3AFFA

Crystal structure of the hsaa monooxygenase from m. tuberculosis
Total Genus 144
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
144
sequence length
388
structure length
366
Chain Sequence
RDAQSVLAAIDNLLPEIRDRAQATEDLRRLPDETVKALDDVGFFTLLQPQQWGGLQCDPALFFEATRRLASVCGSTGWVSSIVGVHNWHLALFDQRAQEEVWGEDPSTRISSSYAPMGAGVVVDGGYLVNGSWNWSSGCDHASWTFVGGPVIKDGRPVDFGSFLIPRSEYEIKDVWYVVGLRGTGSNTLVVKDVFVPRHRFLSYKAMNDHTAGGLATNSAPVYKMPWGTMHPTTISAPIVGMAYGAYAAHVEHQIAEAASDIDAAWRQLIGNVSDEYALLAAGKEIPFELRARARRDQVRATGRSIASIDRLFEASGATALSNEAPIQRFWRDAHAGRVHAANDPERAYVIFGNHEFGLPPGDTMV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
molecule keywords Hydroxylase, putative
publication title A flavin-dependent monooxygenase from Mycobacterium tuberculosis involved in cholesterol catabolism
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 144
structure length 366
sequence length 388
chains with identical sequence B
ec nomenclature ec 1.14.14.12: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase.
pdb deposition date 2010-02-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08028 Acyl-CoA_dh_2 Acyl-CoA dehydrogenase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 3affA01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 3affA03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 3affA02
2VIGA 3SCEA 3UU9A 3FO3A 1U8VA 2YYLA 1EGCA 4NXLA 2UXWA 3D9GA 4IRNA 2C0UA 4L3YA 4Q5CA 1SIQA 1EGDA 2A1TA 2J7AA 2JBSA 1FS9A 4WJYA 1T9GA 4M9AA 2YYIA 1IS2A 4OO2A 1JQIA 4DOYA 3MMOA 4U83A 1W07A 1IVHA 3MPIA 4JEKA 1FS8A 2YYMA 3D9DA 1BUCA 3EONA 2JIFA 1GU6A 2D29A 2EBAA 4Q0TA 4IV6A 4ZYJA 4RM7A 4L38A 4KTOA 3NF4A 3OWMA 2FONA 2E81A 2E80A 2DVLA 2IX6A 3BNHA 2REHA 4ZXVA 3MKHA 3GQTA 3BNJA 3BNGA 2ZAFA 3HWCA 3X0YA 2WBIA 4HR3A 2DDHA 3GNCA 2R0NA 4L3ZA 3AFEA 4L3XA 5K3JA 3P4TA 3PFDA 3BNFA 1QDBA 3B96A 3AFFA 3LGQA 2IX5A 2RF7A 3SWOA 4P13A 2RFQA 3M9VA 1UKWA 2YYGA 3MDEA 3LG1A 4KCFA 4W9UA 2VR0A 2PG0A 3OIBA 4X28A 3F29A 1UDYA 4O5MA 2C12A 2CX9A 3SXQA 3TORA 3S7WA 1RX0A 3MDDA 3D9EA 4XVXA 2ZO5A 1FS7A 2RDZA 4N5FA 3FCJA 4Q4UA 3X0XA 3R7KA 4Q1OA 2YYKA 3D9FA 3MPJA 3D1IA 4Q17A 3OWAA 4X28C 2OT4A 3UBRA 5K3GA 1WS9A 1R2JA 2OR0A 1OAHA 3GM6A 3D6BA 5K3HA 3EOMA 2JBTA 5K3IA 2R0MA 3RKHA 4G5EA 1SIRA 4Q5BA 3II9A 3L1TA 2Z1QA 3MXLA 2YYJA 1EGEA 2JBRA 3SF6A 3TTBA 4L1FA
chains in the Genus database with same CATH superfamily
1SC5A 2VIGA 2HJNA 2LFWA 3SCEA 3FO3A 3UU9A 4FF1A 1U8VA 2Q8HA 2YYLA 1K8TA 1GKXA 5BRMA 4DZYA 4E00A 1EGCA 1S26A 4V26A 4NXLA 4LQQB 5BRKA 2UXWA 3D9GA 4IRNA 3CRLA 5J71A 2C0UA 4L3YA 2VF1A 4G97A 4Q5CA 1SIQA 4AKIA 3DJLA 1EGDA 2A1TA 2J7AA 2JBSA 1FS9A 2R02A 1T9GA 2BU7A 4M9AA 4MPCA 4WJYA 2BU6A 4H7QA 1PK0A 2YYIA 1IS2A 2AO2A 1PI1A 2EBHX 4OO2A 1JQIA 4DOYA 3MMOA 4U83A 1W07A 1IVHA 3MPIA 1X90A 1XFXA 3D2RA 3CE2A 1Y0VA 5J6AA 4JEKA 1FS8A 2YYMA 3D9DA 1RJ4A 1BUCA 3EONA 3Q24A 2JIFA 2E0AA 3VKGA 2XS1A 2Q8GA 2CJ5A 1XFWA 1GU6A 1R3BA 2D29A 2OEXA 4FF3A 1Y8PA 1RP3A 4FF4A 2EBAA 4KSAA 4Q0TA 1XFVA 2PO4A 4IV6A 4ZYJA 2Q8IA 4RM7A 2BU8A 4L38A 4KTOA 4H85A 3NF4A 1Y8OA 3OWMA 3VADA 2FONA 2E81A 1GKZA 1XFYA 2ZDYA 5M4KA 2E80A 2DVLA 2IX6A 5M4NA 2BTZA 2ZKJA 3BNHA 4MP2A 2CJ4A 2EC5A 4E01A 5GJVE 2REHA 4ZXVA 3MKHA 5B5WA 3GQTA 3BNJA 3BNGA 2ZAFA 3HWCA 3TZ5A 3X0YA 2WBIA 4MP7A 4HR3A 2DDHA 2CJ8A 2OJQA 3GNCA 2R0NA 4L3ZA 3AFEA 4L3XA 5K3JA 5GJWE 3P4TA 3PFDA 2YGWA 5M4MA 3BNFA 1QDBA 3TZ0A 3U33A 3B96A 1K93A 1LVCA 1XFUA 3AFFA 3LGQA 2IX5A 4E02A 2RF7A 3SWOA 4HKSA 2OEVA 3Q22A 4P13A 2RFQA 4KSFA 4KS9A 3C2PA 3TZ4A 3M9VA 1UKWA 2CJ6A 2XS8A 2YYGA 3MDEA 3LG1A 4KCFA 1XFZA 4MPNA 4W9UA 4JIZA 2Q8FA 3Q23A 2FP2A 1X8ZA 2VR0A 2PG0A 3KMLA 3OIBA 4X28A 1XG2B 3F29A 1UDYA 4O5MA 2C12A 2CX9A 2BU5A 3SXQA 3TORA 1K90A 1RX0A 3S7WA 3MDDA 3D9EA 4MPEA 4XVXA 1SK6A 2ZO5A 1FS7A 4HKRA 2RDZA 4H81A 3X29A 4N5FA 5EZ3A 3FCJA 4Q4UA 4AI6A 4V25A 3C3LA 2R03A 3X0XA 3R7KA 2AZEA 2CJ7A 3CRKA 4Q1OA 1X91A 2YYKA 3D9FA 3MPJA 3D1IA 4Q17A 1GJVA 3VKHA 2EBFX 3OWAA 4X28C 4FZ4A 2OT4A 1Y8NA 4F0XA 3UBRA 5B6BA 4QICA 5K3GA 4AKHA 4JIOA 2PNRA 1RJ1A 1WS9A 1R2JA 2OR0A 1OAHA 3GM6A 4LQSB 2ZDXA 5B5VA 3N0RA 2R05A 2F6LA 3D6BA 5M4PA 5K3HA 1JM6A 3EOMA 2JBTA 5K3IA 3TZ2A 2GBBA 2R0MA 2BU2A 4AKGA 3RKHA 2XQRB 4G5EA 1SIRA 3C46A 4Q5BA 2QR4A 3II9A 3L1TA 2FP1A 2Z1QA 3MXLA 2YYJA 3Q0AA 1EGEA 2JBRA 3SF6A 4FF2A 4P79A 3TTBA 4L1FA 4J1VA
chains in the Genus database with same CATH topology
