1UKWA

Crystal structure of medium-chain acyl-coa dehydrogenase from thermus thermophilus hb8
Total Genus 148
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
148
sequence length
379
structure length
379
Chain Sequence
IDFSLTEEQRQLQALARRFAKEVILPVAQEYDEKEEVPWPVIEKLHEVGLLNAIIPEEYGGMGLKMLDEVIVGEELAYACMGIYTIPMASDLGITPVLLAGTEEQKERFLRPLTEKPALAAFALSEPGNGSDAAALKTRAIRQGDHYVLNGTKMWISNGGEAEWVVVFATVNPELRHKGVVALVVERGTPGFKAIKIHGKMGQRASGTYELVFEDVKVPVENRLGEEGEGFKIAMQTLNKTRIPVAAGSVGVARRALDEARKYAKEREAFGEPIANFQAIQFKLVDMLIGIETARMYTYYAAWLADQGLPHAHASAIAKAYASEIAFEAANQAIQIHGGYGYVREFPVEKLLRDVKLNQIYEGTNEIQRLIIARHILAA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords acyl-CoA dehydrogenase
publication title Crystal structure of Thermus thermophilus medium-chain acyl-CoA dehydrogenase
rcsb
source organism Thermus thermophilus
molecule tags Oxidoreductase
total genus 148
structure length 379
sequence length 379
chains with identical sequence B
ec nomenclature ec 1.3.99.3: Transferred entry: 1.3.8.7, 1.3.8.8 and 1.3.8.9.
pdb deposition date 2003-09-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 1ukwA01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 1ukwA03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 1ukwA02
4P13A 3SWOA 4Q17A 4L3YA 3D9FA 3HWCA 1EGEA 3NF4A 2IX5A 4Q0TA 3D9EA 3MXLA 1R2JA 3MDDA 1FS9A 2RDZA 1GU6A 4Q5BA 2ZAFA 2D29A 3BNHA 2OT4A 3II9A 3EONA 2UXWA 3D9GA 4IRNA 3RKHA 2CX9A 3F29A 3MMOA 1IS2A 4X28A 2R0MA 4G5EA 4Q4UA 1W07A 3OWMA 3B96A 4Q1OA 1FS7A 4DOYA 2C0UA 2DVLA 1UDYA 2YYJA 4KTOA 3MPIA 3LGQA 2DDHA 2JBTA 4HR3A 2VIGA 3AFFA 3SF6A 2C12A 4WJYA 5K3GA 5K3HA 5K3IA 2YYIA 1U8VA 2J7AA 3SXQA 3GQTA 2YYMA 2WBIA 4U83A 2E81A 3LG1A 4KCFA 4M9AA 4Q5CA 1RX0A 2YYGA 2IX6A 3MKHA 1T9GA 1QDBA 3S7WA 1IVHA 1UKWA 3SCEA 1SIQA 2JBSA 3MPJA 3UU9A 3AFEA 4L1FA 3TORA 4L3ZA 1EGCA 2R0NA 3BNJA 4OO2A 5K3JA 4XVXA 3PFDA 3D6BA 3FO3A 3MDEA 4L38A 1FS8A 1JQIA 4JEKA 3FCJA 3OWAA 2VR0A 4IV6A 3P4TA 4ZXVA 3D9DA 2Z1QA 2E80A 2RF7A 3UBRA 2JBRA 3BNFA 2PG0A 2A1TA 2YYLA 4NXLA 4X28C 2EBAA 1EGDA 2OR0A 1SIRA 3OIBA 1WS9A 2RFQA 2ZO5A 2REHA 2FONA 4N5FA 2YYKA 4O5MA 4L3XA 3TTBA 3M9VA 3X0XA 2JIFA 3BNGA 3EOMA 1BUCA 4W9UA 4ZYJA 3L1TA 3R7KA 3GNCA 4RM7A 3D1IA 3X0YA 1OAHA 3GM6A
