3R7KA

Crystal structure of a probable acyl coa dehydrogenase from mycobacterium abscessus atcc 19977 / dsm 44196
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
378
structure length
378
Chain Sequence
PEAWTTPERRALSQMARSFVEREIAPKLAEWEHVGEIPRDLHLNAAEVGLLGIGFPEEVGGSGGNAIDSALVTEAILAAGGSTGVCAALFTHGIALPHIAANGSDALIERYVRPTLAGKMIGSLGVTEPGAGSDVANLRTRAVREGDTYVVNGAKTFITSGVRADFVTTAVRTGGPGYGGVSLLVIDKNSPGFEVSRRLDKMGWRCSDTAELSFVDVRVPADNLVGAENSGFLQIMQQFQAERLGIAVQAYATAGRALDLAKSWARERETFGRPLTGRQIIRHKLAEMARQVDVACTYTRAVMQRWLAGEDVVAEVSMAKNTAVYACDYVVNEAVQIFGGMGYMRESEIERHYRDCRILGIGGGTNEIMNEVIAKRIG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
molecule keywords Probable acyl CoA dehydrogenase
publication title Increasing the structural coverage of tuberculosis drug targets.
pubmed doi rcsb
source organism Mycobacterium abscessus
total genus 141
structure length 378
sequence length 378
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2011-03-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 3r7kA01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 3r7kA03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 3r7kA02
4U83A 3D9FA 3X0YA 3MXLA 3OWAA 2D29A 3S7WA 3SXQA 4XVXA 2YYJA 2R0MA 4L3YA 4RM7A 4IV6A 4Q1OA 4Q5BA 4Q4UA 2JBRA 2PG0A 3D9DA 4N5FA 2IX6A 1IVHA 3HWCA 2YYKA 3AFEA 5K3GA 2E81A 1JQIA 3M9VA 3AFFA 3MPJA 3RKHA 3MKHA 4KTOA 1WS9A 1W07A 2JIFA 2YYLA 3R7KA 4P13A 3TORA 2EBAA 4ZXVA 3MDEA 2YYIA 3EONA 4Q0TA 4OO2A 3L1TA 1RX0A 4Q5CA 4IRNA 2R0NA 2YYGA 4X28C 3EOMA 3LGQA 2A1TA 4L38A 2DDHA 1UKWA 3NF4A 3MDDA 3X0XA 3MMOA 3GQTA 2C12A 4W9UA 3MPIA 3P4TA 2IX5A 5K3JA 3PFDA 4G5EA 4KCFA 3SCEA 1SIQA 2RFQA 4Q17A 2C0UA 1IS2A 3OIBA 3II9A 4NXLA 5K3IA 2UXWA 2REHA 1QDBA 4JEKA 3F29A 4L1FA 3OWMA 1BUCA 3TTBA 1FS8A 2J7AA 3BNGA 2DVLA 2RDZA 4HR3A 5K3HA 2Z1QA 3B96A 3FCJA 1U8VA 1T9GA 3SWOA 4L3ZA 4X28A 2JBTA 3D6BA 2OT4A 2WBIA 2ZO5A 3BNJA 3LG1A 1EGEA 3UBRA 3FO3A 2OR0A 3D9GA 3D9EA 1EGCA 2FONA 2E80A 4DOYA 2VIGA 4ZYJA 1EGDA 2YYMA 3BNHA 2CX9A 2ZAFA 3GNCA 2VR0A 1GU6A 4L3XA 3SF6A 3D1IA 4O5MA 4WJYA 3BNFA 1FS7A 1OAHA 2RF7A 2JBSA 3GM6A 1R2JA 1UDYA 3UU9A 1SIRA 1FS9A 4M9AA
chains in the Genus database with same CATH superfamily
