4HKSA

Calcium release-activated calcium (crac) channel orai, k163w mutant
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
191
structure length
165
Chain Sequence
TYLSWRKLQLSRAKLKASSWTSALLSGFAMVAMVEVQMLIAFAICTTLLVAVHMLALMISTCILPNPHERLHWYIETAWAFSTLLGLILFLLEIAILCWVKFYDLSRRAAWSATVVLIPVMIIFMAFAIHFYRSLVSHKYEVTVSGIRELEMLKEQMEQDHLEHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein
molecule keywords Calcium release-activated calcium channel protein 1
publication title Crystal structure of the calcium release-activated calcium channel Orai.
pubmed doi rcsb
source organism Drosophila melanogaster
total genus 65
structure length 165
sequence length 191
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07856 Orai-1 Mediator of CRAC channel activity
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.140.140 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A; domain 3 4hksA00
4HKSA 4HKRA
chains in the Genus database with same CATH superfamily
1Y8NA 3R7KA 1R3BA 2AZEA 1RX0A 4WJYA 3X0YA 4FF1A 2CJ8A 2OEXA 2RF7A 3TZ2A 2J7AA 4JEKA 1JM6A 1Y0VA 3TZ0A 3Q22A 3CE2A 3VADA 4FF3A 4OO2A 4JIZA 2JBSA 4ZYJA 4H85A 1XG2B 3HWCA 1RJ4A 3AFEA 2IX5A 4FZ4A 1K8TA 2Z1QA 1K90A 2UXWA 1UDYA 3GQTA 4G97A 5J6AA 4E02A 3OWMA 1XFUA 1XFWA 2C12A 4L3XA 4MPNA 5J71A 3C46A 2VR0A 1U8VA 2C0UA 2PO4A 2XQRB 2Q8IA 1GJVA 4V25A 2A1TA 1SC5A 4QICA 3Q23A 4X28C 2IX6A 5K3HA 2VF1A 2FP2A 3KMLA 4X28A 5M4NA 4P13A 2YYMA 1GKZA 2LFWA 4AKGA 1UKWA 1QDBA 3MDEA 3AFFA 4Q5BA 2YYKA 2VIGA 2WBIA 3PFDA 3TZ4A 4KTOA 1EGDA 4XVXA 2Q8HA 2OEVA 1FS7A 3LG1A 4HKRA 3BNGA 1X91A 2CJ7A 2PG0A 5B5WA 4V26A 3VKGA 3NF4A 2ZDYA 3GNCA 1SIQA 1WS9A 4AKHA 4Q17A 3D9EA 2ZKJA 1GU6A 3MDDA 4MP7A 2D29A 2R0NA 2R02A 2Q8FA 2EC5A 5BRMA 1X90A 4ZXVA 3VKHA 3EONA 4H7QA 3C3LA 2EBAA 5M4KA 4O5MA 2BTZA 3Q0AA 3D9DA 4LQQB 2REHA 2R05A 3OIBA 2R03A 2EBHX 3LGQA 4L38A 2OJQA 2XS1A 1K93A 4NXLA 5K3JA 1XFZA 2JBTA 1JQIA 3MPJA 3EOMA 3OWAA 3SCEA 3BNJA 2ZAFA 1LVCA 3BNHA 2XS8A 1RP3A 3D2RA 3D6BA 4RM7A 4AI6A 4HKSA 5B5VA 1R2JA 4Q0TA 1S26A 2YYIA 3UBRA 4MPCA 3D9FA 1X8ZA 3GM6A 3SF6A 2CX9A 2E81A 3M9VA 3BNFA 4KCFA 2DVLA 2GBBA 4W9UA 4P79A 3II9A 1IS2A 2HJNA 1FS9A 4IRNA 4DZYA 4KSAA 4AKIA 2OR0A 1Y8OA 4DOYA 3C2PA 4U83A 2BU6A 3Q24A 1GKXA 3MXLA 5M4PA 3S7WA 3N0RA 4H81A 2OT4A 4Q4UA 2QR4A 2CJ6A 4Q1OA 2Q8GA 3RKHA 2R0MA 4FF4A 3X0XA 