1UKWA

Crystal structure of medium-chain acyl-coa dehydrogenase from thermus thermophilus hb8
Total Genus 148
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
148
sequence length
379
structure length
379
Chain Sequence
b'IDFSLTEEQRQLQALARRFAKEVILPVAQEYDEKEEVPWPVIEKLHEVGLLNAIIPEEYGGMGLKMLDEVIVGEELAYACMGIYTIPMASDLGITPVLLAGTEEQKERFLRPLTEKPALAAFALSEPGNGSDAAALKTRAIRQGDHYVLNGTKMWISNGGEAEWVVVFATVNPELRHKGVVALVVERGTPGFKAIKIHGKMGQRASGTYELVFEDVKVPVENRLGEEGEGFKIAMQTLNKTRIPVAAGSVGVARRALDEARKYAKEREAFGEPIANFQAIQFKLVDMLIGIETARMYTYYAAWLADQGLPHAHASAIAKAYASEIAFEAANQAIQIHGGYGYVREFPVEKLLRDVKLNQIYEGTNEIQRLIIARHILAA'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords acyl-CoA dehydrogenase
publication title Crystal structure of Thermus thermophilus medium-chain acyl-CoA dehydrogenase
rcsb
source organism Thermus thermophilus
molecule tags Oxidoreductase
total genus 148
structure length 379
sequence length 379
chains with identical sequence B
ec nomenclature ec 1.3.99.3: Transferred entry: 1.3.8.7, 1.3.8.8 and 1.3.8.9.
pdb deposition date 2003-09-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 1ukwA01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 1ukwA03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 1ukwA02
3FO3A 3GM6A 4X28A 2UXWA 4Q1OA 3RKHA 2YYJA 3P4TA 2IX6A 3MDEA 4X28C 3GQTA 3MPJA 2ZO5A 3M9VA 3EOMA 2JBTA 4NXLA 5K3JA 4ZYJA 1W07A 2JIFA 2J7AA 1R2JA 1QDBA 3L1TA 1EGEA 4G5EA 2DDHA 3D9FA 1SIRA 2Z1QA 2PG0A 1EGDA 1WS9A 3OWAA 3HWCA 4W9UA 2CX9A 4L3XA 2WBIA 3D6BA 3OWMA 5K3HA 1JQIA 2ZAFA 2REHA 4KTOA 4Q17A 1OAHA 2R0MA 4L3ZA 1U8VA 1RX0A 3SWOA 1FS9A 2JBRA 2YYLA 2E81A 3FCJA 1UDYA 4IRNA 2RDZA 2JBSA 3R7KA 2EBAA 3TORA 3MMOA 2D29A 4DOYA 4P13A 3BNJA 4WJYA 2YYGA 3AFEA 2YYIA 3NF4A 5K3IA 3MXLA 3UU9A 2RFQA 1GU6A 4JEKA 2C12A 2IX5A 4Q5BA 1T9GA 3PFDA 2E80A 3SF6A 3LG1A 3D1IA 3SXQA 4IV6A 3AFFA 2YYKA 2FONA 3SCEA 2C0UA 4ZXVA 3EONA 3D9GA 2VR0A 4HR3A 4U83A 3D9DA 3MDDA 3B96A 4L1FA 2OR0A 4OO2A 1IVHA 2RF7A 3TTBA 4M9AA 3BNGA 4L38A 3LGQA 3D9EA 3BNFA 3OIBA 1UKWA 3X0YA 1BUCA 3GNCA 4Q4UA 4KCFA 2VIGA 3BNHA 4L3YA 4Q5CA 3II9A 3MPIA 3UBRA 2R0NA 2OT4A 1FS8A 1SIQA 2YYMA 4O5MA 2A1TA 1FS7A 3F29A 3X0XA 4RM7A 3S7WA 4XVXA 2DVLA 4Q0TA 1EGCA 5K3GA 3MKHA 4N5FA 1IS2A