chains in the Genus database with same CATH superfamily
4P13A 3SWOA 1X91A 1RJ4A 4L3YA 4Q17A 5BRKA 3D9FA 2R02A 3HWCA 2PNRA 5BRMA 1RJ1A 1EGEA 3NF4A 2IX5A 1R3BA 2EC5A 2CJ8A 1JM6A 1XFZA 2EBFX 4Q0TA 4FF3A 3D9EA 3MXLA 1R2JA 3MDDA 1FS9A 2OJQA 2RDZA 1GU6A 1XFXA 2OEVA 4LQSB 2ZAFA 4Q5BA 3C2PA 2D29A 1Y8OA 3BNHA 2OT4A 3II9A 3EONA 2UXWA 3U33A 3D9GA 4IRNA 3RKHA 2CX9A 3F29A 3MMOA 1IS2A 4X28A 3CRLA 2R0MA 4G5EA 1XFYA 1W07A 4Q4UA 3OWMA 3B96A 2ZDYA 3KMLA 4Q1OA 1FS7A 2BU2A 4DOYA 2C0UA 2DVLA 1UDYA 2YYJA 4KTOA 1X8ZA 2YGWA 4E02A 3MPIA 3LGQA 2DDHA 2BU5A 2CJ5A 4J1VA 2JBTA 4HR3A 2QR4A 4MPNA 2EBHX 2VF1A 2VIGA 4H7QA 4E01A 3AFFA 3SF6A 2C12A 2CJ4A 5K3GA 2CJ7A 2FP2A 5K3HA 5K3IA 2R05A 4WJYA 2E0AA 3Q24A 3N0RA 3C3LA 2YYIA 2FP1A 1Y8NA 1PI1A 1U8VA 2J7AA 2AO2A 2XQRB 4MPCA 5GJVE 3GQTA 2YYMA 3SXQA 4LQQB 2WBIA 4U83A 2E81A 3TZ2A 3VKHA 2XS1A 5M4NA 3LG1A 2BTZA 4KCFA 4M9AA 1Y8PA 3CRKA 1K90A 5M4PA 3C46A 4Q5CA 3VKGA 1RX0A 2YYGA 2IX6A 1XFWA 4KSAA 3Q0AA 5M4MA 2Q8GA 3MKHA 4QICA 1PK0A 1T9GA 1QDBA 3S7WA 4G97A 1IVHA 1SC5A 3DJLA 4HKRA 4H85A 4KS9A 1UKWA 1XFVA 1GKXA 3CE2A 4MPEA 3SCEA 5B5VA 1SIQA 2JBSA 3MPJA 2OEXA 3AFEA 3TZ5A 3TZ0A 3UU9A 2BU6A 3X29A 4L1FA 2Q8IA 3VADA 2BU7A 4L3ZA 3TORA 1EGCA 4FF4A 2GBBA 1SK6A 1LVCA 2R0NA 1GKZA 1K8TA 5B5WA 5J71A 2XS8A 3BNJA 4OO2A 5K3JA 4XVXA 4FZ4A 5J6AA 3PFDA 3D6BA 4HKSA 3FO3A 3MDEA 4L38A 2R03A 1FS8A 1JQIA 4E00A 2LFWA 4JEKA 3FCJA 4V25A 3OWAA 1GJVA 5GJWE 5B6BA 2VR0A 4IV6A 4FF2A 3P4TA 4ZXVA 1X90A 1Y0VA 4KSFA 3D9DA 2Q8HA 2Z1QA 4AKGA 5EZ3A 2E80A 2RF7A 3UBRA 2JBRA 4MP2A 3BNFA 2PG0A 4AKIA 2ZKJA 4H81A 4JIZA 3Q22A 1XFUA 2A1TA 2YYLA 4AKHA 4NXLA 4X28C 2EBAA 1EGDA 2OR0A 2PO4A 1SIRA 3Q23A 3OIBA 1WS9A 2RFQA 2ZO5A 2REHA 1RP3A 2FONA 2AZEA 4N5FA 4FF1A 2YYKA 4F0XA 4O5MA 2ZDXA 4L3XA 3M9VA 2BU8A 2CJ6A 3X0XA 2HJNA 3TTBA 1S26A 3TZ4A 2F6LA 2JIFA 3BNGA 5M4KA 4V26A 3EOMA 1BUCA 4W9UA 4MP7A 4DZYA 4AI6A 4ZYJA 1XG2B 3L1TA 3R7KA 3GNCA 4RM7A 3D1IA 3X0YA 1OAHA 4P79A 2Q8FA 1K93A 4JIOA 3GM6A 3D2RA
chains in the Genus database with same CATH topology
