5K4NA

Directed evolutionary changes in mbl super family - ndm-1 round 10 crystal-2
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
228
structure length
228
Chain Sequence
DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Enzyme evolvability is contingent on the initial sequence background
rcsb
molecule tags Hydrolase
source organism Klebsiella pneumoniae
molecule keywords Metallo-beta-lactamase type 2
total genus 75
structure length 228
sequence length 228
ec nomenclature
pdb deposition date 2016-05-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5k4nA00
4TZ9A 2BG8B 2WYMA 4Z6XA 2GKLA 1X8HA 5FQAA 5FQCA 3PY5A 5ACXA 3DHAA 4AWZA 3ADRA 3IEMA 4Z5YA 2Y87A 5HH4A 4BP0A 1WUPA 4YSBA 2I7VA 4Z67A 2BFZB 2BG2A 3R2UA 3ZWFA 4ZO2A 5LCAA 1WUOA 4D1VA 3T3NA 5ACWA 4C1FA 5ACTA 5HISA 5K0WA 1VMEA 4V0HA 5HIQA 3QH8A 2FK6A 4CHLA 3ZNBA 2ZNBA 2FHXB 3IE1A 5A0TA 3I14A 3IELA 2P1EA 2NZEA 3DH8A 1A7TA 2A7MA 4UWOB 4AWYB 3DHBA 4UWSB 2FU7A 3SD9A 2QINA 4ZEJA 2R2DA 2FM6A 3LVZA 2FU8A 4XWWA 5LMCA 2OHIA 4Z60A 3G1PA 2YNTA 5EH9A 4ZO3A 1X8GA 2BC2A 5AXOA 1L9YA 2BG8A 4FSBA 3SFPA 4Z5ZA 4NQ5A 1DDKA 2WYMC 4YSKA 5AXRA 2QEDA 3IE2A 2Q9UA 4AX1B 4GYUA 4AX0B 5EV6A 5B1UA 4RAMA 5B15A 2DOOA 4F6HA 2XR1A 4KEPA 4F6ZA 5DPXA 1X8IA 1JJTA 3Q6VA 4J5HA 2BR6A 1KO2A 1VGNA 4RL0A 1DD6A 3X2ZA 5LCHA 3H3EA 2BG7A 3IE0A 3JXPA 2BFZA 4DILA 4WD6A 5AEBA 3BK2A 4O98A 5ACQA 4C1GA 1WW1A 2P97A 2AIOA 1QH3A 4XWTA 3T9MA 2FHXA 1ZTCA 5EHTA 5HH5A 3ZQ4A 5IQKA 2FU9A 4RL2A 2GFKA 4UAMA 3WXCA 3AF6A 4TZEA 4B87A 2OHHA 4P62A 5HH6A 2E7YA 1WRAA 4ZNBA 2QJSA 2Y8BA 2DKFA 2M5DA 3AF5A 3ZR9A 4C1DA 1E5DA 4D1TA 3T3OA 2ZWRA 3TP9A 3KNSA 2GFJA 3I0VA 1YCGA 4LE6A 3I15A 3FAIA 3IDZA 5A0VA 5ACVA 4TYFA 4EXSA 5AYAA 1BVTA 2OHJA 4YSLA 4FR7A 1MQOA 2GMNA 1KO3A 2UYXA 2P4ZA 3P2UA 2YNUA 4NQ6A 4XUKA 4EYBA 4KEQA 5A87A 5EV8A 2YNVB 5ACSA 5AHRA 4C1EA 1M2XA 5A5ZA 1KR3A 1BC2A 4AD9A 2VW8A 5LSCA 2FU6A 1P9EA 3BC2A 1JJEA 2GCUA 2ZZIA 2I7XA 2YCBA 2BFKA 3SRXA 1ZNBA 5LLDA 4FEKA 2NXAA 2AZ4A 4NQ2A 3DHCA 3ESHA 4H0DA 5HIOA 4UWPB 3BK1A 4UWRB 2ZO4A 4RAWA 4J5FA 4D1UA 4HL2A 1JT1A 2Q42A 5ACRA 4EYLA 2BTNA 4TZBA 4C1CA 3KL7A 1QH5A 2YZ3A 5EVKA 3VPEA 2BMIA 2BIBA 2QDTA 5EWAA 1DXKA 5LM6A 3VQZA 1A8TA 1BMCA 5ACPA 2QDSA 4RBSA 4HKYA 4NQ4A 