2YYIA

Crystal structure of the oxygenase component (hpab) of 4-hydroxyphenylacetate 3-monooxygenase complexed with fad
Total Genus 181
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
181
sequence length
476
structure length
474
Chain Sequence
ARTGAEYIEALKTRPPNLWYKGEKVEDPTTHPVFRGIVRTMAALYDLQHDPRYREVLTYEEEGKRHGMSFLIPKTKEDLKRRGQAYKLWADQNLGMMGRSPDYLNAVVMAYAASADYFGEFAENVRNYYRYLRDQDLATTHALTNPQVNRARPPSGQPDPYIPVGVVKQTEKGIVVRGARMTATFPLADEVLIFPLLQAGSEKYALAFALPTSTPGLHFVCREALVGGDSPFDHPLSSRVEEMDCLVIFDDVLVPWERVFILGNVELCNNAYAATGALNHMAHQVVALKTAKTEAFLGVAALMAEGIGADVYGHVQEKIAEIIVYLEAMRAFWTRAEEEAKENAYGLLVPDRGALDGARNLYPRLYPRIREILEQIGASGLITLPSEKDFKGPLGPFLEKFLQGAALEAKERVALFRLAWDMTLSGFGARQELYERFFFGDPVRMYQTLYNVYNKEPYKERIRAFLKESLKVFE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Oxidoreductase
molecule keywords 4-hydroxyphenylacetate-3-hydroxylase
publication title Crystal Structure of the Oxygenase Component (HpaB) of the 4-Hydroxyphenylacetate 3-Monooxygenase from Thermus thermophilus HB8
pubmed doi rcsb
source organism Thermus thermophilus
total genus 181
structure length 474
sequence length 476
ec nomenclature ec 1.14.14.9: 4-hydroxyphenylacetate 3-monooxygenase.
pdb deposition date 2007-04-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03241 HpaB 4-hydroxyphenylacetate 3-hydroxylase C terminal
A PF11794 HpaB_N 4-hydroxyphenylacetate 3-hydroxylase N terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3140.10 Mainly Alpha Orthogonal Bundle 4-hydroxybutyryl-coa dehydratase, domain 1 4-hydroxybutyryl-coa dehydratase, domain 1 2yyiA01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 2yyiA03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 2yyiA02
1BUCA 3OWAA 2YYLA 2RDZA 3OIBA 3FCJA 3PFDA 5K3IA 2EBAA 4M9AA 3EONA 4HR3A 3HWCA 2D29A 4L3YA 4L3XA 2JIFA 3UU9A 2VR0A 3X0XA 4U83A 3D9EA 1EGEA 1QDBA 2PG0A 4N5FA 1IVHA 2YYMA 3SF6A 3F29A 1FS8A 3D9FA 3LGQA 5K3JA 3UBRA 3B96A 3D6BA 3BNHA 3S7WA 2DDHA 3D9DA 1EGDA 2JBRA 2C0UA 1IS2A 3MPJA 2YYGA 4G5EA 3OWMA 4O5MA 4P13A 4DOYA 3LG1A 1UDYA 1WS9A 1RX0A 4Q4UA 1UKWA 3FO3A 1U8VA 4Q5CA 4OO2A 3MXLA 1JQIA 2RFQA 3X0YA 1FS7A 1EGCA 4L3ZA 1SIQA 1R2JA 4Q1OA 3GM6A 3BNJA 2YYKA 2E81A 3SXQA 2UXWA 3AFEA 2ZAFA 4L1FA 4NXLA 2E80A 2RF7A 2YYIA 3EOMA 2ZO5A 4X28C 4X28A 4JEKA 3SCEA 3II9A 4Q0TA 2IX5A 