2VIGA

Crystal structure of human short-chain acyl coa dehydrogenase
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
379
structure length
379
Chain Sequence
LPETHQMLLQTCRDFAEKELFPIAAQVDKEHLFPAAQVKKMGGLGLLAMDVPEELGGAGLDYLAYAIAMEEISRGCASTGVIMSVNNSLYLGPILKFGSKEQKQAWVTPFTSGDKIGCFALSEPGNGSDAGAASTTARAEGDSWVLNGTKAWITNAWEASAAVVFASTDRALQNKSISAFLVPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSILGEPGMGFKIAMQTLDMGRIGIASQALGIAQTALDCAVNYAENRMAFGAPLTKLQVIQFKLADMALALESARLLTWRAAMLKDNKKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERHYRDARITEIYEGTSEIQRLVIAGHLLRSYRS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
molecule keywords SHORT-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE,
publication title Crystal Structure of Human Short-Chain Acyl Coa Dehydrogenase
rcsb
source organism Homo sapiens
total genus 141
structure length 379
sequence length 379
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 1.3.8.1: Short-chain acyl-CoA dehydrogenase.
pdb deposition date 2007-11-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 2vigA01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 2vigA03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 2vigA02
4X28C 1FS9A 3LGQA 4Q17A 3L1TA 3EOMA 3MXLA 1R2JA 2JIFA 2YYIA 3BNFA 3GNCA 2Z1QA 3EONA 2E81A 3II9A 3D9FA 3MPJA 1JQIA 3M9VA 1U8VA 2IX6A 4U83A 1UKWA 1QDBA 4L1FA 5K3IA 2R0MA 4DOYA 2C12A 2R0NA 3R7KA 4Q1OA 2A1TA 3HWCA 3TORA 2J7AA 4RM7A 4IV6A 1SIQA 3FCJA 1T9GA 2PG0A 2RFQA 4KTOA 3SWOA 2RDZA 1IS2A 2VR0A 1W07A 1SIRA 2YYJA 3UU9A 4KCFA 3RKHA 4X28A 3D6BA 4XVXA 3OWMA 3AFFA 2CX9A 3X0XA 2WBIA 2JBRA 3F29A 1BUCA 2YYGA 2FONA 4P13A 2EBAA 3P4TA 1EGDA 2OR0A 3OWAA 2IX5A 2YYLA 2C0UA 1FS8A 1IVHA 3X0YA 4M9AA 3MDEA 3UBRA 4W9UA 2ZO5A 3MDDA 3LG1A 4O5MA 2JBSA 3SXQA 3S7WA 4OO2A 1WS9A 3BNJA 4L3ZA 5K3JA 3MPIA 3NF4A 2OT4A 1OAHA 3D9EA 1EGCA 3OIBA 4ZXVA 2JBTA 2REHA 4Q5CA 4HR3A 4WJYA 2RF7A 1RX0A 4N5FA 2YYMA 3AFEA 4Q5BA 3MMOA 4L38A 5K3HA 4IRNA 2YYKA 5K3GA 3D9GA 4L3XA 4G5EA 4ZYJA 3B96A 3FO3A 3SF6A 3SCEA 2VIGA 3PFDA 4L3YA 3TTBA 4Q4UA 2DVLA 1EGEA 4Q0TA 3D9DA 4JEKA 4NXLA 1FS7A 2E80A 3BNGA 2DDHA 2ZAFA 1GU6A 3MKHA 2D29A 1UDYA 3BNHA 3D1IA 3GQTA 2UXWA 3GM6A
chains in the Genus database with same CATH superfamily
