4HR3A

Structure of a putative acyl-coa dehydrogenase from mycobacterium abscessus
Total Genus 145
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
145
sequence length
407
structure length
407
Chain Sequence
FAPSARAAELIAAVREFIDAEVMPVERAVLAHHDELLGARAGTTAELWHVPPELDSLKAKARAAGLWNLFLPDPELGGGLSNSEYAPLAEQMGRSLFAPTVFNCNAPDSGNMEVLHRYGSQEQKEVWLEPLLEGDIRSAFCMTEPDVASSDATNMAATAVVEGDEVVINGRKWWSTGVGHPDCKVIIFMGLTDPNAHRYARHSMVLVPMDTPGITVERMLPTMGFYDEPGGHGVVSFDNVRLPADAFIAGPGKGFEIAQGRLGPGRVHHAMRLIGLAEVALEHACRRGLDRTAFGKPLVNLGGNRERIADARIAINQTRLLVLHAAWLLDTVGIMGALSAVSEIKVAAPNMAQQVIDMAIQIHGGGGLSNDFPLAAAWVNARALRLADGPDEVHRGVVARIELAKYA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Oxidoreductase
molecule keywords Putative acyl-CoA dehydrogenase
publication title Increasing the structural coverage of tuberculosis drug targets.
pubmed doi rcsb
source organism Mycobacterium abscessus
total genus 145
structure length 407
sequence length 407
ec nomenclature
pdb deposition date 2012-10-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 4hr3A01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 4hr3A03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 4hr3A02
4L3YA 3OIBA 3SCEA 2C12A 3PFDA 3TTBA 2E80A 1UDYA 4X28A 2IX6A 4N5FA 3D9GA 1FS9A 3EONA 2OR0A 3LGQA 3L1TA 2OT4A 2YYIA 2A1TA 4Q5CA 1GU6A 4Q0TA 2WBIA 2YYJA 4KCFA 3II9A 3X0XA 3M9VA 2RFQA 2CX9A 3MKHA 5K3JA 3SWOA 2C0UA 4ZYJA 2J7AA 3MDEA 3RKHA 4Q1OA 2YYKA 3MPIA 1FS7A 1SIRA 4NXLA 1OAHA 3D6BA 3FCJA 2E81A 1WS9A 4ZXVA 3GNCA 4DOYA 1T9GA 2FONA 3AFFA 3BNHA 1W07A 4P13A 3D1IA 3F29A 2IX5A 2PG0A 2JIFA 3BNGA 2JBSA 2D29A 2JBTA 2JBRA 3FO3A 3NF4A 2Z1QA 4L3XA 4G5EA 3D9EA 2YYLA 2RF7A 2YYMA 5K3HA 3OWAA 3EOMA 4RM7A 3MMOA 4OO2A 4U83A 3HWCA 3SXQA 3D9FA 2RDZA 3OWMA 3X0YA 4Q5BA 3S7WA 3D9DA 3BNJA 3UU9A 4IRNA 4Q17A 2VR0A 2ZO5A 4M9AA 1U8VA 5K3GA 1R2JA 1JQIA 4JEKA 1BUCA 2YYGA 1IS2A 1EGEA 3R7KA 4L38A 2EBAA 3P4TA 1EGCA 1UKWA 3MDDA 4IV6A 4O5MA 2R0NA 4L3ZA 4XVXA 3MXLA 1RX0A 2REHA 4L1FA 3TORA 2DVLA 1QDBA 2DDHA 4HR3A 4W9UA 2R0MA 2UXWA 4X28C 3AFEA 3UBRA 3BNFA 3LG1A 1FS8A 3GQTA 3MPJA 1EGDA 3B96A 2ZAFA 1IVHA 3GM6A 4Q4UA 1SIQA 2VIGA 3SF6A 4WJYA 5K3IA 4KTOA
chains in the Genus database with same CATH superfamily