chains in the Genus database with same CATH superfamily
4H7QA 3FO3A 4FF4A 3GM6A 4X28A 4MP2A 4MPEA 1XFUA 2UXWA 2EBHX 4Q1OA 3RKHA 2YYJA 3P4TA 2IX6A 3MDEA 1X8ZA 2VF1A 1LVCA 1R3BA 1XFZA 2FP2A 4HKRA 5M4PA 2PNRA 5M4MA 4X28C 3GQTA 2CJ4A 2R02A 5GJVE 4E01A 4AKIA 3MPJA 4KSFA 2ZO5A 2EBFX 3M9VA 3EOMA 2JBTA 4NXLA 5K3JA 4ZYJA 1S26A 4H81A 5B5WA 1W07A 2JIFA 2J7AA 3TZ5A 2BU2A 1R2JA 1QDBA 3L1TA 3C3LA 1XFVA 1EGEA 4G5EA 2DDHA 3D9FA 4MPNA 1PK0A 1XFWA 2Q8FA 5EZ3A 2XQRB 1SIRA 4H85A 5B6BA 2Z1QA 2PG0A 2BTZA 1EGDA 1WS9A 2R03A 3OWAA 3HWCA 4W9UA 2CX9A 4L3XA 2WBIA 3D6BA 2EC5A 3OWMA 5M4NA 5K3HA 1XFYA 1JQIA 2ZAFA 2FP1A 2OEXA 2REHA 4KTOA 4Q17A 3N0RA 3Q22A 1OAHA 2R0MA 4L3ZA 1U8VA 1K8TA 1RJ1A 1X91A 1Y8PA 2CJ6A 2Q8IA 1RX0A 3SWOA 1FS9A 3CE2A 3VKGA 2JBRA 2CJ8A 2PO4A 2YYLA 2E81A 3FCJA 1UDYA 2OJQA 4IRNA 3KMLA 5BRKA 2AZEA 2BU8A 1Y0VA 2AO2A 3U33A 1K90A 2CJ7A 2RDZA 2JBSA 2LFWA 3R7KA 4KSAA 1RJ4A 2EBAA 3TORA 1GKZA 3Q23A 1GKXA 3MMOA 2D29A 4DOYA 3Q24A 3CRKA 4P13A 2R05A 4AKHA 5BRMA 3BNJA 3DJLA 4WJYA 2YYGA 3AFEA 2YYIA 4FF2A 3NF4A 5K3IA 3MXLA 3D2RA 4V26A 2RFQA 3UU9A 1GU6A 4JEKA 4MP7A 2C12A 1X90A 4MPCA 2QR4A 4FF3A 2IX5A 5B5VA 4Q5BA 1T9GA 3PFDA 2E80A 3SF6A 3LG1A 4HKSA 3D1IA 2Q8GA 2XS8A 3SXQA 4IV6A 3AFFA 2YYKA 2FONA 3SCEA 2C0UA 4ZXVA 1K93A 2Q8HA 4QICA 3EONA 4F0XA 3D9GA 1PI1A 1Y8OA 4FZ4A 2VR0A 4J1VA 4LQQB 4HR3A 4U83A 3D9DA 3MDDA 4KS9A 5J71A 3B96A 1RP3A 4L1FA 2E0AA 2ZDXA 2OR0A 2ZKJA 1JM6A 5M4KA 4OO2A 1Y8NA 1IVHA 2RF7A 3TTBA 4M9AA 4FF1A 4AKGA 3BNGA 2F6LA 4L38A 3LGQA 3D9EA 2ZDYA 3BNFA 3Q0AA 4AI6A 1XG2B 1XFXA 4DZYA 3OIBA 1UKWA 3X0YA 4V25A 1BUCA 3GNCA 4Q4UA 4KCFA 3TZ0A 3CRLA 3TZ2A 3C2PA 2OEVA 2VIGA 3BNHA 4L3YA 2XS1A 4Q5CA 2BU5A 3II9A 3MPIA 3UBRA 2CJ5A 2R0NA 2HJNA 4JIZA 4LQSB 4E00A 2OT4A 1FS8A 5J6AA 2BU6A 3X29A 1SIQA 2YYMA 3TZ4A 4O5MA 4E02A 4JIOA 2A1TA 1FS7A 1GJVA 3F29A 3X0XA 4G97A 4RM7A 1SC5A 3VKHA 3S7WA 4XVXA 2DVLA 4P79A 3VADA 4Q0TA 2GBBA 2BU7A 1EGCA 5K3GA 2YGWA 5GJWE 3MKHA 1SK6A 3C46A 4N5FA 1IS2A
chains in the Genus database with same CATH topology
