1UDYA

Medium-chain acyl-coa dehydrogenase with 3-thiaoctanoyl-coa
Total Genus 139
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
385
structure length
385
Chain Sequence
GFSFELTEQQKEFQATARKFAREEIIPVAAEYDRTGEYPVPLLKRAWELGLMNTHIPESFGGLGLGIIDSCLITEELAYGCTGVQTAIEANTLGQVPLIIGGNYQQQKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPASKAFTGFIVEADTPGVQIGRKEINMGQRCSDTRGIVFEDVRVPKENVLTGEGAGFKIAMGTFDKTRPPVAAGAVGLAQRALDEATKYALERKTFGKLLAEHQGISFLLADMAMKVELARLSYQRAAWEIDSGRRNTYYASIAKAYAADIANQLATDAVQVFGGNGFNTEYPVEKLMRDAKIYQIYEGTAQIQRIIIAREHIGRYK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
molecule keywords Acyl-CoA dehydrogenase, medium-chain specific
publication title Structure of the transition state analog of medium-chain acyl-CoA dehydrogenase. Crystallographic and molecular orbital studies on the charge-transfer complex of medium-chain acyl-CoA dehydrogenase with 3-thiaoctanoyl-CoA
pubmed doi rcsb
total genus 139
structure length 385
sequence length 385
chains with identical sequence B, C, D
ec nomenclature ec 1.3.8.7: Medium-chain acyl-CoA dehydrogenase.
pdb deposition date 2003-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 1udyA01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 1udyA03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 1udyA02
2PG0A 2YYGA 1QDBA 3MDEA 2FONA 3MMOA 1R2JA 2EBAA 1SIRA 2IX5A 2A1TA 2ZO5A 2DVLA 2YYIA 2OR0A 3MDDA 3M9VA 4RM7A 3BNGA 4Q1OA 4X28A 1FS8A 2R0NA 2YYMA 3FO3A 2VR0A 4HR3A 3SXQA 1UKWA 4KTOA 4L1FA 5K3JA 2JIFA 3UBRA 1BUCA 2WBIA 2RFQA 1IVHA 3LGQA 4IV6A 4L3ZA 3MKHA 3D6BA 3TTBA 1UDYA 5K3GA 4Q0TA 1WS9A 2YYJA 3GM6A 1RX0A 4W9UA 2E80A 3NF4A 3P4TA 3OWMA 2REHA 3MPIA 3R7KA 5K3IA 2DDHA 4XVXA 1FS7A 4JEKA 3MPJA 4Q5BA 1JQIA 4IRNA 2R0MA 4L3YA 3TORA 3SF6A 4P13A 3X0YA 3B96A 4Q17A 4Q5CA 2IX6A 3D9GA 3D9FA 3GQTA 2RDZA 3S7WA 2YYKA 3BNFA 3F29A 4WJYA 4ZYJA 1SIQA 3EONA 3FCJA 4N5FA 4L3XA 3OWAA 3MXLA 3X0XA 2C0UA 4M9AA 3AFEA 4X28C 4L38A 3BNHA 2D29A 3SCEA 3SWOA 4NXLA 2CX9A 2JBTA 2UXWA 4Q4UA 3RKHA 3HWCA 3EOMA 4G5EA 2E81A 3OIBA 2VIGA 2ZAFA 1T9GA 2J7AA 4ZXVA 4OO2A 3PFDA 4U83A 4O5MA 1GU6A 2Z1QA 3LG1A 1OAHA 3BNJA 1W07A 3D9EA 2JBSA 3D9DA 3D1IA 3GNCA 2RF7A 4DOYA 3AFFA 1EGCA 1FS9A 1EGDA 5K3HA 3UU9A 1IS2A 2YYLA 4KCFA 3II9A 2OT4A 2JBRA 2C12A 3L1TA 1U8VA 1EGEA
