2A1TA

Structure of the human mcad:etf e165betaa complex
Total Genus 145
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
145
sequence length
386
structure length
386
Chain Sequence
LGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDKYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase/electron transport
molecule keywords Acyl-CoA dehydrogenase, medium-chain specific, mitochondrial
publication title Stabilization of Non-productive Conformations Underpins Rapid Electron Transfer to Electron-transferring Flavoprotein
pubmed doi rcsb
source organism Homo sapiens
total genus 145
structure length 386
sequence length 386
chains with identical sequence B, C, D
ec nomenclature ec 1.3.8.7: Medium-chain acyl-CoA dehydrogenase.
pdb deposition date 2005-06-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 2a1tA01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 2a1tA03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 2a1tA02
3AFFA 4ZYJA 2CX9A 3BNJA 2EBAA 3II9A 1SIQA 4Q5BA 3D9DA 1OAHA 4Q0TA 1FS9A 1FS7A 2VIGA 2WBIA 4KCFA 3EONA 1QDBA 4G5EA 2YYIA 4P13A 4IV6A 1EGDA 2OT4A 4NXLA 4M9AA 2JIFA 2DVLA 4XVXA 3X0XA 3D9GA 3AFEA 3MXLA 4RM7A 4L3XA 1SIRA 4Q5CA 2PG0A 2REHA 2OR0A 1EGCA 4X28C 3LGQA 1BUCA 4U83A 1IS2A 1JQIA 3BNFA 4L38A 3R7KA 2Z1QA 3SXQA 2C0UA 2JBTA 3GQTA 2E80A 3BNGA 3MMOA 3P4TA 2J7AA 4Q4UA 3D9FA 3EOMA 2YYMA 3FO3A 2JBRA 4O5MA 1EGEA 3MPJA 2ZO5A 3NF4A 1R2JA 2E81A 3B96A 3MKHA 3SF6A 3D6BA 3MDDA 2UXWA 3GNCA 5K3HA 1T9GA 4L3ZA 3BNHA 4DOYA 3D9EA 4IRNA 3LG1A 4JEKA 2R0MA 1UDYA 3X0YA 3GM6A 3UBRA 1U8VA 4Q1OA 3PFDA 1IVHA 5K3JA 3SWOA 4HR3A 3OWAA 1UKWA 2YYGA 1GU6A 1FS8A 1W07A 4N5FA 2R0NA 2FONA 2DDHA 3MPIA 4KTOA 3TTBA 4L1FA 3RKHA 4W9UA 2JBSA 2D29A 4X28A 3SCEA 5K3IA 3S7WA 2ZAFA 3D1IA 1WS9A 2IX5A 3L1TA 3TORA 2RDZA 2RFQA 3HWCA 3M9VA 2A1TA 4WJYA 4OO2A 1RX0A 3F29A 2IX6A 5K3GA 3UU9A 4L3YA 2YYJA 2C12A 2YYLA 3FCJA 2RF7A 3OWMA 4Q17A 4ZXVA 2VR0A 2YYKA 3OIBA 3MDEA
chains in the Genus database with same CATH superfamily
