2RFQA

Crystal structure of 3-hsa hydroxylase from rhodococcus sp. rha1
Total Genus 149
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
149
sequence length
388
structure length
388
Chain Sequence
HDSHEVMQRLDALLPTLRERAQETEDLRRIPDDSMKALQETGFFRLLQPEQWGGYQADPVLFYSAVRKIASACGSTGWVSSIIGVHNWHLALFSQQAQEDVWGNDTDVRISSSYAPMGAGQVVDGGYTVNGAWAWSSGCDHASWAVLGGPVIKDGRPVDFVSFLIPREDYRIDDVWNVVGLRGTGSNTVVVEDVFVPTHRVLSFKAMSNLTAPGLERNTAPVYKMPWGTIHPTTISAPIVGMAYGAYDAHVEHQGKRVRAAFAGEKAKDDPFAKVRIAEASSDIDAAWRQLSGNVADEYALLVAGEEVPFELRLRARRDQVRATGRAISSIDKLFESSGATALANGTPLQRFWRDAHAGRVHAANDPERAYVMYGTGEFGLPITDTMV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
molecule keywords 3-HSA hydroxylase, oxygenase
publication title Crystal structure of 3-HSA hydroxylase, oxygenase from Rhodococcus sp. RHA1.
rcsb
source organism Rhodococcus sp.
total genus 149
structure length 388
sequence length 388
chains with identical sequence B, C, D
ec nomenclature ec 1.14.14.12: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase.
pdb deposition date 2007-10-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
A PF08028 Acyl-CoA_dh_2 Acyl-CoA dehydrogenase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 2rfqA01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 2rfqA03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 2rfqA02
2PG0A 3MPJA 2ZAFA 3MKHA 2RDZA 3BNHA 2VIGA 5K3JA 4X28A 4ZXVA 2YYLA 1QDBA 3R7KA 3UBRA 3BNJA 2UXWA 2FONA 4L3XA 2EBAA 1FS7A 2RF7A 2REHA 1IS2A 1EGDA 1W07A 3X0YA 3LGQA 3UU9A 3SWOA 4DOYA 2C12A 4Q17A 3HWCA 3SCEA 3S7WA 4P13A 3B96A 3FCJA 3BNGA 4OO2A 2VR0A 2D29A 3FO3A 4O5MA 3F29A 4Q4UA 3OWAA 4JEKA 3II9A 3GM6A 3L1TA 4WJYA 4IV6A 1SIQA 4RM7A 4ZYJA 4KCFA 1BUCA 4X28C 3TORA 3GQTA 1R2JA 2YYJA 3SF6A 3EOMA 1FS9A 1UDYA 4L3ZA 4G5EA 3MDDA 3NF4A 3OIBA 4KTOA 1GU6A 4Q5BA 2IX6A 1EGCA 2C0UA 2JBSA 2OR0A 2DDHA 2A1TA 2CX9A 4Q0TA 3D9EA 3SXQA 3RKHA 4M9AA 3MXLA 3TTBA 1EGEA 4HR3A 4N5FA 2YYGA 3D9DA 2E80A 1T9GA 4W9UA 2JIFA 1FS8A 5K3IA 4IRNA 3D9GA 2R0NA 3MMOA 5K3HA 3D1IA 4U83A 4NXLA 2YYIA 3MDEA 1JQIA 3GNCA 2JBTA 3AFEA 2ZO5A 3AFFA 3EONA 2YYKA 1WS9A 2R0MA 4L3YA 3X0XA 4Q1OA 2J7AA 1IVHA 3MPIA 2DVLA 2IX5A 3M9VA 1SIRA 3P4TA 4XVXA 5K3GA 4L1FA 4L38A 1OAHA 2OT4A 4Q5CA 2E81A 2Z1QA 3D6BA 1UKWA 1U8VA 2RFQA 3OWMA 3LG1A 2JBRA 2WBIA 2YYMA 3BNFA 3PFDA 3D9FA 1RX0A
