3EOMA

2.4 a crystal structure of native glutaryl-coa dehydrogenase from burkholderia pseudomallei
Total Genus 148
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
148
sequence length
392
structure length
387
Chain Sequence
ATFHWDDPLLLDQQLADDERMVRDAAHAYAQGKLAPRVTEAFRHETTDAAIFREMGEIGLLGPTIPEQYGGPGLDYVSYGLIAREVERVDSGYRSMMSVQSSLVMVPIFEFGSDAQKEKYLPKLATGEWIGCFGLTEPDPGSMVTRARKVPGGYSLSGSKMWITNSPIADVFVVWAKLDEDGRDEIRGFILEKGCKGLSAPAIHGKVGLRASITGEIVLDEAFVPEENILPHVKGLRGPFTCLNSARYGIAWGALGAAESCWHIARQYVLDRKQFGRPLAANQLIQKKLADMQTEITLGLQGVLRLGRMKDEGTAAVEITSIMKRNSCGKALDIARLARDMLGGNGSDEFGVARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
molecule keywords Glutaryl-CoA dehydrogenase
publication title Probing conformational states of glutaryl-CoA dehydrogenase by fragment screening.
pubmed doi rcsb
source organism Burkholderia pseudomallei
total genus 148
structure length 387
sequence length 392
chains with identical sequence B, C, D
ec nomenclature ec 1.3.99.7: Transferred entry: 1.3.8.6.
pdb deposition date 2008-09-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 3eomA01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 3eomA03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 3eomA02
4L3YA 1UDYA 4M9AA 5K3IA 2IX6A 3D9FA 1WS9A 2C0UA 3MPIA 4ZYJA 4JEKA 4HR3A 4IRNA 3MPJA 1T9GA 3GQTA 2YYIA 4KTOA 2VIGA 4N5FA 2YYMA 4Q4UA 2RDZA 4P13A 3RKHA 3MDEA 3PFDA 2UXWA 3OWAA 5K3JA 3BNJA 4L3ZA 2CX9A 4WJYA 1R2JA 1QDBA 2VR0A 4X28A 2ZO5A 3SXQA 3UBRA 3X0YA 3SF6A 2WBIA 3UU9A 3D9DA 2J7AA 4NXLA 1SIRA 3D9EA 1OAHA 4L1FA 1IVHA 3EONA 3F29A 3HWCA 3OIBA 3R7KA 1IS2A 4X28C 3LG1A 3M9VA 1GU6A 4Q0TA 4Q5BA 4DOYA 4L3XA 4Q5CA 2PG0A 4Q17A 2DVLA 3AFFA 4Q1OA 3GM6A 1SIQA 3FCJA 4KCFA 1RX0A 2YYGA 2YYLA 3TTBA 2IX5A 2REHA 3BNGA 2EBAA 1FS7A 1EGDA 1JQIA 2E80A 3LGQA 3S7WA 3SWOA 2JBRA 3AFEA 3D6BA 3MXLA 4XVXA 3MDDA 4W9UA 5K3HA 3D1IA 3GNCA 4ZXVA 3BNFA 2R0MA 2YYJA 3SCEA 4L38A 2FONA 1EGCA 1W07A 2A1TA 4O5MA 4G5EA 3D9GA 2ZAFA 3EOMA 1FS9A 2JBTA 5K3GA 1U8VA 2D29A 4RM7A 2OR0A 3OWMA 2E81A 4OO2A 2RFQA 2C12A 2YYKA 3MKHA 2R0NA 2RF7A 2JIFA 2OT4A 3TORA 3FO3A 1FS8A 4U83A 1BUCA 3B96A 3NF4A 2Z1QA 1EGEA 3L1TA 3P4TA 3MMOA 3BNHA 2DDHA 2JBSA 1UKWA 3II9A 3X0XA 4IV6A
