4X28A

Crystal structure of the chse4-chse5 complex from mycobacterium tuberculosis
Total Genus 129
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
129
sequence length
399
structure length
386
Chain Sequence
b'MRISYTPQQEELRRELRSYFATLMTPERREALSSVNVYRETIAQMGRDGWLALGWPKEYGGQGRSAMDQLIFTDEAAIAGAPVPFLTINSVAPTIMAYGTDEQKRFFLPRIAAGDLHFSIGYSEPGAGTDLANLRTTAVRDGDDYVVNGQKMWTSLIQYADYVWLAVRTNPESSGAKKHRGISVLIVPTTAEGFSWTPVHTMAGPDTSATYYSDVRVPVANRVGEENAGWKLVTNQLNHERVALVSPAPIFGCLREVREWAQNTKDAGGTRLIDSEWVQLNLARVHAKAEVLKLINWELASSQGPSPADASAAKVFGTELATEAYRLLMEVLGTAATLRQNSPGALLRGRVERMHRACLILTFGGGTNEVQRDIIGMVALGLPRAN'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Acyl-CoA dehydrogenase
publication title Unraveling Cholesterol Catabolism in Mycobacterium tuberculosis: ChsE4-ChsE5 alpha 2 beta 2 Acyl-CoA Dehydrogenase Initiates beta-Oxidation of 3-Oxo-cholest-4-en-26-oyl CoA.
pubmed doi rcsb
source organism Mycobacterium tuberculosis (strain atcc 25618 / h37rv)
molecule tags Oxidoreductase
total genus 129
structure length 386
sequence length 399
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 4x28A01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 4x28A03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 4x28A02
4WJYA 2REHA 2R0NA 3MXLA 2YYGA 2EBAA 2IX6A 2DVLA 3SXQA 5K3IA 2RFQA 2WBIA 4Q5BA 2JIFA 2CX9A 3X0YA 4L3ZA 4HR3A 4Q0TA 3EOMA 1FS9A 4Q1OA 2DDHA 1WS9A 1SIRA 2D29A 2OR0A 3OWMA 5K3GA 4L3XA 3MPIA 3HWCA 4DOYA 3D9FA 3AFFA 3SF6A 1GU6A 4L1FA 3P4TA 4NXLA 4OO2A 1IVHA 4X28A 2OT4A 3SWOA 3NF4A 3BNGA 2E81A 3GQTA 3D9GA 4U83A 3BNFA 4M9AA 2YYMA 3UU9A 1U8VA 2Z1QA 3LGQA 2JBSA 2IX5A 2J7AA 2R0MA 3M9VA 3D6BA 1OAHA 3GNCA 2UXWA 3MMOA 3EONA 3OWAA 4N5FA 3MKHA 3L1TA 3MDDA 2JBTA 2RDZA 3D1IA 4Q4UA 3MDEA 3D9DA 4P13A 4RM7A 3LG1A 4IRNA 4KTOA 3TORA 1JQIA 4Q5CA 1W07A 1SIQA 1R2JA 4IV6A 4L3YA 3B96A 4O5MA 4W9UA 2VR0A 1BUCA 3BNHA 1RX0A 3II9A 3OIBA 1FS8A 3RKHA 5K3HA 1EGEA 3X0XA 4Q17A 1UDYA 2YYJA 1IS2A 2ZAFA 3FCJA 3R7KA 4ZYJA 3MPJA 3AFEA 2YYLA 2FONA 1FS7A 2E80A 4JEKA 1EGDA 3TTBA 3PFDA 3FO3A 4G5EA 1T9GA 3UBRA 1EGCA 4KCFA 2YYIA 3S7WA 3GM6A 2RF7A 4L38A 3SCEA 2A1TA 2JBRA 5K3JA 2PG0A 4ZXVA 3BNJA 4XVXA 1UKWA 2VIGA 4X28C 3D9EA 2ZO5A 3F29A 2C0UA 2C12A 2YYKA 1QDBA
