3R7KA

Crystal structure of a probable acyl coa dehydrogenase from mycobacterium abscessus atcc 19977 / dsm 44196
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
378
structure length
378
Chain Sequence
PEAWTTPERRALSQMARSFVEREIAPKLAEWEHVGEIPRDLHLNAAEVGLLGIGFPEEVGGSGGNAIDSALVTEAILAAGGSTGVCAALFTHGIALPHIAANGSDALIERYVRPTLAGKMIGSLGVTEPGAGSDVANLRTRAVREGDTYVVNGAKTFITSGVRADFVTTAVRTGGPGYGGVSLLVIDKNSPGFEVSRRLDKMGWRCSDTAELSFVDVRVPADNLVGAENSGFLQIMQQFQAERLGIAVQAYATAGRALDLAKSWARERETFGRPLTGRQIIRHKLAEMARQVDVACTYTRAVMQRWLAGEDVVAEVSMAKNTAVYACDYVVNEAVQIFGGMGYMRESEIERHYRDCRILGIGGGTNEIMNEVIAKRIG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Probable acyl CoA dehydrogenase
publication title Increasing the structural coverage of tuberculosis drug targets.
pubmed doi rcsb
source organism Mycobacterium abscessus
molecule tags Oxidoreductase
total genus 141
structure length 378
sequence length 378
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2011-03-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 3r7kA01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 3r7kA03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 3r7kA02
3GM6A 2D29A 2CX9A 3SCEA 3NF4A 3S7WA 4NXLA 3MDEA 3UBRA 4KCFA 1GU6A 3AFEA 2YYMA 4W9UA 4X28C 4DOYA 2R0NA 3BNHA 1SIQA 3D9FA 2J7AA 5K3JA 4ZYJA 2DVLA 2IX5A 3MPJA 2Z1QA 1FS7A 3F29A 2JBSA 4Q4UA 2C0UA 1OAHA 3OWAA 2OR0A 3MXLA 2ZO5A 2YYIA 4HR3A 4N5FA 3MPIA 1RX0A 3FCJA 2YYLA 4G5EA 3PFDA 4KTOA 4L3ZA 4U83A 3HWCA 3BNGA 4L38A 2RF7A 3D6BA 3FO3A 3TTBA 1EGEA 3RKHA 2RFQA 1QDBA 1EGDA 4Q1OA 4O5MA 4P13A 4ZXVA 1IVHA 2DDHA 1U8VA 2UXWA 1FS9A 1EGCA 5K3HA 1IS2A 3MDDA 2JBRA 3EONA 3UU9A 3AFFA 3BNFA 3P4TA 4XVXA 5K3IA 2JIFA 4IRNA 3D9EA 2WBIA 3SWOA 3D9DA 2OT4A 4L3YA 2VR0A 1JQIA 4IV6A 3X0XA 3MMOA 1WS9A 3L1TA 5K3GA 3GNCA 4Q5BA 2FONA 4Q5CA 2JBTA 4M9AA 2EBAA 4OO2A 3BNJA 3OWMA 4RM7A 1FS8A 3B96A 2E81A 2E80A 1UDYA 3EOMA 2YYJA 4Q0TA 1BUCA 3M9VA 2IX6A 3SXQA 4L3XA 3GQTA 3SF6A 3LG1A 1R2JA 2REHA 2A1TA 4X28A 2YYKA 1UKWA 4Q17A 4WJYA 3LGQA 3II9A 3X0YA 3TORA 2YYGA 1T9GA 2VIGA 3D9GA 1SIRA 4L1FA 3R7KA 2RDZA 1W07A 3OIBA 4JEKA 2C12A 2R0MA 2PG0A 3MKHA 2ZAFA 3D1IA
chains in the Genus database with same CATH superfamily