2HJNA 4L3YA 3VADA 3OIBA 1Y8OA 3SCEA 3C3LA 4J1VA 2XQRB 2C12A 2FP1A 3D2RA 1PK0A 1Y8PA 3PFDA 1X90A 2BU8A 1Y8NA 2CJ4A 2E80A 2ZDXA 4JIZA 4JIOA 1UDYA 4MP2A 4MPCA 2Q8HA 5BRKA 5J6AA 4X28A 5M4NA 5GJWE 1GKZA 2IX6A 4LQQB 3U33A 5B6BA 4N5FA 2CJ6A 3D9GA 1FS9A 3N0RA 4KS9A 3EONA 1XFXA 5M4PA 2OR0A 2F6LA 2OJQA 2YGWA 3L1TA 3LGQA 4V25A 2OT4A 2YYIA 2R03A 3TZ5A 4H81A 2A1TA 4Q5CA 1GU6A 4Q0TA 2WBIA 2CJ5A 2YYJA 4KCFA 3II9A 2EBFX 3X0XA 3M9VA 2RFQA 2CX9A 3MKHA 5K3JA 3SWOA 1SK6A 2C0UA 2R05A 4ZYJA 1K90A 2J7AA 3MDEA 4AKGA 3RKHA 1Y0VA 3TZ2A 5J71A 4FF4A 4Q1OA 2YYKA 3MPIA 2E0AA 1FS7A 1SIRA 4NXLA 1OAHA 3D6BA 1X8ZA 3FCJA 4MP7A 2E81A 1WS9A 2BTZA 4ZXVA 2AO2A 3GNCA 2CJ7A 4HKRA 4F0XA 5B5WA 4DOYA 1XFVA 1T9GA 4AI6A 1XFWA 3DJLA 2ZDYA 2FONA 2CJ8A 3AFFA 3BNHA 1GKXA 1W07A 2Q8IA 4P13A 2EBHX 2OEVA 2BU5A 3D1IA 3F29A 3TZ4A 3CE2A 1XFUA 2IX5A 5B5VA 2PG0A 1R3BA 1XFYA 2JIFA 2XS8A 3BNGA 2JBSA 3X29A 2D29A 2JBTA 2JBRA 3FO3A 4MPNA 4P79A 3Q22A 3NF4A 2Z1QA 4L3XA 4G5EA 5M4KA 3D9EA 1RJ1A 2YYLA 2RF7A 4H7QA 2R02A 3VKGA 2YYMA 2PNRA 5K3HA 3OWAA 3EOMA 3TZ0A 4RM7A 3MMOA 4OO2A 4U83A 3HWCA 3CRKA 3SXQA 4AKIA 3D9FA 2GBBA 2RDZA 3C46A 3OWMA 3X0YA 2BU6A 2FP2A 2XS1A 4Q5BA 3D9DA 3S7WA 3BNJA 3UU9A 2BU2A 3Q23A 4IRNA 4Q17A 4AKHA 3KMLA 2VR0A 4H85A 2ZO5A 2QR4A 4M9AA 1U8VA 1XFZA 4E00A 3C2PA 4KSAA 5BRMA 5K3GA 1R2JA 2BU7A 1JQIA 1S26A 4JEKA 4E02A 1BUCA 4E01A 2AZEA 2YYGA 1JM6A 3CRLA 1IS2A 1EGEA 3R7KA 1LVCA 2EBAA 4G97A 1K8TA 4L38A 4DZYA 3P4TA 4FF2A 1EGCA 4QICA 1UKWA 4V26A 3MDDA 4IV6A 2EC5A 4HKSA 2ZKJA 5GJVE 4O5MA 2Q8FA 1K93A 4KSFA 2R0NA 3Q24A 4L3ZA 4XVXA 2LFWA 3MXLA 1RX0A 2REHA 4L1FA 4LQSB 4MPEA 2DVLA 1SC5A 3TORA 3TTBA 1QDBA 2DDHA 4FF3A 1XG2B 4HR3A 5M4MA 4W9UA 2R0MA 4FF1A 2UXWA 4X28C 3AFEA 1PI1A 3UBRA 3BNFA 3LG1A 1FS8A 2OEXA 3GQTA 3MPJA 1GJVA 1RP3A 1RJ4A 3Q0AA 5EZ3A 2Q8GA 1EGDA 3B96A 3VKHA 2ZAFA 1IVHA 2VF1A 3GM6A 1SIQA 2VIGA 3SF6A 4FZ4A 4Q4UA 4WJYA 1X91A 5K3IA 4KTOA 2PO4A
chains in the Genus database with same CATH topology
