5LCHA

Vim-2 metallo-beta-lactamase in complex with (s)-1-allyl-2-(3-methoxyphenyl)-3-oxoisoindoline-4-carboxylic acid (compound 42)
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
230
structure length
230
Chain Sequence
b'YPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Metallo-beta-lactamase VIM-2
publication title NMR-filtered virtual screening leads to non-metal chelating metallo-beta-lactamase inhibitors.
pubmed doi rcsb
source organism Pseudomonas aeruginosa
molecule tags Hydrolase
total genus 72
structure length 230
sequence length 230
ec nomenclature
pdb deposition date 2016-06-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5lchA00
2DOOA 3DH8A 3X2YA 3X2XA 1P9EA 1WUPA 4EY2A 5EVKA 2YNTA 4H0DA 1KO3A 3RPCA 4AD9A 4TZ9A 2YNWA 4F6ZA 3SW3A 2WRSA 4C1DA 5LLDA 1Y44A 4C1GA 1WW1A 3BV6A 4UWRB 2Y87A 1XM8A 2I7VA 2FHXB 4EYFA 2FU7A 2YZ3A 4EXSA 2GFJA 4GCWA 2QDTA 2XF4A 4RL0A 3VQZA 4UBQA 2ZWRA 5ACWA 2ZZIA 2BG2A 3SPUA 2GMNA 2WYMA 3DHBA 4F6HA 5A87A 3I15A 4D1TA 3FCZA 4C1EA 1QH3A 4CHLA 5K4KA 3IE0A 2P18A 4WD6A 4HL1A 5EV8A 1ZKPA 2ZNBA 2M5CA 4AWYB 4DIKA 2FU8A 3AJ3A 2P4ZA 3L6NA 3BC2A 2Q0IA 4UA4A 4EXYA 2QJSA 1L9YA 5AEBA 2WYMC 1YCGA 5HH4A 2OHIA 3ZR9A 2WYLA 5HIQA 5ACRA 3PY6A 3ESHA 2GKLA 2YNVB 2XR1A 4FSBA 2Y8BA 3H3EA 2GFKA 2Q9UA 4DILA 5EVBA 3IEKA 5AYAA 2P1EA 2FHXA 2BTNA 4LE6A 5LE1A 4XWTA 3F9OA 4TYFA 3X2ZA 4FR7A 3RKJA 5K4NA 3S0ZA 4U4LA 3R2UA 3TP9A 4D1UA 1QH5A 5EWAA 5KIKA 4NQ2A 4EYBA 4O98A 4Z6XA 1YCFA 2Q0JA 1BMCA 4ZNBA 2BIBA 4RL2A 4D1WA 4RM5A 5AHOA 5FQAA 4EYLA 2YNUA 5HIPA 4GYQA 3AF5A 1VJNA 5K0WA 1M2XA 2CBNA 2I7TA 5ACUA 4KEQA 4TZEA 3SRXA 4TZBA 2FK6A 4Z7RA 2OHJA 3MD7A 2ZO4A 4UWSB 2AZ4A 1X8GA 4YSKA 5EVDA 1WRAA 2YNVA 2I7XA 4TYTA 5B1UA 4UAMA 5DPXA 1E5DA 1K07A 3T3NA 5ACPA 4UWOB 4C09A 4RBSA 3IEMA 3KNSA 4ZO3A 2BFZB 5ACXA 2OHHA 5A0TA 2AIOA 3ZNBA 4RAWA 1ZTCA 3WXCA 5LS3A 4AWZA 4EFZA 3ZQ4A 5FQCA 2HB9A 2BG7A 2YCBA 5EV6A 5AHRA 3ADRA 5FQBA 3SD9A 3IOFA 1BVTA 5ACTA 3KNRA 2QDSA 4C1CA 1KR3A 3X30A 4PVTA 4B87A 3LVZA 4HKYA 4NQ5A 3PY5A 4YSLA 4UWPB 2M5DA 3P2UA 3SBLA 3AF6A 5LMCA 2BG8B 2GCUA 1JJEA 3RKKA 4AX1B 2BGAA 5LSCA 4PVOA 4D1VA 4XUKA 3IELA 3JXPA 4XWWA 2FM6A 4BZ3A 1VGNA 5K4MA 1A8TA 1DD6A 1MQOA 3DHAA 3ZWFA 4KEPA 3BK1A 2FU9A 2QINA 5EH9A 