1UKWA

Crystal structure of medium-chain acyl-coa dehydrogenase from thermus thermophilus hb8
Total Genus 148
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
148
sequence length
379
structure length
379
Chain Sequence
IDFSLTEEQRQLQALARRFAKEVILPVAQEYDEKEEVPWPVIEKLHEVGLLNAIIPEEYGGMGLKMLDEVIVGEELAYACMGIYTIPMASDLGITPVLLAGTEEQKERFLRPLTEKPALAAFALSEPGNGSDAAALKTRAIRQGDHYVLNGTKMWISNGGEAEWVVVFATVNPELRHKGVVALVVERGTPGFKAIKIHGKMGQRASGTYELVFEDVKVPVENRLGEEGEGFKIAMQTLNKTRIPVAAGSVGVARRALDEARKYAKEREAFGEPIANFQAIQFKLVDMLIGIETARMYTYYAAWLADQGLPHAHASAIAKAYASEIAFEAANQAIQIHGGYGYVREFPVEKLLRDVKLNQIYEGTNEIQRLIIARHILAA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Oxidoreductase
molecule keywords acyl-CoA dehydrogenase
publication title Crystal structure of Thermus thermophilus medium-chain acyl-CoA dehydrogenase
rcsb
source organism Thermus thermophilus
total genus 148
structure length 379
sequence length 379
chains with identical sequence B
ec nomenclature ec 1.3.99.3: Transferred entry: 1.3.8.7, 1.3.8.8 and 1.3.8.9.
pdb deposition date 2003-09-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 1ukwA01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 1ukwA03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 1ukwA02
1UDYA 3B96A 2D29A 3GNCA 4O5MA 2JBRA 4Q17A 4Q1OA 2ZAFA 2RF7A 2JIFA 4DOYA 3D6BA 5K3HA 2VR0A 2OT4A 3X0YA 3P4TA 1U8VA 3D1IA 4Q0TA 3GM6A 3MPIA 3SCEA 4WJYA 3LGQA 3F29A 2CX9A 4HR3A 2OR0A 1RX0A 2R0MA 3D9DA 1FS7A 1SIQA 3X0XA 3BNJA 3MDDA 4W9UA 3LG1A 4IV6A 3OWMA 4X28A 3S7WA 1W07A 3RKHA 4G5EA 5K3GA 1FS8A 2IX5A 2PG0A 2FONA 3BNHA 3OIBA 2EBAA 4L3XA 4RM7A 4Q4UA 2RFQA 2C0UA 4L38A 2YYKA 4U83A 3FO3A 3R7KA 4P13A 1UKWA 2UXWA 2Z1QA 3MPJA 3TTBA 4IRNA 2YYMA 3II9A 1WS9A 4X28C 4M9AA 4KTOA 1QDBA 3HWCA 3AFEA 2YYLA 4XVXA 2C12A 3BNGA 2VIGA 4ZYJA 2IX6A 3L1TA 3SWOA 2JBTA 2R0NA 1R2JA 4Q5BA 1GU6A 4JEKA 2YYGA 1BUCA 3UBRA 1EGDA 2YYIA 4N5FA 4NXLA 3EOMA 3SF6A 1EGEA 3MMOA 1OAHA 3AFFA 3M9VA 4L3ZA 3D9EA 4L3YA 3EONA 2DDHA 2E80A 1EGCA 3D9FA 4L1FA 3UU9A 3SXQA 1T9GA 4ZXVA 3FCJA 1FS9A 3GQTA 3MDEA 3TORA 5K3JA 2YYJA 2JBSA 3MKHA 2WBIA 1IVHA 2E81A 2RDZA 3NF4A 2DVLA 3D9GA 3BNFA 1SIRA 1JQIA 5K3IA 4OO2A 2ZO5A 2A1TA 2REHA 4Q5CA 3PFDA 4KCFA 3MXLA 1IS2A 3OWAA 2J7AA