4D1WA 4EYFA 3FCZA 2WYLA 3RKJA 3KNRA 4C1HA 4EFZA 3SW3A 3I11A 5ACUA 5EVBA 2YNVA 5B3RA 4GCWA 3RKKA 5KIKA 3L6NA 4UA4A 1Y44A 4UBQA 5K4MA 4DIKA 3IOGA 3A4YA 5K4KA 4D02A 3IOFA 5LCFA 5AHOA 4EXYA 4U4LA 5FQBA 4HL1A 5EVDA 3SPUA 3IEKA 2P18A 2NYPA 2Y8AA 4TZFA 4PVTA 5K4NA 1YCFA 2HB9A 2BGAA 2WRSA 3SBLA 3PY6A 2YNWA 2H6AA 3X30A 2XF4A 3BV6A 5LS3A 3RPCA 5KILA 5HIPA 1ZKPA 2Q0IA 4BZ3A 4GYQA 5EW0A 4TYTA 3MD7A 3AJ3A 4Z7RA 1XM8A 5LE1A 2WHGA 1SMLA 4EY2A 1K07A 2Q0JA 3PG4A 4C09A 3X2XA 4RM5A 2CBNA 3S0ZA 2NZFA 3F9OA 4PVOA 3X2YA 4JO0A 1XTOA 1YCHA 2M5CA 1HLKA 1VJNA 2I7TA 2BFLA 2YNTB 3I13A 2BG6A
chains in the Genus database with same CATH superfamily
4TZ9A 2BG8B 2WYMA 4Z6XA 2GKLA 1X8HA 5FQAA 5FQCA 3PY5A 5ACXA 3DHAA 4AWZA 3ADRA 3IEMA 4Z5YA 2Y87A 5HH4A 4BP0A 1WUPA 4YSBA 2I7VA 4PDXA 4Z67A 2BFZB 2BG2A 3R2UA 3ZWFA 4ZO2A 5LCAA 1WUOA 4D1VA 3T3NA 5ACWA 4C1FA 5ACTA 5HISA 5K0WA 1VMEA 4V0HA 5HIQA 3QH8A 2FK6A 4CHLA 3ZNBA 2ZNBA 2FHXB 3IE1A 5A0TA 3I14A 3IELA 2P1EA 2NZEA 3DH8A 1A7TA 2A7MA 4UWOB 4AWYB 3DHBA 4UWSB 2FU7A 3SD9A 2QINA 4ZEJA 2R2DA 2FM6A 3LVZA 2FU8A 4XWWA 5LMCA 2OHIA 4Z60A 3G1PA 2YNTA 5EH9A 4ZO3A 1X8GA 2BC2A 5AXOA 1L9YA 2BG8A 4FSBA 3SFPA 4Z5ZA 4NQ5A 1DDKA 2WYMC 4YSKA 5AXRA 2QEDA 3IE2A 2Q9UA 4AX1B 4GYUA 4AX0B 5EV6A 5B1UA 4RAMA 5B15A 2DOOA 4F6HA 2XR1A 4KEPA 4F6ZA 5DPXA 1X8IA 1JJTA 3Q6VA 4J5HA 2BR6A 1KO2A 2CG3A 1VGNA 4RL0A 1DD6A 3X2ZA 5LCHA 3H3EA 2BG7A 3IE0A 3JXPA 2BFZA 4DILA 4WD6A 5AEBA 3BK2A 4O98A 5ACQA 4C1GA 1WW1A 2P97A 2AIOA 1QH3A 4XWTA 3T9MA 2FHXA 1ZTCA 5EHTA 5HH5A 3ZQ4A 5IQKA 2FU9A 4RL2A 2GFKA 4UAMA 3WXCA 3AF6A 4TZEA 4B87A 2OHHA 4P62A 5HH6A 2E7YA 1WRAA 4ZNBA 2QJSA 2Y8BA 2DKFA 2M5DA 3AF5A 3ZR9A 4C1DA 1E5DA 4D1TA 3T3OA 2ZWRA 3TP9A 3KNSA 2GFJA 3I0VA 1YCGA 4LE6A 3I15A 3FAIA 3IDZA 5A0VA 5ACVA 4TYFA 4EXSA 5AYAA 1BVTA 2OHJA 4YSLA 4FR7A 4NURA 1MQOA 2GMNA 1KO3A 2UYXA 2P4ZA 2CG2A 3P2UA 2YNUA 4NQ6A 4XUKA 4EYBA 4KEQA 5A87A 5EV8A 5AIJA 2YNVB 5ACSA 5AHRA 4C1EA 1M2XA 5A5ZA 1KR3A 1BC2A 4AD9A 2VW8A 5LSCA 2FU6A 1P9EA 3BC2A 1JJEA 2GCUA 2ZZIA 2I7XA 2YCBA 2BFKA 3SRXA 1ZNBA 5LLDA 4FEKA 2NXAA 2AZ4A 4NQ2A 3DHCA 2CFZA 3ESHA 4H0DA 5HIOA 4UWPB 3BK1A 4UWRB 2ZO4A 4RAWA 4J5FA 4D1UA 4HL2A 1JT1A 2Q42A 5ACRA 4EYLA 2BTNA 4TZBA 4C1CA 2YHEA 3KL7A 1QH5A 2YZ3A 5EVKA 