4OO2A

Streptomyces globisporus c-1027 fad dependent (s)-3-chloro-β-tyrosine-s-sgcc2 c-5 hydroxylase sgcc apo form
Total Genus 170
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
170
sequence length
510
structure length
506
Chain Sequence
TRPLTGEEYLESLRDAREVYLDGSRVKDVTAHPAFHNPARMTARLYDSLHDPAQKAVLTAPTDAGDGFTHRFFTAPRSVDDLVKDQAAIASWARKSYGWMGRSPDYKASFLGTLGANADFYEPFADNARRWYRESQEKVLYWNHAFLHPPVDRSEVGDVFIHVERETDAGLVVSGAKVVATGSALTHAAFISHWGLPIKDRKFALVATVPMDADGLKVICRPSYSANAATTGSPFDNPLSSRLDENDAILVLDQVLIPWENVFVYGNLGKVHLLAGQSGMIERATFHGCTRLAVKLEFIAGLLAKALDITGAKDFRGVQTRLGEVLAWRNLFWSLSDAAARNPVPWKNGTLLPNPQAGMAYRWFMQIGYPRVLEIVQQDVASGLMYVNSSTEDFRNPETGPYLEKYLRGSDGAGAVERVKVMKLLWDAVGSDFGGRHELYERNYSGNHENTRIELLLSQTASGKLDSYMDFAQACMDEYDLDGWTAPDLESFHAMRSASRDLLGGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Oxidoreductase
molecule keywords Chlorophenol-4-monooxygenase
publication title Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus.
pubmed doi rcsb
source organism Streptomyces globisporus
total genus 170
structure length 506
sequence length 510
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2014-01-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03241 HpaB 4-hydroxyphenylacetate 3-hydroxylase C terminal
A PF11794 HpaB_N 4-hydroxyphenylacetate 3-hydroxylase N terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 4oo2A02
4Q5CA 1T9GA 2DVLA 4M9AA 3FCJA 1SIQA 2YYLA 1BUCA 4N5FA 4JEKA 4U83A 3OWMA 2J7AA 2UXWA 3D9FA 3S7WA 3OIBA 2OR0A 3AFFA 5K3JA 3RKHA 1EGEA 4Q5BA 4L1FA 3MKHA 4Q1OA 5K3GA 1GU6A 2FONA 2RDZA 3M9VA 1RX0A 2YYKA 3BNJA 3F29A 3L1TA 4Q4UA 2YYIA 2JBSA 2IX6A 4L3XA 2A1TA 3BNGA 3SXQA 3D9GA 3D9EA 3AFEA 2ZO5A 1U8VA 1SIRA 3R7KA 2WBIA 3SWOA 2R0NA 5K3IA 3UU9A 3GQTA 1FS7A 2E80A 2ZAFA 4X28C 2CX9A 2REHA 2PG0A 4HR3A 2Z1QA 3II9A 3UBRA 4X28A 4L3YA 4W9UA 1UKWA 1JQIA 2D29A 3EONA 2R0MA 4KCFA 4WJYA 3GNCA 3PFDA 3TTBA 3X0YA 1FS8A 2JBRA 1IVHA 3P4TA 2C0UA 4ZYJA 2E81A 1WS9A 3SCEA 4G5EA 1QDBA 1R2JA 3HWCA 2VIGA 2DDHA 3D1IA 4ZXVA 2JBTA 2RF7A 2RFQA 4IRNA 3GM6A 2YYJA 3MDEA 4L38A 3TORA 2YYGA 3BNFA 1UDYA 4P13A 2JIFA 4DOYA 4Q0TA 3LGQA 3X0XA 4XVXA 1FS9A 3OWAA 1IS2A 3LG1A 2VR0A 2YYMA 3D6BA 4NXLA 4OO2A 4Q17A 4RM7A 3EOMA 3MPIA 4O5MA 2OT4A 2IX5A 1EGCA 3MPJA 4L3ZA 3MXLA 4KTOA 3BNHA 4IV6A 2EBAA 3MDDA 3D9DA 2C12A 3MMOA 1W07A 3B96A 5K3HA 3NF4A 1EGDA 3FO3A 3SF6A 1OAHA