3AFFA 1OAHA 3M9VA 5K3GA 2REHA 4WJYA 3SWOA 1W07A 2OT4A 3NF4A 1FS9A 3L1TA 4KTOA 2WBIA 3BNFA 2DVLA 3MDDA 4W9UA 3GNCA 2J7AA 3D9GA 3GQTA 3MPIA 4KCFA 3P4TA 2Z1QA 2YYJA 2OR0A 2CX9A 4ZYJA 2VIGA 4IRNA 3TORA 2JBTA 5K3HA 2R0NA 3BNGA 2JBSA 1GU6A 4RM7A 2A1TA 4XVXA 3RKHA 4ZXVA 2FONA 3MKHA 3R7KA 1T9GA 2C12A 3MDEA 4IV6A 4Q17A 1SIRA 3TTBA 4L38A 2R0MA 4Q5BA 3D1IA 3MMOA 2IX6A
chains in the Genus database with same CATH superfamily
2XS1A 1XFVA 1XFZA 1BUCA 2R03A 4JIOA 4J1VA 3OWAA 3C3LA 2YYLA 2RDZA 4FF1A 3OIBA 3FCJA 1RP3A 3PFDA 5K3IA 2EBAA 2E0AA 4M9AA 3EONA 4HR3A 3HWCA 1XG2B 2D29A 2EC5A 4L3YA 2R02A 4L3XA 3TZ0A 2JIFA 3UU9A 2VR0A 1GKZA 3X0XA 4H7QA 4U83A 4E01A 5BRKA 5GJVE 1LVCA 2PO4A 3D2RA 3C46A 3D9EA 3DJLA 1EGEA 1QDBA 2PG0A 4N5FA 4MP2A 1IVHA 2YYMA 1GJVA 5BRMA 3SF6A 3F29A 1JM6A 1Y8OA 1FS8A 4DZYA 5M4PA 3Q23A 4V25A 1XFUA 4HKSA 1Y0VA 5EZ3A 3D9FA 1RJ4A 4H85A 4FF4A 3LGQA 2OJQA 5K3JA 3UBRA 3B96A 3KMLA 4LQQB 3D6BA 3BNHA 3S7WA 1XFXA 2DDHA 3CE2A 3D9DA 1EGDA 2JBRA 2C0UA 4G97A 3VADA 1IS2A 3MPJA 2YYGA 4G5EA 3OWMA 1RJ1A 4O5MA 2GBBA 4FZ4A 4LQSB 4P13A 4DOYA 2AO2A 3LG1A 5GJWE 1UDYA 1WS9A 1RX0A 4Q4UA 1UKWA 3FO3A 4MPEA 2XQRB 2R05A 1U8VA 4Q5CA 4OO2A 4FF2A 3MXLA 4KSAA 1X91A 2CJ6A 1JQIA 2OEVA 2RFQA 4MP7A 3X0YA 2BU7A 1FS7A 1EGCA 1K90A 2EBFX 1SIQA 4L3ZA 3TZ2A 4V26A 4AI6A 1R2JA 2F6LA 3GM6A 4Q1OA 1SC5A 3BNJA 4HKRA 4KS9A 5J71A 4MPNA 2YYKA 2E81A 3SXQA 2UXWA 3AFEA 5M4NA 5J6AA 3Q24A 2ZAFA 4L1FA 4NXLA 4F0XA 2ZDYA 2ZKJA 1SK6A 2FP1A 2E80A 2Q8FA 2OEXA 2YYIA 2RF7A 3EOMA 2ZO5A 4X28C 4X28A 3Q22A 2BTZA 4JEKA 1S26A 3SCEA 3II9A 1PI1A 4JIZA 3C2PA 3VKGA 4Q0TA 2IX5A 4AKGA 4AKHA 3AFFA 1OAHA 3M9VA 3TZ4A 3Q0AA 1K8TA 5K3GA 1Y8NA 2REHA 4WJYA 3SWOA 2AZEA 4KSFA 1W07A 2YGWA 3CRLA 3NF4A 1FS9A 3L1TA 4KTOA 2OT4A 5B6BA 4E02A 1XFWA 5M4KA 2WBIA 2CJ8A 2DVLA 3BNFA 3MDDA 3N0RA 3TZ5A 4W9UA 3GNCA 2J7AA 3D9GA 2Q8HA 3VKHA 2FP2A 3CRKA 3GQTA 5B5VA 2BU6A 1R3BA 3MPIA 4KCFA 3P4TA 2Z1QA 4QICA 3X29A 2YYJA 5M4MA 2OR0A 4H81A 4P79A 1X8ZA 2CX9A 4ZYJA 2HJNA 1X90A 2VIGA 4IRNA 2Q8IA 2EBHX 2XS8A 2JBTA 3TORA 2Q8GA 5B5WA 4MPCA 5K3HA 3U33A 2R0NA 3BNGA 2JBSA 1GKXA 2VF1A 1GU6A 4RM7A 2A1TA 1XFYA 1K93A 2CJ7A 4XVXA 3RKHA 2LFWA 2BU5A 4ZXVA 2FONA 2PNRA 2CJ5A 3MKHA 3R7KA 1T9GA 2C12A 3MDEA 4IV6A 4AKIA 4Q17A 1Y8PA 2BU2A 4E00A 1SIRA 3TTBA 4L38A 2QR4A 2R0MA 4Q5BA 1PK0A 2BU8A 2CJ4A 3D1IA 2ZDXA 4FF3A 3MMOA 2IX6A
