The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
177
|
sequence length |
913
|
structure length |
871
|
Chain Sequence |
CFCDHYAWTQWTSCSKTCNSGTQSRHRQIVVDKYYQENFCEQICSKQETRECNWQRCPINCLLGDFGPWSDCDPCIEKQSKVRSVLRPSQFGGQPCTAPLVAFQPCIPSKLCKIEEADCKNKFRCDSGRCIARKLECNGENDCGDNSDERDCGRTKAVCTRKYNPIPSVQLMGNGFHFLAGEPRGEVLDNSFTGGICKTVKSSRTSNPYRVPANLENVGFEVQTAEDDLKTDFYKDLTSLGHVPIFYSSKRSENINHNSAFKQAIQASHKKDSSFIRIHKVMKVLNFTTKAKDLHLSDVFLKALNHLPLEYNSALYSRIFDDFGTHYFTSGSLGGVYDLLYQFSSEELKNSGLTEEEAKHCVRIETKKRVLFAKKTKVEHRCTTNKLSEKHEGSFIQGAEKSISLIRGGRSEYGAALAWEKGSSGLEEKTFSEWLESVKENPAVIDFELAPIVDLVRNIPCAVTKRNNLRKALQEYAAKFDPCQCAPCPNNGRPTLSGTECLCVCQSGTYGENCEKQSPDYKSNAVDGQWGCWSSWSTCDATYKRSRTRECNNPAPQRGGKRCEGEKRQEEDCTPCINDDEEDSGCPQPVPPENGFIRNEKQLYLVGEDVEISCLTGFETVGYQYFRCLPDGTWRQGDVECQRTECIKPVVQEVLTITPFQRLYRIGESIELTCPKGFVVAGPSRYTCQGNSWTPPISNSLTCEKDTGHCQLGQKQSGSECICMSPEEDCSHHSEDLCVFDTDSNDYFTSPACKFLAEKCLNNQQLHFLHIGSCQDGRQLEWGLERTRLSSNSTKKESCGYDTCYDWEKCSASTSKCVCLLPPQCFKGGNQLYCVKMGSSTSEKTLNICEVGTIRCANRKMEILHPGKCLA
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structure of Complement C6 Suggests a Mechanism for Initiation and Unidirectional, Sequential Assembly of Membrane Attack Complex (MAC).
pubmed doi rcsb |
| molecule tags |
Immune system
|
| molecule keywords |
Complement component C6
|
| total genus |
177
|
| structure length |
871
|
| sequence length |
913
|
| ec nomenclature | |
| pdb deposition date | 2011-07-27 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00057 | Ldl_recept_a | Low-density lipoprotein receptor domain class A |
| A | PF00084 | Sushi | Sushi repeat (SCR repeat) |
| A | PF00090 | TSP_1 | Thrombospondin type 1 domain |
| A | PF01823 | MACPF | MAC/Perforin domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Beta | Ribbon | Complement Module; domain 1 | Complement Module, domain 1 | ||
| Mainly Beta | Ribbon | Complement Module; domain 1 | Complement Module, domain 1 | ||
| Mainly Beta | Single Sheet | TSP-1 type 1 repeat | Thrombospondin type-1 (TSP1) repeat |
