3GQTA

Crystal structure of glutaryl-coa dehydrogenase from burkholderia pseudomallei with fragment (1,4-dimethyl-1,2,3,4-tetrahydroquinoxalin-6-yl)methylamine
Total Genus 154
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
154
sequence length
391
structure length
383
Chain Sequence
ATFHWDDPLLLDQQLADDERMVRDAAHAYAQGKLAPRVTEAFRHETTDAAIFREMGEIGLLGPTIPEQYGGPGLDYVSYGLIAREVERVDSGYRSMMSVQSSLVMVPIFEFGSDAQKEKYLPKLATGEWIGCFGLTEPPGSMVTRARKVPGGYSLSGSKMWITNSPIADVFVVWAKLDEDGRDEIRGFILEKGCKGLSAPAIHGKVGLRASITGEIVLDEAFVPEENILPHVKGLRGPFTCLNSARYGIAWGALGAAESCWHIARQYVLDRKQFGRPLAANQLIQKKLADMQTEITLGLQGVLRLGRMKDEGTAAVEITSIMKRNSCGKALDIARLARDMLGGNGISDEFGVARHLVNLEVVNTYHDIHALILGRAQTGIQAF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
molecule keywords Glutaryl-CoA dehydrogenase
publication title Probing conformational states of glutaryl-CoA dehydrogenase by fragment screening.
pubmed doi rcsb
source organism Burkholderia pseudomallei
total genus 154
structure length 383
sequence length 391
chains with identical sequence B, C, D
ec nomenclature ec 1.3.99.7: Transferred entry: 1.3.8.6.
pdb deposition date 2009-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 3gqtA01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 3gqtA03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 3gqtA02
3AFFA 2RF7A 4Q0TA 3X0YA 3R7KA 3SWOA 3D9DA 2VR0A 1EGEA 3UU9A 1EGCA 3GQTA 1GU6A 3OIBA 4DOYA 3AFEA 1SIRA 3EONA 3P4TA 3NF4A 4OO2A 3EOMA 3BNHA 1WS9A 3RKHA 3MPJA 3UBRA 1QDBA 1FS7A 1U8VA 2R0MA 2C0UA 3OWMA 3X0XA 2YYJA 1OAHA 3SF6A 3F29A 4ZYJA 5K3HA 2JIFA 3HWCA 2RDZA 4IRNA 3MPIA 3OWAA 3S7WA 4L3ZA 4HR3A 3LG1A 1T9GA 2E80A 2JBTA 4O5MA 4KTOA 2VIGA 4M9AA 2REHA 5K3IA 4L1FA 3D9FA 2OT4A 3BNJA 4Q1OA 3MXLA 2WBIA 2PG0A 3GM6A 2A1TA 4L3YA 4X28C 1UKWA 4WJYA 3MDDA 4NXLA 2FONA 3II9A 1EGDA 4L3XA 2DDHA 4Q17A 2R0NA 1BUCA 3SCEA 2ZO5A 3LGQA 2OR0A 3SXQA 3D1IA 2C12A 3D9GA 4U83A 2YYLA 3M9VA 1JQIA 2YYKA 3TTBA 1SIQA 5K3JA 1IVHA 4P13A 3D9EA 3L1TA 4Q5BA 1UDYA 3MMOA 1W07A 4RM7A 1FS9A 3TORA 2IX6A 2JBSA 2J7AA 3MDEA 4N5FA 1IS2A 3FCJA 4G5EA 3BNGA 4KCFA 2UXWA 2RFQA 2Z1QA 4IV6A 2CX9A 2IX5A 2E81A 1FS8A 2JBRA 4JEKA 3MKHA 2YYIA 4X28A 4Q4UA 4Q5CA 2ZAFA 3FO3A 3PFDA 2YYMA 2YYGA 3B96A 3GNCA 3D6BA 4XVXA 5K3GA 3BNFA 2D29A 4L38A 2DVLA 4W9UA 2EBAA 4ZXVA 1RX0A 1R2JA