3GM6A 2D29A 2CX9A 3SCEA 3NF4A 4E01A 3S7WA 4NXLA 3MDEA 2BU5A 3UBRA 4AI6A 4FF1A 4KCFA 1GU6A 3AFEA 2YYMA 4W9UA 4X28C 4DOYA 2R0NA 1RJ1A 3BNHA 5BRKA 1SIQA 3D9FA 2J7AA 4KSFA 4JIZA 1PI1A 5GJWE 5K3JA 3TZ5A 5B6BA 4ZYJA 2DVLA 4FF4A 2IX5A 3D2RA 3MPJA 2FP1A 2Z1QA 1FS7A 4F0XA 3C3LA 2HJNA 2JBSA 3F29A 3KMLA 4Q4UA 2C0UA 5J71A 3Q22A 3Q23A 1OAHA 2EBHX 3OWAA 4FF2A 1Y8OA 2OR0A 3MXLA 4V26A 2Q8FA 3VKHA 2ZO5A 2YYIA 3X29A 2BU8A 4AKIA 4HR3A 2XS1A 4N5FA 4DZYA 3Q24A 2ZDXA 2OEXA 3TZ0A 3MPIA 1RX0A 2BU2A 1SK6A 3FCJA 1XFYA 2YYLA 2CJ4A 1K8TA 4G5EA 3PFDA 4QICA 4AKGA 1XFWA 4E00A 4KTOA 4L3ZA 4P79A 5B5VA 1GKZA 2CJ7A 2AO2A 1XFXA 5M4KA 4U83A 1R3BA 3HWCA 4MPCA 4HKRA 3BNGA 4KS9A 1X91A 3D6BA 2RF7A 3FO3A 4L38A 3TTBA 5M4NA 1EGEA 4H85A 4E02A 3RKHA 2RFQA 1QDBA 2CJ5A 1EGDA 4MP2A 4Q1OA 4O5MA 3DJLA 4P13A 2BTZA 2EBFX 4AKHA 4ZXVA 1LVCA 2Q8HA 2GBBA 5GJVE 1IVHA 2XQRB 3C46A 1PK0A 2DDHA 1U8VA 2BU6A 2UXWA 1FS9A 1EGCA 5K3HA 2PO4A 3VADA 1X90A 1IS2A 1JM6A 3MDDA 3Q0AA 2JBRA 3EONA 3UU9A 3AFFA 3BNFA 2VF1A 3P4TA 4XVXA 2FP2A 2F6LA 1SC5A 5K3IA 1RP3A 2JIFA 4IRNA 3D9EA 2WBIA 3SWOA 4H7QA 3D9DA 2OT4A 1XFVA 2ZDYA 4H81A 3C2PA 4L3YA 2R02A 4V25A 2VR0A 1JQIA 4IV6A 4FZ4A 2XS8A 3X0XA 3CE2A 3MMOA 2Q8IA 2E0AA 1WS9A 2CJ6A 3L1TA 5K3GA 3GNCA 4KSAA 3TZ4A 4MP7A 4FF3A 4Q5BA 2FONA 4Q5CA 2JBTA 1GKXA 1Y8PA 4M9AA 2EBAA 1GJVA 2CJ8A 4OO2A 3BNJA 2PNRA 3OWMA 4J1VA 1XFZA 1Y0VA 2Q8GA 4LQQB 2R03A 3U33A 4RM7A 4MPNA 1FS8A 3B96A 2E81A 2E80A 3N0RA 2EC5A 1UDYA 3EOMA 2OJQA 1XFUA 2YYJA 4Q0TA 1BUCA 4MPEA 3M9VA 4JIOA 5J6AA 1X8ZA 1XG2B 3CRLA 2IX6A 5M4PA 1RJ4A 3CRKA 2AZEA 1K93A 3SXQA 4L3XA 3GQTA 3SF6A 2LFWA 2BU7A 1R2JA 2REHA 2A1TA 3LG1A 4X28A 2YYKA 1UKWA 2OEVA 2YGWA 4LQSB 4Q17A 4WJYA 3LGQA 5M4MA 3II9A 5EZ3A 3X0YA 3TORA 2YYGA 2QR4A 4G97A 1T9GA 2VIGA 1Y8NA 1K90A 3D9GA 5BRMA 1SIRA 4L1FA 3R7KA 2RDZA 2ZKJA 4HKSA 1W07A 3OIBA 4JEKA 2R05A 2C12A 3VKGA 2R0MA 2PG0A 5B5WA 3MKHA 1S26A 3TZ2A 2ZAFA 3D1IA
chains in the Genus database with same CATH topology
