1K90 | Genus

Total Genus 135

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	135
sequence length	507
structure length	485
Chain Sequence	RIDVLKGEKALKASGLVPEHADAFKKIARELNTYILFRPVNKLATNLIKSGVATKGLNVHGKSSDWGPVAGYIPFDQDLSKKHGQQLAVEKGNLENKKSITEHEGEIGKIPLKLDHLRIEELKENGIILKGKKEIDNGKKYYLLESNNQVYEFRISDENNEVQYKTKEGKITVLGEKFNWRNIEVMAKNVEGVLKPLTADYDLFALAPSLTEIKKQIPQKEWDKVVNTPNSLEKQKGVTNLLIKYGIERKPDSTKGTLSNWQKQMLDRLNEAVKYTGYTGGDVVNHGTEQDNEEFPEKDNEIFIINPEGEFILTKNWEMTGRFIEKNITGKDYLYYFNRSYNKIAPGNKAYIEWTDPITKAKINTIPTSAEFIKNLSSIRRSSSVKKIAGYLSDYYNSANHIFSQEKKRKISIFRGIQAYNEIENVLKSKQIAPEYKNYFQYLKERITNQVQLLLTHQKFKLLYKQLNFTENETDNFEVFQKIID

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 485 atoms

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485 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Toxin,lyase/metal binding protein
source organism	Bacillus anthracis
publication title	Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin. pubmed doi rcsb
molecule keywords	CALMODULIN-SENSITIVE ADENYLATE CYCLASE
total genus	135
structure length	485
sequence length	507
chains with identical sequence	B, C
ec nomenclature	ec 4.6.1.1: Adenylate cyclase.
pdb deposition date	2001-10-26

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF03497	Anthrax_toxA	Anthrax toxin LF subunit

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.140.60	Mainly Alpha	Up-down Bundle	Butyryl-CoA Dehydrogenase, subunit A; domain 3	Butyryl-CoA Dehydrogenase, subunit A; domain 3	1k90A03
3.90.1760.10	Alpha Beta	Alpha-Beta Complex	Adenylylcyclase toxin fold	Anthrax toxin, edema factor, central domain	1k90A02

1PK0A 1YRTA 1K93A 2COLA 1XFVA 1K90A 1S26A 1XFWA 1YRUA 1SK6A 1XFUA 1ZOTA 1K8TA 1Y0VA 1XFYA 1LVCA 1XFZA 1XFXA
chains in the Genus database with same CATH superfamily

4RM7A 2BU2A 3MDEA 3D9DA 1EGEA 4Q17A 4X28C 2JBRA 2AZEA 2DVLA 1RP3A 2REHA 2YYMA 3OWAA 4OO2A 4W9UA 3S7WA 3Q24A 2R0MA 3FO3A 1OAHA 4KTOA 5J6AA 1SIQA 2RDZA 3TZ4A 1X8ZA 1PK0A 1Y8PA 3KMLA 4WJYA 4JIOA 2CJ6A 2Q8IA 3TORA 1GKXA 2R05A 4KS9A 2QR4A 2R0NA 1R2JA 1LVCA 1QDBA 1X90A 3AFEA 4FF2A 4L3ZA 5GJWE 3B96A 3TZ2A 1RJ1A 3VKHA 4JEKA 4M9AA 3VKGA 1PI1A 1EGDA 4IRNA 1Y0VA 3F29A 2CX9A 3II9A 2Z1QA 2Q8HA 2F6LA 4G97A 2EBFX 4E02A 4L38A 1Y8OA 4NXLA 3SXQA 2VR0A 4L3XA 1XFUA 2CJ4A 2ZDYA 5B5WA 4P13A 3R7KA 2JBTA 3MPIA 4L1FA 1IVHA 3RKHA 5K3GA 1K93A 4MPCA 3PFDA 2OJQA 2ZAFA 2PG0A 2E0AA 3NF4A 2CJ7A 4HKSA 4LQQB 4MPNA 4F0XA 4ZYJA 4G5EA 2IX5A 2OR0A 2J7AA 2AO2A 2BTZA 2D29A 3MDDA 4FF4A 1GJVA 2FP2A 2RF7A 3GM6A 2JIFA 5K3IA 2FP1A 2R02A 3D1IA 3L1TA 2YYLA 2BU6A 3CRKA 3P4TA 1XFZA 3VADA 1JM6A 1BUCA 4Q4UA 2CJ5A 3BNFA 2Q8FA 1RJ4A 3EOMA 1K90A 3D9GA 2YYJA 3D9EA 1EGCA 2YYGA 3MPJA 5M4KA 3Q23A 4JIZA 1WS9A 3TZ0A 5K3HA 2EBAA 5B5VA 4AKIA 4IV6A 1XFVA 2ZKJA 2OEVA 4MP7A 3CE2A 1GU6A 4LQSB 4Q1OA 5K3JA 4H81A 2LFWA 3C46A 2IX6A 2XQRB 3MKHA 4AKGA 5BRKA 1YRUA 3UBRA 2WBIA 1SIRA 2HJNA 3BNHA 3D6BA 1R3BA 2PNRA 2Q8GA 1XFWA 1GKZA 1U8VA 5M4NA 1K8TA 2EBHX 3HWCA 1XG2B 3LG1A 4U83A 4Q5BA 3AFFA 4HKRA 2DDHA 5GJVE 2E80A 4DZYA 4HR3A 2OEXA 3MXLA 2RFQA 5J71A 4KCFA 3LGQA 4V25A 4V26A 1T9GA 2COLA 2ZO5A 3X29A 2JBSA 4Q0TA 4H7QA 5M4PA 2YYKA 1FS7A 3X0XA 3EONA 1FS8A 2PO4A 3TTBA 1SK6A 4FZ4A 4MP2A 4E01A 1ZOTA 2BU8A 3BNJA 3BNGA 3M9VA 2OT4A 3SF6A 4Q5CA 3D9FA 3CRLA 3FCJA 3GNCA 1UKWA 1W07A 2C0UA 4AI6A 2R03A 2XS8A 3SWOA 4J1VA 4H85A 2CJ8A 4DOYA 4KSAA 3SCEA 4KSFA 4L3YA 4XVXA 1X91A 1FS9A 1JQIA 1S26A 2A1TA 3X0YA 5B6BA 5BRMA 3GQTA 3C3LA 2VIGA 3MMOA 1XFYA 4ZXVA 3C2PA 3Q22A 2GBBA 2XS1A 2YGWA 2FONA 2YYIA 4X28A 3OIBA 4MPEA 4FF1A 4FF3A 4O5MA 4P79A 3Q0AA 2E81A 2UXWA 1IS2A 3UU9A 1Y8NA 1XFXA 3OWMA 2C12A 4AKHA 4N5FA 1YRTA 1RX0A 4QICA 3D2RA 2EC5A 2ZDXA 4E00A 1UDYA 5M4MA 2VF1A 3TZ5A 1SC5A 2BU7A 2BU5A 3N0RA
chains in the Genus database with same CATH topology