chains in the Genus database with same CATH topology
1BUCA 3OWAA 2YYLA 2RDZA 3OIBA 3FCJA 3PFDA 5K3IA 2EBAA 4M9AA 3EONA 4HR3A 3HWCA 2D29A 4L3YA 4L3XA 2JIFA 3UU9A 2VR0A 3X0XA 4U83A 3D9EA 1EGEA 1QDBA 2PG0A 4N5FA 1IVHA 2YYMA 3SF6A 3F29A 1FS8A 3D9FA 3LGQA 5K3JA 3UBRA 3B96A 3D6BA 3BNHA 3S7WA 2DDHA 3D9DA 1EGDA 2JBRA 2C0UA 1IS2A 3MPJA 2YYGA 4G5EA 3OWMA 4O5MA 4P13A 4DOYA 3LG1A 1UDYA 1WS9A 1RX0A 4Q4UA 1UKWA 3FO3A 1U8VA 4Q5CA 4OO2A 3MXLA 1JQIA 2RFQA 3X0YA 1FS7A 1EGCA 4L3ZA 1SIQA 1R2JA 4Q1OA 3GM6A 3BNJA 2YYKA 2E81A 3SXQA 2UXWA 3AFEA 2ZAFA 4L1FA 4NXLA 2E80A 2RF7A 2YYIA 3EOMA 2ZO5A 4X28C 4X28A 4JEKA 3SCEA 3II9A 4Q0TA 2IX5A 3AFFA 1OAHA 3M9VA 5K3GA 2REHA 4WJYA 3SWOA 1W07A 2OT4A 3NF4A 1FS9A 3L1TA 4KTOA 2WBIA 3BNFA 2DVLA 3MDDA 4W9UA 3GNCA 2J7AA 3D9GA 3GQTA 3MPIA 4KCFA 3P4TA 2Z1QA 2YYJA 2OR0A 2CX9A 4ZYJA 2VIGA 4IRNA 3TORA 2JBTA 5K3HA 2R0NA 3BNGA 2JBSA 1GU6A 4RM7A 2A1TA 4XVXA 3RKHA 4ZXVA 2FONA 3MKHA 3R7KA 1T9GA 2C12A 3MDEA 4IV6A 4Q17A 1SIRA 3TTBA 4L38A 2R0MA 4Q5BA 3D1IA 3MMOA 2IX6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BUC A;  3OWA A;  2YYL A;  2RDZ A;  3OIB A;  3FCJ A;  3PFD A;  5K3I A;  2EBA A;  4M9A A;  3EON A;  4HR3 A;  3HWC A;  2D29 A;  4L3Y A;  4L3X A;  2JIF A;  3UU9 A;  2VR0 A;  3X0X A;  4U83 A;  3D9E A;  1EGE A;  1QDB A;  2PG0 A;  4N5F A;  1IVH A;  2YYM A;  3SF6 A;  3F29 A;  1FS8 A;  3D9F A;  3LGQ A;  5K3J A;  3UBR A;  3B96 A;  3D6B A;  3BNH A;  3S7W A;  2DDH A;  3D9D A;  1EGD A;  2JBR A;  2C0U A;  1IS2 A;  3MPJ A;  2YYG A;  4G5E A;  3OWM A;  4O5M A;  4P13 A;  4DOY A;  3LG1 A;  1UDY A;  1WS9 A;  1RX0 A;  4Q4U A;  1UKW A;  3FO3 A;  1U8V A;  4Q5C A;  4OO2 A;  3MXL A;  1JQI A;  2RFQ A;  3X0Y A;  1FS7 A;  1EGC A;  4L3Z A;  1SIQ A;  1R2J A;  4Q1O A;  3GM6 A;  3BNJ A;  2YYK A;  2E81 A;  3SXQ A;  2UXW A;  3AFE A;  2ZAF A;  4L1F A;  4NXL A;  2E80 A;  2RF7 A;  2YYI A;  3EOM A;  2ZO5 A;  4X28 C;  4X28 A;  4JEK A;  3SCE A;  3II9 A;  4Q0T A;  2IX5 A;  3AFF A;  1OAH A;  3M9V A;  5K3G A;  2REH A;  4WJY A;  3SWO A;  1W07 A;  2OT4 A;  3NF4 A;  1FS9 A;  3L1T A;  4KTO A;  2WBI A;  3BNF A;  2DVL A;  3MDD A;  4W9U A;  3GNC A;  2J7A A;  3D9G A;  3GQT A;  3MPI A;  4KCF A;  3P4T A;  2Z1Q A;  2YYJ A;  2OR0 A;  2CX9 A;  4ZYJ A;  2VIG A;  4IRN A;  3TOR A;  2JBT A;  5K3H A;  2R0N A;  3BNG A;  2JBS A;  1GU6 A;  4RM7 A;  2A1T A;  4XVX A;  3RKH A;  4ZXV A;  2FON A;  3MKH A;  3R7K A;  1T9G A;  2C12 A;  3MDE A;  4IV6 A;  4Q17 A;  1SIR A;  3TTB A;  4L38 A;  2R0M A;  4Q5B A;  3D1I A;  3MMO A;  2IX6 A; 
