2AZEA

Structure of the rb c-terminal domain bound to an e2f1-dp1 heterodimer
Total Genus 41
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
149
structure length
149
Chain Sequence
FAQECQNLEVERQRRLERIKQKQSQLQELILQQIAFKNLVQRNRHAEQQASRPPPPNSVIHLPFIIVNTSKKTVIDCSISNDKFEYLFNFDNTFEIHDDIEVLKRMGMACGLESGSCSAEDLKMARSLVPKALEPYVTEMAQGTVGGVF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Cell cycle, transcription
molecule keywords Transcription factor Dp-1
publication title Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release.
pubmed doi rcsb
source organism Homo sapiens
total genus 41
structure length 149
sequence length 149
ec nomenclature
pdb deposition date 2005-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08781 DP Transcription factor DP
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.140.80 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A; domain 3 2azeA01
2AZEA
chains in the Genus database with same CATH superfamily
2OJQA 3TZ5A 1XFZA 2LFWA 3MKHA 5B5WA 1EGCA 4H81A 2FONA 3B96A 3SF6A 3C46A 3VKHA 4N5FA 2C0UA 2D29A 1EGDA 2Z1QA 3X0YA 2ZKJA 1Y8NA 4L3YA 2YYLA 3MDDA 4JIZA 1FS7A 1PK0A 1XG2B 3CRKA 2IX5A 1OAHA 2RFQA 3TZ0A 3X29A 3X0XA 4U83A 3VKGA 1WS9A 2JIFA 4G97A 4JEKA 5K3HA 1XFXA 4MP7A 4KSAA 4FF2A 2ZDXA 2ZDYA 2EBHX 1SC5A 2GBBA 3BNGA 2J7AA 2EC5A 2XS1A 1IS2A 3GNCA 4KS9A 4RM7A 2Q8FA 4DOYA 1X91A 2CJ8A 1UKWA 4MPEA 1XFVA 1SIQA 1GU6A 2VF1A 4P79A 5K3IA 1XFYA 3D9FA 2PG0A 3D9DA 1RX0A 1RJ4A 2BU5A 1X90A 2Q8HA 2R02A 4V26A 5M4NA 5M4KA 3TZ2A 2REHA 3D6BA 4IRNA 5K3GA 2R0MA 4WJYA 3C2PA 2Q8GA 2YYGA 1SIRA 4H85A 4P13A 3Q24A 1Y0VA 3GM6A 2JBTA 2XS8A 4Q5BA 4F0XA 4L3XA 1GKXA 4NXLA 4MPNA 3UU9A 1GJVA 2E80A 4OO2A 2JBSA 3LG1A 2PNRA 2BTZA 3FO3A 2IX6A 3F29A 4ZYJA 2YGWA 1XFUA 4KCFA 4KTOA 5BRKA 4DZYA 3C3LA 1R3BA 4V25A 5M4MA 2F6LA 4JIOA 2E81A 2OEXA 3EOMA 4HKSA 2C12A 4FF4A 2E0AA 2AO2A 1U8VA 2JBRA 2QR4A 1IVHA 4L3ZA 1SK6A 2R0NA 1RP3A 3NF4A 4X28C 2VR0A 1RJ1A 3BNHA 2RDZA 2BU2A 3BNFA 3L1TA 4L1FA 5BRMA 3Q23A 4AKGA 2YYMA 2VIGA 2FP2A 1R2JA 2ZAFA 3M9VA 4FZ4A 4HR3A 4L38A 2YYKA 3D9EA 4J1VA 5K3JA 3SXQA 1FS8A 1QDBA 1XFWA 2YYJA 4LQSB 4AKHA 1JM6A 1FS9A 5J6AA 3MPIA 1K90A 4IV6A 4X28A 2CJ7A 1Y8OA 2A1TA 2UXWA 3MXLA 3VADA 5B6BA 1S26A 2R05A 3KMLA 4XVXA 2RF7A 3MMOA 2DVLA 3FCJA 4LQQB 4E00A 2BU6A 2EBAA 4W9UA 3SCEA 3Q22A 2OEVA 