1K93A 4AKIA 1XFVA 4AI6A 2AZEA 1RP3A 4HKSA 3CE2A 4F0XA 3Q24A 2LFWA 3C46A 1YRUA 4AKGA 1PK0A 4KSAA 3KMLA 4KSFA 1S26A 1XFWA 2AO2A 4KS9A 4FF4A 2QR4A 1K8TA 2EBHX 2FP2A 3C3LA 1XFYA 1LVCA 3C2PA 4HKRA 5GJVE 3Q22A 2GBBA 2YGWA 4FF2A 5GJWE 1YRTA 2FP1A 2COLA 4FF3A 3VKHA 4P79A 3X29A 3Q0AA 3VKGA 1Y0VA 1XFZA 1XFXA 2F6LA 2PO4A 4G97A 4AKHA 2EBFX 4QICA 2EC5A 1K90A 1SK6A 1XFUA 2VF1A 4FZ4A 1ZOTA 3Q23A 1SC5A 4FF1A 3N0RA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 1PK0 A;  1YRT A;  1K93 A;  2COL A;  1XFV A;  1K90 A;  1S26 A;  1XFW A;  1YRU A;  1SK6 A;  1XFU A;  1ZOT A;  1K8T A;  1Y0V A;  1XFY A;  1LVC A;  1XFZ A;  1XFX A; 
#chains in the Genus database with same CATH topology
 4RM7 A;  2BU2 A;  3MDE A;  3D9D A;  1EGE A;  4Q17 A;  4X28 C;  2JBR A;  2AZE A;  2DVL A;  1RP3 A;  2REH A;  2YYM A;  3OWA A;  4OO2 A;  4W9U A;  3S7W A;  3Q24 A;  2R0M A;  3FO3 A;  1OAH A;  4KTO A;  5J6A A;  1SIQ A;  2RDZ A;  3TZ4 A;  1X8Z A;  1PK0 A;  1Y8P A;  3KML A;  4WJY A;  4JIO A;  2CJ6 A;  2Q8I A;  3TOR A;  1GKX A;  2R05 A;  4KS9 A;  2QR4 A;  2R0N A;  1R2J A;  1LVC A;  1QDB A;  1X90 A;  3AFE A;  4FF2 A;  4L3Z A;  5GJW E;  3B96 A;  3TZ2 A;  1RJ1 A;  3VKH A;  4JEK A;  4M9A A;  3VKG A;  1PI1 A;  1EGD A;  4IRN A;  1Y0V A;  3F29 A;  2CX9 A;  3II9 A;  2Z1Q A;  2Q8H A;  2F6L A;  4G97 A;  2EBF X;  4E02 A;  4L38 A;  1Y8O A;  4NXL A;  3SXQ A;  2VR0 A;  4L3X A;  1XFU A;  2CJ4 A;  2ZDY A;  5B5W A;  4P13 A;  3R7K A;  2JBT A;  3MPI A;  4L1F A;  1IVH A;  3RKH A;  5K3G A;  1K93 A;  4MPC A;  3PFD A;  2OJQ A;  2ZAF A;  2PG0 A;  2E0A A;  3NF4 A;  2CJ7 A;  4HKS A;  4LQQ B;  4MPN A;  4F0X A;  4ZYJ A;  4G5E A;  2IX5 A;  2OR0 A;  2J7A A;  2AO2 A;  2BTZ A;  2D29 A;  3MDD A;  4FF4 A;  1GJV A;  2FP2 A;  2RF7 A;  3GM6 A;  2JIF A;  5K3I A;  2FP1 A;  2R02 A;  3D1I A;  3L1T A;  2YYL A;  2BU6 A;  3CRK A;  3P4T A;  1XFZ A;  3VAD A;  1JM6 A;  1BUC A;  4Q4U A;  2CJ5 A;  3BNF A;  2Q8F A;  1RJ4 A;  3EOM A;  1K90 A;  3D9G A;  2YYJ A;  3D9E A;  1EGC A;  2YYG A;  3MPJ A;  5M4K A;  3Q23 A;  4JIZ A;  1WS9 A;  3TZ0 A;  5K3H A;  2EBA A;  5B5V A;  4AKI A;  4IV6 A;  1XFV A;  2ZKJ A;  2OEV A;  4MP7 A;  3CE2 A;  1GU6 A;  4LQS B;  4Q1O