2AZEA

Structure of the rb c-terminal domain bound to an e2f1-dp1 heterodimer
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
149
structure length
149
Chain Sequence
FAQECQNLEVERQRRLERIKQKQSQLQELILQQIAFKNLVQRNRHAEQQASRPPPPNSVIHLPFIIVNTSKKTVIDCSISNDKFEYLFNFDNTFEIHDDIEVLKRMGMACGLESGSCSAEDLKMARSLVPKALEPYVTEMAQGTVGGVF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Transcription factor Dp-1
publication title Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Cell cycle, transcription
total genus 41
structure length 149
sequence length 149
ec nomenclature
pdb deposition date 2005-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08781 DP Transcription factor DP
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.140.80 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A; domain 3 2azeA01
2AZEA
chains in the Genus database with same CATH superfamily
2YYJA 2AO2A 2FP1A 2RFQA 4MP7A 1K93A 4ZYJA 5J6AA 5K3IA 1BUCA 5M4MA 1S26A 3RKHA 1FS9A 2C12A 4HKSA 3C3LA 1EGEA 3TTBA 3PFDA 2D29A 2UXWA 4MPEA 4H81A 1SIRA 4NXLA 1XFWA 4W9UA 2R02A 3EONA 2E80A 4IRNA 3TZ0A 1U8VA 2YYIA 4J1VA 4U83A 4AKGA 3VKGA 3MMOA 3MPIA 4P13A 3S7WA 1RJ4A 2ZAFA 3KMLA 4JEKA 3F29A 3GNCA 2Q8FA 4Q17A 2BU7A 3Q23A 2JBSA 4H7QA 1X8ZA 3SWOA 4FF1A 4HR3A 1X91A 4DZYA 4LQQB 5K3GA 1LVCA 3L1TA 4G97A 3SCEA 2XQRB 4KSFA 1GU6A 3VADA 5M4PA 4L3YA 4IV6A 5B5VA 4QICA 1XFUA 2WBIA 3HWCA 4KSAA 1GJVA 2OEXA 3MKHA 1QDBA 4XVXA 1XFXA 4G5EA 2OJQA 2ZO5A 3FCJA 3UBRA 4E02A 2R05A 3D2RA 4Q1OA 2RDZA 2ZDYA 4O5MA 5M4KA 1W07A 3BNGA 4MPCA 4KCFA 3II9A 3TZ4A 1XFYA 2E0AA 2GBBA 2R0NA 4WJYA 4H85A 1GKXA 2J7AA 1OAHA 2R03A 4JIOA 2E81A 2YYGA 2Z1QA 2VR0A 4L3ZA 2BU2A 3MPJA 1XFZA 4FZ4A 3GQTA 4L38A 5BRKA 2CJ4A 2EBAA 1IS2A 3SF6A 3M9VA 2YYLA 2Q8HA 2CJ5A 4HKRA 4DOYA 3BNFA 2EC5A 2JIFA 3BNJA 3R7KA 4F0XA 4AKIA 3AFFA 4V25A 4ZXVA 2PNRA 3X29A 1XG2B 4L1FA 1R2JA 1R3BA 1WS9A 2XS1A 2OT4A 2CX9A 3B96A 1JM6A 3N0RA 3Q22A 3TZ2A 1K90A 1RP3A 1FS8A 1Y8OA 2YYMA 4E00A 4AI6A 3FO3A 2Q8IA 1Y8NA 3UU9A 3GM6A 1GKZA 4P79A 3LGQA 3P4TA 2HJNA 4LQSB 4N5FA 2YYKA 5K3JA 3X0XA 5BRMA 5K3HA 4FF2A 2Q8GA 2C0UA 4AKHA 2RF7A 2VF1A 2XS8A 4FF3A 3TORA 2REHA 4MP2A 2DDHA 1T9GA 2IX6A 2JBTA 2DVLA 3MXLA 1SC5A 4KTOA 4OO2A 1PI1A 2VIGA 3D9DA 5GJWE 5GJVE 1IVHA 4E01A 4M9AA 5B5WA 2OR0A 2JBRA 2A1TA 2EBFX 1FS7A 2R0MA 4Q0TA 2BU5A 4X28C 2BTZA 4Q5CA 