chains in the Genus database with same CATH superfamily
4WJYA 2EBFX 3Q0AA 2REHA 2R0NA 4F0XA 3MXLA 2ZKJA 2YYGA 4E00A 2HJNA 1PK0A 2EBAA 2IX6A 4JIZA 3TZ2A 2BU8A 1XFYA 3VADA 5EZ3A 2DVLA 2EBHX 4P79A 5BRMA 4FF2A 3SXQA 4AKIA 2YGWA 5K3IA 2QR4A 2RFQA 2WBIA 4Q5BA 5B6BA 3U33A 2AZEA 2JIFA 2CX9A 3X0YA 1JM6A 4HR3A 4L3ZA 3EOMA 4Q0TA 1FS9A 4FF4A 4Q1OA 2DDHA 1XFWA 2OJQA 1WS9A 1SIRA 2D29A 3DJLA 2OR0A 3OWMA 5K3GA 2LFWA 1SC5A 3MPIA 1SK6A 2R02A 4DOYA 2XS1A 3D9FA 3AFFA 3HWCA 4MPEA 3SF6A 4MPNA 1PI1A 1GU6A 4L1FA 3P4TA 2R05A 1K90A 2FP2A 4MP7A 3TZ0A 5M4NA 4NXLA 1X91A 4OO2A 1IVHA 5M4PA 1Y8OA 4X28A 2ZDYA 1GKZA 3SWOA 4HKRA 3NF4A 2OT4A 3BNGA 3C2PA 4AKHA 2CJ7A 2E81A 5J71A 3GQTA 3D9GA 2EC5A 4U83A 4FZ4A 5GJVE 3BNFA 4E01A 4M9AA 2XS8A 2YYMA 1Y0VA 3N0RA 3UU9A 1U8VA 2PO4A 2Z1QA 3KMLA 3LGQA 2JBSA 1X90A 2R03A 2IX5A 1XFXA 2BU6A 2R0MA 2J7AA 4QICA 2CJ8A 3M9VA 1XFUA 2OEVA 3CE2A 4FF1A 4H7QA 2CJ5A 3D6BA 1OAHA 3GNCA 2UXWA 2OEXA 4J1VA 3MMOA 3EONA 3OWAA 2XQRB 4N5FA 3MKHA 3X29A 3L1TA 3MDDA 5J6AA 2JBTA 1XG2B 2RDZA 3D1IA 2Q8GA 4Q4UA 3MDEA 3D9DA 4P13A 4RM7A 3LG1A 4MP2A 4IRNA 3TZ4A 3C46A 2BU7A 4KTOA 1GKXA 3TORA 1S26A 4LQSB 5B5WA 1JQIA 3VKHA 4HKSA 4Q5CA 1W07A 2BTZA 2GBBA 4KSAA 4V25A 2F6LA 2Q8FA 4DZYA 1SIQA 1R2JA 1K8TA 4IV6A 4L3YA 3CRKA 4V26A 3B96A 4O5MA 4W9UA 2VR0A 1BUCA 3CRLA 4LQQB 3BNHA 1RX0A 3II9A 4KS9A 4E02A 1R3BA 3OIBA 1FS8A 1GJVA 4L3XA 3RKHA 3Q23A 5K3HA 2BU2A 1EGEA 3X0XA 4Q17A 1UDYA 3D2RA 1K93A 4AI6A 1LVCA 2YYJA 1IS2A 2ZAFA 3FCJA 3R7KA 4ZYJA 5M4MA 3MPJA 3AFEA 4KSFA 2YYLA 2FONA 1FS7A 2E80A 4JEKA 1RP3A 1RJ1A 3TZ5A 1EGDA 3TTBA 3PFDA 3FO3A 4G5EA 4FF3A 1T9GA 3UBRA 4JIOA 4G97A 1EGCA 4KCFA 2YYIA 3S7WA 4H85A 3GM6A 2RF7A 4L38A 3SCEA 2A1TA 3Q24A 2JBRA 4H81A 5K3JA 1XFVA 5B5VA 2PG0A 2Q8HA 2AO2A 1Y8PA 2BU5A 4ZXVA 1XFZA 2PNRA 2FP1A 3BNJA 3Q22A 3C3LA 4XVXA 1Y8NA 1UKWA 2VIGA 5BRKA 5M4KA 2VF1A 1X8ZA 1RJ4A 2E0AA 4AKGA 2CJ6A 4X28C 2ZDXA 4MPCA 3D9EA 5GJWE 3VKGA 2ZO5A 2Q8IA 3F29A 2CJ4A 2C0UA 2C12A 2YYKA 1QDBA
chains in the Genus database with same CATH topology
