2A1TA

Structure of the human mcad:etf e165betaa complex
Total Genus 145
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
145
sequence length
386
structure length
386
Chain Sequence
LGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDKYK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Acyl-CoA dehydrogenase, medium-chain specific, mitochondrial
publication title Stabilization of Non-productive Conformations Underpins Rapid Electron Transfer to Electron-transferring Flavoprotein
pubmed doi rcsb
source organism Homo sapiens
molecule tags Oxidoreductase/electron transport
total genus 145
structure length 386
sequence length 386
chains with identical sequence B, C, D
ec nomenclature ec 1.3.8.7: Medium-chain acyl-CoA dehydrogenase.
pdb deposition date 2005-06-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 2a1tA01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 2a1tA03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 2a1tA02
1BUCA 2EBAA 4DOYA 3FCJA 2RDZA 3HWCA 3SXQA 3AFFA 2IX6A 1GU6A 1EGDA 2YYIA 3EONA 2YYMA 1QDBA 3D9EA 1FS8A 5K3HA 3MPIA 2C12A 3BNHA 4L3ZA 1UKWA 3D9DA 4Q1OA 3EOMA 4W9UA 3R7KA 3P4TA 4L1FA 4N5FA 2JIFA 2A1TA 4ZXVA 2R0MA 3UU9A 4IRNA 3RKHA 3FO3A 3MXLA 3OIBA 2DVLA 1U8VA 2OR0A 2OT4A 3SCEA 3M9VA 4Q17A 2DDHA 1RX0A 4M9AA 4KCFA 4ZYJA 1W07A 4X28A 1UDYA 1IS2A 3MKHA 4IV6A 4KTOA 4O5MA 3AFEA 1SIQA 1EGEA 3X0XA 1IVHA 1FS9A 3SWOA 3SF6A 2E81A 2E80A 3OWAA 1EGCA 2VR0A 2D29A 4P13A 4NXLA 4RM7A 4Q5CA 4WJYA 2JBSA 5K3GA 2REHA 3TTBA 2WBIA 2YYLA 2JBTA 3BNFA 1FS7A 4G5EA 2ZO5A 3X0YA 4Q5BA 3PFDA 2RFQA 3S7WA 1WS9A 2R0NA 3MDDA 3GNCA 4L38A 2YYKA 2YYGA 4L3XA 2CX9A 2Z1QA 3MDEA 3D6BA 4Q0TA 4HR3A 3LGQA 4L3YA 3L1TA 2PG0A 3LG1A 3UBRA 1T9GA 2J7AA 3D9FA 3MPJA 5K3IA 2JBRA 1JQIA 4X28C 3BNJA 3II9A 4U83A 5K3JA 2FONA 1OAHA 1SIRA 4XVXA 3D1IA 3GQTA 4JEKA 2ZAFA 2UXWA 3BNGA 4Q4UA 3TORA 3NF4A 2RF7A 3F29A 2YYJA 3GM6A 3MMOA 4OO2A 1R2JA 2IX5A 3OWMA 3D9GA 3B96A 2C0UA 2VIGA
chains in the Genus database with same CATH superfamily
