2VIGA

Crystal structure of human short-chain acyl coa dehydrogenase
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
379
structure length
379
Chain Sequence
LPETHQMLLQTCRDFAEKELFPIAAQVDKEHLFPAAQVKKMGGLGLLAMDVPEELGGAGLDYLAYAIAMEEISRGCASTGVIMSVNNSLYLGPILKFGSKEQKQAWVTPFTSGDKIGCFALSEPGNGSDAGAASTTARAEGDSWVLNGTKAWITNAWEASAAVVFASTDRALQNKSISAFLVPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSILGEPGMGFKIAMQTLDMGRIGIASQALGIAQTALDCAVNYAENRMAFGAPLTKLQVIQFKLADMALALESARLLTWRAAMLKDNKKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERHYRDARITEIYEGTSEIQRLVIAGHLLRSYRS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords SHORT-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE,
publication title Crystal Structure of Human Short-Chain Acyl Coa Dehydrogenase
rcsb
source organism Homo sapiens
molecule tags Oxidoreductase
total genus 141
structure length 379
sequence length 379
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 1.3.8.1: Short-chain acyl-CoA dehydrogenase.
pdb deposition date 2007-11-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 2vigA01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 2vigA03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 2vigA02
2VR0A 3BNFA 4Q5CA 3MPJA 3X0YA 3MKHA 4O5MA 3UBRA 3UU9A 1IS2A 2JBSA 3GQTA 3P4TA 5K3HA 2YYIA 4JEKA 3LG1A 5K3JA 1EGDA 3L1TA 1BUCA 5K3GA 4N5FA 1SIRA 4P13A 2C0UA 3D9GA 3GM6A 2Z1QA 1OAHA 3F29A 3SCEA 4M9AA 4L3YA 2R0MA 2E80A 3R7KA 3SF6A 3SXQA 3GNCA 4W9UA 3MMOA 2R0NA 2EBAA 4RM7A 4G5EA 1UDYA 1GU6A 2ZAFA 2J7AA 3BNGA 2REHA 3B96A 1FS7A 4L3ZA 4IRNA 4HR3A 3AFEA 2FONA 4X28A 3D9FA 2RDZA 4X28C 3OWAA 3X0XA 3SWOA 4ZXVA 1EGCA 3NF4A 4Q5BA 3RKHA 1W07A 1RX0A 3S7WA 3D9DA 4NXLA 3II9A 4KCFA 3BNHA 1WS9A 1UKWA 4U83A 2E81A 1QDBA 3TTBA 2JBTA 2RFQA 1EGEA 2JIFA 2ZO5A 2VIGA 5K3IA 4WJYA 3MDDA 3OIBA 2WBIA 3OWMA 3D6BA 4L1FA 2A1TA 3PFDA 3FCJA 2IX6A 4KTOA 3HWCA 2CX9A 4Q17A 2DDHA 3AFFA 4ZYJA 3LGQA 3D1IA 3MPIA 3D9EA 3EOMA 2D29A 2YYKA 4Q0TA 2DVLA 1FS9A 4L3XA 2YYGA 2JBRA 4OO2A 3MDEA 2YYMA 2YYJA 1U8VA 1R2JA 4Q4UA 4L38A 4XVXA 2RF7A 1JQIA 1T9GA 3MXLA 1FS8A 3TORA 3M9VA 3FO3A 3BNJA 1SIQA 4IV6A 2YYLA 2IX5A 4DOYA 3EONA 2OT4A 1IVHA 2OR0A 4Q1OA 2C12A 2PG0A 2UXWA
