2YYIA

Crystal structure of the oxygenase component (hpab) of 4-hydroxyphenylacetate 3-monooxygenase complexed with fad
Total Genus 181
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
181
sequence length
476
structure length
474
Chain Sequence
ARTGAEYIEALKTRPPNLWYKGEKVEDPTTHPVFRGIVRTMAALYDLQHDPRYREVLTYEEEGKRHGMSFLIPKTKEDLKRRGQAYKLWADQNLGMMGRSPDYLNAVVMAYAASADYFGEFAENVRNYYRYLRDQDLATTHALTNPQVNRARPPSGQPDPYIPVGVVKQTEKGIVVRGARMTATFPLADEVLIFPLLQAGSEKYALAFALPTSTPGLHFVCREALVGGDSPFDHPLSSRVEEMDCLVIFDDVLVPWERVFILGNVELCNNAYAATGALNHMAHQVVALKTAKTEAFLGVAALMAEGIGADVYGHVQEKIAEIIVYLEAMRAFWTRAEEEAKENAYGLLVPDRGALDGARNLYPRLYPRIREILEQIGASGLITLPSEKDFKGPLGPFLEKFLQGAALEAKERVALFRLAWDMTLSGFGARQELYERFFFGDPVRMYQTLYNVYNKEPYKERIRAFLKESLKVFE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords 4-hydroxyphenylacetate-3-hydroxylase
publication title Crystal Structure of the Oxygenase Component (HpaB) of the 4-Hydroxyphenylacetate 3-Monooxygenase from Thermus thermophilus HB8
pubmed doi rcsb
source organism Thermus thermophilus
molecule tags Oxidoreductase
total genus 181
structure length 474
sequence length 476
ec nomenclature ec 1.14.14.9: 4-hydroxyphenylacetate 3-monooxygenase.
pdb deposition date 2007-04-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03241 HpaB 4-hydroxyphenylacetate 3-hydroxylase C terminal
A PF11794 HpaB_N 4-hydroxyphenylacetate 3-hydroxylase N terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3140.10 Mainly Alpha Orthogonal Bundle 4-hydroxybutyryl-coa dehydratase, domain 1 4-hydroxybutyryl-coa dehydratase, domain 1 2yyiA01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 2yyiA03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 2yyiA02
2ZO5A 2EBAA 2VR0A 3X0XA 2Z1QA 4IV6A 3NF4A 2R0MA 3F29A 2D29A 3BNGA 2YYMA 1UKWA 1U8VA 3MPJA 2WBIA 4Q5CA 2CX9A 3UBRA 3TORA 4L3ZA 3R7KA 3P4TA 1IVHA 2PG0A 3MKHA 3AFEA 1FS9A 2JBSA 4NXLA 2JIFA 4DOYA 4G5EA 2YYLA 3MDDA 4L38A 1UDYA 3BNFA 1SIRA 3MMOA 4L3YA 4HR3A 2IX6A 5K3HA 1GU6A 3EOMA 3D1IA 4ZYJA 3OWMA 2R0NA 3RKHA 2JBRA 3L1TA 4L3XA 2RF7A 3GM6A 2YYJA 1OAHA 3FCJA 3MPIA 4Q5BA 3D9GA 2A1TA 3AFFA 2UXWA 4Q1OA 4X28C 5K3JA 3SCEA 4ZXVA 3HWCA 3BNHA 2VIGA 2DDHA 3GNCA 2C12A 1EGCA 2JBTA 2REHA 4JEKA 4Q0TA 2C0UA 2E80A 4N5FA 3SXQA 5K3IA 3M9VA 3II9A 3LG1A 3B96A 1T9GA 1R2JA 4L1FA 1IS2A 