3VPEA 2BMIA 2BIBA 2QDTA 5EWAA 1DXKA 5LM6A 3VQZA 1A8TA 1BMCA 5ACPA 2QDSA 5AJLA 4RBSA 4HKYA 4NQ4A 4D1WA 4EYFA 3FCZA 2WYLA 3RKJA 3KNRA 4C1HA 4EFZA 3SW3A 3I11A 5ACUA 5EVBA 2YNVA 5B3RA 4GCWA 3RKKA 5KIKA 3L6NA 4UA4A 1Y44A 4UBQA 5K4MA 4DIKA 4AXHA 3IOGA 3A4YA 5K4KA 4D02A 3IOFA 5LCFA 5AHOA 4EXYA 4U4LA 5FQBA 4HL1A 5EVDA 3SPUA 3IEKA 2P18A 2NYPA 2Y8AA 4TZFA 4PVTA 5K4NA 1YCFA 2HB9A 2BGAA 2WRSA 3SBLA 4AV7A 3PY6A 2YNWA 2H6AA 3X30A 2XF4A 3BV6A 5LS3A 3RPCA 5KILA 5HIPA 1ZKPA 2Q0IA 4BZ3A 4GYQA 5EW0A 4TYTA 3MD7A 3AJ3A 4Z7RA 1XM8A 5LE1A 2WHGA 1SMLA 4EY2A 1K07A 2Q0JA 3PG4A 4C09A 3X2XA 4RM5A 2CBNA 3S0ZA 2NZFA 3F9OA 4PVOA 3X2YA 2CFUA 4JO0A 1XTOA 1YCHA 2M5CA 1HLKA 1VJNA 2I7TA 2BFLA 5A23A 2YNTB 3I13A 2BG6A
chains in the Genus database with same CATH topology
4TZ9A 2BG8B 2WYMA 4Z6XA 2GKLA 1X8HA 5FQAA 5FQCA 3PY5A 5ACXA 3DHAA 4AWZA 3ADRA 3IEMA 4Z5YA 2Y87A 5HH4A 4BP0A 1WUPA 4YSBA 2I7VA 4Z67A 2BFZB 2BG2A 3R2UA 3ZWFA 4ZO2A 5LCAA 1WUOA 4D1VA 3T3NA 5ACWA 4C1FA 5ACTA 5HISA 5K0WA 1VMEA 4V0HA 5HIQA 3QH8A 2FK6A 4CHLA 3ZNBA 2ZNBA 2FHXB 3IE1A 5A0TA 3I14A 3IELA 2P1EA 2NZEA 3DH8A 1A7TA 2A7MA 4UWOB 4AWYB 3DHBA 4UWSB 2FU7A 3SD9A 2QINA 4ZEJA 2R2DA 2FM6A 3LVZA 2FU8A 4XWWA 5LMCA 2OHIA 4Z60A 3G1PA 2YNTA 5EH9A 4ZO3A 1X8GA 2BC2A 5AXOA 1L9YA 2BG8A 4FSBA 3SFPA 4Z5ZA 4NQ5A 1DDKA 2WYMC 4YSKA 5AXRA 2QEDA 3IE2A 2Q9UA 4AX1B 4GYUA 4AX0B 5EV6A 5B1UA 4RAMA 5B15A 2DOOA 4F6HA 2XR1A 4KEPA 4F6ZA 5DPXA 1X8IA 1JJTA 3Q6VA 4J5HA 2BR6A 1KO2A 1VGNA 4RL0A 1DD6A 3X2ZA 5LCHA 3H3EA 2BG7A 3IE0A 3JXPA 2BFZA 4DILA 4WD6A 5AEBA 3BK2A 4O98A 5ACQA 4C1GA 1WW1A 2P97A 2AIOA 1QH3A 4XWTA 3T9MA 2FHXA 1ZTCA 5EHTA 5HH5A 3ZQ4A 5IQKA 2FU9A 4RL2A 2GFKA 4UAMA 3WXCA 3AF6A 4TZEA 4B87A 2OHHA 4P62A 5HH6A 2E7YA 1WRAA 4ZNBA 2QJSA 2Y8BA 2DKFA 2M5DA 3AF5A 3ZR9A 4C1DA 1E5DA 4D1TA 3T3OA 2ZWRA 3TP9A 3KNSA 2GFJA 3I0VA 1YCGA 4LE6A 3I15A 3FAIA 3IDZA 5A0VA 5ACVA 4TYFA 4EXSA 5AYAA 1BVTA 2OHJA 4YSLA 4FR7A 1MQOA 2GMNA 1KO3A 2UYXA 2P4ZA 3P2UA 2YNUA 4NQ6A 4XUKA 4EYBA 4KEQA 5A87A 5EV8A 2YNVB 5ACSA 5AHRA 4C1EA 1M2XA 5A5ZA 1KR3A 1BC2A 4AD9A 2VW8A 5LSCA 2FU6A 1P9EA 3BC2A 1JJEA 2GCUA 2ZZIA 2I7XA 2YCBA 2BFKA 3SRXA 1ZNBA 5LLDA 4FEKA 2NXAA 2AZ4A 4NQ2A 3DHCA 3ESHA 4H0DA 5HIOA 4UWPB 3BK1A 4UWRB 2ZO4A 4RAWA 4J5FA 4D1UA 