UA 4TZBA 1JJTA 2DKFA 4CHLA 3KNSA 3T9MA 5A0VA 5EHTA 5HH4A 5ACVA 1ZKPA 3IEKA 2WRSA 3IE0A 4UWRB 3QH8A 5LSCA 4TYFA 1KO2A 5A87A 4C1CA 3SFPA 2QEDA 2Q0IA 2GMNA 3AF5A 1P9EA 2QDTA 5B1UA 4UBQA 3G1PA 4BP0A 5LLDA 5B3RA 2GKLA 5HIQA 4RL2A 3SBLA 5ACTA 2WYMA 1YCFA 3KL7A 2HB9A 5ACXA 5LS3A 1QH3A 3TP9A 2FHXB 5LMCA 3IELA 2NXAA 2YNVA 2GFKA 5KIKA 4GYQA 1MQOA 5HH6A 2UYXA 4HL1A 3I11A 3ZQ4A 2YNWA 1VGNA 2WYLA 1BVTA 5AHOA 4C1HA 4HKYA 3IOGA 2FK6A 4D1TA 5HIPA 3WXCA 5AXRA 4UAMA 2Y8AA 4TZ9A 3BK1A 3PG4A 5K4KA 5AYAA 4B87A 3S0ZA 2BFKA 4O98A 1A8TA 2I7VA 1KO3A 5LCHA 3SW3A 3SRXA 2BTNA 3Q6VA 5EVDA 5FQCA 4FEKA 3IE2A 2YNUA 5EV8A 2XR1A 4NQ4A 5KILA 4RM5A 4EYLA 1XTOA 2YZ3A 4F6HA 3X30A 4YSLA 2YNTA 2ZNBA 4KEQA 4NQ6A 5K4MA 4WD6A 5A0TA 1DXKA 3F9OA 3I13A 1JJEA 4AX1B 3ZWFA 5IQKA 2BFZA 1BC2A 3ESHA 2BG8B 2I7TA 4PVOA 2BIBA 3PY6A 3AJ3A 2QINA 5FQBA 2Y87A 4AX0B 3IE1A 2NYPA 3RKKA 3ADRA 5ACSA 4J5HA 2OHIA 1JT1A 3RKJA 4RBSA 2M5DA 4YSKA 4RAMA 2P18A 2BR6A 5EVBA 3ZR9A 3PY5A 2A7MA 2OHJA 1QH5A 4YSBA 4RAWA 3DHBA 5HISA 5LCAA 2FU6A 4XWTA 3X2YA 1YCGA 5EV6A 4EYBA 4C1GA 4TZEA 2FM6A 3X2XA 4Z60A 2FHXA 4C1FA 2CBNA 4C1EA 4C09A 4DILA 4D02A 1X8IA 4ZO2A 3FCZA 3SPUA 4AWYB 2OHHA 5LM6A 5K4NA 2AIOA 2GCUA 2DOOA 2BG6A 4TYTA 2BMIA 4Z7RA 3VPEA 2BC2A 5EH9A 5HH5A 3X2ZA 5EW0A 4Z67A 2FU7A 4J5FA 2NZEA 1HLKA 3KNRA 5LE1A 3FAIA 2FU8A 1L9YA 1ZNBA 1ZTCA 3MD7A 1A7TA 1BMCA 1WRAA 1DDKA 5ACRA 3VQZA 3I14A 3AF6A 1X8HA 5ACWA 2I7XA 5AXOA 2WHGA 4EY2A 3JXPA 2XF4A 3IEMA 4TZFA 4H0DA 5ACPA 4KEPA 5AEBA 4D1VA 2BFZB 4EFZA 4HL2A 3I15A 4GYUA 2WYMC 2AZ4A 2QDSA 2ZWRA 2ZO4A 4FSBA 4RL0A 2GFJA 2E7YA 5DPXA 1WUPA 1YCHA 1KR3A 1XM8A 3RPCA 2BG8A 3SD9A 4C1DA 4U4LA 1M2XA 4EXYA 2R2DA 4Z6XA 5B15A 4GCWA 3IOFA 4PVTA 3ZNBA 2ZZIA 1X8GA 2VW8A 2YNVB 3T3NA 5EWAA 2Q9UA 3BK2A 5EVKA 1SMLA 1Y44A 4FR7A 2NZFA 2BFLA 4NQ2A 1WW1A 2P97A 5K0WA 1E5DA 5A5ZA 4XWWA 4Z5ZA 2P4ZA 4BZ3A 5HIOA 2P1EA 2H6AA 4JO0A 3IDZA 4XUKA 4LE6A 2BGAA 1DD6A 1VMEA 2FU9A 4ZEJA 2Q42A 2Y8BA 1K07A 3H3EA 3LVZA 4AD9A 4D1UA 5AHRA 4UWPB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5LCF A;  4Z5Y A;  4UWO B;  