1Y0VA 3KMLA 1BUCA 2EBAA 4DOYA 1JM6A 2ZDXA 4AKIA 3U33A 3FCJA 1Y8NA 3X29A 2RDZA 4MPEA 3HWCA 2BTZA 2XQRB 3AFFA 2AO2A 3SXQA 2IX6A 1GU6A 1EGDA 2YYIA 3EONA 2YYMA 4LQSB 1QDBA 3D9EA 1RJ4A 1FS8A 5K3HA 4FF2A 3MPIA 2C12A 3BNHA 4L3ZA 2CJ8A 5B5VA 1UKWA 2BU8A 3D9DA 4Q1OA 3EOMA 4W9UA 4HKRA 1XFXA 2Q8HA 3VKGA 2LFWA 3R7KA 3P4TA 2PO4A 4L1FA 5J71A 5M4MA 4N5FA 1Y8OA 2JIFA 2A1TA 3TZ4A 2R05A 1PI1A 1K93A 1R3BA 2ZKJA 4H81A 2EBHX 5BRKA 4ZXVA 2R0MA 3UU9A 4IRNA 1X8ZA 1XFVA 3FO3A 1XFZA 4MPNA 3MXLA 4JIOA 3OIBA 4V25A 3RKHA 2DVLA 1U8VA 2OR0A 2E0AA 2OT4A 3SCEA 4E01A 3Q0AA 3M9VA 1XFWA 2DDHA 4Q17A 3Q24A 1RX0A 4M9AA 4KCFA 4ZYJA 1W07A 2BU6A 4E00A 1SC5A 4X28A 1UDYA 5B6BA 1IS2A 3MKHA 4IV6A 4KTOA 4O5MA 4FF1A 2CJ7A 2OEXA 3AFEA 2Q8GA 1SIQA 1EGEA 3Q22A 3X0XA 2CJ6A 5BRMA 3VKHA 1IVHA 1GKZA 2HJNA 5M4PA 2XS1A 2CJ5A 1FS9A 3SWOA 3SF6A 2VF1A 2E81A 4G97A 2E80A 4QICA 3OWAA 1EGCA 1K90A 5B5WA 2AZEA 2VR0A 2D29A 2R02A 4H85A 4P13A 4H7QA 4NXLA 1K8TA 4RM7A 2R03A 4Q5CA 2JBSA 5K3GA 4WJYA 3N0RA 2REHA 3TTBA 3CRKA 5J6AA 2WBIA 4FZ4A 2YYLA 2JBTA 3BNFA 1FS7A 4G5EA 4DZYA 2ZO5A 2Q8IA 3CRLA 3X0YA 4Q5BA 2Q8FA 3VADA 1XG2B 3PFDA 2RFQA 3S7WA 1WS9A 2R0NA 2BU7A 2GBBA 3MDDA 2BU5A 5GJVE 4V26A 3GNCA 2XS8A 2EC5A 4HKSA 2YYKA 3D2RA 4L38A 2YYGA 4L3XA 2CX9A 4E02A 5M4NA 3C46A 2Z1QA 3MDEA 3D6BA 3TZ0A 4Q0TA 4HR3A 4MPCA 3LGQA 4L3YA 4KS9A 3L1TA 2PG0A 3LG1A 3UBRA 1T9GA 1GJVA 1Y8PA 2PNRA 2FP1A 2J7AA 3CE2A 4LQQB 4F0XA 5EZ3A 3D9FA 3MPJA 1LVCA 2YGWA 5K3IA 4KSFA 2JBRA 5GJWE 4J1VA 3Q23A 1XFUA 3C2PA 4FF3A 1JQIA 4X28C 2ZDYA 3BNJA 4AKHA 2FP2A 3TZ5A 1X91A 1GKXA 4AI6A 3II9A 4U83A 3TZ2A 5K3JA 4AKGA 2FONA 1OAHA 1S26A 1SIRA 2BU2A 3DJLA 4XVXA 3D1IA 4MP7A 1X90A 1RJ1A 3GQTA 3C3LA 4JEKA 4JIZA 1XFYA 2ZAFA 2UXWA 3BNGA 4Q4UA 3TORA 1PK0A 4KSAA 4P79A 3NF4A 2EBFX 2RF7A 3F29A 4MP2A 2YYJA 3GM6A 3MMOA 4OO2A 1SK6A 2CJ4A 2F6LA 4FF4A 1R2JA 2IX5A 2QR4A 3OWMA 3D9GA 3B96A 2OJQA 2C0UA 5M4KA 1RP3A 2OEVA 2VIGA
chains in the Genus database with same CATH topology
1BUCA 2EBAA 4DOYA 3FCJA 2RDZA 3HWCA 3SXQA 3AFFA 2IX6A 1GU6A 1EGDA 2YYIA 3EONA 2YYMA 1QDBA 3D9EA 1FS8A 5K3HA 3MPIA 2C12A 3BNHA 4L3ZA 1UKWA 3D9DA 4Q1OA 3EOMA 4W9UA 3R7KA 3P4TA 4L1FA 4N5FA 2JIFA 2A1TA 4ZXVA 2R0MA 3UU9A 4IRNA 3RKHA 3FO3A 3MXLA 3OIBA 2DVLA 1U8VA 2OR0A 2OT4A 3SCEA 3M9VA 4Q17A 2DDHA 1RX0A 4M9AA 4KCFA 4ZYJA 1W07A 4X28A 1UDYA 1IS2A 3MKHA 4IV6A 4KTOA 4O5MA 3AFEA 1SIQA 1EGEA 