2YYLA

Crystal structure of the mutant of hpab (t198i, a276g, and r466h) complexed with fad
Total Genus 179
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
179
sequence length
476
structure length
476
Chain Sequence
ARTGAEYIEALKTRPPNLWYKGEKVEDPTTHPVFRGIVRTMAALYDLQHDPRYREVLTYEEEGKRHGMSFLIPKTKEDLKRRGQAYKLWADQNLGMMGRSPDYLNAVVMAYAASADYFGEFAENVRNYYRYLRDQDLATTHALTNPQVNRARPPSGQPDPYIPVGVVKQTEKGIVVRGARMTATFPLADEVLIFPSILLQAGSEKYALAFALPTSTPGLHFVCREALVGGDSPFDHPLSSRVEEMDCLVIFDDVLVPWERVFILGNVELCNNAYGATGALNHMAHQVVALKTAKTEAFLGVAALMAEGIGADVYGHVQEKIAEIIVYLEAMRAFWTRAEEEAKENAYGLLVPDRGALDGARNLYPRLYPRIREILEQIGASGLITLPSEKDFKGPLGPFLEKFLQGAALEAKERVALFRLAWDMTLSGFGARQELYERFFFGDPVRMYQTLYNVYNKEPYKERIHAFLKESLKVFE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords 4-hydroxyphenylacetate-3-hydroxylase
publication title Crystal Structure of the Oxygenase Component (HpaB) of the 4-Hydroxyphenylacetate 3-Monooxygenase from Thermus thermophilus HB8
pubmed doi rcsb
source organism Thermus thermophilus
molecule tags Oxidoreductase
total genus 179
structure length 476
sequence length 476
ec nomenclature ec 1.14.14.9: 4-hydroxyphenylacetate 3-monooxygenase.
pdb deposition date 2007-04-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03241 HpaB 4-hydroxyphenylacetate 3-hydroxylase C terminal
A PF11794 HpaB_N 4-hydroxyphenylacetate 3-hydroxylase N terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3140.10 Mainly Alpha Orthogonal Bundle 4-hydroxybutyryl-coa dehydratase, domain 1 4-hydroxybutyryl-coa dehydratase, domain 1 2yylA01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 2yylA03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 2yylA02
3MDDA 2A1TA 3LG1A 3II9A 3OWMA 2EBAA 1W07A 2FONA 2PG0A 2OT4A 1IS2A 3D9DA 3UBRA 4N5FA 2ZAFA 3SWOA 4IV6A 2CX9A 1FS9A 4Q5CA 3MMOA 4KTOA 2IX5A 1FS8A 2E80A 1WS9A 2J7AA 1GU6A 1FS7A 4ZXVA 4U83A 4DOYA 3D9GA 2OR0A 3MXLA 4NXLA 3GQTA 3D1IA 3LGQA 1IVHA 4IRNA 4ZYJA 3D9FA 1EGEA 1SIRA 2ZO5A 3B96A 4XVXA 2D29A 4L38A 2YYLA 2Z1QA 3RKHA 1JQIA 1UKWA 3X0YA 2R0MA 3BNHA 1RX0A 3GM6A 3TTBA 3GNCA 2YYKA 1T9GA 2R0NA 3SCEA 1BUCA 4L3XA 4L3ZA 3FO3A 3M9VA 4P13A 1SIQA 2REHA 3OWAA 4X28A 2JBTA 1QDBA 2C0UA 2RF7A 3TORA 2VIGA 5K3IA 3AFEA 4L3YA 4L1FA 3NF4A 2YYJA 3SF6A 4O5MA 2JBSA 3D6BA 4JEKA 4OO2A 3EONA 4X28C 3S7WA 