4P13A

Medium chain acyl-coa dehydrogenase, k304e mutant
Total Genus 146
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
146
sequence length
387
structure length
387
Chain Sequence
LGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMEVELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDKYKN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Oxidoreductase
molecule keywords Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
publication title Medium chain acyl-CoA dehydrogenase, K304E mutant
rcsb
source organism Homo sapiens
total genus 146
structure length 387
sequence length 387
chains with identical sequence B, C, D
ec nomenclature ec 1.3.8.7: Medium-chain acyl-CoA dehydrogenase.
pdb deposition date 2014-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 4p13A01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 4p13A03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 4p13A02
2ZAFA 4Q4UA 3MPJA 3UU9A 4IRNA 3D9EA 2OT4A 3II9A 4ZXVA 1T9GA 4M9AA 2YYJA 3M9VA 2Z1QA 3MKHA 1EGEA 4L3XA 4KCFA 4XVXA 4IV6A 3D9FA 1QDBA 4Q17A 3SCEA 3RKHA 3OWAA 3NF4A 2E80A 3MMOA 1WS9A 1OAHA 1SIRA 3BNHA 2FONA 3MDDA 3TORA 3D6BA 3D1IA 4U83A 2DDHA 4Q0TA 3D9DA 1R2JA 3UBRA 3BNGA 1FS8A 3X0XA 3D9GA 2UXWA 2VIGA 3P4TA 2DVLA 3B96A 3MDEA 1U8VA 3FO3A 4L3YA 3R7KA 2C12A 5K3IA 2YYLA 2RFQA 2YYGA 2R0MA 4P13A 1RX0A 4Q5CA 1IVHA 3PFDA 4X28C 4L1FA 2JBRA 1SIQA 2PG0A 3BNJA 2YYIA 4JEKA 2REHA 2IX6A 2EBAA 3TTBA 4W9UA 3GQTA 4WJYA 2D29A 3F29A 4L3ZA 2E81A 3LG1A 2JBTA 4G5EA 2C0UA 5K3JA 4Q1OA 3S7WA 2WBIA 2RDZA 3L1TA 2IX5A 3HWCA 2YYMA 1GU6A 3LGQA 1BUCA 3FCJA 4RM7A 1FS7A 4ZYJA 4O5MA 5K3GA 2J7AA 1EGDA 4L38A 3EOMA 2A1TA 1FS9A 3MXLA 1JQIA 4OO2A 4X28A 4NXLA 2JIFA 3AFFA 1UKWA 4Q5BA 2OR0A 3OWMA 3AFEA 1UDYA 4DOYA 4HR3A 3EONA 3MPIA 3GM6A 2YYKA 2ZO5A 2JBSA 1W07A 2CX9A 3GNCA 3OIBA 4N5FA 3X0YA 3SXQA 1EGCA 1IS2A 3SWOA 2VR0A 2R0NA 3SF6A 3BNFA 5K3HA 4KTOA 2RF7A
chains in the Genus database with same CATH superfamily