3SF6A 3LGQA 4Q4UA 4X28A 1QDBA 3D9FA 1W07A 2ZAFA 5K3GA 4WJYA 2FONA 3OIBA 1EGDA 2RFQA 3X0YA 4IRNA 4KTOA 3BNJA 2IX5A 3MDEA 4KCFA 3UU9A 3SWOA 3D9DA 1EGEA 3MXLA 4O5MA 3GQTA 2J7AA 2YYIA 2E81A 1RX0A 2OR0A 2YYGA 2DVLA 3D9EA 3OWAA 1WS9A 3EONA 4Q17A 1FS7A 3D6BA 4OO2A 1JQIA 1FS8A 4W9UA 4RM7A 4M9AA 3S7WA 4U83A 3FO3A 3TTBA 4XVXA 2OT4A 1SIQA 4P13A 2YYKA 3PFDA 1BUCA 2RDZA
chains in the Genus database with same CATH superfamily
2ZO5A 2EBAA 2VR0A 5B5VA 3X0XA 2ZDYA 2YGWA 2PO4A 4LQQB 4MPEA 5M4KA 2Z1QA 1K8TA 4IV6A 3NF4A 1JM6A 1Y8NA 1XG2B 4H81A 2R0MA 3F29A 4G97A 2D29A 4JIOA 3BNGA 2XS1A 4J1VA 5BRKA 2YYMA 2R03A 2Q8IA 1UKWA 1Y8PA 1GKXA 1U8VA 2GBBA 3MPJA 1X90A 4V26A 2WBIA 4Q5CA 2FP2A 2CJ8A 2OEXA 2CX9A 2VF1A 3D2RA 3TZ0A 3UBRA 5M4NA 3TORA 4H85A 4L3ZA 3TZ2A 3R7KA 3P4TA 3X29A 4FF4A 3DJLA 2CJ7A 2R02A 4MPCA 2HJNA 1IVHA 2PG0A 3MKHA 4LQSB 3AFEA 3TZ5A 1FS9A 3KMLA 1XFWA 2JBSA 1RP3A 4NXLA 5M4MA 2LFWA 1XFYA 2JIFA 2CJ4A 4G5EA 2YYLA 3MDDA 4L38A 4DOYA 2Q8FA 1UDYA 3BNFA 1SIRA 3CRLA 3MMOA 4L3YA 1X91A 4HR3A 2IX6A 1Y8OA 1GU6A 3EOMA 5K3HA 3VKGA 5GJVE 3Q24A 3D1IA 1XFUA 5J6AA 5M4PA 4ZYJA 3OWMA 2R0NA 3RKHA 2PNRA 2FP1A 2AO2A 3Q0AA 2JBRA 3L1TA 4L3XA 2ZDXA 4HKRA 2RF7A 3GM6A 2YYJA 1R3BA 1OAHA 3FCJA 3MPIA 4Q5BA 2BU7A 4AI6A 1SC5A 3D9GA 2A1TA 4MP7A 3AFFA 2E0AA 2UXWA 4Q1OA 4QICA 1GKZA 4V25A 4X28C 4ZXVA 3HWCA 5K3JA 3BNHA 2XS8A 3SCEA 4E01A 2VIGA 2BU6A 2DDHA 3GNCA 2C12A 4H7QA 1EGCA 2JBTA 2Q8HA 2REHA 4JIZA 4JEKA 4Q0TA 2BU8A 2C0UA 2E80A 4HKSA 4N5FA 2F6LA 3SXQA 5K3IA 3M9VA 1XFXA 3II9A 2R05A 3LG1A 3B96A 2Q8GA 1GJVA 4AKHA 1T9GA 5B5WA 1R2JA 4L1FA 1IS2A 1SK6A 3SF6A 2AZEA 2ZKJA 3LGQA 4Q4UA 4X28A 4FF1A 4AKGA 1QDBA 1PK0A 3TZ4A 3D9FA 1W07A 2ZAFA 5K3GA 4KS9A 4WJYA 2FONA 3C46A 3OIBA 3VKHA 1EGDA 5B6BA 2RFQA 3X0YA 4MP2A 2BU5A 4IRNA 4FZ4A 4KTOA 1PI1A 3BNJA 2IX5A 3MDEA 1RJ4A 3C3LA 2XQRB 5BRMA 4KCFA 3UU9A 3SWOA 2CJ6A 3D9DA 4FF2A 1EGEA 3MXLA 2EBFX 4O5MA 3GQTA 5GJWE 2BTZA 2J7AA 2YYIA 2E81A 3VADA 1RX0A 2OR0A 2YYGA 4KSFA 2DVLA 3D9EA 4P79A 2OEVA 3OWAA 1XFVA 2EC5A 3C2PA 1WS9A 3EONA 4Q17A 5EZ3A 2CJ5A 3U33A 1LVCA 1FS7A 3CE2A 3D6BA 4AKIA 4OO2A 1JQIA 1FS8A 1XFZA 4DZYA 3N0RA 4W9UA 1Y0VA 4E00A 4RM7A 1X8ZA 2EBHX 1RJ1A 4M9AA 1S26A 4U83A 1K90A 3FO3A 4MPNA 3S7WA 4KSAA 3TTBA 2OJQA 4XVXA 2OT4A 1SIQA 2QR4A 4P13A 2YYKA 1K93A 3CRKA 2BU2A 3PFDA 4E02A 4F0XA 3Q22A 3Q23A 4FF3A 5J71A 1BUCA 2RDZA