3GM6A 2D29A 2CX9A 3SCEA 3NF4A 3S7WA 4NXLA 3MDEA 3UBRA 4KCFA 1GU6A 3AFEA 2YYMA 4W9UA 4X28C 4DOYA 2R0NA 3BNHA 1SIQA 3D9FA 2J7AA 5K3JA 4ZYJA 2DVLA 2IX5A 3MPJA 2Z1QA 1FS7A 3F29A 2JBSA 4Q4UA 2C0UA 1OAHA 3OWAA 2OR0A 3MXLA 2ZO5A 2YYIA 4HR3A 4N5FA 3MPIA 1RX0A 3FCJA 2YYLA 4G5EA 3PFDA 4KTOA 4L3ZA 4U83A 3HWCA 3BNGA 4L38A 2RF7A 3D6BA 3FO3A 3TTBA 1EGEA 3RKHA 2RFQA 1QDBA 1EGDA 4Q1OA 4O5MA 4P13A 4ZXVA 1IVHA 2DDHA 1U8VA 2UXWA 1FS9A 1EGCA 5K3HA 1IS2A 3MDDA 2JBRA 3EONA 3UU9A 3AFFA 3BNFA 3P4TA 4XVXA 5K3IA 2JIFA 4IRNA 3D9EA 2WBIA 3SWOA 3D9DA 2OT4A 4L3YA 2VR0A 1JQIA 4IV6A 3X0XA 3MMOA 1WS9A 3L1TA 5K3GA 3GNCA 4Q5BA 2FONA 4Q5CA 2JBTA 4M9AA 2EBAA 4OO2A 3BNJA 3OWMA 4RM7A 1FS8A 3B96A 2E81A 2E80A 1UDYA 3EOMA 2YYJA 4Q0TA 1BUCA 3M9VA 2IX6A 3SXQA 4L3XA 3GQTA 3SF6A 3LG1A 1R2JA 2REHA 2A1TA 4X28A 2YYKA 1UKWA 4Q17A 4WJYA 3LGQA 3II9A 3X0YA 3TORA 2YYGA 1T9GA 2VIGA 3D9GA 1SIRA 4L1FA 3R7KA 2RDZA 1W07A 3OIBA 4JEKA 2C12A 2R0MA 2PG0A 3MKHA 2ZAFA 3D1IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GM6 A;  2D29 A;  2CX9 A;  3SCE A;  3NF4 A;  3S7W A;  4NXL A;  3MDE A;  3UBR A;  4KCF A;  1GU6 A;  3AFE A;  2YYM A;  4W9U A;  4X28 C;  4DOY A;  2R0N A;  3BNH A;  1SIQ A;  3D9F A;  2J7A A;  5K3J A;  4ZYJ A;  2DVL A;  2IX5 A;  3MPJ A;  2Z1Q A;  1FS7 A;  3F29 A;  2JBS A;  4Q4U A;  2C0U A;  1OAH A;  3OWA A;  2OR0 A;  3MXL A;  2ZO5 A;  2YYI A;  4HR3 A;  4N5F A;  3MPI A;  1RX0 A;  3FCJ A;  2YYL A;  4G5E A;  3PFD A;  4KTO A;  4L3Z A;  4U83 A;  3HWC A;  3BNG A;  4L38 A;  2RF7 A;  3D6B A;  3FO3 A;  3TTB A;  1EGE A;  3RKH A;  2RFQ A;  1QDB A;  1EGD A;  4Q1O A;  4O5M A;  4P13 A;  4ZXV A;  1IVH A;  2DDH A;  1U8V A;  2UXW A;  1FS9 A;  1EGC A;  5K3H A;  1IS2 A;  3MDD A;  2JBR A;  3EON A;  3UU9 A;  3AFF A;  3BNF A;  3P4T A;  4XVX A;  5K3I A;  2JIF A;  4IRN A;  3D9E A;  2WBI A;  3SWO A;  3D9D A;  2OT4 A;  4L3Y A;  2VR0 A;  1JQI A;  4IV6 A;  3X0X A;  3MMO A;  1WS9 A;  3L1T A;  5K3G A;  3GNC A;  4Q5B A;  2FON A;  4Q5C A;  2JBT A;  4M9A A;  2EBA A;  4OO2 A;  3BNJ A;  3OWM A;  4RM7 A;  1FS8 A;  3B96 A;  2E81 A;  2E80 A;  1UDY A;  3EOM A;  2YYJ A;  4Q0T A;  1BUC A;  3M9V A;  2IX6 A;  3SXQ A;  4L3X A;  3GQT A;  3SF6 A;  3LG1 A;  1R2J A;  2REH A;  2A1T A;  4X28 A;  2YYK A;  1UKW A;  4Q17 A;  4WJY A;  3LGQ A;  3II9 A;  3X0Y A;  3TOR A;  2YYG A;  1T9G A;  2VIG A;  3D9G A;  1SIR A;  4L1F A;  3R7K A;  2RDZ A;  1W07 A;  3OIB A;  4JEK A;  2C12 A;  2R0M A;  2PG0 A;  3MKH A;  2ZAF A;  3D1I A; 
#chains in the Genus database with same CATH topology