4L3YA 3OIBA 3SCEA 2C12A 3PFDA 3TTBA 2E80A 1UDYA 4X28A 2IX6A 4N5FA 3D9GA 1FS9A 3EONA 2OR0A 3LGQA 3L1TA 2OT4A 2YYIA 2A1TA 4Q5CA 1GU6A 4Q0TA 2WBIA 2YYJA 4KCFA 3II9A 3X0XA 3M9VA 2RFQA 2CX9A 3MKHA 5K3JA 3SWOA 2C0UA 4ZYJA 2J7AA 3MDEA 3RKHA 4Q1OA 2YYKA 3MPIA 1FS7A 1SIRA 4NXLA 1OAHA 3D6BA 3FCJA 2E81A 1WS9A 4ZXVA 3GNCA 4DOYA 1T9GA 2FONA 3AFFA 3BNHA 1W07A 4P13A 3D1IA 3F29A 2IX5A 2PG0A 2JIFA 3BNGA 2JBSA 2D29A 2JBTA 2JBRA 3FO3A 3NF4A 2Z1QA 4L3XA 4G5EA 3D9EA 2YYLA 2RF7A 2YYMA 5K3HA 3OWAA 3EOMA 4RM7A 3MMOA 4OO2A 4U83A 3HWCA 3SXQA 3D9FA 2RDZA 3OWMA 3X0YA 4Q5BA 3S7WA 3D9DA 3BNJA 3UU9A 4IRNA 4Q17A 2VR0A 2ZO5A 4M9AA 1U8VA 5K3GA 1R2JA 1JQIA 4JEKA 1BUCA 2YYGA 1IS2A 1EGEA 3R7KA 4L38A 2EBAA 3P4TA 1EGCA 1UKWA 3MDDA 4IV6A 4O5MA 2R0NA 4L3ZA 4XVXA 3MXLA 1RX0A 2REHA 4L1FA 3TORA 2DVLA 1QDBA 2DDHA 4HR3A 4W9UA 2R0MA 2UXWA 4X28C 3AFEA 3UBRA 3BNFA 3LG1A 1FS8A 3GQTA 3MPJA 1EGDA 3B96A 2ZAFA 1IVHA 3GM6A 4Q4UA 1SIQA 2VIGA 3SF6A 4WJYA 5K3IA 4KTOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L3Y A;  3OIB A;  3SCE A;  2C12 A;  3PFD A;  3TTB A;  2E80 A;  1UDY A;  4X28 A;  2IX6 A;  4N5F A;  3D9G A;  1FS9 A;  3EON A;  2OR0 A;  3LGQ A;  3L1T A;  2OT4 A;  2YYI A;  2A1T A;  4Q5C A;  1GU6 A;  4Q0T A;  2WBI A;  2YYJ A;  4KCF A;  3II9 A;  3X0X A;  3M9V A;  2RFQ A;  2CX9 A;  3MKH A;  5K3J A;  3SWO A;  2C0U A;  4ZYJ A;  2J7A A;  3MDE A;  3RKH A;  4Q1O A;  2YYK A;  3MPI A;  1FS7 A;  1SIR A;  4NXL A;  1OAH A;  3D6B A;  3FCJ A;  2E81 A;  1WS9 A;  4ZXV A;  3GNC A;  4DOY A;  1T9G A;  2FON A;  3AFF A;  3BNH A;  1W07 A;  4P13 A;  3D1I A;  3F29 A;  2IX5 A;  2PG0 A;  2JIF A;  3BNG A;  2JBS A;  2D29 A;  2JBT A;  2JBR A;  3FO3 A;  3NF4 A;  2Z1Q A;  4L3X A;  4G5E A;  3D9E A;  2YYL A;  2RF7 A;  2YYM A;  5K3H A;  3OWA A;  3EOM A;  4RM7 A;  3MMO A;  4OO2 A;  4U83 A;  3HWC A;  3SXQ A;  3D9F A;  2RDZ A;  3OWM A;  3X0Y A;  4Q5B A;  3S7W A;  3D9D A;  3BNJ A;  3UU9 A;  4IRN A;  4Q17 A;  2VR0 A;  2ZO5 A;  4M9A A;  1U8V A;  5K3G A;  1R2J A;  1JQI A;  4JEK A;  1BUC A;  2YYG A;  1IS2 A;  1EGE A;  3R7K A;  4L38 A;  2EBA A;  3P4T A;  1EGC A;  1UKW A;  3MDD A;  4IV6 A;  4O5M A;  2R0N A;  4L3Z A;  4XVX A;  3MXL A;  1RX0 A;  2REH A;  4L1F A;  3TOR A;  2DVL A;  1QDB A;  2DDH A;  4HR3 A;  4W9U A;  2R0M A;  2UXW A;  4X28 C;  3AFE A;  3UBR A;  3BNF A;  3LG1 A;  1FS8 A;  3GQT A;  3MPJ A;  1EGD A;  3B96 A;  2ZAF A;  1IVH A;  3GM6 A;  4Q4U A;  1SIQ A;  2VIG A;  3SF6 A;  4WJY A;  5K3I A;  4KTO A; 
