4OO2A

Streptomyces globisporus c-1027 fad dependent (s)-3-chloro-β-tyrosine-s-sgcc2 c-5 hydroxylase sgcc apo form
Total Genus 170
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
170
sequence length
510
structure length
506
Chain Sequence
TRPLTGEEYLESLRDAREVYLDGSRVKDVTAHPAFHNPARMTARLYDSLHDPAQKAVLTAPTDAGDGFTHRFFTAPRSVDDLVKDQAAIASWARKSYGWMGRSPDYKASFLGTLGANADFYEPFADNARRWYRESQEKVLYWNHAFLHPPVDRSEVGDVFIHVERETDAGLVVSGAKVVATGSALTHAAFISHWGLPIKDRKFALVATVPMDADGLKVICRPSYSANAATTGSPFDNPLSSRLDENDAILVLDQVLIPWENVFVYGNLGKVHLLAGQSGMIERATFHGCTRLAVKLEFIAGLLAKALDITGAKDFRGVQTRLGEVLAWRNLFWSLSDAAARNPVPWKNGTLLPNPQAGMAYRWFMQIGYPRVLEIVQQDVASGLMYVNSSTEDFRNPETGPYLEKYLRGSDGAGAVERVKVMKLLWDAVGSDFGGRHELYERNYSGNHENTRIELLLSQTASGKLDSYMDFAQACMDEYDLDGWTAPDLESFHAMRSASRDLLGGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Chlorophenol-4-monooxygenase
publication title Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus.
pubmed doi rcsb
source organism Streptomyces globisporus
molecule tags Oxidoreductase
total genus 170
structure length 506
sequence length 510
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2014-01-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03241 HpaB 4-hydroxyphenylacetate 3-hydroxylase C terminal
A PF11794 HpaB_N 4-hydroxyphenylacetate 3-hydroxylase N terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 4oo2A02
3GQTA 1SIQA 3FO3A 3P4TA 4WJYA 3MMOA 2IX6A 3MXLA 3X0YA 2E81A 3RKHA 1RX0A 2C12A 4NXLA 4P13A 5K3IA 4L1FA 3GM6A 3TTBA 3MPJA 4ZXVA 3AFEA 2ZO5A 3FCJA 1JQIA 2VR0A 3EOMA 3BNGA 1OAHA 1QDBA 2R0MA 2JBTA 3SCEA 4L3XA 1GU6A 2FONA 2PG0A 2YYJA 2YYKA 4L3ZA 4Q5BA 2OT4A 2Z1QA 3UBRA 3EONA 1T9GA 1UDYA 3R7KA 3GNCA 3MDEA 3F29A 4Q17A 1UKWA 4JEKA 5K3GA 4DOYA 3UU9A 2IX5A 2JBRA 2RFQA 2REHA 5K3JA 2YYLA 2JBSA 3MPIA 4KTOA 1U8VA 2EBAA 2RF7A 1R2JA 3TORA 4X28C 3MDDA 3D1IA 1EGDA 1FS8A 3SF6A 2JIFA 4Q1OA 4O5MA 2D29A 3D6BA 5K3HA 1BUCA 3D9GA 2UXWA 3SWOA 3D9FA 3D9EA 3M9VA 3X0XA 4IRNA 4L38A 2YYIA 3OIBA 2RDZA 3S7WA 2A1TA 1EGEA 3AFFA 1IS2A 3PFDA 4N5FA 3L1TA 2OR0A 3BNHA 2YYMA 3II9A 3LGQA 2ZAFA 1FS7A 3OWAA 2R0NA 4XVXA 2DDHA 2YYGA 2WBIA 3LG1A 4G5EA 3MKHA 4W9UA 4X28A 3SXQA 1EGCA 2E80A 4IV6A 2DVLA 4HR3A 3BNFA 1IVHA 2CX9A 4M9AA 2C0UA 3D9DA 4L3YA 1WS9A 3OWMA 4OO2A 1SIRA 2J7AA 4Q4UA 1FS9A 3NF4A 3B96A 4Q0TA 4RM7A 1W07A 3BNJA 2VIGA 4ZYJA 3HWCA 4KCFA 4U83A 4Q5CA