chains in the Genus database with same CATH superfamily
4Q5CA 1XFUA 1JM6A 1T9GA 2DVLA 4E00A 4M9AA 3C3LA 3FCJA 5BRMA 4FF4A 1SIQA 2YYLA 2CJ7A 1BUCA 4KSFA 4N5FA 4JEKA 4U83A 2FP1A 1XFVA 5B5VA 1GJVA 3OWMA 1PK0A 4G97A 2EBHX 4FF3A 2J7AA 2HJNA 3X29A 2UXWA 3D9FA 1X91A 2FP2A 2OR0A 3AFFA 1K8TA 3OIBA 5K3JA 1EGEA 4Q5BA 2BTZA 2OEXA 4L1FA 3RKHA 2BU8A 2XQRB 3CRKA 2XS1A 3MKHA 2Q8HA 4H81A 4Q1OA 5BRKA 5K3GA 1GU6A 2FONA 1X8ZA 2RDZA 1SC5A 3M9VA 4AKHA 1RX0A 2YYKA 3BNJA 3F29A 3L1TA 4Q4UA 2YYIA 5B6BA 5J71A 3Q22A 2CJ5A 2JBSA 1Y0VA 2IX6A 2A1TA 2BU7A 2EC5A 3BNGA 4L3XA 3SXQA 3D9GA 4QICA 1XG2B 1Y8OA 1Y8PA 4KS9A 3D9EA 3AFEA 2ZO5A 2XS8A 1U8VA 1SIRA 1K93A 1GKXA 2QR4A 3R7KA 2WBIA 3SWOA 2R0NA 5K3IA 2OJQA 3UU9A 2OEVA 3GQTA 1FS7A 4MP2A 2E0AA 2E80A 5M4KA 2ZAFA 2Q8IA 4X28C 1GKZA 2CX9A 2R02A 2REHA 4HKSA 4MPNA 2PG0A 4HR3A 5M4PA 4MPEA 2Z1QA 3II9A 3UBRA 2EBFX 4X28A 2BU6A 4L3YA 1XFZA 4W9UA 1UKWA 1JQIA 2D29A 2Q8FA 3D2RA 3EONA 2R0MA 2ZDYA 2ZDXA 4KCFA 2LFWA 4V26A 4FF1A 1RJ4A 1XFXA 2F6LA 4E02A 4WJYA 1R3BA 4J1VA 3GNCA 3PFDA 4HKRA 3TTBA 3X0YA 1FS8A 2JBRA 2PO4A 4KSAA 4H85A 3Q24A 3VKGA 1IVHA 1XFWA 1RP3A 2YGWA 3P4TA 4AKIA 2C0UA 1SK6A 4ZYJA 4FZ4A 2E81A 4AI6A 3TZ4A 3C2PA 1WS9A 2CJ8A 4G5EA 2CJ6A 3SCEA 4DZYA 5GJVE 1QDBA 3Q23A 4H7QA 1R2JA 5M4NA 3CRLA 4JIOA 3HWCA 4V25A 2GBBA 2VIGA 2DDHA 3D1IA 4ZXVA 2JBTA 2RF7A 3TZ5A 2RFQA 4IRNA 4P79A 3GM6A 4F0XA 3VKHA 2ZKJA 4E01A 3CE2A 4LQSB 1XFYA 2YYJA 3MDEA 4L38A 3TORA 4JIZA 2YYGA 2BU2A 3BNFA 5GJWE 3TZ0A 1UDYA 1PI1A 2Q8GA 5M4MA 4P13A 2JIFA 2R05A 3Q0AA 4DOYA 2R03A 4Q0TA 3LGQA 4MP7A 3VADA 3X0XA 2PNRA 3KMLA 4LQQB 2CJ4A 2VF1A 4MPCA 4XVXA 2AO2A 1FS9A 3S7WA 3OWAA 1IS2A 1S26A 1Y8NA 2VR0A 2YYMA 3LG1A 4AKGA 3C46A 5B5WA 3D6BA 4NXLA 4OO2A 3TZ2A 4Q17A 4RM7A 3EOMA 3MPIA 4O5MA 2OT4A 2IX5A 1EGCA 1LVCA 3MPJA 2BU5A 4FF2A 1RJ1A 4L3ZA 3MXLA 4KTOA 3BNHA 4IV6A 2EBAA 3MDDA 3D9DA 2C12A 3MMOA 3N0RA 5J6AA 1W07A 3B96A 5K3HA 1K90A 3NF4A 1EGDA 3FO3A 1X90A 3SF6A 2AZEA 1OAHA
chains in the Genus database with same CATH topology
