4HR3A

Structure of a putative acyl-coa dehydrogenase from mycobacterium abscessus
Total Genus 145
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
145
sequence length
407
structure length
407
Chain Sequence
FAPSARAAELIAAVREFIDAEVMPVERAVLAHHDELLGARAGTTAELWHVPPELDSLKAKARAAGLWNLFLPDPELGGGLSNSEYAPLAEQMGRSLFAPTVFNCNAPDSGNMEVLHRYGSQEQKEVWLEPLLEGDIRSAFCMTEPDVASSDATNMAATAVVEGDEVVINGRKWWSTGVGHPDCKVIIFMGLTDPNAHRYARHSMVLVPMDTPGITVERMLPTMGFYDEPGGHGVVSFDNVRLPADAFIAGPGKGFEIAQGRLGPGRVHHAMRLIGLAEVALEHACRRGLDRTAFGKPLVNLGGNRERIADARIAINQTRLLVLHAAWLLDTVGIMGALSAVSEIKVAAPNMAQQVIDMAIQIHGGGGLSNDFPLAAAWVNARALRLADGPDEVHRGVVARIELAKYA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Increasing the structural coverage of tuberculosis drug targets.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Mycobacterium abscessus
molecule keywords Putative acyl-CoA dehydrogenase
total genus 145
structure length 407
sequence length 407
ec nomenclature
pdb deposition date 2012-10-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 4hr3A01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 4hr3A03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 4hr3A02
3FCJA 4ZXVA 2C0UA 3PFDA 1RX0A 3EONA 4HR3A 1WS9A 2ZAFA 3SF6A 1FS9A 4L3ZA 2REHA 3D9DA 4KTOA 4JEKA 2E80A 3D9FA 3TTBA 2JBSA 3S7WA 1BUCA 3UBRA 4Q5CA 3X0YA 3LG1A 2IX5A 2C12A 2FONA 2D29A 2R0MA 4KCFA 3L1TA 1QDBA 2E81A 2OR0A 4Q5BA 2YYKA 3GQTA 3MKHA 4RM7A 3II9A 3BNGA 3MPJA 1EGDA 4L38A 2RFQA 3MDEA 3UU9A 4XVXA 3BNJA 2YYIA 1R2JA 4O5MA 3GNCA 3HWCA 2WBIA 1FS7A 5K3JA 3EOMA 2R0NA 1EGCA 3OWAA 4IV6A 2DDHA 4U83A 4Q1OA 2J7AA 3GM6A 1EGEA 2VR0A 3OIBA 3P4TA 3BNFA 4Q4UA 3MXLA 1SIQA 4L1FA 1GU6A 2JIFA 2ZO5A 4Q17A 2DVLA 1FS8A 3SWOA 4WJYA 4OO2A 3MDDA 5K3IA 3LGQA 2RF7A 2PG0A 3D9EA 1OAHA 1T9GA 2JBRA 4L3XA 4IRNA 3B96A 1JQIA 2YYLA 2UXWA 3D6BA 3D1IA 2IX6A 4ZYJA 2CX9A 2JBTA 2YYGA 2VIGA 1W07A 4Q0TA 1SIRA 5K3GA 4NXLA 3MMOA 3BNHA 3AFFA 2OT4A 3RKHA 1IVHA 4L3YA 1UKWA 1U8VA 1IS2A 4X28A 3M9VA 3FO3A 5K3HA 3TORA 3NF4A 2Z1QA 4X28C 2A1TA 4N5FA 3MPIA 3F29A 4M9AA 3SXQA 2RDZA 4G5EA 2EBAA 4DOYA 3D9GA 3AFEA 4W9UA 3X0XA 4P13A 3OWMA 1UDYA 2YYJA 3SCEA 3R7KA 2YYMA
chains in the Genus database with same CATH superfamily
