4P79A

Crystal structure of mouse claudin-15
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
189
structure length
181
Chain Sequence
SEFMSVAVETFGFFMSALGLLMLGLTLSNSYWRVSTNTIFENLWYSCATDSLGVSNCWDFPSMLALSGYVQGCRALMITAILLGFLGLFLGMVGLRATNVGNMDLSKKAKLLAIAGTLHILAGACGMVAISWYAVNITTDFFNPLYAGTKYELGPALYLGWSASLLSILGGICVFSTAAAS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell adhesion
molecule keywords Claudin-15
publication title Crystal structure of a claudin provides insight into the architecture of tight junctions.
pubmed doi rcsb
source organism Mus musculus
total genus 59
structure length 181
sequence length 189
ec nomenclature
pdb deposition date 2014-03-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00822 PMP22_Claudin PMP-22/EMP/MP20/Claudin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.140.150 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A; domain 3 4p79A00
3X29A 5GJVE 5GJWE 4P79A
chains in the Genus database with same CATH superfamily
4FF4A 1XFWA 1U8VA 3D9GA 1R3BA 4H85A 4F0XA 2CX9A 2RFQA 3B96A 5B5VA 3MKHA 3SCEA 1GJVA 2QR4A 4Q1OA 3EOMA 1K8TA 2F6LA 3OIBA 4U83A 5B5WA 4X28C 2Z1QA 3VKGA 4Q0TA 3M9VA 1IVHA 2Q8IA 1EGCA 2FP1A 2AZEA 4X28A 2EBHX 2AO2A 2Q8FA 1T9GA 3FCJA 1SC5A 2DVLA 2OR0A 3II9A 4OO2A 3D9FA 4MPNA 5M4NA 2BTZA 2CJ8A 3LGQA 2Q8GA 1XFUA 1LVCA 2IX6A 1UDYA 2BU2A 4M9AA 4N5FA 4HR3A 4DZYA 4Q5CA 2OT4A 3BNJA 2EBFX 3SXQA 4ZYJA 3AFFA 4E02A 2YYLA 3D9EA 1RP3A 1QDBA 2JIFA 3TZ0A 2XS1A 4O5MA 4MP7A 1RJ4A 5K3GA 4JEKA 1EGEA 1X8ZA 3LG1A 2ZKJA 1K93A 1RX0A 4L3XA 5K3JA 5K3IA 4G5EA 4W9UA 3BNHA 3GNCA 3Q24A 2EBAA 3SWOA 3UU9A 2YGWA 3MDDA 2D29A 4L1FA 1XFVA 2JBRA 1EGDA 2A1TA 2C0UA 2E80A 1OAHA 2CJ4A 4KS9A 2RF7A 3MMOA 3SF6A 1FS7A 3X0YA 5M4PA 3VKHA 4Q17A 3N0RA 2OJQA 2VF1A 2VIGA 4HKSA 4LQSB 2XQRB 3F29A 4L38A 1JM6A 4KSFA 1JQIA 1RJ1A 2BU8A 4J1VA 2XS8A 2CJ7A 4V25A 1GKXA 1W07A 1SK6A 2YYMA 4IRNA 3L1TA 5GJWE 3MPIA 4V26A 4FF2A 3TORA 3TZ4A 2CJ5A 2Q8HA 2WBIA 4XVXA 3NF4A 4FZ4A 4KSAA 3TZ5A 1XFXA 1XFZA 3AFEA 2HJNA 3S7WA 2RDZA 2ZDXA 4H81A 5M4KA 3D1IA 1Y0VA 1SIRA 2FONA 2R03A 1IS2A 2PO4A 2CJ6A 3MPJA 3VADA 3CRLA 1X91A 4LQQB 2YYKA 3OWAA 2JBTA 3BNGA 4Q5BA 1UKWA 3EONA 1GU6A 3GM6A 4P13A 3FO3A 4H7QA 4WJYA 4FF3A 3OWMA 2UXWA 4RM7A 1XG2B 3BNFA 3X0XA 1FS9A 2GBBA 2YYGA 3R7KA 3C46A 2E81A 5BRMA 4AKGA 1Y8PA 2ZDYA 3CE2A 1SIQA 4L3ZA 5M4MA 4Q4UA 3Q23A 