chains in the Genus database with same CATH superfamily
1UDYA 5B6BA 1R3BA 5B5VA 3B96A 2D29A 3GNCA 4O5MA 2JBRA 4Q17A 1RJ4A 4Q1OA 2ZAFA 2RF7A 2JIFA 3TZ2A 4DOYA 1XFUA 1Y0VA 2XS8A 3D6BA 5K3HA 1SK6A 2ZDYA 2Q8HA 2VR0A 2OT4A 3X0YA 4MPCA 2Q8IA 1X90A 3P4TA 1U8VA 3D1IA 4Q0TA 2Q8FA 2PO4A 3VKGA 3CRKA 3GM6A 1RJ1A 3MPIA 3SCEA 4V25A 3TZ0A 1X8ZA 2PNRA 2ZDXA 4WJYA 3LGQA 2ZKJA 3F29A 2BU7A 4HKSA 3D2RA 2CX9A 4HR3A 2OR0A 1RX0A 2R0MA 3D9DA 1FS7A 1SIQA 3X0XA 3BNJA 3MDDA 4W9UA 3X29A 3LG1A 4IV6A 1XFZA 3U33A 3OWMA 4X28A 4LQSB 3S7WA 3Q0AA 2R03A 1W07A 2YGWA 4MPEA 3RKHA 4G5EA 5K3GA 1FS8A 4LQQB 1S26A 3Q23A 2IX5A 2CJ8A 4AI6A 2R05A 5J6AA 3VKHA 5EZ3A 2PG0A 2FONA 1X91A 5GJVE 3BNHA 5BRKA 1PK0A 4AKGA 2BU2A 3OIBA 2EBAA 4L3XA 4RM7A 4Q4UA 2RFQA 5M4MA 2C0UA 4L38A 2R02A 2F6LA 4U83A 2YYKA 4FF3A 1LVCA 3FO3A 2FP1A 2OJQA 3R7KA 1SC5A 1XFWA 2BU6A 4P13A 5M4NA 4J1VA 1UKWA 2UXWA 1XG2B 2Z1QA 3MPJA 3TTBA 4IRNA 2YYMA 4KS9A 1JM6A 3II9A 1Y8PA 3CE2A 4HKRA 4KSFA 1WS9A 4X28C 2AO2A 4M9AA 4KTOA 4JIZA 1K93A 3TZ5A 1QDBA 3CRLA 3VADA 2XS1A 1GKXA 4FF2A 3HWCA 3AFEA 2YYLA 2XQRB 1GJVA 4XVXA 4MP2A 2CJ7A 3KMLA 4MPNA 3C3LA 1Y8NA 2C12A 2CJ5A 2GBBA 3BNGA 2Q8GA 2VIGA 3Q24A 4ZYJA 3TZ4A 5B5WA 3DJLA 4AKIA 2EBHX 2IX6A 3L1TA 4MP7A 3SWOA 2JBTA 2QR4A 2CJ6A 5M4KA 4E02A 2R0NA 1R2JA 4Q5BA 1GU6A 4DZYA 4JEKA 2YYGA 1BUCA 3UBRA 1EGDA 2EC5A 2HJNA 4N5FA 2YYIA 2FP2A 4G97A 4NXLA 3N0RA 2AZEA 3EOMA 1XFYA 4FZ4A 3SF6A 1EGEA 3MMOA 4P79A 2CJ4A 1OAHA 2E0AA 3AFFA 3M9VA 4H7QA 3Q22A 1XFVA 4L3ZA 5M4PA 3D9EA 4L3YA 4H85A 4E00A 3EONA 2DDHA 2E80A 2OEXA 4KSAA 1EGCA 3D9FA 4L1FA 2BU5A 2OEVA 3UU9A 3SXQA 1T9GA 4ZXVA 3FCJA 1FS9A 3GQTA 1Y8OA 2EBFX 3MDEA 2BTZA 4QICA 3TORA 5K3JA 2YYJA 2JBSA 4H81A 4V26A 5GJWE 3MKHA 4FF4A 2WBIA 1K90A 1IVHA 4F0XA 2E81A 2RDZA 5BRMA 1PI1A 3NF4A 2DVLA 4FF1A 3D9GA 3BNFA 1SIRA 1JQIA 5J71A 5K3IA 1K8TA 2BU8A 2VF1A 2ZO5A 4OO2A 2A1TA 2REHA 1GKZA 4AKHA 4Q5CA 3PFDA 1XFXA 2LFWA 4KCFA 3MXLA 1IS2A 4JIOA 4E01A 3C2PA 3C46A 1RP3A 3OWAA 2J7AA
chains in the Genus database with same CATH topology