chains in the Genus database with same CATH superfamily
4KSFA 1XFZA 1XFWA 2VR0A 3BNFA 3MPJA 3X0YA 3MKHA 4O5MA 1SK6A 4Q5CA 1IS2A 2JBSA 3GQTA 3P4TA 5K3HA 1GJVA 2PNRA 5GJVE 3CRLA 2YYIA 1GKXA 4JEKA 1S26A 3LG1A 5K3JA 1EGDA 1RJ4A 2BU7A 2F6LA 3L1TA 4E01A 3Q22A 3VADA 3C3LA 1BUCA 5K3GA 4FF3A 4N5FA 1SIRA 4P13A 2C0UA 3D9GA 1K8TA 3TZ0A 3GM6A 2Z1QA 1K90A 1OAHA 2LFWA 4V26A 3F29A 3SCEA 4M9AA 4AKIA 4L3YA 2R0MA 4MP2A 4E02A 2AZEA 1PI1A 5B5WA 2E80A 1X8ZA 3R7KA 3SF6A 3SXQA 1XFYA 3GNCA 4W9UA 5M4MA 3Q24A 3MMOA 1XFVA 2R0NA 2EBAA 4RM7A 2PO4A 4G5EA 4LQQB 2BU2A 1UDYA 1GU6A 2ZAFA 2J7AA 3BNGA 2REHA 2EBHX 3B96A 3VKGA 2XS1A 2CJ5A 1FS7A 5B6BA 4L3ZA 4IRNA 1XFXA 4HR3A 4FZ4A 3TZ5A 3AFEA 5B5VA 2FONA 5J71A 1XG2B 4X28A 3D9FA 2Q8GA 2RDZA 2VF1A 4X28C 1XFUA 2FP2A 3OWAA 2ZDYA 1K93A 4H85A 3X0XA 3SWOA 4ZXVA 1EGCA 4KSAA 3NF4A 4Q5BA 3RKHA 1W07A 2ZKJA 4QICA 5BRMA 1RX0A 4G97A 3S7WA 3D9DA 4NXLA 3TZ4A 3X29A 3II9A 4KCFA 3BNHA 2Q8HA 4V25A 1WS9A 3UU9A 4FF1A 4AKHA 1UKWA 3VKHA 4U83A 2ZDXA 2E81A 2AO2A 1QDBA 2Q8IA 1GKZA 4H81A 3TTBA 2JBTA 2R03A 2CJ6A 2OJQA 5GJWE 2RFQA 1EGEA 2JIFA 2GBBA 2ZO5A 3C46A 2VIGA 5K3IA 1JM6A 4WJYA 3MDDA 3OIBA 1LVCA 4LQSB 1SC5A 2WBIA 2OEVA 3OWMA 4H7QA 4MPCA 4FF4A 2YGWA 2OEXA 4JIOA 3D6BA 4L1FA 2A1TA 1R3BA 3PFDA 1X90A 2BU6A 3CE2A 3N0RA 3FCJA 3DJLA 2QR4A 2IX6A 2HJNA 4KTOA 3HWCA 3UBRA 2CX9A 3D2RA 2DDHA 4Q17A 3Q23A 2BTZA 3AFFA 4ZYJA 3LGQA 3D1IA 3CRKA 3MPIA 3D9EA 2R02A 2E0AA 4AI6A 3EOMA 2EBFX 3Q0AA 2CJ7A 1RP3A 2D29A 1Y8NA 2XS8A 4KS9A 4F0XA 1Y8PA 2YYKA 4Q0TA 2DVLA 1FS9A 4L3XA 2YYGA 4MPNA 2JBRA 1X91A 4OO2A 3MDEA 2YYMA 3TZ2A 2YYJA 2CJ4A 2Q8FA 1U8VA 1R2JA 4HKSA 4Q4UA 3KMLA 4J1VA 4DZYA 2FP1A 5M4NA 4FF2A 5J6AA 5EZ3A 4MPEA 4HKRA 4L38A 4XVXA 2RF7A 1JQIA 1T9GA 3MXLA 1FS8A 2CJ8A 3TORA 4E00A 3M9VA 2XQRB 3FO3A 5BRKA 4P79A 5M4PA 3BNJA 1SIQA 4IV6A 2R05A 2EC5A 5M4KA 1Y0VA 3U33A 1RJ1A 2YYLA 2IX5A 3C2PA 4DOYA 4MP7A 4AKGA 3EONA 1PK0A 1Y8OA 1IVHA 2OR0A 2OT4A 4Q1OA 2C12A 2PG0A 4JIZA 2BU8A 2BU5A 2UXWA
chains in the Genus database with same CATH topology