4AI6A 4E01A 3P4TA 2J7AA 4AKIA 3UBRA 2JBSA 4JIZA 2BU6A 2DDHA 3GQTA 3D6BA 1X90A 1GKZA 4DOYA 5B6BA 4FF1A 1Y8NA 4P79A 2LFWA 3MDEA 4MPCA 2R02A 2ZAFA 2BU5A 2EC5A 5BRKA 3PFDA 4IV6A 1WS9A 5J6AA 3RKHA 3Q0AA 3C3LA 1PI1A 2R05A 4ZXVA 5GJVE 3KMLA 5J71A 4QICA 3X29A 2YYJA 1S26A 2ZO5A 1PK0A 2FP2A 2BU7A 3MXLA 1Y8OA 4G97A 4KTOA 3CRKA 1XFYA 2OEXA 2R0MA 3TZ2A 4E00A 1FS8A 1K90A 1R2JA 2C12A 3D2RA 3Q22A 4AKHA 4NXLA 2REHA 4MPEA 2IX5A 4L3YA 4KCFA 3TTBA 3C2PA 2PNRA 3D9DA 4MP2A 1BUCA 2E0AA 2R0NA 4JIOA 2PG0A 3HWCA 2YYIA 4HKRA 5K3HA 2VR0A 2OEVA
chains in the Genus database with same CATH topology
4FF4A 1XFWA 4AKIA 4F0XA 4FF1A 1XFXA 1XFZA 4P79A 2QR4A 2LFWA 1K8TA 3Q24A 2F6LA 3VKGA 1Y0VA 2EC5A 2YGWA 3Q0AA 3C3LA 1XFVA 2AZEA 2FP1A 2PO4A 2EBHX 3KMLA 5GJVE 4QICA 2AO2A 3X29A 4KS9A 1S26A 1SC5A 1PK0A 2FP2A 3VKHA 4G97A 3N0RA 2VF1A 4HKSA 1XFYA 4AKHA 1K90A 1XFUA 1LVCA 4KSFA 3Q22A 4FF3A 2EBFX 3C2PA 1RP3A 1SK6A 2GBBA 5GJWE 4FF2A 3C46A 4AKGA 3CE2A 4HKRA 3Q23A 4FZ4A 4AI6A 1K93A 4KSAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3X29 A;  5GJV E;  5GJW E;  4P79 A; 
#chains in the Genus database with same CATH topology
 4FF4 A;  1XFW A;  1U8V A;  3D9G A;  1R3B A;  4H85 A;  4F0X A;  2CX9 A;  2RFQ A;  3B96 A;  5B5V A;  3MKH A;  3SCE A;  1GJV A;  2QR4 A;  4Q1O A;  3EOM A;  1K8T A;  2F6L A;  3OIB A;  4U83 A;  5B5W A;  4X28 C;  2Z1Q A;  3VKG A;  4Q0T A;  3M9V A;  1IVH A;  2Q8I A;  1EGC A;  2FP1 A;  2AZE A;  4X28 A;  2EBH X;  2AO2 A;  2Q8F A;  1T9G A;  3FCJ A;  1SC5 A;  2DVL A;  2OR0 A;  3II9 A;  4OO2 A;  3D9F A;  4MPN A;  5M4N A;  2BTZ A;  2CJ8 A;  3LGQ A;  2Q8G A;  1XFU A;  1LVC A;  2IX6 A;  1UDY A;  2BU2 A;  4M9A A;  4N5F A;  4HR3 A;  4DZY A;  4Q5C A;  2OT4 A;  3BNJ A;  2EBF X;  3SXQ A;  4ZYJ A;  3AFF A;  4E02 A;  2YYL A;  3D9E A;  1RP3 A;  1QDB A;  2JIF A;  3TZ0 A;  2XS1 A;  4O5M A;  4MP7 A;  1RJ4 A;  5K3G A;  4JEK A;  1EGE A;  1X8Z A;  3LG1 A;  2ZKJ A;  1K93 A;  1RX0 A;  4L3X A;  5K3J A;  5K3I A;  4G5E A;  4W9U A;  3BNH A;  3GNC A;  3Q24 A;  2EBA A;  3SWO A;  3UU9 A;  2YGW A;  3MDD A;  2D29 A;  4L1F A;  1XFV A;  2JBR A;  1EGD A;  2A1T A;  2C0U A;  2E80 A;  1OAH A;  2CJ4 A;  4KS9 A;  2RF7 A;  3MMO A;  3SF6 A;  1FS7 A;  3X0Y A;  5M4P A;  3VKH A;  4Q17 A;  3N0R A;  2OJQ A;  2VF1 A;  2VIG A;  4HKS A;  4LQS B;  2XQR B;  3F29 A;  4L38 A;  1JM6 A;  4KSF A;  1JQI A;  1RJ1 