3BK2A 5HH6A 2BFZA 3I14A 3A4YA 4AX0B 4FEKA 3I13A 1VMEA 2BC2A 3VPEA 2DKFA 3PG4A 5LCAA 2Q42A 1JJTA 2R2DA 1ZNBA 2NZFA 3FAIA 5HH5A 2A7MA 3DHCA 1JT1A 4C1FA 5LM6A 2BG6A 5AXOA 5B15A 1SMLA 1X8HA 2NYPA 4ZO2A 2P97A 5ACQA 4JO0A 4YSBA 5B3RA 5KILA 2BG8A 2Y8AA 5HIOA 4HL2A 5AXRA 2FU6A 3IOGA 2BMIA 3I11A 4P62A 2YNTB 5HISA 2BFLA 4NQ4A 3SFPA 2H6AA 1HLKA 4Z60A 1XTOA 3IE2A 1KO2A 5EHTA 4C1HA 5IQKA 2BFKA 2UYXA 1A7TA 3IE1A 1YCHA 1WUOA 4GYUA 4NQ6A 5LCHA 5ACSA 4J5FA 5A5ZA 4D02A 2NZEA 4RAMA 2WHGA 3G1PA 5EW0A 3Q6VA 5ACVA 1X8IA 5LCFA 4ZEJA 2QEDA 5A0VA 3IDZA 3QH8A 3T3OA 1BC2A 1DDKA 4Z5YA 2VW8A 3I0VA 2NXAA 4J5HA 3KL7A 2E7YA 4TZFA 3T9MA 4V0HA 4BP0A 4Z67A 4Z5ZA 1DXKA 2BR6A
chains in the Genus database with same CATH superfamily
2DOOA 3DH8A 3X2YA 3X2XA 1P9EA 1WUPA 4EY2A 5EVKA 2YNTA 4H0DA 1KO3A 2CFZA 3RPCA 4AD9A 4TZ9A 2YNWA 4F6ZA 3SW3A 2WRSA 4C1DA 5LLDA 1Y44A 4C1GA 1WW1A 3BV6A 5AIJA 4NURA 2Y87A 4UWRB 1XM8A 2I7VA 2FHXB 4EYFA 2FU7A 2YZ3A 4EXSA 2GFJA 4GCWA 2QDTA 2CG3A 2XF4A 4RL0A 3VQZA 4UBQA 2ZWRA 5ACWA 2ZZIA 2BG2A 3SPUA 2GMNA 2WYMA 3DHBA 4F6HA 5A87A 3I15A 4D1TA 3FCZA 4C1EA 1QH3A 2YHEA 4CHLA 5K4KA 3IE0A 2P18A 4WD6A 4HL1A 5EV8A 1ZKPA 2ZNBA 2M5CA 4AWYB 4DIKA 2FU8A 3AJ3A 2P4ZA 3L6NA 3BC2A 2Q0IA 4UA4A 4EXYA 2QJSA 1L9YA 5AEBA 2WYMC 1YCGA 5HH4A 2OHIA 3ZR9A 2WYLA 5HIQA 5ACRA 3PY6A 3ESHA 2GKLA 2YNVB 2XR1A 4FSBA 2Y8BA 3H3EA 2GFKA 2Q9UA 4DILA 5EVBA 3IEKA 5AYAA 2P1EA 2FHXA 2BTNA 4LE6A 5LE1A 4XWTA 3F9OA 4TYFA 3X2ZA 5A23A 4FR7A 3RKJA 5K4NA 3S0ZA 4U4LA 3R2UA 3TP9A 4D1UA 1QH5A 4AXHA 5EWAA 5KIKA 4NQ2A 4EYBA 4O98A 4Z6XA 1YCFA 2Q0JA 1BMCA 4ZNBA 2BIBA 4RL2A 4D1WA 4AV7A 4RM5A 5AHOA 5FQAA 4EYLA 2YNUA 5HIPA 4GYQA 3AF5A 1VJNA 5K0WA 1M2XA 2CBNA 2I7TA 5ACUA 4KEQA 4TZEA 4PDXA 3SRXA 4TZBA 2FK6A 4Z7RA 2OHJA 3MD7A 2ZO4A 4UWSB 2AZ4A 1X8GA 4YSKA 5EVDA 1WRAA 2YNVA 2I7XA 4TYTA 5B1UA 4UAMA 5DPXA 1E5DA 1K07A 3T3NA 5ACPA 4UWOB 4C09A 4RBSA 3IEMA 3KNSA 4ZO3A 2BFZB 5ACXA 2OHHA 5A0TA 2AIOA 3ZNBA 4RAWA 1ZTCA 3WXCA 5LS3A 4AWZA 4EFZA 3ZQ4A 5FQCA 2HB9A 2BG7A 2YCBA 5EV6A 5AHRA 3ADRA 5FQBA 3SD9A 3IOFA 1BVTA 5ACTA 3KNRA 2QDSA 4C1CA 1KR3A 3X30A 4PVTA 4B87A 3LVZA 4HKYA 4NQ5A 3PY5A 4YSLA 4UWPB 2M5DA 3P2UA 5AJLA 3SBLA 3AF6A 5LMCA 2BG8B 2GCUA 1JJEA 3RKKA 4AX1B 2BGAA 5LSCA 4PVOA 4D1VA 4XUKA 3IELA 