4U83A 3D9FA 5M4KA 3X0YA 3MXLA 2R03A 1K8TA 3OWAA 2D29A 3S7WA 3SXQA 4V26A 1X90A 4XVXA 2PNRA 2R0MA 2YYJA 3D2RA 4L3YA 4DZYA 2F6LA 4RM7A 4IV6A 2CJ4A 4Q1OA 2EBHX 3Q23A 1XFXA 5EZ3A 4Q5BA 2XS1A 2ZDYA 4Q4UA 2JBRA 2PG0A 2BU2A 3D9DA 4N5FA 2IX6A 5M4MA 1IVHA 3HWCA 4AKHA 1RP3A 2YYKA 3AFEA 5K3GA 2E81A 4KS9A 1X8ZA 1JQIA 3M9VA 1GJVA 2R02A 2CJ5A 3CE2A 3AFFA 3TZ4A 3MPJA 3RKHA 3C46A 3MKHA 2BU7A 4KTOA 1WS9A 1W07A 2JIFA 1XFYA 5J71A 2QR4A 1GKZA 2YYLA 3R7KA 4P13A 4FF3A 3TORA 2EBAA 4ZXVA 2OEVA 4FZ4A 4QICA 3MDEA 2BU5A 2YYIA 3EONA 4Q0TA 4OO2A 1XG2B 2R05A 3TZ2A 3L1TA 2Q8IA 3VADA 3Q24A 1RX0A 1SK6A 4IRNA 4P79A 2R0NA 4Q5CA 2BTZA 4AI6A 2CJ7A 3CRLA 5M4PA 3VKHA 2YYGA 4X28C 1Y0VA 3EOMA 3LGQA 2A1TA 4G97A 2DDHA 4L38A 1UKWA 3NF4A 3MDDA 3X0XA 1K90A 2OJQA 3N0RA 4KSFA 3C3LA 1GKXA 3MMOA 2ZDXA 3GQTA 2C12A 4FF2A 4W9UA 4MPEA 3TZ0A 3MPIA 3P4TA 4E01A 2IX5A 5K3JA 3PFDA 4G5EA 4KCFA 3U33A 4JIZA 3SCEA 4FF4A 4AKGA 1SIQA 2RFQA 4Q17A 2E0AA 4H7QA 2OEXA 4E02A 3VKGA 4J1VA 5J6AA 5GJWE 4H81A 2C0UA 3C2PA 1IS2A 3OIBA 3II9A 1LVCA 3CRKA 4NXLA 3KMLA 4HKSA 1RJ1A 2EC5A 2FP1A 4LQQB 5K3IA 1Y8NA 2UXWA 2REHA 1QDBA 4JEKA 1Y8PA 1PI1A 2YGWA 3F29A 4H85A 4L1FA 1R3BA 3OWMA 1BUCA 1S26A 4JIOA 2Q8FA 4KSAA 4E00A 3TTBA 1FS8A 2J7AA 3BNGA 2DVLA 1PK0A 2RDZA 4HR3A 5K3HA 4MP7A 2Z1QA 1X91A 3B96A 3FCJA 2Q8GA 1U8VA 1T9GA 3SWOA 1XFZA 4L3ZA 2Q8HA 3X29A 4X28A 5BRMA 2JBTA 3D6BA 2OT4A 2GBBA 2ZKJA 1SC5A 2PO4A 4MPCA 2WBIA 4AKIA 2XQRB 2ZO5A 2HJNA 3BNJA 3LG1A 5M4NA 1EGEA 3UBRA 3FO3A 2AO2A 1K93A 5B6BA 2VF1A 2OR0A 1Y8OA 4V25A 3D9GA 1JM6A 3D9EA 3Q22A 1EGCA 2FONA 5B5VA 3TZ5A 4F0XA 4LQSB 2BU8A 2E80A 4DOYA 2BU6A 2VIGA 4ZYJA 1EGDA 1XFVA 2CJ6A 2LFWA 2YYMA 3BNHA 5B5WA 2FP2A 3Q0AA 2CX9A 2ZAFA 3GNCA 1XFWA 1GU6A 2VR0A 5GJVE 4L3XA 3SF6A 1RJ4A 2EBFX 3D1IA 4MPNA 4O5MA 4HKRA 4WJYA 3BNFA 5BRKA 1FS7A 2AZEA 1OAHA 2RF7A 4MP2A 2JBSA 3GM6A 1R2JA 1UDYA 2CJ8A 2XS8A 3UU9A 4FF1A 3DJLA 1SIRA 1FS9A 4M9AA 1XFUA
chains in the Genus database with same CATH topology
