3GNCA

Crystal structure of glutaryl-coa dehydrogenase from burkholderia pseudomallei with fragment 6421
Total Genus 150
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
150
sequence length
391
structure length
380
Chain Sequence
AATFHWDDPLLLDQQLADDERMVRDAAHAYAQGKLAPRVTEAFRHETTDAAIFREMGEIGLLGPTIPEQYGGPGLDYVSYGLIAREVERVDSGYRSMMSVQSSLVMVPIFEFGSDAQKEKYLPKLATGEWIGCFGLTEPMVTRARKVPGGYSLSGSKMWITNSPIADVFVVWAKLDEDRDEIRGFILEKGCKGLSAPAIHGKVGLRASITGEIVLDEAFVPEENILPHVKGLRGPFTCLNSARYGIAWGALGAAESCWHIARQYVLDRKQFGRPLAANQLIQKKLADMQTEITLGLQGVLRLGRMKDEGTAAVEITSIMKRNSCGKALDIARLARDMLGGNGDEFGVARHLVNLEVVNTYEGTHDIHALILGRAQTGIQA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Glutaryl-CoA dehydrogenase
publication title Probing conformational states of glutaryl-CoA dehydrogenase by fragment screening.
pubmed doi rcsb
source organism Burkholderia pseudomallei
molecule tags Oxidoreductase
total genus 150
structure length 380
sequence length 391
chains with identical sequence B, C, D
ec nomenclature ec 1.3.99.7: Transferred entry: 1.3.8.6.
pdb deposition date 2009-03-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 3gncA01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 3gncA03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 3gncA02
2OT4A 4JEKA 4XVXA 2RDZA 3X0XA 2VR0A 3P4TA 3GNCA 4ZYJA 3UBRA 4WJYA 1UKWA 3GQTA 3MPJA 2YYIA 3AFFA 3EONA 4X28A 2OR0A 1R2JA 4Q5CA 3D9FA 3LGQA 2C12A 4KTOA 4N5FA 2D29A 2FONA 2DDHA 2CX9A 3TTBA 4G5EA 4L3YA 3SWOA 2E80A 1T9GA 2C0UA 1QDBA 3SF6A 1SIQA 2R0NA 3MDEA 2IX5A 3FO3A 2ZAFA 1WS9A 2RFQA 4L38A 3GM6A 3SXQA 3B96A 2ZO5A 2A1TA 3BNGA 4Q1OA 1BUCA 4KCFA 5K3IA 2Z1QA 4ZXVA 1OAHA 1U8VA 4DOYA 1FS8A 1FS7A 1GU6A 4RM7A 2JBTA 3EOMA 3D9EA 2DVLA 3MKHA 3F29A 4Q0TA 1JQIA 3OIBA 1UDYA 3R7KA 3UU9A 4IV6A 2JIFA 4W9UA 1W07A 3S7WA 2RF7A 2YYKA 3D9GA 3M9VA 4X28C 2EBAA 4Q4UA 2PG0A 4O5MA 3OWMA 2YYGA 1EGEA 3MMOA 3X0YA 4Q17A 4M9AA 3MPIA 2WBIA 4L3ZA 1IVHA 3D1IA 4Q5BA 3RKHA 2REHA 3MDDA 4L3XA 2VIGA 3HWCA 4HR3A 5K3JA 3FCJA 2JBSA 3AFEA 1FS9A 1IS2A 4L1FA 4NXLA 5K3HA 3BNJA 3OWAA 4U83A 3MXLA 3BNFA 2JBRA 5K3GA 3LG1A 3SCEA 2E81A 1SIRA 3TORA 2UXWA 3BNHA 3D9DA 4OO2A 1RX0A 2J7AA 2YYMA 3L1TA 1EGDA 2IX6A 4IRNA 3NF4A 4P13A 2R0MA 2YYLA 3D6BA 3II9A 2YYJA 3PFDA 1EGCA