chains in the Genus database with same CATH superfamily
3Q0AA 2PG0A 3MPJA 4F0XA 2AZEA 3C2PA 2ZAFA 4AKHA 1RP3A 5M4NA 4J1VA 4FF2A 2E0AA 3MKHA 2RDZA 4MP2A 2CJ7A 3BNHA 2VIGA 4E02A 5K3JA 1K90A 1RJ4A 2ZDYA 4X28A 2FP2A 4ZXVA 2F6LA 1QDBA 2YYLA 5J6AA 3VADA 3R7KA 1Y0VA 3UBRA 5M4MA 2OEVA 3BNJA 4AI6A 2UXWA 2FONA 3X29A 1K93A 4L3XA 3TZ2A 4JIZA 2EBAA 1FS7A 1Y8OA 2CJ4A 2REHA 2RF7A 1IS2A 1EGDA 1XG2B 2HJNA 1W07A 4HKRA 3X0YA 3VKHA 3LGQA 3CRLA 3UU9A 3SWOA 4DOYA 4MPNA 2OJQA 2C12A 2VF1A 2EBHX 3HWCA 4Q17A 3S7WA 3SCEA 4KSAA 4P13A 2YGWA 3B96A 3FCJA 2XS8A 3BNGA 2EBFX 3DJLA 4OO2A 2VR0A 3Q24A 3N0RA 4MPCA 2D29A 3FO3A 4O5MA 3F29A 3KMLA 2ZDXA 4Q4UA 3OWAA 4JEKA 4FF4A 3II9A 3GM6A 3L1TA 4WJYA 2XQRB 4IV6A 2XS1A 4H85A 1SIQA 2R02A 2AO2A 1XFZA 5B5WA 4RM7A 4ZYJA 2Q8IA 4KCFA 1BUCA 4X28C 2OEXA 3TORA 3GQTA 1R2JA 2YYJA 3SF6A 2QR4A 3EOMA 1FS9A 3BNFA 2CJ5A 1R3BA 1UDYA 1X8ZA 2BU6A 1Y8PA 4L3ZA 4G5EA 3MDDA 3NF4A 3OIBA 1LVCA 4QICA 3C3LA 4FF3A 4FZ4A 4KTOA 2BU2A 1GU6A 4E00A 3U33A 4Q5BA 2IX6A 2Q8GA 1EGCA 2C0UA 1K8TA 2JBSA 2OR0A 1PI1A 5B5VA 2DDHA 3TZ4A 2A1TA 2CX9A 4Q0TA 3D9EA 5M4PA 3SXQA 1GJVA 3RKHA 3Q23A 4M9AA 3MXLA 3TTBA 1JM6A 4H81A 1EGEA 4V26A 4HR3A 3TZ0A 4N5FA 1X91A 2YYGA 2PNRA 3D9DA 2E80A 1Y8NA 4HKSA 1T9GA 3D2RA 2Q8FA 4W9UA 4FF1A 4G97A 4AKGA 2JIFA 1PK0A 1FS8A 4MP7A 5K3IA 2BU8A 2CJ6A 4IRNA 1GKXA 5GJVE 3D9GA 2BU7A 1XFYA 2R05A 2PO4A 2R0NA 3MMOA 3VKGA 5K3HA 3D1IA 4LQQB 4U83A 2BTZA 2CJ8A 4LQSB 4NXLA 2YYIA 4JIOA 3MDEA 1JQIA 2FP1A 2LFWA 3GNCA 2JBTA 3AFEA 5GJWE 4MPEA 1SC5A 2ZO5A 4H7QA 3AFFA 3EONA 5BRMA 2Q8HA 2YYKA 1WS9A 1RJ1A 1XFVA 1XFUA 3C46A 2R0MA 4L3YA 3X0XA 4Q1OA 2J7AA 3Q22A 1IVHA 5EZ3A 3MPIA 2DVLA 2IX5A 3CRKA 1XFWA 3TZ5A 4E01A 3M9VA 4P79A 5J71A 2GBBA 1SIRA 3CE2A 5BRKA 3P4TA 1GKZA 4XVXA 4KS9A 4DZYA 5K3GA 4L1FA 4KSFA 4L38A 1OAHA 1SK6A 1XFXA 2R03A 2OT4A 1S26A 4Q5CA 5M4KA 2E81A 2Z1QA 5B6BA 3D6BA 1UKWA 1U8VA 1X90A 2EC5A 2RFQA 2ZKJA 3OWMA 4AKIA 3LG1A 2JBRA 2WBIA 4V25A 2YYMA 2BU5A 3PFDA 3D9FA 1RX0A
chains in the Genus database with same CATH topology