3X0XA 1IVHA 1FS9A 3SWOA 3SF6A 2E81A 2E80A 3OWAA 1EGCA 2VR0A 2D29A 4P13A 4NXLA 4RM7A 4Q5CA 4WJYA 2JBSA 5K3GA 2REHA 3TTBA 2WBIA 2YYLA 2JBTA 3BNFA 1FS7A 4G5EA 2ZO5A 3X0YA 4Q5BA 3PFDA 2RFQA 3S7WA 1WS9A 2R0NA 3MDDA 3GNCA 4L38A 2YYKA 2YYGA 4L3XA 2CX9A 2Z1QA 3MDEA 3D6BA 4Q0TA 4HR3A 3LGQA 4L3YA 3L1TA 2PG0A 3LG1A 3UBRA 1T9GA 2J7AA 3D9FA 3MPJA 5K3IA 2JBRA 1JQIA 4X28C 3BNJA 3II9A 4U83A 5K3JA 2FONA 1OAHA 1SIRA 4XVXA 3D1IA 3GQTA 4JEKA 2ZAFA 2UXWA 3BNGA 4Q4UA 3TORA 3NF4A 2RF7A 3F29A 2YYJA 3GM6A 3MMOA 4OO2A 1R2JA 2IX5A 3OWMA 3D9GA 3B96A 2C0UA 2VIGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BUC A;  2EBA A;  4DOY A;  3FCJ A;  2RDZ A;  3HWC A;  3SXQ A;  3AFF A;  2IX6 A;  1GU6 A;  1EGD A;  2YYI A;  3EON A;  2YYM A;  1QDB A;  3D9E A;  1FS8 A;  5K3H A;  3MPI A;  2C12 A;  3BNH A;  4L3Z A;  1UKW A;  3D9D A;  4Q1O A;  3EOM A;  4W9U A;  3R7K A;  3P4T A;  4L1F A;  4N5F A;  2JIF A;  2A1T A;  4ZXV A;  2R0M A;  3UU9 A;  4IRN A;  3RKH A;  3FO3 A;  3MXL A;  3OIB A;  2DVL A;  1U8V A;  2OR0 A;  2OT4 A;  3SCE A;  3M9V A;  4Q17 A;  2DDH A;  1RX0 A;  4M9A A;  4KCF A;  4ZYJ A;  1W07 A;  4X28 A;  1UDY A;  1IS2 A;  3MKH A;  4IV6 A;  4KTO A;  4O5M A;  3AFE A;  1SIQ A;  1EGE A;  3X0X A;  1IVH A;  1FS9 A;  3SWO A;  3SF6 A;  2E81 A;  2E80 A;  3OWA A;  1EGC A;  2VR0 A;  2D29 A;  4P13 A;  4NXL A;  4RM7 A;  4Q5C A;  4WJY A;  2JBS A;  5K3G A;  2REH A;  3TTB A;  2WBI A;  2YYL A;  2JBT A;  3BNF A;  1FS7 A;  4G5E A;  2ZO5 A;  3X0Y A;  4Q5B A;  3PFD A;  2RFQ A;  3S7W A;  1WS9 A;  2R0N A;  3MDD A;  3GNC A;  4L38 A;  2YYK A;  2YYG A;  4L3X A;  2CX9 A;  2Z1Q A;  3MDE A;  3D6B A;  4Q0T A;  4HR3 A;  3LGQ A;  4L3Y A;  3L1T A;  2PG0 A;  3LG1 A;  3UBR A;  1T9G A;  2J7A A;  3D9F A;  3MPJ A;  5K3I A;  2JBR A;  1JQI A;  4X28 C;  3BNJ A;  3II9 A;  4U83 A;  5K3J A;  2FON A;  1OAH A;  1SIR A;  4XVX A;  3D1I A;  3GQT A;  4JEK A;  2ZAF A;  2UXW A;  3BNG A;  4Q4U A;  3TOR A;  3NF4 A;  2RF7 A;  3F29 A;  2YYJ A;  3GM6 A;  3MMO A;  4OO2 A;  1R2J A;  2IX5 A;  3OWM A;  3D9G A;  3B96 A;  2C0U A;  2VIG A; 
#chains in the Genus database with same CATH topology