3JXPA 4XWWA 2FM6A 4BZ3A 1VGNA 5K4MA 1A8TA 1DD6A 1MQOA 2CFUA 3DHAA 3ZWFA 4KEPA 3BK1A 2FU9A 2QINA 5EH9A 3BK2A 5HH6A 2BFZA 3I14A 3A4YA 4AX0B 4FEKA 3I13A 1VMEA 2BC2A 3VPEA 2DKFA 3PG4A 5LCAA 2Q42A 1JJTA 2R2DA 1ZNBA 2NZFA 3FAIA 5HH5A 2A7MA 3DHCA 1JT1A 4C1FA 5LM6A 2BG6A 5AXOA 5B15A 2CG2A 1SMLA 1X8HA 2NYPA 4ZO2A 2P97A 5ACQA 4JO0A 4YSBA 5B3RA 5KILA 2BG8A 2Y8AA 5HIOA 4HL2A 5AXRA 2FU6A 3IOGA 2BMIA 3I11A 4P62A 2YNTB 5HISA 2BFLA 4NQ4A 3SFPA 2H6AA 1HLKA 4Z60A 1XTOA 3IE2A 1KO2A 5EHTA 4C1HA 5IQKA 2BFKA 2UYXA 1A7TA 3IE1A 1YCHA 1WUOA 4GYUA 4NQ6A 5LCHA 5ACSA 4J5FA 5A5ZA 4D02A 2NZEA 4RAMA 2WHGA 3G1PA 5EW0A 3Q6VA 5ACVA 1X8IA 5LCFA 4ZEJA 2QEDA 5A0VA 3IDZA 3QH8A 3T3OA 1BC2A 1DDKA 4Z5YA 2VW8A 3I0VA 2NXAA 4J5HA 3KL7A 2E7YA 4TZFA 3T9MA 4V0HA 4BP0A 4Z67A 4Z5ZA 1DXKA 2BR6A
chains in the Genus database with same CATH topology
2DOOA 3DH8A 3X2YA 3X2XA 1P9EA 1WUPA 4EY2A 5EVKA 2YNTA 4H0DA 1KO3A 3RPCA 4AD9A 4TZ9A 2YNWA 4F6ZA 3SW3A 2WRSA 4C1DA 5LLDA 1Y44A 4C1GA 1WW1A 3BV6A 4UWRB 2Y87A 1XM8A 2I7VA 2FHXB 4EYFA 2FU7A 2YZ3A 4EXSA 2GFJA 4GCWA 2QDTA 2XF4A 4RL0A 3VQZA 4UBQA 2ZWRA 5ACWA 2ZZIA 2BG2A 3SPUA 2GMNA 2WYMA 3DHBA 4F6HA 5A87A 3I15A 4D1TA 3FCZA 4C1EA 1QH3A 4CHLA 5K4KA 3IE0A 2P18A 4WD6A 4HL1A 5EV8A 1ZKPA 2ZNBA 2M5CA 4AWYB 4DIKA 2FU8A 3AJ3A 2P4ZA 3L6NA 3BC2A 2Q0IA 4UA4A 4EXYA 2QJSA 1L9YA 5AEBA 2WYMC 1YCGA 5HH4A 2OHIA 3ZR9A 2WYLA 5HIQA 5ACRA 3PY6A 3ESHA 2GKLA 2YNVB 2XR1A 4FSBA 2Y8BA 3H3EA 2GFKA 2Q9UA 4DILA 5EVBA 3IEKA 5AYAA 2P1EA 2FHXA 2BTNA 4LE6A 5LE1A 4XWTA 3F9OA 4TYFA 3X2ZA 4FR7A 3RKJA 5K4NA 3S0ZA 4U4LA 3R2UA 3TP9A 4D1UA 1QH5A 5EWAA 5KIKA 4NQ2A 4EYBA 4O98A 4Z6XA 1YCFA 2Q0JA 1BMCA 4ZNBA 2BIBA 4RL2A 4D1WA 4RM5A 5AHOA 5FQAA 4EYLA 2YNUA 5HIPA 4GYQA 3AF5A 1VJNA 5K0WA 1M2XA 2CBNA 2I7TA 5ACUA 4KEQA 4TZEA 3SRXA 4TZBA 2FK6A 4Z7RA 2OHJA 3MD7A 2ZO4A 4UWSB 2AZ4A 1X8GA 4YSKA 5EVDA 1WRAA 2YNVA 2I7XA 4TYTA 5B1UA 4UAMA 5DPXA 1E5DA 1K07A 3T3NA 5ACPA 4UWOB 4C09A 4RBSA 3IEMA 3KNSA 4ZO3A 2BFZB 5ACXA 2OHHA 5A0TA 2AIOA 3ZNBA 4RAWA 1ZTCA 3WXCA 5LS3A 4AWZA 4EFZA 3ZQ4A 5FQCA 2HB9A 2BG7A 2YCBA 5EV6A 5AHRA 3ADRA 5FQBA 3SD9A 3IOFA 1BVTA 5ACTA 3KNRA 2QDSA 4C1CA 1KR3A 3X30A 4PVTA 4B87A 3LVZA 4HKYA 4NQ5A 3PY5A 4YSLA 4UWPB 2M5DA 3P2UA 3SBLA 3AF6A 5LMCA 2BG8B 2GCUA 1JJEA 