3AFFA 2BTZA 4ZYJA 1XFYA 2CX9A 3BNJA 2EBAA 3II9A 1SIQA 4Q5BA 1K90A 1K8TA 4E01A 2AO2A 4HKRA 3D9DA 1OAHA 1Y0VA 3N0RA 4Q0TA 4KSAA 1FS9A 1FS7A 1GKXA 2LFWA 2YGWA 3CRKA 2VIGA 2WBIA 4G97A 3C2PA 4KCFA 3EONA 1QDBA 4V26A 4G5EA 2QR4A 2YYIA 4P13A 4IV6A 1EGDA 2OT4A 4NXLA 4M9AA 2JIFA 1GJVA 5M4NA 2DVLA 4XVXA 5BRMA 3X0XA 2BU7A 3D9GA 3AFEA 1PI1A 3MXLA 4RM7A 2E0AA 4L3XA 5B6BA 1R3BA 1SIRA 1X90A 2BU2A 4J1VA 4FF2A 3VKHA 4Q5CA 4E00A 2PG0A 2BU8A 4AKIA 2AZEA 4JIOA 2REHA 1XFVA 2EC5A 2GBBA 1S26A 2OR0A 3Q0AA 2R03A 4H7QA 3Q24A 4FZ4A 1EGCA 4X28C 2R05A 3LGQA 4MPNA 1BUCA 5EZ3A 2EBFX 4U83A 1IS2A 2CJ5A 1SK6A 4QICA 1K93A 3U33A 1JQIA 3BNFA 4L38A 1PK0A 3R7KA 1LVCA 2Z1QA 3SXQA 2C0UA 4F0XA 2JBTA 3D2RA 4FF4A 4V25A 3GQTA 2E80A 3BNGA 2Q8GA 3MMOA 3P4TA 2J7AA 4Q4UA 1SC5A 3D9FA 5M4PA 4H85A 1Y8PA 2XQRB 3EOMA 2OEVA 3KMLA 5M4MA 2YYMA 4FF1A 1Y8OA 1XG2B 2PNRA 3FO3A 2JBRA 4O5MA 1EGEA 3CRLA 3MPJA 2ZO5A 5M4KA 4H81A 3NF4A 4KSFA 1R2JA 2E81A 4FF3A 3C46A 4AKHA 3B96A 3MKHA 4KS9A 5B5VA 2ZDYA 2ZDXA 3SF6A 3D6BA 2BU5A 3MDDA 2CJ6A 2UXWA 3GNCA 2FP2A 3X29A 2HJNA 1RJ1A 5K3HA 1T9GA 2XS1A 2CJ8A 4L3ZA 4LQQB 4MP7A 2OEXA 3BNHA 2Q8IA 4DOYA 3D9EA 3TZ5A 1XFXA 4IRNA 1RP3A 3LG1A 4JEKA 2R0MA 4E02A 1UDYA 3X0YA 4MPCA 3GM6A 3UBRA 1U8VA 4Q1OA 3PFDA 1IVHA 5K3JA 3SWOA 4HR3A 3OWAA 1UKWA 2YYGA 1GU6A 1FS8A 1W07A 2OJQA 2F6LA 4HKSA 5GJWE 3VADA 5J6AA 4N5FA 2R02A 2R0NA 2FONA 2DDHA 3MPIA 4LQSB 1RJ4A 2XS8A 4P79A 5GJVE 4KTOA 4JIZA 3TTBA 1Y8NA 4L1FA 4MP2A 4DZYA 1XFWA 4W9UA 2Q8HA 3RKHA 2JBSA 2D29A 4X28A 3SCEA 5K3IA 3VKGA 3S7WA 2ZAFA 2FP1A 3CE2A 4AI6A 2EBHX 2PO4A 2ZKJA 1WS9A 2IX5A 3D1IA 3L1TA 3TORA 5J71A 2RDZA 2RFQA 2CJ4A 2Q8FA 3HWCA 3Q22A 1XFUA 3Q23A 3C3LA 3TZ4A 2VF1A 1JM6A 3M9VA 2A1TA 4WJYA 4OO2A 2CJ7A 1RX0A 5B5WA 4AKGA 3F29A 2IX6A 5K3GA 3TZ0A 3DJLA 3UU9A 4L3YA 1XFZA 2BU6A 3TZ2A 4MPEA 2YYJA 2C12A 1GKZA 2YYLA 3FCJA 2RF7A 1X91A 3OWMA 4ZXVA 2VR0A 2YYKA 3OIBA 1X8ZA 4Q17A 5BRKA 3MDEA
chains in the Genus database with same CATH topology
3AFFA 4ZYJA 2CX9A 3BNJA 2EBAA 3II9A 1SIQA 4Q5BA 3D9DA 1OAHA 4Q0TA 1FS9A 1FS7A 2VIGA 2WBIA 4KCFA 3EONA 1QDBA 4G5EA 2YYIA 4P13A 4IV6A 1EGDA 2OT4A 4NXLA 4M9AA 2JIFA 2DVLA 4XVXA 3X0XA 3D9GA 3AFEA 3MXLA 4RM7A 4L3XA 1SIRA 4Q5CA 2PG0A 2REHA 2OR0A 1EGCA 4X28C 3LGQA 1BUCA 4U83A 1IS2A 1JQIA 3BNFA 4L38A 3R7KA 2Z1QA 3SXQA 2C0UA 2JBTA 3GQTA 2E80A 3BNGA 3MMOA 3P4TA 2J7AA 4Q4UA 3D9FA 3EOMA 2YYMA 3FO3A 