1UDYA 3B96A 2D29A 3GNCA 4O5MA 2JBRA 4Q17A 4Q1OA 2ZAFA 2RF7A 2JIFA 4DOYA 3D6BA 5K3HA 2VR0A 2OT4A 3X0YA 3P4TA 1U8VA 3D1IA 4Q0TA 3GM6A 3MPIA 3SCEA 4WJYA 3LGQA 3F29A 2CX9A 4HR3A 2OR0A 1RX0A 2R0MA 3D9DA 1FS7A 1SIQA 3X0XA 3BNJA 3MDDA 4W9UA 3LG1A 4IV6A 3OWMA 4X28A 3S7WA 1W07A 3RKHA 4G5EA 5K3GA 1FS8A 2IX5A 2PG0A 2FONA 3BNHA 3OIBA 2EBAA 4L3XA 4RM7A 4Q4UA 2RFQA 2C0UA 4L38A 2YYKA 4U83A 3FO3A 3R7KA 4P13A 1UKWA 2UXWA 2Z1QA 3MPJA 3TTBA 4IRNA 2YYMA 3II9A 1WS9A 4X28C 4M9AA 4KTOA 1QDBA 3HWCA 3AFEA 2YYLA 4XVXA 2C12A 3BNGA 2VIGA 4ZYJA 2IX6A 3L1TA 3SWOA 2JBTA 2R0NA 1R2JA 4Q5BA 1GU6A 4JEKA 2YYGA 1BUCA 3UBRA 1EGDA 2YYIA 4N5FA 4NXLA 3EOMA 3SF6A 1EGEA 3MMOA 1OAHA 3AFFA 3M9VA 4L3ZA 3D9EA 4L3YA 3EONA 2DDHA 2E80A 1EGCA 3D9FA 4L1FA 3UU9A 3SXQA 1T9GA 4ZXVA 3FCJA 1FS9A 3GQTA 3MDEA 3TORA 5K3JA 2YYJA 2JBSA 3MKHA 2WBIA 1IVHA 2E81A 2RDZA 3NF4A 2DVLA 3D9GA 3BNFA 1SIRA 1JQIA 5K3IA 4OO2A 2ZO5A 2A1TA 2REHA 4Q5CA 3PFDA 4KCFA 3MXLA 1IS2A 3OWAA 2J7AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1UDY A;  3B96 A;  2D29 A;  3GNC A;  4O5M A;  2JBR A;  4Q17 A;  4Q1O A;  2ZAF A;  2RF7 A;  2JIF A;  4DOY A;  3D6B A;  5K3H A;  2VR0 A;  2OT4 A;  3X0Y A;  3P4T A;  1U8V A;  3D1I A;  4Q0T A;  3GM6 A;  3MPI A;  3SCE A;  4WJY A;  3LGQ A;  3F29 A;  2CX9 A;  4HR3 A;  2OR0 A;  1RX0 A;  2R0M A;  3D9D A;  1FS7 A;  1SIQ A;  3X0X A;  3BNJ A;  3MDD A;  4W9U A;  3LG1 A;  4IV6 A;  3OWM A;  4X28 A;  3S7W A;  1W07 A;  3RKH A;  4G5E A;  5K3G A;  1FS8 A;  2IX5 A;  2PG0 A;  2FON A;  3BNH A;  3OIB A;  2EBA A;  4L3X A;  4RM7 A;  4Q4U A;  2RFQ A;  2C0U A;  4L38 A;  2YYK A;  4U83 A;  3FO3 A;  3R7K A;  4P13 A;  1UKW A;  2UXW A;  2Z1Q A;  3MPJ A;  3TTB A;  4IRN A;  2YYM A;  3II9 A;  1WS9 A;  4X28 C;  4M9A A;  4KTO A;  1QDB A;  3HWC A;  3AFE A;  2YYL A;  4XVX A;  2C12 A;  3BNG A;  2VIG A;  4ZYJ A;  2IX6 A;  3L1T A;  3SWO A;  2JBT A;  2R0N A;  1R2J A;  4Q5B A;  1GU6 A;  4JEK A;  2YYG A;  1BUC A;  3UBR A;  1EGD A;  2YYI A;  4N5F A;  4NXL A;  3EOM A;  3SF6 A;  1EGE A;  3MMO A;  1OAH A;  3AFF A;  3M9V A;  4L3Z A;  3D9E A;  4L3Y A;  3EON A;  2DDH A;  2E80 A;  1EGC A;  3D9F A;  4L1F A;  3UU9 A;  3SXQ A;  1T9G A;  4ZXV A;  3FCJ A;  1FS9 A;  3GQT A;  3MDE A;  3TOR A;  5K3J A;  2YYJ A;  2JBS A;  3MKH A;  2WBI A;  1IVH A;  2E81 A;  2RDZ A;  3NF4 A;  2DVL A;  3D9G A;  3BNF A;  1SIR A;  1JQI A;  5K3I A;  4OO2 A;  2ZO5 A;  2A1T A;  2REH A;  4Q5C A;  3PFD A;  4KCF A;  3MXL A;  1IS2 A;  3OWA A;  2J7A A; 