4HL2A 1JT1A 2Q42A 5ACRA 4EYLA 2BTNA 4TZBA 4C1CA 3KL7A 1QH5A 2YZ3A 5EVKA 3VPEA 2BMIA 2BIBA 2QDTA 5EWAA 1DXKA 5LM6A 3VQZA 1A8TA 1BMCA 5ACPA 2QDSA 4RBSA 4HKYA 4NQ4A 4D1WA 4EYFA 3FCZA 2WYLA 3RKJA 3KNRA 4C1HA 4EFZA 3SW3A 3I11A 5ACUA 5EVBA 2YNVA 5B3RA 4GCWA 3RKKA 5KIKA 3L6NA 4UA4A 1Y44A 4UBQA 5K4MA 4DIKA 3IOGA 3A4YA 5K4KA 4D02A 3IOFA 5LCFA 5AHOA 4EXYA 4U4LA 5FQBA 4HL1A 5EVDA 3SPUA 3IEKA 2P18A 2NYPA 2Y8AA 4TZFA 4PVTA 5K4NA 1YCFA 2HB9A 2BGAA 2WRSA 3SBLA 3PY6A 2YNWA 2H6AA 3X30A 2XF4A 3BV6A 5LS3A 3RPCA 5KILA 5HIPA 1ZKPA 2Q0IA 4BZ3A 4GYQA 5EW0A 4TYTA 3MD7A 3AJ3A 4Z7RA 1XM8A 5LE1A 2WHGA 1SMLA 4EY2A 1K07A 2Q0JA 3PG4A 4C09A 3X2XA 4RM5A 2CBNA 3S0ZA 2NZFA 3F9OA 4PVOA 3X2YA 4JO0A 1XTOA 1YCHA 2M5CA 1HLKA 1VJNA 2I7TA 2BFLA 2YNTB 3I13A 2BG6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4TZ9 A;  2BG8 B;  2WYM A;  4Z6X A;  2GKL A;  1X8H A;  5FQA A;  5FQC A;  3PY5 A;  5ACX A;  3DHA A;  4AWZ A;  3ADR A;  3IEM A;  4Z5Y A;  2Y87 A;  5HH4 A;  4BP0 A;  1WUP A;  4YSB A;  2I7V A;  4Z67 A;  2BFZ B;  2BG2 A;  3R2U A;  3ZWF A;  4ZO2 A;  5LCA A;  1WUO A;  4D1V A;  3T3N A;  5ACW A;  4C1F A;  5ACT A;  5HIS A;  5K0W A;  1VME A;  4V0H A;  5HIQ A;  3QH8 A;  2FK6 A;  4CHL A;  3ZNB A;  2ZNB A;  2FHX B;  3IE1 A;  5A0T A;  3I14 A;  3IEL A;  2P1E A;  2NZE A;  3DH8 A;  1A7T A;  2A7M A;  4UWO B;  4AWY B;  3DHB A;  4UWS B;  2FU7 A;  3SD9 A;  2QIN A;  4ZEJ A;  2R2D A;  2FM6 A;  3LVZ A;  2FU8 A;  4XWW A;  5LMC A;  2OHI A;  4Z60 A;  3G1P A;  2YNT A;  5EH9 A;  4ZO3 A;  1X8G A;  2BC2 A;  5AXO A;  1L9Y A;  2BG8 A;  4FSB A;  3SFP A;  4Z5Z A;  4NQ5 A;  1DDK A;  2WYM C;  4YSK A;  5AXR A;  2QED A;  3IE2 A;  2Q9U A;  4AX1 B;  4GYU A;  4AX0 B;  5EV6 A;  5B1U A;  4RAM A;  5B15 A;  2DOO A;  4F6H A;  2XR1 A;  4KEP A;  4F6Z A;  5DPX A;  1X8I A;  1JJT A;  3Q6V A;  4J5H A;  2BR6 A;  1KO2 A;  1VGN A;  4RL0 A;  1DD6 A;  3X2Z A;  5LCH A;  3H3E A;  2BG7 A;  3IE0 A;  3JXP A;  2BFZ A;  4DIL A;  4WD6 A;  5AEB A;  3BK2 A;  4O98 A;  5ACQ A;  4C1G A;  1WW1 A;  2P97 A;  2AIO A;  1QH3 A;  4XWT A;  3T9M A;  2FHX A;  1ZTC A;  5EHT A;  5HH5 A;  3ZQ4 A;  5IQK A;  2FU9 A;  4RL2 A;  2GFK A;  4UAM A;  3WXC A;  3AF6 A;  4TZE A;  4B87 A;  2OHH A;  4P62 A;  5HH6 A;  2E7Y