chains in the Genus database with same CATH topology
2ZO5A 2EBAA 2VR0A 3X0XA 2Z1QA 4IV6A 3NF4A 2R0MA 3F29A 2D29A 3BNGA 2YYMA 1UKWA 1U8VA 3MPJA 2WBIA 4Q5CA 2CX9A 3UBRA 3TORA 4L3ZA 3R7KA 3P4TA 1IVHA 2PG0A 3MKHA 3AFEA 1FS9A 2JBSA 4NXLA 2JIFA 4DOYA 4G5EA 2YYLA 3MDDA 4L38A 1UDYA 3BNFA 1SIRA 3MMOA 4L3YA 4HR3A 2IX6A 5K3HA 1GU6A 3EOMA 3D1IA 4ZYJA 3OWMA 2R0NA 3RKHA 2JBRA 3L1TA 4L3XA 2RF7A 3GM6A 2YYJA 1OAHA 3FCJA 3MPIA 4Q5BA 3D9GA 2A1TA 3AFFA 2UXWA 4Q1OA 4X28C 5K3JA 3SCEA 4ZXVA 3HWCA 3BNHA 2VIGA 2DDHA 3GNCA 2C12A 1EGCA 2JBTA 2REHA 4JEKA 4Q0TA 2C0UA 2E80A 4N5FA 3SXQA 5K3IA 3M9VA 3II9A 3LG1A 3B96A 1T9GA 1R2JA 4L1FA 1IS2A 3SF6A 3LGQA 4Q4UA 4X28A 1QDBA 3D9FA 1W07A 2ZAFA 5K3GA 4WJYA 2FONA 3OIBA 1EGDA 2RFQA 3X0YA 4IRNA 4KTOA 3BNJA 2IX5A 3MDEA 4KCFA 3UU9A 3SWOA 3D9DA 1EGEA 3MXLA 4O5MA 3GQTA 2J7AA 2YYIA 2E81A 1RX0A 2OR0A 2YYGA 2DVLA 3D9EA 3OWAA 1WS9A 3EONA 4Q17A 1FS7A 3D6BA 4OO2A 1JQIA 1FS8A 4W9UA 4RM7A 4M9AA 3S7WA 4U83A 3FO3A 3TTBA 4XVXA 2OT4A 1SIQA 4P13A 2YYKA 3PFDA 1BUCA 2RDZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZO5 A;  2EBA A;  2VR0 A;  3X0X A;  2Z1Q A;  4IV6 A;  3NF4 A;  2R0M A;  3F29 A;  2D29 A;  3BNG A;  2YYM A;  1UKW A;  1U8V A;  3MPJ A;  2WBI A;  4Q5C A;  2CX9 A;  3UBR A;  3TOR A;  4L3Z A;  3R7K A;  3P4T A;  1IVH A;  2PG0 A;  3MKH A;  3AFE A;  1FS9 A;  2JBS A;  4NXL A;  2JIF A;  4DOY A;  4G5E A;  2YYL A;  3MDD A;  4L38 A;  1UDY A;  3BNF A;  1SIR A;  3MMO A;  4L3Y A;  4HR3 A;  2IX6 A;  5K3H A;  1GU6 A;  3EOM A;  3D1I A;  4ZYJ A;  3OWM A;  2R0N A;  3RKH A;  2JBR A;  3L1T A;  4L3X A;  2RF7 A;  3GM6 A;  2YYJ A;  1OAH A;  3FCJ A;  3MPI A;  4Q5B A;  3D9G A;  2A1T A;  3AFF A;  2UXW A;  4Q1O A;  4X28 C;  5K3J A;  3SCE A;  4ZXV A;  3HWC A;  3BNH A;  2VIG A;  2DDH A;  3GNC A;  2C12 A;  1EGC A;  2JBT A;  2REH A;  4JEK A;  4Q0T A;  2C0U A;  2E80 A;  4N5F A;  3SXQ A;  5K3I A;  3M9V A;  3II9 A;  3LG1 A;  3B96 A;  1T9G A;  1R2J A;  4L1F A;  1IS2 A;  3SF6 A;  3LGQ A;  4Q4U A;  4X28 A;  1QDB A;  3D9F A;  1W07 A;  2ZAF A;  5K3G A;  4WJY A;  2FON A;  3OIB A;  1EGD A;  2RFQ A;  3X0Y A;  4IRN A;  4KTO A;  3BNJ A;  2IX5 A;  3MDE A;  4KCF A;  3UU9 A;  3SWO A;  3D9D A;  1EGE A;  3MXL A;  4O5M A;  3GQT A;  2J7A A;  2YYI A;  2E81 A;  1RX0 A;  2OR0 A;  2YYG A;  2DVL A;  3D9E A;  3OWA A;  1WS9 A;  3EON A;  4Q17 A;  1FS7 A;  3D6B A;  4OO2 A;  1JQI A;  1FS8 A;  4W9U A;  4RM7 A;  4M9A A;  3S7W A;  4U83 A;  3FO3 A;  3TTB A;  4XVX A;  2OT4 A;  1SIQ A;  4P13 A;  2YYK A;  3PFD A;  1BUC A;  2RDZ A; 