chains in the Genus database with same CATH superfamily
2Q8GA 3AFFA 2RF7A 4Q0TA 4FF3A 4J1VA 5M4KA 4HKSA 4FF4A 3X0YA 3R7KA 3SWOA 2CJ4A 3D9DA 2CJ7A 4L38A 3Q0AA 2VR0A 1EGEA 2HJNA 1XFZA 5GJWE 3UU9A 1EGCA 3GQTA 1GU6A 3OIBA 4DOYA 3AFEA 1SIRA 1R3BA 1XFVA 2BU7A 2FP1A 3EONA 3P4TA 4AKHA 4E02A 3NF4A 2BU6A 4H7QA 3VKHA 4OO2A 2QR4A 2OEVA 3EOMA 3BNHA 5J6AA 2Q8FA 5B5WA 5EZ3A 5BRMA 1WS9A 2EBHX 3C3LA 1K93A 3KMLA 4V26A 1SC5A 3RKHA 4MPCA 3MPJA 1S26A 2LFWA 3UBRA 5BRKA 1QDBA 2R02A 1FS7A 1RP3A 1U8VA 2R0MA 1XFXA 2OEXA 3CRKA 3VKGA 3U33A 2C0UA 3OWMA 2FP2A 3X0XA 1XFYA 2YYJA 2ZDYA 1OAHA 4KSFA 3SF6A 3F29A 4ZYJA 5K3HA 1Y0VA 2JIFA 3HWCA 1K8TA 2R05A 5M4PA 5M4MA 2RDZA 4IRNA 3MPIA 3VADA 3OWAA 3TZ4A 3S7WA 4L3ZA 4HR3A 2Q8IA 3LG1A 1T9GA 3Q23A 2E80A 2JBTA 1GJVA 4HKRA 3C46A 2R03A 2ZDXA 2AO2A 2PO4A 4MP7A 2Q8HA 1LVCA 2GBBA 4O5MA 4KTOA 1GKXA 2VIGA 4M9AA 4G97A 3TZ5A 4AKGA 4AI6A 2REHA 3TZ0A 1X8ZA 5K3IA 4L1FA 3D9FA 1XFUA 2PNRA 2OT4A 5GJVE 3BNJA 1RJ4A 2OJQA 3Q24A 4Q1OA 3MXLA 2CJ5A 2WBIA 2PG0A 4JIOA 3GM6A 2XS8A 1K90A 2A1TA 3X29A 4L3YA 4X28C 2BU5A 1UKWA 4WJYA 4MP2A 3MDDA 4NXLA 3CE2A 2FONA 1Y8OA 1Y8NA 3II9A 1EGDA 5B5VA 4AKIA 3DJLA 4L3XA 2DDHA 3Q22A 4LQSB 2R0NA 4Q17A 1BUCA 2CJ6A 4FF2A 3SCEA 2BU8A 2ZO5A 4JIZA 3LGQA 2OR0A 4FF1A 3SXQA 3D1IA 2C12A 3C2PA 3D9GA 2XS1A 3N0RA 4U83A 2F6LA 2YYLA 3M9VA 1JQIA 2YYKA 4LQQB 3TTBA 1PK0A 5M4NA 2YGWA 1SIQA 5K3JA 4V25A 1IVHA 4P13A 3D9EA 3L1TA 1RJ1A 5B6BA 4MPNA 4Q5BA 4FZ4A 1UDYA 4F0XA 3MMOA 1W07A 2BTZA 2EC5A 4RM7A 4E00A 1FS9A 3TORA 1Y8PA 2CJ8A 2IX6A 4MPEA 2JBSA 3CRLA 2J7AA 3MDEA 3D2RA 4KSAA 4N5FA 1IS2A 3FCJA 4G5EA 3BNGA 2E0AA 2AZEA 4KCFA 3TZ2A 2UXWA 2RFQA 2Z1QA 4IV6A 4QICA 1X91A 2CX9A 2IX5A 5J71A 2E81A 1FS8A 2BU2A 2JBRA 4JEKA 3MKHA 1GKZA 1SK6A 4X28A 2EBFX 2YYIA 4Q4UA 4Q5CA 2ZAFA 2XQRB 3PFDA 1X90A 2YYMA 3FO3A 2YYGA 3B96A 3GNCA 3D6BA 4XVXA 5K3GA 1JM6A 2D29A 1XG2B 1XFWA 3BNFA 2DVLA 4W9UA 2ZKJA 4P79A 2VF1A 4DZYA 2EBAA 4ZXVA 1PI1A 4H81A 4KS9A 1RX0A 4E01A 1R2JA 4H85A
chains in the Genus database with same CATH topology