#chains in the Genus database with same CATH superfamily 1E88 A; 2EC3 A; 5FO8 C; 4AYE A; 3GXE A; 4C16 A; 1C1Z A; 1ELV A; 2YBY A; 3VDK A; 1H04 P; 5HYT B; 4IGD A; 4AYM A; 3R6B A; 4LOT A; 2XWB F; 3L89 M; 3RJ3 D; 2JGW A; 2QY0 A; 2EHF A; 1FBR A; 2B5I D; 3KXV A; 2A55 A; 2CG7 A; 4HQO A; 2BZM A; 4ZH1 D; 2RL0 A; 1OK9 A; 3INB C; 4B2S A; 1MD8 A; 2RLP A; 2MCZ A; 2KMS A; 5HZP B; 1QO6 A; 2XQW C; 4CSY A; 1G4F A; 4A5W B; 1TPG A; 2G7I A; 2V8E A; 2RLQ A; 1H03 P; 1LSL A; 3OP8 A; 1GPZ A; 1Q3X A; 2JGX A; 2IZ3 A; 5JPM G; 1MD7 A; 3R62 A; 2RKY A; 3ZD1 A; 4K12 A; 1TPM A; 3ZD2 A; 4AYD A; 4F4O C; 1UOT P; 1SZL A; 4DJZ A; 1GKN A; 1H2P P; 1Z92 B; 1HFI A; 2ERJ A; 1QUB A; 1TPN A; 4HQL A; 2KRI A; 3GOV A; 1O9A A; 1OJV A; 3TVJ A; 4JHS A; 1GHQ B; 2WII C; 1SS2 A; 3OED C; 1VVC A; 3SW0 X; 3ZRZ A; 2W81 A; 1G4G A; 1GKG A; 2CKU A; 4KKD A; 4YNX A; 3O8E B; 3CAL A; 2XWJ I; 1OK1 A; 1NWV A; 4FXG G; 1PPQ A; 2YRA A; 3VDJ A; 1QGB A; 3VDL A; 2MCY A; 1HCC A; 2O39 C; 5HYP A; 1CKL A; 5I0Q B; 4PZ5 A; 1HFH A; 1OK3 A; 3M7P A; 3NFP I; 4HQN A; 1ZJK A; 3ERB A; 2XRD A; 2RKZ A; 3EJH A; 4ONT D; 2W80 A; 4MUC A; 3IX0 A; 4AYI A; 3T5O A; 1LY2 A; 1E5G A; 2IZ4 A; 1OJY A; 3MQL A; 2LOJ A; 1U5M A; 2XRB A; 2CG6 A; 1OJW A; 1SRZ A; 5HYU B; 1VEX A; 3OXU D; 3IU3 I; 4WJG 2; 1H2Q P; 4B2R A; 2JRA A; 4J38 B; 1OK2 A; 1VVD A; 2UWN A; 3KZJ A; 1E8B A; 4LOS A; #chains in the Genus database with same CATH topology 1E88 A; 2EC3 A; 5FO8 C; 4AYE A; 3GXE A; 4C16 A; 1C1Z A; 1ELV A; 2YBY A; 3VDK A; 1H04 P; 5HYT B; 4IGD A; 4AYM A; 3R6B A; 4LOT A; 2XWB F; 3L89 M; 3RJ3 D; 4BWC A; 2JGW A; 2QY0 A; 2EHF A; 1FBR A; 2B5I D; 2Y8T A; 2A55 A; 3KXV A; 2CG7 A; 2I2L A; 4HQO A; 2BZM A; 3K3T A; 4YIZ A; 4ZH1 D; 2RL0 A; 3FGT A; 1OK9 A; 3INB C; 4B2S A; 4MSL A; 1MD8 A; 2RLP A; 2MCZ A; 2KMS A; 5HZP B; 1QO6 A; 4APL A; 2XQW C; 4CSY A; 1G4F A; 4A5W B; 1TPG A; 3CI0 J; 2G7I A; 2V8E A; 3ZLD A; 2RLQ A; 4N7E A; 3ZLE A; 1H03 P; 1LSL A; 3OP8 A; 1GPZ A; 1Q3X A; 3FGR A; 2JGX A; 2IZ3 A; 5JPM G; 1MD7 A; 3R62 A; 2RKY A; 3ZD1 A; 4K12 A; 1TPM A; 3ZD2 A; 4AYD A; 4F4O C; 1UOT P; 1SZL A; 4DJZ A; 1GKN A; 1H2P P; 1Z92 B; 1HFI A; 2ERJ A; 1QUB A; 2ZYC A; 3VWO A; 1TPN A; 4HQL A; 2KRI A; 3GOV A; 