2IX6A 2E81A 3MPJA 2YYGA 4Q5BA 3X0XA 3L1TA 3OIBA 4Q1OA 3EOMA 3R7KA 2UXWA 3HWCA 1EGCA 2YYIA 4KCFA 2C12A 2DDHA 2RDZA 3PFDA 4Q4UA 2WBIA 5K3HA 5K3GA 1UDYA 2VR0A 2JBRA 2YYMA 3F29A 4RM7A 1OAHA 3UU9A 5K3JA 2JIFA 3D9EA 3P4TA 4Q0TA 3BNGA 4M9AA 3FCJA 3MKHA 4HR3A 4W9UA 4Q17A 1R2JA 3SXQA 1EGDA 2RFQA 1U8VA 3BNJA 3MDEA 4WJYA 4G5EA 3AFFA 3BNFA 3MPIA 2DVLA
chains in the Genus database with same CATH superfamily
3MDDA 2A1TA 4FF3A 4AKIA 2CJ5A 3LG1A 2BU6A 3II9A 3OWMA 4FZ4A 2EBAA 5J71A 3Q0AA 1XFXA 1W07A 2FONA 2PG0A 4H7QA 4DZYA 5BRKA 2OT4A 4AKHA 1IS2A 3D9DA 4MP2A 4J1VA 3UBRA 4N5FA 5J6AA 2BU2A 2ZAFA 4JIZA 2FP2A 4V25A 3SWOA 2Q8IA 4IV6A 2CX9A 2OEVA 1FS9A 4Q5CA 3MMOA 4KTOA 1JM6A 2IX5A 1FS8A 2E80A 5BRMA 4E01A 1WS9A 2J7AA 2QR4A 4E00A 3U33A 1SC5A 1GU6A 1FS7A 2EBHX 1XFVA 1X90A 4MPCA 1GKZA 4ZXVA 4U83A 2F6LA 1S26A 2AO2A 4DOYA 1PK0A 3D9GA 2OR0A 1XFWA 1XFYA 3MXLA 3DJLA 1RJ1A 4NXLA 3GQTA 3D1IA 3LGQA 1IVHA 1LVCA 4G97A 3D9FA 4IRNA 4F0XA 2VF1A 1EGEA 4ZYJA 5M4KA 1SIRA 3Q22A 2ZO5A 3B96A 4XVXA 2D29A 4L38A 2YYLA 3TZ5A 2Z1QA 1RP3A 3RKHA 2EBFX 2GBBA 1JQIA 1UKWA 4KSFA 1K90A 1Y8OA 2CJ8A 2R0MA 3BNHA 1RX0A 3X0YA 3GM6A 3Q23A 1X91A 4P79A 3TTBA 3GNCA 2YYKA 1GKXA 1X8ZA 2AZEA 1T9GA 3D2RA 1GJVA 3VKGA 2R0NA 3SCEA 4HKSA 1BUCA 4H85A 4L3XA 1RJ4A 4L3ZA 2R05A 3FO3A 2BU5A 3M9VA 4P13A 4FF1A 1SIQA 2REHA 3OWAA 4X28A 2JBTA 1QDBA 2C0UA 2R02A 2RF7A 2VIGA 5K3IA 3AFEA 4L3YA 2Q8HA 4L1FA 2R03A 4FF2A 2BU7A 3NF4A 2YYJA 2Q8FA 3SF6A 4O5MA 2JBSA 3TZ0A 3D6BA 4HKRA 4JEKA 5M4PA 4OO2A 1K93A 3CRKA 3EONA 4X28C 4QICA 3S7WA 4FF4A 2IX6A 4JIOA 1PI1A 2E81A 4KSAA 3TZ2A 3MPJA 3X29A 2Q8GA 2CJ6A 1Y0VA 5B6BA 2YYGA 3CE2A 4Q5BA 3L1TA 3OIBA 2ZDXA 3X0XA 3CRLA 4Q1OA 3C3LA 3EOMA 3C2PA 3R7KA 4KS9A 4AI6A 2UXWA 3HWCA 1EGCA 2YYIA 4KCFA 2E0AA 1R3BA 2BTZA 4MPEA 3N0RA 4E02A 2C12A 2DDHA 2RDZA 3PFDA 4Q4UA 3VKHA 2WBIA 5K3HA 4LQQB 1Y8PA 1UDYA 5K3GA 1K8TA 2VR0A 3VADA 5GJWE 2CJ4A 2JBRA 2ZKJA 2YYMA 3TZ4A 2HJNA 3F29A 2BU8A 4LQSB 2PNRA 4RM7A 5EZ3A 2CJ7A 2LFWA 1OAHA 2XS1A 3UU9A 5K3JA 1SK6A 1XFZA 2JIFA 3KMLA 3D9EA 5GJVE 3P4TA 4Q0TA 3BNGA 1XG2B 2YGWA 4M9AA 3FCJA 3MKHA 3TORA 1XFUA 4HR3A 4V26A 4W9UA 2PO4A 2FP1A 4H81A 4Q17A 5M4MA 1R2JA 3SXQA 1EGDA 5M4NA 4MP7A 2RFQA 1U8VA 1Y8NA 2ZDYA 3BNJA 3MDEA 4WJYA 2OJQA 3Q24A 3C46A 4G5EA 2OEXA 4AKGA 2EC5A 3AFFA 3BNFA 3MPIA 4MPNA 5B5VA 5B5WA 2XQRB 2DVLA 2XS8A