3AFFA 2RF7A 4Q0TA 3X0YA 3R7KA 3SWOA 3D9DA 2VR0A 1EGEA 3UU9A 1EGCA 3GQTA 1GU6A 3OIBA 4DOYA 3AFEA 1SIRA 3EONA 3P4TA 3NF4A 4OO2A 3EOMA 3BNHA 1WS9A 3RKHA 3MPJA 3UBRA 1QDBA 1FS7A 1U8VA 2R0MA 2C0UA 3OWMA 3X0XA 2YYJA 1OAHA 3SF6A 3F29A 4ZYJA 5K3HA 2JIFA 3HWCA 2RDZA 4IRNA 3MPIA 3OWAA 3S7WA 4L3ZA 4HR3A 3LG1A 1T9GA 2E80A 2JBTA 4O5MA 4KTOA 2VIGA 4M9AA 2REHA 5K3IA 4L1FA 3D9FA 2OT4A 3BNJA 4Q1OA 3MXLA 2WBIA 2PG0A 3GM6A 2A1TA 4L3YA 4X28C 1UKWA 4WJYA 3MDDA 4NXLA 2FONA 3II9A 1EGDA 4L3XA 2DDHA 4Q17A 2R0NA 1BUCA 3SCEA 2ZO5A 3LGQA 2OR0A 3SXQA 3D1IA 2C12A 3D9GA 4U83A 2YYLA 3M9VA 1JQIA 2YYKA 3TTBA 1SIQA 5K3JA 1IVHA 4P13A 3D9EA 3L1TA 4Q5BA 1UDYA 3MMOA 1W07A 4RM7A 1FS9A 3TORA 2IX6A 2JBSA 2J7AA 3MDEA 4N5FA 1IS2A 3FCJA 4G5EA 3BNGA 4KCFA 2UXWA 2RFQA 2Z1QA 4IV6A 2CX9A 2IX5A 2E81A 1FS8A 2JBRA 4JEKA 3MKHA 2YYIA 4X28A 4Q4UA 4Q5CA 2ZAFA 3FO3A 3PFDA 2YYMA 2YYGA 3B96A 3GNCA 3D6BA 4XVXA 5K3GA 3BNFA 2D29A 4L38A 2DVLA 4W9UA 2EBAA 4ZXVA 1RX0A 1R2JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AFF A;  2RF7 A;  4Q0T A;  3X0Y A;  3R7K A;  3SWO A;  3D9D A;  2VR0 A;  1EGE A;  3UU9 A;  1EGC A;  3GQT A;  1GU6 A;  3OIB A;  4DOY A;  3AFE A;  1SIR A;  3EON A;  3P4T A;  3NF4 A;  4OO2 A;  3EOM A;  3BNH A;  1WS9 A;  3RKH A;  3MPJ A;  3UBR A;  1QDB A;  1FS7 A;  1U8V A;  2R0M A;  2C0U A;  3OWM A;  3X0X A;  2YYJ A;  1OAH A;  3SF6 A;  3F29 A;  4ZYJ A;  5K3H A;  2JIF A;  3HWC A;  2RDZ A;  4IRN A;  3MPI A;  3OWA A;  3S7W A;  4L3Z A;  4HR3 A;  3LG1 A;  1T9G A;  2E80 A;  2JBT A;  4O5M A;  4KTO A;  2VIG A;  4M9A A;  2REH A;  5K3I A;  4L1F A;  3D9F A;  2OT4 A;  3BNJ A;  4Q1O A;  3MXL A;  2WBI A;  2PG0 A;  3GM6 A;  2A1T A;  4L3Y A;  4X28 C;  1UKW A;  4WJY A;  3MDD A;  4NXL A;  2FON A;  3II9 A;  1EGD A;  4L3X A;  2DDH A;  4Q17 A;  2R0N A;  1BUC A;  3SCE A;  2ZO5 A;  3LGQ A;  2OR0 A;  3SXQ A;  3D1I A;  2C12 A;  3D9G A;  4U83 A;  2YYL A;  3M9V A;  1JQI A;  2YYK A;  3TTB A;  1SIQ A;  5K3J A;  1IVH A;  4P13 A;  3D9E A;  3L1T A;  4Q5B A;  1UDY A;  3MMO A;  1W07 A;  4RM7 A;  1FS9 A;  3TOR A;  2IX6 A;  2JBS A;  2J7A A;  3MDE A;  4N5F A;  1IS2 A;  3FCJ A;  4G5E A;  3BNG A;  4KCF A;  2UXW A;  2RFQ A;  2Z1Q A;  4IV6 A;  2CX9 A;  2IX5 A;  2E81 A;  1FS8 A;  2JBR A;  4JEK A;  3MKH A;  2YYI A;  4X28 A;  4Q4U A;  4Q5C A;  2ZAF A;  3FO3 A;  3PFD A;  2YYM A;  2YYG A;  3B96 A;  3GNC A;  3D6B A;  4XVX A;  5K3G A;  3BNF A;  2D29 A;  4L38 A;  2DVL A;  4W9U A;  2EBA A;  4ZXV A;  1RX0 A;  1R2J A; 