4WJYA 2REHA 2R0NA 3MXLA 2YYGA 2EBAA 2IX6A 2DVLA 3SXQA 5K3IA 2RFQA 2WBIA 4Q5BA 2JIFA 2CX9A 3X0YA 4L3ZA 4HR3A 4Q0TA 3EOMA 1FS9A 4Q1OA 2DDHA 1WS9A 1SIRA 2D29A 2OR0A 3OWMA 5K3GA 4L3XA 3MPIA 3HWCA 4DOYA 3D9FA 3AFFA 3SF6A 1GU6A 4L1FA 3P4TA 4NXLA 4OO2A 1IVHA 4X28A 2OT4A 3SWOA 3NF4A 3BNGA 2E81A 3GQTA 3D9GA 4U83A 3BNFA 4M9AA 2YYMA 3UU9A 1U8VA 2Z1QA 3LGQA 2JBSA 2IX5A 2J7AA 2R0MA 3M9VA 3D6BA 1OAHA 3GNCA 2UXWA 3MMOA 3EONA 3OWAA 4N5FA 3MKHA 3L1TA 3MDDA 2JBTA 2RDZA 3D1IA 4Q4UA 3MDEA 3D9DA 4P13A 4RM7A 3LG1A 4IRNA 4KTOA 3TORA 1JQIA 4Q5CA 1W07A 1SIQA 1R2JA 4IV6A 4L3YA 3B96A 4O5MA 4W9UA 2VR0A 1BUCA 3BNHA 1RX0A 3II9A 3OIBA 1FS8A 3RKHA 5K3HA 1EGEA 3X0XA 4Q17A 1UDYA 2YYJA 1IS2A 2ZAFA 3FCJA 3R7KA 4ZYJA 3MPJA 3AFEA 2YYLA 2FONA 1FS7A 2E80A 4JEKA 1EGDA 3TTBA 3PFDA 3FO3A 4G5EA 1T9GA 3UBRA 1EGCA 4KCFA 2YYIA 3S7WA 3GM6A 2RF7A 4L38A 3SCEA 2A1TA 2JBRA 5K3JA 2PG0A 4ZXVA 3BNJA 4XVXA 1UKWA 2VIGA 4X28C 3D9EA 2ZO5A 3F29A 2C0UA 2C12A 2YYKA 1QDBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WJY A;  2REH A;  2R0N A;  3MXL A;  2YYG A;  2EBA A;  2IX6 A;  2DVL A;  3SXQ A;  5K3I A;  2RFQ A;  2WBI A;  4Q5B A;  2JIF A;  2CX9 A;  3X0Y A;  4L3Z A;  4HR3 A;  4Q0T A;  3EOM A;  1FS9 A;  4Q1O A;  2DDH A;  1WS9 A;  1SIR A;  2D29 A;  2OR0 A;  3OWM A;  5K3G A;  4L3X A;  3MPI A;  3HWC A;  4DOY A;  3D9F A;  3AFF A;  3SF6 A;  1GU6 A;  4L1F A;  3P4T A;  4NXL A;  4OO2 A;  1IVH A;  4X28 A;  2OT4 A;  3SWO A;  3NF4 A;  3BNG A;  2E81 A;  3GQT A;  3D9G A;  4U83 A;  3BNF A;  4M9A A;  2YYM A;  3UU9 A;  1U8V A;  2Z1Q A;  3LGQ A;  2JBS A;  2IX5 A;  2J7A A;  2R0M A;  3M9V A;  3D6B A;  1OAH A;  3GNC A;  2UXW A;  3MMO A;  3EON A;  3OWA A;  4N5F A;  3MKH A;  3L1T A;  3MDD A;  2JBT A;  2RDZ A;  3D1I A;  4Q4U A;  3MDE A;  3D9D A;  4P13 A;  4RM7 A;  3LG1 A;  4IRN A;  4KTO A;  3TOR A;  1JQI A;  4Q5C A;  1W07 A;  1SIQ A;  1R2J A;  4IV6 A;  4L3Y A;  3B96 A;  4O5M A;  4W9U A;  2VR0 A;  1BUC A;  3BNH A;  1RX0 A;  3II9 A;  3OIB A;  1FS8 A;  3RKH A;  5K3H A;  1EGE A;  3X0X A;  4Q17 A;  1UDY A;  2YYJ A;  1IS2 A;  2ZAF A;  3FCJ A;  3R7K A;  4ZYJ A;  3MPJ A;  3AFE A;  2YYL A;  2FON A;  1FS7 A;  2E80 A;  4JEK A;  1EGD A;  3TTB A;  3PFD A;  3FO3 A;  4G5E A;  1T9G A;  3UBR A;  1EGC A;  4KCF A;  2YYI A;  3S7W A;  3GM6 A;  2RF7 A;  4L38 A;  3SCE A;  2A1T A;  2JBR A;  5K3J A;  2PG0 A;  4ZXV A;  3BNJ A;  4XVX A;  1UKW A;  2VIG A;  4X28 C;  3D9E A;  2ZO5 A;  3F29 A;  2C0U A;  2C12 A;  2YYK A;  1QDB A; 