2JBRA 4O5MA 1EGEA 3MPJA 2ZO5A 3NF4A 1R2JA 2E81A 3B96A 3MKHA 3SF6A 3D6BA 3MDDA 2UXWA 3GNCA 5K3HA 1T9GA 4L3ZA 3BNHA 4DOYA 3D9EA 4IRNA 3LG1A 4JEKA 2R0MA 1UDYA 3X0YA 3GM6A 3UBRA 1U8VA 4Q1OA 3PFDA 1IVHA 5K3JA 3SWOA 4HR3A 3OWAA 1UKWA 2YYGA 1GU6A 1FS8A 1W07A 4N5FA 2R0NA 2FONA 2DDHA 3MPIA 4KTOA 3TTBA 4L1FA 3RKHA 4W9UA 2JBSA 2D29A 4X28A 3SCEA 5K3IA 3S7WA 2ZAFA 3D1IA 1WS9A 2IX5A 3L1TA 3TORA 2RDZA 2RFQA 3HWCA 3M9VA 2A1TA 4WJYA 4OO2A 1RX0A 3F29A 2IX6A 5K3GA 3UU9A 4L3YA 2YYJA 2C12A 2YYLA 3FCJA 2RF7A 3OWMA 4Q17A 4ZXVA 2VR0A 2YYKA 3OIBA 3MDEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AFF A;  4ZYJ A;  2CX9 A;  3BNJ A;  2EBA A;  3II9 A;  1SIQ A;  4Q5B A;  3D9D A;  1OAH A;  4Q0T A;  1FS9 A;  1FS7 A;  2VIG A;  2WBI A;  4KCF A;  3EON A;  1QDB A;  4G5E A;  2YYI A;  4P13 A;  4IV6 A;  1EGD A;  2OT4 A;  4NXL A;  4M9A A;  2JIF A;  2DVL A;  4XVX A;  3X0X A;  3D9G A;  3AFE A;  3MXL A;  4RM7 A;  4L3X A;  1SIR A;  4Q5C A;  2PG0 A;  2REH A;  2OR0 A;  1EGC A;  4X28 C;  3LGQ A;  1BUC A;  4U83 A;  1IS2 A;  1JQI A;  3BNF A;  4L38 A;  3R7K A;  2Z1Q A;  3SXQ A;  2C0U A;  2JBT A;  3GQT A;  2E80 A;  3BNG A;  3MMO A;  3P4T A;  2J7A A;  4Q4U A;  3D9F A;  3EOM A;  2YYM A;  3FO3 A;  2JBR A;  4O5M A;  1EGE A;  3MPJ A;  2ZO5 A;  3NF4 A;  1R2J A;  2E81 A;  3B96 A;  3MKH A;  3SF6 A;  3D6B A;  3MDD A;  2UXW A;  3GNC A;  5K3H A;  1T9G A;  4L3Z A;  3BNH A;  4DOY A;  3D9E A;  4IRN A;  3LG1 A;  4JEK A;  2R0M A;  1UDY A;  3X0Y A;  3GM6 A;  3UBR A;  1U8V A;  4Q1O A;  3PFD A;  1IVH A;  5K3J A;  3SWO A;  4HR3 A;  3OWA A;  1UKW A;  2YYG A;  1GU6 A;  1FS8 A;  1W07 A;  4N5F A;  2R0N A;  2FON A;  2DDH A;  3MPI A;  4KTO A;  3TTB A;  4L1F A;  3RKH A;  4W9U A;  2JBS A;  2D29 A;  4X28 A;  3SCE A;  5K3I A;  3S7W A;  2ZAF A;  3D1I A;  1WS9 A;  2IX5 A;  3L1T A;  3TOR A;  2RDZ A;  2RFQ A;  3HWC A;  3M9V A;  2A1T A;  4WJY A;  4OO2 A;  1RX0 A;  3F29 A;  2IX6 A;  5K3G A;  3UU9 A;  4L3Y A;  2YYJ A;  2C12 A;  2YYL A;  3FCJ A;  2RF7 A;  3OWM A;  4Q17 A;  4ZXV A;  2VR0 A;  2YYK A;  3OIB A;  3MDE A; 
#chains in the Genus database with same CATH topology