3DH8 A;  4V0H A;  1VJN A;  1WUO A;  4UA4 A;  4EYF A;  2M5C A;  2YNT B;  2YCB A;  5ACU A;  3R2U A;  4EXS A;  4NQ5 A;  3BV6 A;  3L6N A;  4UWS B;  4DIK A;  4ZNB A;  4ZO3 A;  3T3O A;  3A4Y A;  4P62 A;  3I0V A;  2BG2 A;  4F6Z A;  3BC2 A;  4AWZ A;  4D1W A;  5ACQ A;  2Q0J A;  3DHA A;  2QJS A;  2BG7 A;  3DHC A;  5FQA A;  3P2U A;  4TZB A;  1JJT A;  2DKF A;  4CHL A;  3KNS A;  3T9M A;  5A0V A;  5EHT A;  5HH4 A;  5ACV A;  1ZKP A;  3IEK A;  2WRS A;  3IE0 A;  4UWR B;  3QH8 A;  5LSC A;  4TYF A;  1KO2 A;  5A87 A;  4C1C A;  3SFP A;  2QED A;  2Q0I A;  2GMN A;  3AF5 A;  1P9E A;  2QDT A;  5B1U A;  4UBQ A;  3G1P A;  4BP0 A;  5LLD A;  5B3R A;  2GKL A;  5HIQ A;  4RL2 A;  3SBL A;  5ACT A;  2WYM A;  1YCF A;  3KL7 A;  2HB9 A;  5ACX A;  5LS3 A;  1QH3 A;  3TP9 A;  2FHX B;  5LMC A;  3IEL A;  2NXA A;  2YNV A;  2GFK A;  5KIK A;  4GYQ A;  1MQO A;  5HH6 A;  2UYX A;  4HL1 A;  3I11 A;  3ZQ4 A;  2YNW A;  1VGN A;  2WYL A;  1BVT A;  5AHO A;  4C1H A;  4HKY A;  3IOG A;  2FK6 A;  4D1T A;  5HIP A;  3WXC A;  5AXR A;  4UAM A;  2Y8A A;  4TZ9 A;  3BK1 A;  3PG4 A;  5K4K A;  5AYA A;  4B87 A;  3S0Z A;  2BFK A;  4O98 A;  1A8T A;  2I7V A;  1KO3 A;  5LCH A;  3SW3 A;  3SRX A;  2BTN A;  3Q6V A;  5EVD A;  5FQC A;  4FEK A;  3IE2 A;  2YNU A;  5EV8 A;  2XR1 A;  4NQ4 A;  5KIL A;  4RM5 A;  4EYL A;  1XTO A;  2YZ3 A;  4F6H A;  3X30 A;  4YSL A;  2YNT A;  2ZNB A;  4KEQ A;  4NQ6 A;  5K4M A;  4WD6 A;  5A0T A;  1DXK A;  3F9O A;  3I13 A;  1JJE A;  4AX1 B;  3ZWF A;  5IQK A;  2BFZ A;  1BC2 A;  3ESH A;  2BG8 B;  2I7T A;  4PVO A;  2BIB A;  3PY6 A;  3AJ3 A;  2QIN A;  5FQB A;  2Y87 A;  4AX0 B;  3IE1 A;  2NYP A;  3RKK A;  3ADR A;  5ACS A;  4J5H A;  2OHI A;  1JT1 A;  3RKJ A;  4RBS A;  2M5D A;  4YSK A;  4RAM A;  2P18 A;  2BR6 A;  5EVB A;  3ZR9 A;  3PY5 A;  2A7M A;  2OHJ A;  1QH5 A;  4YSB A;  4RAW A;  3DHB A;  5HIS A;  5LCA A;  2FU6 A;  4XWT A;  3X2Y A;  1YCG A;  5EV6 A;  4EYB A;  4C1G A;  4TZE A;  2FM6 A;  3X2X A;  4Z60 A;  2FHX A;  4C1F A;  2CBN A;  4C1E A;  4C09 A;  4DIL A;  4D02 A;  1X8I A;  4ZO2 A;  3FCZ A;  