3FO3A 3GM6A 4X28A 2UXWA 4Q1OA 3RKHA 2YYJA 3P4TA 2IX6A 3MDEA 4X28C 3GQTA 3MPJA 2ZO5A 3M9VA 3EOMA 2JBTA 4NXLA 5K3JA 4ZYJA 1W07A 2JIFA 2J7AA 1R2JA 1QDBA 3L1TA 1EGEA 4G5EA 2DDHA 3D9FA 1SIRA 2Z1QA 2PG0A 1EGDA 1WS9A 3OWAA 3HWCA 4W9UA 2CX9A 4L3XA 2WBIA 3D6BA 3OWMA 5K3HA 1JQIA 2ZAFA 2REHA 4KTOA 4Q17A 1OAHA 2R0MA 4L3ZA 1U8VA 1RX0A 3SWOA 1FS9A 2JBRA 2YYLA 2E81A 3FCJA 1UDYA 4IRNA 2RDZA 2JBSA 3R7KA 2EBAA 3TORA 3MMOA 2D29A 4DOYA 4P13A 3BNJA 4WJYA 2YYGA 3AFEA 2YYIA 3NF4A 5K3IA 3MXLA 3UU9A 2RFQA 1GU6A 4JEKA 2C12A 2IX5A 4Q5BA 1T9GA 3PFDA 2E80A 3SF6A 3LG1A 3D1IA 3SXQA 4IV6A 3AFFA 2YYKA 2FONA 3SCEA 2C0UA 4ZXVA 3EONA 3D9GA 2VR0A 4HR3A 4U83A 3D9DA 3MDDA 3B96A 4L1FA 2OR0A 4OO2A 1IVHA 2RF7A 3TTBA 4M9AA 3BNGA 4L38A 3LGQA 3D9EA 3BNFA 3OIBA 1UKWA 3X0YA 1BUCA 3GNCA 4Q4UA 4KCFA 2VIGA 3BNHA 4L3YA 4Q5CA 3II9A 3MPIA 3UBRA 2R0NA 2OT4A 1FS8A 1SIQA 2YYMA 4O5MA 2A1TA 1FS7A 3F29A 3X0XA 4RM7A 3S7WA 4XVXA 2DVLA 4Q0TA 1EGCA 5K3GA 3MKHA 4N5FA 1IS2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FO3 A;  3GM6 A;  4X28 A;  2UXW A;  4Q1O A;  3RKH A;  2YYJ A;  3P4T A;  2IX6 A;  3MDE A;  4X28 C;  3GQT A;  3MPJ A;  2ZO5 A;  3M9V A;  3EOM A;  2JBT A;  4NXL A;  5K3J A;  4ZYJ A;  1W07 A;  2JIF A;  2J7A A;  1R2J A;  1QDB A;  3L1T A;  1EGE A;  4G5E A;  2DDH A;  3D9F A;  1SIR A;  2Z1Q A;  2PG0 A;  1EGD A;  1WS9 A;  3OWA A;  3HWC A;  4W9U A;  2CX9 A;  4L3X A;  2WBI A;  3D6B A;  3OWM A;  5K3H A;  1JQI A;  2ZAF A;  2REH A;  4KTO A;  4Q17 A;  1OAH A;  2R0M A;  4L3Z A;  1U8V A;  1RX0 A;  3SWO A;  1FS9 A;  2JBR A;  2YYL A;  2E81 A;  3FCJ A;  1UDY A;  4IRN A;  2RDZ A;  2JBS A;  3R7K A;  2EBA A;  3TOR A;  3MMO A;  2D29 A;  4DOY A;  4P13 A;  3BNJ A;  4WJY A;  2YYG A;  3AFE A;  2YYI A;  3NF4 A;  5K3I A;  3MXL A;  3UU9 A;  2RFQ A;  1GU6 A;  4JEK A;  2C12 A;  2IX5 A;  4Q5B A;  1T9G A;  3PFD A;  2E80 A;  3SF6 A;  3LG1 A;  3D1I A;  3SXQ A;  4IV6 A;  3AFF A;  2YYK A;  2FON A;  3SCE A;  2C0U A;  4ZXV A;  3EON A;  3D9G A;  2VR0 A;  4HR3 A;  4U83 A;  3D9D A;  3MDD A;  3B96 A;  4L1F A;  2OR0 A;  4OO2 A;  1IVH A;  2RF7 A;  3TTB A;  4M9A A;  3BNG A;  4L38 A;  3LGQ A;  3D9E A;  3BNF A;  3OIB A;  1UKW A;  3X0Y A;  1BUC A;  3GNC A;  4Q4U A;  4KCF A;  2VIG A;  3BNH A;  4L3Y A;  4Q5C A;  3II9 A;  3MPI A;  3UBR A;  2R0N A;  2OT4 A;  1FS8 A;  1SIQ A;  2YYM A;  4O5M A;  2A1T A;  1FS7 A;  3F29 A;  3X0X A;  4RM7 A;  3S7W A;  4XVX A;  2DVL A;  4Q0T A;  1EGC A;  5K3G A;  3MKH A;  4N5F A;  1IS2 A; 