 3AFF A;  2BTZ A;  4ZYJ A;  1XFY A;  2CX9 A;  3BNJ A;  2EBA A;  3II9 A;  1SIQ A;  4Q5B A;  1K90 A;  1K8T A;  4E01 A;  2AO2 A;  4HKR A;  3D9D A;  1OAH A;  1Y0V A;  3N0R A;  4Q0T A;  4KSA A;  1FS9 A;  1FS7 A;  1GKX A;  2LFW A;  2YGW A;  3CRK A;  2VIG A;  2WBI A;  4G97 A;  3C2P A;  4KCF A;  3EON A;  1QDB A;  4V26 A;  4G5E A;  2QR4 A;  2YYI A;  4P13 A;  4IV6 A;  1EGD A;  2OT4 A;  4NXL A;  4M9A A;  2JIF A;  1GJV A;  5M4N A;  2DVL A;  4XVX A;  5BRM A;  3X0X A;  2BU7 A;  3D9G A;  3AFE A;  1PI1 A;  3MXL A;  4RM7 A;  2E0A A;  4L3X A;  5B6B A;  1R3B A;  1SIR A;  1X90 A;  2BU2 A;  4J1V A;  4FF2 A;  3VKH A;  4Q5C A;  4E00 A;  2PG0 A;  2BU8 A;  4AKI A;  2AZE A;  4JIO A;  2REH A;  1XFV A;  2EC5 A;  2GBB A;  1S26 A;  2OR0 A;  3Q0A A;  2R03 A;  4H7Q A;  3Q24 A;  4FZ4 A;  1EGC A;  4X28 C;  2R05 A;  3LGQ A;  4MPN A;  1BUC A;  5EZ3 A;  2EBF X;  4U83 A;  1IS2 A;  2CJ5 A;  1SK6 A;  4QIC A;  1K93 A;  3U33 A;  1JQI A;  3BNF A;  4L38 A;  1PK0 A;  3R7K A;  1LVC A;  2Z1Q A;  3SXQ A;  2C0U A;  4F0X A;  2JBT A;  3D2R A;  4FF4 A;  4V25 A;  3GQT A;  2E80 A;  3BNG A;  2Q8G A;  3MMO A;  3P4T A;  2J7A A;  4Q4U A;  1SC5 A;  3D9F A;  5M4P A;  4H85 A;  1Y8P A;  2XQR B;  3EOM A;  2OEV A;  3KML A;  5M4M A;  2YYM A;  4FF1 A;  1Y8O A;  1XG2 B;  2PNR A;  3FO3 A;  2JBR A;  4O5M A;  1EGE A;  3CRL A;  3MPJ A;  2ZO5 A;  5M4K A;  4H81 A;  3NF4 A;  4KSF A;  1R2J A;  2E81 A;  4FF3 A;  3C46 A;  4AKH A;  3B96 A;  3MKH A;  4KS9 A;  5B5V A;  2ZDY A;  2ZDX A;  3SF6 A;  3D6B A;  2BU5 A;  3MDD A;  2CJ6 A;  2UXW A;  3GNC A;  2FP2 A;  3X29 A;  2HJN A;  1RJ1 A;  5K3H A;  1T9G A;  2XS1 A;  2CJ8 A;  4L3Z A;  4LQQ B;  4MP7 A;  2OEX A;  3BNH A;  2Q8I A;  4DOY A;  3D9E A;  3TZ5 A;  1XFX A;  4IRN A;  1RP3 A;  3LG1 A;  4JEK A;  2R0M A;  4E02 A;  1UDY A;  3X0Y A;  4MPC A;  3GM6 A;  3UBR A;  1U8V A;  4Q1O A;  3PFD A;  1IVH A;  5K3J A;  3SWO A;  4HR3 A;  3OWA A;  1UKW A;  2YYG A;  1GU6 A;  1FS8 A;  1W07 A;  2OJQ A;  2F6L A;  4HKS A;  5GJW E;  3VAD A;  5J6A A;  4N5F A;  2R02 A;  2R0N A;  2FON A;  2DDH A;  3MPI A;  4LQS B;  1RJ4 A;  2XS8 A;  4P79 A;  5GJV E;  4KTO A;  4JIZ A;  3TTB A;  1Y8N A;  4L1F A;  4MP2 A;  4DZY A;  1XFW A;  4W9U A;  2Q8H A;  3RKH A;  2JBS A;  2D29 A;  4X28 A;  3SCE A;  5K3I A;  