3SPU A;  4AWY B;  2OHH A;  5LM6 A;  5K4N A;  2AIO A;  2GCU A;  2DOO A;  2BG6 A;  4TYT A;  2BMI A;  4Z7R A;  3VPE A;  2BC2 A;  5EH9 A;  5HH5 A;  3X2Z A;  5EW0 A;  4Z67 A;  2FU7 A;  4J5F A;  2NZE A;  1HLK A;  3KNR A;  5LE1 A;  3FAI A;  2FU8 A;  1L9Y A;  1ZNB A;  1ZTC A;  3MD7 A;  1A7T A;  1BMC A;  1WRA A;  1DDK A;  5ACR A;  3VQZ A;  3I14 A;  3AF6 A;  1X8H A;  5ACW A;  2I7X A;  5AXO A;  2WHG A;  4EY2 A;  3JXP A;  2XF4 A;  3IEM A;  4TZF A;  4H0D A;  5ACP A;  4KEP A;  5AEB A;  4D1V A;  2BFZ B;  4EFZ A;  4HL2 A;  3I15 A;  4GYU A;  2WYM C;  2AZ4 A;  2QDS A;  2ZWR A;  2ZO4 A;  4FSB A;  4RL0 A;  2GFJ A;  2E7Y A;  5DPX A;  1WUP A;  1YCH A;  1KR3 A;  1XM8 A;  3RPC A;  2BG8 A;  3SD9 A;  4C1D A;  4U4L A;  1M2X A;  4EXY A;  2R2D A;  4Z6X A;  5B15 A;  4GCW A;  3IOF A;  4PVT A;  3ZNB A;  2ZZI A;  1X8G A;  2VW8 A;  2YNV B;  3T3N A;  5EWA A;  2Q9U A;  3BK2 A;  5EVK A;  1SML A;  1Y44 A;  4FR7 A;  2NZF A;  2BFL A;  4NQ2 A;  1WW1 A;  2P97 A;  5K0W A;  1E5D A;  5A5Z A;  4XWW A;  4Z5Z A;  2P4Z A;  4BZ3 A;  5HIO A;  2P1E A;  2H6A A;  4JO0 A;  3IDZ A;  4XUK A;  4LE6 A;  2BGA A;  1DD6 A;  1VME A;  2FU9 A;  4ZEJ A;  2Q42 A;  2Y8B A;  1K07 A;  3H3E A;  3LVZ A;  4AD9 A;  4D1U A;  5AHR A;  4UWP B; 
#chains in the Genus database with same CATH topology
 5LCF A;  4Z5Y A;  4UWO B;  3DH8 A;  4V0H A;  4PDX A;  1VJN A;  1WUO A;  4UA4 A;  4EYF A;  2M5C A;  2YNT B;  2YCB A;  5ACU A;  3R2U A;  4EXS A;  4NQ5 A;  3BV6 A;  3L6N A;  4UWS B;  4DIK A;  4ZNB A;  4ZO3 A;  3T3O A;  3A4Y A;  4P62 A;  3I0V A;  2BG2 A;  4F6Z A;  3BC2 A;  4AWZ A;  4D1W A;  5ACQ A;  2Q0J A;  3DHA A;  2QJS A;  2BG7 A;  3DHC A;  5FQA A;  3P2U A;  4TZB A;  1JJT A;  5AJL A;  2DKF A;  4CHL A;  3KNS A;  3T9M A;  5A0V A;  5EHT A;  5HH4 A;  5ACV A;  1ZKP A;  3IEK A;  2WRS A;  3IE0 A;  4UWR B;  3QH8 A;  5LSC A;  4TYF A;  1KO2 A;  5A87 A;  4C1C A;  3SFP A;  2QED A;  2Q0I A;  2GMN A;  3AF5 A;  1P9E A;  2QDT A;  5B1U A;  4UBQ A;  3G1P A;  4BP0 A;  5LLD A;  5B3R A;  2GKL A;  5HIQ A;  2CG2 A;  4RL2 A;  3SBL A;  5ACT