#chains in the Genus database with same CATH topology
 2Q8G A;  3AFF A;  2RF7 A;  4Q0T A;  4FF3 A;  4J1V A;  5M4K A;  4HKS A;  4FF4 A;  3X0Y A;  3R7K A;  3SWO A;  2CJ4 A;  3D9D A;  2CJ7 A;  4L38 A;  3Q0A A;  2VR0 A;  1EGE A;  2HJN A;  1XFZ A;  5GJW E;  3UU9 A;  1EGC A;  3GQT A;  1GU6 A;  3OIB A;  4DOY A;  3AFE A;  1SIR A;  1R3B A;  1XFV A;  2BU7 A;  2FP1 A;  3EON A;  3P4T A;  4AKH A;  4E02 A;  3NF4 A;  2BU6 A;  4H7Q A;  3VKH A;  4OO2 A;  2QR4 A;  2OEV A;  3EOM A;  3BNH A;  5J6A A;  2Q8F A;  5B5W A;  5EZ3 A;  5BRM A;  1WS9 A;  2EBH X;  3C3L A;  1K93 A;  3KML A;  4V26 A;  1SC5 A;  3RKH A;  4MPC A;  3MPJ A;  1S26 A;  2LFW A;  3UBR A;  5BRK A;  1QDB A;  2R02 A;  1FS7 A;  1RP3 A;  1U8V A;  2R0M A;  1XFX A;  2OEX A;  3CRK A;  3VKG A;  3U33 A;  2C0U A;  3OWM A;  2FP2 A;  3X0X A;  1XFY A;  2YYJ A;  2ZDY A;  1OAH A;  4KSF A;  3SF6 A;  3F29 A;  4ZYJ A;  5K3H A;  1Y0V A;  2JIF A;  3HWC A;  1K8T A;  2R05 A;  5M4P A;  5M4M A;  2RDZ A;  4IRN A;  3MPI A;  3VAD A;  3OWA A;  3TZ4 A;  3S7W A;  4L3Z A;  4HR3 A;  2Q8I A;  3LG1 A;  1T9G A;  3Q23 A;  2E80 A;  2JBT A;  1GJV A;  4HKR A;  3C46 A;  2R03 A;  2ZDX A;  2AO2 A;  2PO4 A;  4MP7 A;  2Q8H A;  1LVC A;  2GBB A;  4O5M A;  4KTO A;  1GKX A;  2VIG A;  4M9A A;  4G97 A;  3TZ5 A;  4AKG A;  4AI6 A;  2REH A;  3TZ0 A;  1X8Z A;  5K3I A;  4L1F A;  3D9F A;  1XFU A;  2PNR A;  2OT4 A;  5GJV E;  3BNJ A;  1RJ4 A;  2OJQ A;  3Q24 A;  4Q1O A;  3MXL A;  2CJ5 A;  2WBI A;  2PG0 A;  4JIO A;  3GM6 A;  2XS8 A;  1K90 A;  2A1T A;  3X29 A;  4L3Y A;  4X28 C;  2BU5 A;  1UKW A;  4WJY A;  4MP2 A;  3MDD A;  4NXL A;  3CE2 A;  2FON A;  1Y8O A;  1Y8N A;  3II9 A;  1EGD A;  5B5V A;  4AKI A;  3DJL A;  4L3X A;  2DDH A;  3Q22 A;  4LQS B;  2R0N A;  4Q17 A;  1BUC A;  2CJ6 A;  4FF2 A;  3SCE A;  2BU8 A;  2ZO5 A;  4JIZ A;  3LGQ A;  2OR0 A;  4FF1 A;  3SXQ A;  3D1I A;  2C12 A;  3C2P A;  3D9G A;  2XS1 A;  3N0R A;  4U83 A;  2F6L A;  2YYL A;  3M9V A;  1JQI A;  2YYK A;  4LQQ B;  3TTB A;  1PK0 A;  5M4N A;  2YGW A;  1SIQ A;  5K3J A;  4V25 A;  1IVH A;  4P13 A;  3D9E A;  3L1T A;  1RJ1 A;  5B6B A;  4MPN A;  4Q5B A;  4FZ4 A;  1UDY A;  4F0X A;  3MMO A;  1W07 A;  2BTZ A;  2EC5 A;  4RM7 A;  4E00 A;  1FS9 A;  3TOR A;  1Y8P A;  2CJ8 A;  2IX6 A;  4MPE