2VIGA 3SCEA 3UU9A 3FO3A 1U8VA 2YYLA 1EGCA 4NXLA 2UXWA 3D9GA 4IRNA 2C0UA 4L3YA 4Q5CA 1SIQA 1EGDA 2A1TA 2J7AA 2JBSA 1FS9A 4WJYA 1T9GA 4M9AA 2YYIA 1IS2A 4OO2A 1JQIA 4DOYA 3MMOA 4U83A 1W07A 1IVHA 3MPIA 4JEKA 1FS8A 2YYMA 3D9DA 1BUCA 3EONA 2JIFA 1GU6A 2D29A 2EBAA 4Q0TA 4IV6A 4ZYJA 4RM7A 4L38A 4KTOA 3NF4A 3OWMA 2FONA 2E81A 2E80A 2DVLA 2IX6A 3BNHA 2REHA 4ZXVA 3MKHA 3GQTA 3BNJA 3BNGA 2ZAFA 3HWCA 3X0YA 2WBIA 4HR3A 2DDHA 3GNCA 2R0NA 4L3ZA 3AFEA 4L3XA 5K3JA 3P4TA 3PFDA 3BNFA 1QDBA 3B96A 3AFFA 3LGQA 2IX5A 2RF7A 3SWOA 4P13A 2RFQA 3M9VA 1UKWA 2YYGA 3MDEA 3LG1A 4KCFA 4W9UA 2VR0A 2PG0A 3OIBA 4X28A 3F29A 1UDYA 4O5MA 2C12A 2CX9A 3SXQA 3TORA 3S7WA 1RX0A 3MDDA 3D9EA 4XVXA 2ZO5A 1FS7A 2RDZA 4N5FA 3FCJA 4Q4UA 3X0XA 3R7KA 4Q1OA 2YYKA 3D9FA 3MPJA 3D1IA 4Q17A 3OWAA 4X28C 2OT4A 3UBRA 5K3GA 1WS9A 1R2JA 2OR0A 1OAHA 3GM6A 3D6BA 5K3HA 3EOMA 2JBTA 5K3IA 2R0MA 3RKHA 4G5EA 1SIRA 4Q5BA 3II9A 3L1TA 2Z1QA 3MXLA 2YYJA 1EGEA 2JBRA 3SF6A 3TTBA 4L1FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VIG A;  3SCE A;  3UU9 A;  3FO3 A;  1U8V A;  2YYL A;  1EGC A;  4NXL A;  2UXW A;  3D9G A;  4IRN A;  2C0U A;  4L3Y A;  4Q5C A;  1SIQ A;  1EGD A;  2A1T A;  2J7A A;  2JBS A;  1FS9 A;  4WJY A;  1T9G A;  4M9A A;  2YYI A;  1IS2 A;  4OO2 A;  1JQI A;  4DOY A;  3MMO A;  4U83 A;  1W07 A;  1IVH A;  3MPI A;  4JEK A;  1FS8 A;  2YYM A;  3D9D A;  1BUC A;  3EON A;  2JIF A;  1GU6 A;  2D29 A;  2EBA A;  4Q0T A;  4IV6 A;  4ZYJ A;  4RM7 A;  4L38 A;  4KTO A;  3NF4 A;  3OWM A;  2FON A;  2E81 A;  2E80 A;  2DVL A;  2IX6 A;  3BNH A;  2REH A;  4ZXV A;  3MKH A;  3GQT A;  3BNJ A;  3BNG A;  2ZAF A;  3HWC A;  3X0Y A;  2WBI A;  4HR3 A;  2DDH A;  3GNC A;  2R0N A;  4L3Z A;  3AFE A;  4L3X A;  5K3J A;  3P4T A;  3PFD A;  3BNF A;  1QDB A;  3B96 A;  3AFF A;  3LGQ A;  2IX5 A;  2RF7 A;  3SWO A;  4P13 A;  2RFQ A;  3M9V A;  1UKW A;  2YYG A;  3MDE A;  3LG1 A;  4KCF A;  4W9U A;  2VR0 A;  2PG0 A;  3OIB A;  4X28 A;  3F29 A;  1UDY A;  4O5M A;  2C12 A;  2CX9 A;  3SXQ A;  3TOR A;  3S7W A;  1RX0 A;  3MDD A;  3D9E A;  4XVX A;  2ZO5 A;  1FS7 A;  2RDZ A;  4N5F A;  3FCJ A;  4Q4U A;  3X0X A;  3R7K A;  4Q1O A;  2YYK A;  3D9F A;  3MPJ A;  3D1I A;  4Q17 A;  3OWA A;  4X28 C;  2OT4 A;  3UBR A;  5K3G A;  1WS9 A;  1R2J A;  2OR0 A;  1OAH A;  3GM6 A;  3D6B A;  5K3H A;  3EOM A;  2JBT A;  5K3I A;  2R0M A;  3RKH A;  4G5E A;  1SIR A;  4Q5B A;  3II9 A;  3L1T A;  2Z1Q A;  3MXL A;  2YYJ A;  1EGE A;  2JBR A;  3SF6 A;  3TTB A;  4L1F A; 