2PG0A 3MPJA 2ZAFA 3MKHA 2RDZA 3BNHA 2VIGA 5K3JA 4X28A 4ZXVA 2YYLA 1QDBA 3R7KA 3UBRA 3BNJA 2UXWA 2FONA 4L3XA 2EBAA 1FS7A 2RF7A 2REHA 1IS2A 1EGDA 1W07A 3X0YA 3LGQA 3UU9A 3SWOA 4DOYA 2C12A 4Q17A 3HWCA 3SCEA 3S7WA 4P13A 3B96A 3FCJA 3BNGA 4OO2A 2VR0A 2D29A 3FO3A 4O5MA 3F29A 4Q4UA 3OWAA 4JEKA 3II9A 3GM6A 3L1TA 4WJYA 4IV6A 1SIQA 4RM7A 4ZYJA 4KCFA 1BUCA 4X28C 3TORA 3GQTA 1R2JA 2YYJA 3SF6A 3EOMA 1FS9A 1UDYA 4L3ZA 4G5EA 3MDDA 3NF4A 3OIBA 4KTOA 1GU6A 4Q5BA 2IX6A 1EGCA 2C0UA 2JBSA 2OR0A 2DDHA 2A1TA 2CX9A 4Q0TA 3D9EA 3SXQA 3RKHA 4M9AA 3MXLA 3TTBA 1EGEA 4HR3A 4N5FA 2YYGA 3D9DA 2E80A 1T9GA 4W9UA 2JIFA 1FS8A 5K3IA 4IRNA 3D9GA 2R0NA 3MMOA 5K3HA 3D1IA 4U83A 4NXLA 2YYIA 3MDEA 1JQIA 3GNCA 2JBTA 3AFEA 2ZO5A 3AFFA 3EONA 2YYKA 1WS9A 2R0MA 4L3YA 3X0XA 4Q1OA 2J7AA 1IVHA 3MPIA 2DVLA 2IX5A 3M9VA 1SIRA 3P4TA 4XVXA 5K3GA 4L1FA 4L38A 1OAHA 2OT4A 4Q5CA 2E81A 2Z1QA 3D6BA 1UKWA 1U8VA 2RFQA 3OWMA 3LG1A 2JBRA 2WBIA 2YYMA 3BNFA 3PFDA 3D9FA 1RX0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PG0 A;  3MPJ A;  2ZAF A;  3MKH A;  2RDZ A;  3BNH A;  2VIG A;  5K3J A;  4X28 A;  4ZXV A;  2YYL A;  1QDB A;  3R7K A;  3UBR A;  3BNJ A;  2UXW A;  2FON A;  4L3X A;  2EBA A;  1FS7 A;  2RF7 A;  2REH A;  1IS2 A;  1EGD A;  1W07 A;  3X0Y A;  3LGQ A;  3UU9 A;  3SWO A;  4DOY A;  2C12 A;  4Q17 A;  3HWC A;  3SCE A;  3S7W A;  4P13 A;  3B96 A;  3FCJ A;  3BNG A;  4OO2 A;  2VR0 A;  2D29 A;  3FO3 A;  4O5M A;  3F29 A;  4Q4U A;  3OWA A;  4JEK A;  3II9 A;  3GM6 A;  3L1T A;  4WJY A;  4IV6 A;  1SIQ A;  4RM7 A;  4ZYJ A;  4KCF A;  1BUC A;  4X28 C;  3TOR A;  3GQT A;  1R2J A;  2YYJ A;  3SF6 A;  3EOM A;  1FS9 A;  1UDY A;  4L3Z A;  4G5E A;  3MDD A;  3NF4 A;  3OIB A;  4KTO A;  1GU6 A;  4Q5B A;  2IX6 A;  1EGC A;  2C0U A;  2JBS A;  2OR0 A;  2DDH A;  2A1T A;  2CX9 A;  4Q0T A;  3D9E A;  3SXQ A;  3RKH A;  4M9A A;  3MXL A;  3TTB A;  1EGE A;  4HR3 A;  4N5F A;  2YYG A;  3D9D A;  2E80 A;  1T9G A;  4W9U A;  2JIF A;  1FS8 A;  5K3I A;  4IRN A;  3D9G A;  2R0N A;  3MMO A;  5K3H A;  3D1I A;  4U83 A;  4NXL A;  2YYI A;  3MDE A;  1JQI A;  3GNC A;  2JBT A;  3AFE A;  2ZO5 A;  3AFF A;  3EON A;  2YYK A;  1WS9 A;  2R0M A;  4L3Y A;  3X0X A;  4Q1O A;  2J7A A;  1IVH A;  3MPI A;  2DVL A;  2IX5 A;  3M9V A;  1SIR A;  3P4T A;  4XVX A;  5K3G A;  4L1F A;  4L38 A;  1OAH A;  2OT4 A;  4Q5C A;  2E81 A;  2Z1Q A;  3D6B A;  1UKW A;  1U8V A;  2RFQ A;  3OWM A;  3LG1 A;  2JBR A;  2WBI A;  2YYM A;  3BNF A;  3PFD A;  3D9F A;  1RX0 A; 