chains in the Genus database with same CATH superfamily
2PG0A 2YYGA 2BTZA 3CRLA 3CE2A 2XS8A 1QDBA 5GJWE 3MDEA 1K90A 3DJLA 2FONA 2CJ7A 3MMOA 3VKGA 3U33A 1R2JA 2EBAA 1SIRA 2IX5A 3X29A 2A1TA 1Y0VA 4H7QA 2ZO5A 2GBBA 2DVLA 2R05A 1XG2B 2YYIA 2FP2A 2Q8HA 5J6AA 2OR0A 3MDDA 2CJ8A 3M9VA 4RM7A 2FP1A 3BNGA 4Q1OA 4X28A 1FS8A 2R03A 4KS9A 2BU5A 2XS1A 2R0NA 2YYMA 1K93A 3FO3A 1RJ4A 1PI1A 4DZYA 4AI6A 2LFWA 4MPCA 4FF3A 2AO2A 5M4PA 2VR0A 4HR3A 4H85A 3SXQA 1UKWA 5B5WA 4KTOA 4L1FA 5K3JA 2ZKJA 2JIFA 5GJVE 3UBRA 1BUCA 3TZ5A 2WBIA 4FZ4A 3VADA 2RFQA 1RP3A 1Y8NA 1IVHA 1X91A 2EBFX 3LGQA 3N0RA 4HKSA 4IV6A 4L3ZA 3TZ0A 4V25A 3MKHA 4LQQB 4H81A 4LQSB 4FF1A 1GKZA 3D6BA 4G97A 1SK6A 3TTBA 4E02A 1UDYA 4JIOA 3Q23A 5K3GA 2BU8A 4Q0TA 1WS9A 2YYJA 3GM6A 1JM6A 1X90A 1RX0A 4W9UA 2Q8FA 5M4KA 3Q22A 1Y8PA 2E80A 2VF1A 3C2PA 3NF4A 3P4TA 3KMLA 3OWMA 2REHA 1R3BA 2OEVA 3MPIA 3R7KA 4FF4A 5K3IA 2DDHA 4XVXA 1FS7A 2F6LA 4JEKA 3MPJA 4Q5BA 1JQIA 4IRNA 4AKHA 4AKGA 2R0MA 4J1VA 1GKXA 1X8ZA 3CRKA 4L3YA 3TORA 3SF6A 4KSAA 2CJ5A 4P13A 2CJ4A 5J71A 2AZEA 3X0YA 1GJVA 3B96A 4KSFA 4Q17A 4Q5CA 2IX6A 3D9GA 3D9FA 3GQTA 2PNRA 2RDZA 3S7WA 2YYKA 2PO4A 3BNFA 3F29A 2CJ6A 4WJYA 3Q24A 4ZYJA 1SIQA 3EONA 3FCJA 4N5FA 1XFYA 2ZDYA 4MPEA 4L3XA 3OWAA 3MXLA 3X0XA 2QR4A 2C0UA 4M9AA 1S26A 3AFEA 4MPNA 4X28C 2BU7A 3BNHA 2D29A 4L38A 5BRMA 3SWOA 3SCEA 4NXLA 2CX9A 1K8TA 3C46A 4JIZA 2YGWA 2JBTA 1Y8OA 2UXWA 4Q4UA 2EBHX 3RKHA 3Q0AA 3HWCA 2HJNA 3EOMA 4G5EA 4MP7A 2BU6A 1PK0A 3OIBA 2VIGA 2ZAFA 2E81A 1T9GA 2J7AA 4ZXVA 2BU2A 4OO2A 3TZ4A 5B6BA 3PFDA 4U83A 4O5MA 1GU6A 1SC5A 2Z1QA 3LG1A 4F0XA 1LVCA 1OAHA 4V26A 3BNJA 2Q8GA 5M4NA 1W07A 2OEXA 4MP2A 3D9EA 3TZ2A 5BRKA 2ZDXA 2OJQA 2JBSA 3D9DA 4QICA 3D1IA 2E0AA 4E00A 4P79A 5B5VA 4E01A 3GNCA 2RF7A 4DOYA 3AFFA 1EGCA 1FS9A 3VKHA 1XFVA 1EGDA 5K3HA 1XFXA 3UU9A 4HKRA 2Q8IA 5EZ3A 1XFZA 1IS2A 4FF2A 4AKIA 2YYLA 4KCFA 3D2RA 3II9A 1XFUA 1XFWA 1RJ1A 3C3LA 2EC5A 2OT4A 2JBRA 2XQRB 2C12A 3L1TA 2R02A 5M4MA 1U8VA 1EGEA
chains in the Genus database with same CATH topology