chains in the Genus database with same CATH superfamily
2OT4A 4JEKA 4XVXA 2RDZA 4FZ4A 1SC5A 1PK0A 1PI1A 3X0XA 3Q23A 2VR0A 3P4TA 3GNCA 3C46A 1XFZA 4ZYJA 1XFUA 4FF1A 3CRKA 3UBRA 1R3BA 2EBHX 4WJYA 4DZYA 1UKWA 3CE2A 3GQTA 3MPJA 2YYIA 4MP2A 3AFFA 3EONA 4X28A 2CJ4A 2OR0A 1R2JA 4FF3A 1JM6A 1XFVA 3D9FA 3LGQA 4Q5CA 4MPCA 2C12A 4KTOA 4N5FA 2D29A 2E0AA 2FONA 2DDHA 2CX9A 4E01A 3TTBA 4E02A 4G5EA 4L3YA 3SWOA 4AI6A 2E80A 5EZ3A 1T9GA 4KS9A 2C0UA 4V25A 5J6AA 4H85A 1QDBA 3SF6A 2CJ8A 2ZDYA 1LVCA 1SIQA 2R0NA 3CRLA 2OJQA 5GJWE 1K93A 3X29A 3C2PA 3VKGA 3MDEA 2IX5A 3FO3A 2R05A 2VF1A 3VADA 2EBFX 4G97A 1X90A 2GBBA 4LQQB 2ZAFA 3D2RA 4JIOA 2ZKJA 1WS9A 2XS8A 2RFQA 4L38A 4MPEA 2OEVA 3GM6A 2Q8HA 3B96A 2ZO5A 3N0RA 3SXQA 2A1TA 1Y8PA 3BNGA 4Q1OA 3TZ4A 1BUCA 4KCFA 5K3IA 2OEXA 3C3LA 2Z1QA 3Q0AA 4ZXVA 4V26A 1OAHA 1U8VA 5B5VA 2FP2A 4KSAA 4DOYA 2BU2A 2HJNA 1FS8A 1FS7A 1GU6A 2BU7A 4AKGA 3DJLA 4RM7A 4LQSB 2JBTA 3EOMA 3D9EA 2DVLA 4AKHA 3MKHA 3F29A 4Q0TA 3KMLA 1JQIA 3OIBA 1Y8OA 1UDYA 3R7KA 1GKXA 1XFYA 4IV6A 3UU9A 2JIFA 1Y8NA 4W9UA 2CJ5A 5M4KA 4JIZA 1W07A 2XQRB 4HKRA 5B5WA 3S7WA 3Q24A 5J71A 2RF7A 1SK6A 2CJ6A 2YYKA 2FP1A 4E00A 5BRKA 3D9GA 3M9VA 4X28C 2EBAA 4Q4UA 4H7QA 1XG2B 1GJVA 2PG0A 4QICA 4AKIA 4O5MA 3OWMA 2YYGA 3U33A 1EGEA 1X8ZA 2BU6A 3MMOA 3X0YA 4Q17A 4FF4A 4M9AA 4KSFA 3MPIA 1RJ4A 5M4NA 2WBIA 1K90A 2BU5A 4FF2A 4L3ZA 1IVHA 3D1IA 4Q5BA 3RKHA 2REHA 3MDDA 2AO2A 1RP3A 1GKZA 2R02A 2VIGA 3HWCA 2PNRA 4HR3A 4L3XA 2Q8IA 5K3JA 5BRMA 3FCJA 1Y0VA 2JBSA 2YGWA 2AZEA 3Q22A 1XFWA 2EC5A 4HKSA 1K8TA 2BU8A 4MPNA 1XFXA 1S26A 3AFEA 3TZ5A 5B6BA 1FS9A 3VKHA 1IS2A 4J1VA 4L1FA 2QR4A 4NXLA 5K3HA 2F6LA 2ZDXA 4P79A 2Q8GA 3BNJA 3OWAA 4U83A 5M4MA 3MXLA 2R03A 3TZ2A 3BNFA 1RJ1A 2JBRA 5K3GA 3LG1A 3SCEA 2E81A 2Q8FA 1SIRA 3TORA 4H81A 2UXWA 3BNHA 3D9DA 4OO2A 1X91A 1RX0A 2J7AA 2YYMA 3L1TA 5M4PA 1EGDA 4MP7A 2IX6A 4IRNA 3NF4A 4P13A 2R0MA 5GJVE 4F0XA 2YYLA 2XS1A 3D6BA 2PO4A 3II9A 2LFWA 2YYJA 2BTZA 3PFDA 3TZ0A 2CJ7A 1EGCA
chains in the Genus database with same CATH topology