2VR0A 3BNFA 4Q5CA 3MPJA 3X0YA 3MKHA 4O5MA 3UBRA 3UU9A 1IS2A 2JBSA 3GQTA 3P4TA 5K3HA 2YYIA 4JEKA 3LG1A 5K3JA 1EGDA 3L1TA 1BUCA 5K3GA 4N5FA 1SIRA 4P13A 2C0UA 3D9GA 3GM6A 2Z1QA 1OAHA 3F29A 3SCEA 4M9AA 4L3YA 2R0MA 2E80A 3R7KA 3SF6A 3SXQA 3GNCA 4W9UA 3MMOA 2R0NA 2EBAA 4RM7A 4G5EA 1UDYA 1GU6A 2ZAFA 2J7AA 3BNGA 2REHA 3B96A 1FS7A 4L3ZA 4IRNA 4HR3A 3AFEA 2FONA 4X28A 3D9FA 2RDZA 4X28C 3OWAA 3X0XA 3SWOA 4ZXVA 1EGCA 3NF4A 4Q5BA 3RKHA 1W07A 1RX0A 3S7WA 3D9DA 4NXLA 3II9A 4KCFA 3BNHA 1WS9A 1UKWA 4U83A 2E81A 1QDBA 3TTBA 2JBTA 2RFQA 1EGEA 2JIFA 2ZO5A 2VIGA 5K3IA 4WJYA 3MDDA 3OIBA 2WBIA 3OWMA 3D6BA 4L1FA 2A1TA 3PFDA 3FCJA 2IX6A 4KTOA 3HWCA 2CX9A 4Q17A 2DDHA 3AFFA 4ZYJA 3LGQA 3D1IA 3MPIA 3D9EA 3EOMA 2D29A 2YYKA 4Q0TA 2DVLA 1FS9A 4L3XA 2YYGA 2JBRA 4OO2A 3MDEA 2YYMA 2YYJA 1U8VA 1R2JA 4Q4UA 4L38A 4XVXA 2RF7A 1JQIA 1T9GA 3MXLA 1FS8A 3TORA 3M9VA 3FO3A 3BNJA 1SIQA 4IV6A 2YYLA 2IX5A 4DOYA 3EONA 2OT4A 1IVHA 2OR0A 4Q1OA 2C12A 2PG0A 2UXWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VR0 A;  3BNF A;  4Q5C A;  3MPJ A;  3X0Y A;  3MKH A;  4O5M A;  3UBR A;  3UU9 A;  1IS2 A;  2JBS A;  3GQT A;  3P4T A;  5K3H A;  2YYI A;  4JEK A;  3LG1 A;  5K3J A;  1EGD A;  3L1T A;  1BUC A;  5K3G A;  4N5F A;  1SIR A;  4P13 A;  2C0U A;  3D9G A;  3GM6 A;  2Z1Q A;  1OAH A;  3F29 A;  3SCE A;  4M9A A;  4L3Y A;  2R0M A;  2E80 A;  3R7K A;  3SF6 A;  3SXQ A;  3GNC A;  4W9U A;  3MMO A;  2R0N A;  2EBA A;  4RM7 A;  4G5E A;  1UDY A;  1GU6 A;  2ZAF A;  2J7A A;  3BNG A;  2REH A;  3B96 A;  1FS7 A;  4L3Z A;  4IRN A;  4HR3 A;  3AFE A;  2FON A;  4X28 A;  3D9F A;  2RDZ A;  4X28 C;  3OWA A;  3X0X A;  3SWO A;  4ZXV A;  1EGC A;  3NF4 A;  4Q5B A;  3RKH A;  1W07 A;  1RX0 A;  3S7W A;  3D9D A;  4NXL A;  3II9 A;  4KCF A;  3BNH A;  1WS9 A;  1UKW A;  4U83 A;  2E81 A;  1QDB A;  3TTB A;  2JBT A;  2RFQ A;  1EGE A;  2JIF A;  2ZO5 A;  2VIG A;  5K3I A;  4WJY A;  3MDD A;  3OIB A;  2WBI A;  3OWM A;  3D6B A;  4L1F A;  2A1T A;  3PFD A;  3FCJ A;  2IX6 A;  4KTO A;  3HWC A;  2CX9 A;  4Q17 A;  2DDH A;  3AFF A;  4ZYJ A;  3LGQ A;  3D1I A;  3MPI A;  3D9E A;  3EOM A;  2D29 A;  2YYK A;  4Q0T A;  2DVL A;  1FS9 A;  4L3X A;  2YYG A;  2JBR A;  4OO2 A;  3MDE A;  2YYM A;  2YYJ A;  1U8V A;  1R2J A;  4Q4U A;  4L38 A;  4XVX A;  2RF7 A;  1JQI A;  1T9G A;  3MXL A;  1FS8 A;  3TOR A;  3M9V A;  3FO3 A;  3BNJ A;  1SIQ A;  4IV6 A;  2YYL A;  2IX5 A;  4DOY A;  3EON A;  2OT4 A;  1IVH A;  2OR0 A;  4Q1O A;  2C12 A;  2PG0 A;  2UXW A; 
#chains in the Genus database with same CATH topology