4P13A 3SWOA 4Q17A 4L3YA 3D9FA 3HWCA 1EGEA 3NF4A 2IX5A 4Q0TA 3D9EA 3MXLA 1R2JA 3MDDA 1FS9A 2RDZA 1GU6A 4Q5BA 2ZAFA 2D29A 3BNHA 2OT4A 3II9A 3EONA 2UXWA 3D9GA 4IRNA 3RKHA 2CX9A 3F29A 3MMOA 1IS2A 4X28A 2R0MA 4G5EA 4Q4UA 1W07A 3OWMA 3B96A 4Q1OA 1FS7A 4DOYA 2C0UA 2DVLA 1UDYA 2YYJA 4KTOA 3MPIA 3LGQA 2DDHA 2JBTA 4HR3A 2VIGA 3AFFA 3SF6A 2C12A 4WJYA 5K3GA 5K3HA 5K3IA 2YYIA 1U8VA 2J7AA 3SXQA 3GQTA 2YYMA 2WBIA 4U83A 2E81A 3LG1A 4KCFA 4M9AA 4Q5CA 1RX0A 2YYGA 2IX6A 3MKHA 1T9GA 1QDBA 3S7WA 1IVHA 1UKWA 3SCEA 1SIQA 2JBSA 3MPJA 3UU9A 3AFEA 4L1FA 3TORA 4L3ZA 1EGCA 2R0NA 3BNJA 4OO2A 5K3JA 4XVXA 3PFDA 3D6BA 3FO3A 3MDEA 4L38A 1FS8A 1JQIA 4JEKA 3FCJA 3OWAA 2VR0A 4IV6A 3P4TA 4ZXVA 3D9DA 2Z1QA 2E80A 2RF7A 3UBRA 2JBRA 3BNFA 2PG0A 2A1TA 2YYLA 4NXLA 4X28C 2EBAA 1EGDA 2OR0A 1SIRA 3OIBA 1WS9A 2RFQA 2ZO5A 2REHA 2FONA 4N5FA 2YYKA 4O5MA 4L3XA 3TTBA 3M9VA 3X0XA 2JIFA 3BNGA 3EOMA 1BUCA 4W9UA 4ZYJA 3L1TA 3R7KA 3GNCA 4RM7A 3D1IA 3X0YA 1OAHA 3GM6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P13 A;  3SWO A;  4Q17 A;  4L3Y A;  3D9F A;  3HWC A;  1EGE A;  3NF4 A;  2IX5 A;  4Q0T A;  3D9E A;  3MXL A;  1R2J A;  3MDD A;  1FS9 A;  2RDZ A;  1GU6 A;  4Q5B A;  2ZAF A;  2D29 A;  3BNH A;  2OT4 A;  3II9 A;  3EON A;  2UXW A;  3D9G A;  4IRN A;  3RKH A;  2CX9 A;  3F29 A;  3MMO A;  1IS2 A;  4X28 A;  2R0M A;  4G5E A;  4Q4U A;  1W07 A;  3OWM A;  3B96 A;  4Q1O A;  1FS7 A;  4DOY A;  2C0U A;  2DVL A;  1UDY A;  2YYJ A;  4KTO A;  3MPI A;  3LGQ A;  2DDH A;  2JBT A;  4HR3 A;  2VIG A;  3AFF A;  3SF6 A;  2C12 A;  4WJY A;  5K3G A;  5K3H A;  5K3I A;  2YYI A;  1U8V A;  2J7A A;  3SXQ A;  3GQT A;  2YYM A;  2WBI A;  4U83 A;  2E81 A;  3LG1 A;  4KCF A;  4M9A A;  4Q5C A;  1RX0 A;  2YYG A;  2IX6 A;  3MKH A;  1T9G A;  1QDB A;  3S7W A;  1IVH A;  1UKW A;  3SCE A;  1SIQ A;  2JBS A;  3MPJ A;  3UU9 A;  3AFE A;  4L1F A;  3TOR A;  4L3Z A;  1EGC A;  2R0N A;  3BNJ A;  4OO2 A;  5K3J A;  4XVX A;  3PFD A;  3D6B A;  3FO3 A;  3MDE A;  4L38 A;  1FS8 A;  1JQI A;  4JEK A;  3FCJ A;  3OWA A;  2VR0 A;  4IV6 A;  3P4T A;  4ZXV A;  3D9D A;  2Z1Q A;  2E80 A;  2RF7 A;  3UBR A;  2JBR A;  3BNF A;  2PG0 A;  2A1T A;  2YYL A;  4NXL A;  4X28 C;  2EBA A;  1EGD A;  2OR0 A;  1SIR A;  3OIB A;  1WS9 A;  2RFQ A;  2ZO5 A;  2REH A;  2FON A;  4N5F A;  2YYK A;  4O5M A;  4L3X A;  3TTB A;  3M9V A;  3X0X A;  2JIF A;  3BNG A;  3EOM A;  1BUC A;  4W9U A;  4ZYJ A;  3L1T A;  3R7K A;  3GNC A;  4RM7 A;  3D1I A;  3X0Y A;  1OAH A;  3GM6 A; 