4U83A 3D9FA 3X0YA 3MXLA 3OWAA 2D29A 3S7WA 3SXQA 4XVXA 2YYJA 2R0MA 4L3YA 4RM7A 4IV6A 4Q1OA 4Q5BA 4Q4UA 2JBRA 2PG0A 3D9DA 4N5FA 2IX6A 1IVHA 3HWCA 2YYKA 3AFEA 5K3GA 2E81A 1JQIA 3M9VA 3AFFA 3MPJA 3RKHA 3MKHA 4KTOA 1WS9A 1W07A 2JIFA 2YYLA 3R7KA 4P13A 3TORA 2EBAA 4ZXVA 3MDEA 2YYIA 3EONA 4Q0TA 4OO2A 3L1TA 1RX0A 4Q5CA 4IRNA 2R0NA 2YYGA 4X28C 3EOMA 3LGQA 2A1TA 4L38A 2DDHA 1UKWA 3NF4A 3MDDA 3X0XA 3MMOA 3GQTA 2C12A 4W9UA 3MPIA 3P4TA 2IX5A 5K3JA 3PFDA 4G5EA 4KCFA 3SCEA 1SIQA 2RFQA 4Q17A 2C0UA 1IS2A 3OIBA 3II9A 4NXLA 5K3IA 2UXWA 2REHA 1QDBA 4JEKA 3F29A 4L1FA 3OWMA 1BUCA 3TTBA 1FS8A 2J7AA 3BNGA 2DVLA 2RDZA 4HR3A 5K3HA 2Z1QA 3B96A 3FCJA 1U8VA 1T9GA 3SWOA 4L3ZA 4X28A 2JBTA 3D6BA 2OT4A 2WBIA 2ZO5A 3BNJA 3LG1A 1EGEA 3UBRA 3FO3A 2OR0A 3D9GA 3D9EA 1EGCA 2FONA 2E80A 4DOYA 2VIGA 4ZYJA 1EGDA 2YYMA 3BNHA 2CX9A 2ZAFA 3GNCA 2VR0A 1GU6A 4L3XA 3SF6A 3D1IA 4O5MA 4WJYA 3BNFA 1FS7A 1OAHA 2RF7A 2JBSA 3GM6A 1R2JA 1UDYA 3UU9A 1SIRA 1FS9A 4M9AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4U83 A;  3D9F A;  3X0Y A;  3MXL A;  3OWA A;  2D29 A;  3S7W A;  3SXQ A;  4XVX A;  2YYJ A;  2R0M A;  4L3Y A;  4RM7 A;  4IV6 A;  4Q1O A;  4Q5B A;  4Q4U A;  2JBR A;  2PG0 A;  3D9D A;  4N5F A;  2IX6 A;  1IVH A;  3HWC A;  2YYK A;  3AFE A;  5K3G A;  2E81 A;  1JQI A;  3M9V A;  3AFF A;  3MPJ A;  3RKH A;  3MKH A;  4KTO A;  1WS9 A;  1W07 A;  2JIF A;  2YYL A;  3R7K A;  4P13 A;  3TOR A;  2EBA A;  4ZXV A;  3MDE A;  2YYI A;  3EON A;  4Q0T A;  4OO2 A;  3L1T A;  1RX0 A;  4Q5C A;  4IRN A;  2R0N A;  2YYG A;  4X28 C;  3EOM A;  3LGQ A;  2A1T A;  4L38 A;  2DDH A;  1UKW A;  3NF4 A;  3MDD A;  3X0X A;  3MMO A;  3GQT A;  2C12 A;  4W9U A;  3MPI A;  3P4T A;  2IX5 A;  5K3J A;  3PFD A;  4G5E A;  4KCF A;  3SCE A;  1SIQ A;  2RFQ A;  4Q17 A;  2C0U A;  1IS2 A;  3OIB A;  3II9 A;  4NXL A;  5K3I A;  2UXW A;  2REH A;  1QDB A;  4JEK A;  3F29 A;  4L1F A;  3OWM A;  1BUC A;  3TTB A;  1FS8 A;  2J7A A;  3BNG A;  2DVL A;  2RDZ A;  4HR3 A;  5K3H A;  2Z1Q A;  3B96 A;  3FCJ A;  1U8V A;  1T9G A;  3SWO A;  4L3Z A;  4X28 A;  2JBT A;  3D6B A;  2OT4 A;  2WBI A;  2ZO5 A;  3BNJ A;  3LG1 A;  1EGE A;  3UBR A;  3FO3 A;  2OR0 A;  3D9G A;  3D9E A;  1EGC A;  2FON A;  2E80 A;  4DOY A;  2VIG A;  4ZYJ A;  1EGD A;  2YYM A;  3BNH A;  2CX9 A;  2ZAF A;  3GNC A;  2VR0 A;  1GU6 A;  4L3X A;  3SF6 A;  3D1I A;  4O5M A;  4WJY A;  3BNF A;  1FS7 A;  1OAH A;  2RF7 A;  2JBS A;  3GM6 A;  1R2J A;  1UDY A;  3UU9 A;  1SIR A;  1FS9 A;  4M9A A; 
#chains in the Genus database with same CATH topology