chains in the Genus database with same CATH topology
3MDDA 2A1TA 3LG1A 3II9A 3OWMA 2EBAA 1W07A 2FONA 2PG0A 2OT4A 1IS2A 3D9DA 3UBRA 4N5FA 2ZAFA 3SWOA 4IV6A 2CX9A 1FS9A 4Q5CA 3MMOA 4KTOA 2IX5A 1FS8A 2E80A 1WS9A 2J7AA 1GU6A 1FS7A 4ZXVA 4U83A 4DOYA 3D9GA 2OR0A 3MXLA 4NXLA 3GQTA 3D1IA 3LGQA 1IVHA 4IRNA 4ZYJA 3D9FA 1EGEA 1SIRA 2ZO5A 3B96A 4XVXA 2D29A 4L38A 2YYLA 2Z1QA 3RKHA 1JQIA 1UKWA 3X0YA 2R0MA 3BNHA 1RX0A 3GM6A 3TTBA 3GNCA 2YYKA 1T9GA 2R0NA 3SCEA 1BUCA 4L3XA 4L3ZA 3FO3A 3M9VA 4P13A 1SIQA 2REHA 3OWAA 4X28A 2JBTA 1QDBA 2C0UA 2RF7A 3TORA 2VIGA 5K3IA 3AFEA 4L3YA 4L1FA 3NF4A 2YYJA 3SF6A 4O5MA 2JBSA 3D6BA 4JEKA 4OO2A 3EONA 4X28C 3S7WA 2IX6A 2E81A 3MPJA 2YYGA 4Q5BA 3X0XA 3L1TA 3OIBA 4Q1OA 3EOMA 3R7KA 2UXWA 3HWCA 1EGCA 2YYIA 4KCFA 2C12A 2DDHA 2RDZA 3PFDA 4Q4UA 2WBIA 5K3HA 5K3GA 1UDYA 2VR0A 2JBRA 2YYMA 3F29A 4RM7A 1OAHA 3UU9A 5K3JA 2JIFA 3D9EA 3P4TA 4Q0TA 3BNGA 4M9AA 3FCJA 3MKHA 4HR3A 4W9UA 4Q17A 1R2JA 3SXQA 1EGDA 2RFQA 1U8VA 3BNJA 3MDEA 4WJYA 4G5EA 3AFFA 3BNFA 3MPIA 2DVLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MDD A;  2A1T A;  3LG1 A;  3II9 A;  3OWM A;  2EBA A;  1W07 A;  2FON A;  2PG0 A;  2OT4 A;  1IS2 A;  3D9D A;  3UBR A;  4N5F A;  2ZAF A;  3SWO A;  4IV6 A;  2CX9 A;  1FS9 A;  4Q5C A;  3MMO A;  4KTO A;  2IX5 A;  1FS8 A;  2E80 A;  1WS9 A;  2J7A A;  1GU6 A;  1FS7 A;  4ZXV A;  4U83 A;  4DOY A;  3D9G A;  2OR0 A;  3MXL A;  4NXL A;  3GQT A;  3D1I A;  3LGQ A;  1IVH A;  4IRN A;  4ZYJ A;  3D9F A;  1EGE A;  1SIR A;  2ZO5 A;  3B96 A;  4XVX A;  2D29 A;  4L38 A;  2YYL A;  2Z1Q A;  3RKH A;  1JQI A;  1UKW A;  3X0Y A;  2R0M A;  3BNH A;  1RX0 A;  3GM6 A;  3TTB A;  3GNC A;  2YYK A;  1T9G A;  2R0N A;  3SCE A;  1BUC A;  4L3X A;  4L3Z A;  3FO3 A;  3M9V A;  4P13 A;  1SIQ A;  2REH A;  3OWA A;  4X28 A;  2JBT A;  1QDB A;  2C0U A;  2RF7 A;  3TOR A;  2VIG A;  5K3I A;  3AFE A;  4L3Y A;  4L1F A;  3NF4 A;  2YYJ A;  3SF6 A;  4O5M A;  2JBS A;  3D6B A;  4JEK A;  4OO2 A;  3EON A;  4X28 C;  3S7W A;  2IX6 A;  2E81 A;  3MPJ A;  2YYG A;  4Q5B A;  3X0X A;  3L1T A;  3OIB A;  4Q1O A;  3EOM A;  3R7K A;  2UXW A;  3HWC A;  1EGC A;  2YYI A;  4KCF A;  2C12 A;  2DDH A;  2RDZ A;  3PFD A;  4Q4U A;  2WBI A;  5K3H A;  5K3G A;  1UDY A;  2VR0 A;  2JBR A;  2YYM A;  3F29 A;  4RM7 A;  1OAH A;  3UU9 A;  5K3J A;  2JIF A;  3D9E A;  3P4T A;  4Q0T A;  3BNG A;  4M9A A;  3FCJ A;  3MKH A;  4HR3 A;  4W9U A;  4Q17 A;  1R2J A;  3SXQ A;  1EGD A;  2RFQ A;  1U8V A;  3BNJ A;  3MDE A;  4WJY A;  4G5E A;  3AFF A;  3BNF A;  3MPI A;  2DVL A; 