#chains in the Genus database with same CATH topology
 1SC5 A;  2VIG A;  2HJN A;  2LFW A;  3SCE A;  3FO3 A;  3UU9 A;  4FF1 A;  1U8V A;  2Q8H A;  2YYL A;  1K8T A;  1GKX A;  5BRM A;  4DZY A;  4E00 A;  1EGC A;  1S26 A;  4V26 A;  4NXL A;  4LQQ B;  5BRK A;  2UXW A;  3D9G A;  4IRN A;  3CRL A;  5J71 A;  2C0U A;  4L3Y A;  2VF1 A;  4G97 A;  4Q5C A;  1SIQ A;  4AKI A;  3DJL A;  1EGD A;  2A1T A;  2J7A A;  2JBS A;  1FS9 A;  2R02 A;  1T9G A;  2BU7 A;  4M9A A;  4MPC A;  4WJY A;  2BU6 A;  4H7Q A;  1PK0 A;  2YYI A;  1IS2 A;  2AO2 A;  1PI1 A;  2EBH X;  4OO2 A;  1JQI A;  4DOY A;  3MMO A;  4U83 A;  1W07 A;  1IVH A;  3MPI A;  1X90 A;  1XFX A;  3D2R A;  3CE2 A;  1Y0V A;  5J6A A;  4JEK A;  1FS8 A;  2YYM A;  3D9D A;  1RJ4 A;  1BUC A;  3EON A;  3Q24 A;  2JIF A;  2E0A A;  3VKG A;  2XS1 A;  2Q8G A;  2CJ5 A;  1XFW A;  1GU6 A;  1R3B A;  2D29 A;  2OEX A;  4FF3 A;  1Y8P A;  1RP3 A;  4FF4 A;  2EBA A;  4KSA A;  4Q0T A;  1XFV A;  2PO4 A;  4IV6 A;  4ZYJ A;  2Q8I A;  4RM7 A;  2BU8 A;  4L38 A;  4KTO A;  4H85 A;  3NF4 A;  1Y8O A;  3OWM A;  3VAD A;  2FON A;  2E81 A;  1GKZ A;  1XFY A;  2ZDY A;  5M4K A;  2E80 A;  2DVL A;  2IX6 A;  5M4N A;  2BTZ A;  2ZKJ A;  3BNH A;  4MP2 A;  2CJ4 A;  2EC5 A;  4E01 A;  5GJV E;  2REH A;  4ZXV A;  3MKH A;  5B5W A;  3GQT A;  3BNJ A;  3BNG A;  2ZAF A;  3HWC A;  3TZ5 A;  3X0Y A;  2WBI A;  4MP7 A;  4HR3 A;  2DDH A;  2CJ8 A;  2OJQ A;  3GNC A;  2R0N A;  4L3Z A;  3AFE A;  4L3X A;  5K3J A;  5GJW E;  3P4T A;  3PFD A;  2YGW A;  5M4M A;  3BNF A;  1QDB A;  3TZ0 A;  3U33 A;  3B96 A;  1K93 A;  1LVC A;  1XFU A;  3AFF A;  3LGQ A;  2IX5 A;  4E02 A;  2RF7 A;  3SWO A;  4HKS A;  2OEV A;  3Q22 A;  4P13 A;  2RFQ A;  4KSF A;  4KS9 A;  3C2P A;  3TZ4 A;  3M9V A;  1UKW A;  2CJ6 A;  2XS8 A;  2YYG A;  3MDE A;  3LG1 A;  4KCF A;  1XFZ A;  4MPN A;  4W9U A;  4JIZ A;  2Q8F A;  3Q23 A;  2FP2 A;  1X8Z A;  2VR0 A;  2PG0 A;  3KML A;  3OIB A;  4X28 A;  1XG2 B;  3F29 A;  1UDY A;  4O5M A;  2C12 A;  2CX9 A;  2BU5 A;  3SXQ A;  3TOR A;  1K90 A;  1RX0 A;  3S7W A;  3MDD A;  3D9E A;  4MPE A;  4XVX A;  1SK6 A;  2ZO5 A;  1FS7 A;  4HKR A;  2RDZ A;  4H81 A;  3X29 A;  4N5F A;  5EZ3 A;  3FCJ A;  4Q4U A;  4AI6 A;  4V25 A;  3C3L A;  2R03 A;  3X0X A;  3R7K A;  2AZE A;  2CJ7 A;  3CRK