1O9A A; 1OJV A; 3TVJ A; 4JHS A; 1GHQ B; 2WII C; 1SS2 A; 3OED C; 1VVC A; 3SW0 X; 3ZRZ A; 2W81 A; 1G4G A; 2Y8S A; 1GKG A; 2CKU A; 4KKD A; 4YNX A; 3O8E B; 3CAL A; 2XWJ I; 1OK1 A; 1NWV A; 4FXG G; 1PPQ A; 2YRA A; 3VDJ A; 1QGB A; 5DN4 A; 3VDL A; 2MCY A; 1HCC A; 2O39 C; 5HYP A; 1CKL A; 5I0Q B; 4PZ5 A; 1HFH A; 1OK3 A; 4PO7 A; 1RLH A; 3M7P A; 3NFP I; 4HQN A; 1ZJK A; 3ERB A; 2XRD A; 2RKZ A; 3EJH A; 4ONT D; 2W80 A; 4MUC A; 3WSX A; 3IX0 A; 5DN5 A; 4AYI A; 3T5O A; 1LY2 A; 1E5G A; 2Y8R A; 2IZ4 A; 1OJY A; 3MQL A; 2LOJ A; 1U5M A; 2XRB A; 2CG6 A; 2X2Z A; 1OJW A; 3F6K A; 1SRZ A; 5HYU B; 1VEX A; 3OXU D; 3IU3 I; 4WJG 2; 3NJA A; 1H2Q P; 4B2R A; 2JRA A; 4J38 B; 1OK2 A; 1VVD A; 2UWN A; 3KZJ A; 1E8B A; 3WSY A; 4LOS A; #chains in the Genus database with same CATH homology 1E88 A; 2EC3 A; 5FO8 C; 4AYE A; 3GXE A; 4C16 A; 1C1Z A; 1ELV A; 2YBY A; 3VDK A; 1H04 P; 5HYT B; 4IGD A; 4AYM A; 3R6B A; 4LOT A; 2XWB F; 3L89 M; 3RJ3 D; 2JGW A; 2QY0 A; 2EHF A; 1FBR A; 2B5I D; 3KXV A; 2A55 A; 2CG7 A; 4HQO A; 2BZM A; 4ZH1 D; 2RL0 A; 1OK9 A; 3INB C; 4B2S A; 1MD8 A; 2RLP A; 2MCZ A; 2KMS A; 5HZP B; 1QO6 A; 2XQW C; 4CSY A; 1G4F A; 4A5W B; 1TPG A; 2G7I A; 2V8E A; 2RLQ A; 1H03 P; 1LSL A; 3OP8 A; 1GPZ A; 1Q3X A; 2JGX A; 2IZ3 A; 5JPM G; 1MD7 A; 3R62 A; 2RKY A; 3ZD1 A; 4K12 A; 1TPM A; 3ZD2 A; 4AYD A; 4F4O C; 1UOT P; 1SZL A; 4DJZ A; 1GKN A; 1H2P P; 1Z92 B; 1HFI A; 2ERJ A; 1QUB A; 1TPN A; 4HQL A; 2KRI A; 3GOV A; 1O9A A; 1OJV A; 3TVJ A; 4JHS A; 1GHQ B; 2WII C; 1SS2 A; 3OED C; 1VVC A; 3SW0 X; 3ZRZ A; 2W81 A; 1G4G A; 1GKG A; 2CKU A; 4KKD A; 4YNX A; 3O8E B; 3CAL A; 2XWJ I; 1OK1 A; 1NWV A; 4FXG G; 1PPQ A; 2YRA A; 3VDJ A; 1QGB A; 3VDL A; 2MCY A; 1HCC A; 2O39 C; 5HYP A; 1CKL A; 5I0Q B; 4PZ5 A; 1HFH A; 1OK3 A; 3M7P A; 3NFP I; 4HQN A; 1ZJK A; 3ERB A; 2XRD A; 2RKZ A; 3EJH A; 4ONT D; 2W80 A; 4MUC A; 3IX0 A; 4AYI A; 3T5O A; 1LY2 A; 1E5G A; 2IZ4 A; 1OJY A; 3MQL A; 2LOJ A; 1U5M A; 2XRB A; 2CG6 A; 1OJW A; 1SRZ A; 5HYU B; 1VEX A; 3OXU D; 3IU3 I; 4WJG 2; 1H2Q P; 4B2R A; 2JRA A; 4J38 B; 1OK2 A; 1VVD A; 2UWN A; 3KZJ A; 1E8B A; 4LOS A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