#chains in the Genus database with same CATH topology
 4WJY A;  2EBF X;  3Q0A A;  2REH A;  2R0N A;  4F0X A;  3MXL A;  2ZKJ A;  2YYG A;  4E00 A;  2HJN A;  1PK0 A;  2EBA A;  2IX6 A;  4JIZ A;  3TZ2 A;  2BU8 A;  1XFY A;  3VAD A;  5EZ3 A;  2DVL A;  2EBH X;  4P79 A;  5BRM A;  4FF2 A;  3SXQ A;  4AKI A;  2YGW A;  5K3I A;  2QR4 A;  2RFQ A;  2WBI A;  4Q5B A;  5B6B A;  3U33 A;  2AZE A;  2JIF A;  2CX9 A;  3X0Y A;  1JM6 A;  4HR3 A;  4L3Z A;  3EOM A;  4Q0T A;  1FS9 A;  4FF4 A;  4Q1O A;  2DDH A;  1XFW A;  2OJQ A;  1WS9 A;  1SIR A;  2D29 A;  3DJL A;  2OR0 A;  3OWM A;  5K3G A;  2LFW A;  1SC5 A;  3MPI A;  1SK6 A;  2R02 A;  4DOY A;  2XS1 A;  3D9F A;  3AFF A;  3HWC A;  4MPE A;  3SF6 A;  4MPN A;  1PI1 A;  1GU6 A;  4L1F A;  3P4T A;  2R05 A;  1K90 A;  2FP2 A;  4MP7 A;  3TZ0 A;  5M4N A;  4NXL A;  1X91 A;  4OO2 A;  1IVH A;  5M4P A;  1Y8O A;  4X28 A;  2ZDY A;  1GKZ A;  3SWO A;  4HKR A;  3NF4 A;  2OT4 A;  3BNG A;  3C2P A;  4AKH A;  2CJ7 A;  2E81 A;  5J71 A;  3GQT A;  3D9G A;  2EC5 A;  4U83 A;  4FZ4 A;  5GJV E;  3BNF A;  4E01 A;  4M9A A;  2XS8 A;  2YYM A;  1Y0V A;  3N0R A;  3UU9 A;  1U8V A;  2PO4 A;  2Z1Q A;  3KML A;  3LGQ A;  2JBS A;  1X90 A;  2R03 A;  2IX5 A;  1XFX A;  2BU6 A;  2R0M A;  2J7A A;  4QIC A;  2CJ8 A;  3M9V A;  1XFU A;  2OEV A;  3CE2 A;  4FF1 A;  4H7Q A;  2CJ5 A;  3D6B A;  1OAH A;  3GNC A;  2UXW A;  2OEX A;  4J1V A;  3MMO A;  3EON A;  3OWA A;  2XQR B;  4N5F A;  3MKH A;  3X29 A;  3L1T A;  3MDD A;  5J6A A;  2JBT A;  1XG2 B;  2RDZ A;  3D1I A;  2Q8G A;  4Q4U A;  3MDE A;  3D9D A;  4P13 A;  4RM7 A;  3LG1 A;  4MP2 A;  4IRN A;  3TZ4 A;  3C46 A;  2BU7 A;  4KTO A;  1GKX A;  3TOR A;  1S26 A;  4LQS B;  5B5W A;  1JQI A;  3VKH A;  4HKS A;  4Q5C A;  1W07 A;  2BTZ A;  2GBB A;  4KSA A;  4V25 A;  2F6L A;  2Q8F A;  4DZY A;  1SIQ A;  1R2J A;  1K8T A;  4IV6 A;  4L3Y A;  3CRK A;  4V26 A;  3B96 A;  4O5M A;  4W9U A;  2VR0 A;  1BUC A;  3CRL A;  4LQQ B;  3BNH A;  1RX0 A;  3II9 A;  4KS9 A;  4E02 A;  1R3B A;  3OIB A;  1FS8 A;  1GJV A;  4L3X A;  3RKH A;  3Q23 A;  5K3H A;  2BU2 A;  1EGE A;  3X0X A;  4Q17 A;  1UDY A;  3D2R A;  1K93 A;  4AI6 A;  1LVC A;  2YYJ A;  1IS2 A;  2ZAF A;  3FCJ A;  3R7K A;  4ZYJ A;  5M4M A;  3MPJ A;  3AFE A;  4KSF A;  2YYL A;  2FON A;  1FS7 A;  2E80 A;  