2OEXA 3VKGA 1XFVA 4X28C 1Y8PA 4KSFA 2FP1A 4MP2A 1FS9A 3LGQA 4AKIA 4Q17A 5B5VA 3L1TA 3EOMA 1RJ4A 3MXLA 2CJ6A 4E01A 4E02A 1R2JA 1R3BA 5M4NA 2JIFA 1S26A 2YYIA 3GNCA 2Z1QA 3BNFA 4FF2A 3EONA 2E81A 3II9A 3D9FA 1GJVA 2BTZA 1XG2B 3MPJA 1JQIA 2ZDYA 3M9VA 1U8VA 4MP7A 1RJ1A 2IX6A 1PK0A 4U83A 1UKWA 1QDBA 2R03A 4L1FA 5K3IA 2R0MA 4DOYA 1K90A 3X29A 2EBHX 2CJ4A 2C12A 5GJVE 2R0NA 3R7KA 1RP3A 4J1VA 4Q1OA 4G97A 4P79A 2A1TA 3HWCA 3TORA 2J7AA 3TZ5A 4RM7A 1X91A 2BU8A 4IV6A 2YGWA 2GBBA 1SIQA 3KMLA 3TZ2A 4DZYA 3FCJA 3U33A 1T9GA 2PG0A 2RFQA 2QR4A 4KTOA 3SWOA 3DJLA 2RDZA 1IS2A 2EBFX 2HJNA 2VR0A 4JIZA 1W07A 1SIRA 5GJWE 4LQQB 2BU2A 2YYJA 3UU9A 4KCFA 3RKHA 4X28A 3D6BA 4XVXA 2R05A 3Q23A 3C46A 3OWMA 3AFFA 5B5WA 2CX9A 3C2PA 2VF1A 3X0XA 2WBIA 2JBRA 2R02A 2ZKJA 3F29A 4FF4A 1SC5A 4AI6A 1BUCA 2YYGA 4AKGA 2EC5A 2Q8FA 2FONA 4P13A 2EBAA 3P4TA 1Y0VA 1EGDA 1PI1A 2XS8A 2Q8IA 2OR0A 4MPNA 2CJ7A 3OWAA 2IX5A 2CJ8A 2BU5A 2C0UA 2YYLA 5M4MA 1FS8A 4AKHA 2Q8HA 2PNRA 1IVHA 3X0YA 2PO4A 4JIOA 4M9AA 1Y8NA 1GKXA 3MDEA 3UBRA 4W9UA 4KSAA 1LVCA 1GKZA 2ZO5A 3MDDA 5B6BA 1XFXA 4V25A 3LG1A 4O5MA 2JBSA 2AO2A 4MPEA 3VKHA 1Y8OA 3SXQA 3S7WA 2OJQA 4OO2A 1WS9A 3BNJA 1XFUA 4KS9A 5M4KA 4L3ZA 2FP2A 3C3LA 5K3JA 3MPIA 3NF4A 2OT4A 5BRKA 1OAHA 3D9EA 1EGCA 3OIBA 4ZXVA 2ZDXA 3CE2A 3N0RA 4HKRA 2JBTA 4E00A 4H7QA 5M4PA 2REHA 4Q5CA 3Q24A 4HR3A 4WJYA 2RF7A 3CRLA 1RX0A 4N5FA 4HKSA 3Q0AA 1K93A 4FF1A 2YYMA 4FZ4A 3AFEA 2XQRB 1XFZA 1SK6A 4MPCA 3MMOA 4Q5BA 4L38A 2OEVA 5K3HA 1X90A 4IRNA 1K8TA 2AZEA 4F0XA 2E0AA 5K3GA 2YYKA 3TZ4A 3D9GA 4LQSB 1XFWA 4L3XA 4G5EA 4ZYJA 1JM6A 3B96A 3FO3A 3SF6A 2LFWA 3CRKA 2VIGA 3SCEA 3PFDA 5J71A 4L3YA 3Q22A 3TTBA 4Q4UA 2DVLA 5EZ3A 2BU7A 1X8ZA 4FF3A 1EGEA 1XFYA 3TZ0A 4Q0TA 2BU6A 3D9DA 4JEKA 4NXLA 1FS7A 2E80A 3BNGA 4QICA 5BRMA 2Q8GA 2DDHA 2XS1A 2ZAFA 1GU6A 2F6LA 3MKHA 5J6AA 2D29A 3VADA 1UDYA 2CJ5A 4H85A 3BNHA 3D1IA 4H81A 3D2RA 3GQTA 2UXWA 3GM6A 4V26A
chains in the Genus database with same CATH topology