chains in the Genus database with same CATH superfamily
3GQTA 1SIQA 4KS9A 3FO3A 3P4TA 4WJYA 1K90A 2IX6A 3MMOA 3MXLA 3X0YA 4FF4A 2R03A 2E81A 1XFYA 1SK6A 3X29A 3RKHA 1RX0A 2C12A 4NXLA 4P13A 5K3IA 1K93A 2XS1A 1GJVA 2R05A 2CJ4A 3GM6A 4L1FA 3CRKA 3TTBA 1X8ZA 3MPJA 4ZXVA 3AFEA 3D2RA 1Y8OA 2EBFX 2ZO5A 3FCJA 5M4MA 2F6LA 1JQIA 2OEXA 2VR0A 1JM6A 3EOMA 2Q8GA 3BNGA 1OAHA 1QDBA 2R0MA 1S26A 1K8TA 1XFVA 2JBTA 4G97A 4QICA 4V25A 3TZ2A 3VKGA 1XG2B 3SCEA 2VF1A 4L3XA 1RP3A 2BU8A 1GU6A 3C2PA 2CJ5A 2FONA 2PG0A 3CE2A 2YYJA 2YYKA 4L3ZA 1Y8NA 5B5VA 4Q5BA 5BRMA 3TZ5A 3C46A 2OT4A 2GBBA 1PK0A 2Z1QA 2BU7A 3UBRA 3Q23A 3EONA 3TZ0A 1GKZA 1T9GA 4KSFA 1RJ4A 1UDYA 3R7KA 3GNCA 2BU2A 3MDEA 3CRLA 2CJ8A 1UKWA 2LFWA 3F29A 4H7QA 4JEKA 4Q17A 5GJWE 4DOYA 2BU5A 5K3GA 4LQQB 1Y0VA 4DZYA 3UU9A 2IX5A 2JBRA 4P79A 1PI1A 2FP2A 2RFQA 2REHA 5K3JA 2YYLA 3N0RA 2JBSA 3MPIA 1XFXA 4KTOA 2Q8FA 4E00A 1U8VA 2EBAA 3TZ4A 2RF7A 2FP1A 4E02A 1R2JA 2Q8IA 1R3BA 4X28C 1XFZA 2CJ6A 3TORA 4KSAA 3MDDA 4HKSA 3D1IA 1EGDA 1FS8A 4JIOA 3SF6A 4FZ4A 2JIFA 4AKHA 2EBHX 4FF2A 4Q1OA 1X90A 2ZDXA 4O5MA 2D29A 3D6BA 4E01A 4J1VA 5K3HA 1BUCA 3D9GA 2UXWA 3SWOA 3D9FA 2OJQA 4MP2A 4H85A 3D9EA 3M9VA 3C3LA 3Q22A 2R02A 3X0XA 3VKHA 4IRNA 1XFWA 2AO2A 2YYIA 4L38A 5M4KA 3OIBA 2RDZA 4MPEA 4F0XA 1LVCA 2A1TA 1EGEA 3AFFA 3S7WA 1IS2A 4MPCA 3PFDA 4H81A 4HKRA 4N5FA 3L1TA 2OR0A 3BNHA 2YYMA 3II9A 3KMLA 4JIZA 3LGQA 2PO4A 2ZAFA 5J71A 4FF3A 1XFUA 1FS7A 4AKIA 4AKGA 3OWAA 2E0AA 2R0NA 2BTZA 2ZKJA 4XVXA 2DDHA 2YYGA 2WBIA 3LG1A 4G5EA 3MKHA 4W9UA 1RJ1A 4X28A 3SXQA 5M4NA 1EGCA 3Q24A 2E80A 5J6AA 4IV6A 2AZEA 2DVLA 2QR4A 4HR3A 5BRKA 1SC5A 3Q0AA 4FF1A 3BNFA 3VADA 4LQSB 5B6BA 2CJ7A 2HJNA 5GJVE 1IVHA 2CX9A 2PNRA 4M9AA 2C0UA 3D9DA 4AI6A 4L3YA 1Y8PA 1WS9A 4MP7A 3OWMA 1GKXA 4MPNA 4OO2A 1SIRA 5M4PA 2J7AA 2Q8HA 4Q4UA 1FS9A 4V26A 3NF4A 2OEVA 2XS8A 3B96A 2EC5A 4Q0TA 4RM7A 5B5WA 1W07A 1X91A 2BU6A 2XQRB 2ZDYA 2VIGA 3BNJA 3HWCA 4KCFA 4ZYJA 2YGWA 4U83A 4Q5CA
chains in the Genus database with same CATH topology