A;  2WYM A;  1YCF A;  3KL7 A;  2HB9 A;  5ACX A;  5LS3 A;  1QH3 A;  3TP9 A;  2FHX B;  5LMC A;  3IEL A;  2NXA A;  2YNV A;  2GFK A;  5KIK A;  4GYQ A;  2CFU A;  1MQO A;  5HH6 A;  2UYX A;  4HL1 A;  3I11 A;  3ZQ4 A;  2YNW A;  1VGN A;  2WYL A;  1BVT A;  5AHO A;  4C1H A;  4HKY A;  3IOG A;  2FK6 A;  2CFZ A;  4D1T A;  5HIP A;  3WXC A;  5AXR A;  4UAM A;  2Y8A A;  4TZ9 A;  3BK1 A;  3PG4 A;  5K4K A;  5AYA A;  4B87 A;  3S0Z A;  2BFK A;  4O98 A;  1A8T A;  2I7V A;  1KO3 A;  5LCH A;  3SW3 A;  2CG3 A;  3SRX A;  2BTN A;  3Q6V A;  5EVD A;  5FQC A;  4FEK A;  3IE2 A;  2YNU A;  5EV8 A;  2XR1 A;  4NQ4 A;  5KIL A;  4RM5 A;  4EYL A;  1XTO A;  2YZ3 A;  4F6H A;  3X30 A;  4YSL A;  2YNT A;  2ZNB A;  4KEQ A;  4NQ6 A;  5K4M A;  4WD6 A;  5A0T A;  1DXK A;  3F9O A;  3I13 A;  1JJE A;  4AX1 B;  3ZWF A;  5IQK A;  2BFZ A;  1BC2 A;  3ESH A;  2BG8 B;  2I7T A;  4PVO A;  2BIB A;  3PY6 A;  3AJ3 A;  2QIN A;  5FQB A;  2Y87 A;  4AX0 B;  3IE1 A;  2NYP A;  3RKK A;  3ADR A;  5ACS A;  4J5H A;  2OHI A;  1JT1 A;  3RKJ A;  4RBS A;  2M5D A;  4YSK A;  4RAM A;  2P18 A;  2BR6 A;  5EVB A;  3ZR9 A;  3PY5 A;  2A7M A;  2OHJ A;  1QH5 A;  4YSB A;  4RAW A;  3DHB A;  5HIS A;  5LCA A;  4NUR A;  2FU6 A;  4AV7 A;  4XWT A;  3X2Y A;  1YCG A;  5EV6 A;  4EYB A;  4C1G A;  4TZE A;  2FM6 A;  3X2X A;  4Z60 A;  2FHX A;  4C1F A;  2CBN A;  4C1E A;  4C09 A;  4DIL A;  4D02 A;  1X8I A;  4ZO2 A;  3FCZ A;  3SPU A;  4AWY B;  2OHH A;  5LM6 A;  5K4N A;  2AIO A;  2GCU A;  2DOO A;  2BG6 A;  4TYT A;  2BMI A;  4Z7R A;  3VPE A;  2BC2 A;  5AIJ A;  2YHE A;  5EH9 A;  5HH5 A;  3X2Z A;  5EW0 A;  4Z67 A;  2FU7 A;  4J5F A;  2NZE A;  1HLK A;  3KNR A;  5LE1 A;  3FAI A;  2FU8 A;  1L9Y A;  1ZNB A;  1ZTC A;  3MD7 A;  1A7T A;  1BMC A;  1WRA A;  1DDK A;  5ACR A;  3VQZ A;  3I14 A;  3AF6 A;  1X8H A;  5ACW A;  2I7X A;  5AXO A;  2WHG A;  4EY2 A;  3JXP A;  2XF4 A;  3IEM A;  4TZF A;  4H0D A;  5ACP A;  4KEP A;  5AEB A;  4D1V A;  2BFZ B;  4EFZ A;  4HL2 A;  3I15 A;  4GYU A;  2WYM C;  2AZ4 A;  2QDS A;  2ZWR A;  2ZO4 A;  4FSB A;  4RL0 A;  2GFJ A;  4AXH