#chains in the Genus database with same CATH topology
 2HJN A;  4L3Y A;  3VAD A;  3OIB A;  1Y8O A;  3SCE A;  3C3L A;  4J1V A;  2XQR B;  2C12 A;  2FP1 A;  3D2R A;  1PK0 A;  1Y8P A;  3PFD A;  1X90 A;  2BU8 A;  1Y8N A;  2CJ4 A;  2E80 A;  2ZDX A;  4JIZ A;  4JIO A;  1UDY A;  4MP2 A;  4MPC A;  2Q8H A;  5BRK A;  5J6A A;  4X28 A;  5M4N A;  5GJW E;  1GKZ A;  2IX6 A;  4LQQ B;  3U33 A;  5B6B A;  4N5F A;  2CJ6 A;  3D9G A;  1FS9 A;  3N0R A;  4KS9 A;  3EON A;  1XFX A;  5M4P A;  2OR0 A;  2F6L A;  2OJQ A;  2YGW A;  3L1T A;  3LGQ A;  4V25 A;  2OT4 A;  2YYI A;  2R03 A;  3TZ5 A;  4H81 A;  2A1T A;  4Q5C A;  1GU6 A;  4Q0T A;  2WBI A;  2CJ5 A;  2YYJ A;  4KCF A;  3II9 A;  2EBF X;  3X0X A;  3M9V A;  2RFQ A;  2CX9 A;  3MKH A;  5K3J A;  3SWO A;  1SK6 A;  2C0U A;  2R05 A;  4ZYJ A;  1K90 A;  2J7A A;  3MDE A;  4AKG A;  3RKH A;  1Y0V A;  3TZ2 A;  5J71 A;  4FF4 A;  4Q1O A;  2YYK A;  3MPI A;  2E0A A;  1FS7 A;  1SIR A;  4NXL A;  1OAH A;  3D6B A;  1X8Z A;  3FCJ A;  4MP7 A;  2E81 A;  1WS9 A;  2BTZ A;  4ZXV A;  2AO2 A;  3GNC A;  2CJ7 A;  4HKR A;  4F0X A;  5B5W A;  4DOY A;  1XFV A;  1T9G A;  4AI6 A;  1XFW A;  3DJL A;  2ZDY A;  2FON A;  2CJ8 A;  3AFF A;  3BNH A;  1GKX A;  1W07 A;  2Q8I A;  4P13 A;  2EBH X;  2OEV A;  2BU5 A;  3D1I A;  3F29 A;  3TZ4 A;  3CE2 A;  1XFU A;  2IX5 A;  5B5V A;  2PG0 A;  1R3B A;  1XFY A;  2JIF A;  2XS8 A;  3BNG A;  2JBS A;  3X29 A;  2D29 A;  2JBT A;  2JBR A;  3FO3 A;  4MPN A;  4P79 A;  3Q22 A;  3NF4 A;  2Z1Q A;  4L3X A;  4G5E A;  5M4K A;  3D9E A;  1RJ1 A;  2YYL A;  2RF7 A;  4H7Q A;  2R02 A;  3VKG A;  2YYM A;  2PNR A;  5K3H A;  3OWA A;  3EOM A;  3TZ0 A;  4RM7 A;  3MMO A;  4OO2 A;  4U83 A;  3HWC A;  3CRK A;  3SXQ A;  4AKI A;  3D9F A;  2GBB A;  2RDZ A;  3C46 A;  3OWM A;  3X0Y A;  2BU6 A;  2FP2 A;  2XS1 A;  4Q5B A;  3D9D A;  3S7W A;  3BNJ A;  3UU9 A;  2BU2 A;  3Q23 A;  4IRN A;  4Q17 A;  4AKH A;  3KML A;  2VR0 A;  4H85 A;  2ZO5 A;  2QR4 A;  4M9A A;  1U8V A;  1XFZ A;  4E00 A;  3C2P A;  4KSA A;  5BRM A;  5K3G A;  1R2J A;  2BU7 A;  1JQI A;  1S26 A;  4JEK A;  4E02 A;  1BUC A;  4E01 A;  2AZE A;  2YYG A;  1JM6 A;  3CRL A;  1IS2 A;  1EGE A;  3R7K A;  1LVC A;  2EBA A;  4G97 A;  1K8T A;  4L38 A;  4DZY A;  3P4T A;  4FF2 A;  1EGC A;  4QIC