4P79A

Crystal structure of mouse claudin-15
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
189
structure length
181
Chain Sequence
SEFMSVAVETFGFFMSALGLLMLGLTLSNSYWRVSTNTIFENLWYSCATDSLGVSNCWDFPSMLALSGYVQGCRALMITAILLGFLGLFLGMVGLRATNVGNMDLSKKAKLLAIAGTLHILAGACGMVAISWYAVNITTDFFNPLYAGTKYELGPALYLGWSASLLSILGGICVFSTAAAS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Claudin-15
publication title Crystal structure of a claudin provides insight into the architecture of tight junctions.
pubmed doi rcsb
source organism Mus musculus
molecule tags Cell adhesion
total genus 59
structure length 181
sequence length 189
ec nomenclature
pdb deposition date 2014-03-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00822 PMP22_Claudin PMP-22/EMP/MP20/Claudin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.140.150 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A; domain 3 4p79A00
3X29A 5GJVE 4P79A 5GJWE
chains in the Genus database with same CATH superfamily
2R05A 4L3YA 3LGQA 4HR3A 4P79A 2E80A 3GM6A 4L38A 4Q4UA 4ZYJA 1X90A 2IX5A 4LQQB 5M4MA 2OEXA 1R2JA 2VR0A 3MKHA 2YYIA 2BTZA 2BU5A 3AFEA 3PFDA 5K3JA 3TORA 4AKHA 2JBTA 1IS2A 2XQRB 2IX6A 2GBBA 4W9UA 3BNJA 2D29A 1SIQA 4LQSB 5BRKA 4N5FA 4F0XA 3TZ0A 4OO2A 4L3XA 2ZDYA 4KCFA 4KSFA 3Q24A 2XS1A 2YYGA 1RJ1A 2Q8FA 3CRLA 1T9GA 4JIZA 3GQTA 3M9VA 5M4NA 2A1TA 4Q0TA 2F6LA 2YYJA 4X28C 2BU2A 2UXWA 4L1FA 4NXLA 2Q8IA 1RJ4A 4FF1A 1Y8OA 2BU7A 3OWMA 1K93A 1GJVA 2EBFX 3KMLA 3D9FA 4WJYA 3TZ5A 5M4PA 2VF1A 2EBHX 2C0UA 2Q8GA 3BNFA 2R0MA 1JM6A 2OJQA 3C3LA 2YYKA 2EBAA 1XG2B 3D9EA 1K90A 4H81A 4FZ4A 3UU9A 1SIRA 2HJNA 2R03A 2PO4A 4MPNA 2J7AA 3TZ4A 2CX9A 4X28A 1GKZA 2DDHA 3UBRA 2WBIA 4G5EA 4FF2A 1X91A 1SC5A 4HKRA 5B5WA 3Q22A 3C46A 4FF3A 1EGDA 3VKHA 3MXLA 2RFQA 2CJ4A 3D2RA 1S26A 2FONA 2VIGA 1Y8PA 1GKXA 1XFXA 4IV6A 4E00A 4E01A 4O5MA 1K8TA 1W07A 2YYMA 5GJWE 3D1IA 1OAHA 1RP3A 2OEVA 2Z1QA 3P4TA 4MP7A 3II9A 4MP2A 2YGWA 3CRKA 1SK6A 1U8VA 2CJ6A 3HWCA 2REHA 2Q8HA 4V25A 1FS9A 2BU8A 3D9DA 4QICA 1EGEA 3AFFA 1XFWA 3CE2A 4JIOA 2JBSA 4P13A 4MPCA 3OIBA 2E81A 3MDDA 2BU6A 1Y8NA 3BNGA 3FO3A 4L3ZA 4XVXA 3X0YA 4KTOA 2YYLA 2RF7A 4Q5CA 3MPJA 1UDYA 2C12A 1PK0A 4JEKA 3N0RA 4H85A 4KSAA 1XFVA 3VADA 1FS7A 1XFZA 3MMOA 1IVHA 2PNRA 2PG0A 3EOMA 3L1TA 4U83A 3NF4A 2ZKJA 3MDEA 4Q5BA 5GJVE 1BUCA 2ZAFA 4J1VA 2XS8A 3C2PA 2AO2A 2FP2A 5J6AA 