4HKRA 3FCJA 2EBHX 4ZXVA 2C0UA 3PFDA 2VF1A 3D2RA 1RX0A 4G97A 3EONA 2PNRA 5GJWE 5M4PA 4HR3A 1WS9A 3Q22A 1XFZA 2ZAFA 3Q0AA 3SF6A 5M4KA 1FS9A 1XFUA 3TZ4A 4L3ZA 2CJ8A 1JM6A 2REHA 3D9DA 2XS8A 4FZ4A 4KTOA 4JEKA 3TZ2A 4H81A 1XFYA 2CJ6A 2E80A 2E0AA 3D9FA 2ZKJA 2JBSA 3N0RA 5B5VA 3S7WA 1BUCA 3TTBA 3UBRA 4Q5CA 3X0YA 2OJQA 3LG1A 2IX5A 4KSFA 4MPNA 2C12A 1K90A 2FONA 2D29A 2R0MA 4KCFA 2CJ5A 2FP2A 3L1TA 1QDBA 2E81A 4FF1A 4MPCA 2AO2A 2OR0A 4Q5BA 2OEXA 2YYKA 2Q8FA 4QICA 3GQTA 3MKHA 4RM7A 3TZ5A 1Y8PA 3U33A 3II9A 3BNGA 3MPJA 1EGDA 4L38A 2RFQA 2HJNA 3MDEA 1Y8OA 3UU9A 4XVXA 1X90A 4F0XA 3BNJA 2YYIA 2ZDXA 3CRKA 4MP7A 1R2JA 4O5MA 2Q8GA 4MP2A 1S26A 3GNCA 3HWCA 1X91A 2WBIA 1FS7A 2XQRB 5K3JA 3EOMA 2R0NA 1EGCA 3OWAA 4IV6A 2DDHA 2CJ4A 4U83A 1Y0VA 5J71A 4Q1OA 2J7AA 3GM6A 4JIZA 1RJ1A 1EGEA 1GKZA 5GJVE 2VR0A 3OIBA 3P4TA 3BNFA 4HKSA 5M4NA 4Q4UA 3MXLA 1XFWA 1SIQA 1PK0A 4AKGA 2XS1A 4L1FA 1GU6A 1PI1A 2JIFA 5B6BA 3VKHA 1X8ZA 2ZO5A 2ZDYA 2LFWA 2DVLA 4Q17A 4V25A 2QR4A 2OEVA 2BU2A 1FS8A 3DJLA 3SWOA 4WJYA 4E02A 1SC5A 3KMLA 4OO2A 4AKHA 2BU7A 3MDDA 5K3IA 2F6LA 3LGQA 2BTZA 1GKXA 2BU6A 2RF7A 5BRKA 2PG0A 3D9EA 1OAHA 1T9GA 2JBRA 4FF3A 2EC5A 4L3XA 4IRNA 3VADA 3B96A 5J6AA 1JQIA 2GBBA 2YYLA 2Q8HA 2UXWA 3D6BA 2BU5A 3D1IA 2IX6A 4ZYJA 2CX9A 4FF2A 2R02A 2JBTA 2YYGA 3CRLA 2VIGA 1W07A 4P79A 5BRMA 4Q0TA 1SIRA 5K3GA 4NXLA 3MMOA 3BNHA 3C2PA 3AFFA 2OT4A 2R05A 1K93A 4H7QA 4AI6A 4H85A 3RKHA 1IVHA 4JIOA 4L3YA 5B5WA 1UKWA 2FP1A 4LQQB 4E01A 4J1VA 1U8VA 1IS2A 2PO4A 4X28A 2AZEA 4DZYA 3M9VA 3FO3A 5M4MA 4LQSB 3C3LA 4AKIA 5K3HA 4KSAA 3TORA 4E00A 3C46A 3NF4A 1GJVA 4MPEA 3TZ0A 2Z1QA 4X28C 2A1TA 1RP3A 4FF4A 3CE2A 4N5FA 1SK6A 3MPIA 2BU8A 1K8TA 1R3BA 3F29A 2Q8IA 4M9AA 1XFXA 1LVCA 3SXQA 3X29A 3VKGA 2RDZA 2CJ7A 2YGWA 1Y8NA 2EBAA 4DOYA 3D9GA 3AFEA 4W9UA 1XG2B 4G5EA 3Q23A 5EZ3A 3X0XA 4P13A 1RJ4A 3OWMA 1UDYA 2YYJA 2EBFX 2R03A 1XFVA 3SCEA 4KS9A 3R7KA 3Q24A 2YYMA 4V26A
chains in the Genus database with same CATH topology
3FCJA 4ZXVA 2C0UA 3PFDA 1RX0A 3EONA 4HR3A 1WS9A 2ZAFA 3SF6A 1FS9A 4L3ZA 2REHA 3D9DA 4KTOA 4JEKA 2E80A 3D9FA 3TTBA 2JBSA 3S7WA 1BUCA 3UBRA 4Q5CA 3X0YA 3LG1A 2IX5A 2C12A 2FONA 2D29A 2R0MA 4KCFA 3L1TA 1QDBA 2E81A 2OR0A 4Q5BA 2YYKA 3GQTA 3MKHA 4RM7A 3II9A 3BNGA 3MPJA 1EGDA 4L38A 2RFQA 3MDEA 3UU9A 4XVXA 3BNJA 2YYIA 1R2JA 4O5MA 3GNCA 3HWCA 2WBIA 1FS7A 5K3JA 3EOMA 2R0NA 1EGCA 3OWAA 4IV6A 2DDHA 4U83A 4Q1OA 2J7AA 3GM6A 1EGEA 2VR0A 3OIBA 3P4TA 3BNFA 4Q4UA 3MXLA 1SIQA 4L1FA 1GU6A 2JIFA 2ZO5A 4Q17A 2DVLA 1FS8A 3SWOA 4WJYA 4OO2A 3MDDA 5K3IA 3LGQA 2RF7A 2PG0A 3D9EA 1OAHA 1T9GA 2JBRA 4L3XA 4IRNA 3B96A 1JQIA 2YYLA 2UXWA 3D6BA 3D1IA 2IX6A 4ZYJA 2CX9A 2JBTA 2YYGA 2VIGA 1W07A 4Q0TA 1SIRA 5K3GA 4NXLA 3MMOA 3BNHA 3AFFA 2OT4A 3RKHA 1IVHA 4L3YA 1UKWA 1U8VA 1IS2A 4X28A 3M9VA 3FO3A 5K3HA 3TORA 3NF4A 2Z1QA 4X28C 2A1TA 4N5FA 3MPIA 3F29A 4M9AA 3SXQA 2RDZA 4G5EA 2EBAA 4DOYA 3D9GA 3AFEA 4W9UA 3X0XA 4P13A 3OWMA 1UDYA 2YYJA 3SCEA 3R7KA 2YYMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FCJ A;  4ZXV A;  2C0U A;  3PFD A;  1RX0 A;  3EON A;  4HR3 A;  1WS9 A;  2ZAF A;  3SF6 A;  1FS9 A;  4L3Z A;  2REH A;  3D9D A;  4KTO A;  4JEK A;  2E80 A;  3D9F A;  3TTB A;  2JBS A;  3S7W A;  1BUC A;  3UBR A;  4Q5C A;  3X0Y A;  3LG1 A;  2IX5 A;  2C12 A;  2FON A;  2D29 A;  2R0M A;  4KCF A;  3L1T A;  1QDB A;  2E81 A;  2OR0 A;  4Q5B A;  2YYK A;  3GQT A;  3MKH A;  4RM7 A;  3II9 A;  3BNG A;  3MPJ A;  1EGD A;  4L38 A;  2RFQ A;  3MDE A;  3UU9 A;  4XVX A;  3BNJ A;  2YYI A;  1R2J A;  4O5M A;  3GNC A;  3HWC A;  2WBI A;  1FS7 A;  5K3J A;  3EOM A;  2R0N A;  1EGC A;  3OWA A;  4IV6 A;  2DDH A;  4U83 A;  4Q1O A;  2J7A A;  3GM6 A;  1EGE A;  2VR0 A;  3OIB A;  3P4T A;  3BNF A;  4Q4U A;  3MXL A;  1SIQ A;  4L1F A;  1GU6 A;  2JIF A;  2ZO5 A;  4Q17 A;  2DVL A;  1FS8 A;  3SWO A;  4WJY A;  4OO2 A;  3MDD A;  5K3I A;  3LGQ A;  2RF7 A;  2PG0 A;  3D9E A;  1OAH A;  1T9G A;  2JBR A;  4L3X A;  4IRN A;  3B96 A;  1JQI A;  2YYL A;  2UXW A;  3D6B A;  3D1I A;  2IX6 A;  4ZYJ A;  2CX9 A;  2JBT A;  2YYG A;  2VIG A;  1W07 A;  4Q0T A;  1SIR A;  5K3G A;  4NXL A;  3MMO A;  3BNH A;  3AFF A;  2OT4 A;  3RKH A;  1IVH A;  4L3Y A;  1UKW A;  1U8V A;  1IS2 A;  4X28 A;  3M9V A;  3FO3 A;  5K3H A;  3TOR A;  3NF4 A;  2Z1Q A;  4X28 C;  2A1T A;  4N5F A;  3MPI A;  3F29 A;  4M9A A;  3SXQ A;  2RDZ A;  4G5E A;  2EBA A;  4DOY A;  3D9G A;  3AFE A;  4W9U A;  3X0X A;  4P13 A;  3OWM A;  1UDY A;  2YYJ A;  3SCE A;  3R7K A;  2YYM A; 
#chains in the Genus database with same CATH topology
