3AFEA

Crystal structure of the hsaa monooxygenase from m.tuberculosis
Total Genus 144
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
144
sequence length
388
structure length
384
Chain Sequence
RDAQSVLAAIDNLLPEIRDRAQATEDLRRLPDETVKALDDVGFFTLLQPQQWGGLQCDPALFFEATRRLASVCGSTGWVSSIVGVHNWHLALFDQRAQEEVWGEDPSTRISSSYAPMGAGVVVDGGYLVNGSWNWSSGCDHASWTFVGGPVIKDGRPVDFGSFLIPRSEYEIKDVWYVVGLRGTGSNTLVVKDVFVPRHRFLSYKAMNDHTAGGLATNSAPVYKMPWGTMHPTTISAPIVGMAYGAYAAHVEHQGKRVRAAFAGAKDDPFAKVRIAEAASDIDAAWRQLIGNVSDEYALLAAGKEIPFELRARARRDQVRATGRSIASIDRLFEASGATALSNEAPIQRFWRDAHAGRVHAANDPERAYVIFGNHEFGLPPTMV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Hydroxylase, putative
publication title A flavin-dependent monooxygenase from Mycobacterium tuberculosis involved in cholesterol catabolism
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Oxidoreductase
total genus 144
structure length 384
sequence length 388
chains with identical sequence B, C, D
ec nomenclature ec 1.14.14.12: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase.
pdb deposition date 2010-02-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08028 Acyl-CoA_dh_2 Acyl-CoA dehydrogenase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 3afeA01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 3afeA03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 3afeA02
3TTBA 4ZXVA 3MKHA 3MPIA 4IV6A 3II9A 3SXQA 3GQTA 2CX9A 4L1FA 3UBRA 2VIGA 2WBIA 3D9EA 3D9FA 5K3JA 3AFFA 2A1TA 3OWAA 4O5MA 1IVHA 2RF7A 2YYJA 4JEKA 3D6BA 4KCFA 4W9UA 3X0YA 3BNHA 1FS9A 4L3ZA 4N5FA 1RX0A 1FS7A 4Q4UA 2YYMA 1EGDA 3BNFA 4L3XA 4Q5BA 2E81A 2IX6A 2YYLA 3S7WA 1BUCA 2J7AA 3P4TA 3NF4A 4L38A 3SF6A 3AFEA 3MDDA 3PFDA 2OR0A 3D9DA 2C0UA 2YYIA 1SIRA 3OIBA 3MPJA 3BNGA 2Z1QA 3MMOA 4RM7A 2IX5A 4KTOA 1U8VA 1GU6A 2FONA 2JBRA 5K3HA 4Q5CA 3MDEA 2DDHA 4OO2A 4IRNA 3B96A 4XVXA 3HWCA 1W07A 2D29A 4Q17A 1OAHA 3FCJA 1QDBA 3OWMA 3UU9A 3D9GA 3LGQA 3TORA 1EGCA 2JIFA 1R2JA 2RDZA 4G5EA 2R0MA 2OT4A 3EOMA 5K3IA 1UKWA 4ZYJA 3LG1A 2E80A 2RFQA 1UDYA 4U83A 2VR0A 2REHA 3M9VA 1JQIA 3GNCA 3X0XA 4X28A 2YYKA 2R0NA 2YYGA 3RKHA 4P13A 1WS9A 3EONA 2JBTA 3F29A 3R7KA 3L1TA 4NXLA 1SIQA 4Q0TA 2ZAFA 1FS8A 2JBSA 5K3GA 3SCEA 3FO3A 3GM6A 4DOYA 2PG0A 3BNJA 4Q1OA 3D1IA 4L3YA 1T9GA 2ZO5A 3SWOA 2DVLA 2UXWA 4X28C 4WJYA 4HR3A 1IS2A 2EBAA 4M9AA 3MXLA 2C12A 1EGEA