3RKKA 4AX1B 2BGAA 5LSCA 4PVOA 4D1VA 4XUKA 3IELA 3JXPA 4XWWA 2FM6A 4BZ3A 1VGNA 5K4MA 1A8TA 1DD6A 1MQOA 3DHAA 3ZWFA 4KEPA 3BK1A 2FU9A 2QINA 5EH9A 3BK2A 5HH6A 2BFZA 3I14A 3A4YA 4AX0B 4FEKA 3I13A 1VMEA 2BC2A 3VPEA 2DKFA 3PG4A 5LCAA 2Q42A 1JJTA 2R2DA 1ZNBA 2NZFA 3FAIA 5HH5A 2A7MA 3DHCA 1JT1A 4C1FA 5LM6A 2BG6A 5AXOA 5B15A 1SMLA 1X8HA 2NYPA 4ZO2A 2P97A 5ACQA 4JO0A 4YSBA 5B3RA 5KILA 2BG8A 2Y8AA 5HIOA 4HL2A 5AXRA 2FU6A 3IOGA 2BMIA 3I11A 4P62A 2YNTB 5HISA 2BFLA 4NQ4A 3SFPA 2H6AA 1HLKA 4Z60A 1XTOA 3IE2A 1KO2A 5EHTA 4C1HA 5IQKA 2BFKA 2UYXA 1A7TA 3IE1A 1YCHA 1WUOA 4GYUA 4NQ6A 5LCHA 5ACSA 4J5FA 5A5ZA 4D02A 2NZEA 4RAMA 2WHGA 3G1PA 5EW0A 3Q6VA 5ACVA 1X8IA 5LCFA 4ZEJA 2QEDA 5A0VA 3IDZA 3QH8A 3T3OA 1BC2A 1DDKA 4Z5YA 2VW8A 3I0VA 2NXAA 4J5HA 3KL7A 2E7YA 4TZFA 3T9MA 4V0HA 4BP0A 4Z67A 4Z5ZA 1DXKA 2BR6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DOO A;  3DH8 A;  3X2Y A;  3X2X A;  1P9E A;  1WUP A;  4EY2 A;  5EVK A;  2YNT A;  4H0D A;  1KO3 A;  3RPC A;  4AD9 A;  4TZ9 A;  2YNW A;  4F6Z A;  3SW3 A;  2WRS A;  4C1D A;  5LLD A;  1Y44 A;  4C1G A;  1WW1 A;  3BV6 A;  4UWR B;  2Y87 A;  1XM8 A;  2I7V A;  2FHX B;  4EYF A;  2FU7 A;  2YZ3 A;  4EXS A;  2GFJ A;  4GCW A;  2QDT A;  2XF4 A;  4RL0 A;  3VQZ A;  4UBQ A;  2ZWR A;  5ACW A;  2ZZI A;  2BG2 A;  3SPU A;  2GMN A;  2WYM A;  3DHB A;  4F6H A;  5A87 A;  3I15 A;  4D1T A;  3FCZ A;  4C1E A;  1QH3 A;  4CHL A;  5K4K A;  3IE0 A;  2P18 A;  4WD6 A;  4HL1 A;  5EV8 A;  1ZKP A;  2ZNB A;  2M5C A;  4AWY B;  4DIK A;  2FU8 A;  3AJ3 A;  2P4Z A;  3L6N A;  3BC2 A;  2Q0I A;  4UA4 A;  4EXY A;  2QJS A;  1L9Y A;  5AEB A;  2WYM C;  1YCG A;  5HH4 A;  2OHI A;  3ZR9 A;  2WYL A;  5HIQ A;  5ACR A;  3PY6 A;  3ESH A;  2GKL A;  2YNV B;  2XR1 A;  4FSB A;  2Y8B A;  3H3E A;  2GFK A;  2Q9U A;  4DIL A;  5EVB A;  3IEK A;  5AYA A;  2P1E A;  2FHX A;  2BTN A;  4LE6 A;  5LE1 A;  4XWT A;  3F9O A;  4TYF A;  3X2Z A;  4FR7 A;  3RKJ A;  5K4N A;  3S0Z A;  4U4L A;  3R2U A;  3TP9 A;  4D1U A;  1QH5 A;  5EWA A;  5KIK A;  4NQ2 A;  4EYB A;  4O98 A;  4Z6X A;  1YCF A;  2Q0J A;  1BMC A;  4ZNB A;  2BIB A;  4RL2 A;  4D1W A;  4RM5 A;  5AHO A;  5FQA A;  4EYL A;  2YNU A;  5HIP A;  4GYQ A;  3AF5 A;  1VJN A;  5K0W A;  1M2X A;  2CBN A;  2I7T A;  5ACU A;  