#chains in the Genus database with same CATH topology
 2ZO5 A;  2EBA A;  2VR0 A;  5B5V A;  3X0X A;  2ZDY A;  2YGW A;  2PO4 A;  4LQQ B;  4MPE A;  5M4K A;  2Z1Q A;  1K8T A;  4IV6 A;  3NF4 A;  1JM6 A;  1Y8N A;  1XG2 B;  4H81 A;  2R0M A;  3F29 A;  4G97 A;  2D29 A;  4JIO A;  3BNG A;  2XS1 A;  4J1V A;  5BRK A;  2YYM A;  2R03 A;  2Q8I A;  1UKW A;  1Y8P A;  1GKX A;  1U8V A;  2GBB A;  3MPJ A;  1X90 A;  4V26 A;  2WBI A;  4Q5C A;  2FP2 A;  2CJ8 A;  2OEX A;  2CX9 A;  2VF1 A;  3D2R A;  3TZ0 A;  3UBR A;  5M4N A;  3TOR A;  4H85 A;  4L3Z A;  3TZ2 A;  3R7K A;  3P4T A;  3X29 A;  4FF4 A;  3DJL A;  2CJ7 A;  2R02 A;  4MPC A;  2HJN A;  1IVH A;  2PG0 A;  3MKH A;  4LQS B;  3AFE A;  3TZ5 A;  1FS9 A;  3KML A;  1XFW A;  2JBS A;  1RP3 A;  4NXL A;  5M4M A;  2LFW A;  1XFY A;  2JIF A;  2CJ4 A;  4G5E A;  2YYL A;  3MDD A;  4L38 A;  4DOY A;  2Q8F A;  1UDY A;  3BNF A;  1SIR A;  3CRL A;  3MMO A;  4L3Y A;  1X91 A;  4HR3 A;  2IX6 A;  1Y8O A;  1GU6 A;  3EOM A;  5K3H A;  3VKG A;  5GJV E;  3Q24 A;  3D1I A;  1XFU A;  5J6A A;  5M4P A;  4ZYJ A;  3OWM A;  2R0N A;  3RKH A;  2PNR A;  2FP1 A;  2AO2 A;  3Q0A A;  2JBR A;  3L1T A;  4L3X A;  2ZDX A;  4HKR A;  2RF7 A;  3GM6 A;  2YYJ A;  1R3B A;  1OAH A;  3FCJ A;  3MPI A;  4Q5B A;  2BU7 A;  4AI6 A;  1SC5 A;  3D9G A;  2A1T A;  4MP7 A;  3AFF A;  2E0A A;  2UXW A;  4Q1O A;  4QIC A;  1GKZ A;  4V25 A;  4X28 C;  4ZXV A;  3HWC A;  5K3J A;  3BNH A;  2XS8 A;  3SCE A;  4E01 A;  2VIG A;  2BU6 A;  2DDH A;  3GNC A;  2C12 A;  4H7Q A;  1EGC A;  2JBT A;  2Q8H A;  2REH A;  4JIZ A;  4JEK A;  4Q0T A;  2BU8 A;  2C0U A;  2E80 A;  4HKS A;  4N5F A;  2F6L A;  3SXQ A;  5K3I A;  3M9V A;  1XFX A;  3II9 A;  2R05 A;  3LG1 A;  3B96 A;  2Q8G A;  1GJV A;  4AKH A;  1T9G A;  5B5W A;  1R2J A;  4L1F A;  1IS2 A;  1SK6 A;  3SF6 A;  2AZE A;  2ZKJ A;  3LGQ A;  4Q4U A;  4X28 A;  4FF1 A;  4AKG A;  1QDB A;  1PK0 A;  3TZ4 A;  3D9F A;  1W07 A;  2ZAF A;  5K3G A;  4KS9 A;  4WJY A;  2FON A;  3C46 A;  3OIB A;  3VKH A;  1EGD A;  5B6B A;  2RFQ A;  3X0Y A;  4MP2 A;  2BU5 A;  4IRN A;  4FZ4 A;  4KTO A;  1PI1 A;  3BNJ A;  2IX5 A;  3MDE A;  1RJ4 A;  3C3L A;  2XQR B;  5BRM A;  4KCF A;  3UU9 A;  3SWO A;  