 4U83 A;  3D9F A;  5M4K A;  3X0Y A;  3MXL A;  2R03 A;  1K8T A;  3OWA A;  2D29 A;  3S7W A;  3SXQ A;  4V26 A;  1X90 A;  4XVX A;  2PNR A;  2R0M A;  2YYJ A;  3D2R A;  4L3Y A;  4DZY A;  2F6L A;  4RM7 A;  4IV6 A;  2CJ4 A;  4Q1O A;  2EBH X;  3Q23 A;  1XFX A;  5EZ3 A;  4Q5B A;  2XS1 A;  2ZDY A;  4Q4U A;  2JBR A;  2PG0 A;  2BU2 A;  3D9D A;  4N5F A;  2IX6 A;  5M4M A;  1IVH A;  3HWC A;  4AKH A;  1RP3 A;  2YYK A;  3AFE A;  5K3G A;  2E81 A;  4KS9 A;  1X8Z A;  1JQI A;  3M9V A;  1GJV A;  2R02 A;  2CJ5 A;  3CE2 A;  3AFF A;  3TZ4 A;  3MPJ A;  3RKH A;  3C46 A;  3MKH A;  2BU7 A;  4KTO A;  1WS9 A;  1W07 A;  2JIF A;  1XFY A;  5J71 A;  2QR4 A;  1GKZ A;  2YYL A;  3R7K A;  4P13 A;  4FF3 A;  3TOR A;  2EBA A;  4ZXV A;  2OEV A;  4FZ4 A;  4QIC A;  3MDE A;  2BU5 A;  2YYI A;  3EON A;  4Q0T A;  4OO2 A;  1XG2 B;  2R05 A;  3TZ2 A;  3L1T A;  2Q8I A;  3VAD A;  3Q24 A;  1RX0 A;  1SK6 A;  4IRN A;  4P79 A;  2R0N A;  4Q5C A;  2BTZ A;  4AI6 A;  2CJ7 A;  3CRL A;  5M4P A;  3VKH A;  2YYG A;  4X28 C;  1Y0V A;  3EOM A;  3LGQ A;  2A1T A;  4G97 A;  2DDH A;  4L38 A;  1UKW A;  3NF4 A;  3MDD A;  3X0X A;  1K90 A;  2OJQ A;  3N0R A;  4KSF A;  3C3L A;  1GKX A;  3MMO A;  2ZDX A;  3GQT A;  2C12 A;  4FF2 A;  4W9U A;  4MPE A;  3TZ0 A;  3MPI A;  3P4T A;  4E01 A;  2IX5 A;  5K3J A;  3PFD A;  4G5E A;  4KCF A;  3U33 A;  4JIZ A;  3SCE A;  4FF4 A;  4AKG A;  1SIQ A;  2RFQ A;  4Q17 A;  2E0A A;  4H7Q A;  2OEX A;  4E02 A;  3VKG A;  4J1V A;  5J6A A;  5GJW E;  4H81 A;  2C0U A;  3C2P A;  1IS2 A;  3OIB A;  3II9 A;  1LVC A;  3CRK A;  4NXL A;  3KML A;  4HKS A;  1RJ1 A;  2EC5 A;  2FP1 A;  4LQQ B;  5K3I A;  1Y8N A;  2UXW A;  2REH A;  1QDB A;  4JEK A;  1Y8P A;  1PI1 A;  2YGW A;  3F29 A;  4H85 A;  4L1F A;  1R3B A;  3OWM A;  1BUC A;  1S26 A;  4JIO A;  2Q8F A;  4KSA A;  4E00 A;  3TTB A;  1FS8 A;  2J7A A;  3BNG A;  2DVL A;  1PK0 A;  2RDZ A;  4HR3 A;  5K3H A;  4MP7 A;  2Z1Q A;  1X91 A;  3B96 A;  3FCJ A;  2Q8G A;  1U8V A;  1T9G A;  3SWO A;  1XFZ A;  4L3Z A;  2Q8H A;  3X29 A;  4X28 A;  5BRM A;  2JBT A;  3D6B A;  2OT4 A;  2GBB A;  2ZKJ A;  1SC5 A;  2PO4 A;  4MPC A;  2WBI A;  4AKI A;  2XQR B;  2ZO5 A;  2HJN A;  3BNJ A;  3LG1 A;  5M4N A;  1EGE A;  3UBR A;  3FO3 A;  2AO2 A;  1K93 A;  5B6B