 1Y0V A;  3KML A;  1BUC A;  2EBA A;  4DOY A;  1JM6 A;  2ZDX A;  4AKI A;  3U33 A;  3FCJ A;  1Y8N A;  3X29 A;  2RDZ A;  4MPE A;  3HWC A;  2BTZ A;  2XQR B;  3AFF A;  2AO2 A;  3SXQ A;  2IX6 A;  1GU6 A;  1EGD A;  2YYI A;  3EON A;  2YYM A;  4LQS B;  1QDB A;  3D9E A;  1RJ4 A;  1FS8 A;  5K3H A;  4FF2 A;  3MPI A;  2C12 A;  3BNH A;  4L3Z A;  2CJ8 A;  5B5V A;  1UKW A;  2BU8 A;  3D9D A;  4Q1O A;  3EOM A;  4W9U A;  4HKR A;  1XFX A;  2Q8H A;  3VKG A;  2LFW A;  3R7K A;  3P4T A;  2PO4 A;  4L1F A;  5J71 A;  5M4M A;  4N5F A;  1Y8O A;  2JIF A;  2A1T A;  3TZ4 A;  2R05 A;  1PI1 A;  1K93 A;  1R3B A;  2ZKJ A;  4H81 A;  2EBH X;  5BRK A;  4ZXV A;  2R0M A;  3UU9 A;  4IRN A;  1X8Z A;  1XFV A;  3FO3 A;  1XFZ A;  4MPN A;  3MXL A;  4JIO A;  3OIB A;  4V25 A;  3RKH A;  2DVL A;  1U8V A;  2OR0 A;  2E0A A;  2OT4 A;  3SCE A;  4E01 A;  3Q0A A;  3M9V A;  1XFW A;  2DDH A;  4Q17 A;  3Q24 A;  1RX0 A;  4M9A A;  4KCF A;  4ZYJ A;  1W07 A;  2BU6 A;  4E00 A;  1SC5 A;  4X28 A;  1UDY A;  5B6B A;  1IS2 A;  3MKH A;  4IV6 A;  4KTO A;  4O5M A;  4FF1 A;  2CJ7 A;  2OEX A;  3AFE A;  2Q8G A;  1SIQ A;  1EGE A;  3Q22 A;  3X0X A;  2CJ6 A;  5BRM A;  3VKH A;  1IVH A;  1GKZ A;  2HJN A;  5M4P A;  2XS1 A;  2CJ5 A;  1FS9 A;  3SWO A;  3SF6 A;  2VF1 A;  2E81 A;  4G97 A;  2E80 A;  4QIC A;  3OWA A;  1EGC A;  1K90 A;  5B5W A;  2AZE A;  2VR0 A;  2D29 A;  2R02 A;  4H85 A;  4P13 A;  4H7Q A;  4NXL A;  1K8T A;  4RM7 A;  2R03 A;  4Q5C A;  2JBS A;  5K3G A;  4WJY A;  3N0R A;  2REH A;  3TTB A;  3CRK A;  5J6A A;  2WBI A;  4FZ4 A;  2YYL A;  2JBT A;  3BNF A;  1FS7 A;  4G5E A;  4DZY A;  2ZO5 A;  2Q8I A;  3CRL A;  3X0Y A;  4Q5B A;  2Q8F A;  3VAD A;  1XG2 B;  3PFD A;  2RFQ A;  3S7W A;  1WS9 A;  2R0N A;  2BU7 A;  2GBB A;  3MDD A;  2BU5 A;  5GJV E;  4V26 A;  3GNC A;  2XS8 A;  2EC5 A;  4HKS A;  2YYK A;  3D2R A;  4L38 A;  2YYG A;  4L3X A;  2CX9 A;  4E02 A;  5M4N A;  3C46 A;  2Z1Q A;  3MDE A;  3D6B A;  3TZ0 A;  4Q0T A;  4HR3 A;  4MPC A;  3LGQ A;  4L3Y A;  4KS9 A;  3L1T A;  2PG0 A;  3LG1 A;  3UBR A;  1T9G A;  1GJV A;  1Y8P A;  2PNR A;  2FP1 A;  2J7A A;  3CE2 A;  4LQQ B;  4F0X A;  5EZ3 A;  3D9F A;  3MPJ A;  1LVC A;  2YGW A;  5K3I A;  4KSF A;  2JBR A;  5GJW E;  4J1V A;  3Q23 A;  1XFU A;  3C2P A;  4FF3 A;  1JQI A;  4X28 C;  