3EONA 1X8ZA 5K3GA 1QDBA 4E02A 3SXQA 2OT4A 3VKGA 2R0NA 1FS8A 4RM7A 1WS9A 3MPIA 1Y0VA 4MPEA 3FCJA 3SCEA 1LVCA 2RDZA 2CJ7A 3RKHA 2R02A 5K3HA 1JQIA 3R7KA 1UKWA 4ZXVA 3TZ2A 4KS9A 3LG1A 3X29A 4FF4A 3D6BA 4AI6A 4Q1OA 3Q0AA 1RX0A 4IRNA 2JIFA 3SWOA 4DOYA 5M4KA 1GU6A 2LFWA 2ZO5A 1XFUA 3S7WA 3TTBA 3X0XA 5B5VA 2FP1A 3BNHA 4AKIA 3F29A 2EC5A 2CJ8A 3SF6A 2CJ5A 3OWAA 4AKGA 4HKSA 2E0AA 5J71A 5BRMA 2ZDXA 1R3BA 1PI1A 3GNCA 5B6BA 4DZYA 1XFYA 4G97A 2QR4A 4H7QA 3Q23A 1EGCA 2JBRA 3D9GA 2AZEA 4V26A 2DVLA 4Q17A 2OR0A 5K3IA 4M9AA 3B96A
chains in the Genus database with same CATH topology
2EBFX 1SK6A 3VKGA 4P79A 2VF1A 2EBHX 1Y0VA 4QICA 1LVCA 1XFWA 3CE2A 3C3LA 4AKHA 1K90A 4FZ4A 4FF4A 4KS9A 3X29A 4AI6A 2GBBA 2PO4A 3Q0AA 1PK0A 2LFWA 3N0RA 4KSAA 1XFVA 1XFUA 4F0XA 1XFZA 2FP1A 4FF2A 4HKRA 1SC5A 3Q22A 3C46A 4AKIA 4FF3A 4KSFA 2EC5A 3Q24A 4AKGA 4HKSA 3VKHA 3KMLA 1S26A 5GJVE 2YGWA 1XFYA 1XFXA 2QR4A 4G97A 3Q23A 2AO2A 2FP2A 1K8TA 2F6LA 3C2PA 1RP3A 2AZEA 5GJWE 4FF1A 1K93A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3X29 A;  5GJV E;  4P79 A;  5GJW E; 
#chains in the Genus database with same CATH topology
 2R05 A;  4L3Y A;  3LGQ A;  4HR3 A;  4P79 A;  2E80 A;  3GM6 A;  4L38 A;  4Q4U A;  4ZYJ A;  1X90 A;  2IX5 A;  4LQQ B;  5M4M A;  2OEX A;  1R2J A;  2VR0 A;  3MKH A;  2YYI A;  2BTZ A;  2BU5 A;  3AFE A;  3PFD A;  5K3J A;  3TOR A;  4AKH A;  2JBT A;  1IS2 A;  2XQR B;  2IX6 A;  2GBB A;  4W9U A;  3BNJ A;  2D29 A;  1SIQ A;  4LQS B;  5BRK A;  4N5F A;  4F0X A;  3TZ0 A;  4OO2 A;  4L3X A;  2ZDY A;  4KCF A;  4KSF A;  3Q24 A;  2XS1 A;  2YYG A;  1RJ1 A;  2Q8F A;  3CRL A;  1T9G A;  4JIZ A;  3GQT A;  3M9V A;  5M4N A;  2A1T A;  4Q0T A;  2F6L A;  2YYJ A;  4X28 C;  2BU2 A;  2UXW A;  4L1F A;  4NXL A;  2Q8I A;  1RJ4 A;  4FF1 A;  1Y8O A;  2BU7 A;  3OWM A;  1K93 A;  1GJV A;  2EBF X;  3KML A;  3D9F A;  4WJY A;  3TZ5 A;  5M4P A;  2VF1 A;  2EBH X;  2C0U A;  2Q8G A;  3BNF A;  2R0M A;  1JM6 A;  2OJQ A;  3C3L A;  2YYK A;  2EBA A;  1XG2 B;  3D9E A;  1K90 A;  4H81 A;  4FZ4 A;  3UU9 A;  1SIR A;  2HJN A;  2R03 A;  2PO4 A;  4MPN A;  2J7A A;  3TZ4 A;  2CX9 A;  4X28 A;  1GKZ A;  2DDH A;  3UBR A;  2WBI A;  4G5E A;  4FF2 A;  1X91 A;  1SC5 A;  4HKR A;  5B5W A;  3Q22 A;  3C46 A;  4FF3 A;  1EGD A;  3VKH A;  3MXL A;  2RFQ A;  2CJ4 A;  3D2R A;  1S26 A;  2FON A;  2VIG A;  1Y8P A;  1GKX A;  1XFX