4KEQ A;  4TZE A;  3SRX A;  4TZB A;  2FK6 A;  4Z7R A;  2OHJ A;  3MD7 A;  2ZO4 A;  4UWS B;  2AZ4 A;  1X8G A;  4YSK A;  5EVD A;  1WRA A;  2YNV A;  2I7X A;  4TYT A;  5B1U A;  4UAM A;  5DPX A;  1E5D A;  1K07 A;  3T3N A;  5ACP A;  4UWO B;  4C09 A;  4RBS A;  3IEM A;  3KNS A;  4ZO3 A;  2BFZ B;  5ACX A;  2OHH A;  5A0T A;  2AIO A;  3ZNB A;  4RAW A;  1ZTC A;  3WXC A;  5LS3 A;  4AWZ A;  4EFZ A;  3ZQ4 A;  5FQC A;  2HB9 A;  2BG7 A;  2YCB A;  5EV6 A;  5AHR A;  3ADR A;  5FQB A;  3SD9 A;  3IOF A;  1BVT A;  5ACT A;  3KNR A;  2QDS A;  4C1C A;  1KR3 A;  3X30 A;  4PVT A;  4B87 A;  3LVZ A;  4HKY A;  4NQ5 A;  3PY5 A;  4YSL A;  4UWP B;  2M5D A;  3P2U A;  3SBL A;  3AF6 A;  5LMC A;  2BG8 B;  2GCU A;  1JJE A;  3RKK A;  4AX1 B;  2BGA A;  5LSC A;  4PVO A;  4D1V A;  4XUK A;  3IEL A;  3JXP A;  4XWW A;  2FM6 A;  4BZ3 A;  1VGN A;  5K4M A;  1A8T A;  1DD6 A;  1MQO A;  3DHA A;  3ZWF A;  4KEP A;  3BK1 A;  2FU9 A;  2QIN A;  5EH9 A;  3BK2 A;  5HH6 A;  2BFZ A;  3I14 A;  3A4Y A;  4AX0 B;  4FEK A;  3I13 A;  1VME A;  2BC2 A;  3VPE A;  2DKF A;  3PG4 A;  5LCA A;  2Q42 A;  1JJT A;  2R2D A;  1ZNB A;  2NZF A;  3FAI A;  5HH5 A;  2A7M A;  3DHC A;  1JT1 A;  4C1F A;  5LM6 A;  2BG6 A;  5AXO A;  5B15 A;  1SML A;  1X8H A;  2NYP A;  4ZO2 A;  2P97 A;  5ACQ A;  4JO0 A;  4YSB A;  5B3R A;  5KIL A;  2BG8 A;  2Y8A A;  5HIO A;  4HL2 A;  5AXR A;  2FU6 A;  3IOG A;  2BMI A;  3I11 A;  4P62 A;  2YNT B;  5HIS A;  2BFL A;  4NQ4 A;  3SFP A;  2H6A A;  1HLK A;  4Z60 A;  1XTO A;  3IE2 A;  1KO2 A;  5EHT A;  4C1H A;  5IQK A;  2BFK A;  2UYX A;  1A7T A;  3IE1 A;  1YCH A;  1WUO A;  4GYU A;  4NQ6 A;  5LCH A;  5ACS A;  4J5F A;  5A5Z A;  4D02 A;  2NZE A;  4RAM A;  2WHG A;  3G1P A;  5EW0 A;  3Q6V A;  5ACV A;  1X8I A;  5LCF A;  4ZEJ A;  2QED A;  5A0V A;  3IDZ A;  3QH8 A;  3T3O A;  1BC2 A;  1DDK A;  4Z5Y A;  2VW8 A;  3I0V A;  2NXA A;  4J5H A;  3KL7 A;  2E7Y A;  4TZF A;  3T9M A;  4V0H A;  4BP0 A;  4Z67 A;  4Z5Z A;  1DXK A;  2BR6 A; 
#chains in the Genus database with same CATH topology