4Q5CA 1T9GA 2DVLA 4M9AA 3FCJA 1SIQA 2YYLA 1BUCA 4N5FA 4JEKA 4U83A 3OWMA 2J7AA 2UXWA 3D9FA 3S7WA 3OIBA 2OR0A 3AFFA 5K3JA 3RKHA 1EGEA 4Q5BA 4L1FA 3MKHA 4Q1OA 5K3GA 1GU6A 2FONA 2RDZA 3M9VA 1RX0A 2YYKA 3BNJA 3F29A 3L1TA 4Q4UA 2YYIA 2JBSA 2IX6A 4L3XA 2A1TA 3BNGA 3SXQA 3D9GA 3D9EA 3AFEA 2ZO5A 1U8VA 1SIRA 3R7KA 2WBIA 3SWOA 2R0NA 5K3IA 3UU9A 3GQTA 1FS7A 2E80A 2ZAFA 4X28C 2CX9A 2REHA 2PG0A 4HR3A 2Z1QA 3II9A 3UBRA 4X28A 4L3YA 4W9UA 1UKWA 1JQIA 2D29A 3EONA 2R0MA 4KCFA 4WJYA 3GNCA 3PFDA 3TTBA 3X0YA 1FS8A 2JBRA 1IVHA 3P4TA 2C0UA 4ZYJA 2E81A 1WS9A 3SCEA 4G5EA 1QDBA 1R2JA 3HWCA 2VIGA 2DDHA 3D1IA 4ZXVA 2JBTA 2RF7A 2RFQA 4IRNA 3GM6A 2YYJA 3MDEA 4L38A 3TORA 2YYGA 3BNFA 1UDYA 4P13A 2JIFA 4DOYA 4Q0TA 3LGQA 3X0XA 4XVXA 1FS9A 3OWAA 1IS2A 3LG1A 2VR0A 2YYMA 3D6BA 4NXLA 4OO2A 4Q17A 4RM7A 3EOMA 3MPIA 4O5MA 2OT4A 2IX5A 1EGCA 3MPJA 4L3ZA 3MXLA 4KTOA 3BNHA 4IV6A 2EBAA 3MDDA 3D9DA 2C12A 3MMOA 1W07A 3B96A 5K3HA 3NF4A 1EGDA 3FO3A 3SF6A 1OAHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Q5C A;  1T9G A;  2DVL A;  4M9A A;  3FCJ A;  1SIQ A;  2YYL A;  1BUC A;  4N5F A;  4JEK A;  4U83 A;  3OWM A;  2J7A A;  2UXW A;  3D9F A;  3S7W A;  3OIB A;  2OR0 A;  3AFF A;  5K3J A;  3RKH A;  1EGE A;  4Q5B A;  4L1F A;  3MKH A;  4Q1O A;  5K3G A;  1GU6 A;  2FON A;  2RDZ A;  3M9V A;  1RX0 A;  2YYK A;  3BNJ A;  3F29 A;  3L1T A;  4Q4U A;  2YYI A;  2JBS A;  2IX6 A;  4L3X A;  2A1T A;  3BNG A;  3SXQ A;  3D9G A;  3D9E A;  3AFE A;  2ZO5 A;  1U8V A;  1SIR A;  3R7K A;  2WBI A;  3SWO A;  2R0N A;  5K3I A;  3UU9 A;  3GQT A;  1FS7 A;  2E80 A;  2ZAF A;  4X28 C;  2CX9 A;  2REH A;  2PG0 A;  4HR3 A;  2Z1Q A;  3II9 A;  3UBR A;  4X28 A;  4L3Y A;  4W9U A;  1UKW A;  1JQI A;  2D29 A;  3EON A;  2R0M A;  4KCF A;  4WJY A;  3GNC A;  3PFD A;  3TTB A;  3X0Y A;  1FS8 A;  2JBR A;  1IVH A;  3P4T A;  2C0U A;  4ZYJ A;  2E81 A;  1WS9 A;  3SCE A;  4G5E A;  1QDB A;  1R2J A;  3HWC A;  2VIG A;  2DDH A;  3D1I A;  4ZXV A;  2JBT A;  2RF7 A;  2RFQ A;  4IRN A;  3GM6 A;  2YYJ A;  3MDE A;  4L38 A;  3TOR A;  2YYG A;  3BNF A;  1UDY A;  4P13 A;  2JIF A;  4DOY A;  4Q0T A;  3LGQ A;  3X0X A;  4XVX A;  1FS9 A;  3OWA A;  1IS2 A;  3LG1 A;  2VR0 A;  2YYM A;  3D6B A;  4NXL A;  4OO2 A;  4Q17 A;  4RM7 A;  3EOM A;  3MPI A;  4O5M A;  2OT4 A;  2IX5 A;  1EGC A;  3MPJ A;  4L3Z A;  3MXL A;  4KTO A;  3BNH A;  4IV6 A;  2EBA A;  3MDD A;  3D9D A;  2C12 A;  3MMO A;  1W07 A;  3B96 A;  5K3H A;  3NF4 A;  1EGD A;  3FO3 A;  3SF6 A;  1OAH A; 