A;  4IV6 A;  4E00 A;  4E01 A;  4O5M A;  1K8T A;  1W07 A;  2YYM A;  5GJW E;  3D1I A;  1OAH A;  1RP3 A;  2OEV A;  2Z1Q A;  3P4T A;  4MP7 A;  3II9 A;  4MP2 A;  2YGW A;  3CRK A;  1SK6 A;  1U8V A;  2CJ6 A;  3HWC A;  2REH A;  2Q8H A;  4V25 A;  1FS9 A;  2BU8 A;  3D9D A;  4QIC A;  1EGE A;  3AFF A;  1XFW A;  3CE2 A;  4JIO A;  2JBS A;  4P13 A;  4MPC A;  3OIB A;  2E81 A;  3MDD A;  2BU6 A;  1Y8N A;  3BNG A;  3FO3 A;  4L3Z A;  4XVX A;  3X0Y A;  4KTO A;  2YYL A;  2RF7 A;  4Q5C A;  3MPJ A;  1UDY A;  2C12 A;  1PK0 A;  4JEK A;  3N0R A;  4H85 A;  4KSA A;  1XFV A;  3VAD A;  1FS7 A;  1XFZ A;  3MMO A;  1IVH A;  2PNR A;  2PG0 A;  3EOM A;  3L1T A;  4U83 A;  3NF4 A;  2ZKJ A;  3MDE A;  4Q5B A;  5GJV E;  1BUC A;  2ZAF A;  4J1V A;  2XS8 A;  3C2P A;  2AO2 A;  2FP2 A;  5J6A A;  3EON A;  1X8Z A;  5K3G A;  1QDB A;  4E02 A;  3SXQ A;  2OT4 A;  3VKG A;  2R0N A;  1FS8 A;  4RM7 A;  1WS9 A;  3MPI A;  1Y0V A;  4MPE A;  3FCJ A;  3SCE A;  1LVC A;  2RDZ A;  2CJ7 A;  3RKH A;  2R02 A;  5K3H A;  1JQI A;  3R7K A;  1UKW A;  4ZXV A;  3TZ2 A;  4KS9 A;  3LG1 A;  3X29 A;  4FF4 A;  3D6B A;  4AI6 A;  4Q1O A;  3Q0A A;  1RX0 A;  4IRN A;  2JIF A;  3SWO A;  4DOY A;  5M4K A;  1GU6 A;  2LFW A;  2ZO5 A;  1XFU A;  3S7W A;  3TTB A;  3X0X A;  5B5V A;  2FP1 A;  3BNH A;  4AKI A;  3F29 A;  2EC5 A;  2CJ8 A;  3SF6 A;  2CJ5 A;  3OWA A;  4AKG A;  4HKS A;  2E0A A;  5J71 A;  5BRM A;  2ZDX A;  1R3B A;  1PI1 A;  3GNC A;  5B6B A;  4DZY A;  1XFY A;  4G97 A;  2QR4 A;  4H7Q A;  3Q23 A;  1EGC A;  2JBR A;  3D9G A;  2AZE A;  4V26 A;  2DVL A;  4Q17 A;  2OR0 A;  5K3I A;  4M9A A;  3B96 A; 
#chains in the Genus database with same CATH homology
 2EBF X;  1SK6 A;  3VKG A;  4P79 A;  2VF1 A;  2EBH X;  1Y0V A;  4QIC A;  1LVC A;  1XFW A;  3CE2 A;  3C3L A;  4AKH A;  1K90 A;  4FZ4 A;  4FF4 A;  4KS9 A;  3X29 A;  4AI6 A;  2GBB A;  2PO4 A;  3Q0A A;  1PK0 A;  2LFW A;  3N0R A;  4KSA A;  1XFV A;  1XFU A;  4F0X A;  1XFZ A;  2FP1 A;  4FF2 A;  4HKR A;  1SC5 A;  3Q22 A;  3C46 A;  4AKI A;  4FF3 A;  4KSF A;  2EC5 A;  3Q24 A;  4AKG A;  4HKS A;  3VKH A;  3KML A;  1S26 A;  5GJV E;  2YGW A;  1XFY A;  1XFX A;  2QR4 A;  4G97 A;  3Q23 A;  2AO2 A;  2FP2 A;  1K8T A;  2F6L A;  3C2P A;  1RP3 A;  2AZE A;  5GJW E;  4FF1 A;  1K93 A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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