 3GM6 A;  2D29 A;  2CX9 A;  3SCE A;  3NF4 A;  4E01 A;  3S7W A;  4NXL A;  3MDE A;  2BU5 A;  3UBR A;  4AI6 A;  4FF1 A;  4KCF A;  1GU6 A;  3AFE A;  2YYM A;  4W9U A;  4X28 C;  4DOY A;  2R0N A;  1RJ1 A;  3BNH A;  5BRK A;  1SIQ A;  3D9F A;  2J7A A;  4KSF A;  4JIZ A;  1PI1 A;  5GJW E;  5K3J A;  3TZ5 A;  5B6B A;  4ZYJ A;  2DVL A;  4FF4 A;  2IX5 A;  3D2R A;  3MPJ A;  2FP1 A;  2Z1Q A;  1FS7 A;  4F0X A;  3C3L A;  2HJN A;  2JBS A;  3F29 A;  3KML A;  4Q4U A;  2C0U A;  5J71 A;  3Q22 A;  3Q23 A;  1OAH A;  2EBH X;  3OWA A;  4FF2 A;  1Y8O A;  2OR0 A;  3MXL A;  4V26 A;  2Q8F A;  3VKH A;  2ZO5 A;  2YYI A;  3X29 A;  2BU8 A;  4AKI A;  4HR3 A;  2XS1 A;  4N5F A;  4DZY A;  3Q24 A;  2ZDX A;  2OEX A;  3TZ0 A;  3MPI A;  1RX0 A;  2BU2 A;  1SK6 A;  3FCJ A;  1XFY A;  2YYL A;  2CJ4 A;  1K8T A;  4G5E A;  3PFD A;  4QIC A;  4AKG A;  1XFW A;  4E00 A;  4KTO A;  4L3Z A;  4P79 A;  5B5V A;  1GKZ A;  2CJ7 A;  2AO2 A;  1XFX A;  5M4K A;  4U83 A;  1R3B A;  3HWC A;  4MPC A;  4HKR A;  3BNG A;  4KS9 A;  1X91 A;  3D6B A;  2RF7 A;  3FO3 A;  4L38 A;  3TTB A;  5M4N A;  1EGE A;  4H85 A;  4E02 A;  3RKH A;  2RFQ A;  1QDB A;  2CJ5 A;  1EGD A;  4MP2 A;  4Q1O A;  4O5M A;  3DJL A;  4P13 A;  2BTZ A;  2EBF X;  4AKH A;  4ZXV A;  1LVC A;  2Q8H A;  2GBB A;  5GJV E;  1IVH A;  2XQR B;  3C46 A;  1PK0 A;  2DDH A;  1U8V A;  2BU6 A;  2UXW A;  1FS9 A;  1EGC A;  5K3H A;  2PO4 A;  3VAD A;  1X90 A;  1IS2 A;  1JM6 A;  3MDD A;  3Q0A A;  2JBR A;  3EON A;  3UU9 A;  3AFF A;  3BNF A;  2VF1 A;  3P4T A;  4XVX A;  2FP2 A;  2F6L A;  1SC5 A;  5K3I A;  1RP3 A;  2JIF A;  4IRN A;  3D9E A;  2WBI A;  3SWO A;  4H7Q A;  3D9D A;  2OT4 A;  1XFV A;  2ZDY A;  4H81 A;  3C2P A;  4L3Y A;  2R02 A;  4V25 A;  2VR0 A;  1JQI A;  4IV6 A;  4FZ4 A;  2XS8 A;  3X0X A;  3CE2 A;  3MMO A;  2Q8I A;  2E0A A;  1WS9 A;  2CJ6 A;  3L1T A;  5K3G A;  3GNC A;  4KSA A;  3TZ4 A;  4MP7 A;  4FF3 A;  4Q5B A;  2FON A;  4Q5C A;  2JBT A;  1GKX A;  1Y8P A;  4M9A A;  2EBA A;  1GJV A;  2CJ8 A;  4OO2 A;  3BNJ A;  2PNR A;  3OWM A;  4J1V A;  1XFZ A;  1Y0V A;  2Q8G A;  4LQQ B;  2R03 A;  3U33 A;  4RM7 A;  4MPN A;  1FS8 A;  3B96 A;  2E81 A;  2E80 A;  3N0R A;  2EC5 A;  1UDY A;  3EOM A;  2OJQ A;  1XFU A;  2YYJ A;  4Q0T A;  1BUC A;  