4X28C 1FS9A 3LGQA 4Q17A 3L1TA 3EOMA 3MXLA 1R2JA 2JIFA 2YYIA 3BNFA 3GNCA 2Z1QA 3EONA 2E81A 3II9A 3D9FA 3MPJA 1JQIA 3M9VA 1U8VA 2IX6A 4U83A 1UKWA 1QDBA 4L1FA 5K3IA 2R0MA 4DOYA 2C12A 2R0NA 3R7KA 4Q1OA 2A1TA 3HWCA 3TORA 2J7AA 4RM7A 4IV6A 1SIQA 3FCJA 1T9GA 2PG0A 2RFQA 4KTOA 3SWOA 2RDZA 1IS2A 2VR0A 1W07A 1SIRA 2YYJA 3UU9A 4KCFA 3RKHA 4X28A 3D6BA 4XVXA 3OWMA 3AFFA 2CX9A 3X0XA 2WBIA 2JBRA 3F29A 1BUCA 2YYGA 2FONA 4P13A 2EBAA 3P4TA 1EGDA 2OR0A 3OWAA 2IX5A 2YYLA 2C0UA 1FS8A 1IVHA 3X0YA 4M9AA 3MDEA 3UBRA 4W9UA 2ZO5A 3MDDA 3LG1A 4O5MA 2JBSA 3SXQA 3S7WA 4OO2A 1WS9A 3BNJA 4L3ZA 5K3JA 3MPIA 3NF4A 2OT4A 1OAHA 3D9EA 1EGCA 3OIBA 4ZXVA 2JBTA 2REHA 4Q5CA 4HR3A 4WJYA 2RF7A 1RX0A 4N5FA 2YYMA 3AFEA 4Q5BA 3MMOA 4L38A 5K3HA 4IRNA 2YYKA 5K3GA 3D9GA 4L3XA 4G5EA 4ZYJA 3B96A 3FO3A 3SF6A 3SCEA 2VIGA 3PFDA 4L3YA 3TTBA 4Q4UA 2DVLA 1EGEA 4Q0TA 3D9DA 4JEKA 4NXLA 1FS7A 2E80A 3BNGA 2DDHA 2ZAFA 1GU6A 3MKHA 2D29A 1UDYA 3BNHA 3D1IA 3GQTA 2UXWA 3GM6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4X28 C;  1FS9 A;  3LGQ A;  4Q17 A;  3L1T A;  3EOM A;  3MXL A;  1R2J A;  2JIF A;  2YYI A;  3BNF A;  3GNC A;  2Z1Q A;  3EON A;  2E81 A;  3II9 A;  3D9F A;  3MPJ A;  1JQI A;  3M9V A;  1U8V A;  2IX6 A;  4U83 A;  1UKW A;  1QDB A;  4L1F A;  5K3I A;  2R0M A;  4DOY A;  2C12 A;  2R0N A;  3R7K A;  4Q1O A;  2A1T A;  3HWC A;  3TOR A;  2J7A A;  4RM7 A;  4IV6 A;  1SIQ A;  3FCJ A;  1T9G A;  2PG0 A;  2RFQ A;  4KTO A;  3SWO A;  2RDZ A;  1IS2 A;  2VR0 A;  1W07 A;  1SIR A;  2YYJ A;  3UU9 A;  4KCF A;  3RKH A;  4X28 A;  3D6B A;  4XVX A;  3OWM A;  3AFF A;  2CX9 A;  3X0X A;  2WBI A;  2JBR A;  3F29 A;  1BUC A;  2YYG A;  2FON A;  4P13 A;  2EBA A;  3P4T A;  1EGD A;  2OR0 A;  3OWA A;  2IX5 A;  2YYL A;  2C0U A;  1FS8 A;  1IVH A;  3X0Y A;  4M9A A;  3MDE A;  3UBR A;  4W9U A;  2ZO5 A;  3MDD A;  3LG1 A;  4O5M A;  2JBS A;  3SXQ A;  3S7W A;  4OO2 A;  1WS9 A;  3BNJ A;  4L3Z A;  5K3J A;  3MPI A;  3NF4 A;  2OT4 A;  1OAH A;  3D9E A;  1EGC A;  3OIB A;  4ZXV A;  2JBT A;  2REH A;  4Q5C A;  4HR3 A;  4WJY A;  2RF7 A;  1RX0 A;  4N5F A;  2YYM A;  3AFE A;  4Q5B A;  3MMO A;  4L38 A;  5K3H A;  4IRN A;  2YYK A;  5K3G A;  3D9G A;  4L3X A;  4G5E A;  4ZYJ A;  3B96 A;  3FO3 A;  3SF6 A;  3SCE A;  2VIG A;  3PFD A;  4L3Y A;  3TTB A;  4Q4U A;  2DVL A;  1EGE A;  4Q0T A;  3D9D A;  4JEK A;  4NXL A;  1FS7 A;  2E80 A;  3BNG A;  2DDH A;  2ZAF A;  1GU6 A;  3MKH A;  2D29 A;  1UDY A;  3BNH A;  3D1I A;  3GQT A;  2UXW A;  3GM6 A; 
#chains in the Genus database with same CATH topology