2OT4A 4JEKA 4XVXA 2RDZA 3X0XA 2VR0A 3P4TA 3GNCA 4ZYJA 3UBRA 4WJYA 1UKWA 3GQTA 3MPJA 2YYIA 3AFFA 3EONA 4X28A 2OR0A 1R2JA 4Q5CA 3D9FA 3LGQA 2C12A 4KTOA 4N5FA 2D29A 2FONA 2DDHA 2CX9A 3TTBA 4G5EA 4L3YA 3SWOA 2E80A 1T9GA 2C0UA 1QDBA 3SF6A 1SIQA 2R0NA 3MDEA 2IX5A 3FO3A 2ZAFA 1WS9A 2RFQA 4L38A 3GM6A 3SXQA 3B96A 2ZO5A 2A1TA 3BNGA 4Q1OA 1BUCA 4KCFA 5K3IA 2Z1QA 4ZXVA 1OAHA 1U8VA 4DOYA 1FS8A 1FS7A 1GU6A 4RM7A 2JBTA 3EOMA 3D9EA 2DVLA 3MKHA 3F29A 4Q0TA 1JQIA 3OIBA 1UDYA 3R7KA 3UU9A 4IV6A 2JIFA 4W9UA 1W07A 3S7WA 2RF7A 2YYKA 3D9GA 3M9VA 4X28C 2EBAA 4Q4UA 2PG0A 4O5MA 3OWMA 2YYGA 1EGEA 3MMOA 3X0YA 4Q17A 4M9AA 3MPIA 2WBIA 4L3ZA 1IVHA 3D1IA 4Q5BA 3RKHA 2REHA 3MDDA 4L3XA 2VIGA 3HWCA 4HR3A 5K3JA 3FCJA 2JBSA 3AFEA 1FS9A 1IS2A 4L1FA 4NXLA 5K3HA 3BNJA 3OWAA 4U83A 3MXLA 3BNFA 2JBRA 5K3GA 3LG1A 3SCEA 2E81A 1SIRA 3TORA 2UXWA 3BNHA 3D9DA 4OO2A 1RX0A 2J7AA 2YYMA 3L1TA 1EGDA 2IX6A 4IRNA 3NF4A 4P13A 2R0MA 2YYLA 3D6BA 3II9A 2YYJA 3PFDA 1EGCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OT4 A;  4JEK A;  4XVX A;  2RDZ A;  3X0X A;  2VR0 A;  3P4T A;  3GNC A;  4ZYJ A;  3UBR A;  4WJY A;  1UKW A;  3GQT A;  3MPJ A;  2YYI A;  3AFF A;  3EON A;  4X28 A;  2OR0 A;  1R2J A;  4Q5C A;  3D9F A;  3LGQ A;  2C12 A;  4KTO A;  4N5F A;  2D29 A;  2FON A;  2DDH A;  2CX9 A;  3TTB A;  4G5E A;  4L3Y A;  3SWO A;  2E80 A;  1T9G A;  2C0U A;  1QDB A;  3SF6 A;  1SIQ A;  2R0N A;  3MDE A;  2IX5 A;  3FO3 A;  2ZAF A;  1WS9 A;  2RFQ A;  4L38 A;  3GM6 A;  3SXQ A;  3B96 A;  2ZO5 A;  2A1T A;  3BNG A;  4Q1O A;  1BUC A;  4KCF A;  5K3I A;  2Z1Q A;  4ZXV A;  1OAH A;  1U8V A;  4DOY A;  1FS8 A;  1FS7 A;  1GU6 A;  4RM7 A;  2JBT A;  3EOM A;  3D9E A;  2DVL A;  3MKH A;  3F29 A;  4Q0T A;  1JQI A;  3OIB A;  1UDY A;  3R7K A;  3UU9 A;  4IV6 A;  2JIF A;  4W9U A;  1W07 A;  3S7W A;  2RF7 A;  2YYK A;  3D9G A;  3M9V A;  4X28 C;  2EBA A;  4Q4U A;  2PG0 A;  4O5M A;  3OWM A;  2YYG A;  1EGE A;  3MMO A;  3X0Y A;  4Q17 A;  4M9A A;  3MPI A;  2WBI A;  4L3Z A;  1IVH A;  3D1I A;  4Q5B A;  3RKH A;  2REH A;  3MDD A;  4L3X A;  2VIG A;  3HWC A;  4HR3 A;  5K3J A;  3FCJ A;  2JBS A;  3AFE A;  1FS9 A;  1IS2 A;  4L1F A;  4NXL A;  5K3H A;  3BNJ A;  3OWA A;  4U83 A;  3MXL A;  3BNF A;  2JBR A;  5K3G A;  3LG1 A;  3SCE A;  2E81 A;  1SIR A;  3TOR A;  2UXW A;  3BNH A;  3D9D A;  4OO2 A;  1RX0 A;  2J7A A;  2YYM A;  3L1T A;  1EGD A;  2IX6 A;  4IRN A;  3NF4 A;  4P13 A;  2R0M A;  2YYL A;  3D6B A;  3II9 A;  2YYJ A;  3PFD A;  1EGC A; 