 2DOO A;  3DH8 A;  3X2Y A;  3X2X A;  1P9E A;  1WUP A;  4EY2 A;  5EVK A;  2YNT A;  4H0D A;  1KO3 A;  2CFZ A;  3RPC A;  4AD9 A;  4TZ9 A;  2YNW A;  4F6Z A;  3SW3 A;  2WRS A;  4C1D A;  5LLD A;  1Y44 A;  4C1G A;  1WW1 A;  3BV6 A;  5AIJ A;  4NUR A;  2Y87 A;  4UWR B;  1XM8 A;  2I7V A;  2FHX B;  4EYF A;  2FU7 A;  2YZ3 A;  4EXS A;  2GFJ A;  4GCW A;  2QDT A;  2CG3 A;  2XF4 A;  4RL0 A;  3VQZ A;  4UBQ A;  2ZWR A;  5ACW A;  2ZZI A;  2BG2 A;  3SPU A;  2GMN A;  2WYM A;  3DHB A;  4F6H A;  5A87 A;  3I15 A;  4D1T A;  3FCZ A;  4C1E A;  1QH3 A;  2YHE A;  4CHL A;  5K4K A;  3IE0 A;  2P18 A;  4WD6 A;  4HL1 A;  5EV8 A;  1ZKP A;  2ZNB A;  2M5C A;  4AWY B;  4DIK A;  2FU8 A;  3AJ3 A;  2P4Z A;  3L6N A;  3BC2 A;  2Q0I A;  4UA4 A;  4EXY A;  2QJS A;  1L9Y A;  5AEB A;  2WYM C;  1YCG A;  5HH4 A;  2OHI A;  3ZR9 A;  2WYL A;  5HIQ A;  5ACR A;  3PY6 A;  3ESH A;  2GKL A;  2YNV B;  2XR1 A;  4FSB A;  2Y8B A;  3H3E A;  2GFK A;  2Q9U A;  4DIL A;  5EVB A;  3IEK A;  5AYA A;  2P1E A;  2FHX A;  2BTN A;  4LE6 A;  5LE1 A;  4XWT A;  3F9O A;  4TYF A;  3X2Z A;  5A23 A;  4FR7 A;  3RKJ A;  5K4N A;  3S0Z A;  4U4L A;  3R2U A;  3TP9 A;  4D1U A;  1QH5 A;  4AXH A;  5EWA A;  5KIK A;  4NQ2 A;  4EYB A;  4O98 A;  4Z6X A;  1YCF A;  2Q0J A;  1BMC A;  4ZNB A;  2BIB A;  4RL2 A;  4D1W A;  4AV7 A;  4RM5 A;  5AHO A;  5FQA A;  4EYL A;  2YNU A;  5HIP A;  4GYQ A;  3AF5 A;  1VJN A;  5K0W A;  1M2X A;  2CBN A;  2I7T A;  5ACU A;  4KEQ A;  4TZE A;  4PDX A;  3SRX A;  4TZB A;  2FK6 A;  4Z7R A;  2OHJ A;  3MD7 A;  2ZO4 A;  4UWS B;  2AZ4 A;  1X8G A;  4YSK A;  5EVD A;  1WRA A;  2YNV A;  2I7X A;  4TYT A;  5B1U A;  4UAM A;  5DPX A;  1E5D A;  1K07 A;  3T3N A;  5ACP A;  4UWO B;  4C09 A;  4RBS A;  3IEM A;  3KNS A;  4ZO3 A;  2BFZ B;  5ACX A;  2OHH A;  5A0T A;  2AIO A;  3ZNB A;  4RAW A;  1ZTC A;  3WXC A;  5LS3 A;  4AWZ A;  4EFZ A;  3ZQ4 A;  5FQC A;  2HB9 A;  2BG7 A;  2YCB A;  5EV6 A;  5AHR A;  3ADR A;  5FQB A;  3SD9 A;  3IOF A;  1BVT A;  5ACT A;  3KNR A;  2QDS A;  4C1C A;  1KR3 A;  3X30 A;  4PVT A;  4B87 A;  3LVZ A;  4HKY A;  4NQ5 A;  3PY5 A;  4YSL A;  4UWP B;  2M5D A;  3P2U A;  5AJL A;  3SBL A;  3AF6 A;  5LMC A;  2BG8 B;  2GCU A;  1JJE A;  3RKK A;  4AX1 B;  2BGA A;  5LSC A;  4PVO A;  4D1V A;  4XUK A;  3IEL A;  3JXP A;  4XWW A;  2FM6 A;  4BZ3 A;  1VGN A;  5K4M A;  1A8T A;  1DD6 A;  1MQO A;  2CFU A;  3DHA A;  3ZWF A;  4KEP A;  3BK1 A;  2FU9 A;  2QIN A;  5EH9 A;  3BK2 A;  5HH6 A;  2BFZ A;  3I14 A;  