A;  2VF1 A;  2OR0 A;  1Y8O A;  4V25 A;  3D9G A;  1JM6 A;  3D9E A;  3Q22 A;  1EGC A;  2FON A;  5B5V A;  3TZ5 A;  4F0X A;  4LQS B;  2BU8 A;  2E80 A;  4DOY A;  2BU6 A;  2VIG A;  4ZYJ A;  1EGD A;  1XFV A;  2CJ6 A;  2LFW A;  2YYM A;  3BNH A;  5B5W A;  2FP2 A;  3Q0A A;  2CX9 A;  2ZAF A;  3GNC A;  1XFW A;  1GU6 A;  2VR0 A;  5GJV E;  4L3X A;  3SF6 A;  1RJ4 A;  2EBF X;  3D1I A;  4MPN A;  4O5M A;  4HKR A;  4WJY A;  3BNF A;  5BRK A;  1FS7 A;  2AZE A;  1OAH A;  2RF7 A;  4MP2 A;  2JBS A;  3GM6 A;  1R2J A;  1UDY A;  2CJ8 A;  2XS8 A;  3UU9 A;  4FF1 A;  3DJL A;  1SIR A;  1FS9 A;  4M9A A;  1XFU A; 
#chains in the Genus database with same CATH homology
 4U83 A;  3D9F A;  3X0Y A;  3MXL A;  3OWA A;  2D29 A;  3S7W A;  3SXQ A;  4XVX A;  2YYJ A;  2R0M A;  4L3Y A;  4RM7 A;  4IV6 A;  4Q1O A;  4Q5B A;  4Q4U A;  2JBR A;  2PG0 A;  3D9D A;  4N5F A;  2IX6 A;  1IVH A;  3HWC A;  2YYK A;  3AFE A;  5K3G A;  2E81 A;  1JQI A;  3M9V A;  3AFF A;  3MPJ A;  3RKH A;  3MKH A;  4KTO A;  1WS9 A;  1W07 A;  2JIF A;  2YYL A;  3R7K A;  4P13 A;  3TOR A;  2EBA A;  4ZXV A;  3MDE A;  2YYI A;  3EON A;  4Q0T A;  4OO2 A;  3L1T A;  1RX0 A;  4Q5C A;  4IRN A;  2R0N A;  2YYG A;  4X28 C;  3EOM A;  3LGQ A;  2A1T A;  4L38 A;  2DDH A;  1UKW A;  3NF4 A;  3MDD A;  3X0X A;  3MMO A;  3GQT A;  2C12 A;  4W9U A;  3MPI A;  3P4T A;  2IX5 A;  5K3J A;  3PFD A;  4G5E A;  4KCF A;  3SCE A;  1SIQ A;  2RFQ A;  4Q17 A;  2C0U A;  1IS2 A;  3OIB A;  3II9 A;  4NXL A;  5K3I A;  2UXW A;  2REH A;  1QDB A;  4JEK A;  3F29 A;  4L1F A;  3OWM A;  1BUC A;  3TTB A;  1FS8 A;  2J7A A;  3BNG A;  2DVL A;  2RDZ A;  4HR3 A;  5K3H A;  2Z1Q A;  3B96 A;  3FCJ A;  1U8V A;  1T9G A;  3SWO A;  4L3Z A;  4X28 A;  2JBT A;  3D6B A;  2OT4 A;  2WBI A;  2ZO5 A;  3BNJ A;  3LG1 A;  1EGE A;  3UBR A;  3FO3 A;  2OR0 A;  3D9G A;  3D9E A;  1EGC A;  2FON A;  2E80 A;  4DOY A;  2VIG A;  4ZYJ A;  1EGD A;  2YYM A;  3BNH A;  2CX9 A;  2ZAF A;  3GNC A;  2VR0 A;  1GU6 A;  4L3X A;  3SF6 A;  3D1I A;  4O5M A;  4WJY A;  3BNF A;  1FS7 A;  1OAH A;  2RF7 A;  2JBS A;  3GM6 A;  1R2J A;  1UDY A;  3UU9 A;  1SIR A;  1FS9 A;  4M9A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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