2ZAFA 2BU5A 2E0AA 3X29A 2CJ6A 4Q4UA 3MPJA 1Y8NA 3UU9A 2EBHX 4IRNA 3D9EA 2PNRA 2OT4A 3II9A 4ZXVA 4H7QA 1X8ZA 1T9GA 4M9AA 4HKRA 4F0XA 2Q8HA 2YYJA 4H85A 2OJQA 2YGWA 3M9VA 5BRKA 2Z1QA 5M4NA 3MKHA 2CJ5A 3TZ2A 1EGEA 4L3XA 4KCFA 5B6BA 4XVXA 4IV6A 2BTZA 1Y0VA 3D9FA 1QDBA 4Q17A 4HKSA 3RKHA 3SCEA 3OWAA 2Q8GA 2BU2A 3NF4A 2E80A 3TZ0A 3MMOA 1WS9A 1OAHA 3Q23A 1SIRA 3BNHA 4FZ4A 4E01A 4FF1A 2FONA 3MDDA 4AKGA 2XS8A 3TORA 3C3LA 3D6BA 4MPNA 3VADA 3D1IA 4U83A 1XG2B 1PK0A 3CE2A 1SC5A 5J6AA 2DDHA 4Q0TA 4J1VA 3D9DA 1R2JA 3UBRA 3TZ5A 3BNGA 1FS8A 1XFYA 3X0XA 2R05A 3D9GA 4G97A 4KS9A 2UXWA 2VIGA 3P4TA 2AZEA 2DVLA 4AKIA 4FF3A 3B96A 3MDEA 1U8VA 3FO3A 4L3YA 4QICA 3R7KA 4H81A 4V25A 2CJ8A 2C12A 5K3IA 2YYLA 2RFQA 2R03A 2BU8A 1K8TA 2YYGA 2R0MA 4P13A 1RX0A 4LQSB 4Q5CA 1LVCA 1IVHA 3C46A 3PFDA 4X28C 2AO2A 4L1FA 2JBRA 4MP2A 3U33A 2OEVA 1K90A 1SIQA 2PG0A 5B5WA 1JM6A 3BNJA 3D2RA 2YYIA 2R02A 4JEKA 2QR4A 2FP1A 2CJ7A 2REHA 2IX6A 5BRMA 3TZ4A 2EBAA 3TTBA 1XFUA 3Q0AA 5B5VA 4W9UA 2VF1A 4LQQB 3GQTA 4AKHA 4WJYA 2D29A 3F29A 4L3ZA 3VKHA 2E81A 2EC5A 5GJVE 3LG1A 2JBTA 1RJ1A 2C0UA 5K3JA 4G5EA 4E00A 2LFWA 2PO4A 4AI6A 2BU7A 5EZ3A 1X90A 1X91A 2FP2A 4Q1OA 3S7WA 4DZYA 2XQRB 2WBIA 2RDZA 3L1TA 2IX5A 3N0RA 5M4MA 3HWCA 3KMLA 2YYMA 1XFXA 1GU6A 1RJ4A 2Q8FA 3LGQA 4MP7A 1BUCA 2CJ4A 3FCJA 4RM7A 1FS7A 4ZYJA 1S26A 2HJNA 4JIOA 4MPCA 4P79A 4O5MA 3Q22A 5K3GA 2J7AA 1XFWA 2BU6A 5M4KA 1EGDA 2ZDXA 4L38A 3EOMA 2GBBA 2A1TA 1FS9A 2ZDYA 5M4PA 1R3BA 2XS1A 3MXLA 1GJVA 1JQIA 1GKXA 1XFZA 3C2PA 2Q8IA 1SK6A 1Y8PA 2ZKJA 4X28A 4OO2A 4FF2A 4NXLA 3VKGA 2JIFA 3AFFA 1UKWA 4Q5BA 4JIZA 4E02A 1GKZA 2OR0A 3OWMA 1PI1A 3AFEA 3CRKA 4FF4A 2F6LA 2EBFX 3DJLA 1UDYA 4DOYA 4HR3A 3EONA 3MPIA 4KSFA 3GM6A 2YYKA 2ZO5A 4V26A 2JBSA 1W07A 2CX9A 3GNCA 3OIBA 4N5FA 3X0YA 3CRLA 1EGCA 5GJWE 3SXQA 1IS2A 3SWOA 2VR0A 2OEXA 1Y8OA 2R0NA 4KSAA 1RP3A 3SF6A 3BNFA 4MPEA 5J71A 5K3HA 3Q24A 4KTOA 2RF7A 1K93A 1XFVA
chains in the Genus database with same CATH topology
2ZAFA 4Q4UA 3MPJA 3UU9A 4IRNA 3D9EA 2OT4A 3II9A 4ZXVA 1T9GA 4M9AA 2YYJA 3M9VA 2Z1QA 3MKHA 1EGEA 4L3XA 4KCFA 4XVXA 4IV6A 3D9FA 1QDBA 4Q17A 3SCEA 3RKHA 3OWAA 3NF4A 2E80A 3MMOA 1WS9A 1OAHA 1SIRA 3BNHA 2FONA 3MDDA 3TORA 3D6BA 3D1IA 4U83A 2DDHA 4Q0TA 3D9DA 1R2JA 3UBRA 3BNGA 1FS8A 3X0XA 3D9GA 2UXWA 2VIGA 3P4TA 2DVLA 3B96A 3MDEA 1U8VA 3FO3A 4L3YA 3R7KA 2C12A 5K3IA 2YYLA 2RFQA 2YYGA 2R0MA 4P13A 1RX0A 