 4HKR A;  3FCJ A;  2EBH X;  4ZXV A;  2C0U A;  3PFD A;  2VF1 A;  3D2R A;  1RX0 A;  4G97 A;  3EON A;  2PNR A;  5GJW E;  5M4P A;  4HR3 A;  1WS9 A;  3Q22 A;  1XFZ A;  2ZAF A;  3Q0A A;  3SF6 A;  5M4K A;  1FS9 A;  1XFU A;  3TZ4 A;  4L3Z A;  2CJ8 A;  1JM6 A;  2REH A;  3D9D A;  2XS8 A;  4FZ4 A;  4KTO A;  4JEK A;  3TZ2 A;  4H81 A;  1XFY A;  2CJ6 A;  2E80 A;  2E0A A;  3D9F A;  2ZKJ A;  2JBS A;  3N0R A;  5B5V A;  3S7W A;  1BUC A;  3TTB A;  3UBR A;  4Q5C A;  3X0Y A;  2OJQ A;  3LG1 A;  2IX5 A;  4KSF A;  4MPN A;  2C12 A;  1K90 A;  2FON A;  2D29 A;  2R0M A;  4KCF A;  2CJ5 A;  2FP2 A;  3L1T A;  1QDB A;  2E81 A;  4FF1 A;  4MPC A;  2AO2 A;  2OR0 A;  4Q5B A;  2OEX A;  2YYK A;  2Q8F A;  4QIC A;  3GQT A;  3MKH A;  4RM7 A;  3TZ5 A;  1Y8P A;  3U33 A;  3II9 A;  3BNG A;  3MPJ A;  1EGD A;  4L38 A;  2RFQ A;  2HJN A;  3MDE A;  1Y8O A;  3UU9 A;  4XVX A;  1X90 A;  4F0X A;  3BNJ A;  2YYI A;  2ZDX A;  3CRK A;  4MP7 A;  1R2J A;  4O5M A;  2Q8G A;  4MP2 A;  1S26 A;  3GNC A;  3HWC A;  1X91 A;  2WBI A;  1FS7 A;  2XQR B;  5K3J A;  3EOM A;  2R0N A;  1EGC A;  3OWA A;  4IV6 A;  2DDH A;  2CJ4 A;  4U83 A;  1Y0V A;  5J71 A;  4Q1O A;  2J7A A;  3GM6 A;  4JIZ A;  1RJ1 A;  1EGE A;  1GKZ A;  5GJV E;  2VR0 A;  3OIB A;  3P4T A;  3BNF A;  4HKS A;  5M4N A;  4Q4U A;  3MXL A;  1XFW A;  1SIQ A;  1PK0 A;  4AKG A;  2XS1 A;  4L1F A;  1GU6 A;  1PI1 A;  2JIF A;  5B6B A;  3VKH A;  1X8Z A;  2ZO5 A;  2ZDY A;  2LFW A;  2DVL A;  4Q17 A;  4V25 A;  2QR4 A;  2OEV A;  2BU2 A;  1FS8 A;  3DJL A;  3SWO A;  4WJY A;  4E02 A;  1SC5 A;  3KML A;  4OO2 A;  4AKH A;  2BU7 A;  3MDD A;  5K3I A;  2F6L A;  3LGQ A;  2BTZ A;  1GKX A;  2BU6 A;  2RF7 A;  5BRK A;  2PG0 A;  3D9E A;  1OAH A;  1T9G A;  2JBR A;  4FF3 A;  2EC5 A;  4L3X A;  4IRN A;  3VAD A;  3B96 A;  5J6A A;  1JQI A;  2GBB A;  2YYL A;  2Q8H A;  2UXW A;  3D6B A;  2BU5 A;  3D1I A;  2IX6 A;  4ZYJ A;  2CX9 A;  4FF2 A;  2R02 A;  2JBT A;  2YYG A;  3CRL A;  2VIG A;  1W07 A;  4P79 A;  5BRM A;  4Q0T A;  1SIR A;  5K3G A;  4NXL A;  3MMO A;  3BNH A;  3C2P A;  3AFF A;  2OT4 A;  2R05 A;  1K93 A;  4H7Q A;  4AI6 A;  4H85 A;  3RKH A;  1IVH A;  4JIO A;  4L3Y A;  5B5W A;  1UKW A;  2FP1 A;  4LQQ B;  4E01 A;  4J1V A;  1U8V A;  1IS2 A;  2PO4 A;  