A;  4Q1O A;  1X91 A;  2YYK A;  3D9F A;  3MPJ A;  3D1I A;  4Q17 A;  1GJV A;  3VKH A;  2EBF X;  3OWA A;  4X28 C;  4FZ4 A;  2OT4 A;  1Y8N A;  4F0X A;  3UBR A;  5B6B A;  4QIC A;  5K3G A;  4AKH A;  4JIO A;  2PNR A;  1RJ1 A;  1WS9 A;  1R2J A;  2OR0 A;  1OAH A;  3GM6 A;  4LQS B;  2ZDX A;  5B5V A;  3N0R A;  2R05 A;  2F6L A;  3D6B A;  5M4P A;  5K3H A;  1JM6 A;  3EOM A;  2JBT A;  5K3I A;  3TZ2 A;  2GBB A;  2R0M A;  2BU2 A;  4AKG A;  3RKH A;  2XQR B;  4G5E A;  1SIR A;  3C46 A;  4Q5B A;  2QR4 A;  3II9 A;  3L1T A;  2FP1 A;  2Z1Q A;  3MXL A;  2YYJ A;  3Q0A A;  1EGE A;  2JBR A;  3SF6 A;  4FF2 A;  4P79 A;  3TTB A;  4L1F A;  4J1V A; 
#chains in the Genus database with same CATH homology
 2VIG A;  3SCE A;  3UU9 A;  3FO3 A;  1U8V A;  2YYL A;  1EGC A;  4NXL A;  2UXW A;  3D9G A;  4IRN A;  2C0U A;  4L3Y A;  4Q5C A;  1SIQ A;  1EGD A;  2A1T A;  2J7A A;  2JBS A;  1FS9 A;  4WJY A;  1T9G A;  4M9A A;  2YYI A;  1IS2 A;  4OO2 A;  1JQI A;  4DOY A;  3MMO A;  4U83 A;  1W07 A;  1IVH A;  3MPI A;  4JEK A;  1FS8 A;  2YYM A;  3D9D A;  1BUC A;  3EON A;  2JIF A;  1GU6 A;  2D29 A;  2EBA A;  4Q0T A;  4IV6 A;  4ZYJ A;  4RM7 A;  4L38 A;  4KTO A;  3NF4 A;  3OWM A;  2FON A;  2E81 A;  2E80 A;  2DVL A;  2IX6 A;  3BNH A;  2REH A;  4ZXV A;  3MKH A;  3GQT A;  3BNJ A;  3BNG A;  2ZAF A;  3HWC A;  3X0Y A;  2WBI A;  4HR3 A;  2DDH A;  3GNC A;  2R0N A;  4L3Z A;  3AFE A;  4L3X A;  5K3J A;  3P4T A;  3PFD A;  3BNF A;  1QDB A;  3B96 A;  3AFF A;  3LGQ A;  2IX5 A;  2RF7 A;  3SWO A;  4P13 A;  2RFQ A;  3M9V A;  1UKW A;  2YYG A;  3MDE A;  3LG1 A;  4KCF A;  4W9U A;  2VR0 A;  2PG0 A;  3OIB A;  4X28 A;  3F29 A;  1UDY A;  4O5M A;  2C12 A;  2CX9 A;  3SXQ A;  3TOR A;  3S7W A;  1RX0 A;  3MDD A;  3D9E A;  4XVX A;  2ZO5 A;  1FS7 A;  2RDZ A;  4N5F A;  3FCJ A;  4Q4U A;  3X0X A;  3R7K A;  4Q1O A;  2YYK A;  3D9F A;  3MPJ A;  3D1I A;  4Q17 A;  3OWA A;  4X28 C;  2OT4 A;  3UBR A;  5K3G A;  1WS9 A;  1R2J A;  2OR0 A;  1OAH A;  3GM6 A;  3D6B A;  5K3H A;  3EOM A;  2JBT A;  5K3I A;  2R0M A;  3RKH A;  4G5E A;  1SIR A;  4Q5B A;  3II9 A;  3L1T A;  2Z1Q A;  3MXL A;  2YYJ A;  1EGE A;  2JBR A;  3SF6 A;  3TTB A;  4L1F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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