#chains in the Genus database with same CATH topology
 3Q0A A;  2PG0 A;  3MPJ A;  4F0X A;  2AZE A;  3C2P A;  2ZAF A;  4AKH A;  1RP3 A;  5M4N A;  4J1V A;  4FF2 A;  2E0A A;  3MKH A;  2RDZ A;  4MP2 A;  2CJ7 A;  3BNH A;  2VIG A;  4E02 A;  5K3J A;  1K90 A;  1RJ4 A;  2ZDY A;  4X28 A;  2FP2 A;  4ZXV A;  2F6L A;  1QDB A;  2YYL A;  5J6A A;  3VAD A;  3R7K A;  1Y0V A;  3UBR A;  5M4M A;  2OEV A;  3BNJ A;  4AI6 A;  2UXW A;  2FON A;  3X29 A;  1K93 A;  4L3X A;  3TZ2 A;  4JIZ A;  2EBA A;  1FS7 A;  1Y8O A;  2CJ4 A;  2REH A;  2RF7 A;  1IS2 A;  1EGD A;  1XG2 B;  2HJN A;  1W07 A;  4HKR A;  3X0Y A;  3VKH A;  3LGQ A;  3CRL A;  3UU9 A;  3SWO A;  4DOY A;  4MPN A;  2OJQ A;  2C12 A;  2VF1 A;  2EBH X;  3HWC A;  4Q17 A;  3S7W A;  3SCE A;  4KSA A;  4P13 A;  2YGW A;  3B96 A;  3FCJ A;  2XS8 A;  3BNG A;  2EBF X;  3DJL A;  4OO2 A;  2VR0 A;  3Q24 A;  3N0R A;  4MPC A;  2D29 A;  3FO3 A;  4O5M A;  3F29 A;  3KML A;  2ZDX A;  4Q4U A;  3OWA A;  4JEK A;  4FF4 A;  3II9 A;  3GM6 A;  3L1T A;  4WJY A;  2XQR B;  4IV6 A;  2XS1 A;  4H85 A;  1SIQ A;  2R02 A;  2AO2 A;  1XFZ A;  5B5W A;  4RM7 A;  4ZYJ A;  2Q8I A;  4KCF A;  1BUC A;  4X28 C;  2OEX A;  3TOR A;  3GQT A;  1R2J A;  2YYJ A;  3SF6 A;  2QR4 A;  3EOM A;  1FS9 A;  3BNF A;  2CJ5 A;  1R3B A;  1UDY A;  1X8Z A;  2BU6 A;  1Y8P A;  4L3Z A;  4G5E A;  3MDD A;  3NF4 A;  3OIB A;  1LVC A;  4QIC A;  3C3L A;  4FF3 A;  4FZ4 A;  4KTO A;  2BU2 A;  1GU6 A;  4E00 A;  3U33 A;  4Q5B A;  2IX6 A;  2Q8G A;  1EGC A;  2C0U A;  1K8T A;  2JBS A;  2OR0 A;  1PI1 A;  5B5V A;  2DDH A;  3TZ4 A;  2A1T A;  2CX9 A;  4Q0T A;  3D9E A;  5M4P A;  3SXQ A;  1GJV A;  3RKH A;  3Q23 A;  4M9A A;  3MXL A;  3TTB A;  1JM6 A;  4H81 A;  1EGE A;  4V26 A;  4HR3 A;  3TZ0 A;  4N5F A;  1X91 A;  2YYG A;  2PNR A;  3D9D A;  2E80 A;  1Y8N A;  4HKS A;  1T9G A;  3D2R A;  2Q8F A;  4W9U A;  4FF1 A;  4G97 A;  4AKG A;  2JIF A;  1PK0 A;  1FS8 A;  4MP7 A;  5K3I A;  2BU8 A;  2CJ6 A;  4IRN A;  1GKX A;  5GJV E;  3D9G A;  2BU7 A;  1XFY A;  2R05 A;  2PO4 A;  2R0N A;  3MMO A;  3VKG A;  5K3H A;  3D1I A;  4LQQ B;  4U83 A;  2BTZ A;  2CJ8 A;  4LQS B;  4NXL A;  2YYI A;  4JIO A;  3MDE A;  1JQI A;  2FP1 A;  2LFW A;  3GNC A;  2JBT A;  3AFE A;  5GJW E;  4MPE A;  1SC5 A;  2ZO5 A;  4H7Q A;  