A;  1WRA A;  4ZNB A;  2QJS A;  2Y8B A;  2DKF A;  2M5D A;  3AF5 A;  3ZR9 A;  4C1D A;  1E5D A;  4D1T A;  3T3O A;  2ZWR A;  3TP9 A;  3KNS A;  2GFJ A;  3I0V A;  1YCG A;  4LE6 A;  3I15 A;  3FAI A;  3IDZ A;  5A0V A;  5ACV A;  4TYF A;  4EXS A;  5AYA A;  1BVT A;  2OHJ A;  4YSL A;  4FR7 A;  1MQO A;  2GMN A;  1KO3 A;  2UYX A;  2P4Z A;  3P2U A;  2YNU A;  4NQ6 A;  4XUK A;  4EYB A;  4KEQ A;  5A87 A;  5EV8 A;  2YNV B;  5ACS A;  5AHR A;  4C1E A;  1M2X A;  5A5Z A;  1KR3 A;  1BC2 A;  4AD9 A;  2VW8 A;  5LSC A;  2FU6 A;  1P9E A;  3BC2 A;  1JJE A;  2GCU A;  2ZZI A;  2I7X A;  2YCB A;  2BFK A;  3SRX A;  1ZNB A;  5LLD A;  4FEK A;  2NXA A;  2AZ4 A;  4NQ2 A;  3DHC A;  3ESH A;  4H0D A;  5HIO A;  4UWP B;  3BK1 A;  4UWR B;  2ZO4 A;  4RAW A;  4J5F A;  4D1U A;  4HL2 A;  1JT1 A;  2Q42 A;  5ACR A;  4EYL A;  2BTN A;  4TZB A;  4C1C A;  3KL7 A;  1QH5 A;  2YZ3 A;  5EVK A;  3VPE A;  2BMI A;  2BIB A;  2QDT A;  5EWA A;  1DXK A;  5LM6 A;  3VQZ A;  1A8T A;  1BMC A;  5ACP A;  2QDS A;  4RBS A;  4HKY A;  4NQ4 A;  4D1W A;  4EYF A;  3FCZ A;  2WYL A;  3RKJ A;  3KNR A;  4C1H A;  4EFZ A;  3SW3 A;  3I11 A;  5ACU A;  5EVB A;  2YNV A;  5B3R A;  4GCW A;  3RKK A;  5KIK A;  3L6N A;  4UA4 A;  1Y44 A;  4UBQ A;  5K4M A;  4DIK A;  3IOG A;  3A4Y A;  5K4K A;  4D02 A;  3IOF A;  5LCF A;  5AHO A;  4EXY A;  4U4L A;  5FQB A;  4HL1 A;  5EVD A;  3SPU A;  3IEK A;  2P18 A;  2NYP A;  2Y8A A;  4TZF A;  4PVT A;  5K4N A;  1YCF A;  2HB9 A;  2BGA A;  2WRS A;  3SBL A;  3PY6 A;  2YNW A;  2H6A A;  3X30 A;  2XF4 A;  3BV6 A;  5LS3 A;  3RPC A;  5KIL A;  5HIP A;  1ZKP A;  2Q0I A;  4BZ3 A;  4GYQ A;  5EW0 A;  4TYT A;  3MD7 A;  3AJ3 A;  4Z7R A;  1XM8 A;  5LE1 A;  2WHG A;  1SML A;  4EY2 A;  1K07 A;  2Q0J A;  3PG4 A;  4C09 A;  3X2X A;  4RM5 A;  2CBN A;  3S0Z A;  2NZF A;  3F9O A;  4PVO A;  3X2Y A;  4JO0 A;  1XTO A;  1YCH A;  2M5C A;  1HLK A;  1VJN A;  2I7T A;  2BFL A;  2YNT B;  3I13 A;  2BG6 A; 
#chains in the Genus database with same CATH topology