3OWAA 3N0RA 5GJWE 2Q8IA 4O5MA 5M4PA 2OT4A 1GKZA 2BU8A 4H7QA 4Q17A 3AFFA 4MP2A 4QICA 4E01A 2WBIA 3SWOA 4FF1A 3BNJA 2DDHA 4Q5CA 3R7KA 1X8ZA 2CJ5A 3AFEA 1T9GA 3D2RA 4Q1OA 4G5EA 3HWCA 3OIBA 3Q0AA 1EGEA 3OWMA 4KSFA 2FP1A 4AI6A 4HKRA 2YYIA 2CJ4A 3GQTA 1JQIA 4MPCA 1LVCA 4M9AA 3PFDA 1UDYA 1K93A 3CRLA 5GJVE 2EBFX 2OR0A 3MPJA 3S7WA 3TORA 2HJNA 3TTBA 4FF3A 1PI1A 2PO4A 2AZEA 3RKHA 3TZ4A 4E02A 3II9A 1BUCA 4Q4UA 1Y8PA 2CX9A 4AKIA 2BU7A 3P4TA 4ZXVA 2R03A 1W07A 3MDEA 3D1IA 2CJ6A 5J71A 3CE2A 2ZO5A 3D9GA 3EONA 3LGQA 4Q0TA 3UBRA 1K8TA 2XQRB 5B5VA
chains in the Genus database with same CATH topology
3Q23A 4KSFA 1XFZA 2FP1A 2LFWA 4AI6A 4HKRA 4AKGA 2FP2A 4FZ4A 3C2PA 3VKHA 3C46A 1LVCA 3Q24A 4AKHA 1XFWA 1Y0VA 1K93A 5GJVE 4F0XA 2EBFX 1K90A 4FF4A 1PK0A 2PO4A 4FF3A 2AZEA 3X29A 1S26A 3KMLA 3C3LA 3VKGA 2YGWA 1XFUA 4G97A 3Q22A 2VF1A 1XFXA 4AKIA 2F6LA 4KSAA 3N0RA 5GJWE 4FF2A 2EBHX 1SC5A 2GBBA 4HKSA 4QICA 2EC5A 4KS9A 2AO2A 3CE2A 2QR4A 4FF1A 1SK6A 1RP3A 1XFVA 1K8TA 4P79A 1XFYA 3Q0AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AZE A; 
#chains in the Genus database with same CATH topology
 2OJQ A;  3TZ5 A;  1XFZ A;  2LFW A;  3MKH A;  5B5W A;  1EGC A;  4H81 A;  2FON A;  3B96 A;  3SF6 A;  3C46 A;  3VKH A;  4N5F A;  2C0U A;  2D29 A;  1EGD A;  2Z1Q A;  3X0Y A;  2ZKJ A;  1Y8N A;  4L3Y A;  2YYL A;  3MDD A;  4JIZ A;  1FS7 A;  1PK0 A;  1XG2 B;  3CRK A;  2IX5 A;  1OAH A;  2RFQ A;  3TZ0 A;  3X29 A;  3X0X A;  4U83 A;  3VKG A;  1WS9 A;  2JIF A;  4G97 A;  4JEK A;  5K3H A;  1XFX A;  4MP7 A;  4KSA A;  4FF2 A;  2ZDX A;  2ZDY A;  2EBH X;  1SC5 A;  2GBB A;  3BNG A;  2J7A A;  2EC5 A;  2XS1 A;  1IS2 A;  3GNC A;  4KS9 A;  4RM7 A;  2Q8F A;  4DOY A;  1X91 A;  2CJ8 A;  1UKW A;  4MPE A;  1XFV A;  1SIQ A;  1GU6 A;  2VF1 A;  4P79 A;  5K3I A;  1XFY A;  3D9F A;  2PG0 A;  3D9D A;  1RX0 A;  1RJ4 A;  2BU5 A;  1X90 A;  2Q8H A;  2R02 A;  4V26 A;  5M4N A;  5M4K A;  3TZ2 A;  2REH A;  3D6B A;  4IRN A;  5K3G A;  2R0M A;  4WJY A;  3C2P A;  2Q8G A;  2YYG A;  1SIR A;  4H85 A;  4P13 A;  3Q24 A;  1Y0V A;  3GM6 A;  2JBT A;  2XS8 A;  4Q5B A;  4F0X A;  4L3X A;  1GKX A;  4NXL A;  4MPN A;  3UU9 A;  1GJV A;  2E80 A;  4OO2 A;  2JBS A;  3LG1 A;  2PNR A;  2BTZ A;  3FO3 A;  2IX6 A;  3F29 A;  4ZYJ A;  2YGW A;  1XFU A;  4KCF A;  4KTO A;  5BRK A;  4DZY A;  3C3L A;  1R3B A;  4V25 A;  5M4M A;  2F6L A;  4JIO A;  2E81 A;  2OEX A;  3EOM A;  4HKS A;  2C12 A;  4FF4 A;  2E0A A;  2AO2 A;  1U8V A;  2JBR A;  2QR4 A;  1IVH A;  4L3Z A;  1SK6 A;  2R0N A;  1RP3 A;  3NF4 A;  4X28 C;  2VR0 A;  1RJ1 A;  3BNH A;  2RDZ A;  2BU2 A;  3BNF A;  3L1T A;  4L1F A;  5BRM A;  3Q23 A;  4AKG A;  2YYM A;  2VIG A;  2FP2 A;  1R2J A;  2ZAF A;  3M9V A;  4FZ4 A;  4HR3 A;  4L38 A;  2YYK A;  3D9E A;  4J1V A;  5K3J A;  3SXQ A;  1FS8 A;  1QDB A;  1XFW A;  2YYJ A;  4LQS B;  4AKH A;  1JM6 A;  1FS9 A;  5J6A A;  3MPI A;  1K90 A;  4IV6 A;  4X28 A;  2CJ7 A;  1Y8O A;  2A1T A;  2UXW A;  3MXL A;  3VAD A;  5B6B A;  1S26 A;  2R05 A;  3KML A;  4XVX A;  2RF7 A;  3MMO A;  2DVL A;  3FCJ A;  4LQQ B;  4E00 A;  2BU6 A;  2EBA A;  4W9U A;  3SCE A;  3Q22 A;  2OEV A;  3OWA A;  3N0R A;  5GJW E;  2Q8I A;  4O5M A;  5M4P A;  2OT4 A;  1GKZ A;  2BU8 A;  4H7Q A;  4Q17 A;  3AFF A;  4MP2 A;  4QIC A;  4E01 A;  2WBI A;  3SWO A;  4FF1 A;  3BNJ A;  2DDH A;  4Q5C A;  3R7K A;  1X8Z A;  2CJ5 A;  3AFE A;  1T9G A;  3D2R A;  4Q1O A;  4G5E A;  3HWC A;  3OIB A;  3Q0A A;  1EGE A;  3OWM A;  4KSF A;  2FP1 A;  4AI6 A;  4HKR A;  2YYI A;  2CJ4 A;  3GQT A;  1JQI A;  4MPC A;  1LVC A;  4M9A A;  3PFD A;  1UDY A;  1K93 A;  3CRL A;  5GJV E;  2EBF X;  2OR0 A;  3MPJ A;  3S7W A;  3TOR A;  2HJN A;  3TTB A;  4FF3 A;  1PI1 A;  2PO4 A;  2AZE A;  3RKH A;  3TZ4 A;  4E02 A;  3II9 A;  1BUC A;  4Q4U A;  1Y8P A;  2CX9 A;  4AKI A;  2BU7 A;  3P4T A;  4ZXV A;  2R03 A;  1W07 A;  3MDE A;  3D1I A;  2CJ6 A;  5J71 A;  3CE2 A;  2ZO5 A;  3D9G A;  3EON A;  3LGQ A;  4Q0T A;  3UBR A;  1K8T A;  2XQR B;  5B5V A; 
#chains in the Genus database with same CATH homology
 3Q23 A;  4KSF A;  1XFZ A;  2FP1 A;  2LFW A;  4AI6 A;  4HKR A;  4AKG A;  2FP2 A;  4FZ4 A;  3C2P A;  3VKH A;  3C46 A;  1LVC A;  3Q24 A;  4AKH A;  1XFW A;  1Y0V A;  1K93 A;  5GJV E;  4F0X A;  2EBF X;  1K90 A;  4FF4 A;  1PK0 A;  2PO4 A;  4FF3 A;  2AZE A;  3X29 A;  1S26 A;  3KML A;  3C3L A;  3VKG A;  2YGW A;  1XFU A;  4G97 A;  3Q22 A;  2VF1 A;  1XFX A;  4AKI A;  2F6L A;  4KSA A;  3N0R A;  5GJW E;  4FF2 A;  2EBH X;  1SC5 A;  2GBB A;  4HKS A;  4QIC A;  2EC5 A;  4KS9 A;  2AO2 A;  3CE2 A;  2QR4 A;  4FF1 A;  1SK6 A;  1RP3 A;  1XFV A;  1K8T A;  4P79 A;  1XFY A;  3Q0A A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...