2CJ8A 3X0YA 2PO4A 3Q0AA 2F6LA 1UDYA 1EGCA 2EBHX 2FP2A 3CRKA 4L3XA 3TZ5A 1PK0A 3OWAA 5B6BA 5J71A 2FONA 3BNHA 3D9EA 2PG0A 2CJ6A 3CRLA 3C2PA 4X28A 1Y0VA 3C46A 3SXQA 1RX0A 2AZEA 1K8TA 2OEVA 3D9GA 4Q5BA 4Q4UA 1X90A 2QR4A 3MDEA 2BU8A 4JIZA 3NF4A 4MPNA 3D1IA 2ZKJA 3D6BA 3LG1A 1Y8PA 1RJ1A 3OIBA 1EGDA 1JQIA 3D9FA 3MDDA 4RM7A 2YGWA 1SIQA 2CJ7A 2ZDXA 3EOMA 4V26A 2IX5A 5M4NA 1SK6A 3Q24A 2BU6A 2LFWA 4FF4A 3AFEA 4KS9A 1XFVA 3OWMA 1UKWA 3VKHA 3CE2A
chains in the Genus database with same CATH topology
1SC5A 2AO2A 2FP1A 5GJWE 5GJVE 2EC5A 4AKIA 1K93A 4F0XA 4QICA 1XFUA 3X29A 2EBFX 4KSAA 3VKHA 1S26A 1XFXA 4HKSA 3C3LA 2PO4A 3Q0AA 2F6LA 2EBHX 2FP2A 3N0RA 1K90A 3Q22A 3Q24A 1PK0A 1RP3A 1XFWA 1XFYA 3C2PA 2GBBA 3C46A 1Y0VA 4AI6A 2AZEA 1K8TA 3VKGA 2QR4A 4AKGA 4P79A 3KMLA 4FF2A 3Q23A 2YGWA 1XFZA 4FZ4A 4FF1A 4AKHA 4FF4A 1SK6A 2VF1A 2LFWA 1LVCA 4KS9A 4G97A 4FF3A 1XFVA 4KSFA 4HKRA 3CE2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AZE A; 
#chains in the Genus database with same CATH topology
 2YYJ A;  2AO2 A;  2FP1 A;  2RFQ A;  4MP7 A;  1K93 A;  4ZYJ A;  5J6A A;  5K3I A;  1BUC A;  5M4M A;  1S26 A;  3RKH A;  1FS9 A;  2C12 A;  4HKS A;  3C3L A;  1EGE A;  3TTB A;  3PFD A;  2D29 A;  2UXW A;  4MPE A;  4H81 A;  1SIR A;  4NXL A;  1XFW A;  4W9U A;  2R02 A;  3EON A;  2E80 A;  4IRN A;  3TZ0 A;  1U8V A;  2YYI A;  4J1V A;  4U83 A;  4AKG A;  3VKG A;  3MMO A;  3MPI A;  4P13 A;  3S7W A;  1RJ4 A;  2ZAF A;  3KML A;  4JEK A;  3F29 A;  3GNC A;  2Q8F A;  4Q17 A;  2BU7 A;  3Q23 A;  2JBS A;  4H7Q A;  1X8Z A;  3SWO A;  4FF1 A;  4HR3 A;  1X91 A;  4DZY A;  4LQQ B;  5K3G A;  1LVC A;  3L1T A;  4G97 A;  3SCE A;  2XQR B;  4KSF A;  1GU6 A;  3VAD A;  5M4P A;  4L3Y A;  4IV6 A;  5B5V A;  4QIC A;  1XFU A;  2WBI A;  3HWC A;  4KSA A;  1GJV A;  2OEX A;  3MKH A;  1QDB A;  4XVX A;  1XFX A;  4G5E A;  2OJQ A;  2ZO5 A;  3FCJ A;  3UBR A;  4E02 A;  2R05 A;  3D2R A;  4Q1O A;  2RDZ A;  2ZDY A;  4O5M A;  5M4K A;  1W07 A;  3BNG A;  4MPC A;  4KCF A;  3II9 A;  3TZ4 A;  1XFY A;  2E0A A;  2GBB A;  2R0N A;  4WJY A;  4H85 A;  1GKX A;  2J7A A;  1OAH A;  2R03 A;  4JIO A;  2E81 A;  2YYG A;  2Z1Q A;  2VR0 A;  4L3Z A;  2BU2 A;  3MPJ A;  1XFZ A;  4FZ4 A;  3GQT A;  4L38 A;  5BRK A;  2CJ4 A;  2EBA A;  1IS2 A;  3SF6 A;  3M9V A;  2YYL A;  2Q8H A;  2CJ5 A;  4HKR A;  4DOY A;  3BNF A;  