 4TZ9 A;  2BG8 B;  2WYM A;  4Z6X A;  2GKL A;  1X8H A;  5FQA A;  5FQC A;  3PY5 A;  5ACX A;  3DHA A;  4AWZ A;  3ADR A;  3IEM A;  4Z5Y A;  2Y87 A;  5HH4 A;  4BP0 A;  1WUP A;  4YSB A;  2I7V A;  4PDX A;  4Z67 A;  2BFZ B;  2BG2 A;  3R2U A;  3ZWF A;  4ZO2 A;  5LCA A;  1WUO A;  4D1V A;  3T3N A;  5ACW A;  4C1F A;  5ACT A;  5HIS A;  5K0W A;  1VME A;  4V0H A;  5HIQ A;  3QH8 A;  2FK6 A;  4CHL A;  3ZNB A;  2ZNB A;  2FHX B;  3IE1 A;  5A0T A;  3I14 A;  3IEL A;  2P1E A;  2NZE A;  3DH8 A;  1A7T A;  2A7M A;  4UWO B;  4AWY B;  3DHB A;  4UWS B;  2FU7 A;  3SD9 A;  2QIN A;  4ZEJ A;  2R2D A;  2FM6 A;  3LVZ A;  2FU8 A;  4XWW A;  5LMC A;  2OHI A;  4Z60 A;  3G1P A;  2YNT A;  5EH9 A;  4ZO3 A;  1X8G A;  2BC2 A;  5AXO A;  1L9Y A;  2BG8 A;  4FSB A;  3SFP A;  4Z5Z A;  4NQ5 A;  1DDK A;  2WYM C;  4YSK A;  5AXR A;  2QED A;  3IE2 A;  2Q9U A;  4AX1 B;  4GYU A;  4AX0 B;  5EV6 A;  5B1U A;  4RAM A;  5B15 A;  2DOO A;  4F6H A;  2XR1 A;  4KEP A;  4F6Z A;  5DPX A;  1X8I A;  1JJT A;  3Q6V A;  4J5H A;  2BR6 A;  1KO2 A;  2CG3 A;  1VGN A;  4RL0 A;  1DD6 A;  3X2Z A;  5LCH A;  3H3E A;  2BG7 A;  3IE0 A;  3JXP A;  2BFZ A;  4DIL A;  4WD6 A;  5AEB A;  3BK2 A;  4O98 A;  5ACQ A;  4C1G A;  1WW1 A;  2P97 A;  2AIO A;  1QH3 A;  4XWT A;  3T9M A;  2FHX A;  1ZTC A;  5EHT A;  5HH5 A;  3ZQ4 A;  5IQK A;  2FU9 A;  4RL2 A;  2GFK A;  4UAM A;  3WXC A;  3AF6 A;  4TZE A;  4B87 A;  2OHH A;  4P62 A;  5HH6 A;  2E7Y A;  1WRA A;  4ZNB A;  2QJS A;  2Y8B A;  2DKF A;  2M5D A;  3AF5 A;  3ZR9 A;  4C1D A;  1E5D A;  4D1T A;  3T3O A;  2ZWR A;  3TP9 A;  3KNS A;  2GFJ A;  3I0V A;  1YCG A;  4LE6 A;  3I15 A;  3FAI A;  3IDZ A;  5A0V A;  5ACV A;  4TYF A;  4EXS A;  5AYA A;  1BVT A;  2OHJ A;  4YSL A;  4FR7 A;  4NUR A;  1MQO A;  2GMN A;  1KO3 A;  2UYX A;  2P4Z A;  2CG2 A;  3P2U A;  2YNU A;  4NQ6 A;  4XUK A;  4EYB A;  4KEQ A;  5A87 A;  5EV8 A;  5AIJ A;  2YNV B;  5ACS A;  5AHR A;  4C1E A;  1M2X A;  5A5Z A;  1KR3 A;  1BC2 A;  4AD9 A;  2VW8 A;  5LSC A;  2FU6 A;  1P9E A;  3BC2 A;  1JJE A;  2GCU A;  2ZZI A;  2I7X A;  2YCB A;  2BFK A;  3SRX A;  1ZNB A;  5LLD A;  4FEK A;  2NXA A;  2AZ4 A;  4NQ2 A;  3DHC A;  2CFZ A;  3ESH A;  4H0D A;  5HIO A;  4UWP B;  3BK1 A;  4UWR B;  2ZO4 A;  4RAW A;  4J5F A;  4D1U A;  4HL2 A;  1JT1 A;  2Q42 A;  5ACR A;  4EYL A;  2BTN A;  4TZB A;  4C1C A;  2YHE A;  3KL7 A;  1QH5 A;  2YZ3 A;  5EVK A;  3VPE A;  2BMI A;  2BIB A;  2QDT A;  5EWA A;  1DXK A;  5LM6 A;  3VQZ A;  1A8T A;  1BMC A;  5ACP A;  2QDS A;  5AJL