chains in the Genus database with same CATH superfamily
4G97A 4L3YA 1K90A 4OO2A 1UDYA 4M9AA 5K3IA 2IX6A 3D9FA 1WS9A 2C0UA 3MPIA 2CJ7A 2ZKJA 1SK6A 4ZYJA 2OEXA 3Q23A 4JEKA 1Y8PA 4HR3A 4IRNA 3MPJA 1T9GA 3GQTA 5BRMA 2YYIA 4KTOA 1XFXA 4KSAA 4MP2A 2VIGA 4N5FA 2YYMA 4Q4UA 5GJWE 2RDZA 2Q8FA 4AI6A 2BU7A 4P13A 2AO2A 3RKHA 3MDEA 3PFDA 2UXWA 3OWAA 5K3JA 3BNJA 2LFWA 2CX9A 1SC5A 4L3ZA 3C2PA 2E0AA 5M4KA 2XS1A 5B6BA 4KS9A 5BRKA 4FF2A 3D2RA 4WJYA 1R2JA 1QDBA 2VR0A 4X28A 2ZO5A 3SXQA 3UBRA 4H81A 3X0YA 2OEVA 3SF6A 2WBIA 3UU9A 3D9DA 1XFVA 2BU6A 2J7AA 4NXLA 4FF3A 3U33A 2R05A 4QICA 1SIRA 3D9EA 3Q24A 1OAHA 4DZYA 2GBBA 4L1FA 1IVHA 3EONA 1RJ1A 1XFYA 3F29A 3HWCA 1R3BA 3OIBA 3R7KA 1IS2A 3KMLA 1X8ZA 4MPEA 4X28C 3LG1A 3C46A 2EBHX 1XFWA 3M9VA 1GU6A 4JIZA 4Q5BA 4Q0TA 1RP3A 4DOYA 4L3XA 2CJ8A 2PG0A 4Q5CA 2DVLA 4Q17A 2Q8IA 3AFFA 5EZ3A 4Q1OA 4V25A 3GM6A 1XFUA 2CJ4A 1SIQA 3VADA 4AKIA 3FCJA 4KCFA 1RX0A 2OJQA 3TZ5A 2YYGA 4FF1A 2BU5A 2YYLA 4E01A 1K8TA 1JM6A 3TTBA 2IX5A 2REHA 2QR4A 1LVCA 2XS8A 3BNGA 2EBAA 1FS7A 3TZ2A 1EGDA 1JQIA 2BU8A 2E80A 4E00A 3LGQA 2ZDYA 3S7WA 3SWOA 2JBRA 3AFEA 3D6BA 2BTZA 4KSFA 3VKHA 3MXLA 4MPCA 2R02A 4XVXA 4MP7A 3MDDA 4W9UA 5K3HA 3D1IA 5B5WA 1XG2B 3GNCA 4ZXVA 1X91A 2R0MA 3BNFA 3Q0AA 2YYJA 2XQRB 3SCEA 1Y8NA 1XFZA 4L38A 4LQSB 3C3LA 5M4NA 3DJLA 2FONA 1EGCA 1W07A 2Q8HA 3N0RA 1Y0VA 2R03A 2A1TA 4O5MA 4G5EA 3D9GA 2F6LA 5B5VA 1X90A 1RJ4A 4HKSA 2ZAFA 2FP1A 3EOMA 1PK0A 1Y8OA 4AKGA 5M4MA 1FS9A 1GJVA 2JBTA 3X29A 5K3GA 2EBFX 1U8VA 3TZ4A 2VF1A 2D29A 2HJNA 2EC5A 4RM7A 2OR0A 1GKZA 2E81A 2FP2A 3OWMA 4FZ4A 2RFQA 2C12A 2YYKA 3CE2A 4JIOA 4V26A 2AZEA 3CRLA 3MKHA 2R0NA 2RF7A 4LQQB 2JIFA 2OT4A 3TORA 1GKXA 3FO3A 1FS8A 4P79A 4U83A 2Q8GA 3TZ0A 4H85A 4MPNA 4HKRA 4E02A 1BUCA 3B96A 3NF4A 2Z1QA 2CJ6A 5M4PA 3Q22A 1EGEA 1K93A 1PI1A 2BU2A 4F0XA 2ZDXA 5J6AA 5J71A 3L1TA 3P4TA 3MMOA 2PO4A 2YGWA 4FF4A 5GJVE 3BNHA 2DDHA 4H7QA 4AKHA 2JBSA 2PNRA 3CRKA 1UKWA 1S26A 3II9A 3VKGA 2CJ5A 3X0XA 4IV6A 4J1VA
chains in the Genus database with same CATH topology
4L3YA 1UDYA 4M9AA 5K3IA 2IX6A 3D9FA 1WS9A 2C0UA 3MPIA 4ZYJA 4JEKA 4HR3A 4IRNA 3MPJA 1T9GA 3GQTA 2YYIA 4KTOA 2VIGA 4N5FA 2YYMA 4Q4UA 2RDZA 4P13A 3RKHA 3MDEA 3PFDA 2UXWA 3OWAA 5K3JA 3BNJA 4L3ZA 2CX9A 4WJYA 1R2JA 1QDBA 2VR0A 4X28A 2ZO5A 3SXQA 3UBRA 3X0YA 3SF6A 2WBIA 3UU9A 3D9DA 2J7AA 4NXLA 1SIRA 3D9EA 1OAHA 4L1FA 1IVHA 3EONA 3F29A 3HWCA 3OIBA 3R7KA 1IS2A 4X28C 3LG1A 3M9VA 1GU6A 4Q0TA 4Q5BA 4DOYA 4L3XA 4Q5CA 2PG0A 4Q17A 2DVLA 3AFFA 4Q1OA 3GM6A 1SIQA 3FCJA 4KCFA 1RX0A 2YYGA 2YYLA 3TTBA 2IX5A 2REHA 3BNGA 2EBAA 1FS7A 1EGDA 1JQIA 2E80A 3LGQA 3S7WA 3SWOA 2JBRA 3AFEA 3D6BA 3MXLA 4XVXA 3MDDA 4W9UA 5K3HA 3D1IA 3GNCA 4ZXVA 3BNFA 2R0MA 2YYJA 3SCEA 4L38A 2FONA 1EGCA 1W07A 2A1TA 4O5MA 4G5EA 3D9GA 2ZAFA 3EOMA 1FS9A 2JBTA 5K3GA 1U8VA 2D29A 4RM7A 2OR0A 3OWMA 2E81A 4OO2A 2RFQA 2C12A 2YYKA 3MKHA 2R0NA 2RF7A 2JIFA 2OT4A 3TORA 3FO3A 1FS8A 4U83A 1BUCA 3B96A 3NF4A 2Z1QA 1EGEA 3L1TA 3P4TA 3MMOA 3BNHA 2DDHA 2JBSA 1UKWA 3II9A 3X0XA 4IV6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L3Y A;  1UDY A;  4M9A A;  5K3I A;  2IX6 A;  3D9F A;  1WS9 A;  2C0U A;  3MPI A;  4ZYJ A;  4JEK A;  4HR3 A;  4IRN A;  3MPJ A;  1T9G A;  3GQT A;  2YYI A;  4KTO A;  2VIG A;  4N5F A;  2YYM A;  4Q4U A;  2RDZ A;  4P13 A;  3RKH A;  3MDE A;  3PFD A;  2UXW A;  3OWA A;  5K3J A;  3BNJ A;  4L3Z A;  2CX9 A;  4WJY A;  1R2J A;  1QDB A;  2VR0 A;  4X28 A;  2ZO5 A;  3SXQ A;  3UBR A;  3X0Y A;  3SF6 A;  2WBI A;  3UU9 A;  3D9D A;  2J7A A;  4NXL A;  1SIR A;  3D9E A;  1OAH A;  4L1F A;  1IVH A;  3EON A;  3F29 A;  3HWC A;  3OIB A;  3R7K A;  1IS2 A;  4X28 C;  3LG1 A;  3M9V A;  1GU6 A;  4Q0T A;  4Q5B A;  4DOY A;  4L3X A;  4Q5C A;  2PG0 A;  4Q17 A;  2DVL A;  3AFF A;  4Q1O A;  3GM6 A;  1SIQ A;  3FCJ A;  4KCF A;  1RX0 A;  2YYG A;  2YYL A;  3TTB A;  2IX5 A;  2REH A;  3BNG A;  2EBA A;  1FS7 A;  1EGD A;  1JQI A;  2E80 A;  3LGQ A;  3S7W A;  3SWO A;  2JBR A;  3AFE A;  3D6B A;  3MXL A;  4XVX A;  3MDD A;  4W9U A;  5K3H A;  3D1I A;  3GNC A;  4ZXV A;  3BNF A;  2R0M A;  2YYJ A;  3SCE A;  4L38 A;  2FON A;  1EGC A;  1W07 A;  2A1T A;  4O5M A;  4G5E A;  3D9G A;  2ZAF A;  3EOM A;  1FS9 A;  2JBT A;  5K3G A;  1U8V A;  2D29 A;  4RM7 A;  2OR0 A;  3OWM A;  2E81 A;  4OO2 A;  2RFQ A;  2C12 A;  2YYK A;  3MKH A;  2R0N A;  2RF7 A;  2JIF A;  2OT4 A;  3TOR A;  3FO3 A;  1FS8 A;  4U83 A;  1BUC A;  3B96 A;  3NF4 A;  2Z1Q A;  1EGE A;  3L1T A;  3P4T A;  3MMO A;  3BNH A;  2DDH A;  2JBS A;  1UKW A;  3II9 A;  3X0X A;  4IV6 A; 
#chains in the Genus database with same CATH topology
 4G97 A;  4L3Y A;  1K90 A;  4OO2 A;  1UDY A;  4M9A A;  5K3I A;  2IX6 A;  3D9F A;  1WS9 A;  2C0U A;  3MPI A;  2CJ7 A;  2ZKJ A;  1SK6 A;  4ZYJ A;  2OEX A;  3Q23 A;  4JEK A;  1Y8P A;  4HR3 A;  4IRN A;  3MPJ A;  1T9G A;  3GQT A;  5BRM A;  2YYI A;  4KTO A;  1XFX A;  4KSA A;  4MP2 A;  2VIG A;  4N5F A;  2YYM A;  4Q4U A;  5GJW E;  2RDZ A;  2Q8F A;  4AI6 A;  2BU7 A;  4P13 A;  2AO2 A;  3RKH A;  3MDE A;  3PFD A;  2UXW A;  3OWA A;  5K3J A;  3BNJ A;  2LFW A;  2CX9 A;  1SC5 A;  4L3Z A;  3C2P A;  2E0A A;  5M4K A;  2XS1 A;  5B6B A;  4KS9 A;  5BRK A;  4FF2 A;  3D2R A;  4WJY A;  1R2J A;  1QDB A;  2VR0 A;  4X28 A;  2ZO5 A;  3SXQ A;  3UBR A;  4H81 A;  3X0Y A;  2OEV A;  3SF6 A;  2WBI A;  3UU9 A;  3D9D A;  1XFV A;  2BU6 A;  2J7A A;  4NXL A;  4FF3 A;  3U33 A;  2R05 A;  4QIC A;  1SIR A;  3D9E A;  3Q24 A;  1OAH A;  4DZY A;  2GBB A;  4L1F A;  1IVH A;  3EON A;  1RJ1 A;  1XFY A;  3F29 A;  3HWC A;  1R3B A;  3OIB A;  3R7K A;  1IS2 A;  3KML A;  1X8Z A;  4MPE A;  4X28 C;  3LG1 A;  3C46 A;  2EBH X;  1XFW A;  3M9V A;  1GU6 A;  4JIZ A;  4Q5B A;  4Q0T A;  1RP3 A;  4DOY A;  4L3X A;  2CJ8 A;  2PG0 A;  4Q5C A;  2DVL A;  4Q17 A;  2Q8I A;  3AFF A;  5EZ3 A;  4Q1O A;  4V25 A;  3GM6 A;  1XFU A;  2CJ4 A;  1SIQ A;  3VAD A;  4AKI A;  3FCJ A;  4KCF A;  1RX0 A;  2OJQ A;  3TZ5 A;  2YYG A;  4FF1 A;  2BU5 A;  2YYL A;  4E01 A;  1K8T A;  1JM6 A;  3TTB A;  2IX5 A;  2REH A;  2QR4 A;  1LVC A;  2XS8 A;  3BNG A;  2EBA A;  1FS7 A;  3TZ2 A;  1EGD A;  1JQI A;  2BU8 A;  2E80 A;  4E00 A;  3LGQ A;  2ZDY A;  3S7W A;  3SWO A;  2JBR A;  3AFE A;  3D6B A;  2BTZ A;  4KSF A;  3VKH A;  3MXL A;  4MPC A;  2R02 A;  4XVX A;  4MP7 A;  3MDD A;  4W9U A;  5K3H A;  3D1I A;  5B5W A;  1XG2 B;  3GNC A;  4ZXV A;  1X91 A;  2R0M A;  3BNF A;  3Q0A A;  2YYJ A;  2XQR B;  3SCE A;  1Y8N A;  1XFZ A;  4L38 A;  4LQS B;  3C3L A;  5M4N A;  3DJL A;  2FON A;  1EGC A;  1W07 A;  2Q8H A;  3N0R A;  1Y0V A;  2R03 A;  2A1T A;  4O5M A;  4G5E A;  3D9G A;  2F6L A;  5B5V A;  1X90 A;  1RJ4 A;  4HKS A;  2ZAF A;  2FP1 A;  3EOM A;  1PK0 A;  1Y8O A;  4AKG A;  5M4M A;  1FS9 A;  1GJV A;  2JBT A;  3X29 A;  5K3G A;  2EBF X;  1U8V A;  3TZ4 A;  2VF1 A;  2D29 A;  2HJN A;  2EC5 A;  4RM7 A;  2OR0 A;  1GKZ A;  2E81 A;  2FP2 A;  3OWM A;  4FZ4 A;  2RFQ A;  2C12 A;  2YYK A;  3CE2 A;  4JIO A;  4V26 A;  2AZE A;  3CRL A;  3MKH A;  2R0N A;  2RF7 A;  4LQQ B;  2JIF A;  2OT4 A;  3TOR A;  1GKX A;  3FO3 A;  1FS8 A;  4P79 A;  4U83 A;  2Q8G A;  3TZ0 A;  4H85 A;  4MPN A;  4HKR A;  4E02 A;  1BUC A;  3B96 A;  3NF4 A;  2Z1Q A;  2CJ6 A;  5M4P A;  3Q22 A;  1EGE A;  1K93 A;  1PI1 A;  2BU2 A;  4F0X A;  2ZDX A;  5J6A A;  5J71 A;  3L1T A;  3P4T A;  3MMO A;  2PO4 A;  2YGW A;  4FF4 A;  5GJV E;  3BNH A;  2DDH A;  4H7Q A;  4AKH A;  2JBS A;  2PNR A;  3CRK A;  1UKW A;  1S26 A;  3II9 A;  3VKG A;  2CJ5 A;  3X0X A;  4IV6 A;  4J1V A; 
#chains in the Genus database with same CATH homology
 4L3Y A;  1UDY A;  4M9A A;  5K3I A;  2IX6 A;  3D9F A;  1WS9 A;  2C0U A;  3MPI A;  4ZYJ A;  4JEK A;  4HR3 A;  4IRN A;  3MPJ A;  1T9G A;  3GQT A;  2YYI A;  4KTO A;  2VIG A;  4N5F A;  2YYM A;  4Q4U A;  2RDZ A;  4P13 A;  3RKH A;  3MDE A;  3PFD A;  2UXW A;  3OWA A;  5K3J A;  3BNJ A;  4L3Z A;  2CX9 A;  4WJY A;  1R2J A;  1QDB A;  2VR0 A;  4X28 A;  2ZO5 A;  3SXQ A;  3UBR A;  3X0Y A;  3SF6 A;  2WBI A;  3UU9 A;  3D9D A;  2J7A A;  4NXL A;  1SIR A;  3D9E A;  1OAH A;  4L1F A;  1IVH A;  3EON A;  3F29 A;  3HWC A;  3OIB A;  3R7K A;  1IS2 A;  4X28 C;  3LG1 A;  3M9V A;  1GU6 A;  4Q0T A;  4Q5B A;  4DOY A;  4L3X A;  4Q5C A;  2PG0 A;  4Q17 A;  2DVL A;  3AFF A;  4Q1O A;  3GM6 A;  1SIQ A;  3FCJ A;  4KCF A;  1RX0 A;  2YYG A;  2YYL A;  3TTB A;  2IX5 A;  2REH A;  3BNG A;  2EBA A;  1FS7 A;  1EGD A;  1JQI A;  2E80 A;  3LGQ A;  3S7W A;  3SWO A;  2JBR A;  3AFE A;  3D6B A;  3MXL A;  4XVX A;  3MDD A;  4W9U A;  5K3H A;  3D1I A;  3GNC A;  4ZXV A;  3BNF A;  2R0M A;  2YYJ A;  3SCE A;  4L38 A;  2FON A;  1EGC A;  1W07 A;  2A1T A;  4O5M A;  4G5E A;  3D9G A;  2ZAF A;  3EOM A;  1FS9 A;  2JBT A;  5K3G A;  1U8V A;  2D29 A;  4RM7 A;  2OR0 A;  3OWM A;  2E81 A;  4OO2 A;  2RFQ A;  2C12 A;  2YYK A;  3MKH A;  2R0N A;  2RF7 A;  2JIF A;  2OT4 A;  3TOR A;  3FO3 A;  1FS8 A;  4U83 A;  1BUC A;  3B96 A;  3NF4 A;  2Z1Q A;  1EGE A;  3L1T A;  3P4T A;  3MMO A;  3BNH A;  2DDH A;  2JBS A;  1UKW A;  3II9 A;  3X0X A;  4IV6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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