2PG0A 2YYGA 1QDBA 3MDEA 2FONA 3MMOA 1R2JA 2EBAA 1SIRA 2IX5A 2A1TA 2ZO5A 2DVLA 2YYIA 2OR0A 3MDDA 3M9VA 4RM7A 3BNGA 4Q1OA 4X28A 1FS8A 2R0NA 2YYMA 3FO3A 2VR0A 4HR3A 3SXQA 1UKWA 4KTOA 4L1FA 5K3JA 2JIFA 3UBRA 1BUCA 2WBIA 2RFQA 1IVHA 3LGQA 4IV6A 4L3ZA 3MKHA 3D6BA 3TTBA 1UDYA 5K3GA 4Q0TA 1WS9A 2YYJA 3GM6A 1RX0A 4W9UA 2E80A 3NF4A 3P4TA 3OWMA 2REHA 3MPIA 3R7KA 5K3IA 2DDHA 4XVXA 1FS7A 4JEKA 3MPJA 4Q5BA 1JQIA 4IRNA 2R0MA 4L3YA 3TORA 3SF6A 4P13A 3X0YA 3B96A 4Q17A 4Q5CA 2IX6A 3D9GA 3D9FA 3GQTA 2RDZA 3S7WA 2YYKA 3BNFA 3F29A 4WJYA 4ZYJA 1SIQA 3EONA 3FCJA 4N5FA 4L3XA 3OWAA 3MXLA 3X0XA 2C0UA 4M9AA 3AFEA 4X28C 4L38A 3BNHA 2D29A 3SCEA 3SWOA 4NXLA 2CX9A 2JBTA 2UXWA 4Q4UA 3RKHA 3HWCA 3EOMA 4G5EA 2E81A 3OIBA 2VIGA 2ZAFA 1T9GA 2J7AA 4ZXVA 4OO2A 3PFDA 4U83A 4O5MA 1GU6A 2Z1QA 3LG1A 1OAHA 3BNJA 1W07A 3D9EA 2JBSA 3D9DA 3D1IA 3GNCA 2RF7A 4DOYA 3AFFA 1EGCA 1FS9A 1EGDA 5K3HA 3UU9A 1IS2A 2YYLA 4KCFA 3II9A 2OT4A 2JBRA 2C12A 3L1TA 1U8VA 1EGEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PG0 A;  2YYG A;  1QDB A;  3MDE A;  2FON A;  3MMO A;  1R2J A;  2EBA A;  1SIR A;  2IX5 A;  2A1T A;  2ZO5 A;  2DVL A;  2YYI A;  2OR0 A;  3MDD A;  3M9V A;  4RM7 A;  3BNG A;  4Q1O A;  4X28 A;  1FS8 A;  2R0N A;  2YYM A;  3FO3 A;  2VR0 A;  4HR3 A;  3SXQ A;  1UKW A;  4KTO A;  4L1F A;  5K3J A;  2JIF A;  3UBR A;  1BUC A;  2WBI A;  2RFQ A;  1IVH A;  3LGQ A;  4IV6 A;  4L3Z A;  3MKH A;  3D6B A;  3TTB A;  1UDY A;  5K3G A;  4Q0T A;  1WS9 A;  2YYJ A;  3GM6 A;  1RX0 A;  4W9U A;  2E80 A;  3NF4 A;  3P4T A;  3OWM A;  2REH A;  3MPI A;  3R7K A;  5K3I A;  2DDH A;  4XVX A;  1FS7 A;  4JEK A;  3MPJ A;  4Q5B A;  1JQI A;  4IRN A;  2R0M A;  4L3Y A;  3TOR A;  3SF6 A;  4P13 A;  3X0Y A;  3B96 A;  4Q17 A;  4Q5C A;  2IX6 A;  3D9G A;  3D9F A;  3GQT A;  2RDZ A;  3S7W A;  2YYK A;  3BNF A;  3F29 A;  4WJY A;  4ZYJ A;  1SIQ A;  3EON A;  3FCJ A;  4N5F A;  4L3X A;  3OWA A;  3MXL A;  3X0X A;  2C0U A;  4M9A A;  3AFE A;  4X28 C;  4L38 A;  3BNH A;  2D29 A;  3SCE A;  3SWO A;  4NXL A;  2CX9 A;  2JBT A;  2UXW A;  4Q4U A;  3RKH A;  3HWC A;  3EOM A;  4G5E A;  2E81 A;  3OIB A;  2VIG A;  2ZAF A;  1T9G A;  2J7A A;  4ZXV A;  4OO2 A;  3PFD A;  4U83 A;  4O5M A;  1GU6 A;  2Z1Q A;  3LG1 A;  1OAH A;  3BNJ A;  1W07 A;  3D9E A;  2JBS A;  3D9D A;  3D1I A;  3GNC A;  2RF7 A;  4DOY A;  3AFF A;  1EGC A;  1FS9 A;  1EGD A;  5K3H A;  3UU9 A;  1IS2 A;  2YYL A;  4KCF A;  3II9 A;  2OT4 A;  2JBR A;  2C12 A;  3L1T A;  1U8V A;  1EGE A; 