A;  5K3J A;  4H81 A;  2LFW A;  3C46 A;  2IX6 A;  2XQR B;  3MKH A;  4AKG A;  5BRK A;  1YRU A;  3UBR A;  2WBI A;  1SIR A;  2HJN A;  3BNH A;  3D6B A;  1R3B A;  2PNR A;  2Q8G A;  1XFW A;  1GKZ A;  1U8V A;  5M4N A;  1K8T A;  2EBH X;  3HWC A;  1XG2 B;  3LG1 A;  4U83 A;  4Q5B A;  3AFF A;  4HKR A;  2DDH A;  5GJV E;  2E80 A;  4DZY A;  4HR3 A;  2OEX A;  3MXL A;  2RFQ A;  5J71 A;  4KCF A;  3LGQ A;  4V25 A;  4V26 A;  1T9G A;  2COL A;  2ZO5 A;  3X29 A;  2JBS A;  4Q0T A;  4H7Q A;  5M4P A;  2YYK A;  1FS7 A;  3X0X A;  3EON A;  1FS8 A;  2PO4 A;  3TTB A;  1SK6 A;  4FZ4 A;  4MP2 A;  4E01 A;  1ZOT A;  2BU8 A;  3BNJ A;  3BNG A;  3M9V A;  2OT4 A;  3SF6 A;  4Q5C A;  3D9F A;  3CRL A;  3FCJ A;  3GNC A;  1UKW A;  1W07 A;  2C0U A;  4AI6 A;  2R03 A;  2XS8 A;  3SWO A;  4J1V A;  4H85 A;  2CJ8 A;  4DOY A;  4KSA A;  3SCE A;  4KSF A;  4L3Y A;  4XVX A;  1X91 A;  1FS9 A;  1JQI A;  1S26 A;  2A1T A;  3X0Y A;  5B6B A;  5BRM A;  3GQT A;  3C3L A;  2VIG A;  3MMO A;  1XFY A;  4ZXV A;  3C2P A;  3Q22 A;  2GBB A;  2XS1 A;  2YGW A;  2FON A;  2YYI A;  4X28 A;  3OIB A;  4MPE A;  4FF1 A;  4FF3 A;  4O5M A;  4P79 A;  3Q0A A;  2E81 A;  2UXW A;  1IS2 A;  3UU9 A;  1Y8N A;  1XFX A;  3OWM A;  2C12 A;  4AKH A;  4N5F A;  1YRT A;  1RX0 A;  4QIC A;  3D2R A;  2EC5 A;  2ZDX A;  4E00 A;  1UDY A;  5M4M A;  2VF1 A;  3TZ5 A;  1SC5 A;  2BU7 A;  2BU5 A;  3N0R A; 
#chains in the Genus database with same CATH homology
 1K93 A;  4AKI A;  1XFV A;  4AI6 A;  2AZE A;  1RP3 A;  4HKS A;  3CE2 A;  4F0X A;  3Q24 A;  2LFW A;  3C46 A;  1YRU A;  4AKG A;  1PK0 A;  4KSA A;  3KML A;  4KSF A;  1S26 A;  1XFW A;  2AO2 A;  4KS9 A;  4FF4 A;  2QR4 A;  1K8T A;  2EBH X;  2FP2 A;  3C3L A;  1XFY A;  1LVC A;  3C2P A;  4HKR A;  5GJV E;  3Q22 A;  2GBB A;  2YGW A;  4FF2 A;  5GJW E;  1YRT A;  2FP1 A;  2COL A;  4FF3 A;  3VKH A;  4P79 A;  3X29 A;  3Q0A A;  3VKG A;  1Y0V A;  1XFZ A;  1XFX A;  2F6L A;  2PO4 A;  4G97 A;  4AKH A;  2EBF X;  4QIC A;  2EC5 A;  1K90 A;  1SK6 A;  1XFU A;  2VF1 A;  4FZ4 A;  1ZOT A;  3Q23 A;  1SC5 A;  4FF1 A;  3N0R A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1K90A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations