3NF4A

Crystal structure of acyl-coa dehydrogenase from mycobacterium thermoresistibile bound to flavin adenine dinucleotide
Total Genus 127
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
127
sequence length
378
structure length
369
Chain Sequence
MAVDRLLPSQEAAELIELTREIADKVLDPIVDRHEKDETYPEGVFEQLGAAGLLSLPQPEEWGGGGQPYEVYLQVLEEIAARWASVAVAVSVHSLSSHPLLVFGTEEQKKRWLPGMLSGEQIGAYSLSEPQAGSDAAALRCAATPTDGGYVINGSKSWITHGGKADFYTLFARTGSRGVSCFLVPADQPGLSFGKPEEKMGLHAVPTTSAFYDNARIDADRRIGEEGQGLQIAFSALDSGRLGIAAVATGLAQAALDEAVAYANEKIIDHGLGFLLADMAAAVATARATYLDAARRRDQGRPYSQQASIAKLTATDAAMKVTTDAVQVFGGVGYTRDYRVERYMREAKIMQIFEGTNQIQRLVIARGLT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords acyl-CoA dehydrogenase
publication title Increasing the structural coverage of tuberculosis drug targets.
pubmed doi rcsb
source organism Mycobacterium thermoresistibile
molecule tags Oxidoreductase
total genus 127
structure length 369
sequence length 378
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-06-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 3nf4A01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 3nf4A03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 3nf4A02
3MPIA 1U8VA 3OWMA 3MDEA 3D6BA 1IVHA 1SIQA 1W07A 4OO2A 2ZO5A 2Z1QA 4L1FA 3S7WA 3TTBA 4L38A 2YYLA 3M9VA 5K3JA 4Q5BA 4JEKA 3SXQA 2JBSA 1JQIA 1BUCA 2VIGA 2VR0A 5K3GA 1RX0A 3TORA 3OIBA 4DOYA 4Q4UA 2OT4A 3EONA 5K3HA 3NF4A 2R0NA 3D9EA 2YYGA 2JIFA 3OWAA 1EGDA 3II9A 1OAHA 4WJYA 1R2JA 4W9UA 2EBAA 3SCEA 2ZAFA 4L3YA 2YYKA 2DVLA 1SIRA 2JBTA 3MXLA 4G5EA 3MPJA 4Q5CA 1EGCA 2IX5A 3AFFA 3BNFA 2RDZA 4IRNA 3D9FA 4O5MA 2C0UA 2UXWA 3D9GA 3MMOA 3F29A 4ZXVA 3SWOA 4U83A 1EGEA 3D9DA 3LGQA 2JBRA 4Q1OA 4NXLA 3GQTA 1UDYA 3X0XA 1UKWA 4N5FA 3GNCA 1GU6A 2WBIA 4M9AA 2YYJA 4IV6A 1WS9A 2E81A 2E80A 3FCJA 4KTOA 2J7AA 3AFEA 2A1TA 3BNJA 1FS7A 2FONA 3EOMA 1FS9A 3P4TA 2IX6A 2PG0A 3MKHA 4ZYJA 3FO3A 2REHA 3R7KA 4XVXA 2OR0A 3MDDA 4Q0TA 4Q17A 4KCFA 4X28A 3UU9A 3LG1A 3B96A 2RF7A 1T9GA 2C12A 3HWCA 4L3XA 1FS8A 2D29A 2CX9A 4L3ZA 3SF6A 5K3IA 1IS2A 2DDHA 3D1IA 3GM6A 3L1TA 3X0YA 3RKHA 2YYIA 3UBRA 1QDBA 3BNHA 2RFQA 4RM7A 2R0MA 2YYMA 3PFDA 4X28C 3BNGA 4HR3A 4P13A
chains in the Genus database with same CATH superfamily
2Q8FA 3MPIA 1U8VA 3OWMA 4H7QA 3MDEA 3D6BA 1IVHA 1X91A 4FF1A 4FF2A 1S26A 3C2PA 1SIQA 4G97A 1W07A 4OO2A 2Q8HA 2ZO5A 3N0RA 2Z1QA 1K8TA 4L1FA 2FP1A 1PK0A 2XS1A 3S7WA 3TTBA 4L38A 2YYLA 3M9VA 2CJ4A 4AKHA 5K3JA 4Q5BA 4JEKA 5M4KA 3SXQA 4MPCA 3TZ2A 1RJ4A 2JBSA 2CJ8A 2ZKJA 2Q8IA 1JQIA 3VKHA 1BUCA 3VADA 2R05A 5M4PA 2VIGA 2VR0A 5K3GA 2LFWA 1RX0A 4AI6A 3TORA 3OIBA 4DOYA 1RJ1A 2PO4A 2YGWA 4Q4UA 2Q8GA 2OT4A 3EONA 1XFUA 5K3HA 2CJ6A 2E0AA 4MPNA 4E01A 2CJ5A 1R3BA 3NF4A 1XFVA 2R0NA 3D9EA 2YYGA 2JIFA 5BRMA 3CRLA 3OWAA 1EGDA 2BU8A 3II9A 1OAHA 2R02A 2R03A 3CE2A 5B5VA 1XFYA 2GBBA 4WJYA 3CRKA 4H81A 1R2JA 4W9UA 4LQSB 2EBAA 4LQQB 3SCEA 2OEXA 1K93A 2ZAFA 4L3YA 2YYKA 2DVLA 1SIRA 2BU7A 1RP3A 5GJWE 4FZ4A 2JBTA 3MXLA 4G5EA 3MPJA 2AO2A 1EGCA 2ZDXA 4KSAA 4Q5CA 2IX5A 3AFFA 3BNFA 2RDZA 4IRNA 3Q24A 3D9FA 4O5MA 4FF3A 3Q0AA 2C0UA 2UXWA 3D9GA 3MMOA 1GKXA 4KS9A 3F29A 4ZXVA 5GJVE 3SWOA 1X8ZA 4JIZA 5BRKA 4U83A 1Y8NA 1EGEA 3D9DA 3LGQA 2JBRA 4Q1OA 4AKGA 4NXLA 1XFZA 3GQTA 1UDYA 3X0XA 1UKWA 4N5FA 2F6LA 4H85A 5M4MA 2HJNA 4FF4A 3GNCA 1Y8OA 1GU6A 2WBIA 4M9AA 2YYJA 4KSFA 3Q22A 4E02A 4IV6A 1WS9A 4E00A 2E81A 2E80A 3FCJA 2PNRA 4KTOA 2J7AA 1X90A 4MP2A 3AFEA 4AKIA 3VKGA 2OEVA 2A1TA 3BNJA 3C46A 1K90A 1FS7A 2FONA 1XG2B 5B6BA 3EOMA 2XQRB 1XFXA 2EBHX 1FS9A 3P4TA 2EBFX 2IX6A 2PG0A 2QR4A 3MKHA 2BU6A 4ZYJA 5J6AA 3FO3A 2REHA 3R7KA 4XVXA 2OR0A 4F0XA 3MDDA 3Q23A 1LVCA 4J1VA 4Q0TA 4MP7A 4Q17A 4V25A 4KCFA 4MPEA 4JIOA 2AZEA 4X28A 3TZ4A 1SC5A 3UU9A 3LG1A 3B96A 1Y0VA 2RF7A 1T9GA 2C12A 3D2RA 2VF1A 1FS8A 1GJVA 3HWCA 3KMLA 4HKSA 4P79A 1Y8PA 5J71A 4QICA 1XFWA 2XS8A 3DJLA 2D29A 1SK6A 2FP2A 3TZ5A 5EZ3A 2CX9A 1PI1A 2ZDYA 5M4NA 3X29A 4L3ZA 4V26A 2OJQA 2CJ7A 2EC5A 3SF6A 1JM6A 5K3IA 1IS2A 2DDHA 5B5WA 1GKZA 3D1IA 3GM6A 3L1TA 3X0YA 3RKHA 2YYIA 3UBRA 4DZYA 1QDBA 2BTZA 4L3XA 3BNHA 3C3LA 3TZ0A 2RFQA 4RM7A 2BU5A 2R0MA 2YYMA 4HKRA 3PFDA 3U33A 4X28C 2BU2A 3BNGA 4HR3A 4P13A
chains in the Genus database with same CATH topology
3MPIA 1U8VA 3OWMA 3MDEA 3D6BA 1IVHA 1SIQA 1W07A 4OO2A 2ZO5A 2Z1QA 4L1FA 3S7WA 3TTBA 4L38A 2YYLA 3M9VA 5K3JA 4Q5BA 4JEKA 3SXQA 2JBSA 1JQIA 1BUCA 2VIGA 2VR0A 5K3GA 1RX0A 3TORA 3OIBA 4DOYA 4Q4UA 2OT4A 3EONA 5K3HA 3NF4A 2R0NA 3D9EA 2YYGA 2JIFA 3OWAA 1EGDA 3II9A 1OAHA 4WJYA 1R2JA 4W9UA 2EBAA 3SCEA 2ZAFA 4L3YA 2YYKA 2DVLA 1SIRA 2JBTA 3MXLA 4G5EA 3MPJA 4Q5CA 1EGCA 2IX5A 3AFFA 3BNFA 2RDZA 4IRNA 3D9FA 4O5MA 2C0UA 2UXWA 3D9GA 3MMOA 3F29A 4ZXVA 3SWOA 4U83A 1EGEA 3D9DA 3LGQA 2JBRA 4Q1OA 4NXLA 3GQTA 1UDYA 3X0XA 1UKWA 4N5FA 3GNCA 1GU6A 2WBIA 4M9AA 2YYJA 4IV6A 1WS9A 2E81A 2E80A 3FCJA 4KTOA 2J7AA 3AFEA 2A1TA 3BNJA 1FS7A 2FONA 3EOMA 1FS9A 3P4TA 2IX6A 2PG0A 3MKHA 4ZYJA 3FO3A 2REHA 3R7KA 4XVXA 2OR0A 3MDDA 4Q0TA 4Q17A 4KCFA 4X28A 3UU9A 3LG1A 3B96A 2RF7A 1T9GA 2C12A 3HWCA 4L3XA 1FS8A 2D29A 2CX9A 4L3ZA 3SF6A 5K3IA 1IS2A 2DDHA 3D1IA 3GM6A 3L1TA 3X0YA 3RKHA 2YYIA 3UBRA 1QDBA 3BNHA 2RFQA 4RM7A 2R0MA 2YYMA 3PFDA 4X28C 3BNGA 4HR3A 4P13A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MPI A;  1U8V A;  3OWM A;  3MDE A;  3D6B A;  1IVH A;  1SIQ A;  1W07 A;  4OO2 A;  2ZO5 A;  2Z1Q A;  4L1F A;  3S7W A;  3TTB A;  4L38 A;  2YYL A;  3M9V A;  5K3J A;  4Q5B A;  4JEK A;  3SXQ A;  2JBS A;  1JQI A;  1BUC A;  2VIG A;  2VR0 A;  5K3G A;  1RX0 A;  3TOR A;  3OIB A;  4DOY A;  4Q4U A;  2OT4 A;  3EON A;  5K3H A;  3NF4 A;  2R0N A;  3D9E A;  2YYG A;  2JIF A;  3OWA A;  1EGD A;  3II9 A;  1OAH A;  4WJY A;  1R2J A;  4W9U A;  2EBA A;  3SCE A;  2ZAF A;  4L3Y A;  2YYK A;  2DVL A;  1SIR A;  2JBT A;  3MXL A;  4G5E A;  3MPJ A;  4Q5C A;  1EGC A;  2IX5 A;  3AFF A;  3BNF A;  2RDZ A;  4IRN A;  3D9F A;  4O5M A;  2C0U A;  2UXW A;  3D9G A;  3MMO A;  3F29 A;  4ZXV A;  3SWO A;  4U83 A;  1EGE A;  3D9D A;  3LGQ A;  2JBR A;  4Q1O A;  4NXL A;  3GQT A;  1UDY A;  3X0X A;  1UKW A;  4N5F A;  3GNC A;  1GU6 A;  2WBI A;  4M9A A;  2YYJ A;  4IV6 A;  1WS9 A;  2E81 A;  2E80 A;  3FCJ A;  4KTO A;  2J7A A;  3AFE A;  2A1T A;  3BNJ A;  1FS7 A;  2FON A;  3EOM A;  1FS9 A;  3P4T A;  2IX6 A;  2PG0 A;  3MKH A;  4ZYJ A;  3FO3 A;  2REH A;  3R7K A;  4XVX A;  2OR0 A;  3MDD A;  4Q0T A;  4Q17 A;  4KCF A;  4X28 A;  3UU9 A;  3LG1 A;  3B96 A;  2RF7 A;  1T9G A;  2C12 A;  3HWC A;  4L3X A;  1FS8 A;  2D29 A;  2CX9 A;  4L3Z A;  3SF6 A;  5K3I A;  1IS2 A;  2DDH A;  3D1I A;  3GM6 A;  3L1T A;  3X0Y A;  3RKH A;  2YYI A;  3UBR A;  1QDB A;  3BNH A;  2RFQ A;  4RM7 A;  2R0M A;  2YYM A;  3PFD A;  4X28 C;  3BNG A;  4HR3 A;  4P13 A; 
#chains in the Genus database with same CATH topology
 2Q8F A;  3MPI A;  1U8V A;  3OWM A;  4H7Q A;  3MDE A;  3D6B A;  1IVH A;  1X91 A;  4FF1 A;  4FF2 A;  1S26 A;  3C2P A;  1SIQ A;  4G97 A;  1W07 A;  4OO2 A;  2Q8H A;  2ZO5 A;  3N0R A;  2Z1Q A;  1K8T A;  4L1F A;  2FP1 A;  1PK0 A;  2XS1 A;  3S7W A;  3TTB A;  4L38 A;  2YYL A;  3M9V A;  2CJ4 A;  4AKH A;  5K3J A;  4Q5B A;  4JEK A;  5M4K A;  3SXQ A;  4MPC A;  3TZ2 A;  1RJ4 A;  2JBS A;  2CJ8 A;  2ZKJ A;  2Q8I A;  1JQI A;  3VKH A;  1BUC A;  3VAD A;  2R05 A;  5M4P A;  2VIG A;  2VR0 A;  5K3G A;  2LFW A;  1RX0 A;  4AI6 A;  3TOR A;  3OIB A;  4DOY A;  1RJ1 A;  2PO4 A;  2YGW A;  4Q4U A;  2Q8G A;  2OT4 A;  3EON A;  1XFU A;  5K3H A;  2CJ6 A;  2E0A A;  4MPN A;  4E01 A;  2CJ5 A;  1R3B A;  3NF4 A;  1XFV A;  2R0N A;  3D9E A;  2YYG A;  2JIF A;  5BRM A;  3CRL A;  3OWA A;  1EGD A;  2BU8 A;  3II9 A;  1OAH A;  2R02 A;  2R03 A;  3CE2 A;  5B5V A;  1XFY A;  2GBB A;  4WJY A;  3CRK A;  4H81 A;  1R2J A;  4W9U A;  4LQS B;  2EBA A;  4LQQ B;  3SCE A;  2OEX A;  1K93 A;  2ZAF A;  4L3Y A;  2YYK A;  2DVL A;  1SIR A;  2BU7 A;  1RP3 A;  5GJW E;  4FZ4 A;  2JBT A;  3MXL A;  4G5E A;  3MPJ A;  2AO2 A;  1EGC A;  2ZDX A;  4KSA A;  4Q5C A;  2IX5 A;  3AFF A;  3BNF A;  2RDZ A;  4IRN A;  3Q24 A;  3D9F A;  4O5M A;  4FF3 A;  3Q0A A;  2C0U A;  2UXW A;  3D9G A;  3MMO A;  1GKX A;  4KS9 A;  3F29 A;  4ZXV A;  5GJV E;  3SWO A;  1X8Z A;  4JIZ A;  5BRK A;  4U83 A;  1Y8N A;  1EGE A;  3D9D A;  3LGQ A;  2JBR A;  4Q1O A;  4AKG A;  4NXL A;  1XFZ A;  3GQT A;  1UDY A;  3X0X A;  1UKW A;  4N5F A;  2F6L A;  4H85 A;  5M4M A;  2HJN A;  4FF4 A;  3GNC A;  1Y8O A;  1GU6 A;  2WBI A;  4M9A A;  2YYJ A;  4KSF A;  3Q22 A;  4E02 A;  4IV6 A;  1WS9 A;  4E00 A;  2E81 A;  2E80 A;  3FCJ A;  2PNR A;  4KTO A;  2J7A A;  1X90 A;  4MP2 A;  3AFE A;  4AKI A;  3VKG A;  2OEV A;  2A1T A;  3BNJ A;  3C46 A;  1K90 A;  1FS7 A;  2FON A;  1XG2 B;  5B6B A;  3EOM A;  2XQR B;  1XFX A;  2EBH X;  1FS9 A;  3P4T A;  2EBF X;  2IX6 A;  2PG0 A;  2QR4 A;  3MKH A;  2BU6 A;  4ZYJ A;  5J6A A;  3FO3 A;  2REH A;  3R7K A;  4XVX A;  2OR0 A;  4F0X A;  3MDD A;  3Q23 A;  1LVC A;  4J1V A;  4Q0T A;  4MP7 A;  4Q17 A;  4V25 A;  4KCF A;  4MPE A;  4JIO A;  2AZE A;  4X28 A;  3TZ4 A;  1SC5 A;  3UU9 A;  3LG1 A;  3B96 A;  1Y0V A;  2RF7 A;  1T9G A;  2C12 A;  3D2R A;  2VF1 A;  1FS8 A;  1GJV A;  3HWC A;  3KML A;  4HKS A;  4P79 A;  1Y8P A;  5J71 A;  4QIC A;  1XFW A;  2XS8 A;  3DJL A;  2D29 A;  1SK6 A;  2FP2 A;  3TZ5 A;  5EZ3 A;  2CX9 A;  1PI1 A;  2ZDY A;  5M4N A;  3X29 A;  4L3Z A;  4V26 A;  2OJQ A;  2CJ7 A;  2EC5 A;  3SF6 A;  1JM6 A;  5K3I A;  1IS2 A;  2DDH A;  5B5W A;  1GKZ A;  3D1I A;  3GM6 A;  3L1T A;  3X0Y A;  3RKH A;  2YYI A;  3UBR A;  4DZY A;  1QDB A;  2BTZ A;  4L3X A;  3BNH A;  3C3L A;  3TZ0 A;  2RFQ A;  4RM7 A;  2BU5 A;  2R0M A;  2YYM A;  4HKR A;  3PFD A;  3U33 A;  4X28 C;  2BU2 A;  3BNG A;  4HR3 A;  4P13 A; 
#chains in the Genus database with same CATH homology
 3MPI A;  1U8V A;  3OWM A;  3MDE A;  3D6B A;  1IVH A;  1SIQ A;  1W07 A;  4OO2 A;  2ZO5 A;  2Z1Q A;  4L1F A;  3S7W A;  3TTB A;  4L38 A;  2YYL A;  3M9V A;  5K3J A;  4Q5B A;  4JEK A;  3SXQ A;  2JBS A;  1JQI A;  1BUC A;  2VIG A;  2VR0 A;  5K3G A;  1RX0 A;  3TOR A;  3OIB A;  4DOY A;  4Q4U A;  2OT4 A;  3EON A;  5K3H A;  3NF4 A;  2R0N A;  3D9E A;  2YYG A;  2JIF A;  3OWA A;  1EGD A;  3II9 A;  1OAH A;  4WJY A;  1R2J A;  4W9U A;  2EBA A;  3SCE A;  2ZAF A;  4L3Y A;  2YYK A;  2DVL A;  1SIR A;  2JBT A;  3MXL A;  4G5E A;  3MPJ A;  4Q5C A;  1EGC A;  2IX5 A;  3AFF A;  3BNF A;  2RDZ A;  4IRN A;  3D9F A;  4O5M A;  2C0U A;  2UXW A;  3D9G A;  3MMO A;  3F29 A;  4ZXV A;  3SWO A;  4U83 A;  1EGE A;  3D9D A;  3LGQ A;  2JBR A;  4Q1O A;  4NXL A;  3GQT A;  1UDY A;  3X0X A;  1UKW A;  4N5F A;  3GNC A;  1GU6 A;  2WBI A;  4M9A A;  2YYJ A;  4IV6 A;  1WS9 A;  2E81 A;  2E80 A;  3FCJ A;  4KTO A;  2J7A A;  3AFE A;  2A1T A;  3BNJ A;  1FS7 A;  2FON A;  3EOM A;  1FS9 A;  3P4T A;  2IX6 A;  2PG0 A;  3MKH A;  4ZYJ A;  3FO3 A;  2REH A;  3R7K A;  4XVX A;  2OR0 A;  3MDD A;  4Q0T A;  4Q17 A;  4KCF A;  4X28 A;  3UU9 A;  3LG1 A;  3B96 A;  2RF7 A;  1T9G A;  2C12 A;  3HWC A;  4L3X A;  1FS8 A;  2D29 A;  2CX9 A;  4L3Z A;  3SF6 A;  5K3I A;  1IS2 A;  2DDH A;  3D1I A;  3GM6 A;  3L1T A;  3X0Y A;  3RKH A;  2YYI A;  3UBR A;  1QDB A;  3BNH A;  2RFQ A;  4RM7 A;  2R0M A;  2YYM A;  3PFD A;  4X28 C;  3BNG A;  4HR3 A;  4P13 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...