3A4Y A;  4AX0 B;  4FEK A;  3I13 A;  1VME A;  2BC2 A;  3VPE A;  2DKF A;  3PG4 A;  5LCA A;  2Q42 A;  1JJT A;  2R2D A;  1ZNB A;  2NZF A;  3FAI A;  5HH5 A;  2A7M A;  3DHC A;  1JT1 A;  4C1F A;  5LM6 A;  2BG6 A;  5AXO A;  5B15 A;  2CG2 A;  1SML A;  1X8H A;  2NYP A;  4ZO2 A;  2P97 A;  5ACQ A;  4JO0 A;  4YSB A;  5B3R A;  5KIL A;  2BG8 A;  2Y8A A;  5HIO A;  4HL2 A;  5AXR A;  2FU6 A;  3IOG A;  2BMI A;  3I11 A;  4P62 A;  2YNT B;  5HIS A;  2BFL A;  4NQ4 A;  3SFP A;  2H6A A;  1HLK A;  4Z60 A;  1XTO A;  3IE2 A;  1KO2 A;  5EHT A;  4C1H A;  5IQK A;  2BFK A;  2UYX A;  1A7T A;  3IE1 A;  1YCH A;  1WUO A;  4GYU A;  4NQ6 A;  5LCH A;  5ACS A;  4J5F A;  5A5Z A;  4D02 A;  2NZE A;  4RAM A;  2WHG A;  3G1P A;  5EW0 A;  3Q6V A;  5ACV A;  1X8I A;  5LCF A;  4ZEJ A;  2QED A;  5A0V A;  3IDZ A;  3QH8 A;  3T3O A;  1BC2 A;  1DDK A;  4Z5Y A;  2VW8 A;  3I0V A;  2NXA A;  4J5H A;  3KL7 A;  2E7Y A;  4TZF A;  3T9M A;  4V0H A;  4BP0 A;  4Z67 A;  4Z5Z A;  1DXK A;  2BR6 A; 
#chains in the Genus database with same CATH homology
 2DOO A;  3DH8 A;  3X2Y A;  3X2X A;  1P9E A;  1WUP A;  4EY2 A;  5EVK A;  2YNT A;  4H0D A;  1KO3 A;  3RPC A;  4AD9 A;  4TZ9 A;  2YNW A;  4F6Z A;  3SW3 A;  2WRS A;  4C1D A;  5LLD A;  1Y44 A;  4C1G A;  1WW1 A;  3BV6 A;  4UWR B;  2Y87 A;  1XM8 A;  2I7V A;  2FHX B;  4EYF A;  2FU7 A;  2YZ3 A;  4EXS A;  2GFJ A;  4GCW A;  2QDT A;  2XF4 A;  4RL0 A;  3VQZ A;  4UBQ A;  2ZWR A;  5ACW A;  2ZZI A;  2BG2 A;  3SPU A;  2GMN A;  2WYM A;  3DHB A;  4F6H A;  5A87 A;  3I15 A;  4D1T A;  3FCZ A;  4C1E A;  1QH3 A;  4CHL A;  5K4K A;  3IE0 A;  2P18 A;  4WD6 A;  4HL1 A;  5EV8 A;  1ZKP A;  2ZNB A;  2M5C A;  4AWY B;  4DIK A;  2FU8 A;  3AJ3 A;  2P4Z A;  3L6N A;  3BC2 A;  2Q0I A;  4UA4 A;  4EXY A;  2QJS A;  1L9Y A;  5AEB A;  2WYM C;  1YCG A;  5HH4 A;  2OHI A;  3ZR9 A;  2WYL A;  5HIQ A;  5ACR A;  3PY6 A;  3ESH A;  2GKL A;  2YNV B;  2XR1 A;  4FSB A;  2Y8B A;  3H3E A;  2GFK A;  2Q9U A;  4DIL A;  5EVB A;  3IEK A;  5AYA A;  2P1E A;  2FHX A;  2BTN A;  4LE6 A;  5LE1 A;  4XWT A;  3F9O A;  4TYF A;  3X2Z A;  4FR7 A;  3RKJ A;  5K4N A;  3S0Z A;  4U4L A;  3R2U A;  3TP9 A;  4D1U A;  1QH5 A;  5EWA A;  5KIK A;  4NQ2 A;  4EYB A;  4O98 A;  4Z6X A;  1YCF A;  2Q0J A;  1BMC A;  4ZNB A;  2BIB A;  4RL2 A;  4D1W A;  4RM5 A;  5AHO A;  5FQA A;  4EYL A;  2YNU A;  5HIP A;  4GYQ A;  3AF5 A;  1VJN A;  5K0W A;  1M2X A;  2CBN A;  2I7T A;  5ACU A;  4KEQ A;  4TZE A;  3SRX A;  4TZB A;  2FK6 A;  4Z7R A;  2OHJ A;  3MD7 A;  2ZO4 A;  4UWS B;  2AZ4 A;  1X8G A;  4YSK A;  5EVD A;  1WRA A;  2YNV A;  2I7X A;  4TYT A;  5B1U A;  4UAM A;  5DPX A;  1E5D A;  1K07 A;  3T3N A;  5ACP A;  4UWO B;  4C09 A;  4RBS A;  3IEM A;  3KNS A;  4ZO3 A;  2BFZ B;  5ACX A;  2OHH A;  5A0T A;  2AIO A;  3ZNB A;  4RAW A;  1ZTC A;  3WXC A;  5LS3 A;  4AWZ A;  4EFZ A;  3ZQ4 A;  5FQC A;  2HB9 A;  2BG7 A;  2YCB A;  5EV6 A;  5AHR A;  3ADR A;  5FQB A;  3SD9 A;  3IOF A;  1BVT A;  5ACT A;  3KNR A;  2QDS A;  4C1C A;  1KR3 A;  3X30 A;  4PVT A;  4B87 A;  3LVZ A;  4HKY A;  4NQ5 A;  3PY5 A;  4YSL A;  4UWP B;  2M5D A;  3P2U A;  3SBL A;  3AF6 A;  5LMC A;  2BG8 B;  2GCU A;  1JJE A;  3RKK A;  4AX1 B;  2BGA A;  5LSC A;  4PVO A;  4D1V A;  4XUK A;  3IEL A;  3JXP A;  4XWW A;  2FM6 A;  4BZ3 A;  1VGN A;  5K4M A;  1A8T A;  1DD6 A;  1MQO A;  3DHA A;  3ZWF A;  4KEP A;  3BK1 A;  2FU9 A;  2QIN A;  5EH9 A;  3BK2 A;  5HH6 A;  2BFZ A;  3I14 A;  3A4Y A;  4AX0 B;  4FEK A;  3I13 A;  1VME A;  2BC2 A;  3VPE A;  2DKF A;  3PG4 A;  5LCA A;  2Q42 A;  1JJT A;  2R2D A;  1ZNB A;  2NZF A;  3FAI A;  5HH5 A;  2A7M A;  3DHC A;  1JT1 A;  4C1F A;  5LM6 A;  2BG6 A;  5AXO A;  5B15 A;  1SML A;  1X8H A;  2NYP A;  4ZO2 A;  2P97 A;  5ACQ A;  4JO0 A;  4YSB A;  5B3R A;  5KIL A;  2BG8 A;  2Y8A A;  5HIO A;  4HL2 A;  5AXR A;  2FU6 A;  3IOG A;  2BMI A;  3I11 A;  4P62 A;  2YNT B;  5HIS A;  2BFL A;  4NQ4 A;  3SFP A;  2H6A A;  1HLK A;  4Z60 A;  1XTO A;  3IE2 A;  1KO2 A;  5EHT A;  4C1H A;  5IQK A;  2BFK A;  2UYX A;  1A7T A;  3IE1 A;  1YCH A;  1WUO A;  4GYU A;  4NQ6 A;  5LCH A;  5ACS A;  4J5F A;  5A5Z A;  4D02 A;  2NZE A;  4RAM A;  2WHG A;  3G1P A;  5EW0 A;  3Q6V A;  5ACV A;  1X8I A;  5LCF A;  4ZEJ A;  2QED A;  5A0V A;  3IDZ A;  3QH8 A;  3T3O A;  1BC2 A;  1DDK A;  4Z5Y A;  2VW8 A;  3I0V A;  2NXA A;  4J5H A;  3KL7 A;  2E7Y A;  4TZF A;  3T9M A;  4V0H A;  4BP0 A;  4Z67 A;  4Z5Z A;  1DXK A;  2BR6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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