chains in the Genus database with same CATH superfamily
1JM6A 1SK6A 3TTBA 4ZXVA 3MKHA 3MPIA 4IV6A 2XS1A 3II9A 5BRMA 3GQTA 3SXQA 2PO4A 3DJLA 1X8ZA 2CX9A 2FP1A 5M4KA 2R02A 4L1FA 3UBRA 2VIGA 1XFUA 2WBIA 3D9EA 3D9FA 5K3JA 3AFFA 4H85A 2A1TA 3OWAA 4O5MA 1GKXA 1GKZA 5B6BA 3VADA 1XFWA 1IVHA 5B5WA 2CJ7A 2RF7A 4E00A 4LQSB 1S26A 2YGWA 2YYJA 4JEKA 4V26A 4KSAA 2AO2A 3D6BA 4KCFA 4W9UA 3X0YA 2LFWA 1FS9A 3BNHA 4L3ZA 4N5FA 1RX0A 1FS7A 4Q4UA 2Q8HA 4FF4A 2YYMA 1EGDA 1Y8OA 3BNFA 4L3XA 2E81A 4Q5BA 3TZ0A 4FF3A 1X91A 2IX6A 1Y0VA 2XQRB 2CJ5A 2YYLA 3CRLA 3S7WA 1BUCA 4QICA 2J7AA 3C2PA 1K90A 3P4TA 3NF4A 3Q24A 4L38A 5GJWE 3SF6A 3AFEA 2BU6A 3MDDA 3PFDA 4JIOA 4AI6A 2OR0A 3D9DA 2C0UA 1XFXA 4JIZA 2YYIA 4DZYA 5M4PA 2HJNA 1SIRA 3OIBA 3MPJA 2VF1A 2Z1QA 3BNGA 2OEXA 4V25A 4MPCA 5GJVE 2R03A 3MMOA 4AKIA 2ZDYA 3U33A 4RM7A 2IX5A 4E02A 4KTOA 1U8VA 4AKHA 1X90A 3VKHA 1R3BA 2Q8IA 1XFZA 1GU6A 1Y8PA 2FONA 4FF2A 2JBRA 5K3HA 4Q5CA 3MDEA 2DDHA 4OO2A 4IRNA 2EBHX 3B96A 4XVXA 4MPNA 2ZDXA 1W07A 3HWCA 2BU8A 2D29A 3X29A 4Q17A 1OAHA 3FCJA 1QDBA 1XFVA 3OWMA 4MPEA 1GJVA 3UU9A 3D9GA 3LGQA 2R05A 3TORA 1EGCA 5BRKA 3TZ2A 2JIFA 1R2JA 2RDZA 1Y8NA 4G5EA 5M4MA 2R0MA 1RP3A 2OT4A 2Q8GA 1LVCA 3EOMA 5K3IA 1UKWA 4ZYJA 2XS8A 3LG1A 2E80A 5B5VA 3N0RA 4KSFA 1PI1A 2RFQA 1UDYA 2E0AA 4U83A 2VR0A 3VKGA 2REHA 3M9VA 2BU7A 2QR4A 3Q0AA 1JQIA 3GNCA 3X0XA 4X28A 3D2RA 2EBFX 2YYKA 2R0NA 2YYGA 3CE2A 3RKHA 4P79A 4P13A 1WS9A 3EONA 2JBTA 4MP7A 3Q22A 3F29A 3R7KA 2AZEA 4NXLA 3CRKA 1SIQA 3L1TA 2ZAFA 1FS8A 2JBSA 2BTZA 5K3GA 4Q0TA 3TZ4A 4F0XA 3Q23A 3SCEA 1RJ1A 4HKRA 3FO3A 5EZ3A 2BU5A 1XG2B 2ZKJA 4AKGA 2OJQA 4H81A 2OEVA 4HKSA 2F6LA 3TZ5A 3C46A 3GM6A 2CJ8A 4DOYA 1K8TA 4J1VA 5J71A 1SC5A 2PG0A 1RJ4A 2CJ4A 3KMLA 3BNJA 4MP2A 5J6AA 1PK0A 4Q1OA 1K93A 4LQQB 3D1IA 4H7QA 2PNRA 2CJ6A 4L3YA 4KS9A 1T9GA 2ZO5A 4E01A 3SWOA 2DVLA 4G97A 2UXWA 5M4NA 2EC5A 4X28C 4WJYA 2Q8FA 4HR3A 4FF1A 1IS2A 2EBAA 4M9AA 2GBBA 4FZ4A 1XFYA 2FP2A 3C3LA 3MXLA 2C12A 1EGEA 2BU2A
chains in the Genus database with same CATH topology