#chains in the Genus database with same CATH topology
 2XS1 A;  1XFV A;  1XFZ A;  1BUC A;  2R03 A;  4JIO A;  4J1V A;  3OWA A;  3C3L A;  2YYL A;  2RDZ A;  4FF1 A;  3OIB A;  3FCJ A;  1RP3 A;  3PFD A;  5K3I A;  2EBA A;  2E0A A;  4M9A A;  3EON A;  4HR3 A;  3HWC A;  1XG2 B;  2D29 A;  2EC5 A;  4L3Y A;  2R02 A;  4L3X A;  3TZ0 A;  2JIF A;  3UU9 A;  2VR0 A;  1GKZ A;  3X0X A;  4H7Q A;  4U83 A;  4E01 A;  5BRK A;  5GJV E;  1LVC A;  2PO4 A;  3D2R A;  3C46 A;  3D9E A;  3DJL A;  1EGE A;  1QDB A;  2PG0 A;  4N5F A;  4MP2 A;  1IVH A;  2YYM A;  1GJV A;  5BRM A;  3SF6 A;  3F29 A;  1JM6 A;  1Y8O A;  1FS8 A;  4DZY A;  5M4P A;  3Q23 A;  4V25 A;  1XFU A;  4HKS A;  1Y0V A;  5EZ3 A;  3D9F A;  1RJ4 A;  4H85 A;  4FF4 A;  3LGQ A;  2OJQ A;  5K3J A;  3UBR A;  3B96 A;  3KML A;  4LQQ B;  3D6B A;  3BNH A;  3S7W A;  1XFX A;  2DDH A;  3CE2 A;  3D9D A;  1EGD A;  2JBR A;  2C0U A;  4G97 A;  3VAD A;  1IS2 A;  3MPJ A;  2YYG A;  4G5E A;  3OWM A;  1RJ1 A;  4O5M A;  2GBB A;  4FZ4 A;  4LQS B;  4P13 A;  4DOY A;  2AO2 A;  3LG1 A;  5GJW E;  1UDY A;  1WS9 A;  1RX0 A;  4Q4U A;  1UKW A;  3FO3 A;  4MPE A;  2XQR B;  2R05 A;  1U8V A;  4Q5C A;  4OO2 A;  4FF2 A;  3MXL A;  4KSA A;  1X91 A;  2CJ6 A;  1JQI A;  2OEV A;  2RFQ A;  4MP7 A;  3X0Y A;  2BU7 A;  1FS7 A;  1EGC A;  1K90 A;  2EBF X;  1SIQ A;  4L3Z A;  3TZ2 A;  4V26 A;  4AI6 A;  1R2J A;  2F6L A;  3GM6 A;  4Q1O A;  1SC5 A;  3BNJ A;  4HKR A;  4KS9 A;  5J71 A;  4MPN A;  2YYK A;  2E81 A;  3SXQ A;  2UXW A;  3AFE A;  5M4N A;  5J6A A;  3Q24 A;  2ZAF A;  4L1F A;  4NXL A;  4F0X A;  2ZDY A;  2ZKJ A;  1SK6 A;  2FP1 A;  2E80 A;  2Q8F A;  2OEX A;  2YYI A;  2RF7 A;  3EOM A;  2ZO5 A;  4X28 C;  4X28 A;  3Q22 A;  2BTZ A;  4JEK A;  1S26 A;  3SCE A;  3II9 A;  1PI1 A;  4JIZ A;  3C2P A;  3VKG A;  4Q0T A;  2IX5 A;  4AKG A;  4AKH A;  3AFF A;  1OAH A;  3M9V A;  3TZ4 A;  3Q0A A;  1K8T A;  5K3G A;  1Y8N A;  2REH A;  4WJY A;  3SWO A;  2AZE A;  4KSF A;  1W07 A;  2YGW A;  3CRL A;  3NF4 A;  1FS9 A;  3L1T A;  4KTO A;  2OT4 A;  5B6B A;  4E02 A;  1XFW A;  5M4K A;  2WBI A;  2CJ8 A;  2DVL A;  3BNF A;  3MDD A;  3N0R A;  3TZ5 A;  4W9U A;  3GNC A;  2J7A A;  3D9G A;  2Q8H A;  3VKH A;  