#chains in the Genus database with same CATH topology
 4P13 A;  3SWO A;  1X91 A;  1RJ4 A;  4L3Y A;  4Q17 A;  5BRK A;  3D9F A;  2R02 A;  3HWC A;  2PNR A;  5BRM A;  1RJ1 A;  1EGE A;  3NF4 A;  2IX5 A;  1R3B A;  2EC5 A;  2CJ8 A;  1JM6 A;  1XFZ A;  2EBF X;  4Q0T A;  4FF3 A;  3D9E A;  3MXL A;  1R2J A;  3MDD A;  1FS9 A;  2OJQ A;  2RDZ A;  1GU6 A;  1XFX A;  2OEV A;  4LQS B;  2ZAF A;  4Q5B A;  3C2P A;  2D29 A;  1Y8O A;  3BNH A;  2OT4 A;  3II9 A;  3EON A;  2UXW A;  3U33 A;  3D9G A;  4IRN A;  3RKH A;  2CX9 A;  3F29 A;  3MMO A;  1IS2 A;  4X28 A;  3CRL A;  2R0M A;  4G5E A;  1XFY A;  1W07 A;  4Q4U A;  3OWM A;  3B96 A;  2ZDY A;  3KML A;  4Q1O A;  1FS7 A;  2BU2 A;  4DOY A;  2C0U A;  2DVL A;  1UDY A;  2YYJ A;  4KTO A;  1X8Z A;  2YGW A;  4E02 A;  3MPI A;  3LGQ A;  2DDH A;  2BU5 A;  2CJ5 A;  4J1V A;  2JBT A;  4HR3 A;  2QR4 A;  4MPN A;  2EBH X;  2VF1 A;  2VIG A;  4H7Q A;  4E01 A;  3AFF A;  3SF6 A;  2C12 A;  2CJ4 A;  5K3G A;  2CJ7 A;  2FP2 A;  5K3H A;  5K3I A;  2R05 A;  4WJY A;  2E0A A;  3Q24 A;  3N0R A;  3C3L A;  2YYI A;  2FP1 A;  1Y8N A;  1PI1 A;  1U8V A;  2J7A A;  2AO2 A;  2XQR B;  4MPC A;  5GJV E;  3GQT A;  2YYM A;  3SXQ A;  4LQQ B;  2WBI A;  4U83 A;  2E81 A;  3TZ2 A;  3VKH A;  2XS1 A;  5M4N A;  3LG1 A;  2BTZ A;  4KCF A;  4M9A A;  1Y8P A;  3CRK A;  1K90 A;  5M4P A;  3C46 A;  4Q5C A;  3VKG A;  1RX0 A;  2YYG A;  2IX6 A;  1XFW A;  4KSA A;  3Q0A A;  5M4M A;  2Q8G A;  3MKH A;  4QIC A;  1PK0 A;  1T9G A;  1QDB A;  3S7W A;  4G97 A;  1IVH A;  1SC5 A;  3DJL A;  4HKR A;  4H85 A;  4KS9 A;  1UKW A;  1XFV A;  1GKX A;  3CE2 A;  4MPE A;  3SCE A;  5B5V A;  1SIQ A;  2JBS A;  3MPJ A;  2OEX A;  3AFE A;  3TZ5 A;  3TZ0 A;  3UU9 A;  2BU6 A;  3X29 A;  4L1F A;  2Q8I A;  3VAD A;  2BU7 A;  4L3Z A;  3TOR A;  1EGC A;  4FF4 A;  2GBB A;  1SK6 A;  1LVC A;  2R0N A;  1GKZ A;  1K8T A;  5B5W A;  5J71 A;  2XS8 A;  3BNJ A;  4OO2 A;  5K3J A;  4XVX A;  4FZ4 A;  5J6A A;  3PFD A;  3D6B A;  4HKS A;  3FO3 A;  3MDE A;  4L38 A;  2R03 A;  1FS8 A;  1JQI A;  4E00 A;  2LFW A;  4JEK A;  3FCJ A;  4V25 A;  3OWA A;  1GJV A;  5GJW E;  5B6B A;  2VR0 A;  4IV6 A;  4FF2 A;  3P4T A;  4ZXV A;  1X90 A;  1Y0V A;  4KSF A;  3D9D A;  2Q8H A;  2Z1Q A;  4AKG A;  5EZ3 A;  2E80 A;  2RF7 A;  3UBR A;  2JBR A;  4MP2 A;  