3TTBA 4ZXVA 3MKHA 3MPIA 4IV6A 3II9A 3SXQA 3GQTA 2CX9A 4L1FA 3UBRA 2VIGA 2WBIA 3D9EA 3D9FA 5K3JA 3AFFA 2A1TA 3OWAA 4O5MA 1IVHA 2RF7A 2YYJA 4JEKA 3D6BA 4KCFA 4W9UA 3X0YA 3BNHA 1FS9A 4L3ZA 4N5FA 1RX0A 1FS7A 4Q4UA 2YYMA 1EGDA 3BNFA 4L3XA 4Q5BA 2E81A 2IX6A 2YYLA 3S7WA 1BUCA 2J7AA 3P4TA 3NF4A 4L38A 3SF6A 3AFEA 3MDDA 3PFDA 2OR0A 3D9DA 2C0UA 2YYIA 1SIRA 3OIBA 3MPJA 3BNGA 2Z1QA 3MMOA 4RM7A 2IX5A 4KTOA 1U8VA 1GU6A 2FONA 2JBRA 5K3HA 4Q5CA 3MDEA 2DDHA 4OO2A 4IRNA 3B96A 4XVXA 3HWCA 1W07A 2D29A 4Q17A 1OAHA 3FCJA 1QDBA 3OWMA 3UU9A 3D9GA 3LGQA 3TORA 1EGCA 2JIFA 1R2JA 2RDZA 4G5EA 2R0MA 2OT4A 3EOMA 5K3IA 1UKWA 4ZYJA 3LG1A 2E80A 2RFQA 1UDYA 4U83A 2VR0A 2REHA 3M9VA 1JQIA 3GNCA 3X0XA 4X28A 2YYKA 2R0NA 2YYGA 3RKHA 4P13A 1WS9A 3EONA 2JBTA 3F29A 3R7KA 3L1TA 4NXLA 1SIQA 4Q0TA 2ZAFA 1FS8A 2JBSA 5K3GA 3SCEA 3FO3A 3GM6A 4DOYA 2PG0A 3BNJA 4Q1OA 3D1IA 4L3YA 1T9GA 2ZO5A 3SWOA 2DVLA 2UXWA 4X28C 4WJYA 4HR3A 1IS2A 2EBAA 4M9AA 3MXLA 2C12A 1EGEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TTB A;  4ZXV A;  3MKH A;  3MPI A;  4IV6 A;  3II9 A;  3SXQ A;  3GQT A;  2CX9 A;  4L1F A;  3UBR A;  2VIG A;  2WBI A;  3D9E A;  3D9F A;  5K3J A;  3AFF A;  2A1T A;  3OWA A;  4O5M A;  1IVH A;  2RF7 A;  2YYJ A;  4JEK A;  3D6B A;  4KCF A;  4W9U A;  3X0Y A;  3BNH A;  1FS9 A;  4L3Z A;  4N5F A;  1RX0 A;  1FS7 A;  4Q4U A;  2YYM A;  1EGD A;  3BNF A;  4L3X A;  4Q5B A;  2E81 A;  2IX6 A;  2YYL A;  3S7W A;  1BUC A;  2J7A A;  3P4T A;  3NF4 A;  4L38 A;  3SF6 A;  3AFE A;  3MDD A;  3PFD A;  2OR0 A;  3D9D A;  2C0U A;  2YYI A;  1SIR A;  3OIB A;  3MPJ A;  3BNG A;  2Z1Q A;  3MMO A;  4RM7 A;  2IX5 A;  4KTO A;  1U8V A;  1GU6 A;  2FON A;  2JBR A;  5K3H A;  4Q5C A;  3MDE A;  2DDH A;  4OO2 A;  4IRN A;  3B96 A;  4XVX A;  3HWC A;  1W07 A;  2D29 A;  4Q17 A;  1OAH A;  3FCJ A;  1QDB A;  3OWM A;  3UU9 A;  3D9G A;  3LGQ A;  3TOR A;  1EGC A;  2JIF A;  1R2J A;  2RDZ A;  4G5E A;  2R0M A;  2OT4 A;  3EOM A;  5K3I A;  1UKW A;  4ZYJ A;  3LG1 A;  2E80 A;  2RFQ A;  1UDY A;  4U83 A;  2VR0 A;  2REH A;  3M9V A;  1JQI A;  3GNC A;  3X0X A;  4X28 A;  2YYK A;  2R0N A;  2YYG A;  3RKH A;  4P13 A;  1WS9 A;  3EON A;  2JBT A;  3F29 A;  3R7K A;  3L1T A;  4NXL A;  1SIQ A;  4Q0T A;  2ZAF A;  1FS8 A;  2JBS A;  5K3G A;  3SCE A;  3FO3 A;  3GM6 A;  4DOY A;  2PG0 A;  3BNJ A;  4Q1O A;  3D1I A;  4L3Y A;  1T9G A;  2ZO5 A;  3SWO A;  2DVL A;  2UXW A;  4X28 C;  4WJY A;  4HR3 A;  1IS2 A;  2EBA A;  4M9A A;  3MXL A;  2C12 A;  1EGE A; 