4E00A 5GJWE 1RJ1A 3P4TA 3D1IA 2BU8A 5M4MA 3D9GA 1EGCA 3MMOA 5GJVE 5K3GA 1SIRA 1IVHA 2F6LA 2YYJA 3F29A 1PK0A 1XFYA 2RFQA 2BU7A 3CRLA 3FO3A 3MPIA 4JIOA 4N5FA 4F0XA 2JBRA 4KSFA 1SK6A 1FS8A 2BU2A 2BU5A 2YYGA 3FCJA 4LQSB 3TTBA 3B96A 2JIFA 3L1TA 2FP1A 1BUCA 2RDZA 2YGWA 1W07A 2EBFX 3MKHA 4G5EA 4HR3A 4IV6A 4L1FA 2E80A 4L3YA 1OAHA 3UU9A 2PNRA 3SWOA 4MP2A 4Q5CA 5B6BA 3TORA 4KS9A 4MPEA 1EGEA 2CJ4A 2ZO5A 4J1VA 5K3IA 4FF2A 5BRKA 1XFXA 1PI1A 2FONA 2E0AA 1XFVA 4L3ZA 2ZDXA 4M9AA 4E01A 3TZ5A 2YYLA 3CRKA 3X29A 2CJ5A 2AO2A 2DDHA 1Y8PA 3SXQA 1T9GA
chains in the Genus database with same CATH topology
2AZEA 1PK0A 1XFYA 4F0XA 1LVCA 1RP3A 4HKRA 4FF1A 4KSFA 1SK6A 4AI6A 1S26A 1Y0VA 3Q22A 3CE2A 3VKGA 4FF3A 2FP1A 4AKHA 2YGWA 2EBFX 2GBBA 4HKSA 4FZ4A 4P79A 1K8TA 1K90A 4G97A 4KSAA 4AKIA 1XFUA 1XFWA 3C46A 2EC5A 3C2PA 3VKHA 2PO4A 4KS9A 3Q24A 3C3LA 3N0RA 3Q0AA 4FF2A 1SC5A 4QICA 1XFXA 2QR4A 3Q23A 4FF4A 1XFVA 2EBHX 2VF1A 5GJWE 2FP2A 3KMLA 3X29A 2AO2A 1K93A 2LFWA 5GJVE 1XFZA 4AKGA 2F6LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HKS A;  4HKR A; 
#chains in the Genus database with same CATH topology
 1Y8N A;  3R7K A;  1R3B A;  2AZE A;  1RX0 A;  4WJY A;  3X0Y A;  4FF1 A;  2CJ8 A;  2OEX A;  2RF7 A;  3TZ2 A;  2J7A A;  4JEK A;  1JM6 A;  1Y0V A;  3TZ0 A;  3Q22 A;  3CE2 A;  3VAD A;  4FF3 A;  4OO2 A;  4JIZ A;  2JBS A;  4ZYJ A;  4H85 A;  1XG2 B;  3HWC A;  1RJ4 A;  3AFE A;  2IX5 A;  4FZ4 A;  1K8T A;  2Z1Q A;  1K90 A;  2UXW A;  1UDY A;  3GQT A;  4G97 A;  5J6A A;  4E02 A;  3OWM A;  1XFU A;  1XFW A;  2C12 A;  4L3X A;  4MPN A;  5J71 A;  3C46 A;  2VR0 A;  1U8V A;  2C0U A;  2PO4 A;  2XQR B;  2Q8I A;  1GJV A;  4V25 A;  2A1T A;  1SC5 A;  4QIC A;  3Q23 A;  4X28 C;  2IX6 A;  5K3H A;  2VF1 A;  2FP2 A;  3KML A;  4X28 A;  5M4N A;  4P13 A;  2YYM A;  1GKZ A;  2LFW A;  4AKG A;  1UKW A;  1QDB A;  3MDE A;  3AFF A;  4Q5B A;  2YYK A;  2VIG A;  2WBI A;  3PFD A;  3TZ4 A;  4KTO A;  1EGD A;  4XVX A;  2Q8H A;  2OEV A;  1FS7 A;  3LG1 A;  4HKR A;  3BNG A;  1X91 A;  2CJ7 A;  2PG0 A;  5B5W A;  4V26 A;  3VKG A;  3NF4 A;  2ZDY A;  3GNC A;  1SIQ A;  1WS9 A;  4AKH A;  4Q17 A;  3D9E A;  2ZKJ A;  1GU6 A;  3MDD A;  4MP7 A;  2D29 A;  2R0N A;  2R02 A;  2Q8F A;  2EC5 A;  5BRM A;  1X90 A;  4ZXV A;  3VKH A;  3EON A;  4H7Q A;  3C3L A;  2EBA A;  5M4K A;  4O5M A;  2BTZ A;  