#chains in the Genus database with same CATH topology
 4Q5C A;  1XFU A;  1JM6 A;  1T9G A;  2DVL A;  4E00 A;  4M9A A;  3C3L A;  3FCJ A;  5BRM A;  4FF4 A;  1SIQ A;  2YYL A;  2CJ7 A;  1BUC A;  4KSF A;  4N5F A;  4JEK A;  4U83 A;  2FP1 A;  1XFV A;  5B5V A;  1GJV A;  3OWM A;  1PK0 A;  4G97 A;  2EBH X;  4FF3 A;  2J7A A;  2HJN A;  3X29 A;  2UXW A;  3D9F A;  1X91 A;  2FP2 A;  2OR0 A;  3AFF A;  1K8T A;  3OIB A;  5K3J A;  1EGE A;  4Q5B A;  2BTZ A;  2OEX A;  4L1F A;  3RKH A;  2BU8 A;  2XQR B;  3CRK A;  2XS1 A;  3MKH A;  2Q8H A;  4H81 A;  4Q1O A;  5BRK A;  5K3G A;  1GU6 A;  2FON A;  1X8Z A;  2RDZ A;  1SC5 A;  3M9V A;  4AKH A;  1RX0 A;  2YYK A;  3BNJ A;  3F29 A;  3L1T A;  4Q4U A;  2YYI A;  5B6B A;  5J71 A;  3Q22 A;  2CJ5 A;  2JBS A;  1Y0V A;  2IX6 A;  2A1T A;  2BU7 A;  2EC5 A;  3BNG A;  4L3X A;  3SXQ A;  3D9G A;  4QIC A;  1XG2 B;  1Y8O A;  1Y8P A;  4KS9 A;  3D9E A;  3AFE A;  2ZO5 A;  2XS8 A;  1U8V A;  1SIR A;  1K93 A;  1GKX A;  2QR4 A;  3R7K A;  2WBI A;  3SWO A;  2R0N A;  5K3I A;  2OJQ A;  3UU9 A;  2OEV A;  3GQT A;  1FS7 A;  4MP2 A;  2E0A A;  2E80 A;  5M4K A;  2ZAF A;  2Q8I A;  4X28 C;  1GKZ A;  2CX9 A;  2R02 A;  2REH A;  4HKS A;  4MPN A;  2PG0 A;  4HR3 A;  5M4P A;  4MPE A;  2Z1Q A;  3II9 A;  3UBR A;  2EBF X;  4X28 A;  2BU6 A;  4L3Y A;  1XFZ A;  4W9U A;  1UKW A;  1JQI A;  2D29 A;  2Q8F A;  3D2R A;  3EON A;  2R0M A;  2ZDY A;  2ZDX A;  4KCF A;  2LFW A;  4V26 A;  4FF1 A;  1RJ4 A;  1XFX A;  2F6L A;  4E02 A;  4WJY A;  1R3B A;  4J1V A;  3GNC A;  3PFD A;  4HKR A;  3TTB A;  3X0Y A;  1FS8 A;  2JBR A;  2PO4 A;  4KSA A;  4H85 A;  3Q24 A;  3VKG A;  1IVH A;  1XFW A;  1RP3 A;  2YGW A;  3P4T A;  4AKI A;  2C0U A;  1SK6 A;  4ZYJ A;  4FZ4 A;  2E81 A;  4AI6 A;  3TZ4 A;  3C2P A;  1WS9 A;  2CJ8 A;  4G5E A;  2CJ6 A;  3SCE A;  4DZY A;  5GJV E;  1QDB A;  3Q23 A;  4H7Q A;  1R2J A;  5M4N A;  3CRL A;  4JIO A;  3HWC A;  4V25 A;  2GBB A;  2VIG A;  2DDH A;  3D1I A;  4ZXV A;  2JBT A;  2RF7 A;  3TZ5 A;  2RFQ A;  4IRN A;  4P79 A;  3GM6 A;  4F0X A;  3VKH A;  2ZKJ A;  4E01 A;  3CE2 A;  4LQS B;  1XFY A;  2YYJ A;  3MDE A;  4L38 A;  3TOR A;  4JIZ A;  2YYG A;  2BU2 A;  3BNF A;  5GJW E;  3TZ0 A;  1UDY A;  