#chains in the Genus database with same CATH topology
 1JM6 A;  1SK6 A;  3TTB A;  4ZXV A;  3MKH A;  3MPI A;  4IV6 A;  2XS1 A;  3II9 A;  5BRM A;  3GQT A;  3SXQ A;  2PO4 A;  3DJL A;  1X8Z A;  2CX9 A;  2FP1 A;  5M4K A;  2R02 A;  4L1F A;  3UBR A;  2VIG A;  1XFU A;  2WBI A;  3D9E A;  3D9F A;  5K3J A;  3AFF A;  4H85 A;  2A1T A;  3OWA A;  4O5M A;  1GKX A;  1GKZ A;  5B6B A;  3VAD A;  1XFW A;  1IVH A;  5B5W A;  2CJ7 A;  2RF7 A;  4E00 A;  4LQS B;  1S26 A;  2YGW A;  2YYJ A;  4JEK A;  4V26 A;  4KSA A;  2AO2 A;  3D6B A;  4KCF A;  4W9U A;  3X0Y A;  2LFW A;  1FS9 A;  3BNH A;  4L3Z A;  4N5F A;  1RX0 A;  1FS7 A;  4Q4U A;  2Q8H A;  4FF4 A;  2YYM A;  1EGD A;  1Y8O A;  3BNF A;  4L3X A;  2E81 A;  4Q5B A;  3TZ0 A;  4FF3 A;  1X91 A;  2IX6 A;  1Y0V A;  2XQR B;  2CJ5 A;  2YYL A;  3CRL A;  3S7W A;  1BUC A;  4QIC A;  2J7A A;  3C2P A;  1K90 A;  3P4T A;  3NF4 A;  3Q24 A;  4L38 A;  5GJW E;  3SF6 A;  3AFE A;  2BU6 A;  3MDD A;  3PFD A;  4JIO A;  4AI6 A;  2OR0 A;  3D9D A;  2C0U A;  1XFX A;  4JIZ A;  2YYI A;  4DZY A;  5M4P A;  2HJN A;  1SIR A;  3OIB A;  3MPJ A;  2VF1 A;  2Z1Q A;  3BNG A;  2OEX A;  4V25 A;  4MPC A;  5GJV E;  2R03 A;  3MMO A;  4AKI A;  2ZDY A;  3U33 A;  4RM7 A;  2IX5 A;  4E02 A;  4KTO A;  1U8V A;  4AKH A;  1X90 A;  3VKH A;  1R3B A;  2Q8I A;  1XFZ A;  1GU6 A;  1Y8P A;  2FON A;  4FF2 A;  2JBR A;  5K3H A;  4Q5C A;  3MDE A;  2DDH A;  4OO2 A;  4IRN A;  2EBH X;  3B96 A;  4XVX A;  4MPN A;  2ZDX A;  1W07 A;  3HWC A;  2BU8 A;  2D29 A;  3X29 A;  4Q17 A;  1OAH A;  3FCJ A;  1QDB A;  1XFV A;  3OWM A;  4MPE A;  1GJV A;  3UU9 A;  3D9G A;  3LGQ A;  2R05 A;  3TOR A;  1EGC A;  5BRK A;  3TZ2 A;  2JIF A;  1R2J A;  2RDZ A;  1Y8N A;  4G5E A;  5M4M A;  2R0M A;  1RP3 A;  2OT4 A;  2Q8G A;  1LVC A;  3EOM A;  5K3I A;  1UKW A;  4ZYJ A;  2XS8 A;  3LG1 A;  2E80 A;  5B5V A;  3N0R A;  4KSF A;  1PI1 A;  2RFQ A;  1UDY A;  2E0A A;  4U83 A;  2VR0 A;  3VKG A;  2REH A;  3M9V A;  2BU7 A;  2QR4 A;  3Q0A A;  1JQI A;  3GNC A;  3X0X A;  4X28 A;  3D2R A;  2EBF X;  2YYK A;  2R0N A;  2YYG A;  3CE2 A;  3RKH A;  4P79 A;  4P13 A;  1WS9 A;  3EON A;  2JBT A;  4MP7 A;  3Q22 A;  3F29 A;  3R7K A;  2AZE A;  4NXL A;  3CRK A;  1SIQ A;  3L1T A;  2ZAF A;  1FS8 A;  2JBS A;  2BTZ A;  5K3G