#chains in the Genus database with same CATH topology
 4H7Q A;  3FO3 A;  4FF4 A;  3GM6 A;  4X28 A;  4MP2 A;  4MPE A;  1XFU A;  2UXW A;  2EBH X;  4Q1O A;  3RKH A;  2YYJ A;  3P4T A;  2IX6 A;  3MDE A;  1X8Z A;  2VF1 A;  1LVC A;  1R3B A;  1XFZ A;  2FP2 A;  4HKR A;  5M4P A;  2PNR A;  5M4M A;  4X28 C;  3GQT A;  2CJ4 A;  2R02 A;  5GJV E;  4E01 A;  4AKI A;  3MPJ A;  4KSF A;  2ZO5 A;  2EBF X;  3M9V A;  3EOM A;  2JBT A;  4NXL A;  5K3J A;  4ZYJ A;  1S26 A;  4H81 A;  5B5W A;  1W07 A;  2JIF A;  2J7A A;  3TZ5 A;  2BU2 A;  1R2J A;  1QDB A;  3L1T A;  3C3L A;  1XFV A;  1EGE A;  4G5E A;  2DDH A;  3D9F A;  4MPN A;  1PK0 A;  1XFW A;  2Q8F A;  5EZ3 A;  2XQR B;  1SIR A;  4H85 A;  5B6B A;  2Z1Q A;  2PG0 A;  2BTZ A;  1EGD A;  1WS9 A;  2R03 A;  3OWA A;  3HWC A;  4W9U A;  2CX9 A;  4L3X A;  2WBI A;  3D6B A;  2EC5 A;  3OWM A;  5M4N A;  5K3H A;  1XFY A;  1JQI A;  2ZAF A;  2FP1 A;  2OEX A;  2REH A;  4KTO A;  4Q17 A;  3N0R A;  3Q22 A;  1OAH A;  2R0M A;  4L3Z A;  1U8V A;  1K8T A;  1RJ1 A;  1X91 A;  1Y8P A;  2CJ6 A;  2Q8I A;  1RX0 A;  3SWO A;  1FS9 A;  3CE2 A;  3VKG A;  2JBR A;  2CJ8 A;  2PO4 A;  2YYL A;  2E81 A;  3FCJ A;  1UDY A;  2OJQ A;  4IRN A;  3KML A;  5BRK A;  2AZE A;  2BU8 A;  1Y0V A;  2AO2 A;  3U33 A;  1K90 A;  2CJ7 A;  2RDZ A;  2JBS A;  2LFW A;  3R7K A;  4KSA A;  1RJ4 A;  2EBA A;  3TOR A;  1GKZ A;  3Q23 A;  1GKX A;  3MMO A;  2D29 A;  4DOY A;  3Q24 A;  3CRK A;  4P13 A;  2R05 A;  4AKH A;  5BRM A;  3BNJ A;  3DJL A;  4WJY A;  2YYG A;  3AFE A;  2YYI A;  4FF2 A;  3NF4 A;  5K3I A;  3MXL A;  3D2R A;  4V26 A;  2RFQ A;  3UU9 A;  1GU6 A;  4JEK A;  4MP7 A;  2C12 A;  1X90 A;  4MPC A;  2QR4 A;  4FF3 A;  2IX5 A;  5B5V A;  4Q5B A;  1T9G A;  3PFD A;  2E80 A;  3SF6 A;  3LG1 A;  4HKS A;  3D1I A;  2Q8G A;  2XS8 A;  3SXQ A;  4IV6 A;  3AFF A;  2YYK A;  2FON A;  3SCE A;  2C0U A;  4ZXV A;  1K93 A;  2Q8H A;  4QIC A;  3EON A;  4F0X A;  3D9G A;  1PI1 A;  1Y8O A;  4FZ4 A;  2VR0 A;  4J1V A;  4LQQ B;  4HR3 A;  4U83 A;  3D9D A;  3MDD A;  4KS9 A;  5J71 A;  3B96 A;  1RP3 A;  4L1F A;  2E0A A;  2ZDX A;  2OR0 A;  2ZKJ A;  1JM6 A;  5M4K A;  4OO2 A;  1Y8N A;  1IVH A;  2RF7 A;  3TTB A;  4M9A A;  4FF1 A;  4AKG A;  3BNG A;  2F6L A;  4L38 A;  3LGQ A;  3D9E A;  2ZDY A;  3BNF A;  3Q0A A;  4AI6 A;  