2FP2 A;  3CRK A;  3GQT A;  5B5V A;  2BU6 A;  1R3B A;  3MPI A;  4KCF A;  3P4T A;  2Z1Q A;  4QIC A;  3X29 A;  2YYJ A;  5M4M A;  2OR0 A;  4H81 A;  4P79 A;  1X8Z A;  2CX9 A;  4ZYJ A;  2HJN A;  1X90 A;  2VIG A;  4IRN A;  2Q8I A;  2EBH X;  2XS8 A;  2JBT A;  3TOR A;  2Q8G A;  5B5W A;  4MPC A;  5K3H A;  3U33 A;  2R0N A;  3BNG A;  2JBS A;  1GKX A;  2VF1 A;  1GU6 A;  4RM7 A;  2A1T A;  1XFY A;  1K93 A;  2CJ7 A;  4XVX A;  3RKH A;  2LFW A;  2BU5 A;  4ZXV A;  2FON A;  2PNR A;  2CJ5 A;  3MKH A;  3R7K A;  1T9G A;  2C12 A;  3MDE A;  4IV6 A;  4AKI A;  4Q17 A;  1Y8P A;  2BU2 A;  4E00 A;  1SIR A;  3TTB A;  4L38 A;  2QR4 A;  2R0M A;  4Q5B A;  1PK0 A;  2BU8 A;  2CJ4 A;  3D1I A;  2ZDX A;  4FF3 A;  3MMO A;  2IX6 A; 
#chains in the Genus database with same CATH homology
 1BUC A;  3OWA A;  2YYL A;  2RDZ A;  3OIB A;  3FCJ A;  3PFD A;  5K3I A;  2EBA A;  4M9A A;  3EON A;  4HR3 A;  3HWC A;  2D29 A;  4L3Y A;  4L3X A;  2JIF A;  3UU9 A;  2VR0 A;  3X0X A;  4U83 A;  3D9E A;  1EGE A;  1QDB A;  2PG0 A;  4N5F A;  1IVH A;  2YYM A;  3SF6 A;  3F29 A;  1FS8 A;  3D9F A;  3LGQ A;  5K3J A;  3UBR A;  3B96 A;  3D6B A;  3BNH A;  3S7W A;  2DDH A;  3D9D A;  1EGD A;  2JBR A;  2C0U A;  1IS2 A;  3MPJ A;  2YYG A;  4G5E A;  3OWM A;  4O5M A;  4P13 A;  4DOY A;  3LG1 A;  1UDY A;  1WS9 A;  1RX0 A;  4Q4U A;  1UKW A;  3FO3 A;  1U8V A;  4Q5C A;  4OO2 A;  3MXL A;  1JQI A;  2RFQ A;  3X0Y A;  1FS7 A;  1EGC A;  4L3Z A;  1SIQ A;  1R2J A;  4Q1O A;  3GM6 A;  3BNJ A;  2YYK A;  2E81 A;  3SXQ A;  2UXW A;  3AFE A;  2ZAF A;  4L1F A;  4NXL A;  2E80 A;  2RF7 A;  2YYI A;  3EOM A;  2ZO5 A;  4X28 C;  4X28 A;  4JEK A;  3SCE A;  3II9 A;  4Q0T A;  2IX5 A;  3AFF A;  1OAH A;  3M9V A;  5K3G A;  2REH A;  4WJY A;  3SWO A;  1W07 A;  2OT4 A;  3NF4 A;  1FS9 A;  3L1T A;  4KTO A;  2WBI A;  3BNF A;  2DVL A;  3MDD A;  4W9U A;  3GNC A;  2J7A A;  3D9G A;  3GQT A;  3MPI A;  4KCF A;  3P4T A;  2Z1Q A;  2YYJ A;  2OR0 A;  2CX9 A;  4ZYJ A;  2VIG A;  4IRN A;  3TOR A;  2JBT A;  5K3H A;  2R0N A;  3BNG A;  2JBS A;  1GU6 A;  4RM7 A;  2A1T A;  4XVX A;  3RKH A;  4ZXV A;  2FON A;  3MKH A;  3R7K A;  1T9G A;  2C12 A;  3MDE A;  4IV6 A;  4Q17 A;  1SIR A;  3TTB A;  4L38 A;  2R0M A;  4Q5B A;  3D1I A;  3MMO A;  2IX6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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