3Q0A A;  3D9D A;  4LQQ B;  2REH A;  2R05 A;  3OIB A;  2R03 A;  2EBH X;  3LGQ A;  4L38 A;  2OJQ A;  2XS1 A;  1K93 A;  4NXL A;  5K3J A;  1XFZ A;  2JBT A;  1JQI A;  3MPJ A;  3EOM A;  3OWA A;  3SCE A;  3BNJ A;  2ZAF A;  1LVC A;  3BNH A;  2XS8 A;  1RP3 A;  3D2R A;  3D6B A;  4RM7 A;  4AI6 A;  4HKS A;  5B5V A;  1R2J A;  4Q0T A;  1S26 A;  2YYI A;  3UBR A;  4MPC A;  3D9F A;  1X8Z A;  3GM6 A;  3SF6 A;  2CX9 A;  2E81 A;  3M9V A;  3BNF A;  4KCF A;  2DVL A;  2GBB A;  4W9U A;  4P79 A;  3II9 A;  1IS2 A;  2HJN A;  1FS9 A;  4IRN A;  4DZY A;  4KSA A;  4AKI A;  2OR0 A;  1Y8O A;  4DOY A;  3C2P A;  4U83 A;  2BU6 A;  3Q24 A;  1GKX A;  3MXL A;  5M4P A;  3S7W A;  3N0R A;  4H81 A;  2OT4 A;  4Q4U A;  2QR4 A;  2CJ6 A;  4Q1O A;  2Q8G A;  3RKH A;  2R0M A;  4FF4 A;  3X0X A;  4E00 A;  5GJW E;  1RJ1 A;  3P4T A;  3D1I A;  2BU8 A;  5M4M A;  3D9G A;  1EGC A;  3MMO A;  5GJV E;  5K3G A;  1SIR A;  1IVH A;  2F6L A;  2YYJ A;  3F29 A;  1PK0 A;  1XFY A;  2RFQ A;  2BU7 A;  3CRL A;  3FO3 A;  3MPI A;  4JIO A;  4N5F A;  4F0X A;  2JBR A;  4KSF A;  1SK6 A;  1FS8 A;  2BU2 A;  2BU5 A;  2YYG A;  3FCJ A;  4LQS B;  3TTB A;  3B96 A;  2JIF A;  3L1T A;  2FP1 A;  1BUC A;  2RDZ A;  2YGW A;  1W07 A;  2EBF X;  3MKH A;  4G5E A;  4HR3 A;  4IV6 A;  4L1F A;  2E80 A;  4L3Y A;  1OAH A;  3UU9 A;  2PNR A;  3SWO A;  4MP2 A;  4Q5C A;  5B6B A;  3TOR A;  4KS9 A;  4MPE A;  1EGE A;  2CJ4 A;  2ZO5 A;  4J1V A;  5K3I A;  4FF2 A;  5BRK A;  1XFX A;  1PI1 A;  2FON A;  2E0A A;  1XFV A;  4L3Z A;  2ZDX A;  4M9A A;  4E01 A;  3TZ5 A;  2YYL A;  3CRK A;  3X29 A;  2CJ5 A;  2AO2 A;  2DDH A;  1Y8P A;  3SXQ A;  1T9G A; 
#chains in the Genus database with same CATH homology
 2AZE A;  1PK0 A;  1XFY A;  4F0X A;  1LVC A;  1RP3 A;  4HKR A;  4FF1 A;  4KSF A;  1SK6 A;  4AI6 A;  1S26 A;  1Y0V A;  3Q22 A;  3CE2 A;  3VKG A;  4FF3 A;  2FP1 A;  4AKH A;  2YGW A;  2EBF X;  2GBB A;  4HKS A;  4FZ4 A;  4P79 A;  1K8T A;  1K90 A;  4G97 A;  4KSA A;  4AKI A;  1XFU A;  1XFW A;  3C46 A;  2EC5 A;  3C2P A;  3VKH A;  2PO4 A;  4KS9 A;  3Q24 A;  3C3L A;  3N0R A;  3Q0A A;  4FF2 A;  1SC5 A;  4QIC A;  1XFX A;  2QR4 A;  3Q23 A;  4FF4 A;  1XFV A;  2EBH X;  2VF1 A;  5GJW E;  2FP2 A;  3KML A;  3X29 A;  2AO2 A;  1K93 A;  2LFW A;  5GJV E;  1XFZ A;  4AKG A;  2F6L A; 
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