A;  2E7Y A;  5DPX A;  1WUP A;  1YCH A;  1KR3 A;  1XM8 A;  3RPC A;  2BG8 A;  5A23 A;  3SD9 A;  4C1D A;  4U4L A;  1M2X A;  4EXY A;  2R2D A;  4Z6X A;  5B15 A;  4GCW A;  3IOF A;  4PVT A;  3ZNB A;  2ZZI A;  1X8G A;  2VW8 A;  2YNV B;  3T3N A;  5EWA A;  2Q9U A;  3BK2 A;  5EVK A;  1SML A;  1Y44 A;  4FR7 A;  2NZF A;  2BFL A;  4NQ2 A;  1WW1 A;  2P97 A;  5K0W A;  1E5D A;  5A5Z A;  4XWW A;  4Z5Z A;  2P4Z A;  4BZ3 A;  5HIO A;  2P1E A;  2H6A A;  4JO0 A;  3IDZ A;  4XUK A;  4LE6 A;  2BGA A;  1DD6 A;  1VME A;  2FU9 A;  4ZEJ A;  2Q42 A;  2Y8B A;  1K07 A;  3H3E A;  3LVZ A;  4AD9 A;  4D1U A;  5AHR A;  4UWP B; 
#chains in the Genus database with same CATH homology
 5LCF A;  4Z5Y A;  4UWO B;  3DH8 A;  4V0H A;  1VJN A;  1WUO A;  4UA4 A;  4EYF A;  2M5C A;  2YNT B;  2YCB A;  5ACU A;  3R2U A;  4EXS A;  4NQ5 A;  3BV6 A;  3L6N A;  4UWS B;  4DIK A;  4ZNB A;  4ZO3 A;  3T3O A;  3A4Y A;  4P62 A;  3I0V A;  2BG2 A;  4F6Z A;  3BC2 A;  4AWZ A;  4D1W A;  5ACQ A;  2Q0J A;  3DHA A;  2QJS A;  2BG7 A;  3DHC A;  5FQA A;  3P2U A;  4TZB A;  1JJT A;  2DKF A;  4CHL A;  3KNS A;  3T9M A;  5A0V A;  5EHT A;  5HH4 A;  5ACV A;  1ZKP A;  3IEK A;  2WRS A;  3IE0 A;  4UWR B;  3QH8 A;  5LSC A;  4TYF A;  1KO2 A;  5A87 A;  4C1C A;  3SFP A;  2QED A;  2Q0I A;  2GMN A;  3AF5 A;  1P9E A;  2QDT A;  5B1U A;  4UBQ A;  3G1P A;  4BP0 A;  5LLD A;  5B3R A;  2GKL A;  5HIQ A;  4RL2 A;  3SBL A;  5ACT A;  2WYM A;  1YCF A;  3KL7 A;  2HB9 A;  5ACX A;  5LS3 A;  1QH3 A;  3TP9 A;  2FHX B;  5LMC A;  3IEL A;  2NXA A;  2YNV A;  2GFK A;  5KIK A;  4GYQ A;  1MQO A;  5HH6 A;  2UYX A;  4HL1 A;  3I11 A;  3ZQ4 A;  2YNW A;  1VGN A;  2WYL A;  1BVT A;  5AHO A;  4C1H A;  4HKY A;  3IOG A;  2FK6 A;  4D1T A;  5HIP A;  3WXC A;  5AXR A;  4UAM A;  2Y8A A;  4TZ9 A;  3BK1 A;  3PG4 A;  5K4K A;  5AYA A;  4B87 A;  3S0Z A;  2BFK A;  4O98 A;  1A8T A;  2I7V A;  1KO3 A;  5LCH A;  3SW3 A;  3SRX A;  2BTN A;  3Q6V A;  5EVD A;  5FQC A;  4FEK A;  3IE2 A;  2YNU A;  5EV8 A;  2XR1 A;  4NQ4 A;  5KIL A;  4RM5 A;  4EYL A;  1XTO A;  2YZ3 A;  4F6H A;  3X30 