#chains in the Genus database with same CATH topology
 1UDY A;  5B6B A;  1R3B A;  5B5V A;  3B96 A;  2D29 A;  3GNC A;  4O5M A;  2JBR A;  4Q17 A;  1RJ4 A;  4Q1O A;  2ZAF A;  2RF7 A;  2JIF A;  3TZ2 A;  4DOY A;  1XFU A;  1Y0V A;  2XS8 A;  3D6B A;  5K3H A;  1SK6 A;  2ZDY A;  2Q8H A;  2VR0 A;  2OT4 A;  3X0Y A;  4MPC A;  2Q8I A;  1X90 A;  3P4T A;  1U8V A;  3D1I A;  4Q0T A;  2Q8F A;  2PO4 A;  3VKG A;  3CRK A;  3GM6 A;  1RJ1 A;  3MPI A;  3SCE A;  4V25 A;  3TZ0 A;  1X8Z A;  2PNR A;  2ZDX A;  4WJY A;  3LGQ A;  2ZKJ A;  3F29 A;  2BU7 A;  4HKS A;  3D2R A;  2CX9 A;  4HR3 A;  2OR0 A;  1RX0 A;  2R0M A;  3D9D A;  1FS7 A;  1SIQ A;  3X0X A;  3BNJ A;  3MDD A;  4W9U A;  3X29 A;  3LG1 A;  4IV6 A;  1XFZ A;  3U33 A;  3OWM A;  4X28 A;  4LQS B;  3S7W A;  3Q0A A;  2R03 A;  1W07 A;  2YGW A;  4MPE A;  3RKH A;  4G5E A;  5K3G A;  1FS8 A;  4LQQ B;  1S26 A;  3Q23 A;  2IX5 A;  2CJ8 A;  4AI6 A;  2R05 A;  5J6A A;  3VKH A;  5EZ3 A;  2PG0 A;  2FON A;  1X91 A;  5GJV E;  3BNH A;  5BRK A;  1PK0 A;  4AKG A;  2BU2 A;  3OIB A;  2EBA A;  4L3X A;  4RM7 A;  4Q4U A;  2RFQ A;  5M4M A;  2C0U A;  4L38 A;  2R02 A;  2F6L A;  4U83 A;  2YYK A;  4FF3 A;  1LVC A;  3FO3 A;  2FP1 A;  2OJQ A;  3R7K A;  1SC5 A;  1XFW A;  2BU6 A;  4P13 A;  5M4N A;  4J1V A;  1UKW A;  2UXW A;  1XG2 B;  2Z1Q A;  3MPJ A;  3TTB A;  4IRN A;  2YYM A;  4KS9 A;  1JM6 A;  3II9 A;  1Y8P A;  3CE2 A;  4HKR A;  4KSF A;  1WS9 A;  4X28 C;  2AO2 A;  4M9A A;  4KTO A;  4JIZ A;  1K93 A;  3TZ5 A;  1QDB A;  3CRL A;  3VAD A;  2XS1 A;  1GKX A;  4FF2 A;  3HWC A;  3AFE A;  2YYL A;  2XQR B;  1GJV A;  4XVX A;  4MP2 A;  2CJ7 A;  3KML A;  4MPN A;  3C3L A;  1Y8N A;  2C12 A;  2CJ5 A;  2GBB A;  3BNG A;  2Q8G A;  2VIG A;  3Q24 A;  4ZYJ A;  3TZ4 A;  5B5W A;  3DJL A;  4AKI A;  2EBH X;  2IX6 A;  3L1T A;  4MP7 A;  3SWO A;  2JBT A;  2QR4 A;  2CJ6 A;  5M4K A;  4E02 A;  2R0N A;  1R2J A;  4Q5B A;  1GU6 A;  4DZY A;  4JEK A;  2YYG A;  1BUC A;  3UBR A;  1EGD A;  2EC5 A;  2HJN A;  4N5F A;  2YYI A;  2FP2 A;  4G97 A;  4NXL A;  3N0R A;  2AZE A;  3EOM A;  1XFY A;  4FZ4 A;  3SF6 A;  1EGE A;  3MMO A;  4P79 A;  2CJ4 A;  1OAH A;  2E0A A;  3AFF A;  3M9V A;  4H7Q A;  3Q22 A;  1XFV A;  4L3Z A;  5M4P A;  3D9E A;  4L3Y A;  4H85 A;  4E00 A;  3EON A;  2DDH A;  2E80 A;  