3GQTA 1SIQA 3FO3A 3P4TA 4WJYA 3MMOA 2IX6A 3MXLA 3X0YA 2E81A 3RKHA 1RX0A 2C12A 4NXLA 4P13A 5K3IA 4L1FA 3GM6A 3TTBA 3MPJA 4ZXVA 3AFEA 2ZO5A 3FCJA 1JQIA 2VR0A 3EOMA 3BNGA 1OAHA 1QDBA 2R0MA 2JBTA 3SCEA 4L3XA 1GU6A 2FONA 2PG0A 2YYJA 2YYKA 4L3ZA 4Q5BA 2OT4A 2Z1QA 3UBRA 3EONA 1T9GA 1UDYA 3R7KA 3GNCA 3MDEA 3F29A 4Q17A 1UKWA 4JEKA 5K3GA 4DOYA 3UU9A 2IX5A 2JBRA 2RFQA 2REHA 5K3JA 2YYLA 2JBSA 3MPIA 4KTOA 1U8VA 2EBAA 2RF7A 1R2JA 3TORA 4X28C 3MDDA 3D1IA 1EGDA 1FS8A 3SF6A 2JIFA 4Q1OA 4O5MA 2D29A 3D6BA 5K3HA 1BUCA 3D9GA 2UXWA 3SWOA 3D9FA 3D9EA 3M9VA 3X0XA 4IRNA 4L38A 2YYIA 3OIBA 2RDZA 3S7WA 2A1TA 1EGEA 3AFFA 1IS2A 3PFDA 4N5FA 3L1TA 2OR0A 3BNHA 2YYMA 3II9A 3LGQA 2ZAFA 1FS7A 3OWAA 2R0NA 4XVXA 2DDHA 2YYGA 2WBIA 3LG1A 4G5EA 3MKHA 4W9UA 4X28A 3SXQA 1EGCA 2E80A 4IV6A 2DVLA 4HR3A 3BNFA 1IVHA 2CX9A 4M9AA 2C0UA 3D9DA 4L3YA 1WS9A 3OWMA 4OO2A 1SIRA 2J7AA 4Q4UA 1FS9A 3NF4A 3B96A 4Q0TA 4RM7A 1W07A 3BNJA 2VIGA 4ZYJA 3HWCA 4KCFA 4U83A 4Q5CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GQT A;  1SIQ A;  3FO3 A;  3P4T A;  4WJY A;  3MMO A;  2IX6 A;  3MXL A;  3X0Y A;  2E81 A;  3RKH A;  1RX0 A;  2C12 A;  4NXL A;  4P13 A;  5K3I A;  4L1F A;  3GM6 A;  3TTB A;  3MPJ A;  4ZXV A;  3AFE A;  2ZO5 A;  3FCJ A;  1JQI A;  2VR0 A;  3EOM A;  3BNG A;  1OAH A;  1QDB A;  2R0M A;  2JBT A;  3SCE A;  4L3X A;  1GU6 A;  2FON A;  2PG0 A;  2YYJ A;  2YYK A;  4L3Z A;  4Q5B A;  2OT4 A;  2Z1Q A;  3UBR A;  3EON A;  1T9G A;  1UDY A;  3R7K A;  3GNC A;  3MDE A;  3F29 A;  4Q17 A;  1UKW A;  4JEK A;  5K3G A;  4DOY A;  3UU9 A;  2IX5 A;  2JBR A;  2RFQ A;  2REH A;  5K3J A;  2YYL A;  2JBS A;  3MPI A;  4KTO A;  1U8V A;  2EBA A;  2RF7 A;  1R2J A;  3TOR A;  4X28 C;  3MDD A;  3D1I A;  1EGD A;  1FS8 A;  3SF6 A;  2JIF A;  4Q1O A;  4O5M A;  2D29 A;  3D6B A;  5K3H A;  1BUC A;  3D9G A;  2UXW A;  3SWO A;  3D9F A;  3D9E A;  3M9V A;  3X0X A;  4IRN A;  4L38 A;  2YYI A;  3OIB A;  2RDZ A;  3S7W A;  2A1T A;  1EGE A;  3AFF A;  1IS2 A;  3PFD A;  4N5F A;  3L1T A;  2OR0 A;  3BNH A;  2YYM A;  3II9 A;  3LGQ A;  2ZAF A;  1FS7 A;  3OWA A;  2R0N A;  4XVX A;  2DDH A;  2YYG A;  2WBI A;  3LG1 A;  4G5E A;  3MKH A;  4W9U A;  4X28 A;  3SXQ A;  1EGC A;  2E80 A;  4IV6 A;  2DVL A;  4HR3 A;  3BNF A;  1IVH A;  2CX9 A;  4M9A A;  2C0U A;  3D9D A;  4L3Y A;  1WS9 A;  3OWM A;  4OO2 A;  1SIR A;  2J7A A;  4Q4U A;  1FS9 A;  3NF4 A;  3B96 A;  4Q0T A;  4RM7 A;  1W07 A;  3BNJ A;  2VIG A;  4ZYJ A;  3HWC A;  4KCF A;  4U83 A;  4Q5C A; 