A;  4YSL A;  2YNT A;  2ZNB A;  4KEQ A;  4NQ6 A;  5K4M A;  4WD6 A;  5A0T A;  1DXK A;  3F9O A;  3I13 A;  1JJE A;  4AX1 B;  3ZWF A;  5IQK A;  2BFZ A;  1BC2 A;  3ESH A;  2BG8 B;  2I7T A;  4PVO A;  2BIB A;  3PY6 A;  3AJ3 A;  2QIN A;  5FQB A;  2Y87 A;  4AX0 B;  3IE1 A;  2NYP A;  3RKK A;  3ADR A;  5ACS A;  4J5H A;  2OHI A;  1JT1 A;  3RKJ A;  4RBS A;  2M5D A;  4YSK A;  4RAM A;  2P18 A;  2BR6 A;  5EVB A;  3ZR9 A;  3PY5 A;  2A7M A;  2OHJ A;  1QH5 A;  4YSB A;  4RAW A;  3DHB A;  5HIS A;  5LCA A;  2FU6 A;  4XWT A;  3X2Y A;  1YCG A;  5EV6 A;  4EYB A;  4C1G A;  4TZE A;  2FM6 A;  3X2X A;  4Z60 A;  2FHX A;  4C1F A;  2CBN A;  4C1E A;  4C09 A;  4DIL A;  4D02 A;  1X8I A;  4ZO2 A;  3FCZ A;  3SPU A;  4AWY B;  2OHH A;  5LM6 A;  5K4N A;  2AIO A;  2GCU A;  2DOO A;  2BG6 A;  4TYT A;  2BMI A;  4Z7R A;  3VPE A;  2BC2 A;  5EH9 A;  5HH5 A;  3X2Z A;  5EW0 A;  4Z67 A;  2FU7 A;  4J5F A;  2NZE A;  1HLK A;  3KNR A;  5LE1 A;  3FAI A;  2FU8 A;  1L9Y A;  1ZNB A;  1ZTC A;  3MD7 A;  1A7T A;  1BMC A;  1WRA A;  1DDK A;  5ACR A;  3VQZ A;  3I14 A;  3AF6 A;  1X8H A;  5ACW A;  2I7X A;  5AXO A;  2WHG A;  4EY2 A;  3JXP A;  2XF4 A;  3IEM A;  4TZF A;  4H0D A;  5ACP A;  4KEP A;  5AEB A;  4D1V A;  2BFZ B;  4EFZ A;  4HL2 A;  3I15 A;  4GYU A;  2WYM C;  2AZ4 A;  2QDS A;  2ZWR A;  2ZO4 A;  4FSB A;  4RL0 A;  2GFJ A;  2E7Y A;  5DPX A;  1WUP A;  1YCH A;  1KR3 A;  1XM8 A;  3RPC A;  2BG8 A;  3SD9 A;  4C1D A;  4U4L A;  1M2X A;  4EXY A;  2R2D A;  4Z6X A;  5B15 A;  4GCW A;  3IOF A;  4PVT A;  3ZNB A;  2ZZI A;  1X8G A;  2VW8 A;  2YNV B;  3T3N A;  5EWA A;  2Q9U A;  3BK2 A;  5EVK A;  1SML A;  1Y44 A;  4FR7 A;  2NZF A;  2BFL A;  4NQ2 A;  1WW1 A;  2P97 A;  5K0W A;  1E5D A;  5A5Z A;  4XWW A;  4Z5Z A;  2P4Z A;  4BZ3 A;  5HIO A;  2P1E A;  2H6A A;  4JO0 A;  3IDZ A;  4XUK A;  4LE6 A;  2BGA A;  1DD6 A;  1VME A;  2FU9 A;  4ZEJ A;  2Q42 A;  2Y8B A;  1K07 A;  3H3E A;  3LVZ A;  4AD9 A;  4D1U A;  5AHR A;  4UWP B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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