 2OEX A;  3VKG A;  1XFV A;  4X28 C;  1Y8P A;  4KSF A;  2FP1 A;  4MP2 A;  1FS9 A;  3LGQ A;  4AKI A;  4Q17 A;  5B5V A;  3L1T A;  3EOM A;  1RJ4 A;  3MXL A;  2CJ6 A;  4E01 A;  4E02 A;  1R2J A;  1R3B A;  5M4N A;  2JIF A;  1S26 A;  2YYI A;  3GNC A;  2Z1Q A;  3BNF A;  4FF2 A;  3EON A;  2E81 A;  3II9 A;  3D9F A;  1GJV A;  2BTZ A;  1XG2 B;  3MPJ A;  1JQI A;  2ZDY A;  3M9V A;  1U8V A;  4MP7 A;  1RJ1 A;  2IX6 A;  1PK0 A;  4U83 A;  1UKW A;  1QDB A;  2R03 A;  4L1F A;  5K3I A;  2R0M A;  4DOY A;  1K90 A;  3X29 A;  2EBH X;  2CJ4 A;  2C12 A;  5GJV E;  2R0N A;  3R7K A;  1RP3 A;  4J1V A;  4Q1O A;  4G97 A;  4P79 A;  2A1T A;  3HWC A;  3TOR A;  2J7A A;  3TZ5 A;  4RM7 A;  1X91 A;  2BU8 A;  4IV6 A;  2YGW A;  2GBB A;  1SIQ A;  3KML A;  3TZ2 A;  4DZY A;  3FCJ A;  3U33 A;  1T9G A;  2PG0 A;  2RFQ A;  2QR4 A;  4KTO A;  3SWO A;  3DJL A;  2RDZ A;  1IS2 A;  2EBF X;  2HJN A;  2VR0 A;  4JIZ A;  1W07 A;  1SIR A;  5GJW E;  4LQQ B;  2BU2 A;  2YYJ A;  3UU9 A;  4KCF A;  3RKH A;  4X28 A;  3D6B A;  4XVX A;  2R05 A;  3Q23 A;  3C46 A;  3OWM A;  3AFF A;  5B5W A;  2CX9 A;  3C2P A;  2VF1 A;  3X0X A;  2WBI A;  2JBR A;  2R02 A;  2ZKJ A;  3F29 A;  4FF4 A;  1SC5 A;  4AI6 A;  1BUC A;  2YYG A;  4AKG A;  2EC5 A;  2Q8F A;  2FON A;  4P13 A;  2EBA A;  3P4T A;  1Y0V A;  1EGD A;  1PI1 A;  2XS8 A;  2Q8I A;  2OR0 A;  4MPN A;  2CJ7 A;  3OWA A;  2IX5 A;  2CJ8 A;  2BU5 A;  2C0U A;  2YYL A;  5M4M A;  1FS8 A;  4AKH A;  2Q8H A;  2PNR A;  1IVH A;  3X0Y A;  2PO4 A;  4JIO A;  4M9A A;  1Y8N A;  1GKX A;  3MDE A;  3UBR A;  4W9U A;  4KSA A;  1LVC A;  1GKZ A;  2ZO5 A;  3MDD A;  5B6B A;  1XFX A;  4V25 A;  3LG1 A;  4O5M A;  2JBS A;  2AO2 A;  4MPE A;  3VKH A;  1Y8O A;  3SXQ A;  3S7W A;  2OJQ A;  4OO2 A;  1WS9 A;  3BNJ A;  1XFU A;  4KS9 A;  5M4K A;  4L3Z A;  2FP2 A;  3C3L A;  5K3J A;  3MPI A;  3NF4 A;  2OT4 A;  5BRK A;  1OAH A;  3D9E A;  1EGC A;  3OIB A;  4ZXV A;  2ZDX A;  3CE2 A;  3N0R A;  4HKR A;  2JBT A;  4E00 A;  4H7Q A;  5M4P A;  2REH A;  4Q5C A;  3Q24 A;  4HR3 A;  4WJY A;  2RF7 A;  3CRL A;  1RX0 A;  4N5F A;  4HKS A;  3Q0A A;  1K93 A;  4FF1 A;  2YYM A;  4FZ4 A;  3AFE A;  2XQR B;  1XFZ A;  1SK6 A;  4MPC A;  3MMO A;  4Q5B A;  4L38 A;  2OEV A;  5K3H A;  1X90 A;  