2ZDY A;  3BNJ A;  4AKH A;  2FP2 A;  3TZ5 A;  1X91 A;  1GKX A;  4AI6 A;  3II9 A;  4U83 A;  3TZ2 A;  5K3J A;  4AKG A;  2FON A;  1OAH A;  1S26 A;  1SIR A;  2BU2 A;  3DJL A;  4XVX A;  3D1I A;  4MP7 A;  1X90 A;  1RJ1 A;  3GQT A;  3C3L A;  4JEK A;  4JIZ A;  1XFY A;  2ZAF A;  2UXW A;  3BNG A;  4Q4U A;  3TOR A;  1PK0 A;  4KSA A;  4P79 A;  3NF4 A;  2EBF X;  2RF7 A;  3F29 A;  4MP2 A;  2YYJ A;  3GM6 A;  3MMO A;  4OO2 A;  1SK6 A;  2CJ4 A;  2F6L A;  4FF4 A;  1R2J A;  2IX5 A;  2QR4 A;  3OWM A;  3D9G A;  3B96 A;  2OJQ A;  2C0U A;  5M4K A;  1RP3 A;  2OEV A;  2VIG A; 
#chains in the Genus database with same CATH homology
 1BUC A;  2EBA A;  4DOY A;  3FCJ A;  2RDZ A;  3HWC A;  3SXQ A;  3AFF A;  2IX6 A;  1GU6 A;  1EGD A;  2YYI A;  3EON A;  2YYM A;  1QDB A;  3D9E A;  1FS8 A;  5K3H A;  3MPI A;  2C12 A;  3BNH A;  4L3Z A;  1UKW A;  3D9D A;  4Q1O A;  3EOM A;  4W9U A;  3R7K A;  3P4T A;  4L1F A;  4N5F A;  2JIF A;  2A1T A;  4ZXV A;  2R0M A;  3UU9 A;  4IRN A;  3RKH A;  3FO3 A;  3MXL A;  3OIB A;  2DVL A;  1U8V A;  2OR0 A;  2OT4 A;  3SCE A;  3M9V A;  4Q17 A;  2DDH A;  1RX0 A;  4M9A A;  4KCF A;  4ZYJ A;  1W07 A;  4X28 A;  1UDY A;  1IS2 A;  3MKH A;  4IV6 A;  4KTO A;  4O5M A;  3AFE A;  1SIQ A;  1EGE A;  3X0X A;  1IVH A;  1FS9 A;  3SWO A;  3SF6 A;  2E81 A;  2E80 A;  3OWA A;  1EGC A;  2VR0 A;  2D29 A;  4P13 A;  4NXL A;  4RM7 A;  4Q5C A;  4WJY A;  2JBS A;  5K3G A;  2REH A;  3TTB A;  2WBI A;  2YYL A;  2JBT A;  3BNF A;  1FS7 A;  4G5E A;  2ZO5 A;  3X0Y A;  4Q5B A;  3PFD A;  2RFQ A;  3S7W A;  1WS9 A;  2R0N A;  3MDD A;  3GNC A;  4L38 A;  2YYK A;  2YYG A;  4L3X A;  2CX9 A;  2Z1Q A;  3MDE A;  3D6B A;  4Q0T A;  4HR3 A;  3LGQ A;  4L3Y A;  3L1T A;  2PG0 A;  3LG1 A;  3UBR A;  1T9G A;  2J7A A;  3D9F A;  3MPJ A;  5K3I A;  2JBR A;  1JQI A;  4X28 C;  3BNJ A;  3II9 A;  4U83 A;  5K3J A;  2FON A;  1OAH A;  1SIR A;  4XVX A;  3D1I A;  3GQT A;  4JEK A;  2ZAF A;  2UXW A;  3BNG A;  4Q4U A;  3TOR A;  3NF4 A;  2RF7 A;  3F29 A;  2YYJ A;  3GM6 A;  3MMO A;  4OO2 A;  1R2J A;  2IX5 A;  3OWM A;  3D9G A;  3B96 A;  2C0U A;  2VIG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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