4JEK A;  1RP3 A;  1RJ1 A;  3TZ5 A;  1EGD A;  3TTB A;  3PFD A;  3FO3 A;  4G5E A;  4FF3 A;  1T9G A;  3UBR A;  4JIO A;  4G97 A;  1EGC A;  4KCF A;  2YYI A;  3S7W A;  4H85 A;  3GM6 A;  2RF7 A;  4L38 A;  3SCE A;  2A1T A;  3Q24 A;  2JBR A;  4H81 A;  5K3J A;  1XFV A;  5B5V A;  2PG0 A;  2Q8H A;  2AO2 A;  1Y8P A;  2BU5 A;  4ZXV A;  1XFZ A;  2PNR A;  2FP1 A;  3BNJ A;  3Q22 A;  3C3L A;  4XVX A;  1Y8N A;  1UKW A;  2VIG A;  5BRK A;  5M4K A;  2VF1 A;  1X8Z A;  1RJ4 A;  2E0A A;  4AKG A;  2CJ6 A;  4X28 C;  2ZDX A;  4MPC A;  3D9E A;  5GJW E;  3VKG A;  2ZO5 A;  2Q8I A;  3F29 A;  2CJ4 A;  2C0U A;  2C12 A;  2YYK A;  1QDB A; 
#chains in the Genus database with same CATH homology
 4WJY A;  2REH A;  2R0N A;  3MXL A;  2YYG A;  2EBA A;  2IX6 A;  2DVL A;  3SXQ A;  5K3I A;  2RFQ A;  2WBI A;  4Q5B A;  2JIF A;  2CX9 A;  3X0Y A;  4L3Z A;  4HR3 A;  4Q0T A;  3EOM A;  1FS9 A;  4Q1O A;  2DDH A;  1WS9 A;  1SIR A;  2D29 A;  2OR0 A;  3OWM A;  5K3G A;  4L3X A;  3MPI A;  3HWC A;  4DOY A;  3D9F A;  3AFF A;  3SF6 A;  1GU6 A;  4L1F A;  3P4T A;  4NXL A;  4OO2 A;  1IVH A;  4X28 A;  2OT4 A;  3SWO A;  3NF4 A;  3BNG A;  2E81 A;  3GQT A;  3D9G A;  4U83 A;  3BNF A;  4M9A A;  2YYM A;  3UU9 A;  1U8V A;  2Z1Q A;  3LGQ A;  2JBS A;  2IX5 A;  2J7A A;  2R0M A;  3M9V A;  3D6B A;  1OAH A;  3GNC A;  2UXW A;  3MMO A;  3EON A;  3OWA A;  4N5F A;  3MKH A;  3L1T A;  3MDD A;  2JBT A;  2RDZ A;  3D1I A;  4Q4U A;  3MDE A;  3D9D A;  4P13 A;  4RM7 A;  3LG1 A;  4IRN A;  4KTO A;  3TOR A;  1JQI A;  4Q5C A;  1W07 A;  1SIQ A;  1R2J A;  4IV6 A;  4L3Y A;  3B96 A;  4O5M A;  4W9U A;  2VR0 A;  1BUC A;  3BNH A;  1RX0 A;  3II9 A;  3OIB A;  1FS8 A;  3RKH A;  5K3H A;  1EGE A;  3X0X A;  4Q17 A;  1UDY A;  2YYJ A;  1IS2 A;  2ZAF A;  3FCJ A;  3R7K A;  4ZYJ A;  3MPJ A;  3AFE A;  2YYL A;  2FON A;  1FS7 A;  2E80 A;  4JEK A;  1EGD A;  3TTB A;  3PFD A;  3FO3 A;  4G5E A;  1T9G A;  3UBR A;  1EGC A;  4KCF A;  2YYI A;  3S7W A;  3GM6 A;  2RF7 A;  4L38 A;  3SCE A;  2A1T A;  2JBR A;  5K3J A;  2PG0 A;  4ZXV A;  3BNJ A;  4XVX A;  1UKW A;  2VIG A;  4X28 C;  3D9E A;  2ZO5 A;  3F29 A;  2C0U A;  2C12 A;  2YYK A;  1QDB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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