4IRN A;  1K8T A;  2AZE A;  4F0X A;  2E0A A;  5K3G A;  2YYK A;  3TZ4 A;  3D9G A;  4LQS B;  1XFW A;  4L3X A;  4G5E A;  4ZYJ A;  1JM6 A;  3B96 A;  3FO3 A;  3SF6 A;  2LFW A;  3CRK A;  2VIG A;  3SCE A;  3PFD A;  5J71 A;  4L3Y A;  3Q22 A;  3TTB A;  4Q4U A;  2DVL A;  5EZ3 A;  2BU7 A;  1X8Z A;  4FF3 A;  1EGE A;  1XFY A;  3TZ0 A;  4Q0T A;  2BU6 A;  3D9D A;  4JEK A;  4NXL A;  1FS7 A;  2E80 A;  3BNG A;  4QIC A;  5BRM A;  2Q8G A;  2DDH A;  2XS1 A;  2ZAF A;  1GU6 A;  2F6L A;  3MKH A;  5J6A A;  2D29 A;  3VAD A;  1UDY A;  2CJ5 A;  4H85 A;  3BNH A;  3D1I A;  4H81 A;  3D2R A;  3GQT A;  2UXW A;  3GM6 A;  4V26 A; 
#chains in the Genus database with same CATH homology
 4X28 C;  1FS9 A;  3LGQ A;  4Q17 A;  3L1T A;  3EOM A;  3MXL A;  1R2J A;  2JIF A;  2YYI A;  3BNF A;  3GNC A;  2Z1Q A;  3EON A;  2E81 A;  3II9 A;  3D9F A;  3MPJ A;  1JQI A;  3M9V A;  1U8V A;  2IX6 A;  4U83 A;  1UKW A;  1QDB A;  4L1F A;  5K3I A;  2R0M A;  4DOY A;  2C12 A;  2R0N A;  3R7K A;  4Q1O A;  2A1T A;  3HWC A;  3TOR A;  2J7A A;  4RM7 A;  4IV6 A;  1SIQ A;  3FCJ A;  1T9G A;  2PG0 A;  2RFQ A;  4KTO A;  3SWO A;  2RDZ A;  1IS2 A;  2VR0 A;  1W07 A;  1SIR A;  2YYJ A;  3UU9 A;  4KCF A;  3RKH A;  4X28 A;  3D6B A;  4XVX A;  3OWM A;  3AFF A;  2CX9 A;  3X0X A;  2WBI A;  2JBR A;  3F29 A;  1BUC A;  2YYG A;  2FON A;  4P13 A;  2EBA A;  3P4T A;  1EGD A;  2OR0 A;  3OWA A;  2IX5 A;  2YYL A;  2C0U A;  1FS8 A;  1IVH A;  3X0Y A;  4M9A A;  3MDE A;  3UBR A;  4W9U A;  2ZO5 A;  3MDD A;  3LG1 A;  4O5M A;  2JBS A;  3SXQ A;  3S7W A;  4OO2 A;  1WS9 A;  3BNJ A;  4L3Z A;  5K3J A;  3MPI A;  3NF4 A;  2OT4 A;  1OAH A;  3D9E A;  1EGC A;  3OIB A;  4ZXV A;  2JBT A;  2REH A;  4Q5C A;  4HR3 A;  4WJY A;  2RF7 A;  1RX0 A;  4N5F A;  2YYM A;  3AFE A;  4Q5B A;  3MMO A;  4L38 A;  5K3H A;  4IRN A;  2YYK A;  5K3G A;  3D9G A;  4L3X A;  4G5E A;  4ZYJ A;  3B96 A;  3FO3 A;  3SF6 A;  3SCE A;  2VIG A;  3PFD A;  4L3Y A;  3TTB A;  4Q4U A;  2DVL A;  1EGE A;  4Q0T A;  3D9D A;  4JEK A;  4NXL A;  1FS7 A;  2E80 A;  3BNG A;  2DDH A;  2ZAF A;  1GU6 A;  3MKH A;  2D29 A;  1UDY A;  3BNH A;  3D1I A;  3GQT A;  2UXW A;  3GM6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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