A;  2BU8 A;  4J1V A;  2XS8 A;  2CJ7 A;  4V25 A;  1GKX A;  1W07 A;  1SK6 A;  2YYM A;  4IRN A;  3L1T A;  5GJW E;  3MPI A;  4V26 A;  4FF2 A;  3TOR A;  3TZ4 A;  2CJ5 A;  2Q8H A;  2WBI A;  4XVX A;  3NF4 A;  4FZ4 A;  4KSA A;  3TZ5 A;  1XFX A;  1XFZ A;  3AFE A;  2HJN A;  3S7W A;  2RDZ A;  2ZDX A;  4H81 A;  5M4K A;  3D1I A;  1Y0V A;  1SIR A;  2FON A;  2R03 A;  1IS2 A;  2PO4 A;  2CJ6 A;  3MPJ A;  3VAD A;  3CRL A;  1X91 A;  4LQQ B;  2YYK A;  3OWA A;  2JBT A;  3BNG A;  4Q5B A;  1UKW A;  3EON A;  1GU6 A;  3GM6 A;  4P13 A;  3FO3 A;  4H7Q A;  4WJY A;  4FF3 A;  3OWM A;  2UXW A;  4RM7 A;  1XG2 B;  3BNF A;  3X0X A;  1FS9 A;  2GBB A;  2YYG A;  3R7K A;  3C46 A;  2E81 A;  5BRM A;  4AKG A;  1Y8P A;  2ZDY A;  3CE2 A;  1SIQ A;  4L3Z A;  5M4M A;  4Q4U A;  3Q23 A;  4AI6 A;  4E01 A;  3P4T A;  2J7A A;  4AKI A;  3UBR A;  2JBS A;  4JIZ A;  2BU6 A;  2DDH A;  3GQT A;  3D6B A;  1X90 A;  1GKZ A;  4DOY A;  5B6B A;  4FF1 A;  1Y8N A;  4P79 A;  2LFW A;  3MDE A;  4MPC A;  2R02 A;  2ZAF A;  2BU5 A;  2EC5 A;  5BRK A;  3PFD A;  4IV6 A;  1WS9 A;  5J6A A;  3RKH A;  3Q0A A;  3C3L A;  1PI1 A;  2R05 A;  4ZXV A;  5GJV E;  3KML A;  5J71 A;  4QIC A;  3X29 A;  2YYJ A;  1S26 A;  2ZO5 A;  1PK0 A;  2FP2 A;  2BU7 A;  3MXL A;  1Y8O A;  4G97 A;  4KTO A;  3CRK A;  1XFY A;  2OEX A;  2R0M A;  3TZ2 A;  4E00 A;  1FS8 A;  1K90 A;  1R2J A;  2C12 A;  3D2R A;  3Q22 A;  4AKH A;  4NXL A;  2REH A;  4MPE A;  2IX5 A;  4L3Y A;  4KCF A;  3TTB A;  3C2P A;  2PNR A;  3D9D A;  4MP2 A;  1BUC A;  2E0A A;  2R0N A;  4JIO A;  2PG0 A;  3HWC A;  2YYI A;  4HKR A;  5K3H A;  2VR0 A;  2OEV A; 
#chains in the Genus database with same CATH homology
 4FF4 A;  1XFW A;  4AKI A;  4F0X A;  4FF1 A;  1XFX A;  1XFZ A;  4P79 A;  2QR4 A;  2LFW A;  1K8T A;  3Q24 A;  2F6L A;  3VKG A;  1Y0V A;  2EC5 A;  2YGW A;  3Q0A A;  3C3L A;  1XFV A;  2AZE A;  2FP1 A;  2PO4 A;  2EBH X;  3KML A;  5GJV E;  4QIC A;  2AO2 A;  3X29 A;  4KS9 A;  1S26 A;  1SC5 A;  1PK0 A;  2FP2 A;  3VKH A;  4G97 A;  3N0R A;  2VF1 A;  4HKS A;  1XFY A;  4AKH A;  1K90 A;  1XFU A;  1LVC A;  4KSF A;  3Q22 A;  4FF3 A;  2EBF X;  3C2P A;  1RP3 A;  1SK6 A;  2GBB A;  5GJW E;  4FF2 A;  3C46 A;  4AKG A;  3CE2 A;  4HKR A;  3Q23 A;  4FZ4 A;  4AI6 A;  1K93 A;  4KSA A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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