 4KSF A;  1XFZ A;  1XFW A;  2VR0 A;  3BNF A;  3MPJ A;  3X0Y A;  3MKH A;  4O5M A;  1SK6 A;  4Q5C A;  1IS2 A;  2JBS A;  3GQT A;  3P4T A;  5K3H A;  1GJV A;  2PNR A;  5GJV E;  3CRL A;  2YYI A;  1GKX A;  4JEK A;  1S26 A;  3LG1 A;  5K3J A;  1EGD A;  1RJ4 A;  2BU7 A;  2F6L A;  3L1T A;  4E01 A;  3Q22 A;  3VAD A;  3C3L A;  1BUC A;  5K3G A;  4FF3 A;  4N5F A;  1SIR A;  4P13 A;  2C0U A;  3D9G A;  1K8T A;  3TZ0 A;  3GM6 A;  2Z1Q A;  1K90 A;  1OAH A;  2LFW A;  4V26 A;  3F29 A;  3SCE A;  4M9A A;  4AKI A;  4L3Y A;  2R0M A;  4MP2 A;  4E02 A;  2AZE A;  1PI1 A;  5B5W A;  2E80 A;  1X8Z A;  3R7K A;  3SF6 A;  3SXQ A;  1XFY A;  3GNC A;  4W9U A;  5M4M A;  3Q24 A;  3MMO A;  1XFV A;  2R0N A;  2EBA A;  4RM7 A;  2PO4 A;  4G5E A;  4LQQ B;  2BU2 A;  1UDY A;  1GU6 A;  2ZAF A;  2J7A A;  3BNG A;  2REH A;  2EBH X;  3B96 A;  3VKG A;  2XS1 A;  2CJ5 A;  1FS7 A;  5B6B A;  4L3Z A;  4IRN A;  1XFX A;  4HR3 A;  4FZ4 A;  3TZ5 A;  3AFE A;  5B5V A;  2FON A;  5J71 A;  1XG2 B;  4X28 A;  3D9F A;  2Q8G A;  2RDZ A;  2VF1 A;  4X28 C;  1XFU A;  2FP2 A;  3OWA A;  2ZDY A;  1K93 A;  4H85 A;  3X0X A;  3SWO A;  4ZXV A;  1EGC A;  4KSA A;  3NF4 A;  4Q5B A;  3RKH A;  1W07 A;  2ZKJ A;  4QIC A;  5BRM A;  1RX0 A;  4G97 A;  3S7W A;  3D9D A;  4NXL A;  3TZ4 A;  3X29 A;  3II9 A;  4KCF A;  3BNH A;  2Q8H A;  4V25 A;  1WS9 A;  3UU9 A;  4FF1 A;  4AKH A;  1UKW A;  3VKH A;  4U83 A;  2ZDX A;  2E81 A;  2AO2 A;  1QDB A;  2Q8I A;  1GKZ A;  4H81 A;  3TTB A;  2JBT A;  2R03 A;  2CJ6 A;  2OJQ A;  5GJW E;  2RFQ A;  1EGE A;  2JIF A;  2GBB A;  2ZO5 A;  3C46 A;  2VIG A;  5K3I A;  1JM6 A;  4WJY A;  3MDD A;  3OIB A;  1LVC A;  4LQS B;  1SC5 A;  2WBI A;  2OEV A;  3OWM A;  4H7Q A;  4MPC A;  4FF4 A;  2YGW A;  2OEX A;  4JIO A;  3D6B A;  4L1F A;  2A1T A;  1R3B A;  3PFD A;  1X90 A;  2BU6 A;  3CE2 A;  3N0R A;  3FCJ A;  3DJL A;  2QR4 A;  2IX6 A;  2HJN A;  4KTO A;  3HWC A;  3UBR A;  2CX9 A;  3D2R A;  2DDH A;  4Q17 A;  3Q23 A;  2BTZ A;  3AFF A;  4ZYJ A;  3LGQ A;  3D1I A;  3CRK A;  3MPI A;  3D9E A;  2R02 A;  2E0A A;  4AI6 A;  3EOM A;  2EBF X;  3Q0A A;  2CJ7 A;  1RP3 A;  2D29 A;  1Y8N A;  2XS8 A;  4KS9 A;  4F0X A;  1Y8P A;  2YYK A;  4Q0T A;  2DVL A;  1FS9 A;  4L3X A;  2YYG A;  4MPN