A;  4RBS A;  4HKY A;  4NQ4 A;  4D1W A;  4EYF A;  3FCZ A;  2WYL A;  3RKJ A;  3KNR A;  4C1H A;  4EFZ A;  3SW3 A;  3I11 A;  5ACU A;  5EVB A;  2YNV A;  5B3R A;  4GCW A;  3RKK A;  5KIK A;  3L6N A;  4UA4 A;  1Y44 A;  4UBQ A;  5K4M A;  4DIK A;  4AXH A;  3IOG A;  3A4Y A;  5K4K A;  4D02 A;  3IOF A;  5LCF A;  5AHO A;  4EXY A;  4U4L A;  5FQB A;  4HL1 A;  5EVD A;  3SPU A;  3IEK A;  2P18 A;  2NYP A;  2Y8A A;  4TZF A;  4PVT A;  5K4N A;  1YCF A;  2HB9 A;  2BGA A;  2WRS A;  3SBL A;  4AV7 A;  3PY6 A;  2YNW A;  2H6A A;  3X30 A;  2XF4 A;  3BV6 A;  5LS3 A;  3RPC A;  5KIL A;  5HIP A;  1ZKP A;  2Q0I A;  4BZ3 A;  4GYQ A;  5EW0 A;  4TYT A;  3MD7 A;  3AJ3 A;  4Z7R A;  1XM8 A;  5LE1 A;  2WHG A;  1SML A;  4EY2 A;  1K07 A;  2Q0J A;  3PG4 A;  4C09 A;  3X2X A;  4RM5 A;  2CBN A;  3S0Z A;  2NZF A;  3F9O A;  4PVO A;  3X2Y A;  2CFU A;  4JO0 A;  1XTO A;  1YCH A;  2M5C A;  1HLK A;  1VJN A;  2I7T A;  2BFL A;  5A23 A;  2YNT B;  3I13 A;  2BG6 A; 
#chains in the Genus database with same CATH homology
 4TZ9 A;  2BG8 B;  2WYM A;  4Z6X A;  2GKL A;  1X8H A;  5FQA A;  5FQC A;  3PY5 A;  5ACX A;  3DHA A;  4AWZ A;  3ADR A;  3IEM A;  4Z5Y A;  2Y87 A;  5HH4 A;  4BP0 A;  1WUP A;  4YSB A;  2I7V A;  4Z67 A;  2BFZ B;  2BG2 A;  3R2U A;  3ZWF A;  4ZO2 A;  5LCA A;  1WUO A;  4D1V A;  3T3N A;  5ACW A;  4C1F A;  5ACT A;  5HIS A;  5K0W A;  1VME A;  4V0H A;  5HIQ A;  3QH8 A;  2FK6 A;  4CHL A;  3ZNB A;  2ZNB A;  2FHX B;  3IE1 A;  5A0T A;  3I14 A;  3IEL A;  2P1E A;  2NZE A;  3DH8 A;  1A7T A;  2A7M A;  4UWO B;  4AWY B;  3DHB A;  4UWS B;  2FU7 A;  3SD9 A;  2QIN A;  4ZEJ A;  2R2D A;  2FM6 A;  3LVZ A;  2FU8 A;  4XWW A;  5LMC A;  2OHI A;  4Z60 A;  3G1P A;  2YNT A;  5EH9 A;  4ZO3 A;  1X8G A;  2BC2 A;  5AXO A;  1L9Y A;  2BG8 A;  4FSB A;  3SFP A;  4Z5Z A;  4NQ5 A;  1DDK A;  2WYM C;  4YSK A;  5AXR A;  2QED A;  3IE2 A;  2Q9U A;  4AX1 B;  4GYU A;  4AX0 B;  5EV6 A;  5B1U A;  4RAM A;  5B15 A;  2DOO A;  4F6H A;  2XR1 A;  4KEP A;  4F6Z A;  5DPX A;  1X8I A;  1JJT A;  3Q6V A;  4J5H A;  2BR6 A;  1KO2 A;  1VGN A;  4RL0 A;  1DD6 A;  3X2Z A;  5LCH A;  3H3E A;  2BG7 A;  3IE0 A;  3JXP A;  2BFZ A;  4DIL A;  4WD6 A;  5AEB A;  3BK2 A;  4O98 A;  5ACQ A;  4C1G A;  1WW1 A;  2P97 A;  2AIO