2OEX A;  4KSA A;  1EGC A;  3D9F A;  4L1F A;  2BU5 A;  2OEV A;  3UU9 A;  3SXQ A;  1T9G A;  4ZXV A;  3FCJ A;  1FS9 A;  3GQT A;  1Y8O A;  2EBF X;  3MDE A;  2BTZ A;  4QIC A;  3TOR A;  5K3J A;  2YYJ A;  2JBS A;  4H81 A;  4V26 A;  5GJW E;  3MKH A;  4FF4 A;  2WBI A;  1K90 A;  1IVH A;  4F0X A;  2E81 A;  2RDZ A;  5BRM A;  1PI1 A;  3NF4 A;  2DVL A;  4FF1 A;  3D9G A;  3BNF A;  1SIR A;  1JQI A;  5J71 A;  5K3I A;  1K8T A;  2BU8 A;  2VF1 A;  2ZO5 A;  4OO2 A;  2A1T A;  2REH A;  1GKZ A;  4AKH A;  4Q5C A;  3PFD A;  1XFX A;  2LFW A;  4KCF A;  3MXL A;  1IS2 A;  4JIO A;  4E01 A;  3C2P A;  3C46 A;  1RP3 A;  3OWA A;  2J7A A; 
#chains in the Genus database with same CATH homology
 1UDY A;  3B96 A;  2D29 A;  3GNC A;  4O5M A;  2JBR A;  4Q17 A;  4Q1O A;  2ZAF A;  2RF7 A;  2JIF A;  4DOY A;  3D6B A;  5K3H A;  2VR0 A;  2OT4 A;  3X0Y A;  3P4T A;  1U8V A;  3D1I A;  4Q0T A;  3GM6 A;  3MPI A;  3SCE A;  4WJY A;  3LGQ A;  3F29 A;  2CX9 A;  4HR3 A;  2OR0 A;  1RX0 A;  2R0M A;  3D9D A;  1FS7 A;  1SIQ A;  3X0X A;  3BNJ A;  3MDD A;  4W9U A;  3LG1 A;  4IV6 A;  3OWM A;  4X28 A;  3S7W A;  1W07 A;  3RKH A;  4G5E A;  5K3G A;  1FS8 A;  2IX5 A;  2PG0 A;  2FON A;  3BNH A;  3OIB A;  2EBA A;  4L3X A;  4RM7 A;  4Q4U A;  2RFQ A;  2C0U A;  4L38 A;  2YYK A;  4U83 A;  3FO3 A;  3R7K A;  4P13 A;  1UKW A;  2UXW A;  2Z1Q A;  3MPJ A;  3TTB A;  4IRN A;  2YYM A;  3II9 A;  1WS9 A;  4X28 C;  4M9A A;  4KTO A;  1QDB A;  3HWC A;  3AFE A;  2YYL A;  4XVX A;  2C12 A;  3BNG A;  2VIG A;  4ZYJ A;  2IX6 A;  3L1T A;  3SWO A;  2JBT A;  2R0N A;  1R2J A;  4Q5B A;  1GU6 A;  4JEK A;  2YYG A;  1BUC A;  3UBR A;  1EGD A;  2YYI A;  4N5F A;  4NXL A;  3EOM A;  3SF6 A;  1EGE A;  3MMO A;  1OAH A;  3AFF A;  3M9V A;  4L3Z A;  3D9E A;  4L3Y A;  3EON A;  2DDH A;  2E80 A;  1EGC A;  3D9F A;  4L1F A;  3UU9 A;  3SXQ A;  1T9G A;  4ZXV A;  3FCJ A;  1FS9 A;  3GQT A;  3MDE A;  3TOR A;  5K3J A;  2YYJ A;  2JBS A;  3MKH A;  2WBI A;  1IVH A;  2E81 A;  2RDZ A;  3NF4 A;  2DVL A;  3D9G A;  3BNF A;  1SIR A;  1JQI A;  5K3I A;  4OO2 A;  2ZO5 A;  2A1T A;  2REH A;  4Q5C A;  3PFD A;  4KCF A;  3MXL A;  1IS2 A;  3OWA A;  2J7A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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