3AFF A;  3EON A;  5BRM A;  2Q8H A;  2YYK A;  1WS9 A;  1RJ1 A;  1XFV A;  1XFU A;  3C46 A;  2R0M A;  4L3Y A;  3X0X A;  4Q1O A;  2J7A A;  3Q22 A;  1IVH A;  5EZ3 A;  3MPI A;  2DVL A;  2IX5 A;  3CRK A;  1XFW A;  3TZ5 A;  4E01 A;  3M9V A;  4P79 A;  5J71 A;  2GBB A;  1SIR A;  3CE2 A;  5BRK A;  3P4T A;  1GKZ A;  4XVX A;  4KS9 A;  4DZY A;  5K3G A;  4L1F A;  4KSF A;  4L38 A;  1OAH A;  1SK6 A;  1XFX A;  2R03 A;  2OT4 A;  1S26 A;  4Q5C A;  5M4K A;  2E81 A;  2Z1Q A;  5B6B A;  3D6B A;  1UKW A;  1U8V A;  1X90 A;  2EC5 A;  2RFQ A;  2ZKJ A;  3OWM A;  4AKI A;  3LG1 A;  2JBR A;  2WBI A;  4V25 A;  2YYM A;  2BU5 A;  3PFD A;  3D9F A;  1RX0 A; 
#chains in the Genus database with same CATH homology
 2PG0 A;  3MPJ A;  2ZAF A;  3MKH A;  2RDZ A;  3BNH A;  2VIG A;  5K3J A;  4X28 A;  4ZXV A;  2YYL A;  1QDB A;  3R7K A;  3UBR A;  3BNJ A;  2UXW A;  2FON A;  4L3X A;  2EBA A;  1FS7 A;  2RF7 A;  2REH A;  1IS2 A;  1EGD A;  1W07 A;  3X0Y A;  3LGQ A;  3UU9 A;  3SWO A;  4DOY A;  2C12 A;  4Q17 A;  3HWC A;  3SCE A;  3S7W A;  4P13 A;  3B96 A;  3FCJ A;  3BNG A;  4OO2 A;  2VR0 A;  2D29 A;  3FO3 A;  4O5M A;  3F29 A;  4Q4U A;  3OWA A;  4JEK A;  3II9 A;  3GM6 A;  3L1T A;  4WJY A;  4IV6 A;  1SIQ A;  4RM7 A;  4ZYJ A;  4KCF A;  1BUC A;  4X28 C;  3TOR A;  3GQT A;  1R2J A;  2YYJ A;  3SF6 A;  3EOM A;  1FS9 A;  1UDY A;  4L3Z A;  4G5E A;  3MDD A;  3NF4 A;  3OIB A;  4KTO A;  1GU6 A;  4Q5B A;  2IX6 A;  1EGC A;  2C0U A;  2JBS A;  2OR0 A;  2DDH A;  2A1T A;  2CX9 A;  4Q0T A;  3D9E A;  3SXQ A;  3RKH A;  4M9A A;  3MXL A;  3TTB A;  1EGE A;  4HR3 A;  4N5F A;  2YYG A;  3D9D A;  2E80 A;  1T9G A;  4W9U A;  2JIF A;  1FS8 A;  5K3I A;  4IRN A;  3D9G A;  2R0N A;  3MMO A;  5K3H A;  3D1I A;  4U83 A;  4NXL A;  2YYI A;  3MDE A;  1JQI A;  3GNC A;  2JBT A;  3AFE A;  2ZO5 A;  3AFF A;  3EON A;  2YYK A;  1WS9 A;  2R0M A;  4L3Y A;  3X0X A;  4Q1O A;  2J7A A;  1IVH A;  3MPI A;  2DVL A;  2IX5 A;  3M9V A;  1SIR A;  3P4T A;  4XVX A;  5K3G A;  4L1F A;  4L38 A;  1OAH A;  2OT4 A;  4Q5C A;  2E81 A;  2Z1Q A;  3D6B A;  1UKW A;  1U8V A;  2RFQ A;  3OWM A;  3LG1 A;  2JBR A;  2WBI A;  2YYM A;  3BNF A;  3PFD A;  3D9F A;  1RX0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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