#chains in the Genus database with same CATH topology
 3MDD A;  2A1T A;  4FF3 A;  4AKI A;  2CJ5 A;  3LG1 A;  2BU6 A;  3II9 A;  3OWM A;  4FZ4 A;  2EBA A;  5J71 A;  3Q0A A;  1XFX A;  1W07 A;  2FON A;  2PG0 A;  4H7Q A;  4DZY A;  5BRK A;  2OT4 A;  4AKH A;  1IS2 A;  3D9D A;  4MP2 A;  4J1V A;  3UBR A;  4N5F A;  5J6A A;  2BU2 A;  2ZAF A;  4JIZ A;  2FP2 A;  4V25 A;  3SWO A;  2Q8I A;  4IV6 A;  2CX9 A;  2OEV A;  1FS9 A;  4Q5C A;  3MMO A;  4KTO A;  1JM6 A;  2IX5 A;  1FS8 A;  2E80 A;  5BRM A;  4E01 A;  1WS9 A;  2J7A A;  2QR4 A;  4E00 A;  3U33 A;  1SC5 A;  1GU6 A;  1FS7 A;  2EBH X;  1XFV A;  1X90 A;  4MPC A;  1GKZ A;  4ZXV A;  4U83 A;  2F6L A;  1S26 A;  2AO2 A;  4DOY A;  1PK0 A;  3D9G A;  2OR0 A;  1XFW A;  1XFY A;  3MXL A;  3DJL A;  1RJ1 A;  4NXL A;  3GQT A;  3D1I A;  3LGQ A;  1IVH A;  1LVC A;  4G97 A;  3D9F A;  4IRN A;  4F0X A;  2VF1 A;  1EGE A;  4ZYJ A;  5M4K A;  1SIR A;  3Q22 A;  2ZO5 A;  3B96 A;  4XVX A;  2D29 A;  4L38 A;  2YYL A;  3TZ5 A;  2Z1Q A;  1RP3 A;  3RKH A;  2EBF X;  2GBB A;  1JQI A;  1UKW A;  4KSF A;  1K90 A;  1Y8O A;  2CJ8 A;  2R0M A;  3BNH A;  1RX0 A;  3X0Y A;  3GM6 A;  3Q23 A;  1X91 A;  4P79 A;  3TTB A;  3GNC A;  2YYK A;  1GKX A;  1X8Z A;  2AZE A;  1T9G A;  3D2R A;  1GJV A;  3VKG A;  2R0N A;  3SCE A;  4HKS A;  1BUC A;  4H85 A;  4L3X A;  1RJ4 A;  4L3Z A;  2R05 A;  3FO3 A;  2BU5 A;  3M9V A;  4P13 A;  4FF1 A;  1SIQ A;  2REH A;  3OWA A;  4X28 A;  2JBT A;  1QDB A;  2C0U A;  2R02 A;  2RF7 A;  2VIG A;  5K3I A;  3AFE A;  4L3Y A;  2Q8H A;  4L1F A;  2R03 A;  4FF2 A;  2BU7 A;  3NF4 A;  2YYJ A;  2Q8F A;  3SF6 A;  4O5M A;  2JBS A;  3TZ0 A;  3D6B A;  4HKR A;  4JEK A;  5M4P A;  4OO2 A;  1K93 A;  3CRK A;  3EON A;  4X28 C;  4QIC A;  3S7W A;  4FF4 A;  2IX6 A;  4JIO A;  1PI1 A;  2E81 A;  4KSA A;  3TZ2 A;  3MPJ A;  3X29 A;  2Q8G A;  2CJ6 A;  1Y0V A;  5B6B A;  2YYG A;  3CE2 A;  4Q5B A;  3L1T A;  3OIB A;  2ZDX A;  3X0X A;  3CRL A;  4Q1O A;  3C3L A;  3EOM A;  3C2P A;  3R7K A;  4KS9 A;  4AI6 A;  2UXW A;  3HWC A;  1EGC A;  2YYI A;  4KCF A;  2E0A A;  1R3B A;  2BTZ A;  4MPE A;  3N0R A;  4E02 A;  2C12 A;  2DDH A;  2RDZ A;  3PFD A;  4Q4U A;  3VKH A;  2WBI A;  5K3H A;  4LQQ B;  1Y8P A;  1UDY A;  5K3G A;  1K8T A;  2VR0 A;  3VAD A;  5GJW E;  2CJ4 A;  2JBR A;  2ZKJ A;  2YYM A;  3TZ4 A;  2HJN A;  3F29 A;  2BU8 A;  4LQS B;  2PNR A;  4RM7 A;  5EZ3 A;  2CJ7 A;  2LFW A;  1OAH A;  2XS1 A;  3UU9 A;  5K3J A;  1SK6 A;  1XFZ A;  2JIF A;  3KML A;  3D9E A;  5GJV E;  3P4T A;  4Q0T A;  3BNG A;  1XG2 B;  2YGW A;  4M9A A;  3FCJ A;  3MKH A;  3TOR A;  1XFU A;  4HR3 A;  4V26 A;  4W9U A;  2PO4 A;  2FP1 A;  4H81 A;  4Q17 A;  5M4M A;  1R2J A;  3SXQ A;  1EGD A;  5M4N A;  4MP7 A;  2RFQ A;  1U8V A;  1Y8N A;  2ZDY A;  3BNJ A;  3MDE A;  4WJY A;  2OJQ A;  3Q24 A;  3C46 A;  4G5E A;  2OEX A;  4AKG A;  2EC5 A;  3AFF A;  3BNF A;  3MPI A;  4MPN A;  5B5V A;  5B5W A;  2XQR B;  2DVL A;  2XS8 A; 
#chains in the Genus database with same CATH homology
 3MDD A;  2A1T A;  3LG1 A;  3II9 A;  3OWM A;  2EBA A;  1W07 A;  2FON A;  2PG0 A;  2OT4 A;  1IS2 A;  3D9D A;  3UBR A;  4N5F A;  2ZAF A;  3SWO A;  4IV6 A;  2CX9 A;  1FS9 A;  4Q5C A;  3MMO A;  4KTO A;  2IX5 A;  1FS8 A;  2E80 A;  1WS9 A;  2J7A A;  1GU6 A;  1FS7 A;  4ZXV A;  4U83 A;  4DOY A;  3D9G A;  2OR0 A;  3MXL A;  4NXL A;  3GQT A;  3D1I A;  3LGQ A;  1IVH A;  4IRN A;  4ZYJ A;  3D9F A;  1EGE A;  1SIR A;  2ZO5 A;  3B96 A;  4XVX A;  2D29 A;  4L38 A;  2YYL A;  2Z1Q A;  3RKH A;  1JQI A;  1UKW A;  3X0Y A;  2R0M A;  3BNH A;  1RX0 A;  3GM6 A;  3TTB A;  3GNC A;  2YYK A;  1T9G A;  2R0N A;  3SCE A;  1BUC A;  4L3X A;  4L3Z A;  3FO3 A;  3M9V A;  4P13 A;  1SIQ A;  2REH A;  3OWA A;  4X28 A;  2JBT A;  1QDB A;  2C0U A;  2RF7 A;  3TOR A;  2VIG A;  5K3I A;  3AFE A;  4L3Y A;  4L1F A;  3NF4 A;  2YYJ A;  3SF6 A;  4O5M A;  2JBS A;  3D6B A;  4JEK A;  4OO2 A;  3EON A;  4X28 C;  3S7W A;  2IX6 A;  2E81 A;  3MPJ A;  2YYG A;  4Q5B A;  3X0X A;  3L1T A;  3OIB A;  4Q1O A;  3EOM A;  3R7K A;  2UXW A;  3HWC A;  1EGC A;  2YYI A;  4KCF A;  2C12 A;  2DDH A;  2RDZ A;  3PFD A;  4Q4U A;  2WBI A;  5K3H A;  5K3G A;  1UDY A;  2VR0 A;  2JBR A;  2YYM A;  3F29 A;  4RM7 A;  1OAH A;  3UU9 A;  5K3J A;  2JIF A;  3D9E A;  3P4T A;  4Q0T A;  3BNG A;  4M9A A;  3FCJ A;  3MKH A;  4HR3 A;  4W9U A;  4Q17 A;  1R2J A;  3SXQ A;  1EGD A;  2RFQ A;  1U8V A;  3BNJ A;  3MDE A;  4WJY A;  4G5E A;  3AFF A;  3BNF A;  3MPI A;  2DVL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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