A;  2JBS A;  3CRL A;  2J7A A;  3MDE A;  3D2R A;  4KSA A;  4N5F A;  1IS2 A;  3FCJ A;  4G5E A;  3BNG A;  2E0A A;  2AZE A;  4KCF A;  3TZ2 A;  2UXW A;  2RFQ A;  2Z1Q A;  4IV6 A;  4QIC A;  1X91 A;  2CX9 A;  2IX5 A;  5J71 A;  2E81 A;  1FS8 A;  2BU2 A;  2JBR A;  4JEK A;  3MKH A;  1GKZ A;  1SK6 A;  4X28 A;  2EBF X;  2YYI A;  4Q4U A;  4Q5C A;  2ZAF A;  2XQR B;  3PFD A;  1X90 A;  2YYM A;  3FO3 A;  2YYG A;  3B96 A;  3GNC A;  3D6B A;  4XVX A;  5K3G A;  1JM6 A;  2D29 A;  1XG2 B;  1XFW A;  3BNF A;  2DVL A;  4W9U A;  2ZKJ A;  4P79 A;  2VF1 A;  4DZY A;  2EBA A;  4ZXV A;  1PI1 A;  4H81 A;  4KS9 A;  1RX0 A;  4E01 A;  1R2J A;  4H85 A; 
#chains in the Genus database with same CATH homology
 3AFF A;  2RF7 A;  4Q0T A;  3X0Y A;  3R7K A;  3SWO A;  3D9D A;  2VR0 A;  1EGE A;  3UU9 A;  1EGC A;  3GQT A;  1GU6 A;  3OIB A;  4DOY A;  3AFE A;  1SIR A;  3EON A;  3P4T A;  3NF4 A;  4OO2 A;  3EOM A;  3BNH A;  1WS9 A;  3RKH A;  3MPJ A;  3UBR A;  1QDB A;  1FS7 A;  1U8V A;  2R0M A;  2C0U A;  3OWM A;  3X0X A;  2YYJ A;  1OAH A;  3SF6 A;  3F29 A;  4ZYJ A;  5K3H A;  2JIF A;  3HWC A;  2RDZ A;  4IRN A;  3MPI A;  3OWA A;  3S7W A;  4L3Z A;  4HR3 A;  3LG1 A;  1T9G A;  2E80 A;  2JBT A;  4O5M A;  4KTO A;  2VIG A;  4M9A A;  2REH A;  5K3I A;  4L1F A;  3D9F A;  2OT4 A;  3BNJ A;  4Q1O A;  3MXL A;  2WBI A;  2PG0 A;  3GM6 A;  2A1T A;  4L3Y A;  4X28 C;  1UKW A;  4WJY A;  3MDD A;  4NXL A;  2FON A;  3II9 A;  1EGD A;  4L3X A;  2DDH A;  4Q17 A;  2R0N A;  1BUC A;  3SCE A;  2ZO5 A;  3LGQ A;  2OR0 A;  3SXQ A;  3D1I A;  2C12 A;  3D9G A;  4U83 A;  2YYL A;  3M9V A;  1JQI A;  2YYK A;  3TTB A;  1SIQ A;  5K3J A;  1IVH A;  4P13 A;  3D9E A;  3L1T A;  4Q5B A;  1UDY A;  3MMO A;  1W07 A;  4RM7 A;  1FS9 A;  3TOR A;  2IX6 A;  2JBS A;  2J7A A;  3MDE A;  4N5F A;  1IS2 A;  3FCJ A;  4G5E A;  3BNG A;  4KCF A;  2UXW A;  2RFQ A;  2Z1Q A;  4IV6 A;  2CX9 A;  2IX5 A;  2E81 A;  1FS8 A;  2JBR A;  4JEK A;  3MKH A;  2YYI A;  4X28 A;  4Q4U A;  4Q5C A;  2ZAF A;  3FO3 A;  3PFD A;  2YYM A;  2YYG A;  3B96 A;  3GNC A;  3D6B A;  4XVX A;  5K3G A;  3BNF A;  2D29 A;  4L38 A;  2DVL A;  4W9U A;  2EBA A;  4ZXV A;  1RX0 A;  1R2J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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