1XG2 B;  1XFX A;  4DZY A;  3OIB A;  1UKW A;  3X0Y A;  4V25 A;  1BUC A;  3GNC A;  4Q4U A;  4KCF A;  3TZ0 A;  3CRL A;  3TZ2 A;  3C2P A;  2OEV A;  2VIG A;  3BNH A;  4L3Y A;  2XS1 A;  4Q5C A;  2BU5 A;  3II9 A;  3MPI A;  3UBR A;  2CJ5 A;  2R0N A;  2HJN A;  4JIZ A;  4LQS B;  4E00 A;  2OT4 A;  1FS8 A;  5J6A A;  2BU6 A;  3X29 A;  1SIQ A;  2YYM A;  3TZ4 A;  4O5M A;  4E02 A;  4JIO A;  2A1T A;  1FS7 A;  1GJV A;  3F29 A;  3X0X A;  4G97 A;  4RM7 A;  1SC5 A;  3VKH A;  3S7W A;  4XVX A;  2DVL A;  4P79 A;  3VAD A;  4Q0T A;  2GBB A;  2BU7 A;  1EGC A;  5K3G A;  2YGW A;  5GJW E;  3MKH A;  1SK6 A;  3C46 A;  4N5F A;  1IS2 A; 
#chains in the Genus database with same CATH homology
 3FO3 A;  3GM6 A;  4X28 A;  2UXW A;  4Q1O A;  3RKH A;  2YYJ A;  3P4T A;  2IX6 A;  3MDE A;  4X28 C;  3GQT A;  3MPJ A;  2ZO5 A;  3M9V A;  3EOM A;  2JBT A;  4NXL A;  5K3J A;  4ZYJ A;  1W07 A;  2JIF A;  2J7A A;  1R2J A;  1QDB A;  3L1T A;  1EGE A;  4G5E A;  2DDH A;  3D9F A;  1SIR A;  2Z1Q A;  2PG0 A;  1EGD A;  1WS9 A;  3OWA A;  3HWC A;  4W9U A;  2CX9 A;  4L3X A;  2WBI A;  3D6B A;  3OWM A;  5K3H A;  1JQI A;  2ZAF A;  2REH A;  4KTO A;  4Q17 A;  1OAH A;  2R0M A;  4L3Z A;  1U8V A;  1RX0 A;  3SWO A;  1FS9 A;  2JBR A;  2YYL A;  2E81 A;  3FCJ A;  1UDY A;  4IRN A;  2RDZ A;  2JBS A;  3R7K A;  2EBA A;  3TOR A;  3MMO A;  2D29 A;  4DOY A;  4P13 A;  3BNJ A;  4WJY A;  2YYG A;  3AFE A;  2YYI A;  3NF4 A;  5K3I A;  3MXL A;  3UU9 A;  2RFQ A;  1GU6 A;  4JEK A;  2C12 A;  2IX5 A;  4Q5B A;  1T9G A;  3PFD A;  2E80 A;  3SF6 A;  3LG1 A;  3D1I A;  3SXQ A;  4IV6 A;  3AFF A;  2YYK A;  2FON A;  3SCE A;  2C0U A;  4ZXV A;  3EON A;  3D9G A;  2VR0 A;  4HR3 A;  4U83 A;  3D9D A;  3MDD A;  3B96 A;  4L1F A;  2OR0 A;  4OO2 A;  1IVH A;  2RF7 A;  3TTB A;  4M9A A;  3BNG A;  4L38 A;  3LGQ A;  3D9E A;  3BNF A;  3OIB A;  1UKW A;  3X0Y A;  1BUC A;  3GNC A;  4Q4U A;  4KCF A;  2VIG A;  3BNH A;  4L3Y A;  4Q5C A;  3II9 A;  3MPI A;  3UBR A;  2R0N A;  2OT4 A;  1FS8 A;  1SIQ A;  2YYM A;  4O5M A;  2A1T A;  1FS7 A;  3F29 A;  3X0X A;  4RM7 A;  3S7W A;  4XVX A;  2DVL A;  4Q0T A;  1EGC A;  5K3G A;  3MKH A;  4N5F A;  1IS2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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