4Q5CA 1IVHA 3PFDA 4X28C 4L1FA 2JBRA 1SIQA 2PG0A 3BNJA 2YYIA 4JEKA 2REHA 2IX6A 2EBAA 3TTBA 4W9UA 3GQTA 4WJYA 2D29A 3F29A 4L3ZA 2E81A 3LG1A 2JBTA 4G5EA 2C0UA 5K3JA 4Q1OA 3S7WA 2WBIA 2RDZA 3L1TA 2IX5A 3HWCA 2YYMA 1GU6A 3LGQA 1BUCA 3FCJA 4RM7A 1FS7A 4ZYJA 4O5MA 5K3GA 2J7AA 1EGDA 4L38A 3EOMA 2A1TA 1FS9A 3MXLA 1JQIA 4OO2A 4X28A 4NXLA 2JIFA 3AFFA 1UKWA 4Q5BA 2OR0A 3OWMA 3AFEA 1UDYA 4DOYA 4HR3A 3EONA 3MPIA 3GM6A 2YYKA 2ZO5A 2JBSA 1W07A 2CX9A 3GNCA 3OIBA 4N5FA 3X0YA 3SXQA 1EGCA 1IS2A 3SWOA 2VR0A 2R0NA 3SF6A 3BNFA 5K3HA 4KTOA 2RF7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZAF A;  4Q4U A;  3MPJ A;  3UU9 A;  4IRN A;  3D9E A;  2OT4 A;  3II9 A;  4ZXV A;  1T9G A;  4M9A A;  2YYJ A;  3M9V A;  2Z1Q A;  3MKH A;  1EGE A;  4L3X A;  4KCF A;  4XVX A;  4IV6 A;  3D9F A;  1QDB A;  4Q17 A;  3SCE A;  3RKH A;  3OWA A;  3NF4 A;  2E80 A;  3MMO A;  1WS9 A;  1OAH A;  1SIR A;  3BNH A;  2FON A;  3MDD A;  3TOR A;  3D6B A;  3D1I A;  4U83 A;  2DDH A;  4Q0T A;  3D9D A;  1R2J A;  3UBR A;  3BNG A;  1FS8 A;  3X0X A;  3D9G A;  2UXW A;  2VIG A;  3P4T A;  2DVL A;  3B96 A;  3MDE A;  1U8V A;  3FO3 A;  4L3Y A;  3R7K A;  2C12 A;  5K3I A;  2YYL A;  2RFQ A;  2YYG A;  2R0M A;  4P13 A;  1RX0 A;  4Q5C A;  1IVH A;  3PFD A;  4X28 C;  4L1F A;  2JBR A;  1SIQ A;  2PG0 A;  3BNJ A;  2YYI A;  4JEK A;  2REH A;  2IX6 A;  2EBA A;  3TTB A;  4W9U A;  3GQT A;  4WJY A;  2D29 A;  3F29 A;  4L3Z A;  2E81 A;  3LG1 A;  2JBT A;  4G5E A;  2C0U A;  5K3J A;  4Q1O A;  3S7W A;  2WBI A;  2RDZ A;  3L1T A;  2IX5 A;  3HWC A;  2YYM A;  1GU6 A;  3LGQ A;  1BUC A;  3FCJ A;  4RM7 A;  1FS7 A;  4ZYJ A;  4O5M A;  5K3G A;  2J7A A;  1EGD A;  4L38 A;  3EOM A;  2A1T A;  1FS9 A;  3MXL A;  1JQI A;  4OO2 A;  4X28 A;  4NXL A;  2JIF A;  3AFF A;  1UKW A;  4Q5B A;  2OR0 A;  3OWM A;  3AFE A;  1UDY A;  4DOY A;  4HR3 A;  3EON A;  3MPI A;  3GM6 A;  2YYK A;  2ZO5 A;  2JBS A;  1W07 A;  2CX9 A;  3GNC A;  3OIB A;  4N5F A;  3X0Y A;  3SXQ A;  1EGC A;  1IS2 A;  3SWO A;  2VR0 A;  2R0N A;  3SF6 A;  3BNF A;  5K3H A;  4KTO A;  2RF7 A; 
#chains in the Genus database with same CATH topology