2EC5 A;  2JIF A;  3BNJ A;  3R7K A;  4F0X A;  4AKI A;  3AFF A;  4V25 A;  4ZXV A;  2PNR A;  3X29 A;  1XG2 B;  4L1F A;  1R2J A;  1R3B A;  1WS9 A;  2XS1 A;  2OT4 A;  2CX9 A;  3B96 A;  1JM6 A;  3N0R A;  3Q22 A;  3TZ2 A;  1K90 A;  1RP3 A;  1FS8 A;  1Y8O A;  2YYM A;  4E00 A;  4AI6 A;  3FO3 A;  2Q8I A;  1Y8N A;  3UU9 A;  3GM6 A;  1GKZ A;  4P79 A;  3LGQ A;  3P4T A;  2HJN A;  4LQS B;  4N5F A;  2YYK A;  5K3J A;  3X0X A;  5BRM A;  5K3H A;  4FF2 A;  2Q8G A;  2C0U A;  4AKH A;  2RF7 A;  2VF1 A;  2XS8 A;  4FF3 A;  3TOR A;  2REH A;  4MP2 A;  2DDH A;  1T9G A;  2IX6 A;  2JBT A;  2DVL A;  3MXL A;  1SC5 A;  4KTO A;  4OO2 A;  1PI1 A;  2VIG A;  3D9D A;  5GJW E;  5GJV E;  1IVH A;  4E01 A;  4M9A A;  5B5W A;  2OR0 A;  2JBR A;  2A1T A;  2EBF X;  1FS7 A;  2R0M A;  4Q0T A;  2BU5 A;  4X28 C;  2BTZ A;  4Q5C A;  2CJ8 A;  3X0Y A;  2PO4 A;  3Q0A A;  2F6L A;  1UDY A;  1EGC A;  2EBH X;  2FP2 A;  3CRK A;  4L3X A;  3TZ5 A;  1PK0 A;  3OWA A;  5B6B A;  5J71 A;  2FON A;  3BNH A;  3D9E A;  2PG0 A;  2CJ6 A;  3CRL A;  3C2P A;  4X28 A;  1Y0V A;  3C46 A;  3SXQ A;  1RX0 A;  2AZE A;  1K8T A;  2OEV A;  3D9G A;  4Q5B A;  4Q4U A;  1X90 A;  2QR4 A;  3MDE A;  2BU8 A;  4JIZ A;  3NF4 A;  4MPN A;  3D1I A;  2ZKJ A;  3D6B A;  3LG1 A;  1Y8P A;  1RJ1 A;  3OIB A;  1EGD A;  1JQI A;  3D9F A;  3MDD A;  4RM7 A;  2YGW A;  1SIQ A;  2CJ7 A;  2ZDX A;  3EOM A;  4V26 A;  2IX5 A;  5M4N A;  1SK6 A;  3Q24 A;  2BU6 A;  2LFW A;  4FF4 A;  3AFE A;  4KS9 A;  1XFV A;  3OWM A;  1UKW A;  3VKH A;  3CE2 A; 
#chains in the Genus database with same CATH homology
 1SC5 A;  2AO2 A;  2FP1 A;  5GJW E;  5GJV E;  2EC5 A;  4AKI A;  1K93 A;  4F0X A;  4QIC A;  1XFU A;  3X29 A;  2EBF X;  4KSA A;  3VKH A;  1S26 A;  1XFX A;  4HKS A;  3C3L A;  2PO4 A;  3Q0A A;  2F6L A;  2EBH X;  2FP2 A;  3N0R A;  1K90 A;  3Q22 A;  3Q24 A;  1PK0 A;  1RP3 A;  1XFW A;  1XFY A;  3C2P A;  2GBB A;  3C46 A;  1Y0V A;  4AI6 A;  2AZE A;  1K8T A;  3VKG A;  2QR4 A;  4AKG A;  4P79 A;  3KML A;  4FF2 A;  3Q23 A;  2YGW A;  1XFZ A;  4FZ4 A;  4FF1 A;  4AKH A;  4FF4 A;  1SK6 A;  2VF1 A;  2LFW A;  1LVC A;  4KS9 A;  4G97 A;  4FF3 A;  1XFV A;  4KSF A;  4HKR A;  3CE2 A; 
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similar chains in the Genus database (?% sequence similarity)
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