3VKG A;  3S7W A;  2ZAF A;  2FP1 A;  3CE2 A;  4AI6 A;  2EBH X;  2PO4 A;  2ZKJ A;  1WS9 A;  2IX5 A;  3D1I A;  3L1T A;  3TOR A;  5J71 A;  2RDZ A;  2RFQ A;  2CJ4 A;  2Q8F A;  3HWC A;  3Q22 A;  1XFU A;  3Q23 A;  3C3L A;  3TZ4 A;  2VF1 A;  1JM6 A;  3M9V A;  2A1T A;  4WJY A;  4OO2 A;  2CJ7 A;  1RX0 A;  5B5W A;  4AKG A;  3F29 A;  2IX6 A;  5K3G A;  3TZ0 A;  3DJL A;  3UU9 A;  4L3Y A;  1XFZ A;  2BU6 A;  3TZ2 A;  4MPE A;  2YYJ A;  2C12 A;  1GKZ A;  2YYL A;  3FCJ A;  2RF7 A;  1X91 A;  3OWM A;  4ZXV A;  2VR0 A;  2YYK A;  3OIB A;  1X8Z A;  4Q17 A;  5BRK A;  3MDE A; 
#chains in the Genus database with same CATH homology
 3AFF A;  4ZYJ A;  2CX9 A;  3BNJ A;  2EBA A;  3II9 A;  1SIQ A;  4Q5B A;  3D9D A;  1OAH A;  4Q0T A;  1FS9 A;  1FS7 A;  2VIG A;  2WBI A;  4KCF A;  3EON A;  1QDB A;  4G5E A;  2YYI A;  4P13 A;  4IV6 A;  1EGD A;  2OT4 A;  4NXL A;  4M9A A;  2JIF A;  2DVL A;  4XVX A;  3X0X A;  3D9G A;  3AFE A;  3MXL A;  4RM7 A;  4L3X A;  1SIR A;  4Q5C A;  2PG0 A;  2REH A;  2OR0 A;  1EGC A;  4X28 C;  3LGQ A;  1BUC A;  4U83 A;  1IS2 A;  1JQI A;  3BNF A;  4L38 A;  3R7K A;  2Z1Q A;  3SXQ A;  2C0U A;  2JBT A;  3GQT A;  2E80 A;  3BNG A;  3MMO A;  3P4T A;  2J7A A;  4Q4U A;  3D9F A;  3EOM A;  2YYM A;  3FO3 A;  2JBR A;  4O5M A;  1EGE A;  3MPJ A;  2ZO5 A;  3NF4 A;  1R2J A;  2E81 A;  3B96 A;  3MKH A;  3SF6 A;  3D6B A;  3MDD A;  2UXW A;  3GNC A;  5K3H A;  1T9G A;  4L3Z A;  3BNH A;  4DOY A;  3D9E A;  4IRN A;  3LG1 A;  4JEK A;  2R0M A;  1UDY A;  3X0Y A;  3GM6 A;  3UBR A;  1U8V A;  4Q1O A;  3PFD A;  1IVH A;  5K3J A;  3SWO A;  4HR3 A;  3OWA A;  1UKW A;  2YYG A;  1GU6 A;  1FS8 A;  1W07 A;  4N5F A;  2R0N A;  2FON A;  2DDH A;  3MPI A;  4KTO A;  3TTB A;  4L1F A;  3RKH A;  4W9U A;  2JBS A;  2D29 A;  4X28 A;  3SCE A;  5K3I A;  3S7W A;  2ZAF A;  3D1I A;  1WS9 A;  2IX5 A;  3L1T A;  3TOR A;  2RDZ A;  2RFQ A;  3HWC A;  3M9V A;  2A1T A;  4WJY A;  4OO2 A;  1RX0 A;  3F29 A;  2IX6 A;  5K3G A;  3UU9 A;  4L3Y A;  2YYJ A;  2C12 A;  2YYL A;  3FCJ A;  2RF7 A;  3OWM A;  4Q17 A;  4ZXV A;  2VR0 A;  2YYK A;  3OIB A;  3MDE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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