#chains in the Genus database with same CATH topology
 3GQT A;  1SIQ A;  4KS9 A;  3FO3 A;  3P4T A;  4WJY A;  1K90 A;  2IX6 A;  3MMO A;  3MXL A;  3X0Y A;  4FF4 A;  2R03 A;  2E81 A;  1XFY A;  1SK6 A;  3X29 A;  3RKH A;  1RX0 A;  2C12 A;  4NXL A;  4P13 A;  5K3I A;  1K93 A;  2XS1 A;  1GJV A;  2R05 A;  2CJ4 A;  3GM6 A;  4L1F A;  3CRK A;  3TTB A;  1X8Z A;  3MPJ A;  4ZXV A;  3AFE A;  3D2R A;  1Y8O A;  2EBF X;  2ZO5 A;  3FCJ A;  5M4M A;  2F6L A;  1JQI A;  2OEX A;  2VR0 A;  1JM6 A;  3EOM A;  2Q8G A;  3BNG A;  1OAH A;  1QDB A;  2R0M A;  1S26 A;  1K8T A;  1XFV A;  2JBT A;  4G97 A;  4QIC A;  4V25 A;  3TZ2 A;  3VKG A;  1XG2 B;  3SCE A;  2VF1 A;  4L3X A;  1RP3 A;  2BU8 A;  1GU6 A;  3C2P A;  2CJ5 A;  2FON A;  2PG0 A;  3CE2 A;  2YYJ A;  2YYK A;  4L3Z A;  1Y8N A;  5B5V A;  4Q5B A;  5BRM A;  3TZ5 A;  3C46 A;  2OT4 A;  2GBB A;  1PK0 A;  2Z1Q A;  2BU7 A;  3UBR A;  3Q23 A;  3EON A;  3TZ0 A;  1GKZ A;  1T9G A;  4KSF A;  1RJ4 A;  1UDY A;  3R7K A;  3GNC A;  2BU2 A;  3MDE A;  3CRL A;  2CJ8 A;  1UKW A;  2LFW A;  3F29 A;  4H7Q A;  4JEK A;  4Q17 A;  5GJW E;  4DOY A;  2BU5 A;  5K3G A;  4LQQ B;  1Y0V A;  4DZY A;  3UU9 A;  2IX5 A;  2JBR A;  4P79 A;  1PI1 A;  2FP2 A;  2RFQ A;  2REH A;  5K3J A;  2YYL A;  3N0R A;  2JBS A;  3MPI A;  1XFX A;  4KTO A;  2Q8F A;  4E00 A;  1U8V A;  2EBA A;  3TZ4 A;  2RF7 A;  2FP1 A;  4E02 A;  1R2J A;  2Q8I A;  1R3B A;  4X28 C;  1XFZ A;  2CJ6 A;  3TOR A;  4KSA A;  3MDD A;  4HKS A;  3D1I A;  1EGD A;  1FS8 A;  4JIO A;  3SF6 A;  4FZ4 A;  2JIF A;  4AKH A;  2EBH X;  4FF2 A;  4Q1O A;  1X90 A;  2ZDX A;  4O5M A;  2D29 A;  3D6B A;  4E01 A;  4J1V A;  5K3H A;  1BUC A;  3D9G A;  2UXW A;  3SWO A;  3D9F A;  2OJQ A;  4MP2 A;  4H85 A;  3D9E A;  3M9V A;  3C3L A;  3Q22 A;  2R02 A;  3X0X A;  3VKH A;  4IRN A;  1XFW A;  2AO2 A;  2YYI A;  4L38 A;  5M4K A;  3OIB A;  2RDZ A;  4MPE A;  4F0X A;  1LVC A;  2A1T A;  1EGE A;  3AFF A;  3S7W A;  1IS2 A;  4MPC A;  3PFD A;  4H81 A;  4HKR A;  4N5F A;  3L1T A;  2OR0 A;  3BNH A;  2YYM A;  3II9 A;  3KML A;  4JIZ A;  3LGQ A;  2PO4 A;  2ZAF A;  5J71 A;  4FF3 A;  1XFU A;  1FS7 A;  4AKI A;  4AKG A;  3OWA A;  2E0A A;  2R0N A;  2BTZ A;  2ZKJ A;  4XVX A;  2DDH