3BNF A;  2PG0 A;  4AKI A;  2ZKJ A;  4H81 A;  4JIZ A;  3Q22 A;  1XFU A;  2A1T A;  2YYL A;  4AKH A;  4NXL A;  4X28 C;  2EBA A;  1EGD A;  2OR0 A;  2PO4 A;  1SIR A;  3Q23 A;  3OIB A;  1WS9 A;  2RFQ A;  2ZO5 A;  2REH A;  1RP3 A;  2FON A;  2AZE A;  4N5F A;  4FF1 A;  2YYK A;  4F0X A;  4O5M A;  2ZDX A;  4L3X A;  3M9V A;  2BU8 A;  2CJ6 A;  3X0X A;  2HJN A;  3TTB A;  1S26 A;  3TZ4 A;  2F6L A;  2JIF A;  3BNG A;  5M4K A;  4V26 A;  3EOM A;  1BUC A;  4W9U A;  4MP7 A;  4DZY A;  4AI6 A;  4ZYJ A;  1XG2 B;  3L1T A;  3R7K A;  3GNC A;  4RM7 A;  3D1I A;  3X0Y A;  1OAH A;  4P79 A;  2Q8F A;  1K93 A;  4JIO A;  3GM6 A;  3D2R A; 
#chains in the Genus database with same CATH homology
 4P13 A;  3SWO A;  4Q17 A;  4L3Y A;  3D9F A;  3HWC A;  1EGE A;  3NF4 A;  2IX5 A;  4Q0T A;  3D9E A;  3MXL A;  1R2J A;  3MDD A;  1FS9 A;  2RDZ A;  1GU6 A;  4Q5B A;  2ZAF A;  2D29 A;  3BNH A;  2OT4 A;  3II9 A;  3EON A;  2UXW A;  3D9G A;  4IRN A;  3RKH A;  2CX9 A;  3F29 A;  3MMO A;  1IS2 A;  4X28 A;  2R0M A;  4G5E A;  4Q4U A;  1W07 A;  3OWM A;  3B96 A;  4Q1O A;  1FS7 A;  4DOY A;  2C0U A;  2DVL A;  1UDY A;  2YYJ A;  4KTO A;  3MPI A;  3LGQ A;  2DDH A;  2JBT A;  4HR3 A;  2VIG A;  3AFF A;  3SF6 A;  2C12 A;  4WJY A;  5K3G A;  5K3H A;  5K3I A;  2YYI A;  1U8V A;  2J7A A;  3SXQ A;  3GQT A;  2YYM A;  2WBI A;  4U83 A;  2E81 A;  3LG1 A;  4KCF A;  4M9A A;  4Q5C A;  1RX0 A;  2YYG A;  2IX6 A;  3MKH A;  1T9G A;  1QDB A;  3S7W A;  1IVH A;  1UKW A;  3SCE A;  1SIQ A;  2JBS A;  3MPJ A;  3UU9 A;  3AFE A;  4L1F A;  3TOR A;  4L3Z A;  1EGC A;  2R0N A;  3BNJ A;  4OO2 A;  5K3J A;  4XVX A;  3PFD A;  3D6B A;  3FO3 A;  3MDE A;  4L38 A;  1FS8 A;  1JQI A;  4JEK A;  3FCJ A;  3OWA A;  2VR0 A;  4IV6 A;  3P4T A;  4ZXV A;  3D9D A;  2Z1Q A;  2E80 A;  2RF7 A;  3UBR A;  2JBR A;  3BNF A;  2PG0 A;  2A1T A;  2YYL A;  4NXL A;  4X28 C;  2EBA A;  1EGD A;  2OR0 A;  1SIR A;  3OIB A;  1WS9 A;  2RFQ A;  2ZO5 A;  2REH A;  2FON A;  4N5F A;  2YYK A;  4O5M A;  4L3X A;  3TTB A;  3M9V A;  3X0X A;  2JIF A;  3BNG A;  3EOM A;  1BUC A;  4W9U A;  4ZYJ A;  3L1T A;  3R7K A;  3GNC A;  4RM7 A;  3D1I A;  3X0Y A;  1OAH A;  3GM6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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