A;  1UKW A;  4V26 A;  3MDD A;  4IV6 A;  2EC5 A;  4HKS A;  2ZKJ A;  5GJV E;  4O5M A;  2Q8F A;  1K93 A;  4KSF A;  2R0N A;  3Q24 A;  4L3Z A;  4XVX A;  2LFW A;  3MXL A;  1RX0 A;  2REH A;  4L1F A;  4LQS B;  4MPE A;  2DVL A;  1SC5 A;  3TOR A;  3TTB A;  1QDB A;  2DDH A;  4FF3 A;  1XG2 B;  4HR3 A;  5M4M A;  4W9U A;  2R0M A;  4FF1 A;  2UXW A;  4X28 C;  3AFE A;  1PI1 A;  3UBR A;  3BNF A;  3LG1 A;  1FS8 A;  2OEX A;  3GQT A;  3MPJ A;  1GJV A;  1RP3 A;  1RJ4 A;  3Q0A A;  5EZ3 A;  2Q8G A;  1EGD A;  3B96 A;  3VKH A;  2ZAF A;  1IVH A;  2VF1 A;  3GM6 A;  1SIQ A;  2VIG A;  3SF6 A;  4FZ4 A;  4Q4U A;  4WJY A;  1X91 A;  5K3I A;  4KTO A;  2PO4 A; 
#chains in the Genus database with same CATH homology
 4L3Y A;  3OIB A;  3SCE A;  2C12 A;  3PFD A;  3TTB A;  2E80 A;  1UDY A;  4X28 A;  2IX6 A;  4N5F A;  3D9G A;  1FS9 A;  3EON A;  2OR0 A;  3LGQ A;  3L1T A;  2OT4 A;  2YYI A;  2A1T A;  4Q5C A;  1GU6 A;  4Q0T A;  2WBI A;  2YYJ A;  4KCF A;  3II9 A;  3X0X A;  3M9V A;  2RFQ A;  2CX9 A;  3MKH A;  5K3J A;  3SWO A;  2C0U A;  4ZYJ A;  2J7A A;  3MDE A;  3RKH A;  4Q1O A;  2YYK A;  3MPI A;  1FS7 A;  1SIR A;  4NXL A;  1OAH A;  3D6B A;  3FCJ A;  2E81 A;  1WS9 A;  4ZXV A;  3GNC A;  4DOY A;  1T9G A;  2FON A;  3AFF A;  3BNH A;  1W07 A;  4P13 A;  3D1I A;  3F29 A;  2IX5 A;  2PG0 A;  2JIF A;  3BNG A;  2JBS A;  2D29 A;  2JBT A;  2JBR A;  3FO3 A;  3NF4 A;  2Z1Q A;  4L3X A;  4G5E A;  3D9E A;  2YYL A;  2RF7 A;  2YYM A;  5K3H A;  3OWA A;  3EOM A;  4RM7 A;  3MMO A;  4OO2 A;  4U83 A;  3HWC A;  3SXQ A;  3D9F A;  2RDZ A;  3OWM A;  3X0Y A;  4Q5B A;  3S7W A;  3D9D A;  3BNJ A;  3UU9 A;  4IRN A;  4Q17 A;  2VR0 A;  2ZO5 A;  4M9A A;  1U8V A;  5K3G A;  1R2J A;  1JQI A;  4JEK A;  1BUC A;  2YYG A;  1IS2 A;  1EGE A;  3R7K A;  4L38 A;  2EBA A;  3P4T A;  1EGC A;  1UKW A;  3MDD A;  4IV6 A;  4O5M A;  2R0N A;  4L3Z A;  4XVX A;  3MXL A;  1RX0 A;  2REH A;  4L1F A;  3TOR A;  2DVL A;  1QDB A;  2DDH A;  4HR3 A;  4W9U A;  2R0M A;  2UXW A;  4X28 C;  3AFE A;  3UBR A;  3BNF A;  3LG1 A;  1FS8 A;  3GQT A;  3MPJ A;  1EGD A;  3B96 A;  2ZAF A;  1IVH A;  3GM6 A;  4Q4U A;  1SIQ A;  2VIG A;  3SF6 A;  4WJY A;  5K3I A;  4KTO A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...