 2ZAF A;  2BU5 A;  2E0A A;  3X29 A;  2CJ6 A;  4Q4U A;  3MPJ A;  1Y8N A;  3UU9 A;  2EBH X;  4IRN A;  3D9E A;  2PNR A;  2OT4 A;  3II9 A;  4ZXV A;  4H7Q A;  1X8Z A;  1T9G A;  4M9A A;  4HKR A;  4F0X A;  2Q8H A;  2YYJ A;  4H85 A;  2OJQ A;  2YGW A;  3M9V A;  5BRK A;  2Z1Q A;  5M4N A;  3MKH A;  2CJ5 A;  3TZ2 A;  1EGE A;  4L3X A;  4KCF A;  5B6B A;  4XVX A;  4IV6 A;  2BTZ A;  1Y0V A;  3D9F A;  1QDB A;  4Q17 A;  4HKS A;  3RKH A;  3SCE A;  3OWA A;  2Q8G A;  2BU2 A;  3NF4 A;  2E80 A;  3TZ0 A;  3MMO A;  1WS9 A;  1OAH A;  3Q23 A;  1SIR A;  3BNH A;  4FZ4 A;  4E01 A;  4FF1 A;  2FON A;  3MDD A;  4AKG A;  2XS8 A;  3TOR A;  3C3L A;  3D6B A;  4MPN A;  3VAD A;  3D1I A;  4U83 A;  1XG2 B;  1PK0 A;  3CE2 A;  1SC5 A;  5J6A A;  2DDH A;  4Q0T A;  4J1V A;  3D9D A;  1R2J A;  3UBR A;  3TZ5 A;  3BNG A;  1FS8 A;  1XFY A;  3X0X A;  2R05 A;  3D9G A;  4G97 A;  4KS9 A;  2UXW A;  2VIG A;  3P4T A;  2AZE A;  2DVL A;  4AKI A;  4FF3 A;  3B96 A;  3MDE A;  1U8V A;  3FO3 A;  4L3Y A;  4QIC A;  3R7K A;  4H81 A;  4V25 A;  2CJ8 A;  2C12 A;  5K3I A;  2YYL A;  2RFQ A;  2R03 A;  2BU8 A;  1K8T A;  2YYG A;  2R0M A;  4P13 A;  1RX0 A;  4LQS B;  4Q5C A;  1LVC A;  1IVH A;  3C46 A;  3PFD A;  4X28 C;  2AO2 A;  4L1F A;  2JBR A;  4MP2 A;  3U33 A;  2OEV A;  1K90 A;  1SIQ A;  2PG0 A;  5B5W A;  1JM6 A;  3BNJ A;  3D2R A;  2YYI A;  2R02 A;  4JEK A;  2QR4 A;  2FP1 A;  2CJ7 A;  2REH A;  2IX6 A;  5BRM A;  3TZ4 A;  2EBA A;  3TTB A;  1XFU A;  3Q0A A;  5B5V A;  4W9U A;  2VF1 A;  4LQQ B;  3GQT A;  4AKH A;  4WJY A;  2D29 A;  3F29 A;  4L3Z A;  3VKH A;  2E81 A;  2EC5 A;  5GJV E;  3LG1 A;  2JBT A;  1RJ1 A;  2C0U A;  5K3J A;  4G5E A;  4E00 A;  2LFW A;  2PO4 A;  4AI6 A;  2BU7 A;  5EZ3 A;  1X90 A;  1X91 A;  2FP2 A;  4Q1O A;  3S7W A;  4DZY A;  2XQR B;  2WBI A;  2RDZ A;  3L1T A;  2IX5 A;  3N0R A;  5M4M A;  3HWC A;  3KML A;  2YYM A;  1XFX A;  1GU6 A;  1RJ4 A;  2Q8F A;  3LGQ A;  4MP7 A;  1BUC A;  2CJ4 A;  3FCJ A;  4RM7 A;  1FS7 A;  4ZYJ A;  1S26 A;  2HJN A;  4JIO A;  4MPC A;  4P79 A;  4O5M A;  3Q22 A;  5K3G A;  2J7A A;  1XFW A;  2BU6 A;  5M4K A;  1EGD A;  2ZDX A;  4L38 A;  3EOM A;  2GBB A;  2A1T A;  1FS9 A;  2ZDY A;  5M4P A;  1R3B A;  2XS1 A;  3MXL A;  1GJV A;  1JQI A;  1GKX A;  1XFZ A;  3C2P A;  2Q8I A;  1SK6 A;  1Y8P A;  2ZKJ A;  4X28 A;  4OO2 A;  4FF2 A;  4NXL A;  3VKG A;  2JIF A;  3AFF A;  1UKW A;  4Q5B A;  4JIZ A;  4E02 A;  1GKZ A;  2OR0 A;  3OWM A;  1PI1 A;  3AFE A;  3CRK A;  4FF4 A;  2F6L A;  2EBF X;  3DJL A;  1UDY A;  4DOY A;  4HR3 A;  3EON A;  3MPI A;  4KSF A;  3GM6 A;  2YYK A;  2ZO5 A;  4V26 A;  2JBS A;  1W07 A;  2CX9 A;  3GNC A;  3OIB A;  4N5F A;  3X0Y A;  3CRL A;  1EGC A;  5GJW E;  3SXQ A;  1IS2 A;  3SWO A;  2VR0 A;  2OEX A;  1Y8O A;  2R0N A;  4KSA A;  1RP3 A;  3SF6 A;  3BNF A;  4MPE A;  5J71 A;  5K3H A;  3Q24 A;  4KTO A;  2RF7 A;  1K93 A;  1XFV A; 
#chains in the Genus database with same CATH homology
 2ZAF A;  4Q4U A;  3MPJ A;  3UU9 A;  4IRN A;  3D9E A;  2OT4 A;  3II9 A;  4ZXV A;  1T9G A;  4M9A A;  2YYJ A;  3M9V A;  2Z1Q A;  3MKH A;  1EGE A;  4L3X A;  4KCF A;  4XVX A;  4IV6 A;  3D9F A;  1QDB A;  4Q17 A;  3SCE A;  3RKH A;  3OWA A;  3NF4 A;  2E80 A;  3MMO A;  1WS9 A;  1OAH A;  1SIR A;  3BNH A;  2FON A;  3MDD A;  3TOR A;  3D6B A;  3D1I A;  4U83 A;  2DDH A;  4Q0T A;  3D9D A;  1R2J A;  3UBR A;  3BNG A;  1FS8 A;  3X0X A;  3D9G A;  2UXW A;  2VIG A;  3P4T A;  2DVL A;  3B96 A;  3MDE A;  1U8V A;  3FO3 A;  4L3Y A;  3R7K A;  2C12 A;  5K3I A;  2YYL A;  2RFQ A;  2YYG A;  2R0M A;  4P13 A;  1RX0 A;  4Q5C A;  1IVH A;  3PFD A;  4X28 C;  4L1F A;  2JBR A;  1SIQ A;  2PG0 A;  3BNJ A;  2YYI A;  4JEK A;  2REH A;  2IX6 A;  2EBA A;  3TTB A;  4W9U A;  3GQT A;  4WJY A;  2D29 A;  3F29 A;  4L3Z A;  2E81 A;  3LG1 A;  2JBT A;  4G5E A;  2C0U A;  5K3J A;  4Q1O A;  3S7W A;  2WBI A;  2RDZ A;  3L1T A;  2IX5 A;  3HWC A;  2YYM A;  1GU6 A;  3LGQ A;  1BUC A;  3FCJ A;  4RM7 A;  1FS7 A;  4ZYJ A;  4O5M A;  5K3G A;  2J7A A;  1EGD A;  4L38 A;  3EOM A;  2A1T A;  1FS9 A;  3MXL A;  1JQI A;  4OO2 A;  4X28 A;  4NXL A;  2JIF A;  3AFF A;  1UKW A;  4Q5B A;  2OR0 A;  3OWM A;  3AFE A;  1UDY A;  4DOY A;  4HR3 A;  3EON A;  3MPI A;  3GM6 A;  2YYK A;  2ZO5 A;  2JBS A;  1W07 A;  2CX9 A;  3GNC A;  3OIB A;  4N5F A;  3X0Y A;  3SXQ A;  1EGC A;  1IS2 A;  3SWO A;  2VR0 A;  2R0N A;  3SF6 A;  3BNF A;  5K3H A;  4KTO A;  2RF7 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...