A;  4Q0T A;  3TZ4 A;  4F0X A;  3Q23 A;  3SCE A;  1RJ1 A;  4HKR A;  3FO3 A;  5EZ3 A;  2BU5 A;  1XG2 B;  2ZKJ A;  4AKG A;  2OJQ A;  4H81 A;  2OEV A;  4HKS A;  2F6L A;  3TZ5 A;  3C46 A;  3GM6 A;  2CJ8 A;  4DOY A;  1K8T A;  4J1V A;  5J71 A;  1SC5 A;  2PG0 A;  1RJ4 A;  2CJ4 A;  3KML A;  3BNJ A;  4MP2 A;  5J6A A;  1PK0 A;  4Q1O A;  1K93 A;  4LQQ B;  3D1I A;  4H7Q A;  2PNR A;  2CJ6 A;  4L3Y A;  4KS9 A;  1T9G A;  2ZO5 A;  4E01 A;  3SWO A;  2DVL A;  4G97 A;  2UXW A;  5M4N A;  2EC5 A;  4X28 C;  4WJY A;  2Q8F A;  4HR3 A;  4FF1 A;  1IS2 A;  2EBA A;  4M9A A;  2GBB A;  4FZ4 A;  1XFY A;  2FP2 A;  3C3L A;  3MXL A;  2C12 A;  1EGE A;  2BU2 A; 
#chains in the Genus database with same CATH homology
 3TTB A;  4ZXV A;  3MKH A;  3MPI A;  4IV6 A;  3II9 A;  3SXQ A;  3GQT A;  2CX9 A;  4L1F A;  3UBR A;  2VIG A;  2WBI A;  3D9E A;  3D9F A;  5K3J A;  3AFF A;  2A1T A;  3OWA A;  4O5M A;  1IVH A;  2RF7 A;  2YYJ A;  4JEK A;  3D6B A;  4KCF A;  4W9U A;  3X0Y A;  3BNH A;  1FS9 A;  4L3Z A;  4N5F A;  1RX0 A;  1FS7 A;  4Q4U A;  2YYM A;  1EGD A;  3BNF A;  4L3X A;  4Q5B A;  2E81 A;  2IX6 A;  2YYL A;  3S7W A;  1BUC A;  2J7A A;  3P4T A;  3NF4 A;  4L38 A;  3SF6 A;  3AFE A;  3MDD A;  3PFD A;  2OR0 A;  3D9D A;  2C0U A;  2YYI A;  1SIR A;  3OIB A;  3MPJ A;  3BNG A;  2Z1Q A;  3MMO A;  4RM7 A;  2IX5 A;  4KTO A;  1U8V A;  1GU6 A;  2FON A;  2JBR A;  5K3H A;  4Q5C A;  3MDE A;  2DDH A;  4OO2 A;  4IRN A;  3B96 A;  4XVX A;  3HWC A;  1W07 A;  2D29 A;  4Q17 A;  1OAH A;  3FCJ A;  1QDB A;  3OWM A;  3UU9 A;  3D9G A;  3LGQ A;  3TOR A;  1EGC A;  2JIF A;  1R2J A;  2RDZ A;  4G5E A;  2R0M A;  2OT4 A;  3EOM A;  5K3I A;  1UKW A;  4ZYJ A;  3LG1 A;  2E80 A;  2RFQ A;  1UDY A;  4U83 A;  2VR0 A;  2REH A;  3M9V A;  1JQI A;  3GNC A;  3X0X A;  4X28 A;  2YYK A;  2R0N A;  2YYG A;  3RKH A;  4P13 A;  1WS9 A;  3EON A;  2JBT A;  3F29 A;  3R7K A;  3L1T A;  4NXL A;  1SIQ A;  4Q0T A;  2ZAF A;  1FS8 A;  2JBS A;  5K3G A;  3SCE A;  3FO3 A;  3GM6 A;  4DOY A;  2PG0 A;  3BNJ A;  4Q1O A;  3D1I A;  4L3Y A;  1T9G A;  2ZO5 A;  3SWO A;  2DVL A;  2UXW A;  4X28 C;  4WJY A;  4HR3 A;  1IS2 A;  2EBA A;  4M9A A;  3MXL A;  2C12 A;  1EGE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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