A;  1QH3 A;  4XWT A;  3T9M A;  2FHX A;  1ZTC A;  5EHT A;  5HH5 A;  3ZQ4 A;  5IQK A;  2FU9 A;  4RL2 A;  2GFK A;  4UAM A;  3WXC A;  3AF6 A;  4TZE A;  4B87 A;  2OHH A;  4P62 A;  5HH6 A;  2E7Y A;  1WRA A;  4ZNB A;  2QJS A;  2Y8B A;  2DKF A;  2M5D A;  3AF5 A;  3ZR9 A;  4C1D A;  1E5D A;  4D1T A;  3T3O A;  2ZWR A;  3TP9 A;  3KNS A;  2GFJ A;  3I0V A;  1YCG A;  4LE6 A;  3I15 A;  3FAI A;  3IDZ A;  5A0V A;  5ACV A;  4TYF A;  4EXS A;  5AYA A;  1BVT A;  2OHJ A;  4YSL A;  4FR7 A;  1MQO A;  2GMN A;  1KO3 A;  2UYX A;  2P4Z A;  3P2U A;  2YNU A;  4NQ6 A;  4XUK A;  4EYB A;  4KEQ A;  5A87 A;  5EV8 A;  2YNV B;  5ACS A;  5AHR A;  4C1E A;  1M2X A;  5A5Z A;  1KR3 A;  1BC2 A;  4AD9 A;  2VW8 A;  5LSC A;  2FU6 A;  1P9E A;  3BC2 A;  1JJE A;  2GCU A;  2ZZI A;  2I7X A;  2YCB A;  2BFK A;  3SRX A;  1ZNB A;  5LLD A;  4FEK A;  2NXA A;  2AZ4 A;  4NQ2 A;  3DHC A;  3ESH A;  4H0D A;  5HIO A;  4UWP B;  3BK1 A;  4UWR B;  2ZO4 A;  4RAW A;  4J5F A;  4D1U A;  4HL2 A;  1JT1 A;  2Q42 A;  5ACR A;  4EYL A;  2BTN A;  4TZB A;  4C1C A;  3KL7 A;  1QH5 A;  2YZ3 A;  5EVK A;  3VPE A;  2BMI A;  2BIB A;  2QDT A;  5EWA A;  1DXK A;  5LM6 A;  3VQZ A;  1A8T A;  1BMC A;  5ACP A;  2QDS A;  4RBS A;  4HKY A;  4NQ4 A;  4D1W A;  4EYF A;  3FCZ A;  2WYL A;  3RKJ A;  3KNR A;  4C1H A;  4EFZ A;  3SW3 A;  3I11 A;  5ACU A;  5EVB A;  2YNV A;  5B3R A;  4GCW A;  3RKK A;  5KIK A;  3L6N A;  4UA4 A;  1Y44 A;  4UBQ A;  5K4M A;  4DIK A;  3IOG A;  3A4Y A;  5K4K A;  4D02 A;  3IOF A;  5LCF A;  5AHO A;  4EXY A;  4U4L A;  5FQB A;  4HL1 A;  5EVD A;  3SPU A;  3IEK A;  2P18 A;  2NYP A;  2Y8A A;  4TZF A;  4PVT A;  5K4N A;  1YCF A;  2HB9 A;  2BGA A;  2WRS A;  3SBL A;  3PY6 A;  2YNW A;  2H6A A;  3X30 A;  2XF4 A;  3BV6 A;  5LS3 A;  3RPC A;  5KIL A;  5HIP A;  1ZKP A;  2Q0I A;  4BZ3 A;  4GYQ A;  5EW0 A;  4TYT A;  3MD7 A;  3AJ3 A;  4Z7R A;  1XM8 A;  5LE1 A;  2WHG A;  1SML A;  4EY2 A;  1K07 A;  2Q0J A;  3PG4 A;  4C09 A;  3X2X A;  4RM5 A;  2CBN A;  3S0Z A;  2NZF A;  3F9O A;  4PVO A;  3X2Y A;  4JO0 A;  1XTO A;  1YCH A;  2M5C A;  1HLK A;  1VJN A;  2I7T A;  2BFL A;  2YNT B;  3I13 A;  2BG6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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