#chains in the Genus database with same CATH topology
 2OT4 A;  4JEK A;  4XVX A;  2RDZ A;  4FZ4 A;  1SC5 A;  1PK0 A;  1PI1 A;  3X0X A;  3Q23 A;  2VR0 A;  3P4T A;  3GNC A;  3C46 A;  1XFZ A;  4ZYJ A;  1XFU A;  4FF1 A;  3CRK A;  3UBR A;  1R3B A;  2EBH X;  4WJY A;  4DZY A;  1UKW A;  3CE2 A;  3GQT A;  3MPJ A;  2YYI A;  4MP2 A;  3AFF A;  3EON A;  4X28 A;  2CJ4 A;  2OR0 A;  1R2J A;  4FF3 A;  1JM6 A;  1XFV A;  3D9F A;  3LGQ A;  4Q5C A;  4MPC A;  2C12 A;  4KTO A;  4N5F A;  2D29 A;  2E0A A;  2FON A;  2DDH A;  2CX9 A;  4E01 A;  3TTB A;  4E02 A;  4G5E A;  4L3Y A;  3SWO A;  4AI6 A;  2E80 A;  5EZ3 A;  1T9G A;  4KS9 A;  2C0U A;  4V25 A;  5J6A A;  4H85 A;  1QDB A;  3SF6 A;  2CJ8 A;  2ZDY A;  1LVC A;  1SIQ A;  2R0N A;  3CRL A;  2OJQ A;  5GJW E;  1K93 A;  3X29 A;  3C2P A;  3VKG A;  3MDE A;  2IX5 A;  3FO3 A;  2R05 A;  2VF1 A;  3VAD A;  2EBF X;  4G97 A;  1X90 A;  2GBB A;  4LQQ B;  2ZAF A;  3D2R A;  4JIO A;  2ZKJ A;  1WS9 A;  2XS8 A;  2RFQ A;  4L38 A;  4MPE A;  2OEV A;  3GM6 A;  2Q8H A;  3B96 A;  2ZO5 A;  3N0R A;  3SXQ A;  2A1T A;  1Y8P A;  3BNG A;  4Q1O A;  3TZ4 A;  1BUC A;  4KCF A;  5K3I A;  2OEX A;  3C3L A;  2Z1Q A;  3Q0A A;  4ZXV A;  4V26 A;  1OAH A;  1U8V A;  5B5V A;  2FP2 A;  4KSA A;  4DOY A;  2BU2 A;  2HJN A;  1FS8 A;  1FS7 A;  1GU6 A;  2BU7 A;  4AKG A;  3DJL A;  4RM7 A;  4LQS B;  2JBT A;  3EOM A;  3D9E A;  2DVL A;  4AKH A;  3MKH A;  3F29 A;  4Q0T A;  3KML A;  1JQI A;  3OIB A;  1Y8O A;  1UDY A;  3R7K A;  1GKX A;  1XFY A;  4IV6 A;  3UU9 A;  2JIF A;  1Y8N A;  4W9U A;  2CJ5 A;  5M4K A;  4JIZ A;  1W07 A;  2XQR B;  4HKR A;  5B5W A;  3S7W A;  3Q24 A;  5J71 A;  2RF7 A;  1SK6 A;  2CJ6 A;  2YYK A;  2FP1 A;  4E00 A;  5BRK A;  3D9G A;  3M9V A;  4X28 C;  2EBA A;  4Q4U A;  4H7Q A;  1XG2 B;  1GJV A;  2PG0 A;  4QIC A;  4AKI A;  4O5M A;  3OWM A;  2YYG A;  3U33 A;  1EGE A;  1X8Z A;  2BU6 A;  3MMO A;  3X0Y A;  4Q17 A;  4FF4 A;  4M9A A;  4KSF A;  3MPI A;  1RJ4 A;  5M4N A;  2WBI A;  1K90 A;  2BU5 A;  4FF2 A;  4L3Z A;  1IVH A;  3D1I A;  4Q5B A;  3RKH A;  2REH A;  3MDD A;  2AO2 A;  1RP3 A;  1GKZ A;  2R02 A;  2VIG A;  3HWC A;  2PNR A;  4HR3 A;  4L3X A;  2Q8I A;  5K3J A;  5BRM A;  3FCJ A;  1Y0V A;  2JBS A;  2YGW A;  2AZE A;  3Q22 A;  1XFW A;  2EC5 A;  4HKS A;  1K8T