#chains in the Genus database with same CATH topology
 2PG0 A;  2YYG A;  2BTZ A;  3CRL A;  3CE2 A;  2XS8 A;  1QDB A;  5GJW E;  3MDE A;  1K90 A;  3DJL A;  2FON A;  2CJ7 A;  3MMO A;  3VKG A;  3U33 A;  1R2J A;  2EBA A;  1SIR A;  2IX5 A;  3X29 A;  2A1T A;  1Y0V A;  4H7Q A;  2ZO5 A;  2GBB A;  2DVL A;  2R05 A;  1XG2 B;  2YYI A;  2FP2 A;  2Q8H A;  5J6A A;  2OR0 A;  3MDD A;  2CJ8 A;  3M9V A;  4RM7 A;  2FP1 A;  3BNG A;  4Q1O A;  4X28 A;  1FS8 A;  2R03 A;  4KS9 A;  2BU5 A;  2XS1 A;  2R0N A;  2YYM A;  1K93 A;  3FO3 A;  1RJ4 A;  1PI1 A;  4DZY A;  4AI6 A;  2LFW A;  4MPC A;  4FF3 A;  2AO2 A;  5M4P A;  2VR0 A;  4HR3 A;  4H85 A;  3SXQ A;  1UKW A;  5B5W A;  4KTO A;  4L1F A;  5K3J A;  2ZKJ A;  2JIF A;  5GJV E;  3UBR A;  1BUC A;  3TZ5 A;  2WBI A;  4FZ4 A;  3VAD A;  2RFQ A;  1RP3 A;  1Y8N A;  1IVH A;  1X91 A;  2EBF X;  3LGQ A;  3N0R A;  4HKS A;  4IV6 A;  4L3Z A;  3TZ0 A;  4V25 A;  3MKH A;  4LQQ B;  4H81 A;  4LQS B;  4FF1 A;  1GKZ A;  3D6B A;  4G97 A;  1SK6 A;  3TTB A;  4E02 A;  1UDY A;  4JIO A;  3Q23 A;  5K3G A;  2BU8 A;  4Q0T A;  1WS9 A;  2YYJ A;  3GM6 A;  1JM6 A;  1X90 A;  1RX0 A;  4W9U A;  2Q8F A;  5M4K A;  3Q22 A;  1Y8P A;  2E80 A;  2VF1 A;  3C2P A;  3NF4 A;  3P4T A;  3KML A;  3OWM A;  2REH A;  1R3B A;  2OEV A;  3MPI A;  3R7K A;  4FF4 A;  5K3I A;  2DDH A;  4XVX A;  1FS7 A;  2F6L A;  4JEK A;  3MPJ A;  4Q5B A;  1JQI A;  4IRN A;  4AKH A;  4AKG A;  2R0M A;  4J1V A;  1GKX A;  1X8Z A;  3CRK A;  4L3Y A;  3TOR A;  3SF6 A;  4KSA A;  2CJ5 A;  4P13 A;  2CJ4 A;  5J71 A;  2AZE A;  3X0Y A;  1GJV A;  3B96 A;  4KSF A;  4Q17 A;  4Q5C A;  2IX6 A;  3D9G A;  3D9F A;  3GQT A;  2PNR A;  2RDZ A;  3S7W A;  2YYK A;  2PO4 A;  3BNF A;  3F29 A;  2CJ6 A;  4WJY A;  3Q24 A;  4ZYJ A;  1SIQ A;  3EON A;  3FCJ A;  4N5F A;  1XFY A;  2ZDY A;  4MPE A;  4L3X A;  3OWA A;  3MXL A;  3X0X A;  2QR4 A;  2C0U A;  4M9A A;  1S26 A;  3AFE A;  4MPN A;  4X28 C;  2BU7 A;  3BNH A;  2D29 A;  4L38 A;  5BRM A;  3SWO A;  3SCE A;  4NXL A;  2CX9 A;  1K8T A;  3C46 A;  4JIZ A;  2YGW A;  2JBT A;  1Y8O A;  2UXW A;  4Q4U A;  2EBH X;  3RKH A;  3Q0A A;  3HWC A;  2HJN A;  3EOM A;  4G5E A;  4MP7 A;  2BU6 A;  1PK0 A;  3OIB A;  2VIG A;  2ZAF A;  2E81 A;  1T9G A;  2J7A A;  4ZXV A;  2BU2 A;  4OO2 A;  3TZ4 A;  