1PI1 A;  2Q8G A;  5M4M A;  4P13 A;  2JIF A;  2R05 A;  3Q0A A;  4DOY A;  2R03 A;  4Q0T A;  3LGQ A;  4MP7 A;  3VAD A;  3X0X A;  2PNR A;  3KML A;  4LQQ B;  2CJ4 A;  2VF1 A;  4MPC A;  4XVX A;  2AO2 A;  1FS9 A;  3S7W A;  3OWA A;  1IS2 A;  1S26 A;  1Y8N A;  2VR0 A;  2YYM A;  3LG1 A;  4AKG A;  3C46 A;  5B5W A;  3D6B A;  4NXL A;  4OO2 A;  3TZ2 A;  4Q17 A;  4RM7 A;  3EOM A;  3MPI A;  4O5M A;  2OT4 A;  2IX5 A;  1EGC A;  1LVC A;  3MPJ A;  2BU5 A;  4FF2 A;  1RJ1 A;  4L3Z A;  3MXL A;  4KTO A;  3BNH A;  4IV6 A;  2EBA A;  3MDD A;  3D9D A;  2C12 A;  3MMO A;  3N0R A;  5J6A A;  1W07 A;  3B96 A;  5K3H A;  1K90 A;  3NF4 A;  1EGD A;  3FO3 A;  1X90 A;  3SF6 A;  2AZE A;  1OAH A; 
#chains in the Genus database with same CATH homology
 4Q5C A;  1T9G A;  2DVL A;  4M9A A;  3FCJ A;  1SIQ A;  2YYL A;  1BUC A;  4N5F A;  4JEK A;  4U83 A;  3OWM A;  2J7A A;  2UXW A;  3D9F A;  3S7W A;  3OIB A;  2OR0 A;  3AFF A;  5K3J A;  3RKH A;  1EGE A;  4Q5B A;  4L1F A;  3MKH A;  4Q1O A;  5K3G A;  1GU6 A;  2FON A;  2RDZ A;  3M9V A;  1RX0 A;  2YYK A;  3BNJ A;  3F29 A;  3L1T A;  4Q4U A;  2YYI A;  2JBS A;  2IX6 A;  4L3X A;  2A1T A;  3BNG A;  3SXQ A;  3D9G A;  3D9E A;  3AFE A;  2ZO5 A;  1U8V A;  1SIR A;  3R7K A;  2WBI A;  3SWO A;  2R0N A;  5K3I A;  3UU9 A;  3GQT A;  1FS7 A;  2E80 A;  2ZAF A;  4X28 C;  2CX9 A;  2REH A;  2PG0 A;  4HR3 A;  2Z1Q A;  3II9 A;  3UBR A;  4X28 A;  4L3Y A;  4W9U A;  1UKW A;  1JQI A;  2D29 A;  3EON A;  2R0M A;  4KCF A;  4WJY A;  3GNC A;  3PFD A;  3TTB A;  3X0Y A;  1FS8 A;  2JBR A;  1IVH A;  3P4T A;  2C0U A;  4ZYJ A;  2E81 A;  1WS9 A;  3SCE A;  4G5E A;  1QDB A;  1R2J A;  3HWC A;  2VIG A;  2DDH A;  3D1I A;  4ZXV A;  2JBT A;  2RF7 A;  2RFQ A;  4IRN A;  3GM6 A;  2YYJ A;  3MDE A;  4L38 A;  3TOR A;  2YYG A;  3BNF A;  1UDY A;  4P13 A;  2JIF A;  4DOY A;  4Q0T A;  3LGQ A;  3X0X A;  4XVX A;  1FS9 A;  3OWA A;  1IS2 A;  3LG1 A;  2VR0 A;  2YYM A;  3D6B A;  4NXL A;  4OO2 A;  4Q17 A;  4RM7 A;  3EOM A;  3MPI A;  4O5M A;  2OT4 A;  2IX5 A;  1EGC A;  3MPJ A;  4L3Z A;  3MXL A;  4KTO A;  3BNH A;  4IV6 A;  2EBA A;  3MDD A;  3D9D A;  2C12 A;  3MMO A;  1W07 A;  3B96 A;  5K3H A;  3NF4 A;  1EGD A;  3FO3 A;  3SF6 A;  1OAH A; 
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