2CJ6 A;  3D9D A;  4FF2 A;  1EGE A;  3MXL A;  2EBF X;  4O5M A;  3GQT A;  5GJW E;  2BTZ A;  2J7A A;  2YYI A;  2E81 A;  3VAD A;  1RX0 A;  2OR0 A;  2YYG A;  4KSF A;  2DVL A;  3D9E A;  4P79 A;  2OEV A;  3OWA A;  1XFV A;  2EC5 A;  3C2P A;  1WS9 A;  3EON A;  4Q17 A;  5EZ3 A;  2CJ5 A;  3U33 A;  1LVC A;  1FS7 A;  3CE2 A;  3D6B A;  4AKI A;  4OO2 A;  1JQI A;  1FS8 A;  1XFZ A;  4DZY A;  3N0R A;  4W9U A;  1Y0V A;  4E00 A;  4RM7 A;  1X8Z A;  2EBH X;  1RJ1 A;  4M9A A;  1S26 A;  4U83 A;  1K90 A;  3FO3 A;  4MPN A;  3S7W A;  4KSA A;  3TTB A;  2OJQ A;  4XVX A;  2OT4 A;  1SIQ A;  2QR4 A;  4P13 A;  2YYK A;  1K93 A;  3CRK A;  2BU2 A;  3PFD A;  4E02 A;  4F0X A;  3Q22 A;  3Q23 A;  4FF3 A;  5J71 A;  1BUC A;  2RDZ A; 
#chains in the Genus database with same CATH homology
 2ZO5 A;  2EBA A;  2VR0 A;  3X0X A;  2Z1Q A;  4IV6 A;  3NF4 A;  2R0M A;  3F29 A;  2D29 A;  3BNG A;  2YYM A;  1UKW A;  1U8V A;  3MPJ A;  2WBI A;  4Q5C A;  2CX9 A;  3UBR A;  3TOR A;  4L3Z A;  3R7K A;  3P4T A;  1IVH A;  2PG0 A;  3MKH A;  3AFE A;  1FS9 A;  2JBS A;  4NXL A;  2JIF A;  4DOY A;  4G5E A;  2YYL A;  3MDD A;  4L38 A;  1UDY A;  3BNF A;  1SIR A;  3MMO A;  4L3Y A;  4HR3 A;  2IX6 A;  5K3H A;  1GU6 A;  3EOM A;  3D1I A;  4ZYJ A;  3OWM A;  2R0N A;  3RKH A;  2JBR A;  3L1T A;  4L3X A;  2RF7 A;  3GM6 A;  2YYJ A;  1OAH A;  3FCJ A;  3MPI A;  4Q5B A;  3D9G A;  2A1T A;  3AFF A;  2UXW A;  4Q1O A;  4X28 C;  5K3J A;  3SCE A;  4ZXV A;  3HWC A;  3BNH A;  2VIG A;  2DDH A;  3GNC A;  2C12 A;  1EGC A;  2JBT A;  2REH A;  4JEK A;  4Q0T A;  2C0U A;  2E80 A;  4N5F A;  3SXQ A;  5K3I A;  3M9V A;  3II9 A;  3LG1 A;  3B96 A;  1T9G A;  1R2J A;  4L1F A;  1IS2 A;  3SF6 A;  3LGQ A;  4Q4U A;  4X28 A;  1QDB A;  3D9F A;  1W07 A;  2ZAF A;  5K3G A;  4WJY A;  2FON A;  3OIB A;  1EGD A;  2RFQ A;  3X0Y A;  4IRN A;  4KTO A;  3BNJ A;  2IX5 A;  3MDE A;  4KCF A;  3UU9 A;  3SWO A;  3D9D A;  1EGE A;  3MXL A;  4O5M A;  3GQT A;  2J7A A;  2YYI A;  2E81 A;  1RX0 A;  2OR0 A;  2YYG A;  2DVL A;  3D9E A;  3OWA A;  1WS9 A;  3EON A;  4Q17 A;  1FS7 A;  3D6B A;  4OO2 A;  1JQI A;  1FS8 A;  4W9U A;  4RM7 A;  4M9A A;  3S7W A;  4U83 A;  3FO3 A;  3TTB A;  4XVX A;  2OT4 A;  1SIQ A;  4P13 A;  2YYK A;  3PFD A;  1BUC A;  2RDZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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