5B6B A;  3PFD A;  4U83 A;  4O5M A;  1GU6 A;  1SC5 A;  2Z1Q A;  3LG1 A;  4F0X A;  1LVC A;  1OAH A;  4V26 A;  3BNJ A;  2Q8G A;  5M4N A;  1W07 A;  2OEX A;  4MP2 A;  3D9E A;  3TZ2 A;  5BRK A;  2ZDX A;  2OJQ A;  2JBS A;  3D9D A;  4QIC A;  3D1I A;  2E0A A;  4E00 A;  4P79 A;  5B5V A;  4E01 A;  3GNC A;  2RF7 A;  4DOY A;  3AFF A;  1EGC A;  1FS9 A;  3VKH A;  1XFV A;  1EGD A;  5K3H A;  1XFX A;  3UU9 A;  4HKR A;  2Q8I A;  5EZ3 A;  1XFZ A;  1IS2 A;  4FF2 A;  4AKI A;  2YYL A;  4KCF A;  3D2R A;  3II9 A;  1XFU A;  1XFW A;  1RJ1 A;  3C3L A;  2EC5 A;  2OT4 A;  2JBR A;  2XQR B;  2C12 A;  3L1T A;  2R02 A;  5M4M A;  1U8V A;  1EGE A; 
#chains in the Genus database with same CATH homology
 2PG0 A;  2YYG A;  1QDB A;  3MDE A;  2FON A;  3MMO A;  1R2J A;  2EBA A;  1SIR A;  2IX5 A;  2A1T A;  2ZO5 A;  2DVL A;  2YYI A;  2OR0 A;  3MDD A;  3M9V A;  4RM7 A;  3BNG A;  4Q1O A;  4X28 A;  1FS8 A;  2R0N A;  2YYM A;  3FO3 A;  2VR0 A;  4HR3 A;  3SXQ A;  1UKW A;  4KTO A;  4L1F A;  5K3J A;  2JIF A;  3UBR A;  1BUC A;  2WBI A;  2RFQ A;  1IVH A;  3LGQ A;  4IV6 A;  4L3Z A;  3MKH A;  3D6B A;  3TTB A;  1UDY A;  5K3G A;  4Q0T A;  1WS9 A;  2YYJ A;  3GM6 A;  1RX0 A;  4W9U A;  2E80 A;  3NF4 A;  3P4T A;  3OWM A;  2REH A;  3MPI A;  3R7K A;  5K3I A;  2DDH A;  4XVX A;  1FS7 A;  4JEK A;  3MPJ A;  4Q5B A;  1JQI A;  4IRN A;  2R0M A;  4L3Y A;  3TOR A;  3SF6 A;  4P13 A;  3X0Y A;  3B96 A;  4Q17 A;  4Q5C A;  2IX6 A;  3D9G A;  3D9F A;  3GQT A;  2RDZ A;  3S7W A;  2YYK A;  3BNF A;  3F29 A;  4WJY A;  4ZYJ A;  1SIQ A;  3EON A;  3FCJ A;  4N5F A;  4L3X A;  3OWA A;  3MXL A;  3X0X A;  2C0U A;  4M9A A;  3AFE A;  4X28 C;  4L38 A;  3BNH A;  2D29 A;  3SCE A;  3SWO A;  4NXL A;  2CX9 A;  2JBT A;  2UXW A;  4Q4U A;  3RKH A;  3HWC A;  3EOM A;  4G5E A;  2E81 A;  3OIB A;  2VIG A;  2ZAF A;  1T9G A;  2J7A A;  4ZXV A;  4OO2 A;  3PFD A;  4U83 A;  4O5M A;  1GU6 A;  2Z1Q A;  3LG1 A;  1OAH A;  3BNJ A;  1W07 A;  3D9E A;  2JBS A;  3D9D A;  3D1I A;  3GNC A;  2RF7 A;  4DOY A;  3AFF A;  1EGC A;  1FS9 A;  1EGD A;  5K3H A;  3UU9 A;  1IS2 A;  2YYL A;  4KCF A;  3II9 A;  2OT4 A;  2JBR A;  2C12 A;  3L1T A;  1U8V A;  1EGE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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