4X28 A;  2AZE A;  4DZY A;  3M9V A;  3FO3 A;  5M4M A;  4LQS B;  3C3L A;  4AKI A;  5K3H A;  4KSA A;  3TOR A;  4E00 A;  3C46 A;  3NF4 A;  1GJV A;  4MPE A;  3TZ0 A;  2Z1Q A;  4X28 C;  2A1T A;  1RP3 A;  4FF4 A;  3CE2 A;  4N5F A;  1SK6 A;  3MPI A;  2BU8 A;  1K8T A;  1R3B A;  3F29 A;  2Q8I A;  4M9A A;  1XFX A;  1LVC A;  3SXQ A;  3X29 A;  3VKG A;  2RDZ A;  2CJ7 A;  2YGW A;  1Y8N A;  2EBA A;  4DOY A;  3D9G A;  3AFE A;  4W9U A;  1XG2 B;  4G5E A;  3Q23 A;  5EZ3 A;  3X0X A;  4P13 A;  1RJ4 A;  3OWM A;  1UDY A;  2YYJ A;  2EBF X;  2R03 A;  1XFV A;  3SCE A;  4KS9 A;  3R7K A;  3Q24 A;  2YYM A;  4V26 A; 
#chains in the Genus database with same CATH homology
 3FCJ A;  4ZXV A;  2C0U A;  3PFD A;  1RX0 A;  3EON A;  4HR3 A;  1WS9 A;  2ZAF A;  3SF6 A;  1FS9 A;  4L3Z A;  2REH A;  3D9D A;  4KTO A;  4JEK A;  2E80 A;  3D9F A;  3TTB A;  2JBS A;  3S7W A;  1BUC A;  3UBR A;  4Q5C A;  3X0Y A;  3LG1 A;  2IX5 A;  2C12 A;  2FON A;  2D29 A;  2R0M A;  4KCF A;  3L1T A;  1QDB A;  2E81 A;  2OR0 A;  4Q5B A;  2YYK A;  3GQT A;  3MKH A;  4RM7 A;  3II9 A;  3BNG A;  3MPJ A;  1EGD A;  4L38 A;  2RFQ A;  3MDE A;  3UU9 A;  4XVX A;  3BNJ A;  2YYI A;  1R2J A;  4O5M A;  3GNC A;  3HWC A;  2WBI A;  1FS7 A;  5K3J A;  3EOM A;  2R0N A;  1EGC A;  3OWA A;  4IV6 A;  2DDH A;  4U83 A;  4Q1O A;  2J7A A;  3GM6 A;  1EGE A;  2VR0 A;  3OIB A;  3P4T A;  3BNF A;  4Q4U A;  3MXL A;  1SIQ A;  4L1F A;  1GU6 A;  2JIF A;  2ZO5 A;  4Q17 A;  2DVL A;  1FS8 A;  3SWO A;  4WJY A;  4OO2 A;  3MDD A;  5K3I A;  3LGQ A;  2RF7 A;  2PG0 A;  3D9E A;  1OAH A;  1T9G A;  2JBR A;  4L3X A;  4IRN A;  3B96 A;  1JQI A;  2YYL A;  2UXW A;  3D6B A;  3D1I A;  2IX6 A;  4ZYJ A;  2CX9 A;  2JBT A;  2YYG A;  2VIG A;  1W07 A;  4Q0T A;  1SIR A;  5K3G A;  4NXL A;  3MMO A;  3BNH A;  3AFF A;  2OT4 A;  3RKH A;  1IVH A;  4L3Y A;  1UKW A;  1U8V A;  1IS2 A;  4X28 A;  3M9V A;  3FO3 A;  5K3H A;  3TOR A;  3NF4 A;  2Z1Q A;  4X28 C;  2A1T A;  4N5F A;  3MPI A;  3F29 A;  4M9A A;  3SXQ A;  2RDZ A;  4G5E A;  2EBA A;  4DOY A;  3D9G A;  3AFE A;  4W9U A;  3X0X A;  4P13 A;  3OWM A;  1UDY A;  2YYJ A;  3SCE A;  3R7K A;  2YYM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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