A;  2YYG A;  2WBI A;  3LG1 A;  4G5E A;  3MKH A;  4W9U A;  1RJ1 A;  4X28 A;  3SXQ A;  5M4N A;  1EGC A;  3Q24 A;  2E80 A;  5J6A A;  4IV6 A;  2AZE A;  2DVL A;  2QR4 A;  4HR3 A;  5BRK A;  1SC5 A;  3Q0A A;  4FF1 A;  3BNF A;  3VAD A;  4LQS B;  5B6B A;  2CJ7 A;  2HJN A;  5GJV E;  1IVH A;  2CX9 A;  2PNR A;  4M9A A;  2C0U A;  3D9D A;  4AI6 A;  4L3Y A;  1Y8P A;  1WS9 A;  4MP7 A;  3OWM A;  1GKX A;  4MPN A;  4OO2 A;  1SIR A;  5M4P A;  2J7A A;  2Q8H A;  4Q4U A;  1FS9 A;  4V26 A;  3NF4 A;  2OEV A;  2XS8 A;  3B96 A;  2EC5 A;  4Q0T A;  4RM7 A;  5B5W A;  1W07 A;  1X91 A;  2BU6 A;  2XQR B;  2ZDY A;  2VIG A;  3BNJ A;  3HWC A;  4KCF A;  4ZYJ A;  2YGW A;  4U83 A;  4Q5C A; 
#chains in the Genus database with same CATH homology
 3GQT A;  1SIQ A;  3FO3 A;  3P4T A;  4WJY A;  3MMO A;  2IX6 A;  3MXL A;  3X0Y A;  2E81 A;  3RKH A;  1RX0 A;  2C12 A;  4NXL A;  4P13 A;  5K3I A;  4L1F A;  3GM6 A;  3TTB A;  3MPJ A;  4ZXV A;  3AFE A;  2ZO5 A;  3FCJ A;  1JQI A;  2VR0 A;  3EOM A;  3BNG A;  1OAH A;  1QDB A;  2R0M A;  2JBT A;  3SCE A;  4L3X A;  1GU6 A;  2FON A;  2PG0 A;  2YYJ A;  2YYK A;  4L3Z A;  4Q5B A;  2OT4 A;  2Z1Q A;  3UBR A;  3EON A;  1T9G A;  1UDY A;  3R7K A;  3GNC A;  3MDE A;  3F29 A;  4Q17 A;  1UKW A;  4JEK A;  5K3G A;  4DOY A;  3UU9 A;  2IX5 A;  2JBR A;  2RFQ A;  2REH A;  5K3J A;  2YYL A;  2JBS A;  3MPI A;  4KTO A;  1U8V A;  2EBA A;  2RF7 A;  1R2J A;  3TOR A;  4X28 C;  3MDD A;  3D1I A;  1EGD A;  1FS8 A;  3SF6 A;  2JIF A;  4Q1O A;  4O5M A;  2D29 A;  3D6B A;  5K3H A;  1BUC A;  3D9G A;  2UXW A;  3SWO A;  3D9F A;  3D9E A;  3M9V A;  3X0X A;  4IRN A;  4L38 A;  2YYI A;  3OIB A;  2RDZ A;  3S7W A;  2A1T A;  1EGE A;  3AFF A;  1IS2 A;  3PFD A;  4N5F A;  3L1T A;  2OR0 A;  3BNH A;  2YYM A;  3II9 A;  3LGQ A;  2ZAF A;  1FS7 A;  3OWA A;  2R0N A;  4XVX A;  2DDH A;  2YYG A;  2WBI A;  3LG1 A;  4G5E A;  3MKH A;  4W9U A;  4X28 A;  3SXQ A;  1EGC A;  2E80 A;  4IV6 A;  2DVL A;  4HR3 A;  3BNF A;  1IVH A;  2CX9 A;  4M9A A;  2C0U A;  3D9D A;  4L3Y A;  1WS9 A;  3OWM A;  4OO2 A;  1SIR A;  2J7A A;  4Q4U A;  1FS9 A;  3NF4 A;  3B96 A;  4Q0T A;  4RM7 A;  1W07 A;  3BNJ A;  2VIG A;  4ZYJ A;  3HWC A;  4KCF A;  4U83 A;  4Q5C A; 
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