4MPE A;  3M9V A;  4JIO A;  5J6A A;  1X8Z A;  1XG2 B;  3CRL A;  2IX6 A;  5M4P A;  1RJ4 A;  3CRK A;  2AZE A;  1K93 A;  3SXQ A;  4L3X A;  3GQT A;  3SF6 A;  2LFW A;  2BU7 A;  1R2J A;  2REH A;  2A1T A;  3LG1 A;  4X28 A;  2YYK A;  1UKW A;  2OEV A;  2YGW A;  4LQS B;  4Q17 A;  4WJY A;  3LGQ A;  5M4M A;  3II9 A;  5EZ3 A;  3X0Y A;  3TOR A;  2YYG A;  2QR4 A;  4G97 A;  1T9G A;  2VIG A;  1Y8N A;  1K90 A;  3D9G A;  5BRM A;  1SIR A;  4L1F A;  3R7K A;  2RDZ A;  2ZKJ A;  4HKS A;  1W07 A;  3OIB A;  4JEK A;  2R05 A;  2C12 A;  3VKG A;  2R0M A;  2PG0 A;  5B5W A;  3MKH A;  1S26 A;  3TZ2 A;  2ZAF A;  3D1I A; 
#chains in the Genus database with same CATH homology
 3GM6 A;  2D29 A;  2CX9 A;  3SCE A;  3NF4 A;  3S7W A;  4NXL A;  3MDE A;  3UBR A;  4KCF A;  1GU6 A;  3AFE A;  2YYM A;  4W9U A;  4X28 C;  4DOY A;  2R0N A;  3BNH A;  1SIQ A;  3D9F A;  2J7A A;  5K3J A;  4ZYJ A;  2DVL A;  2IX5 A;  3MPJ A;  2Z1Q A;  1FS7 A;  3F29 A;  2JBS A;  4Q4U A;  2C0U A;  1OAH A;  3OWA A;  2OR0 A;  3MXL A;  2ZO5 A;  2YYI A;  4HR3 A;  4N5F A;  3MPI A;  1RX0 A;  3FCJ A;  2YYL A;  4G5E A;  3PFD A;  4KTO A;  4L3Z A;  4U83 A;  3HWC A;  3BNG A;  4L38 A;  2RF7 A;  3D6B A;  3FO3 A;  3TTB A;  1EGE A;  3RKH A;  2RFQ A;  1QDB A;  1EGD A;  4Q1O A;  4O5M A;  4P13 A;  4ZXV A;  1IVH A;  2DDH A;  1U8V A;  2UXW A;  1FS9 A;  1EGC A;  5K3H A;  1IS2 A;  3MDD A;  2JBR A;  3EON A;  3UU9 A;  3AFF A;  3BNF A;  3P4T A;  4XVX A;  5K3I A;  2JIF A;  4IRN A;  3D9E A;  2WBI A;  3SWO A;  3D9D A;  2OT4 A;  4L3Y A;  2VR0 A;  1JQI A;  4IV6 A;  3X0X A;  3MMO A;  1WS9 A;  3L1T A;  5K3G A;  3GNC A;  4Q5B A;  2FON A;  4Q5C A;  2JBT A;  4M9A A;  2EBA A;  4OO2 A;  3BNJ A;  3OWM A;  4RM7 A;  1FS8 A;  3B96 A;  2E81 A;  2E80 A;  1UDY A;  3EOM A;  2YYJ A;  4Q0T A;  1BUC A;  3M9V A;  2IX6 A;  3SXQ A;  4L3X A;  3GQT A;  3SF6 A;  3LG1 A;  1R2J A;  2REH A;  2A1T A;  4X28 A;  2YYK A;  1UKW A;  4Q17 A;  4WJY A;  3LGQ A;  3II9 A;  3X0Y A;  3TOR A;  2YYG A;  1T9G A;  2VIG A;  3D9G A;  1SIR A;  4L1F A;  3R7K A;  2RDZ A;  1W07 A;  3OIB A;  4JEK A;  2C12 A;  2R0M A;  2PG0 A;  3MKH A;  2ZAF A;  3D1I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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