A;  2BU8 A;  4MPN A;  1XFX A;  1S26 A;  3AFE A;  3TZ5 A;  5B6B A;  1FS9 A;  3VKH A;  1IS2 A;  4J1V A;  4L1F A;  2QR4 A;  4NXL A;  5K3H A;  2F6L A;  2ZDX A;  4P79 A;  2Q8G A;  3BNJ A;  3OWA A;  4U83 A;  5M4M A;  3MXL A;  2R03 A;  3TZ2 A;  3BNF A;  1RJ1 A;  2JBR A;  5K3G A;  3LG1 A;  3SCE A;  2E81 A;  2Q8F A;  1SIR A;  3TOR A;  4H81 A;  2UXW A;  3BNH A;  3D9D A;  4OO2 A;  1X91 A;  1RX0 A;  2J7A A;  2YYM A;  3L1T A;  5M4P A;  1EGD A;  4MP7 A;  2IX6 A;  4IRN A;  3NF4 A;  4P13 A;  2R0M A;  5GJV E;  4F0X A;  2YYL A;  2XS1 A;  3D6B A;  2PO4 A;  3II9 A;  2LFW A;  2YYJ A;  2BTZ A;  3PFD A;  3TZ0 A;  2CJ7 A;  1EGC A; 
#chains in the Genus database with same CATH homology
 2OT4 A;  4JEK A;  4XVX A;  2RDZ A;  3X0X A;  2VR0 A;  3P4T A;  3GNC A;  4ZYJ A;  3UBR A;  4WJY A;  1UKW A;  3GQT A;  3MPJ A;  2YYI A;  3AFF A;  3EON A;  4X28 A;  2OR0 A;  1R2J A;  4Q5C A;  3D9F A;  3LGQ A;  2C12 A;  4KTO A;  4N5F A;  2D29 A;  2FON A;  2DDH A;  2CX9 A;  3TTB A;  4G5E A;  4L3Y A;  3SWO A;  2E80 A;  1T9G A;  2C0U A;  1QDB A;  3SF6 A;  1SIQ A;  2R0N A;  3MDE A;  2IX5 A;  3FO3 A;  2ZAF A;  1WS9 A;  2RFQ A;  4L38 A;  3GM6 A;  3SXQ A;  3B96 A;  2ZO5 A;  2A1T A;  3BNG A;  4Q1O A;  1BUC A;  4KCF A;  5K3I A;  2Z1Q A;  4ZXV A;  1OAH A;  1U8V A;  4DOY A;  1FS8 A;  1FS7 A;  1GU6 A;  4RM7 A;  2JBT A;  3EOM A;  3D9E A;  2DVL A;  3MKH A;  3F29 A;  4Q0T A;  1JQI A;  3OIB A;  1UDY A;  3R7K A;  3UU9 A;  4IV6 A;  2JIF A;  4W9U A;  1W07 A;  3S7W A;  2RF7 A;  2YYK A;  3D9G A;  3M9V A;  4X28 C;  2EBA A;  4Q4U A;  2PG0 A;  4O5M A;  3OWM A;  2YYG A;  1EGE A;  3MMO A;  3X0Y A;  4Q17 A;  4M9A A;  3MPI A;  2WBI A;  4L3Z A;  1IVH A;  3D1I A;  4Q5B A;  3RKH A;  2REH A;  3MDD A;  4L3X A;  2VIG A;  3HWC A;  4HR3 A;  5K3J A;  3FCJ A;  2JBS A;  3AFE A;  1FS9 A;  1IS2 A;  4L1F A;  4NXL A;  5K3H A;  3BNJ A;  3OWA A;  4U83 A;  3MXL A;  3BNF A;  2JBR A;  5K3G A;  3LG1 A;  3SCE A;  2E81 A;  1SIR A;  3TOR A;  2UXW A;  3BNH A;  3D9D A;  4OO2 A;  1RX0 A;  2J7A A;  2YYM A;  3L1T A;  1EGD A;  2IX6 A;  4IRN A;  3NF4 A;  4P13 A;  2R0M A;  2YYL A;  3D6B A;  3II9 A;  2YYJ A;  3PFD A;  1EGC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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