A;  2JBR A;  1X91 A;  4OO2 A;  3MDE A;  2YYM A;  3TZ2 A;  2YYJ A;  2CJ4 A;  2Q8F A;  1U8V A;  1R2J A;  4HKS A;  4Q4U A;  3KML A;  4J1V A;  4DZY A;  2FP1 A;  5M4N A;  4FF2 A;  5J6A A;  5EZ3 A;  4MPE A;  4HKR A;  4L38 A;  4XVX A;  2RF7 A;  1JQI A;  1T9G A;  3MXL A;  1FS8 A;  2CJ8 A;  3TOR A;  4E00 A;  3M9V A;  2XQR B;  3FO3 A;  5BRK A;  4P79 A;  5M4P A;  3BNJ A;  1SIQ A;  4IV6 A;  2R05 A;  2EC5 A;  5M4K A;  1Y0V A;  3U33 A;  1RJ1 A;  2YYL A;  2IX5 A;  3C2P A;  4DOY A;  4MP7 A;  4AKG A;  3EON A;  1PK0 A;  1Y8O A;  1IVH A;  2OR0 A;  2OT4 A;  4Q1O A;  2C12 A;  2PG0 A;  4JIZ A;  2BU8 A;  2BU5 A;  2UXW A; 
#chains in the Genus database with same CATH homology
 2VR0 A;  3BNF A;  4Q5C A;  3MPJ A;  3X0Y A;  3MKH A;  4O5M A;  3UBR A;  3UU9 A;  1IS2 A;  2JBS A;  3GQT A;  3P4T A;  5K3H A;  2YYI A;  4JEK A;  3LG1 A;  5K3J A;  1EGD A;  3L1T A;  1BUC A;  5K3G A;  4N5F A;  1SIR A;  4P13 A;  2C0U A;  3D9G A;  3GM6 A;  2Z1Q A;  1OAH A;  3F29 A;  3SCE A;  4M9A A;  4L3Y A;  2R0M A;  2E80 A;  3R7K A;  3SF6 A;  3SXQ A;  3GNC A;  4W9U A;  3MMO A;  2R0N A;  2EBA A;  4RM7 A;  4G5E A;  1UDY A;  1GU6 A;  2ZAF A;  2J7A A;  3BNG A;  2REH A;  3B96 A;  1FS7 A;  4L3Z A;  4IRN A;  4HR3 A;  3AFE A;  2FON A;  4X28 A;  3D9F A;  2RDZ A;  4X28 C;  3OWA A;  3X0X A;  3SWO A;  4ZXV A;  1EGC A;  3NF4 A;  4Q5B A;  3RKH A;  1W07 A;  1RX0 A;  3S7W A;  3D9D A;  4NXL A;  3II9 A;  4KCF A;  3BNH A;  1WS9 A;  1UKW A;  4U83 A;  2E81 A;  1QDB A;  3TTB A;  2JBT A;  2RFQ A;  1EGE A;  2JIF A;  2ZO5 A;  2VIG A;  5K3I A;  4WJY A;  3MDD A;  3OIB A;  2WBI A;  3OWM A;  3D6B A;  4L1F A;  2A1T A;  3PFD A;  3FCJ A;  2IX6 A;  4KTO A;  3HWC A;  2CX9 A;  4Q17 A;  2DDH A;  3AFF A;  4ZYJ A;  3LGQ A;  3D1I A;  3MPI A;  3D9E A;  3EOM A;  2D29 A;  2YYK A;  4Q0T A;  2DVL A;  1FS9 A;  4L3X A;  2YYG A;  2JBR A;  4OO2 A;  3MDE A;  2YYM A;  2YYJ A;  1U8V A;  1R2J A;  4Q4U A;  4L38 A;  4XVX A;  2RF7 A;  1JQI A;  1T9G A;  3MXL A;  1FS8 A;  3TOR A;  3M9V A;  3FO3 A;  3BNJ A;  1SIQ A;  4IV6 A;  2YYL A;  2IX5 A;  4DOY A;  3EON A;  2OT4 A;  1IVH A;  2OR0 A;  4Q1O A;  2C12 A;  2PG0 A;  2UXW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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